feeding behavior

Summary

Summary: Behavioral responses or sequences associated with eating including modes of feeding, rhythmic patterns of eating, and time intervals.

Top Publications

  1. pmc Increased proportions of outdoor feeding among residual malaria vector populations following increased use of insecticide-treated nets in rural Tanzania
    Tanya L Russell
    Ifakara Health Institute, Biomedical and Environmental Thematic Group, Ifakara, Tanzania
    Malar J 10:80. 2011
  2. ncbi Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
    T Sakurai
    Howard Hughes Medical Institute, Department of Molecular Genetics, University of Texas Southwestern Medical Center at Dallas, 75235 9050, USA
    Cell 92:573-85. 1998
  3. ncbi Central nervous system control of food intake and body weight
    G J Morton
    Department of Medicine, Harborview Medical Center and University of Washington, Seattle, Washington 98104, USA
    Nature 443:289-95. 2006
  4. pmc Human exposure to anopheline mosquitoes occurs primarily indoors, even for users of insecticide-treated nets in Luangwa Valley, South-east Zambia
    Aklilu Seyoum
    Liverpool School of Tropical Medicine, Vector Group, Pembroke Place, Liverpool L3 5QA, UK
    Parasit Vectors 5:101. 2012
  5. ncbi A role for ghrelin in the central regulation of feeding
    M Nakazato
    Third Department of Internal Medicine, Miyazaki Medical College, Kiyotake, Japan
    Nature 409:194-8. 2001
  6. ncbi AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
    Yasuhiko Minokoshi
    Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts 02215, USA
    Nature 428:569-74. 2004
  7. ncbi Odor-mediated behavior of Afrotropical malaria mosquitoes
    W Takken
    Laboratory of Entomology, Wageningen Agricultural University, The Netherlands
    Annu Rev Entomol 44:131-57. 1999
  8. pmc Obesity and metabolic syndrome in circadian Clock mutant mice
    Fred W Turek
    Department of Neurology, Northwestern University, Evanston, IL 60208, USA
    Science 308:1043-5. 2005
  9. pmc UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
    Zane B Andrews
    Section of Comparative Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, Howard Hughes Medical Institute, New York, New York 10021, USA
    Nature 454:846-51. 2008
  10. pmc Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
    F Damiola
    , Sciences II, , CH-1211 Geneva, Switzerland
    Genes Dev 14:2950-61. 2000

Detail Information

Publications347 found, 100 shown here

  1. pmc Increased proportions of outdoor feeding among residual malaria vector populations following increased use of insecticide-treated nets in rural Tanzania
    Tanya L Russell
    Ifakara Health Institute, Biomedical and Environmental Thematic Group, Ifakara, Tanzania
    Malar J 10:80. 2011
    ..In the surveyed area of rural southern Tanzania, bed net use steadily increased over the last decade, reducing malaria transmission intensity by 94%...
  2. ncbi Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
    T Sakurai
    Howard Hughes Medical Institute, Department of Molecular Genetics, University of Texas Southwestern Medical Center at Dallas, 75235 9050, USA
    Cell 92:573-85. 1998
    ..prepro-orexin mRNA level is up-regulated upon fasting, suggesting a physiological role for the peptides as mediators in the central feedback mechanism that regulates feeding behavior.
  3. ncbi Central nervous system control of food intake and body weight
    G J Morton
    Department of Medicine, Harborview Medical Center and University of Washington, Seattle, Washington 98104, USA
    Nature 443:289-95. 2006
    ..This new information provides a biological context within which to consider the global obesity epidemic and identifies numerous potential avenues for therapeutic intervention and future research...
  4. pmc Human exposure to anopheline mosquitoes occurs primarily indoors, even for users of insecticide-treated nets in Luangwa Valley, South-east Zambia
    Aklilu Seyoum
    Liverpool School of Tropical Medicine, Vector Group, Pembroke Place, Liverpool L3 5QA, UK
    Parasit Vectors 5:101. 2012
    ..We studied the human biting behaviour of the malaria vector Anopheles funestus Giles and the potential malaria vector Anopheles quadriannulatus Theobald in Luangwa valley, south-east Zambia...
  5. ncbi A role for ghrelin in the central regulation of feeding
    M Nakazato
    Third Department of Internal Medicine, Miyazaki Medical College, Kiyotake, Japan
    Nature 409:194-8. 2001
    ..We conclude that ghrelin is a physiological mediator of feeding, and probably has a function in growth regulation by stimulating feeding and release of growth hormone...
  6. ncbi AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
    Yasuhiko Minokoshi
    Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts 02215, USA
    Nature 428:569-74. 2004
    ..Thus, hypothalamic AMPK plays a critical role in hormonal and nutrient-derived anorexigenic and orexigenic signals and in energy balance...
  7. ncbi Odor-mediated behavior of Afrotropical malaria mosquitoes
    W Takken
    Laboratory of Entomology, Wageningen Agricultural University, The Netherlands
    Annu Rev Entomol 44:131-57. 1999
    ..It is foreseen that increased knowledge of odor-mediated behaviors will be applied in the development of novel sampling techniques and possibly alternative methods of intervention to control malaria...
  8. pmc Obesity and metabolic syndrome in circadian Clock mutant mice
    Fred W Turek
    Department of Neurology, Northwestern University, Evanston, IL 60208, USA
    Science 308:1043-5. 2005
    ..These results suggest that the circadian clock gene network plays an important role in mammalian energy balance...
  9. pmc UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
    Zane B Andrews
    Section of Comparative Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, Howard Hughes Medical Institute, New York, New York 10021, USA
    Nature 454:846-51. 2008
    ..These results reveal a signalling modality connecting mitochondria-mediated effects of G-protein-coupled receptors on neuronal function and associated behaviour...
  10. pmc Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
    F Damiola
    , Sciences II, , CH-1211 Geneva, Switzerland
    Genes Dev 14:2950-61. 2000
    ..Food-induced phase resetting proceeds faster in liver than in kidney, heart, or pancreas, but after 1 wk of daytime feeding, the phases of circadian gene expression are similar in all examined peripheral tissues...
  11. pmc Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats
    Paul M Johnson
    Laboratory of Behavioral and Molecular Neuroscience, Department of Molecular Therapeutics, The Scripps Research Institute Scripps Florida, Jupiter, Florida, USA
    Nat Neurosci 13:635-41. 2010
    ..Accordingly, we detected compulsive-like feeding behavior in obese but not lean rats, measured as palatable food consumption that was resistant to disruption by an ..
  12. pmc Outdoor host seeking behaviour of Anopheles gambiae mosquitoes following initiation of malaria vector control on Bioko Island, Equatorial Guinea
    Michael R Reddy
    Department of Epidemiology and Public Health, Yale University, New Haven, CT, USA
    Malar J 10:184. 2011
    ..gambiae sensu stricto (s.s.) is the primary malaria vector. The goal of the paper is to evaluate the importance of An gambiae s.l. outdoor host seeking behaviour and discuss its implications for anti-vector interventions...
  13. pmc A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila
    Laura Palanker Musselman
    Division of Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Dis Model Mech 4:842-9. 2011
    ..These data establish a novel Drosophila model of diet-induced insulin resistance that bears strong similarity to the pathophysiology of T2D in humans...
  14. pmc From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior
    Kevin W Williams
    Department of Internal Medicine, Division of Hypothalamic Research, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
    Nat Neurosci 15:1350-5. 2012
    ..This Review highlights contributions to our understanding of peripheral and central factors regulating food intake and energy expenditure...
