Summary: The total number of individuals inhabiting a particular region or area.

Top Publications

  1. Alt K, Benz M, Muller W, Berner M, Schultz M, Schmidt Schultz T, et al. Earliest evidence for social endogamy in the 9,000-year-old-population of Basta, Jordan. PLoS ONE. 2013;8:e65649 pubmed publisher
    ..Yet, the accompanying archaeological finds document far-reaching economic exchange with neighboring groups and a population density hitherto unparalleled...
  2. Sultan A, Tata L, West J, Fiaschi L, Fleming K, Nelson Piercy C, et al. Risk factors for first venous thromboembolism around pregnancy: a population-based cohort study from the United Kingdom. Blood. 2013;121:3953-61 pubmed publisher
    ..These risk factors should receive careful consideration when assessing the potential need for thromboprophylaxis during the postpartum period. ..
  3. Marostica E, Russu A, Gomeni R, Zamuner S, De Nicolao G. A PCA approach to population analysis: with application to a Phase II depression trial. J Pharmacokinet Pharmacodyn. 2013;40:213-27 pubmed publisher
    ..Furthermore, the proposed method performs well on the experimental data. This approach can be useful whenever a mechanistic modelling procedure cannot be pursued. Moreover, it could support subsequent semi-mechanistic model building. ..
  4. Teshigawara S, Wada J, Hida K, Nakatsuka A, Eguchi J, Murakami K, et al. Serum vaspin concentrations are closely related to insulin resistance, and rs77060950 at SERPINA12 genetically defines distinct group with higher serum levels in Japanese population. J Clin Endocrinol Metab. 2012;97:E1202-7 pubmed publisher
    ..99 ± 0.04 vs. 0.86 ± 0.02 ng/ml; P < 0.01). Both in T2D and genotyped Japanese population, serum vaspin levels closely correlated with homeostasis model of assessment for insulin resistance rather than ..
  5. Rohlfs R, Fullerton S, Weir B. Familial identification: population structure and relationship distinguishability. PLoS Genet. 2012;8:e1002469 pubmed publisher
    ..Using these confidence intervals, we consider familial searching in a structured population. We show that relatives and unrelated individuals from population samples with lower gene diversity over the ..
  6. Mfady D, Sadiq M, Khabour O, Fararjeh A, Abu Awad A, Khader Y. Associations of variants in MTHFR and MTRR genes with male infertility in the Jordanian population. Gene. 2014;536:40-4 pubmed publisher
    ..05). In addition, none of the examined polymorphisms was related to any of the semen parameters in the infertile group. In conclusion, this study showed that MTHFR C677T polymorphism is associated with male infertility in Jordanians. ..
  7. Magnusson K, Østerås N, Mowinckel P, Natvig B, Hagen K. No strong temporal relationship between obesity and multisite pain--results from a population-based 20-year follow-up study. Eur J Pain. 2014;18:120-7 pubmed publisher
    ..the cross-sectional and prospective associations between overweight/obesity and multisite pain in a general population. In a 20-year population-based prospective cohort study, persons aged 20-62 years in 1990 participated in postal ..
  8. Yearsley J, Viard F, Broquet T. The effect of collective dispersal on the genetic structure of a subdivided population. Evolution. 2013;67:1649-59 pubmed publisher
    Correlated dispersal paths between two or more individuals are widespread across many taxa. The population genetic implications of this collective dispersal have received relatively little attention...
  9. Krehenwinkel H, Tautz D. Northern range expansion of European populations of the wasp spider Argiope bruennichi is associated with global warming-correlated genetic admixture and population-specific temperature adaptations. Mol Ecol. 2013;22:2232-48 pubmed publisher
    ..Hence, global warming could have facilitated the initial admixture of populations and this resulted in genetic lineages with new habitat preferences. ..

More Information


  1. Gaughan A, Stevens F, Linard C, Jia P, Tatem A. High resolution population distribution maps for Southeast Asia in 2010 and 2015. PLoS ONE. 2013;8:e55882 pubmed publisher
    Spatially accurate, contemporary data on human population distributions are vitally important to many applied and theoretical researchers...
