dansyl compounds


Summary: Compounds that contain a 1-dimethylaminonaphthalene-5-sulfonyl group.

Top Publications

  1. Niemann A, Baltes J, Elsasser H. Fluorescence properties and staining behavior of monodansylpentane, a structural homologue of the lysosomotropic agent monodansylcadaverine. J Histochem Cytochem. 2001;49:177-85 pubmed
    ..Therefore, dansylated aminopentane can be used as a specific marker for autophagic vacuoles in vivo and in fixed cells.(J Histochem Cytochem 49:177-185, 2001) ..
  2. el Enany N, Belal F, Rizk M. Spectrofluorimetric determination of oxamniquine in dosage forms and spiked human plasma through derivatization with 1-dimethylaminonaphthalene-5-sulphonyl chloride. J Fluoresc. 2008;18:349-55 pubmed
    ..Furthermore, the method was applied for the determination of oxamniquine in spiked human plasma, the mean % recovery (n = 4) is 97.77 +/- 1.19. A proposal of the reaction pathway was presented. ..
  3. Chen Y, Guo L. Fluorescence study on site-specific binding of perfluoroalkyl acids to human serum albumin. Arch Toxicol. 2009;83:255-61 pubmed publisher
    ..5 x 10(6) M(-1) and 1.2 x 10(6) M(-1), whereas PFBA did not bind. The data were compared with fatty acids to evaluate the potential toxicological effect of these environmental chemicals. ..
  4. Lissi E, Alicia Biasutti M, Abuin E, Leon L. A fluorescence study of human serum albumin binding sites modification by hypochlorite. J Photochem Photobiol B. 2009;94:77-81 pubmed publisher
    ..These characteristics of the sites remain even after extensive treatment with hypochlorite. This stubbornness of HSA could allow the protein to maintain its function along its in vivo lifetime. ..
  5. Ma Y, Xiang F, Jin W, Yu L. Determination of total glutathione in yeasts by high-performance liquid chromatography with dansylation. Z Naturforsch C. 2010;65:391-4 pubmed
    ..5, 60 degrees C for 60 min and assayed by HPLC. GSHt in Saccharomyces cerevisiae is higher than in Candida rugosa and Candida utilis. S. cerevisiae can be chosen as the better target for mutagenesis and industrial scale. ..
  6. Yamasaki K, Maruyama T, Kragh Hansen U, Otagiri M. Characterization of site I on human serum albumin: concept about the structure of a drug binding site. Biochim Biophys Acta. 1996;1295:147-57 pubmed
    ..Furthermore, the relation between these regions and the high-affinity binding sites for other drugs have been discussed. ..
  7. Kennedy M, Garside L, Goodrick L, McDermott L, Brass A, Price N, et al. The Ov20 protein of the parasitic nematode Onchocerca volvulus. A structurally novel class of small helix-rich retinol-binding proteins. J Biol Chem. 1997;272:29442-8 pubmed
    ..The retinol binding activity of Ov20 could possibly contribute to the eye defects associated with onchocerciasis and, because there is no counterpart in mammals, represents a strategic target for chemotherapy. ..
  8. Sakai T, Yamasaki K, Sako T, Kragh Hansen U, Suenaga A, Otagiri M. Interaction mechanism between indoxyl sulfate, a typical uremic toxin bound to site II, and ligands bound to site I of human serum albumin. Pharm Res. 2001;18:520-4 pubmed
    ..5) binding of these molecules was nearly "independent". The present data provide useful information for elucidating a potential mechanism of interaction between drugs and endogenous substances including uremic toxins. ..
  9. Bagdonaite K, Viklund G, Skog K, Murkovic M. Analysis of 3-aminopropionamide: a potential precursor of acrylamide. J Biochem Biophys Methods. 2006;69:215-21 pubmed
    ..In coffee 3-APA was not formed, neither in green nor in roasted beans. ..

More Information

Publications106 found, 100 shown here

  1. Ringer L, Sirajuddin P, Yenugonda V, Ghosh A, DiVito K, Trabosh V, et al. VMY-1-103, a dansylated analog of purvalanol B, induces caspase-3-dependent apoptosis in LNCaP prostate cancer cells. Cancer Biol Ther. 2010;10:320-5 pubmed
  2. Yenugonda V, Deb T, Grindrod S, Dakshanamurthy S, Yang Y, Paige M, et al. Fluorescent cyclin-dependent kinase inhibitors block the proliferation of human breast cancer cells. Bioorg Med Chem. 2011;19:2714-25 pubmed publisher
    ..Fluorescent CDK inhibitors offer potential as novel theranostic agents, combining therapeutic and diagnostic properties in the same molecule. ..
