Genomes and Genes
Summary: A response to a cue that is instrumental in avoiding a noxious experience.
Publications348 found, 100 shown here
- Inhibition of hippocampal Jun N-terminal kinase enhances short-term memory but blocks long-term memory formation and retrieval of an inhibitory avoidance taskLia R M Bevilaqua
Centro de Memoria, Departamento de Bioquimica, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul, Ramiro Barcellos 2600 Anexo Porto Alegre, RS 90035 003, Brazil
Eur J Neurosci 17:897-902. 2003..enhanced short-term memory (STM) but blocked long-term memory (LTM) formation and retrieval of an inhibitory avoidance learning task. No action of this drug on locomotor/exploratory activity or general anxiety state could be detected...
- Storage of spatial information by the maintenance mechanism of LTPEva Pastalkova
Departments of Physiology, Pharmacology, and Neurology, Robert F Furchgott Center for Neural and Behavioral Science, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
Science 313:1141-4. 2006..Thus, the mechanism maintaining LTP sustains spatial memory...
- Amygdala inhibitory circuits and the control of fear memoryIngrid Ehrlich
Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland
Neuron 62:757-71. 2009..Here, we review current understanding and emerging concepts of how local inhibitory circuits in the amygdala control the acquisition, expression, and extinction of conditioned fear at different levels...
- The habenula: from stress evasion to value-based decision-makingOkihide Hikosaka
National Eye Institute, National Institutes of Health, Bethesda, MD 20892 4435, USA
Nat Rev Neurosci 11:503-13. 2010..As a highly conserved structure in the brain, the habenula provides a fundamental mechanism for both survival and decision-making...
- The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responsesThomas C Jhou
Behavioral Neuroscience Branch, National Institute on Drug Abuse, Baltimore, MD 21224, USA
Neuron 61:786-800. 2009..These findings suggest that aversive inputs from widespread brain regions and stimulus modalities converge onto the RMTg, which opposes reward and motor-activating functions of midbrain dopamine neurons...
- Is avoiding an aversive outcome rewarding? Neural substrates of avoidance learning in the human brainHackjin Kim
PLoS Biol 4:e233. 2006b>Avoidance learning poses a challenge for reinforcement-based theories of instrumental conditioning, because once an aversive outcome is successfully avoided an individual may no longer experience extrinsic reinforcement for their behavior...
- Gamma neurons mediate dopaminergic input during aversive olfactory memory formation in DrosophilaHongtao Qin
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
Curr Biol 22:608-14. 2012..We argue that DA-mediated CS-US association is formed in γ neurons followed by communication between γ and α/β neurons to drive consolidation...
- Functional neuroanatomy of aversion and its anticipationJack B Nitschke
The Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Department of Psychiatry, University of Wisconsin, 1500 Highland Avenue, Madison, WI 53705 2280, USA
Neuroimage 29:106-16. 2006..These results show that anticipation of aversion recruits key brain regions that respond to aversion, thereby potentially enhancing adaptive responses to aversive events...
- Opponent appetitive-aversive neural processes underlie predictive learning of pain reliefBen Seymour
Wellcome Department of Imaging Neuroscience, 12 Queen Square, London WC1N 3BG, UK
Nat Neurosci 8:1234-40. 2005..This dual coding has parallels to 'opponent process' theories in psychology and promotes a formal account of prediction and expectation during pain...
- Detection and avoidance of a carnivore odor by preyDavid M Ferrero
Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 108:11235-40. 2011..These data show how a single, volatile chemical detected in the environment can drive an elaborate danger-associated behavioral response in mammals...
- Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotoninSteven J Shabel
Center for Neural Circuits and Behavior, Division of Biology, Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093, USA
Neuron 74:475-81. 2012..Our results also provide a link between antireward excitatory synapses and serotonin, a neuromodulator implicated in depression...
- Regulation of aversion to noxious food by Drosophila neuropeptide Y- and insulin-like systemsQi Wu
Department of Cellular Biology and Biomedical and Health Sciences Institute, University of Georgia, 724 Biological Sciences Building, Athens, Georgia 30602, USA
Nat Neurosci 8:1350-5. 2005..Our results suggest that the coordinated activities of the conserved NPY- and insulin-like receptor signaling systems are essential for the dynamic regulation of noxious food intake according to the animal's energy state...
- Changes in brain activity related to eating chocolate: from pleasure to aversionD M Small
Neuropsychology Cognitive Neuroscience Unit, and Northwestern Cognitive Brain Mapping Group, Northwestern University School of Medicine, Chicago, IL 60611, USA
Brain 124:1720-33. 2001..Therefore, these results support the hypothesis that there are two separate motivational systems: one orchestrating approach and another avoidance behaviours...
- Heat avoidance is regulated by transient receptor potential (TRP) channels and a neuropeptide signaling pathway in Caenorhabditis elegansDominique A Glauser
Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305, USA
Genetics 188:91-103. 2011..Our results show that TRPV channels and the FLP-21/NPR-1 neuropeptide signaling pathway determine the threshold for heat avoidance in C. elegans...
- Mosquitoes smell and avoid the insect repellent DEETZainulabeuddin Syed
Honorary Maeda Duffey Laboratory, Department of Entomology, University of California Davis, 1 Shields Ave, Davis, CA 95616
Proc Natl Acad Sci U S A 105:13598-603. 2008..In a sugar-feeding assay, both female and male mosquitoes avoided DEET. In addition, mosquitoes responding only to physical stimuli avoided DEET...
- Neural circuits and mechanisms involved in Pavlovian fear conditioning: a critical reviewJeansok J Kim
Department of Psychology and Program in Neurobiology and Behavior, University of Washington, Guthrie Hall, Seattle, WA 98195 1525, USA
Neurosci Biobehav Rev 30:188-202. 2006..The purpose of this review is to critically evaluate the strengths and weaknesses of evidence indicating that fear conditioning depend crucially upon the amygdalar circuit and plasticity...
- Critical roles for anterior insula and dorsal striatum in punishment-based avoidance learningStefano Palminteri
Motivation, Brain and Behavior MBB Team, Institut du Cerveau et de la Moëlle épinière ICM, Hopital de la Pitie Salpetriere, 75013 Paris, France
Neuron 76:998-1009. 2012....
- Ascorbic acid supplementation could affect passive avoidance learning and memory in ratSiamak Shahidi
Department of Physiology, Hamadan University of Medical Sciences, Hamedan, Iran
Brain Res Bull 76:109-13. 2008..of acute, short- and long-term pre-training administration of ascorbic acid (60,120 mg/kg) on passive avoidance learning (PAL) and memory in rats. Retention test was done 24h after training...