  15. pmc Impact of promoting longer-lasting insecticide treatment of bed nets upon malaria transmission in a rural Tanzanian setting with pre-existing high coverage of untreated nets
    Tanya L Russell
    Biomedical and Environmental Thematic Group, Ifakara Health Institute, P O Box 53, Ifakara, Tanzania
    Malar J 9:187. 2010
    ..Since 2006, a national-scale programme has promoted the use of longer-lasting insecticide treatment kits (consisting of an insecticide plus binder) co-packaged with all bed nets manufactured in the country...
  16. ncbi Changes in Anopheles funestus biting behavior following universal coverage of long-lasting insecticidal nets in Benin
    Nicolas Moiroux
    MIVEGEC IRD 224 CNRS 5290 UM1 UM2, Institut de Recherche pour le Developpement, Montpellier, France
    J Infect Dis 206:1622-9. 2012
    ..We investigated whether full coverage of long-lasting insecticide-treated mosquito nets (LLINs) may induce a switch in biting behavior in Anopheles funestus, a major malaria vector in Africa...
  17. pmc The role of saliva in tick feeding
    Ivo M B Francischetti
    Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda MD, USA
    Front Biosci (Landmark Ed) 14:2051-88. 2009
    ..This supplemental file is accessble fromhttp://exon.niaid.nih.gov/transcriptome/tick_review/Sup-Table-1.xls.gz...
  18. pmc Neural correlates of food addiction
    Ashley N Gearhardt
    Yale University, 2 Hillhouse Ave, New Haven, CT 06511, USA
    Arch Gen Psychiatry 68:808-16. 2011
    ..Although parallels in neural functioning between obesity and substance dependence have been found, to our knowledge, no studies have examined the neural correlates of addictive-like eating behavior...
  19. ncbi Trophic action of leptin on hypothalamic neurons that regulate feeding
    Sebastien G Bouret
    Division of Neuroscience, Oregon National Primate Research Center and Oregon Health and Science University, Beaverton, OR 97006, USA
    Science 304:108-10. 2004
    ..These results suggest that leptin plays a neurotrophic role during the development of the hypothalamus and that this activity is restricted to a neonatal critical period that precedes leptin's acute regulation of food intake in adults...
  20. ncbi Host selection by Culex pipiens mosquitoes and West Nile virus amplification
    Gabriel L Hamer
    Department of Fisheries and Wildlife, Michigan State University, East Lansing, Michigan 48910, USA
    Am J Trop Med Hyg 80:268-78. 2009
    ..pipiens became infected from feeding on just a few species of birds, including American robins (35%), blue jays (17%, Cyanocitta cristata), and house finches (15%, Carpodacus mexicanus)...
  21. pmc Inferences of diplodocoid (Sauropoda: Dinosauria) feeding behavior from snout shape and microwear analyses
    John A Whitlock
    Museum of Paleontology, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 6:e18304. 2011
    ..Additionally, fortuitous preservation of a large proportion of cranial elements makes them an ideal clade in which to examine feeding behavior.
  22. pmc Silverleaf whitefly induces salicylic acid defenses and suppresses effectual jasmonic acid defenses
    Sonia I Zarate
    Department of Botany and Plant Sciences, Center for Plant Cell Biology, University of California, Riverside, California 92521 0124, USA
    Plant Physiol 143:866-75. 2007
    ..Collectively, these results showed that SLWF-repressed, JA-regulated defenses were associated with basal defense to the SLWF...
  23. ncbi Revisiting Lévy flight search patterns of wandering albatrosses, bumblebees and deer
    Andrew M Edwards
    British Antarctic Survey, High Cross, Madingley Road, Cambridge CB3 0ET, UK
    Nature 449:1044-8. 2007
    ..Our results question the strength of the empirical evidence for biological Lévy flights...
  24. ncbi The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain
    Robert Fredriksson
    Department of Neuroscience, Functional Pharmacology, Uppsala University, Biomedical Center, Uppsala, Sweden
    Endocrinology 149:2062-71. 2008
    ..These results are consistent with the hypothesis that FTO could participate in the central control of energy homeostasis...
  25. ncbi Effective leadership and decision-making in animal groups on the move
    Iain D Couzin
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA
    Nature 433:513-6. 2005
    ..Our model provides new insights into the mechanisms of effective leadership and decision-making in biological systems...
  26. ncbi Confirmatory factor analysis of the Child Feeding Questionnaire: a measure of parental attitudes, beliefs and practices about child feeding and obesity proneness
    L L Birch
    Department of Human Development and Family Studies and Graduate Program in Nutrition, The Pennsylvania State University, University Park, PA 16802, USA
    Appetite 36:201-10. 2001
    ..The CFQ is designed for use with parents of children ranging in age from about 2 to 11 years of age...
  27. pmc Odorant-binding proteins OBP57d and OBP57e affect taste perception and host-plant preference in Drosophila sechellia
    Takashi Matsuo
    Department of Biological Sciences, Tokyo Metropolitan University, Hachioji, Tokyo, Japan
    PLoS Biol 5:e118. 2007
    ..citrifolia. Our finding of the genes involved in host-plant determination may lead to further understanding of mechanisms underlying taste perception, evolution of plant-herbivore interactions, and speciation...
  28. pmc Rapid, reversible activation of AgRP neurons drives feeding behavior in mice
    Michael J Krashes
    Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Clin Invest 121:1424-8. 2011
    ..food-seeking behavior, demonstrating that AgRP neurons engage brain sites controlling multiple levels of feeding behavior. Due to its ease of use and suitability for both acute and chronic regulation, DREADD technology is ideally ..
  29. ncbi NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates
    Serge Luquet
    Howard Hughes Medical Institute and Department of Biochemistry, University of Washington, Box 357370, Seattle, WA 98195, USA
    Science 310:683-5. 2005
    ..that express neuropeptide Y (NPY) and agouti-related protein (AgRP) are thought to be critical regulators of feeding behavior and body weight...
  30. ncbi High-fat diet disrupts behavioral and molecular circadian rhythms in mice
    Akira Kohsaka
    Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208, USA
    Cell Metab 6:414-21. 2007
    ..These results indicate that consumption of a high-calorie diet alters the function of the mammalian circadian clock...
  31. ncbi High-fat diet-induced obesity in animal models
    Niloofar Hariri
    School of Dietetics and Human Nutrition, McGill University, Quebec, Canada
    Nutr Res Rev 23:270-99. 2010
    ..Other factors that affect dietary obesity including feeding rhythmicity, social factors and stress are highlighted. Finally, we comment on the reversibility of high-fat diet-induced obesity...
  32. ncbi Drosophila short neuropeptide F regulates food intake and body size
    Kyu Sun Lee
    Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology, 52 Eoun dong, Yusong gu, Daejeon, 395 333, Korea
    J Biol Chem 279:50781-9. 2004
    ..Also, sNPF overexpression in nervous systems produced bigger and heavier flies. These findings indicate that the sNPF is expressed in the nervous systems to control food intake and regulate body size in Drosophila melanogaster...
  33. pmc The genetics of feeding in Caenorhabditis elegans
    L Avery
    Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas 75235 9038
    Genetics 133:897-917. 1993
    ..or function of the excitable cells of the pharynx, I screened for worms with visible defects in pharyngeal feeding behavior. Fifty-two mutations identified 35 genes, at least 22 previously unknown...
  34. ncbi Caterpillar-induced nocturnal plant volatiles repel conspecific females
    C M De Moraes
    USDA-ARS, CMAVE, PO Box 14565, Gainesville, Florida 32604, USA
    Nature 410:577-80. 2001
    ....
