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| neuropsychological testsSummarySummary: Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury. Top Publications
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Publications
Two-year follow-up of amyloid deposition in patients with Alzheimer's disease
Henry Engler
Uppsala Imanet AB, Imanet, GE Healthcare Uppsala University, Uppsala
Brain 129:2856-66. 2006..FDG imaging may be able to detect a stabilization of cerebral metabolism caused by therapy administered to patients with a clinical diagnosis of Alzheimer's disease...The unity and diversity of executive functions and their contributions to complex "Frontal Lobe" tasks: a latent variable analysis
A Miyake
Department of Psychology, University of Colorado at Boulder, 80309-0345, USA
Cogn Psychol 41:49-100. 2000..These results suggest that it is important to recognize both the unity and diversity of executive functions and that latent variable analysis is a useful approach to studying the organization and roles of executive functions...Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: an fMRI study
Serge A R B Rombouts
Department of Physics and Medical Technology, Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands
Hum Brain Mapp 26:231-9. 2005..These findings suggest that altered activity in the default mode network may act as an early marker for AD pathology...Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment
B Winblad
Division of Geriatric Medicine, Neurotec Department, Karolinska Institutet, 11382 Stockholm, Sweden
J Intern Med 256:240-6. 2004....Mild cognitive impairment as a diagnostic entity
R C Petersen
Department of Neurology, Alzheimer s Disease Research Center, Mayo Clinic College of Medicine, Rochester, MN, USA
J Intern Med 256:183-94. 2004..By refining the criteria for MCI, clinical trials can be designed with appropriate inclusion and exclusion restrictions to allow for the investigation of therapeutics tailored for specific targets and populations...The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment
Ziad S Nasreddine
Center for Clinical Research, Neurology Service, Hopital Charles LeMoyne, Quebec, Canada
J Am Geriatr Soc 53:695-9. 2005..To develop a 10-minute cognitive screening tool (Montreal Cognitive Assessment, MoCA) to assist first-line physicians in detection of mild cognitive impairment (MCI), a clinical state that often progresses to dementia...Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
Katya Rascovsky
Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, 3 West Gates, Philadelphia, PA 19104, USA
Brain 134:2456-77. 2011..Future studies will be needed to establish the reliability and specificity of these revised diagnostic guidelines...HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study
R K Heaton
University of California, San Diego, USA
Neurology 75:2087-96. 2010....Fitness effects on the cognitive function of older adults: a meta-analytic study
Stanley Colcombe
Beckman Institute and Department of Psychology, University of Illinois, Urbana, 61801, USA
Psychol Sci 14:125-30. 2003..The results are discussed in terms of recent neuroscientific and psychological data that indicate cognitive and neural plasticity is maintained throughout the life span...The Addenbrooke's Cognitive Examination Revised (ACE-R): a brief cognitive test battery for dementia screening
Eneida Mioshi
MRC Cognition and Brain Sciences Unit, University of Cambridge, Department of Clinical Neurosciences, Addenbrooke s Hospital, UK
Int J Geriatr Psychiatry 21:1078-85. 2006..There is a clear need for brief, but sensitive and specific, cognitive screening instruments as evidenced by the popularity of the Addenbrooke's Cognitive Examination (ACE)...Classification of primary progressive aphasia and its variants
M L Gorno-Tempini
Memory and Aging Center, Department of Neurology, UCSF, 350 Parnassus Avenue, Suite 905, San Francisco, CA 94143 1207, USA
Neurology 76:1006-14. 2011..Future collaborations will collect prospective data to identify relationships between each of these syndromes and specific biomarkers for a more detailed understanding of clinicopathologic correlations...Updated research nosology for HIV-associated neurocognitive disorders
A Antinori
Clinical Department, National Institute for Infectious Diseases Lazzaro Spallanzani, Instituto di Ricovero e Cura a Carattere Scientifico IRCCS, Rome, Italy
Neurology 69:1789-99. 2007..An algorithm is proposed to assist in standardized diagnostic classification of HAND...Anterior cingulate conflict monitoring and adjustments in control
John G Kerns
Department of Psychological Sciences, University of Missouri Columbia, Columbia, MO 65211, USA
Science 303:1023-6. 2004....Cognitive reserve
Yaakov Stern
Cognitive Neuroscience Division of the Taub Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, United States
Neuropsychologia 47:2015-28. 2009..It then focuses on methodologic issues that are important when attempting to elucidate the neural underpinnings of cognitive reserve using imaging studies, and reviews some of our group's work in order to demonstrate these issues...What is cognitive reserve? Theory and research application of the reserve concept
Yaakov Stern
G H Sergievsky Center, The Taub Institute, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
J Int Neuropsychol Soc 8:448-60. 2002..Epidemiologic and imaging data that help to develop and support the concept of reserve are presented...Cognitive dysfunction in HIV patients despite long-standing suppression of viremia
Samanta Simioni
Department of Neurology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
AIDS 24:1243-50. 2010..To determine the prevalence of cognitive complaints and HIV-associated neurocognitive disorders (HANDs) in a cohort of aviremic HIV-positive patients. To evaluate the relevance of the HIV dementia scale to detect HANDs...Aging gracefully: compensatory brain activity in high-performing older adults
Roberto Cabeza
Center for Cognitive Neurosciences, Duke University, B203 LSRC Building, Durham, North Carolina 27708, USA
Neuroimage 17:1394-402. 2002....Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD
R A Barkley
Department of Psychiatry, University of Massachusetts Medical Center, Worcester 01655, USA
Psychol Bull 121:65-94. 1997..Although the model is promising as a potential theory of self-control and ADHD, far more research is required to evaluate its merits and the many predictions it makes about ADHD...The activation of attentional networks
Jin Fan
Laboratory of Neuroimaging, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
Neuroimage 26:471-9. 2005..Overall, the fMRI results suggest that the functional contrasts within this single task differentially activate three separable anatomical networks related to the components of attention...Stop-signal inhibition disrupted by damage to right inferior frontal gyrus in humans
Adam R Aron
Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Cambridge CB2 2QQ, UK
Nat Neurosci 6:115-6. 2003Testing the efficiency and independence of attentional networks
Jin Fan
The Sackler Institute for Developmental Psychobiology, Department of Psychiatry, Weill Medical College of Cornell University, 1300 York Avenue, Box 140, New York, NY 10002, USA
J Cogn Neurosci 14:340-7. 2002..The ANT may also serve as an activation task for neuroimaging studies and as a phenotype for the study of the influence of genes on attentional networks...Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial
Nicola T Lautenschlager
WA Centre for Health and Ageing, University of Western Australia, Melbourne, Australia
JAMA 300:1027-37. 2008..Many observational studies have shown that physical activity reduces the risk of cognitive decline; however, evidence from randomized trials is lacking...Neurocognitive deficit in schizophrenia: a quantitative review of the evidence
R W Heinrichs
Department of Psychology, York University, Toronto, Ontario, Canada