- Treadmill exercise enhances passive avoidance learning in rats: the role of down-regulated serotonin system in the limbic systemHsiun Ing Chen
Department of Physiology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan
Neurobiol Learn Mem 89:489-96. 2008..Our results demonstrated that treadmill exercise (1) improved the passive avoidance learning performance; (2) decreased the 5-HT level in the hippocampus; (3) decreased the expression of 5-HT(1A) ..
- Synaptic potentiation onto habenula neurons in the learned helplessness model of depressionBo Li
Center for Neural Circuits and Behavior, Department of Neuroscience, University of California at San Diego, La Jolla, California 92093, USA
Nature 470:535-9. 2011..Our results indicate that increased presynaptic action onto LHb neurons contributes to the rodent learned helplessness model of depression...
- Persistence of long-term memory storage requires a late protein synthesis- and BDNF- dependent phase in the hippocampusPedro Bekinschtein
Instituto de Biologia Celular y Neurociencias, UBA, Buenos Aires C1121ABG, Argentina
Neuron 53:261-77. 2007..We propose that memory formation and memory persistence share some of the same molecular mechanisms and that recurrent rounds of consolidation-like events take place in the hippocampus for maintenance of the memory trace...
- Neural correlates of response reversal: considering acquisitionS Budhani
Department of Psychology, University College London, London WC1E 6BT, UK
Neuroimage 34:1754-65. 2007..The implications of these data for recent accounts of response reversal and of response reversal impairments in specific neuropsychiatric populations are discussed...
- Social modulation of learning in ratsEwelina Knapska
Department of Psychology, University of Michigan, Ann Arbor, 48109, USA
Learn Mem 17:35-42. 2010..We argue that socially transferred fear is an adaptation that promotes defensive behavior to potentially dangerous situations in the environment...
- The impact of facial emotional expressions on behavioral tendencies in women and menEva Maria Seidel
Department of Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
J Exp Psychol Hum Percept Perform 36:500-7. 2010..Moreover, our results highlight the importance of gender of poser effects when applying emotional expressions as stimuli...
- Emotional memory impairments in a genetic rat model of depression: involvement of 5-HT/MEK/Arc signaling in restorationT M Eriksson
Center of Molecular Medicine, Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden
Mol Psychiatry 17:173-84. 2012....
- Blockade of 5-HT 1B receptors facilitates contextual aversive learning in mice by disinhibition of cholinergic and glutamatergic neurotransmissionTherese M Eriksson
Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
Neuropharmacology 54:1041-50. 2008..Blockade of brain 5-HT(1B) heteroreceptors may represent a novel therapeutic strategy for restoration of deficient cholinergic and glutamatergic neurotransmission contributing to memory disorders...
- Dopamine and octopamine influence avoidance learning of honey bees in a place preference assayMaitreyi Agarwal
Department of Chemistry, University of Puerto Rico, San Juan, Puerto Rico
PLoS ONE 6:e25371. 2011..avoidance conditioning assay to probe effects of biogenic amines octopamine (OA) and dopamine (DA) on avoidance learning. In this new protocol non-harnessed bees associate a spatial color cue with mild electric shock punishment...
- General learning ability regulates exploration through its influence on rate of habituationKenneth R Light
Rutgers University, Department of Psychology, Piscataway, NJ 08854, USA
Behav Brain Res 223:297-309. 2011..In total, these results indicate that the relationship between exploration and general learning abilities is accounted for by the impact of habituation (itself a form of learning) on behaviors indicative of exploration...
- Effect of donepezil and lercanidipine on memory impairment induced by intracerebroventricular streptozotocin in ratsSwapnil Sonkusare
Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S A S Nagar 160062, Punjab, India
Life Sci 77:1-14. 2005..3 mg/kg) showed significant improvement in memory. When administered together, the effect of combination of these two drugs on memory and cholinesterase activity was higher than that obtained with either of the drugs when used alone...
- Minocycline synergizes with N-acetylcysteine and improves cognition and memory following traumatic brain injury in ratsSamah G Abdel Baki
Departments of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, New York, United States of America
PLoS ONE 5:e12490. 2010..The drugs examined (minocycline (MINO), N-acetylcysteine (NAC), simvastatin, cyclosporine A, and progesterone) had FDA-approval for uses other than TBI and limited brain injury in experimental TBI models...
- Ghrelin enhances olfactory sensitivity and exploratory sniffing in rodents and humansJenny Tong
Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio 45267, USA
J Neurosci 31:5841-6. 2011..This novel role is consistent with ghrelin's overall function as a signal amplifier at the molecular interface between environmental and nutritional cues and neuroendocrine circuits controlling energy homeostasis...
- Intraamygdaloid microinjection of acylated-ghrelin influences passive avoidance learningKrisztián Tóth
Institute of Physiology, Pecs University Medical School, Pecs, Hungary
Behav Brain Res 202:308-11. 2009..Our results suggest that intraamygdaloid A-Ghr enhances learning processes and memory in aversive situations, and this effect can specifically be prevented by ANT pretreatment...
- Effects of ventral tegmental area stimulation on the acquisition and long-term retention of active avoidance learningAnton Ilango
Leibniz Institute for Neurobiology, Brenneckestrasse 6, D 39118 Magdeburg, Germany
Behav Brain Res 225:515-21. 2011The development of avoidance learning depends on dopamine release in forebrain regions. Previous studies indicated that rewarding brain stimulation facilitated two-way active avoidance learning...
- Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brainM R Picciotto
CNRS UA D1284 Neurobiologie Moleculaire, Institut Pasteur, Paris, France
Nature 374:65-7. 1995..Paradoxically, mutant mice are able to perform better than their non-mutant siblings on this task...
- Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouseValentine Bouet
UMR 6185 CNRS, Neurodegenerescence models and therapeutic strategies, University of Caen Basse Normandie, Cyceron, Bd H Becquerel BP 5229, F 14074 Caen cedex, France
Exp Neurol 203:555-67. 2007....
- The effects of predator odors in mammalian prey species: a review of field and laboratory studiesRaimund Apfelbach
Tierphysiologie, Zoologisches Institut, Universitat Tubingen, Auf der Morgenstelle 28, D 72076 Tubingen, Germany
Neurosci Biobehav Rev 29:1123-44. 2005..Recent research is starting to uncover the neural circuitry activated by predator odors, leading to hypotheses about how such activation leads to observable effects on reproduction, foraging and feeding...
