Research Topics
Genomes and Genes
| defense mechanismsSummarySummary: Unconscious process used by an individual or a group of individuals in order to cope with impulses, feelings or ideas which are not acceptable at their conscious level; various types include reaction formation, projection and self reversal. Top Publications
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Publications
How to bite your tongue without blowing your top: implicit evaluation of emotion regulation predicts affective responding to anger provocationIris B Mauss
Department of Psychology, University of Denver, Denver, CO 80208, USA
Pers Soc Psychol Bull 32:589-602. 2006..These findings suggest that implicit positive evaluation of emotion regulation is associated with successful, automatic, and physiologically adaptive down-regulation of anger...
Adaptive elements of aging: Self-image discrepancy, perfectionism, and eating problemsCarrie E Landa
Department of Psychology, Suffolk University, Boston, MA 02114, USA
Dev Psychol 43:83-93. 2007..Specific content domains of the real and ideal self-image and different facets of perfectionism showed distinctive age-related changes and differential relationships with eating pathology...
Elevated blood pressure and personality: a meta-analytic reviewR S Jorgensen
Department of Psychology, Syracuse University, New York 13244 2340, USA
Psychol Bull 120:293-320. 1996....
How does our brain constitute defense mechanisms? First-person neuroscience and psychoanalysisGeorg Northoff
Department of Psychiatry, Psychotherapy and Psychosomatics, University of Magdeburg, Magdeburg, Germany
Psychother Psychosom 76:141-53. 2007..between neuroscience and psychoanalysis, the neuronal processes underlying psychoanalytic constructs such as defense mechanisms remain unclear...
Avoidant coping as a predictor of mortality in veterans with end-stage renal diseaseErika J Wolf
National Center for PTSD, VA Boston Healthcare System, Boston, MA 02130, USA
Health Psychol 28:330-7. 2009..The aim of this study was to examine the role of active and avoidant coping strategies in predicting mortality in 61 veterans with end-stage renal disease...
Stress, depression and immunity: the role of defense and coping stylesM Olff
Department of Clinical Psychology, University of Groningen, Academic Hospital, The Netherlands
Psychiatry Res 85:7-15. 1999..Increasing the subject's abilities to cope with stress and to reduce the negative affect by psychological interventions may on the other hand have a beneficial effect on the immune system...
The effects of temperament, character, and defense mechanisms on grief severity among the elderlyKamel Gana
Department of Psychology, University of Bordeaux 2, 33000 Bordeaux, France
J Affect Disord 128:128-34. 2011....
Personality, personality disorders, and defense mechanismsP Cramer
Department of Psychology, Williams College, Williamstown, MA 01267, USA
J Pers 67:535-54. 1999..These personality prototypes were found to be related to the use of denial and projection, and especially to the immature manifestations of those defenses, in ways consistent with theory...
A study of stability and change in defense mechanisms during a brief psychodynamic investigationMartin Drapeau
, Adult Psychiatry Department of the University of Lausanne, Lausanne, Switzerland
J Nerv Ment Dis 191:496-502. 2003..Future studies will need to use designs that allow estimation of state changes while taking sufficient measurements to estimate potential changes in trait levels of defenses...
Defense mechanisms and suicide risk in major depressionShushan Hovanesian
Jamaica Hospital Medical Center, Department of Psychiatry, Jamaica, NY 11418, USA
Arch Suicide Res 13:74-86. 2009..The need to identify predictors that can be targets of therapy is of great importance. Coping styles and defense mechanisms have now been linked to suicide in numerous reports...
Long-term changes in defense styles with psychodynamic psychotherapy for depressive, anxiety, and personality disordersMichael Bond
Department of Psychiatry, Sir Mortimer B Davis Jewish General Hospital and McGill University, Quebec, Canada
Am J Psychiatry 161:1665-71. 2004....
Anxiety disorders: why they persist and how to treat themD M Clark
Department of Psychiatry, Warneford Hospital, University of Oxford, UK
Behav Res Ther 37:S5-27. 1999..Finally, ways of identifying the effective ingredients in cognitive therapy programmes are discussed...
The relationship between emotional intelligence and ego defense mechanismsJohn Pellitteri
Department of Educational and Community Programs, Queens College, City University of New York, Flushing 11367, USA
J Psychol 136:182-94. 2002..knowledge) and personality factors associated with adaptation, represented by the hierarchical model of defense mechanisms (M. Bond, S. Gardner, J. Christian, & J. Sigal, 1983)...
Do defense mechanisms vary according to the psychiatric disorder?Carolina Blaya
Post Graduate Program in Medical Sciences, Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
Rev Bras Psiquiatr 28:179-83. 2006The aim of this study was to evaluate the defense mechanisms used by depressive and anxious patients without comorbidities compared to those used by controls and to determine whether these patterns differ between diagnoses.
Psychological defenses of Danish medical studentsPeter la Cour
Institute of Public Health, University of Copenhagen, Panum Institute, Denmark
J Nerv Ment Dis 190:22-6. 2002..When defense mechanisms were labeled into mature, neurotic, and immature categories, there were no differences between the groups or ..