Neuropsychology 12:426-45. 1998..The results indicate that schizophrenia is characterized by a broadly based cognitive impairment, with varying degrees of deficit in all ability domains measured by standard clinical tests...An application of prefrontal cortex function theory to cognitive aging
R L West
Department of Psychology, University of South Carolina, USA
Psychol Bull 120:272-92. 1996..I found the frontal lobe hypothesis to perform well, with the exception of an inability to account for age-related declines in item recall and recognition memory, possibly a result of age-related declines in medial temporal function...Meta-analysis of neurobehavioral outcomes in very preterm and/or very low birth weight children
Cornelieke Sandrine Hanan Aarnoudse-Moens
Division of Neonatology, Department of Pediatrics, Erasmus University Medical Centre Sophia Children s Hospital, Rotterdam, Netherlands
Pediatrics 124:717-28. 2009..We conducted a quantitative meta-analysis of studies published between 1998 and 2008 on academic achievement, behavioral functioning, and EF with the aim of providing aggregated measures of effect size for these outcome domains...Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review
Erik G Willcutt
Department of Psychology, University of Colorado, Boulder, Colorado 80309, USA
Biol Psychiatry 57:1336-46. 2005..Difficulties with EF appear to be one important component of the complex neuropsychology of ADHD...Neuropsychological clustering highlights cognitive differences in young people presenting with depressive symptoms
Daniel F Hermens
Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
J Int Neuropsychol Soc 17:267-76. 2011..Distinct neuropsychological profiling may help to predict later psychiatric outcomes and enhance individually-tailored early intervention strategies...Executive function and the frontal lobes: a meta-analytic review
Julie A Alvarez
Department of Psychology, Emory University, Atlanta, GA 30322, USA
Neuropsychol Rev 16:17-42. 2006..The paper concludes with a discussion of the implications of construing the validity of these neuropsychological tests in anatomical, rather than cognitive and behavioral, terms.Improving lesion-symptom mapping
Chris Rorden
Department of Communication Sciences and Disorders, University of South Carolina, SC 29208, USA
J Cogn Neurosci 19:1081-8. 2007..We also developed software to implement these tests (MRIcron), made freely available to the scientific community...Functional neuroanatomy of remote episodic, semantic and spatial memory: a unified account based on multiple trace theory
Morris Moscovitch
Department of Psychology, University of Toronto and Rotman Research Institute Baycrest Centre, Ontario, Canada
J Anat 207:35-66. 2005....Executive dysfunction in autism
Elisabeth L Hill
Department of Psychology, Goldsmiths College, University of London, Whitehead Building, New Cross, London SE14 6NW, UK
Trends Cogn Sci 8:26-32. 2004..It is concluded that more detailed research is needed to fractionate the executive system in autism by assessing a wide range of executive functions as well as their neuroanatomical correlates in the same individuals across the lifespan...Participation in cognitively stimulating activities and risk of incident Alzheimer disease
Robert S Wilson
Rush Alzheimer s Disease Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
JAMA 287:742-8. 2002..Frequent participation in cognitively stimulating activities has been hypothesized to reduce risk of Alzheimer disease (AD), but prospective data regarding an association are lacking...Developmental trajectory of number acuity reveals a severe impairment in developmental dyscalculia
Manuela Piazza
INSERM CEA Cognitive Neuroimaging Unit, Gif sur Yvette, France
Cognition 116:33-41. 2010..These results establish for the first time a clear association between dyscalculia and impaired "number sense", and they may open up new horizons for the early diagnosis and rehabilitation of mathematical learning deficits...Practice with sleep makes perfect: sleep-dependent motor skill learning
Matthew P Walker
Laboratory of Neurophysiology, Department of Psychiatry, Harvard Medical School, 74 Fenwood Road, Boston, Massachusetts 02115, USA
Neuron 35:205-11. 2002..This finding of sleep-dependent motor skill improvement may have important implications for the efficient learning of all skilled actions in humans...'Oops!': performance correlates of everyday attentional failures in traumatic brain injured and normal subjects
I H Robertson
Applied Psychology Unit, Rehabilitation Research Group, Addenbrooke s Hospital, Cambridge, U K
Neuropsychologia 35:747-58. 1997..We also report a highly significant correlation of -0.58 between SART performance and Glasgow Coma Scale Scores in the TBI group...Under-recruitment and nonselective recruitment: dissociable neural mechanisms associated with aging
Jessica M Logan
Department of Psychology, Washington University, St Louis, MO 63130, USA
Neuron 33:827-40. 2002..The former is reversible and potentially amenable to cognitive training; the latter may reflect a less malleable change associated with cognitive decline in advanced aging...A meta-analysis of cognitive remediation in schizophrenia
Susan R McGurk
Dartmouth Psychiatric Research Center, 105 Pleasant Street, Concord, NH 03301, USA
Am J Psychiatry 164:1791-802. 2007..This study evaluated the effects of cognitive remediation for improving cognitive performance, symptoms, and psychosocial functioning in schizophrenia...Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury
P Grandjean
Institute of Community Health, Odense University, Denmark
Neurotoxicol Teratol 19:417-28. 1997..At approximately 7 years of age, 917 of the children underwent detailed neurobehavioral examination. Neuropsychological tests included Finger Tapping; Hand-Eye Coordination; reaction time on a Continuous Performance Test; Wechsler ..Cognitive deficits in depression: possible implications for functional neuropathology
M P Austin
Mood Disorders Unit and Department of Liaison Psychiatry, Prince of Wales Hospital, Sydney, Australia
Br J Psychiatry 178:200-6. 2001..While depression is known to involve a disturbance of mood, movement and cognition, its associated cognitive deficits are frequently viewed as simple epiphenomena of the disorder...The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): preliminary clinical validity
C Randolph
Department of Neurology, Loyola University Medical Center, Maywood, IL, USA
J Clin Exp Neuropsychol 20:310-9. 1998..These data suggest that the RBANS is effective at both detecting and characterizing dementia of different etiologies...Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions
A Bechara
Department of Neurology, Division of Behavioral Neurology and Cognitive Neuroscience, University of Iowa College of Medicine, Iowa City, Iowa, USA
Brain 123:2189-202. 2000..This 'myopia for the future' in VM lesion patients persists in the face of severe adverse consequences, i.e. rising future punishment or declining future reward...Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials
Patrick J Smith
Box 3119, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Psychosom Med 72:239-52. 2010....Prism adaptation to a rightward optical deviation rehabilitates left hemispatial neglect
Y Rossetti
Service de Reeducation Neurologique, Hopital Henry Gabrielle, Hospices Civils de Lyon, France
Nature 395:166-9. 1998..the visual field to the right were improved on their manual body-midline demonstration and on classical neuropsychological tests. Unlike other physiological manipulations used to improve neglect, this improvement lasted for at least ..Altered functional connectivity in early Alzheimer's disease: a resting-state fMRI study
Kun Wang
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, People s Republic of China
Hum Brain Mapp 28:967-78. 2007..In addition, the results also suggest that AD may disturb the correlation/anti-correlation effect in the two intrinsically anti-correlated networks...When does age-related cognitive decline begin?