- (-)-Epigallocatechin-3-gallate prevents lipopolysaccharide-induced elevation of beta-amyloid generation and memory deficiencyYoung Kyoung Lee
College of Pharmacy, Chungbuk National University 12, Heungduk gu, Cheongju, Chungbuk 361 763, Republic of Korea
Brain Res 1250:164-74. 2009....
- Approach and avoidance learning in patients with major depression and healthy controls: relation to anhedoniaH W Chase
Behavioural and Clinical Neuroscience Institute, University of Cambridge, UK
Psychol Med 40:433-40. 2010....
- Impaired Pavlovian fear extinction is a common phenotype across genetic lineages of the 129 inbred mouse strainM Camp
Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, NIH, Bethesda, MD, USA
Genes Brain Behav 8:744-52. 2009..Taken together, these data show that impaired fear extinction is a phenotypic feature common across 129 substrains, and provide preliminary evidence that impaired fear extinction in 129S1 may reflect a pro-fear incubation-like process...
- Short- and long-term memory in Drosophila require cAMP signaling in distinct neuron typesAllison L Blum
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
Curr Biol 19:1341-50. 2009..At the neuroanatomical level, however, different temporal stages of memory can engage distinct neural circuits, a notion that has not been conceptually integrated with the cellular view...
- Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memoriesNiels Plath
Molecular Neurobiology, Department of Biology Chemistry Pharmacy, Freie Universitat Berlin, 14195 Berlin, Germany
Neuron 52:437-44. 2006..In addition, long-term depression is significantly impaired. Together, these results demonstrate a critical role for Arc/Arg3.1 in the consolidation of enduring synaptic plasticity and memory storage...
- Intracerebroventricular insulin enhances memory in a passive-avoidance taskC R Park
Interdisciplinary Program in Neurobiology and Behavior, University of Washington, Seattle, WA 98125, USA
Physiol Behav 68:509-14. 2000..This difference is consistent with an enhanced memory for the negative consequences of entering...
- Stimuli inevitably generated by behavior that avoids electric shock are inherently reinforcingJ A Dinsmoor
Department of Psychology, Indiana University, Bloomington 47405 7007, USA
J Exp Anal Behav 75:311-33. 2001....
- Changes in rat olfactory detection performance induced by orexin and leptin mimicking fasting and satiationA K Julliard
Laboratoire de Neurosciences Sensorielles, Comportement, Cognition, CNRS, UMR 5020, Universite de Lyon, Lyon 1, 50 avenue Tony Garnier, 69366 Lyon Cedex 07, France
Behav Brain Res 183:123-9. 2007..Orexin and leptin modulate the olfactory performance in a similar way as do physiological induced fasting and satiation and appear to be important factors in the interdependency of olfaction and food intake...
- Amyloid precursor protein knockout mice show age-dependent deficits in passive avoidance learningYann Senechal
Neuroscience Research, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Lichtstrasse 35, CH 4056 Basel, Switzerland
Behav Brain Res 186:126-32. 2008..The results suggest that APP and/or its proteolytic derivatives may play a role in long-term memory in adult brain and/or may be required during the development and maintenance of neuronal networks involved in this type of memory...
- Differential neuromodulation of acquisition and retrieval of avoidance learning by the lateral habenula and ventral tegmental areaJason Shumake
Leibniz Institute for Neurobiology, D 39118 Magdeburg, Germany
J Neurosci 30:5876-83. 2010..to the inhibition of dopaminergic neurons during loss of reward, as well as to deficits in escape and avoidance learning. We hypothesized that a dopamine signal might underlie the negative reinforcement of avoidance responses and ..
- The impact of selective amygdala, orbital frontal cortex, or hippocampal formation lesions on established social relationships in rhesus monkeys (Macaca mulatta)Christopher J Machado
Department of Neurobiology and Anatomy, University of Texas Health Science Center, TX, USA
Behav Neurosci 120:761-86. 2006..Interpretation of results in relation to cognitive processes mediated by each structure is discussed...
- The automatic evaluation of novel stimuliKimberly L Duckworth
Department of Psychology, New York University, New York 10003, USA
Psychol Sci 13:513-9. 2002..A final experiment revealed that exposure to novel stimuli produces muscular predispositions to approach or avoid them...
- Glucocorticoid enhancement of memory consolidation in the rat is blocked by muscarinic receptor antagonism in the basolateral amygdalaA E Power
Center for the Neurobiology of Learning and Memory, and Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
Eur J Neurosci 12:3481-7. 2000....
- Approach and avoidance in fear of spidersMike Rinck
Dresden University of Technology, Germany
J Behav Ther Exp Psychiatry 38:105-20. 2007..Moreover, compatibility effects predicted fear-related behavior independently of questionnaires. Potential applications, extensions, and limitations of the findings are discussed...
- Differential contributions of the basolateral and central nuclei of the amygdala in the negative affective component of chemical somatic and visceral pains in ratsSachi Tanimoto
Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606 8501, Japan
Eur J Neurosci 18:2343-50. 2003..Taken together, these results suggest that activation of distinct amygdaloid nuclei could differentially contribute to chemical somatic and visceral noxious stimuli-induced negative affective, but not sensory components of pains...
- A systems approach to the cellular analysis of associative learning in the pond snail LymnaeaP R Benjamin
Sussex Centre for Neuroscience, School of Biological Sciences, University of Sussex, Falmer, Brighton, East Sussex, BN1 9QG, UK
Learn Mem 7:124-31. 2000..Available information on the synaptic connectivity and transmitter content of identified neurons within the Lymnaea circuits will allow further work on the synaptic and molecular mechanisms of learning and memory...
- The effects of fear and anger facial expressions on approach- and avoidance-related behaviorsAbigail A Marsh
Department of Psychology, Harvard University, Cambridge, MA, USA
Emotion 5:119-24. 2005..Although the fear expression may signal that a threat is present in the environment, the effect of the expression on conspecifics may be in part to elicit approach...
- Differential involvement of the dorsal hippocampus in passive avoidance in C57bl/6J and DBA/2J micePetra J J Baarendse
Center for Neurogenomics and Cognitive Research and Institute for Neurosciences INW, Vrije Universiteit Amsterdam, The Netherlands
Hippocampus 18:11-9. 2008....
