vasculogenic impotence

Summary

Summary: Impotence caused by a diminution of blood flow to the penis. Arteries involved can be the terminal aorta, hypogastric, pudendal, penile, and cavernous arteries. Ectopic drainage of the corpora cavernosa via large superficial dorsal veins or abnormally large cavernous and crural veins can cause venogenic impotence. (From Walsh, et al., Campbell's Urology, 6th ed, p720). The expression "venous leakage" is seen often in international literature. Leakage refers to the failure of the blood to reach the penile erectile tissues.

Top Publications

  1. ncbi Vasculogenic impotence. Arterial and venous surgery
    D S Rao
    Department of Surgery, Division of Urology, Duke University Medical Center, Durham, North Carolina, USA
    Urol Clin North Am 28:309-19. 2001
  2. ncbi Testosterone undecanoate restores erectile function in a subset of patients with venous leakage: a series of case reports
    Aksam A Yassin
    Clinic of Urology Andrology, Segeberger Kliniken, Norderstedt Hamburg, Germany
    J Sex Med 3:727-35. 2006
  3. ncbi Corpus cavernosum from men with vasculogenic impotence is partially resistant to adenosine relaxation due to endothelial A(2B) receptor dysfunction
    Miguel Faria
    Laboratorio de Farmacologia, Instituto de Ciencias Biomedicas de Abel Salazar, Universidade do Porto, L Prof Abel Salazar 2, 4099 003 Porto, Portugal
    J Pharmacol Exp Ther 319:405-13. 2006
  4. ncbi Effect of hypothyroidism on the NO/cGMP pathway of corpus cavernosum in rabbits
    Hakan Kilicarslan
    Department of Urology, Faculty of Medicine, Uludag University, Bursa, Turkey
    J Sex Med 3:830-7. 2006
  5. ncbi Evaluation of penile revascularization for erectile dysfunction: a 10-year follow-up
    Y Vardi
    Department of Neuro Urology, Rambam Medical Center, Haifa, Israel
    Int J Impot Res 16:181-6. 2004
  6. ncbi Incidentally diagnosed Peyronie's disease in men presenting with erectile dysfunction
    A Kadioglu
    Section of Andrology, Department of Urology, Medical Faculty of Istanbul, University of Istanbul, Istanbul, Turkey
    Int J Impot Res 16:540-3. 2004
  7. ncbi Penile blunt trauma induced veno-occlusive erectile dysfunction
    C W Tsao
    National Defense Medical Center, National Defense University, Taipei, Taiwan, ROC
    Arch Androl 50:151-4. 2004
  8. ncbi [Investigation of diabetic men with erectile dysfunction to determine coronary flow reserve (CFR) and cardiac risk under medication with sildenafil (Viagra)]
    W Merkle
    Fachbereiche Urologie, Kardiologie und Diabetologie, Stiftung Deutsche Klinik für Diagnostik GmbH, Wiesbaden
    Aktuelle Urol 35:222-7. 2004
  9. ncbi Phentolamine re-dosing during penile dynamic colour Doppler ultrasound: a practical method to abolish a false diagnosis of venous leakage in patients with erectile dysfunction
    P Gontero
    Departments of Urology and Radiology, King s College Hospital, Denmark Hill, London SE5 9RS, UK
    Br J Radiol 77:922-6. 2004
  10. ncbi Plasma transforming growth factor-beta1 levels in patients with erectile dysfunction
    Ji Kan Ryu
    Department of Urology, Inha University School of Medicine, Incheon, Korea
    Asian J Androl 6:349-53. 2004

Research Grants

  1. MOLECULAR MECHANISMS OF CORPUS CAVERNOSUM FIBROSIS
    Robert Moreland; Fiscal Year: 1999
  2. TREATMENT AND PREVENTION OF IMPOTENCE
    Tom Lue; Fiscal Year: 1990
  3. FEMALE SEXUAL AROUSAL: CLITORAL AND VAGINAL PHYSIOLOGY
    Abdulmaged Traish; Fiscal Year: 2003
  4. FEMALE SEXUAL AROUSAL: CLITORAL AND VAGINAL PHYSIOLOGY
    Abdulmaged Traish; Fiscal Year: 2002
  5. FEMALE SEXUAL AROUSAL: CLITORAL AND VAGINAL PHYSIOLOGY
    Abdulmaged Traish; Fiscal Year: 2001
  6. FEMALE SEXUAL AROUSAL: CLITORAL AND VAGINAL PHYSIOLOGY
    Abdulmaged Traish; Fiscal Year: 2000
  7. Racial/Ethnic Disparities in Fall Risk and Bone Strength Among Men
    ANDRE ARAUJO; Fiscal Year: 2009
  8. Volume-Outcomes in Incontinence Surgery
    Jennifer Anger; Fiscal Year: 2005
  9. ERECTILE DYSFUNCTION AND NITRIC OXIDE SYNTHASE IN AGING
    Nestor Gonzalez Cadavid; Fiscal Year: 2006
  10. Mesenchymal Stem Cells for Myocardial Infarction
    Robert Kloner; Fiscal Year: 2006

Detail Information

Publications125 found, 100 shown here

  1. ncbi Vasculogenic impotence. Arterial and venous surgery
    D S Rao
    Department of Surgery, Division of Urology, Duke University Medical Center, Durham, North Carolina, USA
    Urol Clin North Am 28:309-19. 2001
    ..Further studies are likely to refine patient selection but are unlikely to expand the therapeutic use of these procedures...
  2. ncbi Testosterone undecanoate restores erectile function in a subset of patients with venous leakage: a series of case reports
    Aksam A Yassin
    Clinic of Urology Andrology, Segeberger Kliniken, Norderstedt Hamburg, Germany
    J Sex Med 3:727-35. 2006
    ..However, there are limited research and data supporting this association in humans...
  3. ncbi Corpus cavernosum from men with vasculogenic impotence is partially resistant to adenosine relaxation due to endothelial A(2B) receptor dysfunction
    Miguel Faria
    Laboratorio de Farmacologia, Instituto de Ciencias Biomedicas de Abel Salazar, Universidade do Porto, L Prof Abel Salazar 2, 4099 003 Porto, Portugal
    J Pharmacol Exp Ther 319:405-13. 2006
    ..Endothelial dysfunction may be correlated with a loss of adenosine A(2B) receptor activity in penile vessels from men with vasculogenic ED...
  4. ncbi Effect of hypothyroidism on the NO/cGMP pathway of corpus cavernosum in rabbits
    Hakan Kilicarslan
    Department of Urology, Faculty of Medicine, Uludag University, Bursa, Turkey
    J Sex Med 3:830-7. 2006
    ..Hypothyroidism has been reported to occur in 6% of impotent men. There is some evidence suggesting that hypothyroidism may be a cause of impotence...