  3. Ringer L, Sirajuddin P, Heckler M, Ghosh A, Suprynowicz F, Yenugonda V, et al. VMY-1-103 is a novel CDK inhibitor that disrupts chromosome organization and delays metaphase progression in medulloblastoma cells. Cancer Biol Ther. 2011;12:818-26 pubmed publisher
    ..Our data suggest that VMY-1-103 possesses unique antiproliferative capabilities and that this compound may form the basis of a new candidate drug to treat medulloblastoma. ..
  4. Swenson R, Williams C, Massey V. Identification of the histidine residue in D-amino acid oxidase that is covalently modified during inactivation by 5-dimethylaminonaphthalene-1-sulfonyl chloride. J Biol Chem. 1983;258:497-502 pubmed
  5. Luzardo M, Bernik D, Pazos I, Figueroa S, Lanio M, Verez V, et al. Phase and surface properties of lipid bilayers containing neoglycolipids. Arch Biochem Biophys. 1999;363:81-90 pubmed
    ..It is concluded that a relatively low proportion of neoglycolipids affects significantly the interfacial properties of DPPC bilayers in large unilamellar vesicles in the absence of changes at the membrane bulk at 25 degrees C. ..
  6. Latif O, Peterson J, Waltenbaugh C. Alcohol-mediated polarization of type 1 and type 2 immune responses. Front Biosci. 2002;7:a135-47 pubmed
    ..Further ethanol consumption leads to decrease affinity of the IgG2a and IgG2b Th1-regulated antibody isotypes. ..
  7. Shen B, Xiang Z, Miller B, Louie G, Wang W, Noel J, et al. Genetically encoding unnatural amino acids in neural stem cells and optically reporting voltage-sensitive domain changes in differentiated neurons. Stem Cells. 2011;29:1231-40 pubmed publisher
    ..The method described here should be generally applicable to other stem cells and membrane proteins. ..
  8. Davies J, Thumser A, Wilton D. Binding of recombinant rat liver fatty acid-binding protein to small anionic phospholipid vesicles results in ligand release: a model for interfacial binding and fatty acid targeting. Biochemistry. 1999;38:16932-40 pubmed
    ..The conformational change linked to interfacial binding of this protein could provide a mechanism for fatty acid targeting within the cell. ..
  9. Zeng W, Yao M, Townsend D, Kabalka G, Wall J, Le Puil M, et al. Synthesis, biological evaluation and radiochemical labeling of a dansylhydrazone derivative as a potential imaging agent for apoptosis. Bioorg Med Chem Lett. 2008;18:3573-7 pubmed publisher
    ..The straightforward preparation of fluorine-18 labeled 3 makes it a promising tracer for PET imaging of apoptosis. ..
  10. Huang X, Chen J, He L, Kang X. [Detection of monoamine neurotransmitters and its metabolites by high performance liquid chromatograph after pre-column derivatization of dansyl chloride column]. Zhonghua Yu Fang Yi Xue Za Zhi. 2012;46:1117-20 pubmed
    ..The method to detect monoamine neurotransmitters and its metabolites by HPLC and pre-column derivatization with dansyl chloride was established; and this method could provide reference for the detection of polyamine by HPLC. ..
  11. Kim K, Kim H, Moon D, Rhee Y, Kim B. (DNS)C: a fluorescent, environmentally sensitive cytidine derivative for the direct detection of GGG triad sequences. Org Biomol Chem. 2013;11:5605-14 pubmed publisher
    ..The environmental sensitivity of (DNS)C can be exploited as a fluorescence tool for monitoring the interactions of DNA with other biomolecules, including DNA, RNA, and proteins. ..
  12. Adachi H, Katayama T, Nakazato H, Tsujimoto M. Importance of Glu-125 in the catalytic activity of human renal dipeptidase. Biochim Biophys Acta. 1993;1163:42-8 pubmed
    ..In contrast, Asp-125-hrDP and Cys-125hrDP were found to be inactive (< or = 0.1% of wild-type enzyme). These results suggest that the polarity and/or length of the side chain of Glu-125 residue are important for the enzyme activity. ..
  13. Ramani D, Nakib S, Chen H, Garbay C, Loukaci A, Cynober L, et al. N-Carbamoylputrescine, a citrulline-derived polyamine, is not a significant citrulline metabolite in rats. Anal Biochem. 2012;423:54-60 pubmed publisher
    ..We failed to detect NCP in these animals. These data suggest that NCP is not a significant citrulline metabolite in rats. ..
  14. Przybylski P, Bejcar G, Huczyński A, Schroeder G, Brzezinski B, Bartl F. 1H- and 13C-NMR, FTIR, UV-VIS, ESI-MS, and PM5 studies as well as emission properties of a new Schiff base of gossypol with 5-methoxytryptamine and a new hydrazone of gossypol with dansylhydrazine. Biopolymers. 2006;82:521-35 pubmed
    ..The structures of the stable tautomers are calculated and visualized using the PM5 semiempirical method. The intra- and intermolecular hydrogen bonds within these structures are discussed...
