Genomes and Genes
Summary: Study of mental processes and behavior of schizophrenics.
Publications328 found, 100 shown here
- Aberrant "default mode" functional connectivity in schizophreniaAbigail G Garrity
Trinity College, Hartford, CT, USA
Am J Psychiatry 164:450-7. 2007..It was hypothesized that the default mode network would show abnormal activation and connectivity in patients with schizophrenia...
- Recent advances in the phencyclidine model of schizophreniaD C Javitt
Department of Psychiatry, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, N Y
Am J Psychiatry 148:1301-8. 1991..The purpose of the present paper is to review recent advances in the study of the molecular mechanisms of PCP action and to describe their implications for the understanding of schizophrenic pathophysiology...
- Remission in schizophrenia: proposed criteria and rationale for consensusNancy C Andreasen
Department of Psychiatry, University of Iowa, Iowa City, Iowa, USA
Am J Psychiatry 162:441-9. 2005..These criteria should facilitate research and support a positive, longer-term approach to studying outcome in patients with schizophrenia...
- Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophreniaShitij Kapur
Clarke Division of the Centre for Addiction and Mental Health, 250 College St, Toronto, Ont M5T 1R8, Canada
Am J Psychiatry 160:13-23. 2003..The objective of this overview is to link the neurobiology (brain), the phenomenological experience (mind), and pharmacological aspects of psychosis-in-schizophrenia into a unitary framework...
- Neurocognitive deficit in schizophrenia: a quantitative review of the evidenceR W Heinrichs
Department of Psychology, York University, Toronto, Ontario, Canada
Neuropsychology 12:426-45. 1998..The results indicate that schizophrenia is characterized by a broadly based cognitive impairment, with varying degrees of deficit in all ability domains measured by standard clinical tests...
- Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophreniaSusan Whitfield-Gabrieli
Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Proc Natl Acad Sci U S A 106:1279-84. 2009..Hyperactivation (reduced task-related suppression) of default regions and hyperconnectivity of the default network may contribute to disturbances of thought in schizophrenia and risk for the illness...
- Emotional experience in patients with schizophrenia revisited: meta-analysis of laboratory studiesAlex S Cohen
Department of Psychology, Louisiana State University, 206 Audubon Hall Baton Rouge, LA 708080, USA
Schizophr Bull 36:143-50. 2010..Patients' ability to experience hedonic emotion is preserved, although they also show relatively strong, simultaneously occurring aversive emotion when processing laboratory stimuli considered by others to be pleasant or neutral...
- A meta-analysis of cognitive remediation in schizophreniaSusan R McGurk
Dartmouth Psychiatric Research Center, 105 Pleasant Street, Concord, NH 03301, USA
Am J Psychiatry 164:1791-802. 2007..This study evaluated the effects of cognitive remediation for improving cognitive performance, symptoms, and psychosocial functioning in schizophrenia...
- Mismatch negativity in schizophrenia: a meta-analysisDaniel Umbricht
University of Zurich, Department of Psychiatric Research, Psychiatric University Hospital Zurich, Switzerland
Schizophr Res 76:1-23. 2005..Many studies have reported abnormalities in the generation of MMN in schizophrenia. The objective of this study was to assess the magnitude of this deficit and associated factors...
- SchizophreniaKim T Mueser
New Hampshire Dartmouth Psychiatric Research Center, Department of Psychiatry, Dartmouth
Lancet 363:2063-72. 2004....
- The neurodevelopmental hypothesis of schizophrenia, revisitedS Hossein Fatemi
420 Delaware St SE, MMC 392, Minneapolis, MN 55455, USA
Schizophr Bull 35:528-48. 2009..We relate the neurodevelopmental model to a number of findings about schizophrenia. Finally, we also examine alternate explanations of the origin of schizophrenia including the neurodegenerative model...
- What does the PANSS mean?Stefan Leucht
Klinik für Psychiatrie und Psychotherapie der TU München Klinikum rechts der Isar, Ismaningerstr 22, 81675 Munchen, Germany
Schizophr Res 79:231-8. 2005..g. at least 20% or 50% reduction of the baseline score) are as yet unclear. We therefore compared the PANSS with simultaneous ratings of Clinical Global Impressions (CGI)...
- Perceiving is believing: a Bayesian approach to explaining the positive symptoms of schizophreniaPaul C Fletcher
University of Cambridge, Department of Psychiatry, Addenbrooke s Hospital, Hills Road, Cambridge, CB2 2QQ, UK
Nat Rev Neurosci 10:48-58. 2009..We suggest that it is possible to understand these symptoms in terms of a disturbed hierarchical Bayesian framework, without recourse to separate considerations of experience and belief...
- Anhedonia and emotional experience in schizophrenia: neural and behavioral indicatorsErin C Dowd
Department of Neuroscience Program, Washington University, St Louis, Missouri 631320, USA
Biol Psychiatry 67:902-11. 2010..Investigation of neural activity during emotional experience may help clarify whether symptoms of anhedonia more likely reflect alterations of in-the-moment hedonic experience or impairments in other aspects of goal-directed behavior...
- Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: a systematic reviewMax Marshall
Division of Psychiatry, University of Manchester, Manchester
Arch Gen Psychiatry 62:975-83. 2005..It has been postulated that a longer DUP leads to a poorer prognosis. If so, outcome might be improved through earlier detection and treatment...
- Duration mismatch negativity in biological relatives of patients with schizophrenia spectrum disordersPatricia T Michie
Centre for Clinical Research in Neuropsychiatry, University of Western Australia, Nedlands, Australia
Biol Psychiatry 52:749-58. 2002..The aim of this study was to determine whether first-degree relatives of schizophrenia patients show a similar reduction in MMN amplitude to duration deviants...
- Mismatch negativity in chronic schizophrenia and first-episode schizophreniaDean F Salisbury
Harvard Medical School, Department of Psychiatry, McLean Hospital, Belmont, MA, USA
Arch Gen Psychiatry 59:686-94. 2002..The MMN is reported to be reduced in patients with chronic schizophrenia. However, it is unknown whether MMN is reduced in patients with first-episode schizophrenia (at first hospitalization)...