  35. pmc Avoiding effective defenses: strategies employed by phloem-feeding insects
    Linda L Walling
    Department of Botany and Plant Sciences, Center for Plant Cell Biology, University of California, Riverside, CA 92521 0124, USA
    Plant Physiol 146:859-66. 2008
  36. pmc Prandiology of Drosophila and the CAFE assay
    William W Ja
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 104:8253-6. 2007
    Studies of feeding behavior in genetically tractable invertebrate model systems have been limited by the lack of proper methodology...
  37. ncbi Associations between maternal feeding style and food intake of children with a higher risk for overweight
    Katja Kröller
    University of Potsdam, Institute of Psychology, Karl Liebknecht Str 24 25, 14476 Potsdam OT Golm, Germany
    Appetite 51:166-72. 2008
    ..The aim of this study is to examine the impact of different feeding strategies on the child's food intake as well as the effect and influence socio-economic status and weight have on the use of feeding strategies...
  38. ncbi Optimizing the success of random searches
    G M Viswanathan
    Center for Polymer Studies and Department of Physics, Boston University, Massachusetts 02215, USA
    Nature 401:911-4. 1999
    ..We test the theory by analysing experimental foraging data on selected insect, mammal and bird species, and find that they are consistent with the predicted inverse square power-law distributions...
  39. ncbi Gut hormone PYY(3-36) physiologically inhibits food intake
    Rachel L Batterham
    Imperial College Faculty of Medicine at Hammersmith Campus, Du Cane Road, London W12 0NN, UK
    Nature 418:650-4. 2002
    ..Thus, postprandial elevation of PYY(3-36) may act through the arcuate nucleus Y2R to inhibit feeding in a gut-hypothalamic pathway...
  40. ncbi Rapid rewiring of arcuate nucleus feeding circuits by leptin
    Shirly Pinto
    Laboratory of Molecular Genetics, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Science 304:110-5. 2004
    ..These data suggest that leptin-mediated plasticity in the ob/ob hypothalamus may underlie some of the hormone's behavioral effects...
  41. ncbi How do plants "notice" attack by herbivorous arthropods?
    Monika Hilker
    Freie Universitat Berlin, Institute of Biology, Berlin, Germany
    Biol Rev Camb Philos Soc 85:267-80. 2010
    ..Understanding the mechanisms of plant responses to the different phases of herbivore attack will be a key challenge in unravelling the complex communication pathways between plants and herbivores...
  42. pmc The availability of potential hosts as a determinant of feeding behaviours and malaria transmission by African mosquito populations
    G F Killeen
    Department of Tropical Medicine, School of Public Health and Tropical Medicine, Center for Infectious Diseases, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA 70112, USA
    Trans R Soc Trop Med Hyg 95:469-76. 2001
    ..Mathematical models based on this definition also represent promising tools for quantifying the dependence of vector longevity, feeding cycle length and dispersal upon host availability...
  43. ncbi Gene expression and glucosinolate accumulation in Arabidopsis thaliana in response to generalist and specialist herbivores of different feeding guilds and the role of defense signaling pathways
    Inga Mewis
    Pennsylvania State University, Department of Entomology, Chemical Ecology Laboratory, State College, PA 16802, USA
    Phytochemistry 67:2450-62. 2006
    ..Both glucosinolate content and gene expression data indicate that salicylate and ethylene signaling repress some jasmonate-mediated responses to herbivory...
  44. pmc Insecticide-treated nets can reduce malaria transmission by mosquitoes which feed outdoors
    Nicodem J Govella
    Ifakara Health Institute, Dar es Salaam, Tanzania
    Am J Trop Med Hyg 82:415-9. 2010
    ..We also review recent reports from Tanzania to show that conventional mosquito behavior measures can underestimate the potential of ITNs because they ignore the importance of human movements...
  45. pmc Dietary composition specifies consumption, obesity, and lifespan in Drosophila melanogaster
    Danielle A Skorupa
    Huffington Center on Aging, and Interdepartmental Program in Cell and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Aging Cell 7:478-90. 2008
    ....
  46. pmc Circadian clocks for all meal-times: anticipation of 2 daily meals in rats
    Ralph E Mistlberger
    Department of Psychology, Simon Fraser University, Burnaby, Canada
    PLoS ONE 7:e31772. 2012
    ..The results favor a multiple oscillator basis for 2-meal anticipatory rhythms and provide no evidence for involvement of cue-dependent interval timing...
  47. pmc Dieting and unhealthy weight control behaviors during adolescence: associations with 10-year changes in body mass index
    Dianne Neumark-Sztainer
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55454, USA
    J Adolesc Health 50:80-6. 2012
    ..Dieting and unhealthy weight control behaviors are common among adolescents and questions exist regarding their long-term effect on weight status...
  48. ncbi Obesity and the environment: where do we go from here?
    James O Hill
    Center for Human Nutrition, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Science 299:853-5. 2003
    ..Having a specific behavioral target for the prevention of weight gain may be key to arresting the obesity epidemic...
  49. ncbi Scaling laws of marine predator search behaviour
    David W Sims
    Marine Biological Association of the United Kingdom, The Laboratory, Citadel Hill, Plymouth PL1 2PB, UK
    Nature 451:1098-102. 2008
    ..This may explain why Lévy-like behaviour seems to be widespread among diverse organisms, from microbes to humans, as a 'rule' that evolved in response to patchy resource distributions...
  50. ncbi Blood-feeding behaviour of the malarial mosquito Anopheles arabiensis: implications for vector control
    I Tirados
    FARM Africa, London, U K
    Med Vet Entomol 20:425-37. 2006
    ..Hence, classical zooprophylaxis is unlikely to have a significant impact on the malaria vectorial capacity of An. arabiensis in Konso, whereas treating cattle with insecticide might do...
  51. ncbi Aphid protein effectors promote aphid colonization in a plant species-specific manner
    Marco Pitino
    The John Innes Centre, Norwich Research Park, Norwich, UK
    Mol Plant Microbe Interact 26:130-9. 2013
    ..persicae colonization on Arabidopsis. Taken together, these results provide evidence that aphid effectors are under positive selection to promote aphid colonization on specific plant species...
  52. pmc Hemolymph sugar homeostasis and starvation-induced hyperactivity affected by genetic manipulations of the adipokinetic hormone-encoding gene in Drosophila melanogaster
    Gyunghee Lee
    Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee 37996, USA
    Genetics 167:311-23. 2004
    ..From these findings, we propose another role for AKH in the regulation of starvation-induced foraging behavior...
  53. pmc Feeding patterns of potential West Nile virus vectors in south-west Spain
    Joaquín Muñoz
    Estacion Biologica de Donana CSIC, Seville, Spain
    PLoS ONE 7:e39549. 2012
    ..Feeding behaviour also interacts with other biotic and abiotic factors that affect virus amplification and transmission...
  54. pmc Biologically meaningful coverage indicators for eliminating malaria transmission
    Samson S Kiware
    Biomedical and Environmental Thematic Group, Ifakara Health Institute, PO Box 53, Ifakara, Tanzania
    Biol Lett 8:874-7. 2012
    ....
  55. ncbi Early biting rhythm in the Afro-tropical vector of malaria, Anopheles arabiensis, and challenges for its control in Ethiopia
    M Yohannes
    Department of Microbiology, Immunology and Parasitology, College of Health Science, Mekelle University, Tigray, Ethiopia
    Med Vet Entomol 26:103-5. 2012
    ..00 hours in the three villages; over 70% of biting activity occurred before 22.00 hours, when people typically retire to bed. This early biting activity may have a negative impact on the efficiency of bednets to control malaria...