Defense mechanisms associated with borderline personality disorderMary C Zanarini
McLean Hospital, 115 Mill Street, Belmont, Massachusetts 02478, USA
J Pers Disord 23:113-21. 2009..They also had significantly higher scores than axis II comparison subjects on eight of the 19 defense mechanisms studied...
Emotional exhaustion and defense mechanisms in intensive therapy unit nursesAnna Regan
Birmingham Heartlands Hospital, Bordesley Green East, Birmingham 89 5SS, England
J Nerv Ment Dis 197:330-6. 2009..According to psychoanalytic theory, unconscious defense mechanisms may protect nurses from conscious awareness of work-related anxiety...
Hopelessness and suicide risk emerge in psychiatric nurses suffering from burnout and using specific defense mechanismsMaurizio Pompili
McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA
Arch Psychiatr Nurs 20:135-43. 2006..medicine/rehabilitation, and critical care/surgery wards to explore the correlations of level of burnout and defense mechanisms with hopelessness...
Adaptive mental mechanisms. Their role in a positive psychologyG E Vaillant
Department of Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Am Psychol 55:89-98. 2000..Last, evidence is offered to illustrate the validity of mature defenses and their contribution to positive psychology...
Predictors of mental distress in early adulthood: a five-year follow-up of 709 high-school studentsTerhi Aalto-Setälä
National Public Health Institute, Department of Mental Health and Alcohol Research, Mannerheimintie 166, FI 00300 Helsinki, Finland
Nord J Psychiatry 56:121-5. 2002..Males with low trait anxiety in adolescence had less distress. The results indicate trait anxiety as an important predictor of mental distress. Gender differences in other predictors suggest gender differences in coping...
Defense mechanisms and personality in depressionL S Mullen
Department of Psychiatry, College of Physicians and Surgeons, New York, New York, USA
Depress Anxiety 10:168-74. 1999..is the dynamic concept of character, that is, a predictable pattern of both adaptive and pathological defense mechanisms, and personality organization comprised of object relations, ego strengths, and superego development...
Differences between matched heterosexual and non-heterosexual college students on defense mechanisms and psychopathological symptomsMark A Biernbaum
Department of Child Development, California State University, Sacramento, CA 95819, USA
J Homosex 48:125-41. 2004Differences between heterosexual and non-heterosexual college students on measures of defense mechanisms and psychopathological symptoms were examined...
Initial psychometric properties of the experiences questionnaire: validation of a self-report measure of decenteringDavid M Fresco
Department of Psychology, 226 Kent Hall Annex, Kent State University, Kent, OH 44242, USA
Behav Ther 38:234-46. 2007..Findings from this series of studies offer initial support for the EQ as a measure of decentering...
Suicide Resilience Inventory-25: development and preliminary psychometric propertiesAugustine Osman
University of Northern Iowa, Department of Psychology, Cedar Falls, 50614 0505, USA
Psychol Rep 94:1349-60. 2004..Results of the two studies suggest the inventory is useful for assessing the construct of suicide resilience in terms of these three operationally defined dimensions...
Self-compassion and reactions to unpleasant self-relevant events: the implications of treating oneself kindlyMark R Leary
Department of Psychology and Neuroscience, Duke University, Durham, NC 27708, USA
J Pers Soc Psychol 92:887-904. 2007..In general, these studies suggest that self-compassion attenuates people's reactions to negative events in ways that are distinct from and, in some cases, more beneficial than self-esteem...
Urban adolescent stress and hopelessnessDana Landis
Department of Psychology, DePaul University, 2219 N Kenmore Ave, Chicago, IL 60614, USA
J Adolesc 30:1051-70. 2007..An analogous moderating effect was found for ruminative coping for girls. Ruminative coping also emerged as a mediator of the relation between uncontrollable stressors and hopelessness for girls...
Self-reported defence mechanisms as an outcome measure in psychotherapy: a study on the German version of the Defence Style Questionnaire DSQ 40Henning Schauenburg
Department of Psychosomatic and General Clinical Medicine, University of Heidelberg, Germany
Psychol Psychother 80:355-66. 2007..Our design did not permit an assessment of whether or not the change in defence mechanisms was due to the therapeutic treatment...
Temperament types are associated with weak self-construct, elevated distress and emotion-oriented coping in schizophrenia: evidence for a complex vulnerability marker?Michael Ritsner
Sha ar Menashe Mental Health Center, Mobile Post Hefer 38814, Israel
Psychiatry Res 128:219-28. 2004....
Using the impact of event scale to evaluate psychological response to being a phenylketonuria gene carrierCatherine Y Read
William F Connell School of Nursing at Boston College, Chestnut Hill, Massachusetts 02467, USA
J Genet Couns 13:207-19. 2004..As more tests become available for detecting the presence of disease-related genes, instruments such as the IES may prove useful in the evaluation of psychological responses to genetic information...
There is more to anger coping than "in" or "out"Wolfgang Linden
Department of Psychology, University of British Columbia, Vancouver, Canada
Emotion 3:12-29. 2003..Women reported use of a wider range of anger coping styles, especially more social support-seeking and more use of anger diffusion strategies than men...
