chlortetracycline

Summary

Summary: A TETRACYCLINE with a 7-chloro substitution.

Top Publications

  1. Kaul G, Singh S, Gandhi K, Anand S. Calcium requirement and time course of capacitation of goat spermatozoa assessed by chlortetracycline assay. Andrologia. 1997;29:243-51 pubmed
    We standardized chlortetracycline fluorescent assay for studies of calcium requirement and time course of capacitation of goat spermatozoa...
  2. Liu F, Wu J, Ying G, Luo Z, Feng H. Changes in functional diversity of soil microbial community with addition of antibiotics sulfamethoxazole and chlortetracycline. Appl Microbiol Biotechnol. 2012;95:1615-23 pubmed publisher
    ..This paper investigated the changes in microbial functional diversity by spiking sulfamethoxazole (SMX) and chlortetracycline (CTC) in a loam paddy soil and then incubating for 21 days...
  3. Delsol A, Anjum M, Woodward M, Sunderland J, Roe J. The effect of chlortetracycline treatment and its subsequent withdrawal on multi-resistant Salmonella enterica serovar Typhimurium DT104 and commensal Escherichia coli in the pig. J Appl Microbiol. 2003;95:1226-34 pubmed
    To investigate the effect of a therapeutic and sub-therapeutic chlortetracycline treatment on tetracycline-resistant Salmonella enterica serovar Typhimurium DT104 and on the commensal Escherichia coli in pig...
  4. Søeborg T, Ingerslev F, Halling Sørensen B. Chemical stability of chlortetracycline and chlortetracycline degradation products and epimers in soil interstitial water. Chemosphere. 2004;57:1515-24 pubmed
    ..of the potential dominating species of the chlortetracyclines in the environment, the chemical stability of chlortetracycline (CTC) and four major CTC degradation products and epimers (iso-CTC, 4-epi-CTC, anhydro-CTC, and 4-epi-..
  5. Sharma R, Munns K, Alexander T, Entz T, Mirzaagha P, Yanke L, et al. Diversity and distribution of commensal fecal Escherichia coli bacteria in beef cattle administered selected subtherapeutic antimicrobials in a feedlot setting. Appl Environ Microbiol. 2008;74:6178-86 pubmed publisher
    ..The goal of this 197-day study was to investigate the influence of administration of chlortetracycline alone (T) or in combination with sulfamethazine (TS) on the development of resistance, dissemination of ..
  6. Nanduri B, Lawrence M, Boyle C, Ramkumar M, Burgess S. Effects of subminimum inhibitory concentrations of antibiotics on the Pasteurella multocida proteome. J Proteome Res. 2006;5:572-80 pubmed
    ..We analyzed the Pasteurella multocida proteome response to sub-MICs of amoxicillin, chlortetracycline, and enrofloxacin using isotope-coded affinity tags (ICAT)...
  7. Platt T, Loneragan G, Scott H, Norby B, Thomson D, Brown M, et al. Antimicrobial susceptibility of enteric bacteria recovered from feedlot cattle administered chlortetracycline in feed. Am J Vet Res. 2008;69:988-96 pubmed publisher
    To evaluate administration of chlortetracycline in feed of cattle as a method to select for tetracycline resistance among enteric bacteria in feedlot settings. 20 steers...
  8. O Connor A, Poppe C, McEwen S. Changes in the prevalence of resistant Escherichia coil in cattle receiving subcutaneously injectable oxytetracycline in addition to in-feed chlortetracycline compared with cattle receiving only in-feed chlortetracycline. Can J Vet Res. 2002;66:145-50 pubmed
    ..coli from cattle receiving either subcutaneously injectable oxytetracycline in addition to in-feed chlortetracycline or only in-feed chlortetracycline. Resistance to 19 antibiotics was examined...
  9. Kaneto M, Harayama H, Miyake M, Kato S. Capacitation-like alterations in cooled boar spermatozoa: assessment by the chlortetracycline staining assay and immunodetection of tyrosine-phosphorylated sperm proteins. Anim Reprod Sci. 2002;73:197-209 pubmed
    This study was undertaken in order to characterize alterations occurring in cooled boar spermatozoa by a chlortetracycline (CTC) staining assay and immunodetection of tyrosine-phosphorylated sperm proteins...