  56. pmc Regulation of feeding and metabolism by neuronal and peripheral clocks in Drosophila
    Kanyan Xu
    Howard Hughes Medical Institute, Department of Neuroscience, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Cell Metab 8:289-300. 2008
    Studies in mammals have indicated a connection between circadian clocks and feeding behavior, but the nature of the interaction and its relationship to nutrient metabolism are not understood...
  57. ncbi Lévy walks evolve through interaction between movement and environmental complexity
    Monique de Jager
    Spatial Ecology Department, Netherlands Institute of Ecology NIOO KNAW, Yerseke, Netherlands
    Science 332:1551-3. 2011
    ..Our results emphasize that an interaction between individual selection and habitat complexity shapes animal movement in natural systems...
  58. pmc Quantification of food intake in Drosophila
    Richard Wong
    Institute of Healthy Ageing, and GEE, University College London, London, UK
    PLoS ONE 4:e6063. 2009
    ..This approach provides a practical and reliable method for quantification of food intake in Drosophila under normal, undisturbed culture conditions...
  59. ncbi Neural mechanisms associated with food motivation in obese and healthy weight adults
    Laura E Martin
    Hoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, Kansas, USA
    Obesity (Silver Spring) 18:254-60. 2010
    ....
  60. ncbi Environmental factors that increase the food intake and consumption volume of unknowing consumers
    Brian Wansink
    Department of Marketing and Nutritional Science, University of Illinois at Urbana Champaign, Champaign, Illinois 61820, USA
    Annu Rev Nutr 24:455-79. 2004
    ..For health professionals, this review underscores how small structural changes in personal environments can reduce the unknowing overconsumption of food...
  61. ncbi Public information: from nosy neighbors to cultural evolution
    Etienne Danchin
    U P M C CNRS UMR7625, Bât A 7e étage Case 237, 7 quai Saint Bernard, 75252 Paris Cedex 05, France
    Science 305:487-91. 2004
    ..The use of public information is taxonomically widespread and can enhance fitness. Public information can lead to cultural evolution, which we suggest may then affect biological evolution...
  62. ncbi Mediators of weight loss and weight loss maintenance in middle-aged women
    Pedro J Teixeira
    Department of Exercise and Health, Faculty of Human Kinetics, Technical University of Lisbon, Lisbon, Portugal
    Obesity (Silver Spring) 18:725-35. 2010
    ..For long-term success, interventions must also be effective in promoting exercise intrinsic motivation and self-efficacy...
  63. pmc Allocrine modulation of feeding behavior by the Sex Peptide of Drosophila
    Gil B Carvalho
    Division of Biology 156 29 and 216 76, California Institute of Technology, Pasadena, 91125, USA
    Curr Biol 16:692-6. 2006
    ..Ectopic expression of SP in virgin females mimics the effect of mating on feeding behavior, demonstrating that SP is the main agent controlling this behavioral paradigm...
  64. ncbi Individual feeding specialisation in shorebirds: population consequences and conservation implications
    S E dit Durell
    Centre for Ecology and Hydrology, Dorset, UK
    Biol Rev Camb Philos Soc 75:503-18. 2000
    ....
  65. ncbi Ecological and evolutionary determinants of host species choice in mosquito vectors
    Issa N Lyimo
    Public Health Entomology Unit, Ifakara Health Institute, Off Mlabani Passage, PO Box 53, Ifakara, Tanzania
    Trends Parasitol 25:189-96. 2009
    ....
  66. ncbi Tick ecology: processes and patterns behind the epidemiological risk posed by ixodid ticks as vectors
    S E Randolph
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Parasitology 129:S37-65. 2004
    ..Temperate and tropical patterns will be illustrated with reference mostly to Ixodes ricinus and Rhipicephalus appendiculatus, respectively...
  67. ncbi Extreme diving of beaked whales
    Peter L Tyack
    Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA
    J Exp Biol 209:4238-53. 2006
    ..If the assumptions of these models are correct for beaked whales, then possible decompression problems are more likely to result from an abnormal behavioural response to sonar...
  68. pmc The lipid messenger OEA links dietary fat intake to satiety
    Gary J Schwartz
    Diabetes Research Center, Departments of Medicine and Neuroscience, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY, USA
    Cell Metab 8:281-8. 2008
    ..The results suggest that activation of small-intestinal OEA mobilization, enabled by CD36-mediated uptake of dietary oleic acid, serves as a molecular sensor linking fat ingestion to satiety...
  69. pmc Major signaling pathways modulate Arabidopsis glucosinolate accumulation and response to both phloem-feeding and chewing insects
    Inga Mewis
    Department of Entomology, Chemical Ecology Laboratory, Pennsylvania State University, State College, Pennsylvania 16802, USA
    Plant Physiol 138:1149-62. 2005
    ..Our results indicate that exogenous signal application and plant consumption measures may not provide useful measures of plant responses to actual insect feeding...
  70. ncbi The ecological causes of individual specialisation
    Márcio S Araújo
    Marine Sciences Program, Department of Biological Sciences, Florida International University, Miami, FL 33181, USA
    Ecol Lett 14:948-58. 2011
    ..We discuss some emerging methodological issues as guidelines for researchers studying individual specialisation, and make specific recommendations regarding avenues for future research...
  71. ncbi The evolutionary ecology of insect resistance to plant chemicals
    Laurence Despres
    Laboratoire d Ecologie Alpine, LECA UMR CNRS 5553, Universite Joseph Fourier, BP 53 38041, Grenoble Cedex 09, France
    Trends Ecol Evol 22:298-307. 2007
    ....
  72. ncbi Taste perception and coding in Drosophila
    Natasha Thorne
    Department of Molecular Genetics and Microbiology, Duke University Medical Center, 252 CARL Building Research Drive, Durham, NC 27710 USA
    Curr Biol 14:1065-79. 2004
    ..In Drosophila, a family of gustatory receptors (GRs) expressed in taste neurons is thought to mediate the recognition of sugars and bitter compounds, thereby controlling feeding behavior.
  73. ncbi Relationship between stress, eating behavior, and obesity
    Susan J Torres
    Centre for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Burwood, Victoria, Australia
    Nutrition 23:887-94. 2007
    ....
  74. ncbi Influence of gene action across different time scales on behavior
    Y Ben-Shahar
    Department of Entomology, Neuroscience Program, University of Illinois at Urbana Champaign, 320 Morrill Hall, 505 South Goodwin Avenue, Urbana, IL 61801, USA
    Science 296:741-4. 2002
    ..Previous research showed that allelic differences in PKG expression result in two Drosophila foraging variants. The same gene can thus exert different types of influence on a behavior...
  75. pmc A simulation model of African Anopheles ecology and population dynamics for the analysis of malaria transmission
    Jean Marc O Depinay
    Fogarty International Center, National Institutes of Health, 16 Center Drive, Bethesda MD 20892, USA
    Malar J 3:29. 2004
    ..However, malaria remains uncontrolled and is increasing in many areas, as are vector and parasite resistance to insecticides and drugs...
  76. pmc AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training
    Yexica Aponte
    Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, Virginia, USA
    Nat Neurosci 14:351-5. 2011
    ..of agouti-related peptide (AGRP) or pro-opiomelanocortin (POMC) positively and negatively influence feeding behavior, respectively, possibly by reciprocally regulating downstream melanocortin receptors...