Borderline attributionsRobert J Gregory
SUNY Upstate Medical University, Department of Psychiatry, 750 East Adams Street, Syracuse, NY 13210, USA
Am J Psychother 61:131-47. 2007....
[How do conflict and structure present themselves in relationships?]Tilman Grande
Klinik für Psychosomatische und Allgemeine Klinische Medizin der Universität Heidelberg, Germany
Z Psychosom Med Psychother 53:144-62. 2007..Furthermore, the connections between the OPD axes relationship, conflict, and structure are conceptualized...
Envy: one or many?Eduardo Laverde-Rubio
Int J Psychoanal 85:401-18. 2004..To answer the question posed in the title, the conclusion is that envy presents a central nucleus with different elaborative branches...
Cognitive content and process in eating-disordered patients with obsessive-compulsive featuresRachel Lawson
South Island Eating Disorders Service, Canterbury District Health Board, Princess Margaret Hospital, Private Bag 4710, Christchurch, New Zealand
Eat Behav 8:305-10. 2007..This study examined the schema-level cognitive content and processes that might explain the presence of compulsive behaviours among patients with eating disorders...
Adolescents' emotion regulation in daily life: links to depressive symptoms and problem behaviorJennifer S Silk
Western Psychiatric Institute and Clinic, USA
Child Dev 74:1869-80. 2003..g., denial) or involuntary engagement (e.g., rumination) was less effective in regulating negative affect, and greater use of these strategies was related to higher levels of depressive symptoms and problem behavior...
Unbearable shame, splitting, and forgiveness in the resolution of vengefulnessMelvin R Lansky
New Center for Psychoanalysis, Los Angeles, USA
J Am Psychoanal Assoc 55:571-93. 2007..Forgiveness is seen as the working through of that splitting and as an important feature in the working through of vengefulness...
Possible variances of blood urea nitrogen, serum potassium and phosphorus levels and interdialytic weight gain accounted for compliance of hemodialysis patientsJiro Takaki
Department of Psychosomatic Medicine, Tokyo University Hospital, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, 113 8655, Tokyo, Japan
J Psychosom Res 55:525-9. 2003....
Cognitive schemas, defence mechanisms and post-traumatic stress symptomatologyJason P Price
South Tees Hospitals NHS Trust, Middlesbrough, UK
Psychol Psychother 80:343-53. 2007..To identify specific ego defences and core schemas involved in post-traumatic stress disorder (PTSD) symptomatology...
Worry and use of coping strategies among older and younger adultsSandra Hunt
Department of Psychology, University of Massachusetts at Amherst, Tobin Hall, Amherst, MA 01003, USA
J Anxiety Disord 17:547-60. 2003..Explanations for these differences are discussed along with implications for the function of worry across the life span...
The cognitive nature of forgiveness: using cognitive strategies of primary appraisal and coping to describe the process of forgivingJohn Maltby
University of Leicester, Leicester, UK
J Clin Psychol 63:555-66. 2007..Crucial differences in the ways that men and women appraise and cope with situations involving forgiveness are discussed...
A cluster analysis of perfectionism among competitive athletesGuillaume Martinent
Centre de Recherche et d Innovation sur le Sport, UFRSTAPS, Universite Claude Bernard Lyon 1, 27 29 Boulevard du 11 Novembre, 69622 Villeurbanne, France
Psychol Rep 99:723-38. 2006..The importance of considering all dimensions of perfectionism simultaneously when examining the functional nature of this construct in sport is discussed...
Distress tolerance in the eating disordersEmma Corstorphine
Outpatient Eating Disorders Service, South West London and St George s Mental Health NHS Trust, Harewood House, Springfield University Hospital, London SW17 7DJ, UK
Eat Behav 8:91-7. 2007..This study aimed to develop a measure of distress tolerance, and to validate it clinically with the eating disorders...
Falling forever: the price of chronic shockKathleen A Adams
Int J Group Psychother 56:127-72. 2006..The ability to recognize subtle dissociative states is a valuable tool in the repertoire of the group psychotherapist...
Seeing and being seen: narcissistic pride and narcissistic humiliationJohn Steiner
Int J Psychoanal 87:939-51. 2006..An understanding of the mechanisms involved seemed to enable some development to proceed...
Development of a measure to assess invalidating childhood environments in the eating disordersVictoria Mountford
South West London and St George s Mental Health NHS Trust, London, UK
Eat Behav 8:48-58. 2007..It also investigated the relationship between childhood experiences, levels of distress tolerance and eating pathology...
Self-regulatory processes defend against the threat of death: Effects of self-control depletion and trait self-control on thoughts and fears of dyingMatthew T Gailliot
Department of Psychology, Florida State University, Tallahassee, FL 32306 1270, USA
J Pers Soc Psychol 91:49-62. 2006..These results suggest that self-regulation is a key intrapsychic mechanism for alleviating troublesome thoughts and feelings about mortality...