More Information

Publications94

  1. Nakano T, Miyake K, Endo H, Dairi T, Mizukami T, Katsumata R. Identification and cloning of the gene involved in the final step of chlortetracycline biosynthesis in Streptomyces aureofaciens. Biosci Biotechnol Biochem. 2004;68:1345-52 pubmed publisher
    For chlortetracycline biosynthesis in Streptomyces aureofaciens, the final reduction step is essential to give an antibiotic activity to its intermediate, which is catalyzed by tetracycline dehydrogenase with 7,8-dedimethyl-8-hydroxy-5-..
  2. Chen W, Huang C. Adsorption and transformation of tetracycline antibiotics with aluminum oxide. Chemosphere. 2010;79:779-85 pubmed publisher
    ..Results of this study indicate that aluminum oxide will likely affect the fate of TC antibiotics in the aquatic environment via both adsorption and transformation...
  3. Bravo M, Aparicio I, Garcia Herreros M, Gil M, Pena F, Garcia Marin L. Changes in tyrosine phosphorylation associated with true capacitation and capacitation-like state in boar spermatozoa. Mol Reprod Dev. 2005;71:88-96 pubmed
    ..Capacitation status was assessed by chlortetracycline (CTC) staining...
  4. Cinquina A, Longo F, Anastasi G, Giannetti L, Cozzani R. Validation of a high-performance liquid chromatography method for the determination of oxytetracycline, tetracycline, chlortetracycline and doxycycline in bovine milk and muscle. J Chromatogr A. 2003;987:227-33 pubmed
    ..7-129.9 micro/kg for all compounds in milk and muscle, respectively. The detection capability (CCbeta) was in the range 117.2-131.3 microg/kg and 114.9-133.1 microg/kg for all compounds in milk and muscle, respectively. ..
  5. Jiang S, Lertvorachon J, Hou S, Konishi Y, Webster J, Mealing G, et al. Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia. J Biol Chem. 2005;280:33811-8 pubmed
    ..We examined the protective properties of chlortetracycline (CTC) and demeclocycline (DMC) and showed that these two tetracyclines were also potent neuroprotective ..
  6. Aust M, Godlinski F, Travis G, Hao X, McAllister T, Leinweber P, et al. Distribution of sulfamethazine, chlortetracycline and tylosin in manure and soil of Canadian feedlots after subtherapeutic use in cattle. Environ Pollut. 2008;156:1243-51 pubmed publisher
    ..for the flow of antibiotics into the environment due to common use of antibiotics such as sulfamethazine, chlortetracycline and tylosin...
  7. Ghosh S, LaPara T. The effects of subtherapeutic antibiotic use in farm animals on the proliferation and persistence of antibiotic resistance among soil bacteria. ISME J. 2007;1:191-203 pubmed
    ..b>Chlortetracycline-resistant bacteria were enumerated and characterized from soils exposed to the manure of animals fed ..
  8. Cherlet M, De Backer P, Croubels S. Control of the keto-enol tautomerism of chlortetracycline for its straightforward quantitation in pig tissues by liquid chromatography-electrospray ionization tandem mass spectrometry. J Chromatogr A. 2006;1133:135-41 pubmed
    b>Chlortetracycline (CTC) is a member of the group of the tetracycline antibiotics used in human and veterinary medicine...
  9. Pietrobon E, Domínguez L, Vincenti A, Burgos M, Fornes M. Detection of the mouse acrosome reaction by acid phosphatase. Comparison with chlortetracycline and electron microscopy. J Androl. 2001;22:96-103 pubmed
    ..techniques), Coomassie blue, differential interference contrast or phase contrast, flow cytometry, and chlortetracycline (CTC)...
  10. Carlson J, Mabury S. Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada. Environ Toxicol Chem. 2006;25:1-10 pubmed
    A robust high-throughput method was refined to extract three growth-promoting antibiotics, tylosin (TYL), chlortetracycline (CTC), and monensin (MON), from soil...