Timothy A Salthouse
Department of Psychology, University of Virginia, Charlottesville, VA 22904 4400, USA
Neurobiol Aging 30:507-14. 2009....Training of working memory in children with ADHD
Torkel Klingberg
Department of Neuropediatrics, Karolinska Institute, Stockholm, Sweden
J Clin Exp Neuropsychol 24:781-91. 2002..The results thus suggest that WM training potentially could be of clinical use for ameliorating the symptoms in ADHD...Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study
Constantine G Lyketsos
Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
JAMA 288:1475-83. 2002..Dementia and MCI are associated with neuropsychiatric symptoms in clinical samples. Only 2 population-based studies exist of the prevalence of these symptoms in dementia, and none exist for MCI...Memory enhancement in healthy older adults using a brain plasticity-based training program: a randomized, controlled study
Henry W Mahncke
Posit Science Corporation, 225 Bush Street, San Francisco, CA 94104, USA
Proc Natl Acad Sci U S A 103:12523-8. 2006..This study demonstrates that intensive, plasticity-engaging training can result in an enhancement of cognitive function in normal mature adults...Clock-drawing: is it the ideal cognitive screening test?
K I Shulman
Department of Psychiatry, University of Toronto, Sunnybrook and Women s College Health Sciences Centre, Ontario, Canada
Int J Geriatr Psychiatry 15:548-61. 2000..This review aims to synthesize the available evidence and assess the value of this screening test according to well-defined criteria...Diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease: a review
Terence C Chua
Neuropsychiatric Institute, Euroa Centre, Prince of Wales Hospital, Randwick, NSW, Australia
Curr Opin Neurol 21:83-92. 2008..To provide a comprehensive review of diffusion tensor imaging in evaluating microstructural changes in the spectrum of cognitive decline from ageing to Alzheimer's disease, in particular focusing on mild cognitive impairment...Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: the orbitofronto-striatal model revisited
Lara Menzies
Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
Neurosci Biobehav Rev 32:525-49. 2008....Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD
B C Dickerson
Department of Neurology, The Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Neurology 65:404-11. 2005..To use fMRI to investigate whether hippocampal and entorhinal activation during learning is altered in the earliest phase of mild cognitive impairment (MCI)...Dual tasking, gait rhythmicity, and Parkinson's disease: which aspects of gait are attention demanding?
Galit Yogev
Movement Disorders Unit, Neurology Department, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel
Eur J Neurosci 22:1248-56. 2005..Moreover, the associations between executive function and gait variability suggest that a decline in executive function in PD may exacerbate the effects of dual tasking on gait, potentially increasing fall risk...Normative data from the CANTAB. I: development of executive function over the lifespan
Cinzia R De Luca
Sunshine Hospital and Department of Psychiatry, University of Melbourne, Australia
J Clin Exp Neuropsychol 25:242-54. 2003..Declines in performance on all tasks were revealed for the 50-64 year old sample, providing support for the vulnerability of executive skills to normal aging...On inhibition/disinhibition in developmental psychopathology: views from cognitive and personality psychology and a working inhibition taxonomy
J T Nigg
Department of Psychology, Michigan State University, East Lansing 48824 1117, USA
Psychol Bull 126:220-46. 2000..Such an approach can clarify which inhibition distinctions are correct and which inhibition deficits go with which disorders...Response inhibition in the stop-signal paradigm
Frederick Verbruggen
Department of Psychology, Vanderbilt University, Nashville, TN 37203, USA
Trends Cogn Sci 12:418-24. 2008....Frequent amyloid deposition without significant cognitive impairment among the elderly
Howard Jay Aizenstein
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Arch Neurol 65:1509-17. 2008..in a clinically unimpaired elderly population, as assessed by Pittsburgh Compound B (PiB) positron emission tomography (PET) imaging, and its relationship to cognitive function, measured with a battery of neuropsychological tests.Effects of aerobic exercise on mild cognitive impairment: a controlled trial
Laura D Baker
Departments of Psychiatry and BehavioralScience, University of Washington School of Medicine, Seattle, Washington, USA
Arch Neurol 67:71-9. 2010..To examine the effects of aerobic exercise on cognition and other biomarkers associated with Alzheimer disease pathology for older adults with mild cognitive impairment, and assess the role of sex as a predictor of response...Functional specialization within rostral prefrontal cortex (area 10): a meta-analysis
Sam J Gilbert
University College London, UK
J Cogn Neurosci 18:932-48. 2006..These results point to considerable functional segregation within rostral prefrontal cortex...Frontal lobes and human memory: insights from functional neuroimaging
P C Fletcher
Research Department of Psychiatry, Cambridge University, Addenbrooke s Hospital, Cambridge, UK
Brain 124:849-81. 2001..We expect that the neuroimaging techniques will provide an important part of this enterprise...Using imagination to understand the neural basis of episodic memory
Demis Hassabis
Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London WC1N 3BG, United Kingdom
J Neurosci 27:14365-74. 2007..We suggest that additional brain regions are co-opted into this core network in a task-specific manner to support functions such as episodic memory that may have additional requirements...Prediction of psychosis by mismatch negativity
Mitja Bodatsch
Department of Psychiatry and Psychotherapy, University of Cologne, Germany
Biol Psychiatry 69:959-66. 2011..To this aim, mismatch negativity (MMN) was investigated in a sample clinically at high risk, comparing individuals with and without subsequent conversion to psychosis...Differential effects of early hippocampal pathology on episodic and semantic memory
F Vargha-Khadem
Cognitive Neuroscience Unit, Institute of Child Health, University College London Medical School, Wolfson Centre, Mecklenburgh Square, London WC1N 2AP, UK
Science 277:376-80. 1997..The findings provide support for the view that the episodic and semantic components of cognitive memory are partly dissociable, with only the episodic component being fully dependent on the hippocampus...Neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends on history of psychosis rather than diagnostic group
Carmen Simonsen
Department of Psychology, University of Oslo, 0317 Oslo, Norway
Schizophr Bull 37:73-83. 2011..We asked whether neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends more on history of psychosis than diagnostic category or subtype...Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial
Richard S E Keefe