Sense of reality, reality testing and reality processing in borderline patientsLuis Claudio Figueiredo
Int J Psychoanal 87:769-87. 2006....
Psychological adjustment following diagnosis and treatment of cancer: an examination of the moderating role of positive and negative emotional expressivityPhillip J Quartana
Department of Psychology, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, Illinois 60064, USA
J Behav Med 29:487-98. 2006..These findings underscore the importance of examining the impact of individual differences in negative, as well as positive, emotional expression on cognitive processing and psychological adjustment...
OstracismKipling D Williams
Department of Psychological Sciences, Purdue University, West Lafayette, Indiana 47907, USA
Annu Rev Psychol 58:425-52. 2007..Available research on chronic exposure to ostracism appears to deplete coping resources, resulting in depression and helplessness...
Latent variable analysis of coping, anxiety/depression, and somatic symptoms in adolescents with chronic painBruce E Compas
Department of Psychology and Human Development, Vanderbilt University, Nashville, TN 37203, USA
J Consult Clin Psychol 74:1132-42. 2006..Implications for understanding child and adolescent coping with pain are highlighted...
An experimental manipulation of retrospectively defined earned and continuous attachment securityGlenn I Roisman
Department of Psychology, University of Illinois at Urbana Champaign, IL 61820, USA
Child Dev 77:59-71. 2006..Induced mood was unrelated to security versus insecurity...
Discrepancies between implicit and explicit self-esteem: implications for narcissism and self-esteem instabilityVirgil Zeigler-Hill
Department of Psychology, University of Southern Mississippi Hattiesburg, MS 39406, USA
J Pers 74:119-44. 2006..Second, participants with high explicit self-esteem and high implicit self-esteem displayed the most stable self-esteem. Findings are discussed in terms of secure and fragile high self-esteem...
Treating the "wise baby"Judith E Vida
Judith E Vida, 301 S Fair Oaks Ave, Suite 406A, Pasadena, CA 91105, USA
Am J Psychoanal 65:3-12. 2005....
Self-regulation and recovery: approaching an understanding of the process of recovery from stressJürgen Beckmann
University of Potsdam, Department of Sport Science, Germany
Psychol Rep 95:1135-53. 2004..g., self-determination, self-motivation, emotion control, whereas state orientation furthers a perseverance of stress through rumination and self-discipline...
Psychosocial factors associated with perceived disease severity in patients with chronic hepatitis C: relationship with information sources and attentional coping stylesAymery Constant
Laboratoire de Psychologie de la Santé EA 3662, Universite Victor Segalen Bordeaux 2, France
Psychosomatics 46:25-33. 2005..These results suggest that information processing and psychological features play a key role in the way patients with chronic hepatitis C perceive their disease...
Stress, appraisal, and coping: a comparison of HIV-infected women in the pre-HAART and HAART erasKarolynn Siegel
Center for the Psychosocial Study of Health and Illness, Mailman School of Public Health, Columbia University, 100 Haven Avenue, Suite 6A, New York, NY 10032, USA
J Psychosom Res 58:225-33. 2005..It has been widely suggested that highly active antiretroviral therapy (HAART) has improved the psychosocial aspects of living with HIV/AIDS...
Perceptions of stress and coping strategies among adults with mild mental retardation: insight into psychological distressSigan L Hartley
Department of Psychology, University of Wyoming, Laramie, WY 82071, USA
Am J Ment Retard 110:285-97. 2005..Decreasing opportunities for stress and increasing accurate perceptions of control and subsequently active coping may reduce psychological distress among people with mild mental retardation...
Cognitive processes underlying coping flexibility: differentiation and integrationCecilia Cheng
Division of Social Science, Hong Kong University of Science and Technology, Kowloon, Hong Kong
J Pers 73:859-86. 2005..Individuals who cope more flexibly display a greater extent of differentiation and integration than do those who cope less flexibly. These findings are translated into strategies for stress management workshops...
Variations on the concept of traumatism: traumatism, traumatic, traumaThierry Bokanowski
Int J Psychoanal 86:251-65. 2005..The author illustrates his hypotheses with a clinical example...
Psychodynamic assessment of changes in children with autism under psychoanalytic treatmentGeneviève Haag
Department of Child Psychiatry, 154 rue de Chatillon, F 35000 Rennes, France
Int J Psychoanal 86:335-52. 2005..First, the authors describe the principal psychoanalytic approaches to autism and reflect on the links possible with non-psychoanalytic work...
Les Enfants de Duplessis: perspectives on trauma and resiliencyJon A Shaw
Division of Child and Adolescent Psychiatry and Behavioral Sciences, University of Miami, Miller School of Medicine, USA
Psychiatry 69:328-32. 2006
Confirmatory factor analysis of a short form of the Coping Inventory for Stressful SituationsSharon L Cohan
San Diego State University, and VA San Diego Healthcare System, CA, USA
J Clin Psychol 62:273-83. 2006..It was concluded that the task-oriented and emotional scales have potential as measures of two types of responses to routine stressors...