  11. Funk J, Lejeune J, Wittum T, Rajala Schultz P. The effect of subtherapeutic chlortetracycline on antimicrobial resistance in the fecal flora of swine. Microb Drug Resist. 2006;12:210-8 pubmed
    The aims of this research were to determine the association between inclusion of subtherapeutic chlortetracycline in the diets of swine and the prevalence and antimicrobial resistance of Salmonella; define the association between ..
  12. Rettedal E, Vilain S, Lindblom S, Lehnert K, Scofield C, George S, et al. Alteration of the ileal microbiota of weanling piglets by the growth-promoting antibiotic chlortetracycline. Appl Environ Microbiol. 2009;75:5489-95 pubmed publisher
    Antibiotics such as chlortetracycline (CTC) have been used to promote growth of pigs for decades, but concerns over increased antibiotic-resistant infections in humans have prompted the development of alternative strategies...
  13. Pils J, Laird D. Sorption of tetracycline and chlortetracycline on K- and Ca-saturated soil clays, humic substances, and clay-humic complexes. Environ Sci Technol. 2007;41:1928-33 pubmed
    Tetracycline (TC) and chlortetracycline (CTC) are used extensively for growth promotion and therapeutic purposes in livestock production...
  14. Cerella C, Mearelli C, De Nicola M, D Alessio M, Magrini A, Bergamaschi A, et al. Analysis of calcium changes in endoplasmic reticulum during apoptosis by the fluorescent indicator chlortetracycline. Ann N Y Acad Sci. 2007;1099:490-3 pubmed
    ..In this study, we performed an image analysis of cells loaded with the fluorescent dye chlortetracycline (CTC) to in situ analyze Ca2+ changes within the ER in apoptosing promonocytic U937 cells...
  15. Muñoz Aguayo J, Lang K, LaPara T, Gonzalez G, Singer R. Evaluating the effects of chlortetracycline on the proliferation of antibiotic-resistant bacteria in a simulated river water ecosystem. Appl Environ Microbiol. 2007;73:5421-5 pubmed
    ..The objective of this study was to estimate the selection potential of chlortetracycline (CTC) on the antibiotic resistance of aerobic bacterial populations in a simulated river water ecosystem...
  16. Brooks S, Kheradpir E, McAllister M, Kwan J, Burgher McLellan K, Kalmokoff M. In-feed administered sub-therapeutic chlortetracycline alters community composition and structure but not the abundance of community resistance determinants in the fecal flora of the rat. Anaerobe. 2009;15:145-54 pubmed publisher
    The impact of continuous sub-therapeutic chlortetracycline on community structure, composition and abundance of tetracycline resistance genes in the rat fecal community was investigated...
  17. Dong X, Gao W, Su J, Tong J, Zhang Q. Effects of dietary polysavone (Alfalfa extract) and chlortetracycline supplementation on antioxidation and meat quality in broiler chickens. Br Poult Sci. 2011;52:302-9 pubmed publisher
    ..the dietary effects of polysavone (0·5, 1·0 and 1·5 g/kg), a natural extract from alfalfa, and 0·15 g/kg chlortetracycline (CTC) on growth performance, antioxidation and meat quality of broiler chickens. 2...
  18. Funk J, Wittum T, Lejeune J, Rajala Schultz P, Bowman A, Mack A. Evaluation of stocking density and subtherapeutic chlortetracycline on Salmonella enterica subsp. enterica shedding in growing swine. Vet Microbiol. 2007;124:202-8 pubmed
    ..The objective of this research was to determine the effect of stocking density and inclusion of subtherapeutic chlortetracycline in the diet on Salmonella fecal prevalence and antimicrobial resistance in growing swine...
  19. Akunda J, Johnson E, Ahrens F, Kramer T. Chlortetracycline modulates acute phase response of ex vivo perfused pig livers, and inhibits TNF-alpha secretion by isolated Kupffer cells. Comp Immunol Microbiol Infect Dis. 2001;24:81-9 pubmed
    ..We investigated the effects of in vivo administration of chlortetracycline (CTC) on ex vivo perfused pig livers...
  20. Zheng D, Chang Q, Gao M, She Z, Jin C, Guo L, et al. Performance evaluation and microbial community of a sequencing batch biofilm reactor (SBBR) treating mariculture wastewater at different chlortetracycline concentrations. J Environ Manage. 2016;182:496-504 pubmed publisher
    The effects of chlortetracycline (CTC) on the performance, microbial activity, extracellular polymeric substances (EPS) and microbial community of a sequencing batch biofilm reactor (SBBR) were investigated in treating mariculture ..