  2. Holm L, Hansen D, Larsen P, Johansen C, Vedsted P, Bergholdt S, et al. Social inequality in cancer rehabilitation: a population-based cohort study. Acta Oncol. 2013;52:410-22 pubmed publisher
    ..A population-based cohort study including incident cancer patients diagnosed from 1 October 2007 to 30 September 2008 in ..
  3. Ross L, Hardy N, Okusu A, Normark B. Large population size predicts the distribution of asexuality in scale insects. Evolution. 2013;67:196-206 pubmed publisher
    ..A number of models have indicated that population size might play a crucial role in the evolution of asexuality...
  4. Krieger N. Who and what is a "population"? Historical debates, current controversies, and implications for understanding "population health" and rectifying health inequities. Milbank Q. 2012;90:634-81 pubmed publisher
    The idea of "population" is core to the population sciences but is rarely defined except in statistical terms...
  5. Fadini G, Marcuzzo G, Marescotti M, de Kreutzenberg S, Avogaro A. Elevated white blood cell count is associated with prevalence and development of the metabolic syndrome and its components in the general population. Acta Diabetol. 2012;49:445-51 pubmed publisher
    ..of white blood cell (WBC) count with prevalence and development of the MS and its components in the general population. A cohort of 1,329 subjects from the local working population aged 41.3 ± 7...
  6. Luciano M, Evans D, Hansell N, Medland S, Montgomery G, Martin N, et al. A genome-wide association study for reading and language abilities in two population cohorts. Genes Brain Behav. 2013;12:645-52 pubmed publisher
    ..Here, we report a genome-wide association meta-analysis of two large cohorts: population samples of Australian twins and siblings aged 12-25?years (n?=?1177 from 538 families), and a younger cohort of ..
  7. Cerigo H, Coutlee F, Franco E, Brassard P. Dry self-sampling versus provider-sampling of cervicovaginal specimens for human papillomavirus detection in the Inuit population of Nunavik, Quebec. J Med Screen. 2012;19:42-8 pubmed publisher
    ..Women in this population were easily able to collect adequate cervicovaginal specimens for HPV testing...
  8. Browning B, Browning S. Improving the accuracy and efficiency of identity-by-descent detection in population data. Genetics. 2013;194:459-71 pubmed publisher
    ..To investigate the properties of Refined IBD, we simulate SNP data from a model with recent superexponential population growth that is designed to match United Kingdom data...
  9. Hickey J, Kinghorn B, Tier B, van der Werf J, Cleveland M. A phasing and imputation method for pedigreed populations that results in a single-stage genomic evaluation. Genet Sel Evol. 2012;44:9 pubmed publisher
  10. Makroo R, Bhatia A, Gupta R, Phillip J. Prevalence of Rh, Duffy, Kell, Kidd & MNSs blood group antigens in the Indian blood donor population. Indian J Med Res. 2013;137:521-6 pubmed
    ..data are available regarding the frequencies of the blood group antigens other than ABO and RhD in the Indian population. Knowledge of the antigen frequencies is important to assess risk of antibody formation and to guide the ..
  11. Friedrich N, Jørgensen T, Juul A, Spielhagen C, Nauck M, Wallaschofski H, et al. Insulin-like growth factor I and anthropometric parameters in a Danish population. Exp Clin Endocrinol Diabetes. 2012;120:171-4 pubmed publisher
    ..of the present study was to analyse the associations between anthropometric measures and IGF-I levels in a population-based sample...
  12. Pausch H, Aigner B, Emmerling R, Edel C, Götz K, Fries R. Imputation of high-density genotypes in the Fleckvieh cattle population. Genet Sel Evol. 2013;45:3 pubmed publisher
    ..The data set was divided into a reference and a validation population. Genotypes for all SNP except those included in the BovineSNP50 Bead chip were masked and subsequently imputed ..