Department of Psychiatry, John Umstead Hospital, Duke University Medical Center, Durham, NC 27710, USA
Arch Gen Psychiatry 64:633-47. 2007..The relative effect of the second-generation (atypical) antipsychotic drugs and older agents on neurocognition has not been comprehensively determined...Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory
D I Kaufer
Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
J Neuropsychiatry Clin Neurosci 12:233-9. 2000..The NPI-Q provides a brief, reliable, informant-based assessment of neuropsychiatric symptoms and associated caregiver distress that may be suitable for use in general clinical practice...Training of working memory impacts structural connectivity
Hikaru Takeuchi
Division of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University, Aoba ku, Sendai, Japan
J Neurosci 30:3297-303. 2010..Observed structural changes may underlie previously reported improvement of working memory capacity, improvement of other cognitive functions, and altered functional activity following working memory training...A voxel-based morphometry study of patterns of brain atrophy in ALS and ALS/FTLD
J L Chang
Department of Neurology, University of California San Francisco, CA, USA
Neurology 65:75-80. 2005..To investigate the patterns of MRI brain atrophy in patients with ALS with and without clinically evident frontotemporal lobar dementia (FTLD) using voxel-based morphometry (VBM)...Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108Met polymorphism
Jennifer H Barnett
Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
Biol Psychiatry 64:137-44. 2008..We conducted a meta-analysis of reported associations between the COMT Val158/108Met polymorphism and measures of memory and executive function...Prefrontal cortex and basal ganglia control access to working memory
Fiona McNab
Developmental Cognitive Neuroscience, Stockholm Brain Institute, Karolinska Institutet, MR Centrum, Stockholm, Sweden
Nat Neurosci 11:103-7. 2008....Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis
Sarah T Pendlebury
Stroke Prevention Research Unit, University Department of Clinical Neurology, John Radcliffe Hospital, Oxford, UK
Lancet Neurol 8:1006-18. 2009..We undertook this systematic review to assess the heterogeneity in the reported rates and to identify risk factors for pre-stroke and post-stroke dementia...Prodromal Alzheimer's disease: successive emergence of the clinical symptoms
Helene Amieva
Institut National de la Sante et de la Recherche Medicale, U897, France
Ann Neurol 64:492-8. 2008..Utilizing the long follow-up of the PAQUID study, we examined the emergence of the first clinical symptoms over a 14-year period of follow-up before the dementia phase of AD...Aerobic fitness is associated with hippocampal volume in elderly humans
Kirk I Erickson
Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15206, USA
Hippocampus 19:1030-9. 2009..Our results clearly indicate that higher levels of aerobic fitness are associated with increased hippocampal volume in older humans, which translates to better memory function...Leisure activities and the risk of dementia in the elderly
Joe Verghese
Einstein Aging Study, Albert Einstein College of Medicine, Bronx, NY 10461, USA
N Engl J Med 348:2508-16. 2003..It is unclear whether increased participation in leisure activities lowers the risk of dementia or participation in leisure activities declines during the preclinical phase of dementia...Neuropsychological performance in adult attention-deficit hyperactivity disorder: meta-analysis of empirical data
Claudia Schoechlin
Ludwig Maximilians University, Munich, Germany
Arch Clin Neuropsychol 20:727-44. 2005..b>Neuropsychological tests are important tools to quantify the attentional and/or cognitive deficits of patients compared to ..Functions of the left superior frontal gyrus in humans: a lesion study
Foucaud du Boisgueheneuc
Federation de Neurologie, Paris, France
Brain 129:3315-28. 2006..From a clinical perspective, this study provides new information on the impact of left SFG lesions on cognition that will be of use to neurologists and neurosurgeons...Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory
Susheel Vijayraghavan
Department of Neurobiology, Yale Medical School, 333 Cedar Street, New Haven, Connecticut 06520 8001, USA
Nat Neurosci 10:376-84. 2007..The evidence for an inverted U at the cellular level in behaving animals promises to bridge in vitro molecular analyses with human cognitive experience...Probing compulsive and impulsive behaviors, from animal models to endophenotypes: a narrative review
Naomi A Fineberg
Department of Psychiatry, National OCDs Specialist Centre, Hertfordshire Partnership NHS Foundation Trust, Queen Elizabeth II Hospital, Welwyn Garden City, Hertfordshire, UK
Neuropsychopharmacology 35:591-604. 2010..Targeted application of neurocognitive tasks, receptor-specific neurochemical probes, and brain systems neuroimaging techniques have potential for future research in this field...Theory of mind in patients with frontal variant frontotemporal dementia and Alzheimer's disease: theoretical and practical implications
Carol Gregory
Fulbourn Hospital, Cambridge, UK
Brain 125:752-64. 2002..This study supports the hypothesis that patients with fvFTD, but not those with Alzheimer's disease, are impaired on tests of ToM, and may explain some of the abnormalities in interpersonal behaviour that characterize fvFTD...Cognitive dysfunction in Parkinson's disease: the role of frontostriatal circuitry
Adrian M Owen
Medical Research Council Cognition and Brain Sciences Unit, Cambridge, United Kingdom
Neuroscientist 10:525-37. 2004..As a direct result, it has been possible to redefine impairments of executive function in Parkinson's disease more precisely in terms of the specific neuropsychological, neuroanatomical, and psychopharmacological mechanisms involved...Safety and cognitive effect of frontal DC brain polarization in healthy individuals
M B Iyer
Brain Stimulation Unit and Cognitive Neuroscience, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
Neurology 64:872-5. 2005..Activating effects on the frontal lobe might be beneficial for patients with frontal lobe disorders. This phase 1 study tested the safety of frontal DC, including its effects on frontal and other brain functions...Human medial frontal cortex mediates unconscious inhibition of voluntary action
Petroc Sumner
School of Psychology, Cardiff University, Tower Building, Park Place, Cardiff CF10 3AT, UK
Neuron 54:697-711. 2007..These findings imply that the SEF and SMA mediate automatic effector-specific suppression of motor plans. This automatic mechanism may contribute to the participation of these areas in the voluntary control of action...Perceptual deficits in amnesia: challenging the medial temporal lobe 'mnemonic' view
Andy C H Lee
MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge, UK