  21. Meng C, Ye Q, Qiu L, Shi X, Su W, Guo Y. [Study on effect of Vitreoscilla hemoglobin gene expression on growth and metabolism of Streptomyces aureofaciens]. Wei Sheng Wu Xue Bao. 2002;42:418-24 pubmed
    ..aureofaciens, and there were no obvious differences between engineering strain and control. The chlortetracycline of engineering strain was 22905 u/mL and of control was 22896 u/mL respectively...
  22. Demerec M. PATTERNS OF BACTERIAL RESISTANCE TO PENICILLIN, AUREOMYCIN, AND STREPTOMYCIN. J Clin Invest. 1949;28:891-3 pubmed
  23. Chen G, Zhao L, Dong Y. [Oxidative kinetics of chlortetracycline by manganese dioxide]. Huan Jing Ke Xue. 2009;30:2773-8 pubmed
    To better understand the transformation of chlortetracycline (CTC) under the oxidation of manganese dioxide (MnO2), kinetics of CTC reaction with MnO2 were investigated and the effects of MnO2 initial concentration, pH, and temperature ..
  24. Wang R, Chen M, Feng F, Zhang J, Sui Q, Tong J, et al. Effects of chlortetracycline and copper on tetracyclines and copper resistance genes and microbial community during swine manure anaerobic digestion. Bioresour Technol. 2017;238:57-69 pubmed publisher
    ..The purpose of this study was thus to investigate effects of both chlortetracycline (CTC) and Cu on reduction of ARGs, heavy metal resistance genes (HMRGs) and mobile genetic elements (MGEs) ..
  25. Bergqvist A, Ballester J, Johannisson A, Lundeheim N, Rodriguez Martinez H. Heparin and dermatan sulphate induced capacitation of frozen-thawed bull spermatozoa measured by merocyanine-540. Zygote. 2007;15:225-32 pubmed
    ..Following exposure of different duration, the spermatozoa were stained with either Chlortetracycline (CTC) or merocyanine-540 and evaluated with epifluorescent light microscopy or flow cytometry, respectively...
  26. Lu L, Wu Y, Ding H, Zhang W. The combined and second exposure effect of copper (II) and chlortetracycline on fresh water algae, Chlorella pyrenoidosa and Microcystis aeruginosa. Environ Toxicol Pharmacol. 2015;40:140-8 pubmed publisher
    ..Microcystis aeruginosa were chosen to test the individual, combined and second exposure effect of Cu(2+) and chlortetracycline (CTC). The 96 h EC50s of each test were calculated, with the ranges of 0.972-15.6 μmol/L (Cu(2+)), 29...
  27. Lin D, Zhou Q, Xu Y, Chen C, Li Y. Physiological and molecular responses of the earthworm (Eisenia fetida) to soil chlortetracycline contamination. Environ Pollut. 2012;171:46-51 pubmed publisher
    This study aims to evaluate toxic effects of exposure to chlortetracycline (CTC) in soil on reproductive endpoints (juvenile counts and cocoon counts), biochemical responses, and genotoxic potentials of the earthworm Eisenia fetida...
  28. Arikan O. Degradation and metabolization of chlortetracycline during the anaerobic digestion of manure from medicated calves. J Hazard Mater. 2008;158:485-90 pubmed publisher
    ..The objective of this study was to determine the fate of chlortetracycline (CTC) during the anaerobic digestion of manure from medicated calves...
  29. Perez Aguirreburualde M, Fernandez S, Cordoba M. Acrosin activity regulation by protein kinase C and tyrosine kinase in bovine sperm acrosome exocytosis induced by lysophosphatidylcholine. Reprod Domest Anim. 2012;47:915-20 pubmed publisher
    ..In cryopreserved bovine spermatozoa, LPC might require modulation, mainly tyrosine kinase participation with respect to PKC activity to induce acrosome exocytosis and increase acrosin activity. ..