  13. Leroy G, Mary Huard T, Verrier E, Danvy S, Charvolin E, Danchin Burge C. Methods to estimate effective population size using pedigree data: Examples in dog, sheep, cattle and horse. Genet Sel Evol. 2013;45:1 pubmed publisher
    Effective population sizes of 140 populations (including 60 dog breeds, 40 sheep breeds, 20 cattle breeds and 20 horse breeds) were computed using pedigree information and six different computation methods...
  14. Reidenbach K, Neafsey D, Costantini C, Sagnon N, Simard F, Ragland G, et al. Patterns of genomic differentiation between ecologically differentiated M and S forms of Anopheles gambiae in West and Central Africa. Genome Biol Evol. 2012;4:1202-12 pubmed publisher
    ..genotyping array to characterize patterns of genomic differentiation between four geographically paired M and S population samples from West and Central Africa...
  15. Goffredo P, Roman S, Sosa J. Hurthle cell carcinoma: a population-level analysis of 3311 patients. Cancer. 2013;119:504-11 pubmed publisher
    ..To date, there is a paucity of data at a population level...
  16. Kruger A, Lossius H, Mikkelsen S, Kurola J, Castren M, Skogvoll E. Pre-hospital critical care by anaesthesiologist-staffed pre-hospital services in Scandinavia: a prospective population-based study. Acta Anaesthesiol Scand. 2013;57:1175-85 pubmed publisher
    ..This population-based, prospective study recorded activity in 16 anaesthesiologist-staffed pre-hospital services in Denmark, ..
  17. Pickrell J, Pritchard J. Inference of population splits and mixtures from genome-wide allele frequency data. PLoS Genet. 2012;8:e1002967 pubmed publisher
    ..In this paper, we present a statistical model for inferring the patterns of population splits and mixtures in multiple populations...
  18. Qureshi M, Jan N, Dar N, Hussain M, Andrabi K. A novel p16(INK4A) mutation associated with esophageal squamous cell carcinoma in a high risk population. Biomarkers. 2012;17:552-6 pubmed publisher
    ..sequence variants and their potential association with esophageal squamous cell carcinoma (ESCC) in a high risk population from Kashmir, India...
  19. Kidd J, Gravel S, Byrnes J, Moreno Estrada A, Musharoff S, Bryc K, et al. Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation. Am J Hum Genet. 2012;91:660-71 pubmed publisher
    Full sequencing of individual human genomes has greatly expanded our understanding of human genetic variation and population history...
  20. Yeh C, Chen T, Hu C, Chiu W, Liao C. Risk of epilepsy after traumatic brain injury: a retrospective population-based cohort study. J Neurol Neurosurg Psychiatry. 2013;84:441-5 pubmed publisher
    To investigate the associated risk of epilepsy after traumatic brain injury (TBI) in a population-based retrospective cohort study...
  21. Sainz J, Serrano R, Borrero C, Turmo E. First trimester contingent test as a screening method for Down's syndrome. A prospective study in the general population. J Matern Fetal Neonatal Med. 2012;25:2221-4 pubmed publisher
    ..6-88.9) (17/24) with an FPR of 3% (95% CI; 2.7-3.3) (316/10,430) and 2% (95% CI; 1.7-2.3) (220/10,408), respectively. With the contingent test, we managed to reduce the FPR, but the Sen was too low for use as a screening method for DS. ..
  22. Poh Y, Ting C, Fu H, Langley C, Begun D. Population genomic analysis of base composition evolution in Drosophila melanogaster. Genome Biol Evol. 2012;4:1245-55 pubmed publisher
    ..However, no such pattern was observed for comparable base composition polymorphisms in noncoding DNA. These results suggest that AT-ending codons could currently be favored by natural selection in the D. melanogaster lineage. ..