  5. ncbi Evaluation of penile revascularization for erectile dysfunction: a 10-year follow-up
    Y Vardi
    Department of Neuro Urology, Rambam Medical Center, Haifa, Israel
    Int J Impot Res 16:181-6. 2004
    ..We found that the cure rate of this procedure is maintained and long-term follow-up shows good results, especially in the young nonsmokers...
  6. ncbi Incidentally diagnosed Peyronie's disease in men presenting with erectile dysfunction
    A Kadioglu
    Section of Andrology, Department of Urology, Medical Faculty of Istanbul, University of Istanbul, Istanbul, Turkey
    Int J Impot Res 16:540-3. 2004
    ..Our data indicate that one should always consider the possibility of PD in older patients with diabetes, presenting with only ED...
  7. ncbi Penile blunt trauma induced veno-occlusive erectile dysfunction
    C W Tsao
    National Defense Medical Center, National Defense University, Taipei, Taiwan, ROC
    Arch Androl 50:151-4. 2004
    ..Penile venous ligation, especially on the site-specific veins, is still the choice of treatment for the trauma-induced penile veno-occlusive erectile dysfunction, and the result is satisfactory...
  8. ncbi [Investigation of diabetic men with erectile dysfunction to determine coronary flow reserve (CFR) and cardiac risk under medication with sildenafil (Viagra)]
    W Merkle
    Fachbereiche Urologie, Kardiologie und Diabetologie, Stiftung Deutsche Klinik für Diagnostik GmbH, Wiesbaden
    Aktuelle Urol 35:222-7. 2004
    ....
  9. ncbi Phentolamine re-dosing during penile dynamic colour Doppler ultrasound: a practical method to abolish a false diagnosis of venous leakage in patients with erectile dysfunction
    P Gontero
    Departments of Urology and Radiology, King s College Hospital, Denmark Hill, London SE5 9RS, UK
    Br J Radiol 77:922-6. 2004
    ..It is essential to ensure cavernosal relaxation using phentolamine before a Doppler US diagnosis of venous leak is made. This two-stage assessment will allow this to be done efficiently and with a low risk of priapism...
  10. ncbi Plasma transforming growth factor-beta1 levels in patients with erectile dysfunction
    Ji Kan Ryu
    Department of Urology, Inha University School of Medicine, Incheon, Korea
    Asian J Androl 6:349-53. 2004
    ..To evaluate the plasma TGF-beta1 level in erectile dysfunction (ED) patients of various causes...
  11. ncbi Anatomic variations of cavernous arteries and their effect on measurement of hemodynamic parameters: a power Doppler study
    Hideo Sakamoto
    Department of Urology, Showa University School of Medicine, Tokyo, Japan
    Urology 63:539-44. 2004
    ..To assess the cavernous arterial (CA) anatomy with power Doppler imaging and evaluate the effects of any anatomic variations on the measurement of hemodynamic parameters...
  12. ncbi Effect of hypothyroidism on the nitrergic relaxant responses of corpus cavernosal smooth muscle in rabbits
    Bulent Sarac
    Department of Pharmacology, School of Medicine, Cumhuriyet University, Silvas, Turkey
    Int J Urol 13:58-63. 2006
    ..However, several recent studies have reported evidence of hormonal abnormalities in 25-35% of impotent men. Hypothyroidism has been reported to occur in 6% of impotent men...
  13. ncbi Enhanced external counterpulsation in patients with coronary artery disease-associated erectile dysfunction. Part II: impact of disease duration and treatment courses
    Ahmed I El-Sakka
    Department of Urology, Suez Canal University, Ismailia, Egypt
    J Sex Med 4:1448-53. 2007
    ..Recent results have demonstrated a positive impact of EECP on patients with ischemic heart disease (IHD)-associated erectile dysfunction (ED)...
  14. ncbi Diabetes impairs endothelium-dependent relaxation of human penile vascular tissues mediated by NO and EDHF
    Javier Angulo
    Fundación para la Investigación y el Desarrollo en Andrología 28304, Madrid, Spain
    Biochem Biophys Res Commun 312:1202-8. 2003
    ....
  15. ncbi Physiological regulation of penile arteries and veins
    D Prieto
    Departamento de Fisiologia, Facultad de Farmacia, Universidad Complutense de Madrid, Madrid, Spain
    Int J Impot Res 20:17-29. 2008
    ..In addition, only few studies have investigated the changes in structure and function of penile arteries in cardiovascular risk situations leading to ED...
  16. ncbi [Erectile dysfunction--value of neurophysiologic diagnostic procedures]
    M J Hilz
    Neurologische Klinik der Universität Erlangen Nürnberg
    Urologe A 42:1345-50. 2003
    ..In addition, the assessment of heart rate variability at rest, during metronomic breathing, Valsalva maneuver, and active standing might be helpful to identify an autonomic neuropathy as the cause of erectile dysfunction...
  17. ncbi [Surgical therapy of erectile dysfunction. Current status]
    F J Martinez Portillo
    Klinik und Poliklinik fur Urologie, Universität Schleswig Holstein, Campus Kiel
    Urologe A 42:1337-44. 2003
    ..There are convincing long-term results with a high degree of patient and partner satisfaction, high patient acceptance and a good functional durability of the mostly three-part hydraulic implants...
  18. ncbi [Diagnosis of erectile dysfunction--what is still needed today?]
    W H Weiske
    Stuttgart
    Urologe A 42:1317-21. 2003
    ..Invasive testing for ED has decreased due to the high responder rate for oral PDE-5 inhibitors...
  19. ncbi Functional and morphological improvement in erectile tissue of hypertensive rats by long-term combined therapy with phosphodiesterase type 5 inhibitor and losartan
    Jorge Eduardo Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires
    J Sex Med 4:1291-303. 2007
    ..Phosphodiesterase type 5 (PDE5) inhibitors and angiotensin II receptor blockers (ARB) are both common and efficient therapy in patients with ED and arterial hypertension, respectively...
  20. ncbi The progression of the penile vein: could it be recurrent?
    Shyh Chyan Chen
    Microsurgical Potency Reconstruction and Research Center, Taiwan Adventist Hospital, 424 Pa Te Road, Sec 2, Taipei 105, Taiwan, ROC
    J Androl 26:53-60. 2005
    ..We therefore believe that the clinical recurrence may not be due to venous regeneration, and penile venous surgery, if properly performed, may be durable, although larger studies will be required...