- The neurodevelopmental model of schizophrenia: update 2005J L Rapoport
Child Psychiatry Branch, NIMH, NIH, Bethesda, MD 20892 1600, USA
Mol Psychiatry 10:434-49. 2005....
- Neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends on history of psychosis rather than diagnostic groupCarmen Simonsen
Department of Psychology, University of Oslo, 0317 Oslo, Norway
Schizophr Bull 37:73-83. 2011..We asked whether neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends more on history of psychosis than diagnostic category or subtype...
- The MATRICS Consensus Cognitive Battery, part 1: test selection, reliability, and validityKeith H Nuechterlein
Department of Psychology, UCLA Semel Institute for Neuroscience and Human Behavior, 300 Medical Plaza, Rm 2251, Los Angeles, CA 90095 6968, USA
Am J Psychiatry 165:203-13. 2008....
- The Brief Assessment of Cognition in Schizophrenia: reliability, sensitivity, and comparison with a standard neurocognitive batteryRichard S E Keefe
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, P O Box 3270, Durham, NC 27710, USA
Schizophr Res 68:283-97. 2004..76) and healthy controls (r=0.90). These psychometric properties make the BACS a promising tool for assessing cognition repeatedly in patients with schizophrenia, especially in clinical trials of cognitive enhancement...
- Facial emotion perception in schizophrenia: a meta-analytic reviewChristian G Kohler
Schizophrenia Research Center, Department of Psychiatry, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
Schizophr Bull 36:1009-19. 2010..0 (Borenstein M, Hedges L, Higgins J and Rothstein H. Comprehensive Meta-analysis. 2. Englewood, NJ: Biostat; 2005)...
- The functional significance of social cognition in schizophrenia: a reviewShannon M Couture
Department of Psychology, University of North Carolina at Chapel Hill, CB 3270, Davie Hall, Chapel Hill, NC 27599 3270, USA
Schizophr Bull 32:S44-63. 2006..These findings are discussed in light of treatment implications for schizophrenia...
- Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorderD Robinson
Department of Psychiatry, Hillside Hospital, Long Island Jewish Medical Center, Glen Oaks, NY 11004, USA
Arch Gen Psychiatry 56:241-7. 1999..We examined relapse after response to a first episode of schizophrenia or schizoaffective disorder...
- Goal representations and motivational drive in schizophrenia: the role of prefrontal-striatal interactionsDeanna M Barch
Department of Psychology, Washington University, Box 1125, One Brookings Drive, St Louis, MO, USA
Schizophr Bull 36:919-34. 2010....
- Toward the next generation of negative symptom assessments: the collaboration to advance negative symptom assessment in schizophreniaJack J Blanchard
Department of Psychology, University of Maryland, College Park, MD 20742 4411, USA
Schizophr Bull 37:291-9. 2011..The CAINS is being developed within a data-driven iterative process that seeks to ensure the measure's reliability, validity, and utility for both basic psychopathology and treatment development research...
- Cognitive improvement after treatment with second-generation antipsychotic medications in first-episode schizophrenia: is it a practice effect?Terry E Goldberg
Zucker Hillside Hospital, 7559 263rd Street, Glen Oaks, NY 11004, USA
Arch Gen Psychiatry 64:1115-22. 2007..However, none of these studies included healthy controls undergoing repeated testing to assess the possibility that improvements might reflect simple practice effects...
- Evidence for sensory prediction deficits in schizophreniaSukhwinder S Shergill
Institute of Neurology, University College London
Am J Psychiatry 162:2384-6. 2005..The authors test the hypothesis that patients with schizophrenia have defects in their ability to predict the sensory consequences of their actions...
- Comparison of patient and clinician perspectives in the assessment of antipsychotic medication adherenceCorrado Barbui
Section of Psychiatry and Clinical Psychology, Department of Medicine and Public Health, University of Verona, Verona, Italy
Psychopathology 42:311-7. 2009..Factors influencing patient and clinician perspectives in the assessment of medication adherence have never been compared...
- Thinking about the future cognitive remediation therapy--what works and could we do better?Til Wykes
Institute of Psychiatry, King s College London, London SE5 8AF, UK
Schizophr Bull 37:S80-90. 2011....
- Intranasal oxytocin reduces psychotic symptoms and improves Theory of Mind and social perception in schizophreniaCort A Pedersen
Department of Psychiatry CB 7160, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States
Schizophr Res 132:50-3. 2011..Our results suggest that, in addition to reducing classic psychotic symptoms, oxytocin may diminish certain social cognition deficits that are not improved by current antipsychotic medications...
- Mismatch negativity in schizophrenia: a family studyElvira Bramon
Institute of Psychiatry, PO Box 63, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
Schizophr Res 67:1-10. 2004..We investigated whether MMN is a potential marker of genetic vulnerability to schizophrenia by comparing MMN in a group of patients with schizophrenia, their unaffected relatives, and controls...
- Memory impairment in schizophrenia: a meta-analysisA Aleman
Psychological Laboratory, Utrecht University, The Netherlands
Am J Psychiatry 156:1358-66. 1999..In this article, the authors presented meta-analyses of the published literature on recall and recognition memory performance between patients with schizophrenia and normal comparison subjects...
- Connecting neurosis and psychosis: the direct influence of emotion on delusions and hallucinationsDaniel Freeman
Department of Psychology, Institute of Psychiatry, King s College London, University of London, Denmark Hill, London SE5 8AF, UK
Behav Res Ther 41:923-47. 2003..It is concluded that study needs to be made of the interaction between psychotic and neurotic processes in the development of delusions and hallucinations, and that neurotic and psychotic disorders may have common maintenance processes...
- Overlooking the obvious: a meta-analytic comparison of digit symbol coding tasks and other cognitive measures in schizophreniaDwight Dickinson
VISN 5 Mental Illness Research, Education and Clinical Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Arch Gen Psychiatry 64:532-42. 2007..In focusing on potentially localizable cognitive impairments, the schizophrenia meta-analytic literature has overlooked the largest single impairment: on digit symbol coding tasks...
- Schizophrenia and violence: systematic review and meta-analysisSeena Fazel
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, United Kingdom
PLoS Med 6:e1000120. 2009..In addition, we conducted a systematic review of investigations that reported on risk of homicide in individuals with schizophrenia and other psychoses...