Neuropsychologia 43:1-11. 2005..These novel observations imply that the human MTL subserves both perceptual and mnemonic functions, with the hippocampus and perirhinal cortex playing distinct roles in spatial and object discrimination, respectively...Sensitivity and specificity of neuropsychological tests for mild cognitive impairment, vascular cognitive impairment and Alzheimer's disease
C A De Jager
Department of Pharmacology, University of Oxford, Oxford Project to Investigate Memory and Ageing, Radcliffe Infirmary Trust, Oxford
Psychol Med 33:1039-50. 2003..We designed a brief comprehensive neuropsychological test battery to help differentiate control subjects from patients with mild cognitive impairment (MCI) and dementia...Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials
Michael Grundman
Alzheimer s Disease Cooperative Study, Department of Neurosciences, University of California San Diego, 8950 Villa La Jolla Drive, Suite 227, La Jolla, CA 92037, USA
Arch Neurol 61:59-66. 2004..The Memory Impairment Study (MIS) is a multicenter clinical trial in patients with MCI designed to evaluate whether vitamin E or donepezil is effective at delaying the time to a clinical diagnosis of AD...The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort
Caroline H Williams-Gray
Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Forvie Site, Robinson Way, Cambridge, CB2 0PY, UK
Brain 132:2958-69. 2009..Our work suggests that the dementing process in Parkinson's disease is predictable and related to tau while frontal-executive dysfunction evolves independently with a more dopaminergic basis and better prognosis...Computerized working memory training improves function in adolescents born at extremely low birth weight
Gro C C Løhaugen
Department of Pediatrics and Rehabilitation, Sørlandet Hospital, Arendal, Norway
J Pediatr 158:555-561.e4. 2011..To evaluate the effect of a computerized working memory training program on both trained and non-trained verbal aspects of working memory and executive and memory functions in extremely low birth weight (ELBW; <1000 g) infants...Cognitive endophenotypes of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relatives
Emre Bora
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Vic, Australia
J Affect Disord 113:1-20. 2009..Our aim was to delineate neuropsychological deficits related to genetic susceptibility, illness process and iatrogenic factors in bipolar disorder (BD)...Disconnection as a mechanism for cognitive dysfunction in multiple sclerosis
R A Dineen
Department of Academic Radiology, Queen s Medical Centre, University of Nottingham, Nottingham, UK
Brain 132:239-49. 2009..This suggests that TBSS reveals functionally relevant tract injury underlying cognitive dysfunction in patients with multiple sclerosis...Elevated body mass index is associated with executive dysfunction in otherwise healthy adults
John Gunstad
Department of Psychology, Kent Hall, Kent State University, Kent, OH 44242, USA
Compr Psychiatry 48:57-61. 2007..Further research is needed to identify the etiology of these deficits and whether they resolve after weight loss...The human medial temporal lobe processes online representations of complex objects
Morgan D Barense
MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 2EF, United Kingdom
Neuropsychologia 45:2963-74. 2007....Long-lasting amelioration of visuospatial neglect by prism adaptation
Francesca Frassinetti
Dipartimento di Psicologia, Universita degli Studi di Bologna, Bologna, Italy
Brain 125:608-23. 2002..In conclusion, these findings show that prism adaptation is a productive way of achieving long-lasting improvements in neglect treatment...The role of cingulate cortex in the detection of errors with and without awareness: a high-density electrical mapping study
Redmond G O'Connell
Department of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
Eur J Neurosci 25:2571-9. 2007..These findings may be particularly important in the context of clinical studies in which a proper understanding of self-monitoring deficits requires an explicit measurement of error awareness...Influence of the COMT genotype on working memory and brain activity changes during development
Iroise Dumontheil
Neuroscience Department, Karolinska Institutet, Retzius vag 8, Stockholm, Sweden
Biol Psychiatry 70:222-9. 2011..Dopaminergic system changes during adolescence may lead to a reduction of basal dopamine levels, potentially affecting Met allele benefits during development...Neurocognitive profiles in bipolar I and bipolar II disorder: differences in pattern and magnitude of dysfunction
Carmen Simonsen
Department of Psychiatry, Ulleval University Hospital, and Institute of Psychology, University of Oslo, Oslo, Norway
Bipolar Disord 10:245-55. 2008..The aim of this study was to examine whether patients with bipolar I and bipolar II disorder have different neurocognitive profiles...The gateway hypothesis of rostral prefrontal cortex (area 10) function
Paul W Burgess
Institute of Cognitive Neuroscience and Psychology Department, University College London, London, WC1E 6BT, UK
Trends Cogn Sci 11:290-8. 2007..e. the 'thoughts in our head'). In this way, investigations into the functions of rostral PFC will reveal key new insights into how human and non-human mental abilities differ...Constructive episodic simulation of the future and the past: distinct subsystems of a core brain network mediate imagining and remembering
Donna Rose Addis
Department of Psychology, The University of Auckland, New Zealand
Neuropsychologia 47:2222-38. 2009....Neuroanatomy of hemispatial neglect and its functional components: a study using voxel-based lesion-symptom mapping
Vincent Verdon
Department of Psychology, University of Geneva, Geneva, Switzerland
Brain 133:880-94. 2010..study of 80 patients with a focal right hemisphere stroke, who were examined by a series of neuropsychological tests assessing different clinical manifestations of neglect...Identification of separable cognitive factors in schizophrenia
Keith H Nuechterlein
Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, USA
Schizophr Res 72:29-39. 2004..These separable cognitive dimensions also have broader relevance to future research aimed at understanding the nature and structure of core cognitive deficits in schizophrenia...Spatial memory deficits in patients with lesions to the right hippocampus and to the right parahippocampal cortex
V D Bohbot
Psychology Department, University of Arizona, Tucson, 85724, USA
Neuropsychologia 36:1217-38. 1998..Patients with lesions to the right parahippocampal cortex were impaired on this task with a 30 min delay, suggesting that the parahippocampal cortex itself may play an important role in spatial memory...Does anaesthesia cause postoperative cognitive dysfunction? A randomised study of regional versus general anaesthesia in 438 elderly patients
L S Rasmussen
Department of Anaesthesia, Center of Head and Orthopaedics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Acta Anaesthesiol Scand 47:260-6. 2003..We hypothesized that the incidence of POCD would be less with regional anaesthesia rather than general...