  21. ncbi A three-dimensional model of the penis for analysis of tissue stresses during normal and abnormal erection
    Eran Linder-Ganz
    Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv 69978, Israel
    Ann N Y Acad Sci 1101:464-76. 2007
    ..The model's ability to determine internal stresses in the erect penis offers a new point of view on the mechanical factors involved with erection, and enables us to relate these data with different penile pathologies...
  22. ncbi Sildenafil inhibits the up-regulation of phosphodiesterase type 5 elicited with nicotine and tumour necrosis factor-alpha in cavernosal vascular smooth muscle cells: mediation by superoxide
    Matthew R Hotston
    Department of Urology, Bristol Royal Infirmary, Bristol, Avon, UK
    BJU Int 99:612-8. 2007
    ....
  23. ncbi Presence of LDL modified by myeloperoxidase in the penis in patients with vascular erectile dysfunction: a preliminary study
    Karim Zouaoui Boudjeltia
    Experimental Medicine Laboratory, ULB 222 Unit, ISPPC, CHU de Charleroi, Hôpital A Vésale, Montigny le Tilleul, Belgium
    Eur Urol 51:262-8; discussion 268-9. 2007
    ..We have developed a new monoclonal antibody against LDL modified by MPO (Mox-LDL) and have used it on penile biopsies from patients operated on for penile implant...
  24. ncbi Doppler evaluation of erectile dysfunction - part 2
    D Golijanin
    Department of Urology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Int J Impot Res 19:43-8. 2007
    ..This second part of the review article describes the various causes of ED and the interpretation and evaluation of color flow Doppler examination in ED...
  25. ncbi Management of honeymoon impotence
    Rany Shamloul
    Department of Andrology, Sexology and STDs, Cairo University, Cairo, Egypt
    J Sex Med 3:361-6. 2006
    ..While its exact causes are not yet elucidated, many studies recognize this problem as related to performance anxiety...
  26. ncbi Effect of chronic lithium administration on endothelium-dependent relaxation of rat corpus cavernosum: the role of nitric oxide and cyclooxygenase pathways
    Hamed Sadeghipour
    Department of Pharmacology, School of Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
    BJU Int 99:177-82. 2007
    ....
  27. ncbi Penile Doppler ultrasound assessment of the cavernous arteries
    Giuseppe Dachille
    Clinica Urologica, Ospedale San Giacomo, Monopoli, Bari, Italy
    Arch Ital Urol Androl 77:189-90. 2005
    ....
  28. ncbi Dramatic improvement of penile venous leakage upon testosterone administration. A case report and review of literature
    A A Yassin
    Clinic of Urology Andrology, Segeberger Kliniken, Norderstedt Hamburg, Germany
    Andrologia 38:34-7. 2006
    ..He was also testosterone deficient (1.8 ng ml(-1)). Upon testosterone administration his erectile function improved dramatically. Repeated cavernosography no longer showed venous leakage...
  29. ncbi Peak systolic velocities may be falsely low in young patients with erectile dysfunction
    Rany Shamloul
    Department of Andrology, Sexology and STDs, Cairo University, Cairo, Egypt
    J Sex Med 3:138-43. 2006
    ..However, several studies have demonstrated that in some cases Color Doppler Ultrasound (CDU) testing may result in wrong diagnosis because of anxiety and increased sympathetic stimulation...
  30. ncbi Polymorphism of endothelial nitric oxide synthase gene in patients with erectile dysfunction
    Erkan Erkan
    Department of Urology, Haseki Teaching and Research Hospital, Istanbul, Turkey
    J Sex Med 3:69-75; discussion 75-6. 2006
    ..The eNOS gene is located on the seventh somatic chromosome and the polymorphism of this gene has been reported to cause changes in the structure of enzyme system, resulting in disturbance of its activity...
  31. ncbi The pleiotropic effects of inducible nitric oxide synthase (iNOS) on the physiology and pathology of penile erection
    N F Gonzalez-Cadavid
    LABioMed at Harbor UCLA Medical Center, Torrance, CA, and Department of Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Curr Pharm Des 11:4041-6. 2005
    ....
  32. ncbi Does the clinical efficacy of vardenafil correlate with its effect on the endothelial function of cavernosal arteries? A pilot study
    Evsey B Mazo
    Russian State Medical University, Urology Department, Moscow, Russian Federation
    BJU Int 98:1054-8. 2006
    ....
  33. ncbi Tunica albuginea overlapping: a novel technique for the treatment of erectile dysfunction
    A Shafik
    Department of Surgery and Experimental Research, Faculty of Medicine, Cairo University, 2 Talaat Harb Street, Cairo 11121, Egypt
    Andrologia 37:180-4. 2005
    ..Microscopic examination of TA biopsies showed atrophy of the collagen fibres. Tunical overlapping aims at correction of TA flabbiness, corporal tissue support and improving of veno-occlusive mechanism...
  34. ncbi Peak systolic velocity in patients with arterial erectile dysfunction and peripheral arterial disease
    E Vicari
    Section of Endocrinology, Andrology and Internal Medicine, Department of Biomedical Sciences, University of Catania, Catania, Italy
    Int J Impot Res 18:175-9. 2006
    ..Therefore, ED patients with a severe arterial insufficiency should undergo an extensive echo-duplex examination...
  35. ncbi The synergism of penile venous surgery and oral sildenafil in treating patients with erectile dysfunction
    Hsien Sheng Wen
    Microsurgical Potency Reconstruction and Research Center, Taiwan Adventist Hospital, Taipei Medical University, Taipei, Taiwan
    Int J Androl 28:297-303. 2005
    ..It appears that together, oral sildenafil and penile venous surgery may provide an encouraging solution to impotent patients with veno-occlusive dysfunction who are non-responders to sildenafil...
  36. ncbi Initial validation of a novel rat model of vasculogenic erectile dysfunction with generalized atherosclerosis
    K Park
    Urology, Seoul National University College of Medicine, Chongno Gu, Seoul, Republic of Korea
    Int J Impot Res 17:424-30. 2005
    ..Based on these results, our study demonstrates that combination treatment of cholesterol diet with L-NAME would be used as a rapid, effective protocol of developing atherosclerotic rat model of VED...
  37. ncbi Erectile dysfunction in smokers: a penile dynamic and vascular study
    Allen D Seftel
    J Urol 173:2076. 2005
  38. ncbi [Conservative treatment of erectile dysfunction]
    György Papp
    Országos Gyógyintézeti Központ, Andrológiai és Urológiai Osztály, Budapest
    Orv Hetil 144:1061-6. 2003
    ..According to authors' opinion, the qualitative development of vasoactive drugs (efficacy extension and side-effect reduction) that can be simply and conveniently applied in the future...
  39. ncbi [Dynamic infusion cavernosometry and cavernosography (DICC)]
    Koichi Nagao
    First Department of Urology, Toho University School of Medicine
    Nihon Rinsho 60:192-5. 2002
  40. ncbi Honeymoon impotence: psychogenic or organic in origin?