- Impaired visual object recognition and dorsal/ventral stream interaction in schizophreniaGlen M Doniger
Cognitive Neurophysiology Laboratory, Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Arch Gen Psychiatry 59:1011-20. 2002..This study assessed the neural integrity of perceptual closure processes in schizophrenia by examining N(cl) generation. Generation of the preceding positive (P1) and negative (N1) ERP components was also examined...
- Reasoning, emotions, and delusional conviction in psychosisPhilippa A Garety
Department of Psychology, Institute of Psychiatry, King s College London, London, England
J Abnorm Psychol 114:373-84. 2005..Emotional states were not associated with the reasoning processes investigated. Anxiety, but not depression, made an independent contribution to delusional conviction...
- Complexity of prefrontal cortical dysfunction in schizophrenia: more than up or downJoseph H Callicott
Clinical Brain Disorders Branch, NIMH NIH, Bldg 10, Rm 4D 20, MSC 1389, Bethesda, MD 20892 1389, USA
Am J Psychiatry 160:2209-15. 2003..The authors' goal was to explore this phenomenon...
- Schizophrenia, consciousness, and the selfLouis A Sass
Department of Clinical Psychology, Center for Cognitive Science, Rutgers University, Piscataway, NJ, USA
Schizophr Bull 29:427-44. 2003..We conclude by discussing the possible relevance of this approach for identifying early schizophrenic symptoms...
- Ketamine-induced deficits in auditory and visual context-dependent processing in healthy volunteers: implications for models of cognitive deficits in schizophreniaD Umbricht
Psychiatric University Hospital, Department of Research, PO Box 68, Zurich 8029, Switzerland
Arch Gen Psychiatry 57:1139-47. 2000....
- Examining a cognitive model of persecutory ideation in the daily life of people with schizophrenia: a computerized experience sampling studyDror Ben-Zeev
Illinois Institute of Technology, Chicago, IL 60616, USA
Schizophr Bull 37:1248-56. 2011....
- The lifetime risk of suicide in schizophrenia: a reexaminationBrian A Palmer
Mayo Medical School, Department of Health Sciences Research, Rochester, Minn, USA
Arch Gen Psychiatry 62:247-53. 2005..The psychiatry literature routinely quotes a lifetime schizophrenia suicide prevalence of 10% based on 1 meta-analysis and 2 studies of chronic schizophrenics...
- Static and dynamic cognitive deficits in childhood preceding adult schizophrenia: a 30-year studyAbraham Reichenberg
Department of Psychology, Duke University, Durham, NC 27708, USA
Am J Psychiatry 167:160-9. 2010..about premorbid cognitive deficits: What is their developmental course? Do all premorbid cognitive deficits follow the same course? Are premorbid cognitive deficits specific to schizophrenia or shared by other psychiatric disorders?..
- Stability of mismatch negativity deficits and their relationship to functional impairments in chronic schizophreniaGregory A Light
Department of Psychiatry, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0804, USA
Am J Psychiatry 162:1741-3. 2005....
- Theory of mind in schizophrenia: meta-analysisMirjam Sprong
Department of Child and Adolescent Psychiatry, University Medical Centre, Heidelberglaan 100, HPA01 468, 3508 GA Utrecht, The Netherlands
Br J Psychiatry 191:5-13. 2007..Mentalising impairment (an impaired ability to think about people in terms of their mental states) has frequently been associated with schizophrenia...
- Social brain dysfunctions in schizophrenia: a review of neuroimaging studiesEric Brunet-Gouet
Service de Psychiatrie Adulte, Inserm ERI 0015, Hopital de Versailles, 177 route de Versailles, 78150 Le Chesnay, France
Psychiatry Res 148:75-92. 2006....
- Major self-mutilation in the first episode of psychosisMatthew Large
Schizophr Bull 35:1012-21. 2009..Acute psychosis, in particular first-episode schizophrenia, appears to be the major cause of MSM. Although MSM is extremely uncommon, earlier treatment of psychotic illness may reduce the incidence of MSM...
- Reduced frontotemporal functional connectivity in schizophrenia associated with auditory hallucinationsStephen M Lawrie
University Department of Psychiatry, Royal Edinburgh Hospital, Morningside Park, Edinburgh, Scotland, UK
Biol Psychiatry 51:1008-11. 2002..We used functional magnetic resonance imaging (fMRI) to investigate the frontotemporal disconnection hypothesis of schizophrenia...
- Dysfunction of ventral striatal reward prediction in schizophreniaGeorg Juckel
Department of Psychiatry, Charite University Medical Center, Campus Charite Mitte, CCM, Schumannstr 20 21, 10117 Berlin, Germany
Neuroimage 29:409-16. 2006..We used functional magnetic resonance imaging (fMRI) to assess the BOLD response in the ventral striatum of unmedicated schizophrenics during presentation of reward-indicating and loss-indicating stimuli...
- The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the efficacy of glutamatergic agents for negative symptoms and cognitive impairmentsRobert W Buchanan
Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD 21228, USA
Am J Psychiatry 164:1593-602. 2007..Agents that act at the glycine site of the N-methyl-D-aspartic acid (NMDA) glutamatergic receptor have been suggested as promising treatments for moderate to severe negative symptoms and cognitive impairments...
- The five-factor model of the Positive and Negative Syndrome Scale II: a ten-fold cross-validation of a revised modelMark van der Gaag
Parnassia Psychiatric Institute, Oude Haagweg 353, The Hague, The Netherlands
Schizophr Res 85:280-7. 2006..Complex means that symptoms can have multiple factor loadings, because they have multiple causes, not because they are ill defined. Stable means that the complex structure is found repeatedly in validations...
- Theory of mind and the role of IQ in chronic disorganized schizophreniaMartin Brune
Department of Psychiatry and Psychotherapy, Ruhr University of Bochum, Alexandrinenstr 1 3, D 44791 Bochum, Germany
Schizophr Res 60:57-64. 2003..Several studies have suggested a theory of mind (ToM) deficit in schizophrenic disorders. However, the role of interfering variables such as IQ, attention, memory, and severity of the disorder has remained ambiguous...