Research Grants
- Informed Consent in People with Multiple SclerosisMichael Basso; Fiscal Year: 2007..Individuals with M.S. and control participants will be administered a battery of standard neuropsychological tests that will emphasize executive function, memory, attention, and expressive and receptive language...
- COGNITIVE AND CEREBROVASCULAR SEQUELAE OF HYPERTENSIONJ Jennings; Fiscal Year: 2004..We and others have found that patients with essential hypertension have impaired performance on neuropsychological tests relative to age-matched controls...
- HEPATIC ENCEPHALOPATHY--NEUROPSYCHOLOGY & NEUROCHEMISTRYMichael Thomas; Fiscal Year: 2001..Although neuropsychological tests are the current standard for diagnosing SHE, the results are non-specific and reveal little about the ..
- Novel PET imaging agents for early diagnosis of plaque deposition in Alzheimer'sPadmakar Kulkarni; Fiscal Year: 2010..Ante-mortem diagnosis of Alzheimer's based on neuropsychological tests are inconclusive at early stages of the disease and clinical PET imaging with [18F]FDG is suboptimal for ..
- NEURAL RESPONSE TO INSULIN RESISTANCE TREATMENTSJASON J HASSENSTAB; Fiscal Year: 2013..The proposed study will use fMRI, biomarkers of metabolic functioning, and neuropsychological tests to examine changes in cognition and brain response in obese and sedentary middle aged adults undergoing ..
- 18F-Mefway PET for Human Aging and Alzheimer's DiseaseJogeshwar Mukherjee; Fiscal Year: 2013..18F-Mefway will be evaluated in well-characterized groups of control, MCI and AD subjects and results will be correlated with clinical outcome measures of 18F-FDG, MRI and neuropsychological tests.
- Brain Development, Behavior and Cognition in Pre- and Postnatal Cocaine ExposureTamara Duckworth Warner; Fiscal Year: 2010..of novel, cutting edge, state-of-the-art structural image analysis tools in conjunction with sophisticated neuropsychological tests to better understand the effects of cocaine on the structure and function of the developing human brain.
- Diabetes, Cognition and the BrainAntonio Convit; Fiscal Year: 2012..goal we will measure cognition (including memory and frontal lobe measures of performance) with standard neuropsychological tests, hippocampal volumes with validated and reliable MRI- based methods, and cerebral vascular reactivity ..
- A Follow-up of Children Enrolled in the Management of Myelomeningocele StudyELIZABETH ANN THOM; Fiscal Year: 2013..Cognitive function will be measured by a battery of neuropsychological tests. Motor level and function will be assessed by physical examination...
- fMRI and Cognition in Adolescent Cannabis UsersSusan F Tapert; Fiscal Year: 2010..of 90 adolescents recruited in project R21 DA15228 (PI: Tapert), and follow these 168 teens with the same neuropsychological tests, functional magnetic resonance imaging (FMRI;working memory, inhibition, and learning tasks), MRI (to ..
- Amyloid Plaque and Tangle Imaging in Alzheimer's Disease and Down SyndromeLinda D Nelson; Fiscal Year: 2010..Comparative neuropsychological tests with proven validity for people suffering from severe levels of cognitive impairment (e.g...
- Randomized Trial of IFCBT-HIVPI to Prevent HIV Among Non-Injection Drug UsersWilliam W Latimer; Fiscal Year: 2013..An assessment battery comprised of a standardized interview on HIV risk behavior, neuropsychological tests, tools to assess attitudes and behavior change skills targeted by IFCBT-HIVPI, drug and STI urine testing,..
- GABA-A alpha5 cognitive enhancers: pharmacology and neuropsychology in macaquesNancy A Ator; Fiscal Year: 2011....
- Ecological Momentary Assessment of Functioning in SchizophreniaEric L Granholm; Fiscal Year: 2013..The success of these efforts could ultimately lead to reduced disability in people with schizophrenia, which would have significant impact on patients and families, as well as broader societal and economic impact. ..
- PIB binding, hypometabolism, apathy and executive dysfunction in MCI and ADGAD ASHER MARSHALL; Fiscal Year: 2013..function, global function, functional assessments, behavioral assessments focusing on apathy, and neuropsychological tests focusing on executive function...
- Phase 2 Study of Glycomacropeptide vs. Amino Acid Diet for the Management of PKUDenise M Ney; Fiscal Year: 2013..assessed by food records, acceptability assessed by questionnaires, and cognitive function assessed by neuropsychological tests. The investigators expect that compared to the usual AA diet, the GMP diet will reduce plasma phe levels ..
- Imaging the Development of Memory Strategies in AgingCheryl J Aine; Fiscal Year: 2012..function with and without distracters, along with diffusion tensor imaging (DTI), MR morphometry, and neuropsychological tests to investigate links between: 1) WM integrity and system connectivity which are necessary for the ..
- Regional Brain Manganese Accumulation and Functional Consequences in WeldersXuemei Huang; Fiscal Year: 2013..fitters) with both retrospective and prospective environmental exposure measurements, neuropsychological tests, blood metal (Fe and Mn) assessment, and state-of-the-art MRI estimates of both Mn (with rapid T1 mapping)..
- fMRI and Cognition in Youth at Risk for AlcoholismSusan F Tapert; Fiscal Year: 2013..Pilot analyses will begin to look at normalization of these neural abnormalities, as some young adults transition out of heavy drinking. ..
- Characterizing Two Distinct ADHD Neurobiologies with fMRIMichael C Stevens; Fiscal Year: 2012..abstract_text> ..
- Vascular Risk and Cognition in a Multi-ethnic CohortClinton B Wright; Fiscal Year: 2013..factors and inflammatory markers is related to specific cognitive domains using a sensitive battery of neuropsychological tests. Conventional and novel risk factors will include cardiac diseases, hypertension and blood pressure, ..
- Mild Cognitive Impairment: Cerebrovascular Dysfunction and Exercise TrainingRong Zhang; Fiscal Year: 2012..Cognitive function will be assessed using a comprehensive battery of neuropsychological tests focused on the executive and memory function...
- COGNITIVE BENEFITS OF TREATING SLEEP APNEA IN DEMENTIASonia Ancoli-Israel; Fiscal Year: 2011..The long-term goal of this line of research is to find a new approach that might improve the quality of life, delay dementia, and reduce caregiver stress. ..
- NEUROPHYSIOLOGICAL ATTENTION MULTIPLEXING TESTALAN S GEVINS; Fiscal Year: 2010..Current static "frontal executive system" task derived from traditional paper and pencil neuropsychological tests have a number of limitations, foremost the inability to adapt in difficulty and provide a consistently ..