  15. Licea Perez H, Wang S, Bowen C. Development of a sensitive and selective LC-MS/MS method for the determination of alpha-fluoro-beta-alanine, 5-fluorouracil and capecitabine in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2009;877:1040-6 pubmed publisher
    ..The results from assay validation show that the method is rugged, precise, accurate, and well suited to support pharmacokinetic studies where approximately 300 samples can be extracted and analyzed in 1 day. ..
  16. Gasymov O, Abduragimov A, Glasgow B. Intracavitary ligand distribution in tear lipocalin by site-directed tryptophan fluorescence. Biochemistry. 2009;48:7219-28 pubmed publisher
    ..Although microsecond fluctuations are rate-limiting processes in ligand binding for many proteins, accompanying nanosecond motion may be necessary for propagation of ligand binding. ..
  17. Liu X, Takahashi L, Fitch W, Rozing G, Bayle C, Couderc F. Capillary electrochromatography-laser-induced fluorescence method for separation and detection of dansylated dialkylamine tags in encoded combinatorial libraries. J Chromatogr A. 2001;924:323-9 pubmed
    ..The use of CEC shows promise for miniaturization and multiplexing for future applications, and the use of LIF detection can allow for detection at sub-pmol amounts. ..
  18. Huang M, Burkhoff D, Schachat F, Brandt P. Fluorescence changes on contractile activation in TnC(DANZ) labeled skinned rabbit psoas fibers. J Muscle Res Cell Motil. 2001;22:635-46 pubmed
    ..There is evidence that, in the overlap zone, weakly attached myosin cross-bridges enhance cooperation between the regulatory units of the thin filaments. ..
  19. Sun B, Qi L, Mu X, Qiao J, Wang M. A chiral ligand exchange CE system for monitoring inhibitory effect of kojic acid on tyrosinase. Talanta. 2013;116:1121-5 pubmed publisher
    ..The IC50 of kojic acid obtained from the sigmoidal inhibitory curve was 21.35 ?M. The results imply that the proposed CLE-CE system has the potential in exploring the activity of enzyme and screening the inhibitors of enzyme. ..
  20. Peyri E, Ravelet C, Nicolle E, Villet A, Grosset C, Ravel A, et al. Dansyl amino acid enantiomer separation on a teicoplanin chiral stationary phase: effect of eluent pH. J Chromatogr A. 2001;923:37-43 pubmed
    ..This approach indicated that the chiral discrimination was principally controlled by the interaction between the anionic form of the solute and the stationary phase. ..
  21. Masuko T, Namiki R, Nemoto Y, Miyake M, Kizawa Y, Suzuki T, et al. Neuroprotection by tosyl-polyamine derivatives through the inhibition of ionotropic glutamate receptors. J Pharmacol Exp Ther. 2009;331:522-30 pubmed publisher
    ..1 or 0.5 mg/kg) decreased the seizures induced by intraperitoneal injection of NMDA in mice. These findings indicate that tosyl-polyamine derivatives exhibit neuroprotective effects not only in primary cultured neurons but also in mice. ..
  22. Colombo B, Vidal H, Kamuzora H, Lehmann H. A new haemoglobin J-Habana-alpha71(E20) alanine leads to glutamic acid. Biochim Biophys Acta. 1974;351:1-6 pubmed
  23. Guo Y, Imahori G, Colon L. Hydrolytically stable amino-silica glass coating material for manipulation of the electroosmotic flow in capillary electrophoresis. J Chromatogr A. 1996;744:17-29 pubmed
    ..The reproducibility of the electroosmotic mobility of five different capillaries was found to be 7% R.S.D. The utility of the material is shown with the separation of basic proteins, peptides and basic compounds. ..
  24. Liu P, He W, Qin X, Sun X, Chen H, Zhang S. Synthesis and application of a novel single-isomer mono-6-deoxy-6-((2S,3S)-(+)-2,3-O-isopropylidene-1,4-tetramethylenediamine)-?-cyclodextrin as chiral selector in capillary electrophoresis. Chirality. 2010;22:914-21 pubmed publisher
    ..MIPTACD shows a very good chiral recognition ability even at very low concentrations at the investigated pH values, as shown by the very large values of selectivity and resolution towards amino acids enantiomers to be assessed. ..
  25. Battaglini F, Pallarola D. Two efficient methods for the conjugation of smooth-form lipopolysaccharides with probes bearing hydrazine or amino groups. II. LPS activation with a cyanopyridinium agent. Methods Mol Biol. 2011;739:161-7 pubmed publisher
    ..In the case of horseradish peroxidase, introducing a spacer, a ratio of 29 nmol HRP/mg LPS was obtained, preserving 65% of the original endotoxic activity and an enzymatic activity of 120 U/mg. ..