- Deviant matters: duration, frequency, and intensity deviants reveal different patterns of mismatch negativity reduction in early and late schizophreniaJuanita Todd
School of Psychology, University of Newcastle, Callaghan, Australia
Biol Psychiatry 63:58-64. 2008....
- Physiological responsivity to emotional pictures in schizophreniaRoelie J Hempel
Department of Psychiatry, Erasmus MC, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
J Psychiatr Res 39:509-18. 2005..Further studies will need to refine the dynamics of this stimulus category in relation to clinical state and medication effects...
- Facial emotion recognition in schizophrenia: intensity effects and error patternChristian G Kohler
Neuropsychiatry Section, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
Am J Psychiatry 160:1768-74. 2003..The authors used color photographs of emotional and neutral expressions to investigate recognition patterns of five universal emotions in schizophrenia...
- Theory of mind impairment in schizophrenia: meta-analysisEmre Bora
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Vic, Australia
Schizophr Res 109:1-9. 2009..Our review also suggests that future research should consider the potential moderating influence of IQ deficits on ToM performance in "remitted" patients, as well as the potential effects of residual symptoms...
- Facial expression and emotional face recognition in schizophrenia and depressionW Gaebel
Department of Psychiatry, Free University of Berlin, Federal Republic of Germany
Eur Arch Psychiatry Clin Neurosci 242:46-52. 1992..Differences in patterns of affect-related behavioral deficits may reflect dysfunctions in different underlying psychobiological systems...
- Antipsychotic combinations vs monotherapy in schizophrenia: a meta-analysis of randomized controlled trialsChristoph U Correll
The Zucker Hillside Hospital, Psychiatry Research, Glen Oaks, New York, NY 11004, USA
Schizophr Bull 35:443-57. 2009..Despite lacking evidence for its safety and efficacy, antipsychotic cotreatment is common in schizophrenia...
- Early-stage visual processing and cortical amplification deficits in schizophreniaPamela D Butler
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Arch Gen Psychiatry 62:495-504. 2005..Investigating magnocellular dysfunction in schizophrenia therefore permits evaluation of underlying etiologic hypotheses...
- Disrupted prediction-error signal in psychosis: evidence for an associative account of delusionsP R Corlett
Brain Mapping Unit, Department of Psychiatry, University of Cambridge, School of Clinical Medicine, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
Brain 130:2387-400. 2007..Our results support a neurobiological theory of delusion formation that implicates aberrant prediction-error signalling, disrupted attentional allocation and associative learning in the formation of delusional beliefs...
- Perceptual anomalies in schizophrenia: integrating phenomenology and cognitive neurosciencePeter J Uhlhaas
Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstrasse 46, Frankfurt am Main 60528, Germany
Schizophr Bull 33:142-56. 2007..Relationships of deficits in perceptual organization to cognitive and social dysfunction as well as the possible neurobiological mechanisms are discussed...
- MMN/P3a deficits in first episode psychosis: comparing schizophrenia-spectrum and affective-spectrum subgroupsManreena Kaur
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
Schizophr Res 130:203-9. 2011..First-episode psychosis (FEP) patients show reduced amplitudes of the 'MMN/P3a complex', but it is unclear whether this occurs across the FEP spectrum...
- Obesity as a risk factor for antipsychotic noncompliancePeter J Weiden
SUNY Health Sciences Center at Brooklyn, Brooklyn, NY 11203 2098, USA
Schizophr Res 66:51-7. 2004..It is, therefore, increasingly important to understand the impact of obesity and perceived weight problems on compliance with these medications...
- The impact of weight gain on quality of life among persons with schizophreniaDavid B Allison
Department of Biostatistics, Section on Statistical Genetics and Clinical Nutrition Research Center, Suite 327 Ryals Public Health Building, University of Alabama at Birmingham, 1665 University Avenue, Birmingham, AL 35294, USA
Psychiatr Serv 54:565-7. 2003..Clinicians should consider the effect of weight gain on quality of life when prescribing antipsychotics and should help patients adopt weight maintenance behaviors...
- Neurocognition in first-episode schizophrenia: a meta-analytic reviewRaquelle I Mesholam-Gately
Massachusetts Mental Health Center Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Department of Psychiatry, Harvard Medical School, MA, USA
Neuropsychology 23:315-36. 2009..Considerable heterogeneity of effect sizes across studies, however, underscores variability in manifestations of the illness and a need for improved reporting of sample characteristics to support moderator variable analyses...
- When top-down meets bottom-up: auditory training enhances verbal memory in schizophreniaR Alison Adcock
Duke University Department of Psychiatry and Center for Cognitive Neuroscience, University of California, San Francisco, CA, USA
Schizophr Bull 35:1132-41. 2009..We conclude with the observation that neuroplasticity-based cognitive training brings patients closer to physiological patterns seen in healthy participants, suggesting that it changes the brain in an adaptive manner in schizophrenia...
- What do we know about neuropsychological aspects of schizophrenia?Barton W Palmer
University of California, San Diego, 9500 Gilman Drive 0603V, La Jolla, CA 92093 0603, USA
Neuropsychol Rev 19:365-84. 2009....
- The 2009 schizophrenia PORT psychosocial treatment recommendations and summary statementsLisa B Dixon
VA Capitol Health Care Network Mental Illness Research Education and Clinical Center, Baltimore, MD, USA
Schizophr Bull 36:48-70. 2010....
- An fMRI study of facial emotion processing in patients with schizophreniaRaquel E Gur
Section of Neuropsychiatry, Department of Psychiatry, Gates Bldg 10th Floor, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104 4283, USA
Am J Psychiatry 159:1992-9. 2002..The authors evaluated cerebral blood flow response in schizophrenia patients during facial emotion processing to test the hypothesis of diminished limbic activation related to emotional relevance of facial stimuli...
- Emotion recognition via facial expression and affective prosody in schizophrenia: a methodological reviewJane Edwards
Departments of Psychology and Psychiatry, University of Melbourne, Early Psychosis Prevention and Intervention Center, Parkville, Victoria, Australia
Clin Psychol Rev 22:789-832. 2002..Emotion recognition research in schizophrenia should be informed by the general literature on emotion recognition with serious attention paid to methodological issues...