Resolving attachment injuries in couples using emotionally focused therapy: steps toward forgiveness and reconciliationJudy A Makinen
Department of PsychologyUniversity of Ottawa, Ottawa, ON, Canada
J Consult Clin Psychol 74:1055-64. 2006..They also showed significant improvements in dyadic satisfaction and forgiveness than nonresolved couples. The results support the attachment injury resolution model and suggest that resolution during EFT is beneficial to couples...
A motivational analysis of defensive pessimism and self-handicappingAndrew J Elliot
Department of Clinical and Social Sciences in Psychology, University of Rochester, NY 14627, USA
J Pers 71:369-96. 2003..Issues regarding the functional nature of the two cognitive strategies are discussed...
Posttraumatic stress disorder and posttraumatic growth among Israeli ex-powsZahava Solomon
Adler Research Center, Tel Aviv University, Ramat Aviv, Israel
J Trauma Stress 20:303-12. 2007..In addition, both linear and quadratic associations between PTSD and PTG were found. The authors discuss some unresolved issues related to assessment of PTG and salutary outcomes, and outline directions for future research...
The dynamics of empirically derived factors in the therapeutic relationshipEric J Nuetzel
St Louis Psychoanalytic Institute, MO 63124, USA
J Am Psychoanal Assoc 55:1321-53. 2007..Results indicate that the therapeutic alliance, transference, and resistance are central components of the psychotherapeutic relationship, which in turn predict the ongoing life experience of the patient...
Day-to-day body-image states: prospective predictors of intra-individual level and variabilityJonathan A Rudiger
Virginia Consortium Program in Clinical Psychology, Virginia Beach, VA, United States
Body Image 4:1-9. 2007..Implications and future directions for research are discussed...
Coping by redefinition: cognitive appraisals in mothers of children with autism and children without autismBelgin Tunali
University of Houston, Texas, USA
J Autism Dev Disord 32:25-34. 2002..Moreover, mothers of children with autism who showed these characteristics had the greatest life satisfaction overall...
Longitudinal effects of hope on depression and anxiety: a latent variable analysisRandolph C Arnau
Department of Psychology, The University of Southern Mississippi, Hattiesburg 39406, USA
J Pers 75:43-64. 2007..In both cases, neither depression nor anxiety demonstrated any longitudinal effects on either the Agency or Pathways components of hope. Implications of these findings are discussed, along with potential directions for future research...
The influence of extreme traumatization on body, mind and social relationsBent Rosenbaum
University of Copenhagen
Int J Psychoanal 88:1527-42. 2007..Extreme trauma causes disturbances in each of these dimensions. The authors present clinical material from a traumatized refugee to illustrate the analytic work...
Relation of perfectionism with athletes' burnout: further examinationLung Hung Chen
National Taiwan Sport University, Taoyuan County
Percept Mot Skills 106:811-20. 2008..In terms of practical implications in intervention work, coaches and sport psychologists should try to reduce athletes' maladaptive perfectionism and increase adaptive perfectionism...
Perceived parental psychological control and eating-disordered symptoms: maladaptive perfectionism as a possible intervening variableBart Soenens
Department of Psychology, Ghent University, Belgium
J Nerv Ment Dis 196:144-52. 2008..Directions for future research on controlling parenting, perfectionism, and ED are outlined...
Analysis of lifestyle and behavioral characteristics in Meniere's disease patients and a control populationM Takahashi
Department of Otolaryngology, Tokai University School of Medicine, Kanagawa-ken, Japan
Acta Otolaryngol 121:254-6. 2001..A tendency towards stress-causative behavioral characteristics in Meniere's disease patients may be important in the genesis of endolymphatic hydrops...
Understanding adolescent worry: the application of a cognitive modelNina Laugesen
Centre for Research in Human Development, Department of Psychology, Concordia University, Montreal, Quebec, Canada
J Abnorm Child Psychol 31:55-64. 2003..These results suggest that intolerance of uncertainty plays a key role in our understanding of adolescent worry...
Partners in adversity. IV. Coping and moodP G Surtees
MRC Biostatistics Unit, University Forvie Site, Cambridge, UK
Eur Arch Psychiatry Clin Neurosci 243:319-27. 1994..Details are provided of the construction of a summary measure of coping response based upon the above domains and of its relationship with follow-up mood state after allowance for mood levels at initial interview...
Body checking in the eating disorders: association with narcissistic characteristicsGlenn Waller
Eating Disorders Section, Institute of Psychiatry, King s College London, United Kingdom
Eat Behav 9:163-9. 2008..These patterns are compatible with a model where body checking serves the defensive function of maintaining self-esteem, rather than promoting positive levels of narcissistic self-esteem...
[Hysterical symptoms and the body in old age]J Kipp
Ludwig-Noll-Krankenhaus, , Klinikum Kassel, , 34134 Kassel
Z Psychosom Med Psychother 47:167-78. 2001..Since the conversion requires the body scheme to portray psychic conflicts the somatogenic organization function (Heuft) is repealed and as a result the aging processes of the body and therefore aging are not dealt with adequately...