  26. Bailey M, Thompson E, Millar D. Probing DNA polymerase fidelity mechanisms using time-resolved fluorescence anisotropy. Methods. 2001;25:62-77 pubmed
    ..The important determinants of the proofreading process can therefore be identified by changes made to either the protein or DNA that perturb the partitioning equilibrium and hence alter the magnitude of K(pe). ..
  27. Mercier I, Pham Dang M, Clement R, Gosselin H, Colombo F, Rouleau J, et al. Elevated mean arterial pressure in the ovariectomized rat was normalized by ET(A) receptor antagonist therapy: absence of cardiac hypertrophy and fibrosis. Br J Pharmacol. 2002;136:685-92 pubmed
    ..Lastly, endothelin-1, acting via the stimulation of the ET(A) receptor represents an integral mechanism implicated in the increase of mean arterial pressure following ovariectomy. ..
  28. Kavallieratos K, Rosenberg J, Chen W, Ren T. Fluorescent sensing and selective Pb(II) extraction by a dansylamide ion-exchanger. J Am Chem Soc. 2005;127:6514-5 pubmed
    ..The observed selectivity for Pb(II) is ascribed to the formation of a low-coordinate binary Pb(II)-Sulfonamido complex in the organic phase. ..
  29. Valkó I, Siren H, Riekkola M. Determination of association constants of dansyl-amino acids and beta-cyclodextrin in N-methylformamide by capillary electrophoresis. Electrophoresis. 1997;18:919-23 pubmed
    ..The association constants ranged between 2 and 13 M(-1). ..
  30. Ajayi A, Newaz M, Hercule H, Saleh M, Bode C, Oyekan A. Endothelin-like action of Pausinystalia yohimbe aqueous extract on vascular and renal regional hemodynamics in Sprague Dawley rats. Methods Find Exp Clin Pharmacol. 2003;25:817-22 pubmed
    ..These findings suggest a strong possibility of post-receptor cross-talk between alpha2-adrenoceptors and endothelin, as well as a direct effect of alpha2-adrenoceptors on renal NO production...
  31. Pillai Z, Ceroni P, Kubeil M, Heldt J, Stephan H, Bergamini G. Dendrimers as Nd3+ ligands: effect of generation on the efficiency of the sensitized lanthanide emission. Chem Asian J. 2013;8:771-7 pubmed publisher
    ..It has been observed that an increase in the dendrimer generation as well as the number of amide units enhances the energy transfer to the lanthanide ion. ..
  32. Risley D, Trelli Seifert L, McKenzie Q. Enantiomeric separations of dansyl amino acids using the macrocyclic antibiotic A35512B as a chiral selector in capillary electrophoresis. Electrophoresis. 1999;20:2749-53 pubmed
    ..After optimizing these parameters, the macrocylic antibiotic A35512B provided high resolutions of all the enantiomers for the thirteen dansyl amino acids tested in this study. ..
  33. Cai H, Zhu R, Li H. Determination of dansylated monoamine and amino acid neurotransmitters and their metabolites in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry. Anal Biochem. 2010;396:103-11 pubmed publisher
    ..7% for the interassay. This novel LC-ESI/MS/MS approach is precise, highly sensitive, specific, and sufficiently simple. It can provide an alternative method for the quantification of the NTs and their metabolites in human plasma. ..
  34. Bhalla S, Ali I, Lee H, Andurkar S, Gulati A. Potentiation of oxycodone antinociception in mice by agmatine and BMS182874 via an imidazoline I2 receptor-mediated mechanism. Pharmacol Biochem Behav. 2013;103:550-60 pubmed publisher
    ..We conclude that imidazoline I(2) receptors but not imidazoline I(1) receptors are involved in BMS182874- and agmatine-induced potentiation of oxycodone antinociception in mice. ..
  35. Jorgenson J, Lukacs K. Free-zone electrophoresis in glass capillaries. Clin Chem. 1981;27:1551-3 pubmed
    ..In all cases fluorescent derivatives were necessary for detection. Preliminary results are encouraging, and with further development of sensitive detection devices, applications in clinical analyses may be feasible. ..
  36. De Jong M, Engbersen J, Huskens J, Reinhoudt D. Cyclodextrin dimers as receptor molecules for steroid sensors. Chemistry. 2000;6:4034-40 pubmed
    ..Addition of guests causes a change in fluorescence intensity. ..
  37. Lucas J, Wang D, Sadee W. Calmodulin binding to peptides derived from the i3 loop of muscarinic receptors. Pharm Res. 2006;23:647-53 pubmed
    ..Calmodulin can bind to an M1 region implicated in G protein coupling. This indicates an important role for CaM in the regulation of muscarinic signal transduction. ..