- Predicting response to atypical antipsychotics based on early response in the treatment of schizophreniaBruce J Kinon
Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
Schizophr Res 102:230-40. 2008..To test whether early onset of response to antipsychotic medications accurately predicts subsequent response in the treatment of patients with schizophrenia...
- Clinical, functional, and economic ramifications of early nonresponse to antipsychotics in the naturalistic treatment of schizophreniaHaya Ascher-Svanum
Eli Lilly and Company, Indianapolis, IN 46285, USA
Schizophr Bull 34:1163-71. 2008..This study assessed the predictive accuracy of early nonresponse to treatment and its clinical, functional, and economic ramifications in the naturalistic treatment of predominately chronic outpatients treated for schizophrenia...
- A randomized, controlled trial of computer-assisted cognitive remediation for schizophreniaDwight Dickinson
Mental Illness Research, Education and Clinical Center, VISN 5, VA Medical Center, Suite 6A BT MIRECC, 10 North Greene St, Baltimore, MD 21201, USA
Am J Psychiatry 167:170-80. 2010..The goal of the current study was to develop a broadly targeted computer-assisted cognitive remediation program and conduct a rigorous clinical trial in a large group of schizophrenia patients...
- Training of affect recognition in schizophrenia: Neurobiological correlatesUte Habel
University of Aachen, Aachen, Germany
Soc Neurosci 5:92-104. 2010..Specific training effects are seen to correspond with cerebral effects, probably reflecting a more efficient use of attentional, perceptual, or cognitive strategies...
- Clinical trial of wellness training: health promotion for severely mentally ill adultsLinda Chafetz
Department of Community Health Systems, University of California, San Francisco, California 94143 0608, USA
J Nerv Ment Dis 196:475-83. 2008..The WT group showed significantly better outcomes on the SF-36 physical functioning and general health scales. Findings affirm ability of SMI adults to benefit from active health promotion...
- A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophreniaYechiel Levkovitz
The Emotion Cognition Research Center, The Shalvata Mental Health Care Center, P O B 94 Hod Hasharon, Israel
J Clin Psychiatry 71:138-49. 2010..Other proposed mechanisms of action include effects of minocycline on the dopaminergic system and its inhibition of microglial activation...
- Clinical course and outcome of schizophrenia in a predominantly treatment-naive cohort in rural EthiopiaAtalay Alem
Medical Faculty, Department of Psychiatry, Addis Ababa University, Addis Ababa, Ethiopia
Schizophr Bull 35:646-54. 2009..Improving access to treatment may be the logical next step to improve outcome of schizophrenia in this setting...
- Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia?Sophia Vinogradov
Department of Psychiatry, School of Medicine, University of California San Francisco, California 94121, USA
Biol Psychiatry 66:549-53. 2009..We asked: would neuroplasticity-based cognitive training in schizophrenia result in increased serum BDNF?..
- Mouse pharmacological models of cognitive disruption relevant to schizophreniaJared W Young
Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA 92093 0804, USA
Neuropharmacology 62:1381-90. 2012..We conclude that the predictive validity of these models is currently difficult to assess and that much more needs to be done to develop useful mouse pharmacological models of cognitive disruption in schizophrenia...
- Negative symptoms and poor insight as predictors of the similarity between client and therapist ratings of therapeutic alliance in cognitive behavior therapy for patients with schizophreniaPaul H Lysaker
Roudebush VA Medical Center, Indianapolis, IN, USA
J Nerv Ment Dis 199:191-5. 2011..Higher overall therapist ratings were linked only to lower levels of disorganized symptoms among clients...
- Mismatch negativity (MMN) reduction in schizophrenia-impaired prediction--error generation, estimation or salience?Juanita Todd
School of Psychology, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia
Int J Psychophysiol 83:222-31. 2012..Possible interpretations of MMN studies in schizophrenia are linked to dominant theories about the neurobiology of the illness...
- World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia, Part 1: acute treatment of schizophreniaPeter Falkai
Department of Psychiatry and Psychotherapy, University of Saarland, Homburg Saar, Germany
World J Biol Psychiatry 6:132-91. 2005....
- Insight into illness, neurocognition and quality of life in schizophreniaL Boyer
Aix Marseille Univ, EA 3279 Research Unit, 13385 Marseille, France
Prog Neuropsychopharmacol Biol Psychiatry 36:271-6. 2012..The aim of this study was to assess the impact of insight into illness on self-reported quality of life (QoL) for patients with schizophrenia...
- Neurocognitive effects of first- and second-generation antipsychotic drugs in early-stage schizophrenia: a naturalistic 12-month follow-up studyXiaofeng Guo
Institute of Mental Health, The Second Xiangya Hospital, Central South University, Changsha, China
Neurosci Lett 503:141-6. 2011..Given that some neurocognitive improvement is attributable to a practice effect, any improvement is likely to be in the range of a small effect size...
- Distinct neural generators of sensory gating in schizophreniaTerrance J Williams
Department of Psychology, University of California, Los Angeles, Los Angeles, CA 90095 1563, USA
Psychophysiology 48:470-8. 2011..In each instance, the neural structure was found to account for unique variance in explaining the P50 ratio, along with some suggestion of DLPFC involvement in healthy subjects...
- Possible dysregulation of cortical plasticity in auditory verbal hallucinations-A cortical thickness study in schizophreniaClaudia van Swam
Dept of Psychiatric Neurophysiology, University Hospital of Psychiatry Bern, Bolligenstrasse 111, Bern, Switzerland
J Psychiatr Res 46:1015-23. 2012....
- The relation between objective and subjective domains of recovery among persons with schizophrenia-related disordersDavid Roe
Department of Community Mental Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel
Schizophr Res 131:133-8. 2011..Taken together, results are consistent with literature suggesting that clinical objective recovery is not synonymous with personal subjective recovery yet can be conceptualized as complementary...
- Error-related processing dysfunction in children aged 9 to 12 years presenting putative antecedents of schizophreniaKristin R Laurens
Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
Biol Psychiatry 67:238-45. 2010..This study examined whether ASz children display brain function abnormalities during error processing that are similar to those exhibited by adults with schizophrenia...