  77. pmc Feeding and reward: perspectives from three rat models of binge eating
    Rebecca L Corwin
    Nutritional Sciences Dept, College of Health and Human Development, The Pennsylvania State University, University Park, PA 16802, United States
    Physiol Behav 104:87-97. 2011
    ..However, overeating, or non-homeostatic feeding behavior, can occur independent of obesity...
  78. ncbi A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding
    Raquel Gomez
    University Institute of Drug Dependencies, Department of Psychobiology, University Complutense of Madrid, Madrid 28223, Spain
    J Neurosci 22:9612-7. 2002
    ..Pretreatment with SR141716A enhanced the inhibition of feeding induced by intraperitoneal administration of oleoylethanolamide. The results reveal an unexpected role for peripheral CB1 receptors in the regulation of feeding...
  79. pmc Evaluation of PermaNet 3.0 a deltamethrin-PBO combination net against Anopheles gambiae and pyrethroid resistant Culex quinquefasciatus mosquitoes: an experimental hut trial in Tanzania
    Patrick Tungu
    Amani Medical Research Centre, National Institute for Medical Research, Muheza, Tanzania
    Malar J 9:21. 2010
    ..PBO is an inhibitor of mixed function oxidases implicated in pyrethroid resistance...
  80. ncbi Microarray-based survey of a subset of putative olfactory genes in the mosquito Anopheles gambiae
    H Biessmann
    Developmental Biology Center, University of California, Irvine, CA 92697, USA
    Insect Mol Biol 14:575-89. 2005
    ....
  81. ncbi Blood-feeding behavior of Aedes albopictus, a vector of Chikungunya on La Réunion
    Helene Delatte
    Research Unit 016, Institut de recherche pour le developpement IRD, Saint Pierre, France
    Vector Borne Zoonotic Dis 10:249-58. 2010
    ..Ae. albopictus showed an opportunistic feeding behavior on a wide range of hosts (from cold-blooded to warm-blooded animals), supporting that it can be implicated in ..
  82. pmc Light at night increases body mass by shifting the time of food intake
    Laura K Fonken
    Department of Neuroscience, Ohio State University, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 107:18664-9. 2010
    ..These data are relevant to the coincidence between increasing use of light at night and obesity in humans...
  83. ncbi Hypothalamic CART is a new anorectic peptide regulated by leptin
    P Kristensen
    Health Care Discovery, Novo Nordisk, Bagsvaerd, Denmark
    Nature 393:72-6. 1998
    ..An antiserum against CART increases feeding in normal rats, indicating that CART may be an endogenous inhibitor of food intake in normal animals...
  84. pmc Changes in vector species composition and current vector biology and behaviour will favour malaria elimination in Santa Isabel Province, Solomon Islands
    Hugo Bugoro
    Australian Army Malaria Institute, Gallipoli Barracks, Enoggera, Australia
    Malar J 10:287. 2011
    ....
  85. ncbi Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin
    Miguel Lopez
    Department of Physiology, School of Medicine, University of Santiago de Compostela, S Francisco s n, 15782 Santiago de Compostela A Coruña, Spain
    Cell Metab 7:389-99. 2008
    ..Overall, our results indicate that modulation of hypothalamic fatty acid metabolism specifically in the VMH in response to ghrelin is a physiological mechanism that controls feeding...
  86. ncbi Whitefly resistance traits derived from the wild tomato Solanum pimpinellifolium affect the preference and feeding behavior of Bemisia tabaci and reduce the spread of Tomato yellow leaf curl virus
    M J Rodríguez-López
    Consejo Superior de Investigaciones Cientificas, Malaga, Spain
    Phytopathology 101:1191-201. 2011
    ..Such behavior resulted in a reduced ability to reach the phloem. The superficial type of resistance observed in ABL 14-8 against B. tabaci probing significantly reduced primary and secondary spread of TYLCV...
  87. ncbi Activation of central melanocortin pathways by fenfluramine
    Lora K Heisler
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Science 297:609-11. 2002
    ..These results provide a mechanistic explanation of d-FEN's anorexic actions and indicate that drugs targeting these downstream melanocortin pathways may prove to be effective and more selective anti-obesity treatments...
  88. pmc Dengue virus infection of the Aedes aegypti salivary gland and chemosensory apparatus induces genes that modulate infection and blood-feeding behavior
    Shuzhen Sim
    W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS Pathog 8:e1002631. 2012
    ..mounts responses to suppress DENV which, in turn, modulates the expression of chemosensory-related genes that regulate feeding behavior. These reciprocal interactions may have the potential to affect DENV transmission between humans.
  89. ncbi Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice
    Sebastien G Bouret
    Division of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon 97006, USA
    J Neurosci 24:2797-805. 2004
    ..Taken together, these findings provide new insight into development of hypothalamic circuits and suggest an anatomical basis for the delayed postnatal regulation of food intake and body weight by leptin...
  90. ncbi Role of glucosinolates in insect-plant relationships and multitrophic interactions
    Richard J Hopkins
    Department of Ecology, Swedish University of Agricultural Sciences, Uppsala S 750 07, Sweden
    Annu Rev Entomol 54:57-83. 2009
    ..Plant breeders may use knowledge on glucosinolates to increase insect resistance in Brassica crops. State-of-the-art techniques, such as mutant analysis and metabolomics, are necessary to identify the exact role of glucosinolates...
  91. ncbi The need to feed: homeostatic and hedonic control of eating
    Clifford B Saper
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neuron 36:199-211. 2002
    ..We also examine the mechanisms for taste and reward systems that provide food with its intrinsically reinforcing properties and explore the links between the homeostatic and hedonic systems that ensure intake of adequate nutrition...
  92. ncbi Neuronal activation in the hypothalamus and brainstem during feeding in rats
    Louise E Johnstone
    Centre for Integrative Physiology, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh EH8 9XD, United Kingdom
    Cell Metab 4:313-21. 2006
    ..Thus orexigenic populations are strongly and rapidly activated at the onset of food presentation, followed rapidly by activity in anorexigenic populations when food is ingested...
  93. ncbi Gut vagal afferents are not necessary for the eating-stimulatory effect of intraperitoneally injected ghrelin in the rat
    Myrtha Arnold
    Institute of Animal Sciences, Swiss Federal Institute of Technology Zurich, Schwerzenbach 8603, Switzerland
    J Neurosci 26:11052-60. 2006
    ....
  94. ncbi Agouti-related peptide-expressing neurons are mandatory for feeding
    Eva Gropp
    Institute for Genetics and Center for Molecular Medicine CMMC, Department of Mouse Genetics and Metabolism, University of Cologne, Zülpicher Str 47, 50674 Koln, Germany
    Nat Neurosci 8:1289-91. 2005
    ....
  95. ncbi Peripheral oscillators: the driving force for food-anticipatory activity
    Carolina Escobar
    Departamento de Anatomia, Facultad de Medicina UNAM, Mexico, Mexico
    Eur J Neurosci 30:1665-75. 2009
    ..This complex may constitute the proposed FEO and is distributed in our peripheral organs as well as within the central nervous system...
  96. ncbi Successful city dwellers: a comparative study of the ecological characteristics of urban birds in the Western Palearctic
    Anders Pape Møller
    Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Universite Pierre et Marie Curie, Bat A, 7 quai St Bernard, Case 237, 75252 Paris Cedex 05, France
    Oecologia 159:849-58. 2009
    ..This suggests that a suite of ecological features providing them with general ecological success characterises species of birds that have successfully invaded urban environments...
  97. ncbi The ecological significance of tool use in New Caledonian crows
    Christian Rutz
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Science 329:1523-6. 2010
    ..Our calculations provide estimates of larva-intake rates and show that just a few larvae can satisfy a crow's daily energy requirements, highlighting the substantial rewards available to competent tool users...
