vasculogenic impotence

..Further studies are likely to refine patient selection but are unlikely to expand the therapeutic use of these procedures...

..However, there are limited research and data supporting this association in humans...

..Endothelial dysfunction may be correlated with a loss of adenosine A(2B) receptor activity in penile vessels from men with vasculogenic ED...

..Hypothyroidism has been reported to occur in 6% of impotent men. There is some evidence suggesting that hypothyroidism may be a cause of impotence...

..We found that the cure rate of this procedure is maintained and long-term follow-up shows good results, especially in the young nonsmokers...

..Our data indicate that one should always consider the possibility of PD in older patients with diabetes, presenting with only ED...

..Penile venous ligation, especially on the site-specific veins, is still the choice of treatment for the trauma-induced penile veno-occlusive erectile dysfunction, and the result is satisfactory...

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..It is essential to ensure cavernosal relaxation using phentolamine before a Doppler US diagnosis of venous leak is made. This two-stage assessment will allow this to be done efficiently and with a low risk of priapism...

..5+/-2.8 ng/mL), and those without dyslipidemia (4.8+/-2.8 ng/mL) (P<0.05). CONCLUSION: Vascular risk factors are associated with an elevated plasma TGF-beta1 level, which may contribute to cavernous fibrosis and ED...

..CONCLUSIONS: CA anatomy is variable, and the PSV differs between sites, irrespective of the presence of a vascular component to erectile dysfunction. Thus, anatomic variations should be considered when interpreting Doppler sonography...

..Also, decreases in contraction responses may depend on diminished adrenoceptor density...

..Recent results have demonstrated a positive impact of EECP on patients with ischemic heart disease (IHD)-associated erectile dysfunction (ED)...

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..In addition, only few studies have investigated the changes in structure and function of penile arteries in cardiovascular risk situations leading to ED...

..In addition, the assessment of heart rate variability at rest, during metronomic breathing, Valsalva maneuver, and active standing might be helpful to identify an autonomic neuropathy as the cause of erectile dysfunction...

..There are convincing long-term results with a high degree of patient and partner satisfaction, high patient acceptance and a good functional durability of the mostly three-part hydraulic implants...

..Invasive testing for ED has decreased due to the high responder rate for oral PDE-5 inhibitors...

..Phosphodiesterase type 5 (PDE5) inhibitors and angiotensin II receptor blockers (ARB) are both common and efficient therapy in patients with ED and arterial hypertension, respectively...

..We therefore believe that the clinical recurrence may not be due to venous regeneration, and penile venous surgery, if properly performed, may be durable, although larger studies will be required...

..The model's ability to determine internal stresses in the erect penis offers a new point of view on the mechanical factors involved with erection, and enables us to relate these data with different penile pathologies...

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..We have developed a new monoclonal antibody against LDL modified by MPO (Mox-LDL) and have used it on penile biopsies from patients operated on for penile implant...

..This second part of the review article describes the various causes of ED and the interpretation and evaluation of color flow Doppler examination in ED...

..While its exact causes are not yet elucidated, many studies recognize this problem as related to performance anxiety...

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..He was also testosterone deficient (1.8 ng ml(-1)). Upon testosterone administration his erectile function improved dramatically. Repeated cavernosography no longer showed venous leakage...

..However, several studies have demonstrated that in some cases Color Doppler Ultrasound (CDU) testing may result in wrong diagnosis because of anxiety and increased sympathetic stimulation...

..The eNOS gene is located on the seventh somatic chromosome and the polymorphism of this gene has been reported to cause changes in the structure of enzyme system, resulting in disturbance of its activity...

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..Microscopic examination of TA biopsies showed atrophy of the collagen fibres. Tunical overlapping aims at correction of TA flabbiness, corporal tissue support and improving of veno-occlusive mechanism...

..Therefore, ED patients with a severe arterial insufficiency should undergo an extensive echo-duplex examination...

..It appears that together, oral sildenafil and penile venous surgery may provide an encouraging solution to impotent patients with veno-occlusive dysfunction who are non-responders to sildenafil...

..Based on these results, our study demonstrates that combination treatment of cholesterol diet with L-NAME would be used as a rapid, effective protocol of developing atherosclerotic rat model of VED...

..According to authors' opinion, the qualitative development of vasoactive drugs (efficacy extension and side-effect reduction) that can be simply and conveniently applied in the future...