  30. Denisenko V, Kuz mina T. [The influence of guanine nucleotides and protein kinase C on Ca2+ from intracellular stores of pigs oocytes stimulated by theophylline and cyclic AMP]. Tsitologiia. 2004;46:557-60 pubmed
    ..stores of pig oocytes, stimulated by theophylline and dbcAMP, was investigated using fluorescent dye chlortetracycline. Effect of cAMP on Ca2+ exit from intracellular stores of pig oocytes was not associated with activation of ..
  31. Thiele Bruhn S. Microbial inhibition by pharmaceutical antibiotics in different soils--dose-response relations determined with the iron(III) reduction test. Environ Toxicol Chem. 2005;24:869-76 pubmed
    ..ED [micromol/kg soil]) for the different antibiotics increased in the order (average ED50 in parentheses) chlortetracycline (53) < sulfadimethoxine (58) < oxytetracycline (170) < sulfadiazine (190) < sulfadimidine (270) =..
  32. Shenghe L, Erhui J, Enmei Q, Guozhong W, Kui L. Chitooligosaccharide promotes immune organ development in broiler chickens and reduces serum lipid levels. Histol Histopathol. 2017;32:951-961 pubmed publisher
    ..while experimental groups I, II, and III were given basic diets for 42 days, supplemented with 50 mg/kg chlortetracycline, 20, and 40 mg/kg chitooligosaccharide, respectively...
  33. Guo L, Chen Y, Zhang L, Yang W, He P. Development and validation of a liquid chromatographic/ tandem mass spectrometric method for determination of chlortetracycline, oxytetracycline, tetracycline, and doxycycline in animal feeds. J AOAC Int. 2012;95:1010-5 pubmed
    A selective and accurate LC/MS/MS method for the simultaneous determination of chlortetracycline (CTC), oxytetracycline (OTC), tetracycline (TC), and doxycycline (DC) in animal feeds was developed...
  34. Ruengsitagoon W. Reverse flow injection spectrophotometric determination of iron(III) using chlortetracycline reagent. Talanta. 2008;74:1236-41 pubmed publisher
    ..It is based on the reaction between iron(III) with chlortetracycline, resulting in an intense yellow complex with a suitable absorption at 435nm...
  35. Tong L, Liu H, Xie C, Li M. Quantitative analysis of antibiotics in aquifer sediments by liquid chromatography coupled to high resolution mass spectrometry. J Chromatogr A. 2016;1452:58-66 pubmed publisher
    ..0m deepness. The exposure to low doses of these compounds in subsurface environment increases concerns on long-term ecological security of underground system. ..
  36. Naidong W, Hua S, Roets E, Hoogmartens J. Assay and purity control of tetracycline, chlortetracycline and oxytetracycline in animal feeds and premixes by TLC densitometry with fluorescence detection. J Pharm Biomed Anal. 2003;33:85-93 pubmed
    ..with fluorescence detection are described for the assay and purity control of tetracycline (TC), chlortetracycline (CTC), and oxytetracycline (OTC) in animal feeds and premixes...
  37. Zong L, Teng D, Wang X, Mao R, Yang N, Hao Y, et al. Mechanism of action of a novel recombinant peptide, MP1102, against Clostridium perfringens type C. Appl Microbiol Biotechnol. 2016;100:5045-57 pubmed publisher
    ..A cell cycle assay demonstrated that MP1102 affected cellular functions, such as DNA synthesis. These results suggested that MP1102 exhibited potential as a new antimicrobial agent against C. perfringens infections. ..
  38. Kwon J. Fate of chlortetracycline in Korean arable soil. Bull Environ Contam Toxicol. 2011;87:36-9 pubmed publisher
    The widespread use of the pharmaceutical chlortetracycline to treat human and animal infectious diseases is raising concern in Korea regarding the potential development of antibiotic-resistant bacteria...
  39. Shintani M, Fukushima N, Tezuka M, Yamane H, Nojiri H. Conjugative transfer of the IncP-7 carbazole degradative plasmid, pCAR1, in river water samples. Biotechnol Lett. 2008;30:117-22 pubmed
    ..The results suggest that the presence of carbazole benefits the appearance of transconjugants belonging to the genus Pseudomonas. Intriguingly, we also detected the transfer of pCAR1 into non-Pseudomonas, Stenotrophomonas-like bacteria. ..