  98. ncbi How many animals really do the Lévy walk?
    Simon Benhamou
    Behavioral Ecology Group, Centre d Ecologie Fonctionnelle et Evolutive, Centre National de la Recherche Scientifique, Montpellier, France
    Ecology 88:1962-9. 2007
    ..In any case, emergent movement patterns should not be confused with the processes that gave rise to them...
  99. ncbi Circadian organization is governed by extra-SCN pacemakers
    Pinar Pezuk
    Department of Biology, University of Virginia, Charlottesville, VA, USA
    J Biol Rhythms 25:432-41. 2010
    ..Taken together, these data show that FEO and MASCO are strong circadian pacemakers able to regulate the phases of peripheral oscillators...
  100. ncbi Experimental evidence for density-dependent reproduction in a cooperatively breeding passerine
    Lyanne Brouwer
    Evolutionary Ecology Group, School of Botany and Zoology, Australian National University, Canberra, ACT 0200 Australia
    Ecology 90:729-41. 2009
    ..Islands with the highest insect densities also had the highest bird densities and the largest breeding groups. Consequently, we suggest that the density-dependent effect on reproduction is caused by competition for food...
  101. pmc The role of dopamine in Drosophila larval classical olfactory conditioning
    Mareike Selcho
    Department of Biology, University of Fribourg, Fribourg, Switzerland
    PLoS ONE 4:e5897. 2009
    ..Future studies of the dopaminergic system need to take into account such cellular dissociations in function in order to be meaningful...

Research Grants71

  1. Thyroid Hormone Action
    THOMAS STERLING SCANLAN; Fiscal Year: 2013
    ..Thus it appears that T1AM is an endogenous anorectic agent, with a biological activity on feeding behavior similar to leptin and melanocortins, which are endogenous signaling molecules that act via central pathways ..
  2. Neural Functioning of Feeding Centers in Obese Youth
    ROBERT STANLEY SHERWIN; Fiscal Year: 2013
    ..to glucose on the functional connections between the hypothalamus and other brain regions implicated in feeding behavior and that these differential effects are magnified in obese adolescents...
  3. Circadian Expression of Procolipase in the Liver: A Metabolic Signal
    Mark E Lowe; Fiscal Year: 2010
    ..mice are kept in constant darkness raises the possibility that these proteins contribute to the regulation of feeding behavior and lipid metabolism during environmental stress...
  4. Chemical Biology Studies of 3-Iodothyronamine and Related Thyroid Hormone Metabol
    THOMAS STERLING SCANLAN; Fiscal Year: 2013
    ..We recently demonstrated that chronic administration of low doses of T1AM inhibit feeding behavior in obese mice;i.e. like leptin, T1AM appears to act as an endogenous anorectic agent...
  5. Mechanisms of Diabetic Hyperphagia and Insulin Resistance
    Michael W Schwartz; Fiscal Year: 2012
    ..and help to clarify how dysfunction within these systems contributes to the pathogenesis of disordered feeding behavior and glucose metabolism in obesity and diabetes...
  6. Melanin-Concentrating Hormone: Ancestral Role in Feeding &Sleep Regulation
    Philippe Mourrain; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): In mammals, melanin-concentrating hormone (hMCH) is a key regulator of feeding behavior, energy homeostasis, and sleep...
  7. The Role of Estradiol and Sex in the Effects of Ghrelin on Meal Patterns and Fos-
    PETER BUTERA; Fiscal Year: 2009
    ..suggest that interactions between ghrelin and estradiol may underlie the inhibitory effects of estradiol on feeding behavior and the weight gain caused by ovariectomy and estrogen withdrawal...
  8. Monoamine Contributions to Neurocircuitry in Eating Disorders
    Walter H Kaye; Fiscal Year: 2013
    ..insula and striatal network contributes to the sensory- interoceptive-hedonic-motivational aspects of feeding behavior. Our data suggest the BOLD response of this network to tastes of sucrose is diminished in REC AN and is ..
  9. Appetite-regulating Hormones and Neurocircuitry in Anorexia Nervosa
    ELIZABETH AUSTEN LAWSON; Fiscal Year: 2013
    ..Studies in animals and humans implicate T in feeding behavior. Moreover, pilot data demonstrate hypoactivation by fMRI in brain regions implicated in T deficiency in ..
  10. Neurochemistry/physiology of proopiomelanocortin neurons
    MALCOLM JAMES LOW; Fiscal Year: 2013
    ..that melanocortin signaling coordinately modulates stereotyped motor, reward, and hedonic aspects of feeding behavior;processes which are particularly relevant to human issues surrounding food choice and meal size in the ..
  11. Diet, Insulin, Dopamine, and Reward.
    Margaret E Rice; Fiscal Year: 2013
    ..Previous studies of effects of insulin on feeding behavior and reward have emphasized the anorexigenic effect of insulin in the medial hypothalamus, implying a role in ..
  12. Improving Outcomes for Women with GDM and Their Infants
    Alison M Stuebe; Fiscal Year: 2013
    ..Trends in breastfeeding duration and intensity, maternal infant feeding behavior, and infant growth trajectory (weight-for-length) will also be measured...
  13. Melanocortin-4 Receptor-dependent regulation of energy balance after gastric bypa
    Vincent Aguirre; Fiscal Year: 2013
    ..relays information regarding nutrient intake to the brain and is involved in the responsive modulation of feeding behavior and glucose metabolism...
  14. PPAR delta functions in liver
    Chih Hao Lee; Fiscal Year: 2013
    ..Furthermore, the rhythmicity of hepatic metabolic function is known to couple the feeding behavior to biochemical reactions of substrate usage, suggesting that hepatic de novo lipogenesis also plays an ..
  15. Inflammatory Cytokine regulation of POMC and Orexin neurons in cachexia.
    AARON GROSSBERG; Fiscal Year: 2012
    ..of cachexia will also be utilized, and the effectiveness of orexin replacement in restoring activity and feeding behavior will be evaluated...
  16. Integration of Feeding and Glucose Metabolism by the Circadian Gene Network
    JOSEPH T BASS; Fiscal Year: 2013
    ..hypoinsulinemia;however, to date, our understanding of the tissue-specific roles of clock genes in feeding behavior and integrative physiology remains incomplete...
  17. Mechanisms of glucosensation mediating food choice behavior in Drosophila
    Monica Dus; Fiscal Year: 2013
    ..in part to the rise in the worldwide incidence of obesity and diabetes, the molecular mechanisms regulating feeding behavior have received much attention...
  18. Hypothalamic Deep Brain Stimulation for Morbid Obesity:Development of a Pig Model
    William P Melega; Fiscal Year: 2010
    ..Electrical stimulation of the specific brain regions involved in feeding behavior will result in modulation of food intake and body weight...
  19. Melanin-Concentrating Hormone: Ancestral Role in Feeding & Sleep Regulation
    Philippe Mourrain; Fiscal Year: 2010
    ..role in feeding &sleep regulation In mammals, melanin-concentrating hormone (hMCH) is a key regulator of feeding behavior, energy homeostasis, and sleep...
  20. Regulated Expression of Hypothalamic CPT1 Using Gutless Adenovirus
    Silvana Obici; Fiscal Year: 2010
    ..To test whether the malonyl CoA levels in hypothalamus regulate feeding behavior and metabolism via modulation of fatty acid oxidation, we propose to express in hypothalamus of adult rats a ..