..We investigated the underlying penile vascular abnormalities in patients presenting with honeymoon impotence and sought to differentiate between psychogenic and organic etiologies...

..Specific diagnostic procedures may be limited in patients with primary erectile dysfunction or those without risk factors. Such clinical data support previously published guidelines for erectile dysfunction management...

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..In addition, the new techniques of functional magnetic resonance imaging and positron emission tomography scanning are beginning to offer new insights into the central mechanisms which control erections...

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..These results suggest that 3-D x-ray micro CT with molecular analysis may be a powerful tool for examining the pathophysiology of diabetic erectile dysfunction...

..To suggest a new noninvasive method for penile Doppler ultrasound (PDU) evaluation of erectile dysfunction using oral sildenafil citrate as an erection induction agent...

..During phase 5 (systolic peak reduction) all CSC disappeared. Color Doppler US allows evaluation of CSC both in patients with normal and impaired erection...

..Sensitivity was 66% and specificity was 71%. CONCLUSIONS: The results of this study show that acceleration time has more power than peak systolic velocity to diagnose atherosclerotic erectile dysfunction...

..The review ends with several considerations regarding the direct and/or indirect impact of sildenafil over quality of life and quality of partnership...

..This led us to further investigate the effect(s) of androgen administration on cavernous arteries in patients failing sildenafil treatment...

..VEGF and AAV-BDNF appeared to alleviate partially these changes. CONCLUSIONS: A high fat diet caused erectile dysfunction with accompanying neurological and vascular changes. VEGF and AAV-BDNF seemed to alleviate these problems...

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..K10 (K10) immortalized NCSC line was transplanted into the penile cavernosum of adult rats, as one of the causes of erectile dysfunction is damaged penile cavernous smooth muscle cells and sinus endothelial cells...

..Our technique produces good results in patients with diagnosed erectile dysfunction of vascular origin with a spontaneous erection when the occasion arises...

..Differentiation of penile vasculogenic impotence from other causes is important for treatment...

..ischemia as manifested by rest pain, nonhealing ulcers, and/or infection or gangrene; and 3) vasculogenic impotence. However, amputation should be performed if tissue loss has progressed beyond the point of salvage, if ..

..These results imply that dimethyladenosine may be a lead compound for the development and improvement of vasculogenic impotence drugs through phosphodiesterase inhibition and NO production in endothelial cells.

..Limited invasive blood gas measurements in human models have shown decreased oxygen tension in vasculogenic impotence. Normative data on flaccid and erect oxygen saturation (StO(2)) levels are lacking due to the invasive ..

..Our preliminary data suggest that the intracavernous arteriolar component may have a significant role in the genesis of some forms of vasculogenic impotence.

..ischemia as manifested by rest pain, nonhealing ulcers, and/or infection or gangrene; and 3) vasculogenic impotence. However, amputation should be performed if tissue loss has progressed beyond the point of salvage, if ..

..We conducted a study to evaluate the impact of obesity on erectile function in men with erectile dysfunction...

..claudication in persons interfering with work or lifestyle, (2) limb salvage in persons with limb-threatening ischemia as manifested by rest pain, nonhealing ulcers, and/or infection or gangrene, and (3) vasculogenic impotence.

..claudication in patients interfering with work or lifestyle; (2) limb salvage in patients with limb-threatening ischemia as manifested by rest pain, nonhealing ulcers, and/or infection or gangrene; and (3) vasculogenic impotence.

..MRI visualized venous leakage patients, in which DICC did not confirm venous leakage. MRI may be a useful diagnostic tool for assessing veno-occlusive dysfunction in ED patients and may improve diagnosis of venous leakage visualization...

..Brachial flow-mediated vasodilation (FMD) is one of the accurate tests for evaluating endothelial function. We compared the endothelial function by FMD between ED patients without clinical signs of vascular disease and non-ED patients...

..Lastly, treatment strategies to preserve the hypogastric artery thereby obviating the need for hypogastric artery embolization are discussed...

..8 vs 7.9 +/- 3.2, P < .001, n = 121) during the same period of follow-up was, however, noted in the control group. This refined penile venous stripping surgery delivered favorable results and is a viable alternative for treating VOD...

..To determine the prevalence of and risk factors for erectile dysfunction (ED) in men newly diagnosed with type 2 diabetes mellitus (DM)...

..In preliminary measurements on young healthy volunteers, the feasibility of the measurement has been demonstrated. More studies are required to confirm the diagnostic value of the measurements...