  23. Carlé A, Knudsen N, Pedersen I, Perrild H, Ovesen L, Rasmussen L, et al. Determinants of serum T4 and T3 at the time of diagnosis in nosological types of thyrotoxicosis: a population-based study. Eur J Endocrinol. 2013;169:537-45 pubmed publisher
    To characterize thyroid hormone levels at the time of diagnosis in the nosological types of thyrotoxicosis diagnosed in the population and to analyze determinants for serum thyroxine (T4) and tri-iodothyronine (T3).
  24. Thuret R, Sun M, Budaus L, Abdollah F, Liberman D, Shariat S, et al. A population-based analysis of the effect of marital status on overall and cancer-specific mortality in patients with squamous cell carcinoma of the penis. Cancer Causes Control. 2013;24:71-9 pubmed publisher
    ..The association between marital status and tumor stage and grade, as well as overall mortality (OM) and cancer-specific mortality (CSM) received little attention in patients with squamous cell carcinoma of the penis (SCCP)...
  25. Bezerra de Souza D, Jerez Roig J, Bernal M. Laryngeal cancer survival in Zaragoza (Spain): a population-based study. Clin Transl Oncol. 2012;14:221-4 pubmed publisher
    This article aims to study larynx cancer survival from the Population-Based Cancer Registry of Zaragoza, Spain, for the period 1978-2002.
  26. Subramanian S. Significance of population size on the fixation of nonsynonymous mutations in genes under varying levels of selection pressure. Genetics. 2013;193:995-1002 pubmed publisher
    ..observed a higher ratio of divergences at nonsynonymous and synonymous sites (? = dN/dS) in species with a small population size compared to that estimated for those with a large population size...
  27. Vereczkey A, Kósa Z, Csaky Szunyogh M, Urban R, Czeizel A. Birth outcomes of cases with left-sided obstructive defects of the heart in the function of maternal socio-demographic factors: a population-based case-control study. J Matern Fetal Neonatal Med. 2012;25:2536-41 pubmed publisher
    ..Live-born infants were selected from the population-based large dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities, and 302 cases with ..
  28. Ross R, Greenhill S, Atkinson Q. Population structure and cultural geography of a folktale in Europe. Proc Biol Sci. 2013;280:20123065 pubmed publisher
    Despite a burgeoning science of cultural evolution, relatively little work has focused on the population structure of human cultural variation...
  29. Liu Y, Chen C, Liao L, Wan L, Tsai C, Tsai F. Association of IL12B polymorphisms with susceptibility to Graves ophthalmopathy in a Taiwan Chinese population. J Biomed Sci. 2012;19:97 pubmed publisher
    ..A Taiwan Chinese population comprising 200 GD patients with GO and 271 GD patients without GO was genotyped using an allele-specific ..
  30. Logan R, Robledo R, Recla J, Philip V, Bubier J, Jay J, et al. High-precision genetic mapping of behavioral traits in the diversity outbred mouse population. Genes Brain Behav. 2013;12:424-37 pubmed publisher
    ..The newly developed Diversity Outbred (DO) population promises to deliver improved resolution that will circumvent costly fine-mapping studies...
  31. Liu L, Zhang D, Liu H, Arendt C. Robust methods for population stratification in genome wide association studies. BMC Bioinformatics. 2013;14:132 pubmed publisher
    ..In such studies, it is very important to correct for population stratification, which refers to allele frequency differences between cases and controls due to systematic ..
  32. Glodzik D, Navarro P, Vitart V, Hayward C, McQuillan R, Wild S, et al. Inference of identity by descent in population isolates and optimal sequencing studies. Eur J Hum Genet. 2013;21:1140-5 pubmed publisher
    In an isolated population, individuals are likely to share large genetic regions inherited from common ancestors...
  33. Haj Mouhamed D, Ezzaher A, Neffati F, Douki W, Gaha L, Najjar M. [Risk of hyperthyroidism in a Tunisian population of smokers]. Ann Biol Clin (Paris). 2012;70:199-206 pubmed publisher
    ..This study aimed to examine the effect of cigarette smoking on thyroid function especially TSH and FT4 levels and to determine the correlation between these parameters and the biological tobacco markers: plasma thiocyanate and cotininuria...