  21. Therapeutic Opportunities of Targeting Tissue Factor Signaling in Obesity
    Fahumiya Samad; Fiscal Year: 2013
    ..The high fat diet (HFD) fed C57BL/6J mouse model of obesity simulates the human condition, including feeding behavior (hyperphagia), weight gain/energy metabolism, and the development of the metabolic syndrome characterized by ..
  22. Endogenous G-Protein Coupled Receptor Antagonists
    Carrie Haskell-Luevano; Fiscal Year: 2012
    ..have seen the characterization of over 30 pathways that have been identified to participate in and regulate feeding behavior and energy homeostasis...
  23. Time-of-Day-Dependent Feeding Influences Myocardial Function
    MARTIN ELLIOT YOUNG; Fiscal Year: 2012
    ..The consequence of overlooking discrepancies between human and laboratory rodent feeding behavior was recently highlighted by our laboratory;mice fed a caloric-dense high fat meal at the end of the active/..
  24. Translational Research on Addiction to Palatable Food
    Nicole M Avena; Fiscal Year: 2013
    ..teaching and research laboratory in which I can continue to conduct research on the neurobiology of aberrant feeding behavior using both preclinical and clinical models...
  25. Dendritic Spines on AgRP Neurons as Communication Hubs Controlling Feeding
    Dong Kong; Fiscal Year: 2013
    ..AgRP neurons are anabolic: optogenetic or pharmaco-genetic stimulation of AgRP neurons drives intense feeding behavior and promotes obesity;disruption of these neurons in adult mice causes severe anorexia...
  26. Drosophila feeding behavior: New tools for the genetic dissection of prandiology
    William W Ja; Fiscal Year: 2012
    ..short- and long-term food consumption in flies and 2) identify and characterize genetic mutants with abnormal feeding behavior. This work will significantly enhance the capabilities of the field and result in expanded use and ..
  27. The role of vagal afferent neurons in regulating feeding behavior
    GUILLAUME FH DE LARTIGUE; Fiscal Year: 2013
    ..alter expression of receptors and neuropeptide transmitters important in sensing and signalling, to modify feeding behavior. In obesity, the sensitivity of key receptors to their ligands are reduced in VAN, resulting in changes in ..
  28. Hormonal Modulation of Aggression in Drosophila
    Edward A Kravitz; Fiscal Year: 2013
    ..in initiating fights, but in bringing fights to higher intensity levels), courtship behavior, balance and feeding behavior in flies...
  29. Hypothalamic Mechanisms in Cachexia
    Daniel L Marks; Fiscal Year: 2013
    ..The central melanocortin system plays a critical role in regulating feeding behavior, linear growth, metabolic rate, and insulin sensitivity...
  30. The Common Marmoset as a Primate Model of Maternal Obesity
    SUZETTE D contact TARDIF; Fiscal Year: 2010
    ..that the DIO propensity group may differ from the diet resistant, lean group in terms of metabolic parameters;and that adult offspring will mirror their dam in terms of body composition, feeding behavior, and glucose metabolism.
  31. Taste and feeding circuits in Drosophila
    MICHAEL DOUGLAS GORDON; Fiscal Year: 2010
    ..Experiments in this proposal will examine the neural substrates of taste perception and feeding behavior in the fruit fly Drosophila melanogaster...
  32. Regulation of Food Intake via the Glucagon-Like Peptide-1 Receptor
    Julio E Ayala; Fiscal Year: 2013
    ..The long-term goal of this application is to elucidate the mechanisms that regulate multiple aspects of feeding behavior. Defining the mechanisms by which the central Glp1r regulates food intake will identify key control points ..
  33. Appetite: Serotonin and corticotropin releasing factor
    SuJean Choi; Fiscal Year: 2012
    ..paraventricular nuclei (PVN) on neuronal corticotropin releasing factor (CRF) mRNA expression and feeding behavior in rats. PVN CRF neurons are important mediators in the control of feeding behavior;e.g...
  34. PERINATAL METABOLIC AND HORMONAL EFFECTS
    Sherin U Devaskar; Fiscal Year: 2010
    ..The results of our proposed investigations will fill vital gaps in our knowledge and provide the molecular and cellular basis for perinatal nutritional perturbations causing permanent changes in feeding behavior/energy expenditure.
  35. Altering Energy Balance by Systemic Delivery of RNAi to the Neuroendocrine Brain
    Sergio R Ojeda; Fiscal Year: 2013
    ..stimulate energy expenditure, neurons containing neuropeptide Y/Agouti-related peptide (NPY/AgRP) stimulate feeding behavior and inhibit energy expenditure...
  36. Circadian Clock of the Paraventricular Nucleus
    Charles J Weitz; Fiscal Year: 2012
    ..play a vital role in central, endocrine, and autonomic physiological processes, particularly those regulating feeding behavior, energy balance, and glucose homeostasis...
  37. Chemosensing in the Gastrointestinal Tract
    Catia Sternini; Fiscal Year: 2010
    ..using c-fos as marker of neuronal activity, and the role of CCK and PYY, peptides that affect GI function and feeding behavior, acting at CCK1 and Y2 receptors on vagal afferents, 1b) the effects of T2R agonists on vagal pathways using ..
  38. Small Molecule Probes to Investigate Structure and Function of Y Receptors
    C David Weaver; Fiscal Year: 2013
    ..NPY, PYY and PP are 36 residue peptide hormones that play critical roles in regulating feeding behavior and energy homeostasis...
  39. Characterization of a mutation that affects feeding and digestion in Drosophila
    EDWARD BLUMENTHAL; Fiscal Year: 2009
    ..research is to understand the genes and physiological pathways required for the regulation of digestion and feeding behavior in the fruit fly Drosophila melanogaster, an organism that has proven to be an excellent model system for ..
  40. Optogenetic Control of Vigilance State Transition
    Luis de Lecea; Fiscal Year: 2013
    ..These experiments may also lead to new and enhanced treatments for narcolepsy, insomnia and other sleep disorders. ..
  41. Glial-Neural Interactions in Autonomic Control
    Richard C Rogers; Fiscal Year: 2012
    ..PAR activation could be due to glial interactions with brainstem neurons that control digestive functions and feeding behavior. Even more important is the possibility that glial-neural communication in the NST has wider significance as ..
  42. Role of SMRT and NCoR in adipocyte differentation and function
    Ronald N Cohen; Fiscal Year: 2012
    ..in the uptake and storage of energy as triglyceride, the adipocyte is a complex endocrine cell that regulates feeding behavior and insulin action...
  43. Hindbrain Actions of Leptin
    Gerlinda E Hermann; Fiscal Year: 2011
    ..It is also a potent inhibitor of feeding behavior. A great deal is known about how leptin can invoke changes in transcription, resulting in the enhancement or ..
  44. Sim1 Function in Feeding Regulation
    Andrew R Zinn; Fiscal Year: 2013
    ..factor? Which PVN neurons are responsible for the hyperphagia of Sim1 mice? If the effects of Sim1 on feeding behavior are due to its actions in adults, genes that are transcriptionally regulated by Sim1 become potential targets ..
  45. Neural Dysfunction of Interoception in Adolescents Diagnosed with Anorexia Nervos
    AMANDA B GRETHE; Fiscal Year: 2010
    Individuals with anorexia nervosa (AN) have aberrant feeding behavior, disturbances of emotionality and impulse control, and have high rates of relapse after weight restoration1, 2. There is no proven treatment that reverses symptoms...