    M F Usta
    Department of Urology, Akdeniz University Faculty of Medicine, Antalya, Turkey
    Urology 57:758-62. 2001
    ..We investigated the underlying penile vascular abnormalities in patients presenting with honeymoon impotence and sought to differentiate between psychogenic and organic etiologies...
  41. ncbi Diagnostic steps in the evaluation of patients with erectile dysfunction
    Dimitrios Hatzichristou
    Department of Urology and Center for Sexual and Reproductive Health, Aristotle University of Thessaloniki, Thessaloniki, Greece
    J Urol 168:615-20. 2002
    ..We determined the impact of the different diagnostic steps on the management strategy for erectile dysfunction...
  42. doi Why a combined intracavernosal injection with trimix and oral sildenafil is reliable therapy in the ultrasonographic evaluation of erectile dysfunction
    Jong Kwan Park
    Department of Urology, Medical School, and Institute for Medical Sciences, Chonbuk National University, Chonbuk, Korea
    BJU Int 102:993-7. 2008
    ....
  43. ncbi Imaging for erectile dysfunction
    Ian Eardley
    St James s University Hospital, Leeds, UK
    Curr Opin Urol 12:143-7. 2002
    ..In addition, the new techniques of functional magnetic resonance imaging and positron emission tomography scanning are beginning to offer new insights into the central mechanisms which control erections...
  44. ncbi The physiological role of androgens in penile erection: regulation of corpus cavernosum structure and function
    Abdulmaged Traish
    Boston University School of Medicine, Department of Urology, Boston, MA 02118, USA
    J Sex Med 2:759-70. 2005
    ....
  45. ncbi Corporeal structural and vascular micro architecture with X-ray micro computerized tomography in normal and diabetic rabbits: histopathological correlation
    D N Simopoulos
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 165:1776-82. 2001
    ..These results suggest that 3-D x-ray micro CT with molecular analysis may be a powerful tool for examining the pathophysiology of diabetic erectile dysfunction...
  46. ncbi Sildenafil citrate for penile hemodynamic determination: an alternative to intracavernosal agents in Doppler ultrasound evaluation of erectile dysfunction
    M M Baçar
    Department of Urology, University of Kirikkale Faculty of Medicine, Ankara, Turkey
    Urology 57:623-6; discussion 626-7. 2001
    ..To suggest a new noninvasive method for penile Doppler ultrasound (PDU) evaluation of erectile dysfunction using oral sildenafil citrate as an erection induction agent...
  47. ncbi Color Doppler appearance of penile cavernosal-spongiosal communications in patients with normal and impaired erection
    Michele Bertolotto
    Dipartimento di Scienze Cliniche, Morfologiche e Tecnologiche, Università du Trieste, 34149 Trieste, Italy
    Eur Radiol 12:2287-93. 2002
    ..During phase 5 (systolic peak reduction) all CSC disappeared. Color Doppler US allows evaluation of CSC both in patients with normal and impaired erection...
  48. ncbi Penile duplex pharmaco-ultrasonography revisited: revalidation of the parameters of the cavernous arterial response
    T G W Speel
    Department of Urology, University Medical Center, Nijmegen, The Netherlands
    J Urol 169:216-20. 2003
    ..We revalidate parameters of the cavernous arterial response (peak systolic blood flow velocity) and acceleration time using penile duplex pharmaco-ultrasonography...
  49. ncbi Sildenafil in erectile dysfunction: a critical review
    Andrea Salonia
    Department of Urology, University Vita Salute San Raffaele, Milan, Italy
    Curr Med Res Opin 19:241-62. 2003
    ..The review ends with several considerations regarding the direct and/or indirect impact of sildenafil over quality of life and quality of partnership...
  50. ncbi Androgens improve cavernous vasodilation and response to sildenafil in patients with erectile dysfunction
    Antonio Aversa
    AFaR CRCCS, Ospedale Fatebenefratelli Isola Tiberina, Rome, Italy
    Clin Endocrinol (Oxf) 58:632-8. 2003
    ..This led us to further investigate the effect(s) of androgen administration on cavernous arteries in patients failing sildenafil treatment...
  51. ncbi The effect of vascular endothelial growth factor and adeno-associated virus mediated brain derived neurotrophic factor on neurogenic and vasculogenic erectile dysfunction induced by hyperlipidemia
    Shahram S Gholami
    Department of Urology, University of California, San Francisco, USA
    J Urol 169:1577-81. 2003
    ....
  52. ncbi Biomechanical analysis of penile erections: penile buckling behaviour under axial loading and radial compression
    Gerald W Timm
    Department of Urologic Surgery, University of Minnesota, Minneapolis, MN, USA
    BJU Int 102:76-84. 2008
    ....
  53. doi Human neural crest stem cells transplanted in rat penile corpus cavernosum to repair erectile dysfunction
    Yun Seob Song
    Department of Urology, Soonchunhyang University School of Medicine, Seoul, Korea
    BJU Int 102:220-4; discussion 224. 2008
    ..K10 (K10) immortalized NCSC line was transplanted into the penile cavernosum of adult rats, as one of the causes of erectile dysfunction is damaged penile cavernous smooth muscle cells and sinus endothelial cells...
  54. ncbi Penile revascularization surgery in erectile dysfunction
    D Hauri
    Urologische Universitätsklinik, Zurich, Switzerland
    Urol Int 70:132-40. 2003
    ..Our technique produces good results in patients with diagnosed erectile dysfunction of vascular origin with a spontaneous erection when the occasion arises...
  55. doi Feasibility of dynamic 3-D color Doppler ultrasound for imaging penile vascular change in renal transplant patients with erectile dysfunction responding to sildenafil
    Ratna Chatterjee
    Department of Obstetrics and Gynaecology, University College London, London, UK
    Ultrasound Med Biol 34:885-91. 2008
    ..Differentiation of penile vasculogenic impotence from other causes is important for treatment...
  56. ncbi Management of peripheral arterial disease of the lower extremities in elderly patients
    Wilbert S Aronow
    Divisions of Cardiology and Geriatrics, Department of Medicine, New York Medical College, Valhalla, USA
    J Gerontol A Biol Sci Med Sci 59:172-7. 2004
    ..ischemia as manifested by rest pain, nonhealing ulcers, and/or infection or gangrene; and 3) vasculogenic impotence. However, amputation should be performed if tissue loss has progressed beyond the point of salvage, if ..