Validation of the Comprehensive Assessment of Defense Style (CADS): mothers' and children's responses to the stresses of missile attacksL Wolmer
Tel Aviv-Brull Community Mental Health Center, Israel
J Nerv Ment Dis 189:369-76. 2001..The CADS factors correlated with the defenses of the Defense Mechanisms Manual...
Negative appraisals and cognitive avoidance of intrusive memories in depression: a replication and extensionAlishia D Williams
School of Psychology, The University of New South Wales, New South Wales, Sydney, NSW 2052, Australia
Depress Anxiety 25:E26-33. 2008..The results support the validity of borrowing from PTSD models to elucidate the cognitive mechanisms that maintain intrusive memories in depressed samples...
Testing the stress-buffering effects of self engagement among soldiers on a military operationThomas W Britt
Walter Reed Army Institute of Research, USA
J Pers 71:245-65. 2003..The results are discussed in terms of the potential mechanisms by which self engagement might protect individuals from stressful circumstances...
Why do anal wounds heal adequately? A study of the local immunoinflammatory defense mechanismsPedro Roberto de Paula
Departamento de Medicina, Universidade de Taubate, Taubate, Brazil
Dis Colon Rectum 47:1861-7. 2004..The aim of this study was to identify the tissue defense immunoinflammatory mechanisms present in the healing process of anal region wounds resulting from hemorrhoidectomy by the open technique...
Candidate's thesis: enhancing intrinsic cochlear stress defenses to reduce noise-induced hearing lossRichard D Kopke
Department of Defence Spatial Orientation Center, Naval Medical Center San Diego, California 92134, USA
Laryngoscope 112:1515-32. 2002..We present the results of three different approaches to enhance intrinsic cochlear defense mechanisms against oxidative stress...
Serine proteinase inhibitors in the Compositae: distribution, polymorphism and propertiesAlexander V Konarev
All Russian Institute of Plant Protection VIZR, Podbelsky 3, St Petersburg, 189620 Russia
Phytochemistry 59:279-91. 2002..subtilisin and trypsin and/or chymotrypsin (T/C/SI) had the widest distribution and may be involved in plant defense mechanisms. They were found in many species of the subfamilies Carduoideae (genera Carthamus, Centaurea, Cirsium), ..
Role of circadian rhythm and endogenous melatonin in pathogenesis of acute gastric bleeding erosions induced by stressT Brzozowski
Department of Physiology, Jagiellonian University Medical College, 16 Grzegorzecka Street, Cracow, Poland
J Physiol Pharmacol 58:53-64. 2007..in response to the imbalance between the aggressive factors promoting mucosal damage and the gastric mucosal defense mechanisms including predominantly gastric blood flow (GBF), biosynthesis of gastroprotective prostaglandins (PG) and ..
[Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients]Agnieszka K Kurnatowska
Zakład Leczenia Chorób Pasozytniczych i Grzybic, Katedra Biologii i Parazytologii Lekarskiej, Uniwersytet Medyczny, Pl Gen J Hallera 1, 90 647 Łódź
Wiad Parazytol 55:415-23. 2009..different genera and species can cause organ-limited or systemic infections after disrupting of the natural defense mechanisms in a human organism. The treatment of mycoses still encounters considerable difficulties...
[Granulomatous diseases and pathogenic microorganism]Yoshikazu Inoue
Clinical Research Center, National Hospital Organization Kinki chuo Chest Medical Center, Osaka, Japan
Kekkaku 83:115-30. 2008..Balance between pathogenic microorganisms and defense mechanisms of the host might be important in the special immunologic reaction...
Commensal bacteria (normal microflora), mucosal immunity and chronic inflammatory and autoimmune diseasesHelena Tlaskalova-Hogenova
Department of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
Immunol Lett 93:97-108. 2004..However, at the same time the mucosal immune system must provide local defense mechanisms against environmental threats (e.g. invading pathogens)...
Role of capsaicin-sensitive nerves and histamine H1, H2, and H3 receptors in the gastroprotective effect of histamine against stress ulcers in ratsArtur Dembinski
Department of Physiology, Jagiellonian University Medical School, 16 Grzegorzecka Street, Krakow 31 531, Poland
Eur J Pharmacol 508:211-21. 2005..However, it has been also demonstrated that gastric defense mechanisms, which prevent mucosal injury, are enhanced by the same factors that increase acid secretion...
Responses of Mycobacterium tuberculosis hemoglobin promoters to in vitro and in vivo growth conditionsSudesh Pawaria
Institute of Microbial Technology, Sector 39 A, Chandigarh 160036, India
Appl Environ Microbiol 74:3512-22. 2008..of Mycobacterium tuberculosis as one of the dreaded human pathogens lies in its ability to utilize different defense mechanisms in response to the varied environmental challenges during the course of its intracellular infection, latency,..
Functional mimics of glutathione peroxidase: bioinspired synthetic antioxidantsKrishna P Bhabak
Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore 560012, India
Acc Chem Res 43:1408-19. 2010..Mammalian cells have elaborate antioxidant defense mechanisms to control the damaging effects of ROS...