  46. A novel neuropeptide system involved in drug abuse
    Olivier Civelli; Fiscal Year: 2013
    ..of the MCH1R however had led to the conclusion that there was much more to the MCH system than only a role in feeding behavior. Of most interest, we had found that the MCH system is predominantly a CNS system and that the highest level ..
  47. Diet-Induced Plasticity of Proopiomelanocortin Neurons
    AARON JEFFREY MERCER; Fiscal Year: 2012
    ..provided by applicant): Central proopiomelanocortin (POMC) neuron, a circuit that promotes anorectic feeding behavior and negative energy balance, is one of the best-defined neural networks regulating metabolic function...
  48. Correction of obesity by optogenetic manipulation of striatal neurons
    ELIZABETH KATHERINE SCHWARTZ; Fiscal Year: 2013
    ..we hypothesize that optogenetic activation of D1 expressing NAc medium spiny neurons will increase feeding behavior and feeding-induced reward, and will lead to hyperphagia and weight gain...
  49. Circadian rhythms and skeletal muscle
    KARYN ANN ESSER; Fiscal Year: 2012
    ..rhythms have long been known to influence behavioral and biological processes such as physical activity and feeding behavior. The fundamental importance of this system, which works to link physiology with the day/night cycle, is ..
  50. Mechanisms of dietary restriction in Drosophila
    Scott Pletcher; Fiscal Year: 2009
    ..DR response will be examined by elucidating the mechanisms through which the gene ponchik modulates obesity, feeding behavior, and longevity...
  51. Development of neuronal tracers to study leptin modulation of dopamine circuits
    Ralph J DiLeone; Fiscal Year: 2010
    ..the hypothalamus, it is now clear that leptin signals directly to dopamine neurons of the midbrain to reduce feeding behavior and alter responses to drugs of abuse...
  52. Receptor Regulation of CCK Cell Function
    Rodger A Liddle; Fiscal Year: 2013
    ..2. To characterize the role of ILDR in regulating CCK secretion, gallbladder function and feeding behavior in mice in vivo...
  53. Ecological impacts of forest disturbance on La Crosse encephalitis virus dynamics
    MARIA RICHETTA CAMILLE HARRIS; Fiscal Year: 2010
    ..studies: (1) FCD effects on mosquito vector and vertebrate host communities, (2) FCD effects on mosquito host-feeding behavior, (3) LAC vector competence of Cx...
  54. Characterization of Portal Vein Glucose Sensor Responsible for Satiety Control
    Chung Owyang; Fiscal Year: 2013
    ..Understanding the signal transduction cascade utilized by the portal vein glucose sensor to regulate feeding behavior may provide insight as to why impaired glucose signaling occurs in obesity and patients with metabolic ..
  55. Obesity is a Surgical Problem
    Michael W Mulholland; Fiscal Year: 2013
    ..4) To determine the role Asb-4 in feeding behavior. We hypothesize that ankyrin repeat and SOCS box containing protein 4 is a crucial intracellular protein in ..
  56. Cross-talk between the circadian clock and the cAMP signaling pathway
    Satchidananda Panda; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Feeding behavior in mammals is both episodic and circadian. Accordingly, mammals have developed mechanisms to temporally regulate liver gluconeogenesis to maintain glucose homeostasis...
  57. The Role of the Thalamus in Taste Processing
    Kenichi Tokita; Fiscal Year: 2011
    ..To understand how the sense of taste effectively guides feeding behavior, it is necessary to reveal the exact roles of VPMpc in the central gustatory system...
  58. Daily Rhythms and Health: Obesity and Related Disorders
    JULIE SUZANNE PENDERGAST; Fiscal Year: 2013
    ..that consumption of a diet rich in saturated fat (bt not monounsaturated fat) alters daily rhythms of feeding behavior and liver physiology through a toll-like receptor 4-mediated mechanism...
  59. Endosymbiont, Arbovirus &Mosquito Interactions and the Disease Control
    Zhiyong Xi; Fiscal Year: 2013
    ..We will focus on the fitness cost on the mosquito longevity, fecundity, and blood-feeding behavior. We anticipate this knowledge will improve genetic technology and its application in reducing vector capacity ..
  60. The role of mu opoid receptors in diet-induced obesity
    Maria J Barnes; Fiscal Year: 2013
    ..is significantly increased in multiple areas of the central nervous system that are known to be involved in feeding behavior. We hypothesize that the increased mu opioid receptors are contributing to the overeating and increased fat ..
  61. Mechanisms of dietary restriction in Drosophila
    Scott D Pletcher; Fiscal Year: 2013
    ..by elucidating the mechanisms through which a newly described gene that we call ponchik modulates obesity, feeding behavior, and longevity...
  62. AGRP NEURONS. NMDARs, Spines, Source of Excitatory Input and Downstream Effectors
    Bradford B Lowell; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The brain regulates feeding behavior and metabolism however the neurocircuitry responsible for this is largely unknown...
  63. DIOXINS AND HYPOTHALAMIC APPETITE NEUROPEPTIDES
    GEORGE GREELEY; Fiscal Year: 2000
    ..to PolyChlorinated Aromatic Hydrocarbons (PCAHs) or to mixtures of PCAHs disrupts the central control of feeding behavior. PCAHs, such as polychlorinated dibenzo-rho-dioxins (PCDDs), biphenyls (PCBs) and dibenzofurans (PCDFs) ..
  64. SUBCORTICAL MODULATION OF THE DORSAL VAGAL COMPLEX
    Xueguo Zhang; Fiscal Year: 2002
    ..certain forebrain structures, such as the hypothalamus and amygdala, play a particularly important role in feeding behavior. Unfortunately, while it is clear that these forebrain regions are important in the regulation of feeding, we ..
  65. Nucleus Accumbens-Mediated Feeding: Output Pathways
    Thomas R Stratford; Fiscal Year: 2010
    ..project is to identify and characterize the neural circuits through which the AcbSh produces changes in Feeding behavior. Our fundamental working hypothesis is that the AcbSh affects feeding by potently regulating neural activity ..
  66. CORRELATES OF PRETERM AND TERM INFANT FEEDING OUTCOMES
    Karen Pridham; Fiscal Year: 1992
    ..fullterm infants) through the first year post term; and (b) examines the effect of maternal and infant feeding behavior on these outcomes...
  67. Structural Domains Essential for Serotonin Receptor Pharmacology
    Bryan Roth; Fiscal Year: 2006
    ..central nervous system processes including the modulation of mood, perception and anxiety, the regulation of feeding behavior and the control of sleep and wakefulness...
  68. Screening Method for GPCRs Related to Appetite
    MARIA MORANO; Fiscal Year: 2009
    ..This proposal focuses on developing testing platforms for GPCR families associated with feeding behavior. A distinguishing feature of the drug-discovery strategy we are pursuing is that is based on an efficient and ..
  69. Maternal Nutrition Education and Early Childhood Caries: A Randomized Field Trial
    BENJAMIN WILK CHAFFEE; Fiscal Year: 2012
    ..use, plays an import role in the development of dental caries, and thus, efforts to improve nutrition and feeding behavior may yield oral health benefits above and beyond improvements in general health...
  70. SUCROSE AND/OR FAT INGESTION EFFECT ON OPIOIDS
    Allen Levine; Fiscal Year: 2003
    ..sweet and/or fat) results in an increase in the release of endogenous opioids at brain sites involved in feeding behavior and/or "reward...
  71. CANNABINOIDS AND THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS
    Laura Murphy; Fiscal Year: 2002
    ..in the ability of cannabinoids to decrease luteinizing hormone (LH) and induce catalepsy and alterations in feeding behavior will be investigated...