  57. doi Purification of a dimethyladenosine compound from silkworm pupae as a vasorelaxation substance
    Mi Young Ahn
    Department of Agricultural Biology, National Institute of Agricultural Science and Technology, 61 Seodun Dong, Kwonsun Gu, Suwon 441 100, South Korea
    J Ethnopharmacol 117:115-22. 2008
    ..These results imply that dimethyladenosine may be a lead compound for the development and improvement of vasculogenic impotence drugs through phosphodiesterase inhibition and NO production in endothelial cells.
  58. ncbi Penile oxygen saturation in the flaccid and erect penis in men with and without erectile dysfunction
    Priya Padmanabhan
    New York University School of Medicine, Department of Urology, 150 East 32 Street, New York, NY 10012, USA
    J Androl 28:223-8. 2007
    ..Limited invasive blood gas measurements in human models have shown decreased oxygen tension in vasculogenic impotence. Normative data on flaccid and erect oxygen saturation (StO(2)) levels are lacking due to the invasive ..
  59. ncbi Cavernous arterial and arteriolar circulation in patients with erectile dysfunction: a power Doppler study
    L M Sarteschi
    Department of Andrology, University of Pisa School of Medicine, Italy
    J Urol 159:428-32. 1998
    ..Our preliminary data suggest that the intracavernous arteriolar component may have a significant role in the genesis of some forms of vasculogenic impotence.
  60. ncbi Management of peripheral arterial disease
    Wilbert S Aronow
    Divisions of Cardiology and Geriatrics, Department of Medicine, New York Medical College Westchester Medical Center, Valhalla, NY 10595, USA
    Cardiol Rev 13:61-8. 2005
    ..ischemia as manifested by rest pain, nonhealing ulcers, and/or infection or gangrene; and 3) vasculogenic impotence. However, amputation should be performed if tissue loss has progressed beyond the point of salvage, if ..
  61. ncbi Is obesity an underlying factor in erectile dysfunction?
    W S Chung
    Department of Urology, Medical Research Center, Ewha Woman s University College of Medicine, Seoul, Korea
    Eur Urol 36:68-70. 1999
    ..We conducted a study to evaluate the impact of obesity on erectile function in men with erectile dysfunction...
  62. ncbi Management of peripheral arterial disease of the lower extremities
    Wilbert S Aronow
    Department of Medicine, Division of Cardiology, New York Medical College, Valhalla, NY 10595, USA
    Compr Ther 33:247-56. 2007
    ..claudication in persons interfering with work or lifestyle, (2) limb salvage in persons with limb-threatening ischemia as manifested by rest pain, nonhealing ulcers, and/or infection or gangrene, and (3) vasculogenic impotence.
  63. pmc Peripheral arterial disease in the elderly
    Wilbert S Aronow
    Cardiology Division, Department of Medicine, New York Medical College, Valhalla, New York 10595, USA
    Clin Interv Aging 2:645-54. 2007
    ..claudication in patients interfering with work or lifestyle; (2) limb salvage in patients with limb-threatening ischemia as manifested by rest pain, nonhealing ulcers, and/or infection or gangrene; and (3) vasculogenic impotence.
  64. ncbi Magnetic resonance imaging as a potential tool for objective visualization of venous leakage in patients with veno-occlusive erectile dysfunction
    D G Kurbatov
    Clinical Hospital 6 of Federal Medico Biological Agency, Moscow, Russia
    Int J Impot Res 20:192-8. 2008
    ..MRI visualized venous leakage patients, in which DICC did not confirm venous leakage. MRI may be a useful diagnostic tool for assessing veno-occlusive dysfunction in ED patients and may improve diagnosis of venous leakage visualization...
  65. ncbi Erectile dysfunction as a sentinel marker of endothelial dysfunction disease
    B Lojanapiwat
    Division of Urology, Department of Surgery, Faculty of Medicine, Chiang Mai University, 110 Intravaroros Road, Chiang Mai 50200, Thailand
    Singapore Med J 50:698-701. 2009
    ..Brachial flow-mediated vasodilation (FMD) is one of the accurate tests for evaluating endothelial function. We compared the endothelial function by FMD between ED patients without clinical signs of vascular disease and non-ED patients...
  66. doi Hypogastric artery preservation during endovascular aortic aneurysm repair: is it important?
    Peter H Lin
    Division of Vascular Surgery and Endovascular Therapy, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA
    Semin Vasc Surg 22:193-200. 2009
    ..Lastly, treatment strategies to preserve the hypogastric artery thereby obviating the need for hypogastric artery embolization are discussed...
  67. doi Clinical experience of a refined penile venous stripping surgery procedure for patients with erectile dysfunction: is it a viable option?
    Geng Long Hsu
    Microsurgical Potency Reconstruction and Research Center, Department of Urology, China Medical University and Hospital, Taichung and Taipei, Taiwan
    J Androl 31:271-80. 2010
    ..8 vs 7.9 +/- 3.2, P < .001, n = 121) during the same period of follow-up was, however, noted in the control group. This refined penile venous stripping surgery delivered favorable results and is a viable alternative for treating VOD...
  68. ncbi The prevalence and predictors of erectile dysfunction in men with newly diagnosed with type 2 diabetes mellitus
    Adel Al-Hunayan
    Department of Surgery Division of Urology, Kuwait University, Kuwait
    BJU Int 99:130-4. 2007
    ..To determine the prevalence of and risk factors for erectile dysfunction (ED) in men newly diagnosed with type 2 diabetes mellitus (DM)...
  69. ncbi A mathematical model of penile vascular dysfunction and its application to a new diagnostic technique
    Ofer Barnea
    Department of Biomedical Engineering, Tel Aviv University, Ramat Aviv 69788, Israel
    Ann N Y Acad Sci 1101:439-52. 2007
    ..In preliminary measurements on young healthy volunteers, the feasibility of the measurement has been demonstrated. More studies are required to confirm the diagnostic value of the measurements...
  70. ncbi Heart rate reduction with ivabradine improves erectile dysfunction in parallel to decrease in atherosclerotic plaque load in ApoE-knockout mice
    Magnus Baumhakel
    Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, D 66421 Homburg Saar, Germany
    Atherosclerosis 212:55-62. 2010
    ..To determine the effect of heart rate reduction with ivabradine on atherosclerotic lesions and erectile dysfunction...
  71. doi Reversal of voltage-dependent erectile responses in the Zucker obese-diabetic rat by rosuvastatin-altered RhoA/Rho-kinase signaling
    Christopher J Wingard
    Brody School of Medicine at East Carolina University, Department of Physiology, Greenville, NC 27834, USA
    J Sex Med 6:269-78. 2009
    ..Clinical studies suggest that a pleiotropic effect of statin's ability to enhance vascular relaxation might be through an impact on nitric oxide signaling or through a regulation of RhoA activation...