- Innate versus learned odour processing in the mouse olfactory bulbKo Kobayakawa
Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Tokyo 113 0032, Japan
Nature 450:503-8. 2007..These results indicate that, in mice, aversive information is received in the olfactory bulb by separate sets of glomeruli, those dedicated for innate and those for learned responses...
- Aversive reinforcement improves visual discrimination learning in free-flying honeybeesAurore Avarguès-Weber
Universite de Toulouse, UPS, Centre de Recherches sur la Cognition Animale, Toulouse, France
PLoS ONE 5:e15370. 2010..As we assumed that quinine acts as an aversive stimulus, we analyzed whether aversion, if any, is based on an aversive sensory input at the gustatory level or on a post-ingestional malaise following quinine feeding...
- An internal thermal sensor controlling temperature preference in DrosophilaFumika N Hamada
National Center for Behavioral Genomics, Volen Center for Complex Systems, Biology Department, Brandeis University MS 008, 415 South Street, Waltham, Massachusetts 02454, USA
Nature 454:217-20. 2008..This provides a potentially general strategy for robustly selecting a narrow temperature range optimal for survival...
- Individual differences in insular sensitivity during loss anticipation predict avoidance learningGregory R Samanez-Larkin
Department of Psychology, Stanford University, Stanford, CA 94305 2130, USA
Psychol Sci 19:320-3. 2008..These findings suggest that in addition to correlating with self-reported anxiety, heightened insular sensitivity may promote learning to avoid loss...
- The mouse light/dark box testMichel Bourin
Faculty of Medicine, EA 3256 Neurobiologie de l Anxiété et de la Dépression, Faculté de Médecine BP 53508, 44035 Nantes cedex 1, France
Eur J Pharmacol 463:55-65. 2003..g. serotonergic drugs or drugs acting on neuropeptide receptors) can be detected using this paradigm. It has the advantages of being quick and easy to use, without requiring the prior training of animals...
- The consolidation of new but not reactivated memory requires hippocampal C/EBPbetaS M Taubenfeld
Department of Neuroscience, Brown University, Providence, Rhode Island 02912, USA
Nat Neurosci 4:813-8. 2001..C/EBPbeta is an evolutionarily conserved genetic marker that has a selective role in the consolidation of new but not reactivated memories in the hippocampus...
- Differentiable contributions of human amygdalar subregions in the computations underlying reward and avoidance learningCharlotte Prévost
Trinity College Institute of Neuroscience and School of Psychology, Trinity College, Dublin, Ireland
Eur J Neurosci 34:134-45. 2011..subregions within the human amygdala during two different types of instrumental conditioning: reward and avoidance learning. Through the application of a computational-model-based analysis, we found evidence for a dissociation ..
- Actin polymerization-dependent increase in synaptic Arc/Arg3.1 expression in the amygdala is crucial for the expression of aversive memory associated with drug withdrawalYao Liu
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China
J Neurosci 32:12005-17. 2012..1 is a crucial mediator for actin polymerization functions, and, thus, underscores the unknown details of how actin polymerization mediates synaptic plasticity and memory...
- Mushroom body efferent neurons responsible for aversive olfactory memory retrieval in DrosophilaJulien Séjourné
Genes and Dynamics of Memory Systems, Neurobiology Unit, CNRS, Ecole Superieure de Physique et de Chimie Industrielles, Paris, France
Nat Neurosci 14:903-10. 2011..As the lateral horn has been implicated in innate responses to repellent odorants, we propose that MB-V2 neurons recruit the olfactory pathway involved in innate odor avoidance during memory retrieval...
- Uncompetitive NMDA receptor antagonists attenuate NMDA-induced impairment of passive avoidance learning and LTPW Zajaczkowski
Department of Pharmacology, Merz and Co, Frankfurt M, Germany
Neuropharmacology 36:961-71. 1997..Dark avoidance learning was impaired by systemic NMDA administration (starting at 25 mg/kg) that was not related to either toxic ..
- Onset and progression of behavioral and molecular phenotypes in a novel congenic R6/2 line exhibiting intergenerational CAG repeat stabilityRandi Michelle Cowin
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
PLoS ONE 6:e28409. 2011..Data from TR-FRET suggest an association of mutant protein state changes (soluble versus aggregated) in disease onset and progression...
- Effect of MK-801-induced impairment of inhibitory avoidance learning in zebrafish via inactivation of extracellular signal-regulated kinase (ERK) in telencephalonMing Chong Ng
Department of Life Science, National Taiwan Normal University, Taipei, Taiwan
Fish Physiol Biochem 38:1099-106. 2012..First, we established a new system to investigate the inhibitory avoidance learning of zebrafish where they were trained to refrain from swimming from a shallow compartment to a deep ..
- Human avoidance and approach learning: evidence for overlapping neural systems and experiential avoidance modulation of avoidance neurocircuitryMichael W Schlund
Department of Behavior Analysis, University of North Texas, Denton TX, PO Box 310919, Denton, TX 76203, USA
Behav Brain Res 225:437-48. 2011....
- Involvement of insulin-like peptide in long-term synaptic plasticity and long-term memory of the pond snail Lymnaea stagnalisJun Murakami
Laboratory of Functional Biology, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Sanuki 769 2193, Japan
J Neurosci 33:371-83. 2013..These data suggest that MIPs trigger changes in synaptic connectivity that may be correlated with the consolidation of taste aversion learning into CTA-LTM in the Lymnaea CNS...
- Progressive cognitive impairment and anxiety induction in the absence of plaque deposition in C57BL/6 inbred mice expressing transgenic amyloid precursor proteinKang Woo Lee
Department of Neuroscience, Ewha Institute of Neuroscience and Medical Research Institute, Ewha Womans University School of Medicine, Seoul, Korea
J Neurosci Res 76:572-80. 2004....
- The lateral habenula regulates defensive behaviors through changes in 5-HT-mediated neurotransmission in the dorsal periaqueductal gray matterRoger Luis Henschel Pobbe
Department of Pharmacology, School of Medicine, University of Sao Paulo, Av Bandeirantes, 3900, CEP 14049 900 Ribeirao Preto, Brazil
Neurosci Lett 479:87-91. 2010..While stimulation of 5-HT(1A) receptors selectively affects escape performance, 5-HT(2A/2C) receptors modulate both inhibitory avoidance and escape...