  38. You J, Zhao H, Sun Z, Xia L, Yan T, Suo Y, et al. Application of 10-ethyl-acridine-3-sulfonyl chloride for HPLC determination of aliphatic amines in environmental water using fluorescence and APCI-MS. J Sep Sci. 2009;32:1351-62 pubmed publisher
    ..0-12.7 fmol. The mean intra- and inter-assay precision for all aliphatic amine levels were <3.84 and 3.21%, respectively. Excellent linear responses were observed with coefficients of >0.9995. ..
  39. Hideg E, Kalai T, Hideg K, Vass I. Photoinhibition of photosynthesis in vivo results in singlet oxygen production detection via nitroxide-induced fluorescence quenching in broad bean leaves. Biochemistry. 1998;37:11405-11 pubmed
  40. Al Dirbashi O, Rashed M, Brink H, Jakobs C, Filimban N, Al Ahaidib L, et al. Determination of succinylacetone in dried blood spots and liquid urine as a dansylhydrazone by liquid chromatography tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2006;831:274-80 pubmed
    ..1% with more than 96% recovery. The method was applied retrospectively and prospectively for the diagnosis of hepatorenal tyrosinemia and for follow-up of patients under treatment. ..
  41. Bruschi M, Le Gall J. C-type cytochromes of Desulfovibrio vulgaris. The primary structure of cytochrome c 553. Biochim Biophys Acta. 1972;271:48-60 pubmed
  42. Janini G, Muschik G, Issaq H. Electrokinetic chromatography in suppressed electroosmotic flow environment: use of a charged cyclodextrin for the separation of enantiomers and geometric isomers. Electrophoresis. 1996;17:1575-83 pubmed
    ..The separation of aflatoxin isomers and chlorophenol congeners is presented. In the separation of chlorophenols the more hydrophobic trichlorophenols eluted first and the least hydrophobic, phenol, eluted last. ..
  43. Hernández J, Oliva A, Simon L, Muñiz F, Mateos A, Morán J. Enantioselective chromenone benzoxazole receptor for glutamic acid and its derivatives. J Org Chem. 2003;68:7513-6 pubmed
    ..High association constants were measured for dansylglutamic acid, using a fluorescent method. This receptor can be used for the resolution of the tosylglutamic acid racemic mixture. ..
  44. Li T, Yu Q, Lin B, Feng Y. Synthesis and chromatographic properties of a chiral stationary phase derived from bovine serum albumin immobilized on magnesia-zirconia using phosphonate spacers. J Sep Sci. 2007;30:804-12 pubmed
    ..The coupling reaction in this method was mild, reliable, and reproducible; thus it was also suitable for the immobilization of various biopolymers with amino groups in the preparation of chromatography stationary phases. ..
  45. Sanz M, Castillo G, Hernandez A. Isocratic high-performance liquid chromatographic method for quantitative determination of lysine, histidine and tyrosine in foods. J Chromatogr A. 1996;719:195-201 pubmed
    ..To establish the reliability of the proposed liquid chromatographic (LC) method, the precision and accuracy of the analyses were evaluated using samples of casein and lysozyme. ..
  46. Krivoi I, Drabkina T, Vasil ev A, Kravtsova V, Mandel F. [Analysis of the interaction between nicotinic acetylcholine receptor and Na+,K(+)-ATPase in the rat skeletal muscle and the Torpedo electric organ membrane preparation]. Ross Fiziol Zh Im I M Sechenova. 2006;92:191-203 pubmed
    ..The data obtained suggest that, in two different systems, the interaction between the nicotinic acetylcholine receptor and the Na+,K(+)-ATPase specifically involve the ligand binding sites of these two proteins. ..
  47. Reshef A, Shirvan A, Grimberg H, Levin G, Cohen A, Mayk A, et al. Novel molecular imaging of cell death in experimental cerebral stroke. Brain Res. 2007;1144:156-64 pubmed
    ..DDC may potentially assist in addressing the current "neuroimaging/neurohistology gap", for molecular assessment of the extent of stroke-related cell death. ..
  48. Abo Hashema K, Cake M, Lukas M, Knudsen J. The interaction of acyl-CoA with acyl-CoA binding protein and carnitine palmitoyltransferase I. Int J Biochem Cell Biol. 2001;33:807-15 pubmed
    ..A transfer of acyl-CoA from ACBP-acyl-CoA binary complexes to CPT I could be a result of the enzyme inducing a conformational alteration in the ACBP leading to the release of acyl-CoA. ..
  49. Svatos A, Antonchick A, Schneider B. Determination of brassinosteroids in the sub-femtomolar range using dansyl-3-aminophenylboronate derivatization and electrospray mass spectrometry. Rapid Commun Mass Spectrom. 2004;18:816-21 pubmed
    ..The method could be very useful for the detection of native BS in plant tissue and biosynthetic studies. ..