  34. Friedrich N, Thuesen B, Jørgensen T, Juul A, Spielhagen C, Wallaschofksi H, et al. The association between IGF-I and insulin resistance: a general population study in Danish adults. Diabetes Care. 2012;35:768-73 pubmed publisher
    ..the current study was to evaluate the association between IGF-I level and insulin resistance in a Danish general population. Included were 3,354 adults, aged 19-72 years, from the cross-sectional Health2006 study...
  35. Kotz D, Brown J, West R. Effectiveness of varenicline versus nicotine replacement therapy for smoking cessation with minimal professional support: evidence from an English population study. Psychopharmacology (Berl). 2014;231:37-42 pubmed publisher
    ..The comparative effectiveness of varenicline when prescribed under routine circumstances and in the general population has not been tested. To compare the abstinence rates of smokers trying to stop having used varenicline vs...
  36. Ramis J, Artigas C, Santiago M, Mañes F, Canonge R, Comas L. Is there a relationship between TSH levels and diabetic retinopathy in the Caucasian population?. Diabetes Res Clin Pract. 2012;97:e45-7 pubmed publisher
    ..hypothyroidism (SCH) and diabetic retinopathy (DR) reported in Asiatic type 2 diabetic populations also occurs in the Caucasian population. We could not find any relationship between either TSH levels or the presence of SCH and DR.
  37. Chou W, Hung Y, Hsu J, Chen J, Lu C, Hwang T, et al. Chromogranin A is a reliable biomarker for gastroenteropancreatic neuroendocrine tumors in an Asian population of patients. Neuroendocrinology. 2012;95:344-50 pubmed publisher
    ..To evaluate the significance of plasma chromogranin A (CgA) levels in patients with gastroenteropancreatic neuroendocrine tumors (GEP-NET) in terms of disease status and treatment responses...
  38. Zhou L, Ding X, Zhang Q, Wang Y, Lund M, Su G. Consistency of linkage disequilibrium between Chinese and Nordic Holsteins and genomic prediction for Chinese Holsteins using a joint reference population. Genet Sel Evol. 2013;45:7 pubmed publisher
    In China, the reference population of genotyped Holstein cattle is relatively small with to date, 80 bulls and 2091 cows genotyped with the Illumina 54?K chip...
  39. Ahacic K, Kåreholt I, Helgason A, Allebeck P. Non-response bias and hazardous alcohol use in relation to previous alcohol-related hospitalization: comparing survey responses with population data. Subst Abuse Treat Prev Policy. 2013;8:10 pubmed publisher
    ..b>Population data corresponding to the surveys were derived from the Stockholm County registry...
  40. Krogenæs A, Rootwelt V, Larsen S, Sjøberg E, Akselsen B, Skår T, et al. A serologic study of canine herpes virus-1 infection in the Norwegian adult dog population. Theriogenology. 2012;78:153-8 pubmed publisher
    ..In conclusion, this study strongly indicates that CHV1 infection is endemic in the dog population of Norway. There are significant differences in seroprevalence between geographic regions in the country.
  41. Shao H, Bellos E, Yin H, Liu X, Zou J, Li Y, et al. A population model for genotyping indels from next-generation sequence data. Nucleic Acids Res. 2013;41:e46 pubmed publisher
    ..We introduce an efficient population clustering algorithm for diploids and polyploids which was tested on a dataset of 2000 exomes...
  42. Larcombe L, Mookherjee N, Slater J, Slivinski C, Singer M, Whaley C, et al. Vitamin D in a northern Canadian first nation population: dietary intake, serum concentrations and functional gene polymorphisms. PLoS ONE. 2012;7:e49872 pubmed publisher
    ..VDBP and VDR polymorphisms, and low winter 25-OHD(3) serum concentrations may be risk factors for infectious diseases and chronic conditions related to the dysregulation of the vitamin D pathway. ..