  40. Agga G, Schmidt J, Arthur T. Effects of In-Feed Chlortetracycline Prophylaxis in Beef Cattle on Animal Health and Antimicrobial-Resistant Escherichia coli. Appl Environ Microbiol. 2016;82:7197-7204 pubmed
    Concerns have been raised that in-feed chlortetracycline (CTC) may increase antimicrobial resistance (AMR), specifically tetracycline-resistant (TETr) Escherichia coli and third-generation cephalosporin-resistant (3GCr
  41. Azanu D, Styrishave B, Darko G, Weisser J, Abaidoo R. Occurrence and risk assessment of antibiotics in water and lettuce in Ghana. Sci Total Environ. 2018;622-623:293-305 pubmed publisher
    ..trimethoprim, ampicillin, cefuroxime, sulfamethoxazole, amoxicillin, tetracycline, oxytetracycline, chlortetracycline and doxycycline) were investigated in water and lettuce samples collected in three different areas in Kumasi,..
  42. Davis J, Truman C, Kim S, Ascough J, Carlson K. Antibiotic Transport via Runoff and Soil Loss. J Environ Qual. 2006;35:2250-60 pubmed
    ..An antibiotic solution including tetracycline (TC), chlortetracycline (CTC), sulfathiazole (STZ), sulfamethazine (SMZ), erythromycin (ERY), tylosin (TYL), and monensin (MNS) was ..
  43. Smith E, Munayyer H, Ryan M, Mayles B, Hegde V, Miller G. Direct selection of a specifically blocked mutant of Actinomadura brunnea. Isolation of a third 8-methoxy substituted chlortetracycline. J Antibiot (Tokyo). 1987;40:1419-25 pubmed
    ..The antibiotic produced by the blocked mutant has been identified as 8-methoxychlortetracycline (Sch 36969) based upon its biological activity, relative mobility on TLC and HPLC, and spectroscopic data...
  44. Gil J, Rodríguez Irazoqui M, Lundeheim N, Soderquist L, Rodriguez Martinez H. Fertility of ram semen frozen in Bioexcell and used for cervical artificial insemination. Theriogenology. 2003;59:1157-70 pubmed
    ..Thus, Bioexcell, containing no additives of animal origin, can offer a safer alternative when frozen semen is used for introducing new genetic material into a flock or a country. ..
  45. Zou Q, Peng Z, Zhao Q, Chen H, Cheng Y, Liu Q, et al. Diethylstilbestrol activates CatSper and disturbs progesterone actions in human spermatozoa. Hum Reprod. 2017;32:290-298 pubmed publisher
    ..The sperm acrosome reaction was measured using chlortetracycline staining. The level of tyrosine phosphorylation was determined by western blot assay...
  46. Garcia Herreros M, Aparicio I, Nunez I, Garcia Marin L, Gil M, Peña Vega F. Boar sperm velocity and motility patterns under capacitating and non-capacitating incubation conditions. Theriogenology. 2005;63:795-805 pubmed
    ..Capacitation status was assessed by the chlortetracycline assay after 1 and 3h of incubation. Experiments were repeated five times...
  47. Dong L, Gao J, Xie X, Zhou Q. DNA damage and biochemical toxicity of antibiotics in soil on the earthworm Eisenia fetida. Chemosphere. 2012;89:44-51 pubmed publisher
    ..activities were used as biomarkers to evaluate the genotoxicity and oxidative stress of tetracycline and chlortetracycline on the earthworm Eisenia fetida...
  48. Farkas M, Mojica E, Patel M, Aga D, Berry J. Development of a rapid biolistic assay to determine changes in relative levels of intracellular calcium in leaves following tetracycline uptake by pinto bean plants. Analyst. 2009;134:1594-600 pubmed publisher
    Tetracycline antibiotics, such as chlortetracycline (CTC) and tetracycline (TC), are introduced into agricultural lands through the application of manure as fertilizer...