- Immunohistochemical estimation of brain choline acetyltransferase and somatostatin related to the impairment of avoidance learning induced by thiamine deficiencyO Nakagawasai
Department of Pharmacology, Tohoku Pharmaceutical University, Sendai, Japan
Brain Res Bull 52:189-96. 2000We have found that thiamine-deficient (TD) rats show significant impairment of avoidance learning on the 25th day after the start of TD diet, as measured by passive-avoidance task. Administration of physostigmine (0.1 mg/kg, i.p...
- Approach and avoidance learning in obsessive-compulsive disorderTanja Endrass
Humboldt Universitat zu Berlin, Institut fur Psychologie, Berlin, Germany
Depress Anxiety 28:166-72. 2011..The purpose of this study was to examine feedback-based learning and to investigate whether learning from positive and negative feedback is differentially altered in OCD...
- Regulation of nuclear factor kappaB in the hippocampus by group I metabotropic glutamate receptorsKenneth J O'Riordan
Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
J Neurosci 26:4870-9. 2006....
- Coordinated activity of ventral tegmental neurons adapts to appetitive and aversive learningYunbok Kim
Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania, United States America
PLoS ONE 7:e29766. 2012..These patterns also adapted when task contingencies were changed. Taken together, these data demonstrate that VTA neurons organize flexibly as functional networks to support appetitive and aversive learning...
- Sociality, pathogen avoidance, and the neuropeptides oxytocin and arginine vasopressinMartin Kavaliers
Department of Psychology, Social Science Centre, University of Western Ontario, London, Ontario, Canada N6A 5C1
Psychol Sci 22:1367-74. 2011..The evidence reviewed here suggests that OT and AVP likely play parallel roles in modulating the recognition and avoidance of socially relevant pathogen threat in both humans and rodents...
- Susceptibility of a potential animal model for pathological anxiety to chronic mild stressAmber R Salomons
Department of Animals in Science and Society, Division of Animal Welfare and Laboratory Animal Science, Utrecht University, Utrecht, The Netherlands
Behav Brain Res 209:241-8. 2010..These results support the hypothesis that 129P3/J mice might be an interesting model for pathological anxiety...
- Glutamatergic activation of anterior cingulate cortex mediates the affective component of visceral pain memory in ratsNi Yan
Neuroscience Research Laboratory, Department of Biology and Chemistry, City University of Hong Kong, Hong Kong, China
Neurobiol Learn Mem 97:156-64. 2012..pACC activation is critical for the memory processing involved in long-term negative affective state and prediction of aversive stimuli by contextual cue...
- 2,3,5-Trimethyl-3-thiazoline (TMT), a component of fox odor - just repugnant or really fear-inducing?Markus Fendt
Animal Physiology, University of Tubingen, Auf der Morgenstelle 28 D 72076 Tübingen, Germany
Neurosci Biobehav Rev 32:1259-66. 2008..Therefore, TMT is still a viable alternative stimulus to natural predator odors to investigate effects of predator odors on behavior...
- Retraining automatic action-tendencies to approach alcohol in hazardous drinkersReinout W Wiers
University of Amsterdam, Department of Psychology, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
Addiction 105:279-87. 2010..The main aim of this study was to test whether automatic action-tendencies to approach alcohol can be modified, and whether this affects drinking behaviour...
- Behavioral and electrophysiological studies of chronic oral administration of L-type calcium channel blocker verapamil on learning and memory in ratsReza Lashgari
Neuroscience Research Center and Department of Physiology, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
Behav Brain Res 171:324-8. 2006..and orally at different doses (10, 20 and 50 mg/kg) was used to investigate learning and memory by passive avoidance learning. LTP in perforant-DG synapses was assessed (by either 200 or 400 Hz tetanization) in order to investigate ..
- A temporal difference account of avoidance learningMichael Moutoussis
Tolworth Hospital, Surbiton, England
Network 19:137-60. 2008..The model accounts for normal conditioned avoidance learning, the persistence of responding in extinction, and critical effects of dopamine blockade, notably that ..
- Interhippocampal transfer in passive avoidance task modifies metabolic activity in limbic structuresJ M Cimadevilla
Department of Neuroscience, University of Almeria, Carretera de Sacramento s n, Almeria, Spain
Hippocampus 21:48-55. 2011..By combining behavioral tasks and cytochrome oxidase histochemistry we demonstrated that several brain structures, including the hippocampus, amygdala and other related regions, change their activity under the above-mentioned treatments...
- Neuronal cell adhesion molecule deletion induces a cognitive and behavioral phenotype reflective of impulsivityL D Matzel
Department of Psychology, Program in Behavioural Neuroscience, Rutgers University, Piscataway, NJ 08854, USA
Genes Brain Behav 7:470-80. 2008....
- Avoidance motivation and choking under pressure in soccer penalty shootoutsGeir Jordet
Department of coaching and psychology, Norwegian School of Sport Sciences, Oslo, Norway
J Sport Exerc Psychol 30:450-7. 2008..Thus, avoidance motivation may help explain why professional athletes occasionally choke under pressure...
- Predator odor-induced conditioned fear involves the basolateral and medial amygdalaLorey K Takahashi
Department of Psychology, University of Hawaii at Manoa, Manoa, HI, USA
Behav Neurosci 121:100-10. 2007....
- Scopolamine-induced learning impairment reversed by physostigmine in zebrafishYeon Hwa Kim
Department of Biological Sciences, Institute of Molecular and Cellular Biology, Inha University, 253 Yong Hyun Dong, Nam Gu, Incheon 402 751, Republic of Korea
Neurosci Res 67:156-61. 2010..These results show that scopolamine impairs both the acquisition of passive avoidance response and retention of the learned response, and that physostigmine rescues the amnesic effects of scopolamine in zebrafish...
- The anxiolytic and analgesic properties of fenobam, a potent mGlu5 receptor antagonist, in relation to the impairment of learningWolfgang Jacob
In Vivo Pharmacology, Merz Pharmaceuticals GmbH, Frankfurt am Main, Germany
Neuropharmacology 57:97-108. 2009..Our results indicate that the beneficial effects of fenobam occur in a similar dose range as the potential side-effects...
- Corticohippocampal contributions to spatial and contextual learningRebecca D Burwell
Department of Psychology, Brown University, Providence, Rhode Island 02912, USA
J Neurosci 24:3826-36. 2004..The evidence that different brain systems underlie spatial navigation and contextual learning has implications for research on memory when parahippocampal regions are involved...