  50. Das L, Datta A, Gupta S, Poddar A, Sengupta S, Janik M, et al. -NH-dansyl isocolchicine exhibits a significantly improved tubulin-binding affinity and microtubule inhibition in comparison to isocolchicine by binding tubulin through its A and B rings. Biochemistry. 2005;44:3249-58 pubmed
    ..In conclusion, this paper for the first time indicates that a biologically active bifuntional colchicine analogue can be designed where the drug binds tubulin through its A and B rings, while the C ring remains inactive. ..
  51. Tong A, Wu Y, Li L. [Room temperature phosphorimetric determination of practolol with dansyl chloride labeling]. Guang Pu Xue Yu Guang Pu Fen Xi. 1998;18:38-42 pubmed
    ..791 and 0.408ms, respectively. By applying the derivative MS-RTP technique, practolol could be quantitatively determined without previous separation process. Detection limit of practolol with the proposed method was 0.19 microg/mL...
  52. Baker J, Middleton R, Adams L, May L, Briddon S, Kellam B, et al. Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands. Br J Pharmacol. 2010;159:772-86 pubmed publisher
    ..This study evaluated how the physicochemical nature of the linker and the fluorophore affected the pharmacological properties of fluorescent agonists and antagonists...
  53. Zhuang X, Zhong Y, Yuan M, Li H. Pre-column derivatization combined with UHPLC-MS/MS for rapid and sensitive quantification of bakuchiol in rat plasma. J Pharm Biomed Anal. 2013;75:18-24 pubmed publisher
    ..The intravenous and oral pharmacokinetic profiles of bakuchiol were obtained by utilizing this approach. The oral bioavailability of bakuchiol in rats (3.2%) was identified. ..
  54. Wang B, Wan Y, Gao Y, Yang M, Hu J. Determination and characterization of oxy-naphthenic acids in oilfield wastewater. Environ Sci Technol. 2013;47:9545-54 pubmed publisher
  55. Groeneveld G, Kuijer S, de Puit M. Preparation of cyanoacrylate derivatives and comparison of dual action cyanoacrylate formulations. Sci Justice. 2014;54:42-8 pubmed publisher
    ..The initiator of the polymerisation reaction towards novel reagents can be altered according to the need for particular optical properties. ..
  56. Mally A, Witt S. GrpE accelerates peptide binding and release from the high affinity state of DnaK. Nat Struct Biol. 2001;8:254-7 pubmed
  57. Isobe H, Okajima K, Uchiba M, Mizutani A, Harada N, Nagasaki A, et al. Activated protein C prevents endotoxin-induced hypotension in rats by inhibiting excessive production of nitric oxide. Circulation. 2001;104:1171-5 pubmed
    ..Furthermore, such effects of APC were not dependent on its anticoagulant effects but rather on its serine protease activity. ..
  58. Haas J, Fox B. Fluorescence anisotropy studies of enzyme-substrate complex formation in stearoyl-ACP desaturase. Biochemistry. 2002;41:14472-81 pubmed
    ..These results indicate that acyl chain length selectivity derives in major part from partition of the enzyme-substrate complex between substrate release and subsequent steps in catalysis. ..
  59. Kimura E, Aoki S, Kikuta E, Koike T. A macrocyclic zinc(II) fluorophore as a detector of apoptosis. Proc Natl Acad Sci U S A. 2003;100:3731-6 pubmed
    ..Apoptotic detection by 4 has been compared with a presently available Zn(2+) fluorophore, Zinquin 1. We present that 4 has advantages in detection of apoptosis over annexin V-Cy3 and Zinquin 1. ..
  60. Damianovich M, Ziv I, Heyman S, Rosen S, Shina A, Kidron D, et al. ApoSense: a novel technology for functional molecular imaging of cell death in models of acute renal tubular necrosis. Eur J Nucl Med Mol Imaging. 2006;33:281-91 pubmed
    ..The purpose of this study was to test the applicability of these molecules as a diagnostic imaging agent for the detection of renal tubular cell injury following renal ischemia...
  61. Gabaldon M. Thiol dependent isomerization of bovine albumin. Int J Biol Macromol. 2009;44:43-50 pubmed publisher
    ..Aging in the presence of phenylarsine oxide, which complexes vicinal thiols, impairs the formation of isomers and increases the free -SH groups of albumin. ..
  62. Nyland J, Bai J, Katz H, Silbergeld E. In vitro interactions between splenocytes and dansylamide dye-embedded nanoparticles detected by flow cytometry. Nanomedicine. 2009;5:298-304 pubmed publisher
    ..NPs also induced a range of biological signals consistent with activation and costimulation. ..