Langerhans cells in benign, premalignant and malignant skin lesions of renal transplant recipients and the effect of retinoid therapyG E Gibson
Department of Dermatology, Beaumont Hospital, Dublin, Ireland
J Eur Acad Dermatol Venereol 10:130-6. 1998..cells (LC) are a unique population of antigen-presenting cells in the epidermis which may play a role in the defense mechanisms against skin tumors...
Circadian rhythms, oxidative stress, and antioxidative defense mechanismsRudiger Hardeland
Institute of Zoology and Anthropology, University of Gottingen, Gottingen, Germany
Chronobiol Int 20:921-62. 2003....
[Study of local immunity of lower genital tract infections]Dai Zhang
Department of Obstetrics and Gynecology, Peking University First Hospital, Beifing 100034, China
Zhonghua Fu Chan Ke Za Zhi 44:13-5. 2009To investigate the profile of local immunity of vagina and the immune defense mechanisms against lower genital tract infections.
Mode of action of butoxyethanol-induced mouse liver hemangiosarcomas and hepatocellular carcinomasJ E Klaunig
Indiana School of Medicine, 635 Barnhill Drive, MS 547, Indianapolis, IN 46202, USA
Toxicol Lett 156:107-15. 2005..In contrast, in the mouse, the reactive oxygen species would override antioxidant defense mechanisms and allow the proposed mode of action to move forward...
Oxidative stress caused by acute and chronic exposition to altitudeZeno Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, ARGE Alpine Medicine, Medical University of Graz, Graz, Austria
Wien Med Wochenschr 155:136-42. 2005..Five defense mechanisms are well established for lowlanders who are exposed to acute hypoxic hypoxia...
Genetic risk profiles for cancer susceptibility and therapy responseHelmut Bartsch
Deutsches Krebsforschungszentrum, Toxicology and Cancer Risk Factors, Heidelberg, Germany
Recent Results Cancer Res 174:19-36. 2007..Inherited and acquired deficiencies in host defense mechanisms against DNA damage (metabolic and DNA repair enzymes) can modify cancer susceptibility as well as therapy ..
5-Lipoxygenase reaction products modulate alveolar macrophage phagocytosis of Klebsiella pneumoniaeP Mancuso
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0642, USA
Infect Immun 66:5140-6. 1998..on neutrophil chemotaxis and activation have been established, their role in modulating innate host defense mechanisms is poorly understood. In a previous study (M. Bailie, T. Standiford, L. Laichalk, M. Coffey, R...
Mixed infections with Porphyromonas gingivalis and Treponema denticola cause excessive inflammatory responses in a mouse pneumonia model compared with monoinfectionsRyuta Kimizuka
Department of Microbiology, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba City, Chiba 261 8502, Japan
Microbes Infect 5:1357-62. 2003..However, defense mechanisms and responses to these bacterial infections in the lung in vivo remain poorly understood...
Rickettsia rickettsii infection of cultured human endothelial cells induces heme oxygenase 1 expressionElena Rydkina
Hematology Oncology Unit, Vascular Medicine Progam, Department of Medicine, University of Rochester School of Medicine and Dentistry, New York 14642, USA
Infect Immun 70:4045-52. 2002Existing evidence suggests that oxidative insults and antioxidant defense mechanisms play a critical role in the host cell response during infection of endothelial cells by Rickettsia rickettsii, the causative agent of Rocky Mountain ..
Expression of self-complementary hairpin RNA under the control of the rolC promoter confers systemic disease resistance to plum pox virus without preventing local infectionTiziana Pandolfini
Dipartimento Scientifico Tecnologico, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy
BMC Biotechnol 3:7. 2003..gene silencing (PTGS), is involved in several biological phenomena, including adaptative defense mechanisms against plant viruses...
Core temperature cooling in healthy volunteers after rapid intravenous infusion of cold and room temperature saline solutionTracy M Moore
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Ann Emerg Med 51:153-9. 2008..of cold normal saline solution is a simple and inexpensive method for initiating hypothermia, human cold-defense mechanisms potentially make this route stressful or ineffective...
Research Grants
- IRON ACQUISITION IN BORDETELLA PERTUSSISSANDRA KAY ARMSTRONG; Fiscal Year: 2010..Iron that is essential for virtually all bacterial growth is actively withheld by mammalian defense mechanisms. Bordetella pertussis and Bordetella bronchiseptica are highly genetically related bacterial species that ..
- Host Defense Mechanisms in Chronic Lung DiseaseJo Rae Wright; Fiscal Year: 2007..This project investigates the role of TLRs in chronic lung disease in conjunction with Projects 2, 3 and 4. In addition, patient samples from Project 2 will be analyzed. The project will interact with all the Cores. (End of Abstract) ..
- MANIPULATION OF PHAGOCYTOSIS IN MACROPHAGESJoel Swanson; Fiscal Year: 2003..leads to their degradation, some pathogenic microorganisms survive phagocytosis and evade macrophage defense mechanisms. Listeria monocytogenes is an intracellular pathogen that survives by passing from phagosomes into cytoplasm...