- Neuroanatomical Substrates of Aging & Cognitive DeclineGene E Alexander; Fiscal Year: 2010..and baseline and two year follow up assessments of cognitive function using a battery of standardized neuropsychological tests. We will test hypotheses using regional univariate and multivariate network analysis methods with voxel-..
- A Multi-Site Trial of a Cognitive Rehabilitation Intervention for Persons with MSAlexa K Stuifbergen; Fiscal Year: 2013..and feasible and had medium to large effects on the use of compensatory strategies and performance on neuropsychological tests of verbal memory...
- Videoconference CBT for Rural Breast Cancer Survivors with Cognitive ComplaintsRobert J Ferguson; Fiscal Year: 2012..on quality of life, anxiety about cognitive problems, functional wellbeing, and on brief telephone-based neuropsychological tests of memory at 3 time points: pre-treatment, post-treatment and 2-month follow-up...
- Adapt Integrated Family CBT into HIV Prevention Intervention for Pregnant WomenWilliam Latimer; Fiscal Year: 2009..The pilot test includes standardized interviews on HIV risk behavior and psychiatric disorders, neuropsychological tests, self-report tools, urine drug testing, and serologic tests of HIV and hepatitis A, B, and C viruses ..
- PET, APOE &the Preclinical Course of Alzheimer's DiseaseERIC MICHAEL REIMAN; Fiscal Year: 2012..measurements of gray matter density, cortical thickness and whole brain volume, clinical ratings and neuropsychological tests every two years in 35 54 homozygotes, 50 54 heterozygotes, and 75 54 non-carriers, further characterize ..
- Is mental disorder a preventable cause of age-related disease? The Dunedin Study.TERRIE EDITH MOFFITT; Fiscal Year: 2013..measures of sub-clinical health status that are known predictors of age-related diseases in later life: neuropsychological tests of memory and executive functions, the metabolic syndrome, immunological biomarkers, and shortened ..
- US-France Research Collaboration on Neuroimaging Studies of AlcoholismEDITH VIONI SULLIVAN; Fiscal Year: 2012..diffusion tensor imaging (DTI);and selective brain functions, measured with functional MRI (fMRI) and neuropsychological tests of component processes of cognition, memory, and motor abilities...
- Mechanisms of Spatial Cognitive Impairment in Neurodegenerative DiseaseKATHERINE LAUREL POSSIN; Fiscal Year: 2013..Joel Kramer, a neuropsychologist who is an international leader in the development of neuropsychological tests;Dr...
- Health Effects of PCB Exposure from Contaminated FishSusan L Schantz; Fiscal Year: 2010..Children will be assessed on a battery of neuropsychological tests that assess specific aspects of executive function including working memory, cognitive flexibility, ..
- Imaging Brain and Movement in ASDJeanne Townsend; Fiscal Year: 2010..Participants will complete a series of neuropsychological tests, functional assessments, MR and Diffusion Tensor Imaging and MoBI brain and movement imaging...
- Motor Control and Cerebellar Maturation in AutismMatthew W Mosconi; Fiscal Year: 2013..b>Neuropsychological tests of motor skill, as well as clinical neurological examinations of motor function, also will be ..
- Role of English Fluency in Spanish Neuropsychological PerformancePaula Suarez; Fiscal Year: 2010....
- QUESTIONABLE DEMENTIA: COURSE AND PREDICTORS OF OUTCOMEDavangere P Devanand; Fiscal Year: 2012..Accurate prediction of MCI conversion to AD will help identify patients who need early treatment, facilitate patient/family planning for their own future, and improve patient selection for clinical trials. ..
- Low-Burden Tools for Improving Prediction and Diagnosis of Cognitive Impairment.VALERIE FRANCES REYNA; Fiscal Year: 2010..g., the ApoE genotype), behavioral markers of impairment (e.g., neuropsychological tests), and clinical diagnoses of impairment...
- Perceptual, Cognitive, and Motor Rigidity in Parkinson's DiseaseMirella Díaz-Santos; Fiscal Year: 2013..The participants will be assessed for cognitive rigidity (neuropsychological tests of executive function including perseveration), motor rigidity (gait measures of relative phase between ..
- Qualitative analysis of cognitive functioning of prostate cancer survivors on ADTLISA MARIA WU; Fiscal Year: 2013..there is evidence that ADT may be associated with objectively-assessed cognitive impairment (assessed by neuropsychological tests), but there are also studies that note minimal or no impairments in ADT patients compared with healthy ..
- Complicated Grief in Older Adults: Physiological Substrates of Emotion RegulationMARY FRANCES O'CONNOR; Fiscal Year: 2011..The proposed research will assess neural activation, immune markers, and neuropsychological tests of attention and emotion regulation in older adults...
- Exercise &Overweight Children's CognitionPhillip D Tomporowski; Fiscal Year: 2012..abstract_text> ..
- Predicting Placebo Responses Across Disease StatesJon Kar Zubieta; Fiscal Year: 2012..variations in neurotransmitter systems and circuits involved will then be modeled by a combination of neuropsychological tests and the presence of common genetic polymorphisms regulating those regional networks...
- PAP adherence and real-world driving safety in OSAMatthew Rizzo; Fiscal Year: 2013..team of experts at UI will comprehensively assess 1) cognitive functions using standardized neuropsychological tests;2) physiologic indices of disease severity from laboratory based polysomnography (PSG);3) extended ..
- Loneliness and biomarkers of Alzheimer's disease in clinically normal elderlyNancy J Donovan; Fiscal Year: 2013..The goal of this study is to determine whether measures of loneliness are associated with sensitive neuropsychological tests and multi-modal neuroimaging biomarkers of preclinical AD in a cohort of clinically normal (CN) older ..
- Mnemonic Processing Deficits in Older Adults at Risk for Alzheimer's DiseasePaul E Gilbert; Fiscal Year: 2013..Specific Aim 1), examine relationships between performance on the experiments and standardized neuropsychological tests (Specific Aim 2), and characterize the performance of older adults, with and without the APOE E4 allele ..
- Imaging the effects of androgen deprivation therapy on cognitive functions in patHERTA HUEY AN CHAO; Fiscal Year: 2010..Changes in cognitive performance have been reported but results of previous studies using neuropsychological tests alone have been equivocal...
- STRESS AND INFLAMMATION IN THE PATHOPHYSIOLOGY OF LATE-LIFE DEPRESSIONYvette I Sheline; Fiscal Year: 2013..n=50), and assess participants pre- and post-treatment with peripheral and central cytokine levels, neuropsychological tests and brain resting state functional connectivity...