- Different temporal profiles of amnesia after intra-hippocampus and intra-amygdala infusions of anisomycinClinton E Canal
Neuroscience Program, University of Illinois, 603 East Daniel Street, Champaign, IL 61820, USA
Behav Neurosci 121:732-41. 2007..The distinct temporal properties for amnesia following anisomycin injections into the hippocampus or amygdala may reflect different consequences for memory of perturbations of the neural system in which the manipulation is made...
- Inhibition of protein kinase A activity during conditioned taste aversion retrieval: interference with extinction or reconsolidation of a memory?Ming Teng Koh
Department of Psychology, University of Washington, Seattle, WA 98195 1525, USA
Neuroreport 14:405-7. 2003..Results confirm recent findings that stored memories become more labile when they are retrieved and extend these findings to CTA memories...
- Response of Drosophila to wasabi is mediated by painless, the fly homolog of mammalian TRPA1/ANKTM1Bader Al-Anzi
Division of Biology 156 29, California Institute of Technology, Pasadena, California 91125, USA
Curr Biol 16:1034-40. 2006..Our results suggest that the stinging sensation of isothiocyanate is caused by activation of an evolutionarily conserved molecular pathway that is also used for nociception...
- Odour avoidance learning in the larva of Drosophila melanogasterSukant Khurana
Tata Institute of Fundamental Research, National Centre for Biological Sciences, Bangalore 560 065, India
J Biosci 34:621-31. 2009..The same method of analysis when applied to learning mutants dunce, amnesiac, rutabaga and radish reveals memory deficits characteristic of the mutant strains...
- Involvement of actin rearrangements within the amygdala and the dorsal hippocampus in aversive memories of drug withdrawal in acute morphine-dependent ratsYuan yuan Hou
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
J Neurosci 29:12244-54. 2009....
- Uncertainty during anticipation modulates neural responses to aversion in human insula and amygdalaI Sarinopoulos
Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
Cereb Cortex 20:929-40. 2010..Findings provide the first evidence of the brain mechanisms of covariation bias and highlight the temporal dynamics of ACC, insula, and amygdala recruitment for processing aversion in the context of uncertainty...
- The L-Type voltage-gated calcium channel Cav1.3 mediates consolidation, but not extinction, of contextually conditioned fear in miceBrandon C McKinney
Medical Scientist Training Program, University of Michigan, Ann Arbor, Michigan 48109, USA
Learn Mem 13:584-9. 2006..3 knockout mice is not likely the result of an inability to encode the context, but may reflect an inability to make the association between the context and the unconditioned stimulus...
- Effects of histamine and cholinergic systems on memory retention of passive avoidance learning in ratsMaryam Eidi
Department of Biology, Sciences and Research Campus, Azad University, Tehran, Iran
Eur J Pharmacol 465:91-6. 2003..It is concluded that histaminergic and cholinergic systems have opposing effects on memory retention. Also, the histaminergic system elicits an interaction with the cholinergic system in memory retention...
- Enhanced inhibitory avoidance learning prevents the long-term memory-impairing effects of cycloheximide, a protein synthesis inhibitorArnulfo Díaz-Trujillo
Departamento de Neurobiologia Conductual y Cognitiva, Instituto de Neurobiologia, Universidad Nacional Autonoma de Mexico, Campus Juriquilla, Queretaro 76230, Mexico
Neurobiol Learn Mem 91:310-4. 2009....
- The role of muscarinic and nicotinic cholinergic neurotransmission in aversive conditioning: comparing pavlovian fear conditioning and inhibitory avoidanceMatthew R Tinsley
Department of Psychology, University of California, Los Angeles, California 90095, USA
Learn Mem 11:35-42. 2004
- Retrieval does not induce reconsolidation of inhibitory avoidance memoryMartin Cammarota
Memory Research Laboratory, Institute for Cell Biology and Neuroscience Prof Dr Eduardo de Robertis, School of Medicine, University of Buenos Aires, Ciudad Autonoma de Buenos Aires, CP 1121, Argentina
Learn Mem 11:572-8. 2004..Hence, our results indicate that there is no retrieval-induced, protein synthesis-dependent process that would cause reconsolidation of IA memory...
- Involvement of the rostral anterior cingulate cortex in consolidation of inhibitory avoidance memory: interaction with the basolateral amygdalaEmily L Malin
Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
Neurobiol Learn Mem 87:295-302. 2007....
- Mild hypoxia preconditioning prevents impairment of passive avoidance learning and suppression of brain NGFI-A expression induced by severe hypoxiaElena Rybnikova
Laboratory of Neuroendocrinology, Pavlov Institute of Physiology Russian Academy of Sciences, 199034 St Petersburg, Russia
Behav Brain Res 160:107-14. 2005..The preconditioning up-regulated severe hypoxia-suppressed neocortical and hippocampal expression of NGFI-A, suggesting a possible role for NGFI-A in the neuroprotective mechanisms activated by hypoxic preconditioning...
- Functions of Associative Auditory Cortical PlasticityNorman M Weinberger; Fiscal Year: 2013..auditory memory should increase the level of memory strength, retention of acoustic details and facilitate avoidance learning. The findings have direct translational implications for the design and implementation of therapeutic ..
- The role of medial prefrontal cortex in active avoidance behaviorJustin M Moscarello; Fiscal Year: 2013..Signaled active avoidance learning can offer important insights into this transitional process...
- Acquisition and Expression of Avoidance: Computational Modeling and Human StudiesCatherine E Myers; Fiscal Year: 2013..There is a rich tradition of studying avoidance learning in animals, including work from our lab and others, but work directly linking animal data to human avoidance ..
- Emotional Reactivity and Capacity for Emotional Control in Psychopathic IndividuaMatthew Shane; Fiscal Year: 2011..g. fear, anxiety) at levels sufficient to mediate behavioral control or motivate avoidance learning. While a consistent literature has indeed confirmed that psychopaths show reduced reactivity to aversive ..
- Neural mechanisms of avoidance learning and active coping via emotion regulationMauricio R Delgado; Fiscal Year: 2013..g., Salamone, 1994;LeDoux &Gorman, 2001). Yet, less is known about 1) human mechanisms of avoidance learning;2) alternative means of coping with negative affect that are dependent on higher-order cognition and control ..
- Neural mechanisms of extinction-resistant avoidance behaviorKevin D Beck; Fiscal Year: 2013..basic science research program is developing an animal model for understanding the role of vulnerability in avoidance learning. Inbred Wistar-Kyoto rats are stress sensitive and acquire active avoidance response faster and to a higher ..