..To determine the effect of heart rate reduction with ivabradine on atherosclerotic lesions and erectile dysfunction...

..Clinical studies suggest that a pleiotropic effect of statin's ability to enhance vascular relaxation might be through an impact on nitric oxide signaling or through a regulation of RhoA activation...

..To define the nature of information posted on websites related to radical prostatectomy (RP), specifically its accuracy and comprehensiveness, as RP is associated with erectile dysfunction (ED)...

..Shall we continue to consider these tools as a diagnostic gold standard in ED diagnosis?..

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..are incapacitating claudication interfering with work or lifestyle in patients; limb salvage in patients with limb-threatening ischemia as manifested by rest pain, nonhealing ulcers, infection, or gangrene; and vasculogenic impotence.

..A strong association between cardiovascular risk factors and erectile dysfunction (ED) was suggested. Coronary artery bypass grafting (CABG) is the gold standard for surgical myocardial revascularization...

..In the development of diabetic vasculopathy, some vasomotion factors and growth factors undergo conspicuous changes, which may be significantly correlated with the development of diabetic erectile dysfunction...

..To present our experience of cavernous nerve graft reconstruction, using an autologous nerve vein-guide technique, to restore potency...

..Endothelial cell-to-cell junctions are crucial for vascular formation, networking, and remodeling of blood vessels as well as for inducing and integrating intracellular signals...

..Although many reports have shown a relationship between lower urinary tract symptoms (LUTS) and sexual function (SF), it is not known which symptom(s) among LUTS should be treated to improve SF...

..We aimed to determine the subjective and objective outcomes of PR surgery in patients with arteriogenic ED...

..Because this fibrotic reaction is mediated by various inflammatory soluble factors, adjacent connective tissues might also be affected and this secondary effect might explain, for example, the erectile dysfunction that occurs in PD...

b>Vasculogenic impotence is one of the major causes of erectile dysfunction. Cavernosometry and cavernosography is traditionally the gold standard for evaluation of venogenic impotence...

..However, there has been no report investigating the eNOS G894T genetic susceptibility factor for both ED and BPH/LUTS...

..Thus, Rho kinase might be considered a novel target for the prevention of vasculogenic erectile dysfunction...

..Internal-pudendal angiography revealed multiple microaneurysms in the bilateral internal pudendal arteries, suggesting that nodal polyarteritis caused arterial erectile dysfunction...

..These results suggest that the impaired NO-mediated cavernosal relaxations after ischemia are closely related to the decreased NOS activity and the increased accumulation of L-NMMA and ADMA...

..To evaluate deep penile arterial flow after an intracavernosal injection with papaverine in patients with erectile dysfunction (ED)...

..The results in 90 patients suggest its selective use in the subset of nonresponding, nonleakers who have open cavernous arteries by Doppler, typically diabetics...

..The aim of this study was to evaluate the efficacy of sildenafil and success of treatment in particular etiological causes in erectile dysfunction lasting more than 3 months...

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..Finally, VEGF, whose induction has been identified in many other ischemic tissues, was not induced in corpus cavernous tissue of ligated rats...

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..Findings will continue to inform our understanding of bone fragility, bone loss, and osteoporosis. ..

..The primary outcome will be re-operation rates, repeat sling procedures (for failures), and other postoperative complications, stratified by high and low volume surgeons and hospitals. ..

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..We expect that our studies would lead to the detection of novel targets of antifibrotic therapy for penile and vascular diseases of considerable public health impact. ..

..Test the hypothesis that inhalation of MWCNT alters vascular reactivity via impared adenosine signaling. Specific Aim 4. Assess the role of endothiela nitric oxide, oxidative stress and vascular function in MWCNT cardiotoxicity. ..

..Specifically, it will help newly-diagnosed patients make more informed decisions regarding treatment and will help researchers design novel interventions to improve the quality of life of prostate cancer survivors. ..

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..Findings will continue to inform our understanding of bone fragility, bone loss, and osteoporosis. ..

..The long-term goal is to validate pre-clinically the use of these agents for medical treatment of erectile dysfunction associated with aging. ..

..If our hypothesis is correct, future studies may examine other modulators of this novel regulatory pathway and how potential alterations of this pathway may aid in treatment of erectile dysfunction. ..

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..Identification and characterization of transplants will be carried out with PCR analysis of the Y chromosome (male cells into female host), detailed histologic analysis and immunostaining for muscle cell markers. ..