  63. Levin G, Shirvan A, Grimberg H, Reshef A, Yogev Falach M, Cohen A, et al. Novel fluorescence molecular imaging of chemotherapy-induced intestinal apoptosis. J Biomed Opt. 2009;14:054019 pubmed publisher
  64. Fan Y, Hense M, Ludewig R, Weisgerber C, Scriba G. Capillary electrophoresis-based sirtuin assay using non-peptide substrates. J Pharm Biomed Anal. 2011;54:772-8 pubmed publisher
    ..Resveratrol did not activate sirtuin 1 using the present CE-based enzyme assay. The results indicated that the lysine derivatives can be used in sirtuin assays instead of peptide substrates. ..
  65. Fröhlich R, Furneaux R, Mahuran D, Saf R, Stütz A, Tropak M, et al. 1-Deoxy-D-galactonojirimycins with dansyl capped N-substituents as ?-galactosidase inhibitors and potential probes for GM1 gangliosidosis affected cell lines. Carbohydr Res. 2011;346:1592-8 pubmed publisher
    ..These new compounds are strong inhibitors of d-galactosidases and may serve as leads en route to pharmacological chaperones for GM1-gangliosidosis. ..
  66. Alkhouri B, Denning R, Kim Chiaw P, Eckford P, Yu W, Li C, et al. Synthesis and properties of molecular probes for the rescue site on mutant cystic fibrosis transmembrane conductance regulator. J Med Chem. 2011;54:8693-701 pubmed publisher
    ..This understanding can in turn aid in the design and development of more efficacious compounds which may serve as therapeutic agents in the treatment of cystic fibrosis...
  67. Li C, Dixon J. Human pituitary growth hormone. 32. The primary structure of the hormone: revision. Arch Biochem Biophys. 1971;146:233-6 pubmed
  68. Grove G, Kligman A. Age-associated changes in human epidermal cell renewal. J Gerontol. 1983;38:137-42 pubmed
    ..This suggests that a linear-spline model rather than a simple linear model may be more appropriate for analyzing these results. ..
  69. Hashimoto M, Tsukagoshi K, Nakajima R, Kondo K, Arai A. Microchip capillary electrophoresis using on-line chemiluminescence detection. J Chromatogr A. 2000;867:271-9 pubmed
    ..The present system had advantages in rapid separation time (within 40 s), small (several 10 pI) and accurate sample injection method using a cross-shaped injector, and simplification and miniaturization of the detection device. ..
  70. Fontaniella B, Mateos J, Vicente C, Legaz M. Improvement of the analysis of dansylated derivatives of polyamines and their conjugates by high-performance liquid chromatography. J Chromatogr A. 2001;919:283-8 pubmed
    ..Dansylation is improved at high pH values, whereas removal of phenolics (mainly evernic acid), from the conjugates requires low pH values. ..
  71. Bartzatt R. Fluorescent labeling of drugs and simple organic compounds containing amine functional groups, utilizing dansyl chloride in Na(2)CO(3) buffer. J Pharmacol Toxicol Methods. 2001;45:247-53 pubmed
  72. Gudheti M, Gonzalez Y, Lee S, Wrenn S. Interaction of apolipoprotein A-I with lecithin-cholesterol vesicles in the presence of phospholipase C. Biochim Biophys Acta. 2003;1635:127-41 pubmed
    ..This study supports the possibility of apo A-I solubilizing lipids in bile in a similar fashion as it does in blood and also delineates the mechanism of formation of the complexes. ..
  73. Misra A, Mishra S, Misra K. Synthesis and fluorescence studies of multiple labeled oligonucleotides containing dansyl fluorophore covalently attached at 2'-terminus of cytidine via carbamate linkage. Bioconjug Chem. 2004;15:638-46 pubmed
    ..This is one reason for selecting cytidine for labeling. The results may aid rational design of multiple fluorescent DNA probes for nonradioactive detection of nucleic acids. ..
  74. Bouhss A, Al Dabbagh B, Vincent M, Odaert B, Aumont Nicaise M, Bressolier P, et al. Specific interactions of clausin, a new lantibiotic, with lipid precursors of the bacterial cell wall. Biophys J. 2009;97:1390-7 pubmed publisher
    ..The lantibiotic decreased the mobility of the pentapeptide. Clausin did not interact with the water-soluble UDP-MurNAc- and pyrophosphoryl-MurNAc-pentapeptides, pointing out the importance of the hydrocarbon chain of the lipid target. ..
  75. Rohacova J, Marin M, Martinez Romero A, O Connor J, Gomez Lechon M, Donato M, et al. Synthesis of new, UV-photoactive dansyl derivatives for flow cytometric studies on bile acid uptake. Org Biomol Chem. 2009;7:4973-80 pubmed publisher
    ..These cholic acid analogs are UV photoactive and also exhibit green fluorescence. In addition, they have been demonstrated to be suitable for studying the kinetics of bile acid transport by flow cytometry. ..