  72. doi An analysis of sexual health information on radical prostatectomy websites
    John P Mulhall
    Department of Urology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    BJU Int 105:68-72. 2010
    ..To define the nature of information posted on websites related to radical prostatectomy (RP), specifically its accuracy and comprehensiveness, as RP is associated with erectile dysfunction (ED)...
  73. ncbi Use and abuse of Rigiscan in the diagnosis of erectile dysfunction
    Emmanuele A Jannini
    Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L Aquila, L Aquila, Italy
    J Sex Med 6:1820-9. 2009
    ..Shall we continue to consider these tools as a diagnostic gold standard in ED diagnosis?..
  74. doi Erectile function after posterior urethroplasty for pelvic fracture-urethral distraction defect injuries
    Jennifer T Anger
    Department of Urology, University of California, Los Angeles, CA 90404, USA
    BJU Int 104:1126-9. 2009
    ....
  75. doi Office management of peripheral arterial disease
    Wilbert S Aronow
    Department of Medicine, New York Medical College, Valhalla, NY, USA
    Am J Med 123:790-2. 2010
    ..are incapacitating claudication interfering with work or lifestyle in patients; limb salvage in patients with limb-threatening ischemia as manifested by rest pain, nonhealing ulcers, infection, or gangrene; and vasculogenic impotence.
  76. ncbi Vascular risk factors as predictors of sexual function following coronary artery bypass graft
    Osama A Mohamed
    Scott Department of Urology, Baylor College of Medicine, 7490 Bromton Road, Houston, TX 77025, USA
    J Sex Med 6:2017-23. 2009
    ..A strong association between cardiovascular risk factors and erectile dysfunction (ED) was suggested. Coronary artery bypass grafting (CABG) is the gold standard for surgical myocardial revascularization...
  77. ncbi [Vascular factors in the pathogenesis of diabetic erectile dysfunction]
    Rong Yang
    Department of Urology, Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical College, Nanjing, Jiangsu 210008, China
    Zhonghua Nan Ke Xue 13:255-9. 2007
    ..In the development of diabetic vasculopathy, some vasomotion factors and growth factors undergo conspicuous changes, which may be significantly correlated with the development of diabetic erectile dysfunction...
  78. ncbi Cavernous nerve graft reconstruction using an autologous nerve guide to restore potency
    Masaki Fujioka
    Department of Plastic and Reconstructive Surgery, National Nagasaki Medical Center, Nagasaki, Japan
    BJU Int 100:1107-9. 2007
    ..To present our experience of cavernous nerve graft reconstruction, using an autologous nerve vein-guide technique, to restore potency...
  79. ncbi Derangements in endothelial cell-to-cell junctions involved in the pathogenesis of hypercholesterolemia-induced erectile dysfunction
    Ji Kan Ryu
    Department of Urology and National Research Laboratory of Regenerative Sexual Medicine, Inha University School of Medicine, 7 206 3rd Street, Shinheung Dong, Jung Gu, Incheon, Korea
    J Sex Med 6:1893-907. 2009
    ..Endothelial cell-to-cell junctions are crucial for vascular formation, networking, and remodeling of blood vessels as well as for inducing and integrating intracellular signals...
  80. doi Correlation between Lower Urinary Tract Symptoms (LUTS) and sexual function in benign prostatic hyperplasia: impact of treatment of LUTS on sexual function
    Jae Hun Jung
    Department of Urology, School of Medicine, Gyeongsang National University, Gyeongsang Institute of Health Sciences, Jinju, South Korea
    J Sex Med 6:2299-304. 2009
    ..Although many reports have shown a relationship between lower urinary tract symptoms (LUTS) and sexual function (SF), it is not known which symptom(s) among LUTS should be treated to improve SF...
  81. ncbi Penile revascularization for erectile dysfunction: a systematic review and meta-analysis of effectiveness and complications
    Ali Reza Babaei
    Department of Plastic Surgery, AJA University of Medical Sciences, Tehran, Iran
    Urol J 6:1-7. 2009
    ..We aimed to determine the subjective and objective outcomes of PR surgery in patients with arteriogenic ED...
  82. doi Stereological and biochemical analysis of muscular and connective tissue components in the penile corpus cavernosum adjacent to the fibrous plaque of Peyronie's disease
    Waldemar S Costa
    Urogenital Research Unit, State Universiy of Rio de Janeiro, Rio de Janeiro, Brazil
    BJU Int 103:212-6. 2009
    ..Because this fibrotic reaction is mediated by various inflammatory soluble factors, adjacent connective tissues might also be affected and this secondary effect might explain, for example, the erectile dysfunction that occurs in PD...
  83. ncbi Penile colour duplex ultrasonography as a screening tool for venogenic erectile dysfunction
    H S Teh
    Department of Radiology, Changi General Hospital, 2, Simei Street 3, Singapore 529889
    Ann Acad Med Singapore 31:165-9. 2002
    b>Vasculogenic impotence is one of the major causes of erectile dysfunction. Cavernosometry and cavernosography is traditionally the gold standard for evaluation of venogenic impotence...
  84. doi The associations among eNOS G894T gene polymorphism, erectile dysfunction, and benign prostate hyperplasia-related lower urinary tract symptoms
    Yung Chin Lee
    Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    J Sex Med 6:3158-65. 2009
    ..However, there has been no report investigating the eNOS G894T genetic susceptibility factor for both ED and BPH/LUTS...
  85. ncbi Should erectile dysfunction be treated as secondary prevention for coronary disease?
    Graham Jackson
    Int J Clin Pract 60:1335. 2006
  86. ncbi Chronic administration of an oral Rho kinase inhibitor prevents the development of vasculogenic erectile dysfunction in a rat model
    Kwanjin Park
    Department of Urology, Korea Cancer Center Hospital, Seoul, Korea
    J Sex Med 3:996-1003. 2006
    ..It has been shown that the Rho/Rho kinase calcium sensitizing pathway has been implicated in the pathogenesis of erectile dysfunction as well as systemic atherosclerosis...
  87. ncbi Erectile dysfunction: a marker of silent coronary artery disease
    Graham Jackson
    Eur Heart J 27:2613-4. 2006
  88. ncbi [Erectile dysfunction arising from polyarteritis nodosa: a case report]
    Takanori Kitauchi
    Department of Urology, Nara Medical University
    Hinyokika Kiyo 48:663-6. 2002
    ..Internal-pudendal angiography revealed multiple microaneurysms in the bilateral internal pudendal arteries, suggesting that nodal polyarteritis caused arterial erectile dysfunction...