  49. Wen B, Liu Y, Wang P, Wu T, Zhang S, Shan X, et al. Toxic effects of chlortetracycline on maize growth, reactive oxygen species generation and the antioxidant response. J Environ Sci (China). 2012;24:1099-105 pubmed
    The toxicity of chlortetracycline (CTC) on maize (Zea mays L.) growth and reactive oxygen species (ROS) generation was studied. The root and shoot lengths and fresh weights of maize seedlings were inhibited by CTC treatment (p < 0.05)...
  50. Yeung P, Lam C, Ma Z, Wong Y, Wong J. Involvement of calcium mobilization from caffeine-sensitive stores in mechanically induced cell cycle arrest in the dinoflagellate Crypthecodinium cohnii. Cell Calcium. 2006;39:259-74 pubmed
    ..cohnii cells. In addition, caffeine or shaking mobilized intracellular chlortetracycline (CTC)-positive membrane-bound calcium, which could be similarly depleted by t-BuBHQ, a SERCA pump inhibitor...
  51. Hume M, Donskey C. Effect of Vancomycin, Tylosin, and Chlortetracycline on Vancomycin-Resistant Enterococcus faecium Colonization of Broiler Chickens During Grow-Out. Foodborne Pathog Dis. 2017;14:231-237 pubmed publisher
    ..Chicks received unsupplemented feed or feed containing vancomycin, chlortetracycline, or tylosin from day of hatch to grow-out at 6 weeks...
  52. Shadan S, James P, Howes E, Jones R. Cholesterol efflux alters lipid raft stability and distribution during capacitation of boar spermatozoa. Biol Reprod. 2004;71:253-65 pubmed
    ..A preferential loss of cholesterol from the nonraft pool may be the stimulus that promotes raft clustering over the anterior sperm head. ..
  53. Bachmann S, Menéndez Helman R, Zitta K, Wertheimer E, Miranda P. Replacement of calcium for strontium in hamster sperm incubation media: effect on sperm function. Mol Hum Reprod. 2012;18:22-32 pubmed publisher
    ..We found that sperm undergo the capacitation-related changes in the chlortetracycline (CTC) pattern and tyrosine phosphorylation, and also bind to the zona pellucida (ZP) when using Sr(2+)-..
  54. Coscioni A, Reichenbach H, Schwartz J, LaFalci V, Rodrigues J, Brandelli A. Sperm function and production of bovine embryos in vitro after swim-up with different calcium and caffeine concentration. Anim Reprod Sci. 2001;67:59-67 pubmed
    ..were evaluated: sperm recovery, motility, vigor, morphology, alterations in the pattern of capacitation by chlortetracycline (CTC) staining, and alterations in lysophosphatidyl choline (LPC)-induced acrosome reaction (AR)...
  55. Kaul G, Sharma G, Singh B, Gandhi K. Capacitation and acrosome reaction in buffalo bull spermatozoa assessed by chlortetracycline and Pisum sativum agglutinin fluorescence assay. Theriogenology. 2001;55:1457-68 pubmed
    ..We describe two methods for detecting the acrosomal status of buffalo spermatozoa, namely chlortetracycline (CTC) fluorescence assay and Pisum sativum agglutinin (FITC-PSA) stain...
  56. O Connor A, Ziebell K, Poppe C, McEwen S. Verotoxins in commensal Escherichia coli in cattle: the effect of injectable subcutaneous oxytetracycline in addition to in-feed chlortetracycline on prevalence. Epidemiol Infect. 2004;132:77-85 pubmed
    ..Between samplings all animals received in-feed chlortetracycline for 16 days. Five E...
  57. Stryzhkova H, Kopeĭko O, Lavrinchuk V, Bambura O, Matseliukh B. [Spontaneous and induced variability of Streptomyces aureofaciens--chlortetracycline producer]. Mikrobiol Z. 2002;64:19-23 pubmed
  58. Denisenko V, Kuz mina T, Shokin O. [Dependence of Ca2+ release from intracellular stores on NADH and FAD levels in fertilized and unfertilized bovine oocytes]. Tsitologiia. 2005;47:704-8 pubmed
    ..The obtained data testify that in degenerated zygotes and early embryos Ca2+ release may occur from different intracellular stores. ..