  76. Karabacak M, Cinar M, Kurt M, Poiyamozhi A, Sundaraganesan N. The spectroscopic (FT-IR, FT-Raman, UV and NMR) first order hyperpolarizability and HOMO-LUMO analysis of dansyl chloride. Spectrochim Acta A Mol Biomol Spectrosc. 2014;117:234-44 pubmed publisher
    ..Nonlinear optical and thermodynamic properties were interpreted. All the calculated results were compared with the available experimental data of the title molecule. ..
  77. Billsten P, Freskgard P, Carlsson U, Jonsson B, Elwing H. Adsorption to silica nanoparticles of human carbonic anhydrase II and truncated forms induce a molten-globule-like structure. FEBS Lett. 1997;402:67-72 pubmed
    ..The result suggests that surface induced unfolding may give rise to intermediates similar to those for unfolding induced by, for example GuHCl. Thus, the intermediate observed has some features of the molten globule. ..
  78. Jones D, Carlson J, Samiec P, Sternberg P, Mody V, Reed R, et al. Glutathione measurement in human plasma. Evaluation of sample collection, storage and derivatization conditions for analysis of dansyl derivatives by HPLC. Clin Chim Acta. 1998;275:175-84 pubmed
    ..Results from 59 healthy individuals (20-43 years) provided a mean (+/-1 SD) GSH value of 2.09+/-1.14 micromolar. ..
  79. Tamim N, Bennett L, Shellem T, Doerr J. High-performance liquid chromatographic determination of biogenic amines in poultry carcasses. J Agric Food Chem. 2002;50:5012-5 pubmed
    ..The method was linear for all of the amines studied at concentrations ranging from 0.05 to 25 microg/mL. Average recoveries ranged from 92.6% to 96.8% for all amines except for histamine, which was 74.6%. ..
  80. Maraschiello C, Miranda E, Millan E, Floriano P, Vilageliu J. Phenylisothiocyanate and dansyl chloride precolumn derivatizations for the high-performance liquid chromatography analysis of the antitumoral agent ES-285 in dog plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2003;791:1-11 pubmed
    ..On the other hand, the PITC-based procedure characterised by a quite similar LOQ permitted a higher throughput but implied the processing of a 500-microl plasma volume. ..
  81. Kirby B, Shaw G. The neuroprotective effects of N1-dansyl-spermine in the gerbil model of cerebral ischaemia. Brain Res. 2004;1011:74-83 pubmed
    ..This demonstrates that polyamines play a significant role in the neuronal damage produced after cerebral ischaemia, while casting doubt on the suggestion that increased locomotor activity correlates with CA1 pyramidal cell damage. ..
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    ..This study was conducted to evaluate two HPLC derivatization methods for quantitative determination of biogenic amines: the method described by Gonzales de Llano et al. for amino acid analysis and the method described by Eerola et al. ..
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    ..The ETB receptor agonist, IRL1620, produced a similar effect in both placebo and morphine-tolerant rats. This is the first report indicating the involvement of the G-protein-coupled ETA receptor in neonatal morphine tolerance. ..
  84. Gulati A, Bhalla S, Matwyshyn G. A novel combination of opiates and endothelin antagonists to manage pain without any tolerance development. J Cardiovasc Pharmacol. 2004;44 Suppl 1:S129-31 pubmed
    ..A combination use of endothelin antagonist and opiates could provide a novel approach in improving analgesia and eliminating tolerance. ..
  85. Qi L, Zhang S, Zuo M, Chen Y. Capillary electrophoretic determination of glucosamine in osteoarthritis tablets via microwave-accelerated dansylation. J Pharm Biomed Anal. 2006;41:1620-4 pubmed
    ..Recoveries were determined by spiking a known amount of glucosamine in tablet-extracted solutions, giving a range of 88.0-99.7%. The run-to-run relative standard deviation was 0.24% (n=5) for migration time and 2.72% for peak area. ..
  86. Lee M, Kim H, Yoon S, Park N, Kim J. Metal ion induced FRET OFF-ON in tren/dansyl-appended rhodamine. Org Lett. 2008;10:213-6 pubmed
    ..Among 1-3, 1 shows the best FRET efficiency through dansyl emission to rhodamine absorption for the Cu2+ ion. ..
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    ..The results are compared to previous studies of base flipping in DNA containing an abasic site. ..
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    ..It is concluded that both CYP3A4/5 and CYP2C8 play a major role in the formation of TGZ adduct in HLM. However, the contribution of these CYPs varies depending on their relative expression and the concentration of TGZ. ..
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    ..This derivative can be used to characterize lipid-protein and protein-protein interactions of a native-like SP-C in lipid/protein complexes. ..
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    ..This numerical approach is a valuable tool in the exploration of the steric effects implied in the formation of the host-guest complex. ..