  89. ncbi A male cardiovascular sexual health clinic
    Graham Jackson
    Int J Clin Pract 56:631. 2002
  90. ncbi [Erectile dysfunction]
    Peter Lyngdorf
    Klinik for seksuelle dysfunktioner, Gentoftegade 49, DK 2830 Gentofte
    Ugeskr Laeger 164:4779-83. 2002
  91. pmc Tonic-clonic seizures in patients taking sildenafil
    Ronit Gilad
    Department of Neurology, Wolfson Medical Center, Holon 58100, Israel
    BMJ 325:869. 2002
  92. ncbi Doppler US evaluation of erectile dysfunction
    S H Kim
    Department of Radiology, Seoul National University Hospital, 28 Yongon Dong, Chongno Gu, Seoul 110 744, Korea
    Abdom Imaging 27:578-87. 2002
  93. ncbi [Erectile dysfunction in men under 39]
    Haruaki Sasaki
    Showa University, Northern Yokohama Hospital
    Nihon Rinsho 60:469-72. 2002
  94. ncbi [Penile venous surgery]
    Haruaki Sasaki
    Showa University, Northern Yokohama Hospital
    Nihon Rinsho 60:306-9. 2002
  95. ncbi [Color Doppler ultrasonography]
    Haruaki Sasaki
    Showa University, Northern Yokohama Hospital
    Nihon Rinsho 60:178-82. 2002
  96. ncbi Accumulated endogenous NOS inhibitors, decreased NOS activity, and impaired cavernosal relaxation with ischemia
    Hitoshi Masuda
    Department of Urology and Reproductive Medicine, Institute of Biomaterials and Bioengineering, Graduate School, Tokyo Medical and Dental University, Tokyo 101 0062, Japan
    Am J Physiol Regul Integr Comp Physiol 282:R1730-8. 2002
    ..These results suggest that the impaired NO-mediated cavernosal relaxations after ischemia are closely related to the decreased NOS activity and the increased accumulation of L-NMMA and ADMA...
  97. ncbi Usefulness of power Doppler ultrasonography in evaluating erectile dysfunction
    A J Golubinski
    Department of Urology, Pomeranian Academy of Medicine, ul Powstancow Wlkp 72, 70 111 Szczecin, Poland
    BJU Int 89:779-82. 2002
    ..To evaluate deep penile arterial flow after an intracavernosal injection with papaverine in patients with erectile dysfunction (ED)...
  98. ncbi Combined Doppler, blood gas, and Bennet quick test for venous leak practical for prepenile prosthesis testing in solo private offices
    A H Horan
    Department of Surgery, VAMC Fresno, Fresno, California 93704, USA
    Tech Urol 7:288-9. 2001
    ..The results in 90 patients suggest its selective use in the subset of nonresponding, nonleakers who have open cavernous arteries by Doppler, typically diabetics...
  99. ncbi The efficacy of sildenafil in different etiologies of erectile dysfunction
    M Basar
    Department of Urology, Kirikkale University, Faculty of Medicine Ankara Numune Hospital, Turkey
    Int Urol Nephrol 32:403-7. 2001
    ..The aim of this study was to evaluate the efficacy of sildenafil and success of treatment in particular etiological causes in erectile dysfunction lasting more than 3 months...
  100. ncbi Feasibility of multi-slice computed tomography in the diagnosis of arteriogenic erectile dysfunction
    Y Kawanishi
    Department of Urology, Takamatsu Red Cross Hospital, Kagawa, Japan
    BJU Int 88:390-5. 2001
    ....
  101. ncbi Gene expression profiling of an arteriogenic impotence model
    C S Lin
    Knuppe Molecular Urology Laboratory, School of Medicine, University of California at San Francisco, San Francisco, CA 94143 1695, USA
    Biochem Biophys Res Commun 285:565-9. 2001
    ..Finally, VEGF, whose induction has been identified in many other ischemic tissues, was not induced in corpus cavernous tissue of ligated rats...

Research Grants46

  1. MOLECULAR MECHANISMS OF CORPUS CAVERNOSUM FIBROSIS
    Robert Moreland; Fiscal Year: 1999
    ..b>Vasculogenic impotence secondary to veno-occlusive dysfunction from structural changes is a common cause of erectile impairment ..
  2. TREATMENT AND PREVENTION OF IMPOTENCE
    Tom Lue; Fiscal Year: 1990
    ..In addition, we hope to perfect the treatment of vasculogenic impotence with new procedures that will correct arterial insufficiency and venous incompetence...
  3. FEMALE SEXUAL AROUSAL: CLITORAL AND VAGINAL PHYSIOLOGY
    Abdulmaged Traish; Fiscal Year: 2003
    ....
  4. FEMALE SEXUAL AROUSAL: CLITORAL AND VAGINAL PHYSIOLOGY
    Abdulmaged Traish; Fiscal Year: 2002
    ....
  5. FEMALE SEXUAL AROUSAL: CLITORAL AND VAGINAL PHYSIOLOGY
    Abdulmaged Traish; Fiscal Year: 2001
    ....
  6. FEMALE SEXUAL AROUSAL: CLITORAL AND VAGINAL PHYSIOLOGY
    Abdulmaged Traish; Fiscal Year: 2000
    ....
  7. Racial/Ethnic Disparities in Fall Risk and Bone Strength Among Men
    ANDRE ARAUJO; Fiscal Year: 2009
    ..Findings will continue to inform our understanding of bone fragility, bone loss, and osteoporosis. ..
  8. Volume-Outcomes in Incontinence Surgery
    Jennifer Anger; Fiscal Year: 2005
    ..The primary outcome will be re-operation rates, repeat sling procedures (for failures), and other postoperative complications, stratified by high and low volume surgeons and hospitals. ..
  9. ERECTILE DYSFUNCTION AND NITRIC OXIDE SYNTHASE IN AGING
    Nestor Gonzalez Cadavid; Fiscal Year: 2006
    ....
  10. Mesenchymal Stem Cells for Myocardial Infarction
    Robert Kloner; Fiscal Year: 2006
    ..abstract_text> ..
  11. ERECTILE DYSFUNCTION AND NITRIC OXIDE SYNTHASE IN AGING
    Nestor Gonzalez Cadavid; Fiscal Year: 2006
    ....
  12. CELL-SELECTIVE EXPRESSION OF FIBROTIC GENE PATHWAYS
    Nestor Gonzalez Cadavid; Fiscal Year: 2007
    ..We expect that our studies would lead to the detection of novel targets of antifibrotic therapy for penile and vascular diseases of considerable public health impact. [unreadable] [unreadable] [unreadable]..
  13. Cardio-vascular Impact of Inhaled Multi-wall Carbon Nanotubes
    Christopher J Wingard; Fiscal Year: 2010
    ..Test the hypothesis that inhalation of MWCNT alters vascular reactivity via impared adenosine signaling. Specific Aim 4. Assess the role of endothiela nitric oxide, oxidative stress and vascular function in MWCNT cardiotoxicity. ..