- Daily Functioning, Cognition, and Caregiver Burden in MCI PatientsLALEH JILL RAZANI; Fiscal Year: 2013..abstract_text> ..
- Molecular Studies of Cognition in Chronic AlcoholismJay W Pettegrew; Fiscal Year: 2010..b>Neuropsychological tests are used to assess abstract reasoning and problem solving, memory, attention, language, spatial abilities,..
- Pilot Explorations of Neurofeedback Issues in ADHDL Eugene Arnold; Fiscal Year: 2010..will include measures of symptoms, functional impairment, academic performance/achievement, and neuropsychological tests of attention, vigilance, and executive functioning...
- 2/2-Combined Oxytocin and CBSST for Social Function in People with SchizophreniaEric L Granholm; Fiscal Year: 2013..The study will provide critical preliminary data on the clinical utility of oxytocin + CBSST for the improvement of social function in people with schizophrenia. ..
- A brief iPad-based screening measure for HIV-associated neurocognitive disordersJOAN M SEVERSON; Fiscal Year: 2013..collected in the HIV+ participants, as well as examine the relationship between the iPad tests and common neuropsychological tests in individuals without brain dysfunction...
- MRI Structural and Functional Connectivity Changes in Temporal Lobe EpilepsyVictoria L Morgan; Fiscal Year: 2013..Furthermore, the proposed approach may be expanded and applied to other forms of focal epilepsy in both adults and children to increase the utilization of surgical treatment for these patients. ..
- 1/2-Combined Oxytocin and CBSST for Social Function in People with SchizophreniaRobert W Buchanan; Fiscal Year: 2013..The study will provide critical preliminary data on the clinical utility of oxytocin + CBSST for the improvement of social function in people with schizophrenia. ..
- Vascular Depression: Longitudinal FollowupYvette I Sheline; Fiscal Year: 2010..The proposal will provide important new data on neuroradiologic and neuropsychological factors contributing to recurrent or chronic depression in older individuals. ..
- Vascular Depression: Longitudinal ChangesWarren D Taylor; Fiscal Year: 2010..The proposal will provide important new data on neuroradiologic and neuropsychological factors contributing to recurrent or chronic depression in older individuals. ..
- Assessing Brain Function and Engagement in Older AdultsIzhak Shafran; Fiscal Year: 2013..Shafran's expertise in spoken language technology, a large clinical cohort monitored with extensive neuropsychological tests, an infrastructure for evaluating new technology, expertise in clinical psychology and epidemiology ..
- Neuropsychological Screening of OEF/OIF Veterans in VA Primary CareKaren H Seal; Fiscal Year: 2013..If successful, results from this study may be applied in translation to the VA primary care setting to improve VA's ability to efficiently and accurately assess and triage OEF/OIF veterans. ..
- ENGLISH AND SPANISH ASSESSMENT OF COGNITION IN ELDERLYDan M Mungas; Fiscal Year: 2012..b>Neuropsychological tests of cognitive abilities have long been used to measure changes in cognition related to diseases like ..
- Neurocognitive Deficits, Substance Use, and HIV Risk BehaviorSarit A Golub; Fiscal Year: 2010..A better understanding how of neurocognitive factors impact substance use and HIV risk is critical to the development, implementation, and adaptation of effective HIV prevention efforts. ..
- EFFECTS OF OMEGA-3 FATTY ACIDS ON COGNITIVE PERFORMANCEMatthew F Muldoon; Fiscal Year: 2012..This new, secondary outcome would entail administration of a battery of neuropsychological tests assessing working and general memory, psychomotor speed, attention and executive function at baseline and ..
- Visuospatial Rehabilitation after Right Hemisphere StrokePeii Chen; Fiscal Year: 2010..The significance of the proposed research is to establish effective treatments for visuospatial deficits in right hemisphere stroke survivors so that functional disability and cost of rehabilitation care will be reduced. ..
- Toward using comprehensive decision-making models in neuropsychological testingRoger Ratcliff; Fiscal Year: 2013..The eventual goal of the proposed research is the development of neuropsychological tests that can be used to assess the impacts on cognition of, for example, concussion, aging, and chemotherapy...
- Aging Brain, Cognition, and DopamineWilliam J Jagust; Fiscal Year: 2013..and that greater atrophy will be associated with higher dopamine synthesis and poorer performance on neuropsychological tests reflecting executive function...
- Neuropsychological & Thyroid Effects of Perfluorinated Compounds in Older AdultsEdward Fitzgerald; Fiscal Year: 2009....
- COGNITIVE AND NEUROIMAGING STUDY OF SICKLE CELL ANEMIAElias Melhem; Fiscal Year: 2001..The latter in combination with TCD studies will also elucidate the relationship between proximal characteristics observed by TCD and true end organ perfusion outlined by MR. ..
- DENTAL AMALGAMS AND NEUROPSYCHOLOGICAL FUNCTIONPam Factor Litvak; Fiscal Year: 1999..Occupational exposure also is associated with deficits in neuropsychological tests of memory and visuospatial ability and increased reports of subjective symptoms and disturbed mood...
- EARLY ABUSE AND CORTICOLIMBIC DEVELOPMENTMartin Teicher; Fiscal Year: 1999..b>Neuropsychological tests will assess for left vs right hemisphere functional impairment...
- HIV Dementia and Sensory Neuropathy in UgandaNed Sacktor; Fiscal Year: 2009....
- AIDS DEMENTIA--MOLECULAR AND CELLULAR MECHANISMSFloyd Bloom; Fiscal Year: 2000..In addition, these studies may illuminate other unexplained aspects of fundamental neuronal-glial-immune system interaction, the nature of brain resident microglia, and the basis for neuropsychiatric disorders of unknown origin. ..
- Effects of Prenatal Nutrition on Developmental Outcomes in the the Juvenile BabooTHAD BARTLETT; Fiscal Year: 2009....
- STN STIMULATION--DA TRANSPORTERS & OUTCOME IN PARKINSON'Andrew Newberg; Fiscal Year: 2004..Long-term outcome in each of these groups will be assessed with neuropsychological tests, clinical rating scales administered by research neurologists, and repeated measurements of dopamine ..
- Early brain development after prenatal "Ice" exposure: A Longitudinal MR studyLinda Chang; Fiscal Year: 2009..brain metabolite abnormalities on proton MR spectroscopy (1H MRS), along with decreased performance on neuropsychological tests. Our preliminary data also suggest that these children do not show appropriate age-related increases in ..