- ORAL EPITHELIAL CELL CYTOKINES CANDIDA & PMN ACTIVATIONAnna Dongari Bagtzoglou; Fiscal Year: 2002..define host cellular responses during the invasion process and enhance those responses that are relevant to defense mechanisms. Compelling experimental evidence suggests that the primary effector cell responsible for Candida clearance ..
- Regulatory Oxygenases in Vasculopathic RickettsiosesSANJEEV SAHNI; Fiscal Year: 2007..in the abilities of SF and typhus group (TG) organisms to trigger ROS generation and activate anti-oxidant defense mechanisms, likely due to distinct differences in their intracytoplasmic behavior...
- CYTOKINE INFLAMMATORY MEDIATORS AND MUCIN REGULATION IN MIDDLE EAR EPITHELIUMJoseph E Kerschner; Fiscal Year: 2010..media is a cytokine dependent process and that mucins are associated with chronic ear disease, middle ear defense mechanisms and pathogen viability...
- CYTOKINE INFLAMMATORY MEDIATORS AND MUCIN REGULATION IN MIDDLE EAR EPITHELIUMJoseph Kerschner; Fiscal Year: 2007..media is a cytokine dependent process and that mucins are associated with chronic ear disease, middle ear defense mechanisms and pathogen viability...
- RENIN/ANGIOTENSIN SYSTEM AND FIBRINOLYSIS IN HUMANSDouglas Vaughan; Fiscal Year: 2001..on the effects of the RAS on the plasminogen activator system, which serves as one of the major endogenous defense mechanisms against intravascular thrombosis, and plays a critical role in vascular and tissue remodeling as well...
- Neutrophil Accumulation in Bacterial PneumoniaSamithamby Jeyaseelan; Fiscal Year: 2009..Recruitment of neutrophils into the lungs is one of the most important defense mechanisms in the initial host defense against bacterial infection...
- Neutrophil Accumulation in Bacterial PneumoniaSamithamby Jeyaseelan; Fiscal Year: 2009..Recruitment of neutrophils into the lungs is one of the most important defense mechanisms in the initial host defense against bacterial infection...
- Disruption of Innate Immune Function by P.Gingivalis Phosphotidylethanolamine LipToshihisa Kawai; Fiscal Year: 2007In the oral cavity, where multiple bacteria colonize, epithelial cells engage in innate defense mechanisms, which include building a physical barrier against infection and secreting innate immune antimicrobial peptides...
- Neutrophil Accumulation in Bacterial PneumoniaSamithamby Jeyaseelan; Fiscal Year: 2010..Recruitment of neutrophils into the lungs is one of the most important defense mechanisms in the initial host defense against bacterial infection...
- ADENOSINE AND PYRUVATE PROTECTION DURING HEART SURGERYRobert Mentzer; Fiscal Year: 2003..new therapeutic strategies to improve myocardial tolerance to ischemia by targeting the heart's endogenous defense mechanisms against oxidative stress...
- MUCOSAL DEFENSE MECHANISMS IN SUBSTANCE ABUSEDavid Brown; Fiscal Year: 2009....
- MUCOSAL DEFENSE MECHANISMS IN SUBSTANCE ABUSEDavid R Brown; Fiscal Year: 2010....
- Non-CD4 Host defense against P. carinii PneumoniaJay K Kolls; Fiscal Year: 2010..Therefore, we have been seeking to better understand how CD4+ T cell independent (CD4IND) host defense mechanisms might defend against PC...
- Antimicrobial Peptides & Innate Immunity in Otitis MediaLAUREN BAKALETZ; Fiscal Year: 2006Antimicrobial polypeptides (APs) are key components of the primary defense mechanisms of mucus membranes, providing first-line inactivation of bacteria, fungi and viruses on the vast epithelial surfaces that line the respiratory, ..
- CD8 AND GAMMA/DELTA T CELLS IN P CARINII PNEUMONIAJay Kolls; Fiscal Year: 2002..in long term immune reconstitution in patients with AIDS, understanding non-CD4+ T cell dependent host defense mechanisms operative in opportunistic infections may be critical...
- Host-Pathogen Interactions in the Mammalian AirwayGill Diamond; Fiscal Year: 2006..Deficiencies in these defenses may result in recurrent airway infections. One of these defense mechanisms is the inducible production of beta-defensins, a class of homologous antibiotic peptides highly abundant in ..
- Synergy of Host Defense Mechanisms in the LungArturo Casadevall; Fiscal Year: 2009..Furthermore, these studies will provide information that could be used to design vaccines and new therapies based on immunological reagents such as antibodies. ..
- Synergy of Host Defense Mechanisms in the LungArturo Casadevall; Fiscal Year: 2010..Furthermore, these studies will provide information that could be used to design vaccines and new therapies based on immunological reagents such as antibodies. ..
- SYNERGY OF HOST DEFENSE MECHANISMS IN LUNGArturo Casadevall; Fiscal Year: 2006..By comparing the immune response in Ab-permissive and Ab-non-permissive murine strains we will learn the conditions and mechanisms by which Ab-mediates protection against C. neoformans. ..