  14. Race, Comorbidity & Long Term Prostate Cancer Outcomes
    David Penson; Fiscal Year: 2007
    ..Specifically, it will help newly-diagnosed patients make more informed decisions regarding treatment and will help researchers design novel interventions to improve the quality of life of prostate cancer survivors. ..
  15. QUALITY-OF-CARE INDICATORS FOR OVERACTIVE BLADDER SYMPTOMS
    Jennifer Anger; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  16. 2007 AUA/SBUR Summer Research Conference "Clinical Trials and Outcomes Research"
    David Penson; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  17. Roles for Phospholipase A2 Signaling in Prostate Development
    Edward Schaeffer; Fiscal Year: 2008
    ....
  18. Racial/Ethnic Disparities in Fall Risk and Bone Strength Among Men
    Andre B Araujo; Fiscal Year: 2010
    ..Findings will continue to inform our understanding of bone fragility, bone loss, and osteoporosis. ..
  19. Race, Comorbidity & Long Term Prostate Cancer Outcomes
    David Penson; Fiscal Year: 2008
    ..Specifically, it will help newly-diagnosed patients make more informed decisions regarding treatment and will help researchers design novel interventions to improve the quality of life of prostate cancer survivors. ..
  20. Cardio-vascular Impact of Inhaled Multi-wall Carbon Nanotubes
    Christopher Wingard; Fiscal Year: 2009
    ..Test the hypothesis that inhalation of MWCNT alters vascular reactivity via impared adenosine signaling. Specific Aim 4. Assess the role of endothiela nitric oxide, oxidative stress and vascular function in MWCNT cardiotoxicity. ..
  21. CELL-SELECTIVE EXPRESSION OF FIBROTIC GENE PATHWAYS
    Nestor Gonzalez Cadavid; Fiscal Year: 2008
    ..We expect that our studies would lead to the detection of novel targets of antifibrotic therapy for penile and vascular diseases of considerable public health impact. [unreadable] [unreadable] [unreadable]..
  22. Cardio-vascular Impact of Inhaled Multi-wall Carbon Nanotubes
    Christopher Wingard; Fiscal Year: 2008
    ..Test the hypothesis that inhalation of MWCNT alters vascular reactivity via impared adenosine signaling. Specific Aim 4. Assess the role of endothiela nitric oxide, oxidative stress and vascular function in MWCNT cardiotoxicity. ..
  23. QUALITY-OF-CARE INDICATORS FOR OVERACTIVE BLADDER SYMPTOMS
    Jennifer Anger; Fiscal Year: 2008
    ..abstract_text> ..
  24. Mesenchymal Stem Cells for Myocardial Infarction
    Robert Kloner; Fiscal Year: 2005
    ..abstract_text> ..
  25. ERECTILE DYSFUNCTION AND NITRIC OXIDE SYNTHASE IN AGING
    Nestor Gonzalez Cadavid; Fiscal Year: 2004
    ....
  26. ERECTILE DYSFUNCTION AND NITRIC OXIDE SYNTHASE IN AGING
    Nestor Gonzalez Cadavid; Fiscal Year: 1999
    ..The long-term goal is to validate pre-clinically the use of these agents for medical treatment of erectile dysfunction associated with aging. ..
  27. COLLABORATIVE R01-CARDIAC GRAFTS-FUNCTIONAL ANALYSES
    Robert Kloner; Fiscal Year: 2000
    ....
  28. ERECTILE DYSFUNCTION AND NITRIC OXIDE SYNTHASE IN AGING
    Nestor Gonzalez Cadavid; Fiscal Year: 2000
    ..The long-term goal is to validate pre-clinically the use of these agents for medical treatment of erectile dysfunction associated with aging. ..
  29. Erectile Function and the Influence of Rho-kinase
    Christopher Wingard; Fiscal Year: 2001
    ..If our hypothesis is correct, future studies may examine other modulators of this novel regulatory pathway and how potential alterations of this pathway may aid in treatment of erectile dysfunction. ..
  30. COLLABORATIVE R01-CARDIAC GRAFTS-FUNCTIONAL ANALYSES
    Robert Kloner; Fiscal Year: 2001
    ....
  31. ERECTILE DYSFUNCTION AND NITRIC OXIDE SYNTHASE IN AGING
    Nestor Gonzalez Cadavid; Fiscal Year: 2001
    ..The long-term goal is to validate pre-clinically the use of these agents for medical treatment of erectile dysfunction associated with aging. ..
  32. COLLABORATIVE R01-CARDIAC GRAFTS-FUNCTIONAL ANALYSES
    Robert Kloner; Fiscal Year: 2002
    ....
  33. Erectile Function and the Influence of Rho-kinase
    Christopher Wingard; Fiscal Year: 2002
    ..If our hypothesis is correct, future studies may examine other modulators of this novel regulatory pathway and how potential alterations of this pathway may aid in treatment of erectile dysfunction. ..
  34. Erectile Function and the Influence of Rho-kinase
    Christopher Wingard; Fiscal Year: 2003
    ..If our hypothesis is correct, future studies may examine other modulators of this novel regulatory pathway and how potential alterations of this pathway may aid in treatment of erectile dysfunction. ..
  35. ERECTILE DYSFUNCTION AND NITRIC OXIDE SYNTHASE IN AGING
    Nestor Gonzalez Cadavid; Fiscal Year: 2003
    ....
  36. COLLABORATIVE R01-CARDIAC GRAFTS-FUNCTIONAL ANALYSES
    Robert Kloner; Fiscal Year: 2003
    ....
  37. Mesenchymal Stem Cells for Myocardial Infarction
    Robert Kloner; Fiscal Year: 2003
    ..abstract_text> ..
  38. ERECTILE DYSFUNCTION AND NITRIC OXIDE SYNTHASE IN AGING
    Nestor Gonzalez Cadavid; Fiscal Year: 2004
    ....
  39. Mesenchymal Stem Cells for Myocardial Infarction
    Robert Kloner; Fiscal Year: 2004
    ..abstract_text> ..
  40. Biologic Ventricular Assist Device
    Robert Kloner; Fiscal Year: 2004
    ..Identification and characterization of transplants will be carried out with PCR analysis of the Y chromosome (male cells into female host), detailed histologic analysis and immunostaining for muscle cell markers. ..
  41. ERECTILE DYSFUNCTION AND NITRIC OXIDE SYNTHASE IN AGING
    Nestor Gonzalez Cadavid; Fiscal Year: 2005
    ....
  42. COLLABORATIVE R01-CARDIAC GRAFTS-FUNCTIONAL ANALYSES
    Robert Kloner; Fiscal Year: 1999
    ....