- Phenomenology of anomalous self-experience in early schizophreniaJosef Parnas
Cognitive Research Unit, Department of Psychiatry, Hvidore Hospital, University of Copenhagen, Copenhagen, Denmark
Compr Psychiatry 44:121-34. 2003..Psychopathological emphasis on these disorders may also help to integrate the search for the neurodevelopmental mechanisms in schizophrenia with developmental-psychological research on the ontogenesis of the self...
- Patients with schizophrenia demonstrate dissociation between affective experience and motivated behaviorErin A Heerey
Maryland Psychiatric Research Center, University of Maryland Baltimore, Baltimore, MD, USA
J Abnorm Psychol 116:268-78. 2007..These data suggest that the motivational deficits in schizophrenia reflect problems in the ability to translate experience into action...
- Impact of neurocognition on social and role functioning in individuals at clinical high risk for psychosisRicardo E Carrión
Department of Psychiatry Research, Zucker Hillside Hospital, NorthShore Long Island Jew ish Health System, Glen Oaks, NY 11004, USA
Am J Psychiatry 168:806-13. 2011..The authors assessed cognitive impairment in adolescents at clinical high risk for psychosis and examined its impact on social and role functioning...
- Impact of obesity on health-related quality of life in schizophrenia and bipolar disorderRonette L Kolotkin
Obesity and Quality of Life Consulting, Durham, North Carolina, USA
Obesity (Silver Spring) 16:749-54. 2008..This paper explores the health-related quality of life (HRQOL) of individuals with schizophrenia or bipolar disorder as a function of obesity status...
- Differentiation of schizophrenia patients from healthy subjects by mismatch negativity and neuropsychological testsYi Ting Lin
Department of Psychiatry, National Taiwan University Hospital Yun Lin Branch, Dou Liou City, Yun Lin, Taiwan
PLoS ONE 7:e34454. 2012....
- Divergent effects of two different doses of intranasal oxytocin on facial affect discrimination in schizophrenic patients with and without polydipsiaMorris B Goldman
Department of Psychiatry, Northwestern University, 446 East Ontario Suite 7 100, Chicago, IL 60611, USA
Psychopharmacology (Berl) 216:101-10. 2011..Intranasal oxytocin enhances facial affect discrimination in healthy subjects...
- Nicotine dependence in schizophrenia: clinical phenomena and laboratory findingsG W Dalack
Ann Arbor VA Medical Center, MI 48105, USA
Am J Psychiatry 155:1490-501. 1998..The goal of this report is to examine the potential implications of the high prevalence of smoking in schizophrenia for our understanding of this illness...
- Appreciating symptoms and deficits in schizophrenia: right posterior insula and poor insightLena Palaniyappan
Division of Psychiatry, University of Nottingham, A Floor, South Block, Queen s Medical Centre, Nottingham, NG7 2UH, United Kingdom
Prog Neuropsychopharmacol Biol Psychiatry 35:523-7. 2011..Abnormalities in interoceptive awareness and self-appraisal of emotional states may contribute to the loss of insight seen in schizophrenia...
- Empathic abilities in people with schizophreniaEmre Bora
Melbourne Neuropsychiatry Centre, Psychiatry Department of Melbourne University, Victoria, Australia
Psychiatry Res 160:23-9. 2008..Studies focusing on dysfunctional brain networks underlying empathy deficits and studies using more experimental measures of empathy should be helpful to unravel the true nature of the empathic failure in patients with schizophrenia...
- Social cognition, empathy and functional outcome in schizophreniaAmy Sparks
School of Psychiatry, University of New South Wales, Sydney NSW 2031, Australia
Schizophr Res 122:172-8. 2010..These findings have implications for the remediation of specific social cognitive deficits with respect to improving functional outcomes in schizophrenia...
- The amphetamine-induced sensitized state as a model of schizophreniaR E Featherstone
Section of Biopsychology, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8
Prog Neuropsychopharmacol Biol Psychiatry 31:1556-71. 2007..It is concluded that amphetamine sensitization likely impacts behaviour by altering the functioning of mesolimbic dopamine systems and prefrontal cortical function and can serve as a model of certain domains of schizophrenia...
- Reducing prefrontal gamma-aminobutyric acid activity induces cognitive, behavioral, and dopaminergic abnormalities that resemble schizophreniaTakeshi Enomoto
Department of Psychology and Brain Research Centre, University of British Columbia, 2136 West Mall, Vancouver, BC, Canada
Biol Psychiatry 69:432-41. 2011..However, a preclinical assessment of how suppression of prefrontal cortex GABA activity may reflect behavioral and cognitive pathologies observed in schizophrenia is forthcoming...
- Recovery in Schizophrenia: Longitudinal CourseMartin Harrow; Fiscal Year: 2007..unreadable] [unreadable]..
- Compensating for Cognitive Deficits in SchizophreniaDawn Velligan; Fiscal Year: 2005..abstract_text> ..
- Assessing social-cognitive deficits in schizophrenia.Shaun Eack; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Motivating Persons with Schizophrenia to ExerciseLORA BEEBE; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Course of Functional Deficits in Late-Life SchizophreniaPhilip Harvey; Fiscal Year: 2007..unreadable] [unreadable]..
- EARLY VISUAL PROCESSING IN SCHIZOPHRENIAMichael F Green; Fiscal Year: 2010....
- Clinical Ratings of Neurocognition (CRON)Joseph Ventura; Fiscal Year: 2007..The proposed developments are urgently needed to continue the momentum established by the MATRICS initiative, and facilitate regulatory acceptance and clinical awareness of new treatments for CIAS. [unreadable] [unreadable] [unreadable]..
- Stress Reactivity & Protective Factors in SchizophreniaJoseph Ventura; Fiscal Year: 2003..abstract_text> ..
- LANGUAGE PROCESSING IN SCHIZOPHRENIAGina Kuperberg; Fiscal Year: 2005..This training and research program will advance the candidate to the stage when she can establish herself as an independent investigator of the cognitive neuroscience of schizophrenia. ..
- Effectiveness Trial of Attention Shaping for SchizophreniaSteven M Silverstein; Fiscal Year: 2010....