- Learning to avoid pain: Computational mechanisms and application to methamphetamiTOR DESSART WAGER; Fiscal Year: 2013..combination of two successful research traditions is a powerful approach that can provide new measures of avoidance learning in healthy individuals and drug abusers and links with animal models of addiction...
- Neural Correlates of Avoidance Learning in Substance AbuseJody L Tanabe; Fiscal Year: 2013..Aim 2. Determine the neural pathways involved in negative and positive reinforcement learning Aim 3. Determine if frontal-limbic activity differs in SDI compared to controls during negative and positive reinforcement learning ..
- CONDITIONAL DISCRIMINATION LEARNINGThomas Zentall; Fiscal Year: 1980..conditional discrimination learning may involve not only A-B, and C-D approach learning but also, A-D, C-B avoidance learning and (2) similarity (identity) between the sample stimuli (A and C) and the comparison stimuli (B and D) can ..
- Apparatus for Testing Pain Sensitivity in RodentsCharles Gibbs; Fiscal Year: 2003..The ability to change floor temperature rapidly allows for repeated trials with minimal avoidance learning. Each chamber will be able to produce an aversive, non-painful condition, using bright light...
- SOD/Catalase mimics for age-related learning impairmentMichel Baudry; Fiscal Year: 2001..They will be tested for acquisition and retention of 2 different tasks, an avoidance learning paradigm, and a fear-conditioning paradigm...
- HIPPOCAMPAL FUNCTION AFTER PRENATAL ETHANOL EXPOSUREH Swartzwelder; Fiscal Year: 1990..This latter process will be correlated with passive avoidance learning. Our goals are 1) to demonstrate and describe the functional impact of prenatal ethanol exposure on the ..
- NICOTINE ADDICTION IN MICE LACKING THE NEURONAL NACHRMARINA PICCIOTTO; Fiscal Year: 2009..We have identified hypersensitive passive avoidance learning as a long-lasting behavioral outcome of altering nicotinic acetylcholine receptor (nAChR) function during ..
- REWARD SHIFTS ENHANCE TOXIN AVOIDANCE AND NEOPHOBIABRUCE LOMBARDI; Fiscal Year: 1980..of the present research will be twofold, first to explore the mechanism by which reward shifts facilitate poison avoidance learning, and second to examine the effects of neophobia produced by shifts in reward on investigatory behavior.
- MOLECULAR MECHANISMS OF CONDITIONED TASTE AVERSIONTHOMAS HOUPT; Fiscal Year: 2004..These experiments will contribute to an understanding of the neural pathways and molecular mechanisms underlying changes in food preferences that occur in eating disorders such as obesity and anorexia nervosa. ..
- Behavioral and Neural Effects of High Magnetic FieldsTHOMAS HOUPT; Fiscal Year: 2009..Secondly, vestibular dysfunction is a common complaint and cause of injury (e.g. falling in the elderly), and this proposal contains novel approaches to investigating the inner ear and vestibular system ..
- Mechanisms Underlying the Cognitive Function of SleepSubimal Datta; Fiscal Year: 2009....
- Antipsychotic Drugs and Maternal Behavior: A Preclinical InvestigationMing Li; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Emotional Mechanisms /Blood-Injection-Injury PhobiaOlubunmi Olatunji; Fiscal Year: 2004..This research will provide an important contribution to the understanding of the emotions that mediate BII phobia, thus potentially providing a foundation for incorporating effective treatment strategies. ..
- The Role of the Amygdala in Anesthetic-Induced AmnesiaMICHAEL ALKIRE; Fiscal Year: 2006..Understanding anesthesia requires understanding both phenomenon. We recently demonstrated, using inhibitory avoidance learning in rats, that the basolateral amygdala (BL) is critically nvolved with mediating the amnesic effects of ..
- Neuroanatomy of Anticipation in Anxiety DisordersJack Nitschke; Fiscal Year: 2009..g., anticipation that results in adaptive response) as well as understanding how dysfunction in this system occurs. ..
- Rapid DA-Acb signaling in ingestive behaviorsMITCHELL ROITMAN; Fiscal Year: 2008..These studies will establish the range of natural stimuli that promote rapid DA-Acb signaling - setting the foundation for examining aberrant signaling underlying drug addiction. [unreadable] [unreadable] [unreadable] [unreadable]..
- Temperament and Developmental PsychopathologyDavid Rettew; Fiscal Year: 2008..abstract_text> ..
- Mechanisms of Neural Mobilization for Chronic PainSTEVEN GEORGE; Fiscal Year: 2007..These data may also provide support for a future clinical trial investigating the efficacy of median nerve NMT for patients with CTS. [unreadable] [unreadable] [unreadable]..
- Behavioral Interventions for Low Back PainSTEVEN GEORGE; Fiscal Year: 2007....
- Predictors of Drug Related Attentional Biases among Crack/Cocaine Users with PTSDMATTHEW TULL; Fiscal Year: 2007..Consequently, this study will have tremendous public health benefits. [unreadable] [unreadable] [unreadable]..
- IMPROVING CARE OF PANIC DISORDER IN PRIMARY CAREMichelle Craske; Fiscal Year: 2002..abstract_text> ..
- Functional Neuroimaging in Anxiety and FearJack Nitschke; Fiscal Year: 2006..abstract_text> ..
- Taste Coding by Neural Circuitry in the Brain StemPATRICIA DI LORENZO; Fiscal Year: 2005..By describing the taste responsivity of inputs and outputs of NTS cells, data from this project will help provide an understanding of information processing in the NTS. ..
- General Cognitive /Learning Deficits in Aged MiceLOUIS MATZEL; Fiscal Year: 2003..These studies are a critical prelude to future work directed at the elucidation of the brain substrates for age-related declines in general cognitive/learning abilities. ..
- Markers of Risk for Anxiety DisordersMichelle Craske; Fiscal Year: 2003..Measurement of eye gaze in youths to gauge ongoing conditioning and attentional processes represents a new methodology. ..
- Ribonucleotide monophosphates and umami tasteEugene Delay; Fiscal Year: 2003..If IMP and GMP have identical taste qualities, and these qualities are the same as MSG and the other "umami" substance. ..
- L-amino and acid taste in mice.Eugene Delay; Fiscal Year: 2005..g., diabetics, cardiovascular disease, aged). ..
- Ethanol & Anxiety: Cellular MechanismsBRIAN MCCOOL; Fiscal Year: 2008..These studies could therefore provide insight into the cellular mechanisms governing anxietyassociated relapse in human alcoholics. ..