  43. Shi D, Li P, Ma L, Zhong D, Chu H, Yan F, et al. A genetic variant in pre-miR-27a is associated with a reduced renal cell cancer risk in a Chinese population. PLoS ONE. 2012;7:e46566 pubmed publisher
    ..to investigate whether SNP rs895819 was associated with the development of renal cell cancer (RCC) in a Chinese population. In this case-control study, we recruited 594 RCC patients and 600 cancer-free controls with frequency matched ..
  44. Purcell J, Chapuisat M. Bidirectional shifts in colony queen number in a socially polymorphic ant population. Evolution. 2013;67:1169-80 pubmed publisher
    ..Our study population of Formica selysi has single- and multiple-queen colonies...
  45. Bejot Y, Aboa Eboulé C, Jacquin A, Troisgros O, Hervieu M, Durier J, et al. Stroke care organization overcomes the deleterious 'weekend effect' on 1-month stroke mortality: a population-based study. Eur J Neurol. 2013;20:1177-83 pubmed publisher
    ..All cases of stroke and TIA from 1985 to 2010 were identified from a population-based registry, using multiple overlapping sources of information. Demographics and clinical data were recorded...
  46. Tonks A, Gornall A, Larkins S, Gardosi J. Trisomies 18 and 13: trends in prevalence and prenatal diagnosis - population based study. Prenat Diagn. 2013;33:742-50 pubmed publisher
    ..We conducted a cohort study from a population-based regional anomaly register covering 995?003 births (1995-2009). There were 786 affected cases...
  47. Brennan A, Harris S, Hiscock S. The population genetics of sporophytic self-incompatibility in three hybridizing senecio (asteraceae) species with contrasting population histories. Evolution. 2013;67:1347-67 pubmed publisher
    ..This study investigates the SI mating systems of three hybridizing Senecio species with contrasting population histories. Senecio aethnensis and S...
  48. Ionita Laza I, Lee S, Makarov V, Buxbaum J, Lin X. Family-based association tests for sequence data, and comparisons with population-based association tests. Eur J Hum Genet. 2013;21:1158-62 pubmed publisher
    ..of sequence-based association tests for family-based designs that corresponds naturally to previously proposed population-based tests, including the classical Burden and variance-component tests...
  49. Fiume M, Smith E, Brook A, Strbenac D, Turner B, Mezlini A, et al. Savant Genome Browser 2: visualization and analysis for population-scale genomics. Nucleic Acids Res. 2012;40:W615-21 pubmed publisher
    ..The Savant Genome Browser is freely available (open source) at www.savantbrowser.com. ..
  50. Fischer B, Lusted A, Roerecke M, Taylor B, Rehm J. The prevalence of mental health and pain symptoms in general population samples reporting nonmedical use of prescription opioids: a systematic review and meta-analysis. J Pain. 2012;13:1029-44 pubmed publisher
    ..review, and meta-analysis were completed separately for both mental health problem symptoms and pain in general population samples reporting NMPOU. Overall, 9 unique epidemiological studies were identified and included in the review...
  51. Goli S, Arokiasamy P. Demographic transition in India: an evolutionary interpretation of population and health trends using 'change-point analysis'. PLoS ONE. 2013;8:e76404 pubmed publisher
    Lack of a robust analytical tool for trend analysis of population and health indicators is the basic rationale of this study...
  52. Kelly P, Crispino G, Sheehan O, Kelly L, Marnane M, Merwick A, et al. Incidence, event rates, and early outcome of stroke in Dublin, Ireland: the North Dublin population stroke study. Stroke. 2012;43:2042-7 pubmed publisher
    The World Health Organization has emphasized the importance of international population-based data for unbiased surveillance of stroke incidence and outcome...
  53. Maruyama H, Yasui T, Ishikawa Fujiwara T, Morii E, Yamamoto Y, Yoshii T, et al. Human papillomavirus and p53 mutations in head and neck squamous cell carcinoma among Japanese population. Cancer Sci. 2014;105:409-17 pubmed publisher