- Dopaminergic Mechanisms of Reward in SchizophreniaJames Gold; Fiscal Year: 2007..If successful, the proposed work is designed to establish the conceptual foundation and preliminary data needed to support individual RO1 applications and a Translational Center. [unreadable] [unreadable]..
- Electrophysiological Correlates of Anhedonia in SchizophreniaWILLIAM HORAN; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Pleasant Events and Moods: A Time-Series AnalysisBrent Mausbach; Fiscal Year: 2006..The remaining participants will receive no feedback. All participants will receive a one-month follow-up to determine if those receiving detailed feedback experience fewer negative emotions and more positive emotions. ..
- WORK OUTCOME IN SCHIZOPHRENIA--BRAIN FUNCTION/STRUCTUREJames Gold; Fiscal Year: 2002..Abnormalities present in both good and poor outcome groups are arguably fundamental features of the illness. ..
- Interventions for Adherence to Oral Antipsychotic Medications in SchizophreniaDAWN IRENE VELLIGAN; Fiscal Year: 2010..The public health implications include effective disease management, maximizing long-term outcomes, and containing health care costs for schizophrenia. ..
- MEDICATION ADHERENCE AND OUTCOMES IN SCHIZOPHRENIADawn Velligan; Fiscal Year: 2004..Moreover, we hypothesize that compliance and functioning will return to baseline levels six months after discontinuation of treatment. ..
- Clozapine Treatment of Schizophrenic PatientsRobert Buchanan; Fiscal Year: 2006..The study will provide new information on the clinical utility of adjunctive risperidone in treatment-resistant patients who fail to adequately respond to clozapine. ..
- Advanced Centers for Interventions and Services ResearchRobert Buchanan; Fiscal Year: 2007....
- Comorbid Substance Abuse and Long-Term Health Outcomes in SchizophreniaDEANNA KELLY; Fiscal Year: 2008..This will be an important step for improving the lives of people with schizophrenia. [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
- Incentives Plus Bupropion for Smoking in SchizophrenicsJennifer Tidey; Fiscal Year: 2006..This study will provide significant information regarding the efficacy and feasibility of using a combination of contingency management and smoking pharmacotherapy to treat smoking in schizophrenics. [unreadable] [unreadable]..
- Cardiac-Related Mortality with Atypical AntipsychoticsDEANNA KELLY; Fiscal Year: 2005..This study is important as data on long-term health outcomes with atypical antipsychotics is lacking from the literature. ..
- PROSPECTIVE STUDY OF TARDIVE DYSKINESIA DEVELOPMENTJohn Kane; Fiscal Year: 2001..This strategy will provide a rapid and cost-effective answer to a critical question. ..
- Biological and Behavioral Mechanisms of Smoking in SchizophreniaJennifer Tidey; Fiscal Year: 2009..In turn, this information could be used to develop novel treatment strategies for these smokers. ..
- Cognitive Training and Enhanced Supported EmploymentMorris D Bell; Fiscal Year: 2010..FU, and 2 yr. FU will focus on cognitive and vocational outcomes, but will also include clinical status, quality of life and community function measures. Predictors of response to training will also be examined. ..
- Cognitive Behavioral Skills Training for SchizophreniaEric Granholm; Fiscal Year: 2009....
- The Effects of the Cannabinoid-1 Receptor Antagonist Rimonabant on Weight...Robert Buchanan; Fiscal Year: 2008..There should be direct evidence of efficacy and safety in these patients in order to provide truly effective treatments and further understanding of these disorders. [unreadable] [unreadable] [unreadable]..
- Innovative Training Methods for Improving Work OutcomeRobert Kern; Fiscal Year: 2004..abstract_text> ..
- Mapping Abnormal Neurodevelopment in SchizophreniaDeanna Barch; Fiscal Year: 2008..unreadable] ..
- PUPILLARY RESPONSES AND COGNITIVE AGING IN SCHIZOPHRENIAEric Granholm; Fiscal Year: 2004..Abnormal age-related decline on these measures would suggest an abnormally accelerated depletion of processing resources with aging in schizophrenia in late life and would support the neurodegeneration hypothesis. ..
- CLOZAPINE AND OLANZAPINE IN VIOLENT SCHIZOPHRENICSMenahem Krakowski; Fiscal Year: 2003..e. ability to utilize environmental feedback, impulsivity, and psychosis. Similar to the outcome measures, these symptoms will improve more with CLO than OLZ and more with OLZ than HAL. ..
- Genetics of Endophenotypes and SchizophreniaLarry Seidman; Fiscal Year: 2007..Findings of heritable deficits in specific measures will be used to guide the next generation of studies of the genetics of schizophrenia. ..
- Graduated Recovery Intervention for Early SchizophreniaDavid Penn; Fiscal Year: 2007..abstract_text> ..
- rTMS Clinical Trial for Auditory HallucinationsRALPH EDWARD HOFFMAN; Fiscal Year: 2010..This study will provide critical information regarding positioning strategies that optimize rTMS for AHs, as well as new insights regarding underlying pathophysiology. ..
- Folate in SchizophreniaDonald C Goff; Fiscal Year: 2010..This will be the first adequately-powered study to assess efficacy and identify predictors of response. ..
- Visual Processing in SchizophreniaPamela Butler; Fiscal Year: 2008..abstract_text> ..
- Family Study of Psychosis: Brain, Genes & Prenatal RiskLarry Seidman; Fiscal Year: 2005..Moreover, if rigorous definitions of PPCs are used, it will be possible to identify the specific types of PPCs associated with brain abnormalities, which can lead to prevention strategies. ..
- METHYLPHENIDATE TREATMENT OF ADHD IN CHILDREN WITH TSKenneth Gadow; Fiscal Year: 2004..To evaluate the impact of tic severity and comorbid internalizing and externalizing symptoms on clinical outcome, children with ADHD/+tics will be compared with an additional sample of children with ADHD/-tics at ages 11 and 16 years. ..
- Neural Network Models of LanguageRalph Hoffman; Fiscal Year: 2005..These findings will significantly advance our understanding of illness mechanisms in schizophrenia and direct future research aimed at developing more selective treatments that reverse these abnormalities. ..
- Antidepressant Augmentation of Late Life SchizophreniaJohn Kasckow; Fiscal Year: 2005....