- PREVENTING CHRONIC WHIPLASH PAIN: BIOBEHAVIORAL APPROACHDENNIS TURK; Fiscal Year: 2005..The data from this trial will provide important information about the potential of early interventions to prevent chronic problems that afflict millions of MVA victims. ..
- THC Affects the Development of Executive FunctionDiana Dow Edwards; Fiscal Year: 2008..abstract_text> ..
- NEURAL MEDIATION OF CONDITIONED TASTE AVERSIONSILENE BERNSTEIN; Fiscal Year: 2004....
- FAMILY CONFLICT AND DECISION MAKING FOR ADVANCED CANCERLaura Siminoff; Fiscal Year: 2004..Cut-off scores will be provided for classifying concordant and discordant families. In addition, rich and detailed descriptive information about the family treatment decision-making process will be provided. ..
- Involvement of mGluR5 in inhibitory avoidance and agingAgnes Simonyi; Fiscal Year: 2004..The proposed research seeks to identify the mGluR subtype required for memory formation in passive avoidance learning. Selective mGluR antagonists will be infused into the hippocampus after training the rats in a one-trial ..
- Effort-related Functions of Nucleus Accumbens Adenosine A2A ReceptorsJohn D Salamone; Fiscal Year: 2010....
- Behavioral Pharmacology of Serotonin Inverse AgoinstsEllen Walker; Fiscal Year: 2006..Taken together, these experiments will provide a novel pharmacological and/or behavioral profile for 5-HT2C inverse agonists and neutral antagonists while testing hypotheses generated from in vitro data. ..
- Neuroscience at the Boundaries of Neurology and PsychiatryNeal Swerdlow; Fiscal Year: 2006..unreadable] [unreadable]..
- QUALITY OF LIFE IN ADULT CANCER SURVIVORSCharles Carver; Fiscal Year: 2002..These people can continue providing important information about the experience of cancer survivorship and what qualities make the process easier or harder. ..
- LEAD: ATTENTION, IMPULSIVITY, AND DOPAMINESTEPHEN KIEFER; Fiscal Year: 2002..abstract_text> ..
- PUBLIC ATTITUDES TOWARDS DEATH AND ORGAN PROCUREMENTLaura Siminoff; Fiscal Year: 2001..Finally, a community dialogue will be implemented to interpret and disseminate the findings and provide recommendations to policy makers. ..
- PERIPHERAL GUSTATORY PROCESSINGMARION ELIZABETH FRANK; Fiscal Year: 2010..Also, elimination of taste disorders would improve the quality of life that depends on enjoyment of food and drink, a universal human need contributing much to human sociality. ..
- MOLECULAR ANALYSIS OF OLFACTORY SIGNALINGCornelia Bargmann; Fiscal Year: 2008..Characterizing these signaling pathways may elucidate related pathways that are important in disease and injury states. ..
- Linking Affect to Action: Critical Contributions of the Orbitofrontal CortexGeoffrey Schoenbaum; Fiscal Year: 2006..The participation of minorities and women has been emphasized at each level (organizers, speakers, students). Thus the conference will address important scientific, social, and educational issues. [unreadable] [unreadable] [unreadable]..
- Society for the Stimulus Properties of Drugs SatelliteEllen Walker; Fiscal Year: 2005..The SSPD Satellite to the EBPS 2005 Conference promises to coordinate, exchange, and disseminate information to further our understanding of drug abuse. ..
- Associatively-activated event representationsPeter Holland; Fiscal Year: 2006..The proposed research provides a basis for the understanding of basic processing of imaginal events in associative learning. ..
- Anxiety and Psychological Vulnerability in Chest PainKAMILA WHITE; Fiscal Year: 2005..Data from this research program will allow Dr. White to establish an empirical foundation from which to apply these data to the development of novel interventions for patients with NCCP. ..
- Cellular bases of noncoincidence learning in HermissendaJoseph Farley; Fiscal Year: 2007..Ratiometric fura-2 imaging methods will be used to see if the interstimulus intervals that result in successful EU-conditioning match a specific [Ca2+]i level. ..
- Bupropion and Secondary Motivational Effects of NicotineANTHONY RAUHUT; Fiscal Year: 2005..S. population to 12% and 16%, accordingly. ..
- Novel Operant Thermal Assessments of Orofacial PainJOHN NEUBERT; Fiscal Year: 2007..unreadable] [unreadable]..
- Cellular and Molecular Mechanisms of Learning in the ZebrafishDavid Glanzman; Fiscal Year: 2007..Such an understanding will facilitate the development of treatments for Alzheimer's disease and other disorders of memory. [unreadable] [unreadable] [unreadable]..
- Cognitive Processing in Human Infants and PrimatesJustin Wood; Fiscal Year: 2007....
- LEARNING AND REPRODUCTIVE BEHAVIORMichael Domjan; Fiscal Year: 2005..The research will further our understanding of Pavlovian learning and will integrate the functional approach of ethologists with the emphasis on learning mechanisms in traditional studies of associative learning. ..
- Striatal Acetylcholine and Behavioral FlexibilityMICHAEL RAGOZZINO; Fiscal Year: 2005....
- Cue dependency with intravenous nutrients and nicotineNeil Rowland; Fiscal Year: 2007..These studies may help to develop ways in conditioned preferences can be manipulated to prevent or treat certain addictive disorders, including overeating. [unreadable] [unreadable] [unreadable]..
- Neural Substrates of Goal-Directed Learning in the Human BrainJOHN O DOHERTY; Fiscal Year: 2007..This research could ultimately be relevant in developing treatments for such conditions in which habitized or compulsive behaviors are returned to goal-directed control. [unreadable] [unreadable] [unreadable]..
- Attentional Regulation of Plasticity in Auditory CortexDaniel Polley; Fiscal Year: 2004..abstract_text> ..
- Time's Eye: Aging and Attention to Emotional StimuliDerek Isaacowitz; Fiscal Year: 2003..The results would also have implications for the etiology and treatment of depression. ..
- Health Status, Age, and Emotion RegulationSusan Charles; Fiscal Year: 2009....
- Structure and Assessment of Symptoms of DepressionDavid Watson; Fiscal Year: 2007..g., adolescents, pregnant and postpartum women, and older adults) and to modify the instrument as necessary for use with these populations. ..
- Substituted Amphetamines: NO-Dependent MechanismsYossef Itzhak; Fiscal Year: 2005....