- Neuroanatomy of Adult ADHD: An MRI Morphometric StudyLarry Seidman; Fiscal Year: 2006..abstract_text> ..
- SCHIZOPHRENIA--PSYCHOPATHOLOGY AND HETEROGENEITYLarry Seidman; Fiscal Year: 2004..Achievement of the second goal will help clarify which brain abnormalities in schizophrenic patients can be attributed to neurodevelop-mental events prior to onset and which are due to neurodegeneration after onset. ..
- Identifying molecular path of behavioural phenotype in schizophreniaL Hong; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Addiction and Subsequent Schizophrenia: A Link?Serge Sevy; Fiscal Year: 2008..abstract_text> ..
- Quality Life Among Youth with Craniofacial ConditionsDonald Patrick; Fiscal Year: 2004..S., and one in the United Kingdom. Adolescents and their parents will complete questionnaires at baseline, and gain at 1-2 year clinical follow-up. ..
- Cognitive Control Deficits and Formal Thought DisorderJOHN KERNS; Fiscal Year: 2005..abstract_text> ..
- DEVELOPMENTAL PROCESSES IN SCHIZOPHRENIC DISORDERSKeith H Nuechterlein; Fiscal Year: 2010..Potential predictors of response to these treatments will be evaluated. ..
- PEDIATRIC BIPOLAR COLLABORATIVE MOOD STABILZER TRAILRobert Findling; Fiscal Year: 2003..Lastly, this trial will provide descriptive information on the stability of acute phase response to monotherapy over a 16 week continuation phase. ..
- Neuroscience at the Boundaries of Neurology and PsychiatryNeal Swerdlow; Fiscal Year: 2006..unreadable] [unreadable]..
- Liability Markers for Deficit Schizophrenia?L Hong; Fiscal Year: 2004..We plan to use the preliminary data collected from this grant support to guide our full-scale search for phenotypic markers specifically associated with the liability for deficit schizophrenia and subsequent molecular genetic studies. ..
- Safety and Efficacy of Sertraline for Depression Congestive Heart FailureRanga Krishnan; Fiscal Year: 2007..Information collected in these follow-up contacts will include deaths, re-hospitalizations, cardiac events, functional status/quality of life measures, and level of depressive symptoms. ..
- MOLECULAR GENETICS OF HEROIN DEPENDENCEMing Tsuang; Fiscal Year: 2004..All genotypes will be available one year after they are generated, but no later than a year after the end of the funding period. We are submitting this proposal using the RO1 mechanism. ..
- INTERVENTION RESEARCH TRAINING FOR THE PSYCHOSESKeith Nuechterlein; Fiscal Year: 2004..D.s and the other half Ph.D.s. Trainees will be assigned to primary and secondary mentors who will supervise their training activities in an individualized research mentorship model. ..
- Frontal White Matter and Impulsivity in SchizophreniaMatthew Hoptman; Fiscal Year: 2007..A secondary aim will examine the relationship between FA and violence. Understanding the neural basis of impulsivity in schizophrenia would help identify at-risk patients and inform new treatment approaches. ..
- Metabolic Effects of Newer Antipsychotics in Older PtsDilip Jeste; Fiscal Year: 2009..abstract_text> ..
- Gender, Drinking Pattens, Health & Services SeekingCarla Green; Fiscal Year: 2004..Results from this study will advance our ability to develop gender-specific screening and intervention procedures that reduce adverse health consequences related to drinking patterns and other health behaviors. ..
- PARTIAL DOPAMINEAGONIST TREATMENT OF SCHIZOPHRENIACarol Tamminga; Fiscal Year: 2002..These data will predict and later help us to select optimal agonist intrinsic activity ior clinical testing for antipsychotic actvity, duration of therapeutic action, and side effects. ..
- Schizophrenia Biomarkers: Blood vs Brain Gene ExpressionMing Tsuang; Fiscal Year: 2006..abstract_text> ..
- Antipsychotic-Like Drug Effects of NeurotensinDavid Feifel; Fiscal Year: 2004....
- Work Rehabilitation For Older Adults With SchizophreniaElizabeth Twamley; Fiscal Year: 2007..abstract_text> ..
- Alternate Phenotypes of Substance AbuseMing Tsuang; Fiscal Year: 2006..The enormous health and financial costs of illicit drug abuse, both to the individual and to society, underscores the pressing need for such research. ..
- A Simple Measure for Studying Sensory Gating DeficitsNeal Swerdlow; Fiscal Year: 2007..abstract_text> ..
- Treatment Issues In Smokers with SchizophreniaMarc Steinberg; Fiscal Year: 2008..The plan will include important hands-on learning experiences, workshops, class work, attendance at national scientific conferences, and strong mentoring relationships. ..
- Ensuring Informed Consent Delivery As A ProcessBARTON PALMER; Fiscal Year: 2003..With this experience, we will then hold two 60 minute seminars (one at each facility) to disseminate the procedures developed for wider use by all researchers at each of the two facilities. ..
- Quality of Life of Overweight Youth: Multicultural ViewDonald Patrick; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
- Ethnicity and the Diagnosis of Affective IllnessMichael Gara; Fiscal Year: 2008..The final objective is to determine whether Latinos are at risk for similar problems in diagnostic assessments and treatment assignment. ..
- Quality of Somatic Care for the Seriously Mentally IIIRichard Goldberg; Fiscal Year: 2005..The overall goal of the educational/training program is to increase the methodological rigor of the proposed research and to facilitate the ability of the investigator to integrate these domains of research into further projects. ..
- Suicidal Behavior in Persons with Schizophrenia in ChinaMAOSHENG RAN; Fiscal Year: 2005..The results of this study will be crucial for further mental health intervention and prevention of suicide among persons with schizophrenia. ..
- TREATMENT OF NEGATIVE SYMPTOMS & COGNITIVE IMPAIRMENTSWilliam Carpenter; Fiscal Year: 2003..The study will provide new information on the efficacy of d- cyclosporine and glycine for both persistent primary and secondary negative symptoms and its effect on cognitive functioning. ..
- TREATMENT DECISION MAKING CAPACITY IN SCHIZOPHRENIABARTON PALMER; Fiscal Year: 2002..abstract_text> ..