  59. Hathaway M, Dayton W, White M, Pampusch M. Effects of antimicrobials and weaning on porcine serum insulin-like growth factor binding protein levels. J Anim Sci. 2003;81:1456-63 pubmed
    ..8% crude protein and 1.15% lysine with or without Aureozol (110 mg/kg of Aureomycin chlortetracycline, 110 mg/kg of sulfathiazole, and 55 mg/kg of penicillin) for 4 wk...
  60. Kruk I, Lichszteld K, Michalska T, Nizinkiewicz K, Wrońska J. The extra-weak chemiluminescence generated during oxidation of some tetracycline antibiotics. 1. Autoxidation. J Photochem Photobiol B. 1992;14:329-43 pubmed
    ..The data support the concept that, during the autoxidation of TCs, cytotoxic oxygen species such as HO., O2.-, H2O2 and 1O2 are formed. ..
  61. Juntunen P, Laurila T, Heinonen M, Hänninen M. Absence of tetracycline resistance in Campylobacter coli isolates from Finnish finishing pigs treated with chlortetracycline. J Appl Microbiol. 2013;114:974-81 pubmed publisher
    To determine whether therapeutic treatment of pigs with chlortetracycline affects the susceptibility of their Campylobacter isolates for tetracycline, ciprofloxacin and erythromycin...
  62. Bernabo N, Berardinelli P, Mauro A, Russo V, Lucidi P, Mattioli M, et al. The role of actin in capacitation-related signaling: an in silico and in vitro study. BMC Syst Biol. 2011;5:47 pubmed publisher
  63. Cherlet M, Croubels S, De Backer P. Quantitative determination of chlortetracycline content in animal plasma at controlled keto-enol tautomerism by liquid chromatography-electrospray ionization-tandem mass spectrometry. J Chromatogr A. 2006;1102:116-24 pubmed
    b>Chlortetracycline (CTC) is a member of the group of the tetracycline antibiotics used in human and veterinary medicine...
  64. Arijs Y, Vanthournout L, De Clercq P. Preservation of an artificial diet for rearing the predator Orius laevigatus. Meded Rijksuniv Gent Fak Landbouwkd Toegep Biol Wet. 2002;67:467-71 pubmed
    ..05% chlortetracycline was high: growth, survival rate and size of the insect were seriously affected by this antibiotic...
  65. Tournas V, Kohn J, Katsoudas E. The identification of antibacterial compounds for the development of enhanced media for the detection of foodborne fungi. Int J Food Microbiol. 2007;118:83-6 pubmed
    ..tested for their abilities to grow on dichloran rose bengal agar containing various levels of gentamicin, chlortetracycline or chloramphenicol. Results indicated that all fungal isolates except for Rh. glutinis and R...
  66. Gompels L, Smith A, Charles P, Rogers W, Soon Shiong J, Mitchell A, et al. Single-blind randomized trial of combination antibiotic therapy in rheumatoid arthritis. J Rheumatol. 2006;33:224-7 pubmed
    ..Combined antibiotic therapy with intravenous clindamycin and oral tetracycline may be useful in the management of active RA. A double-blind, placebo-controlled trial of therapy is justified. ..
  67. Duff G, Walker D, Malcolm Callis K, Wiseman M, Hallford D. Effects of preshipping vs. arrival medication with tilmicosin phosphate and feeding chlortetracycline on health and performance of newly received beef cattle. J Anim Sci. 2000;78:267-74 pubmed
    ..arrival (ARR) medication with tilmicosin phosphate (MIC; Exp. 1 and 2) and feeding chlortetracycline (CTC; 22 mg/kg of BW from d 5 to 9; Exp. 2) on health and performance of beef calves received in the feedlot...
  68. Tanaka Y, Taguchi S, Yoshida S, Hori S, Takagaki Y. [Effects of veterinary drugs on beta-hexosaminidase release from rat basophilic leukemia cells (RBL-2H3)]. Shokuhin Eiseigaku Zasshi. 2002;43:306-11 pubmed
    ..Based on the residual levels of these drugs and the frequencies of detection in actual food samples, it seems unlikely that these drugs have any immediate allergic effect in practice. ..
  69. Wagner B, Straw B, Fedorka Cray P, Dargatz D. Effect of antimicrobial dosage regimen on Salmonella and Escherichia coli isolates from feeder swine. Appl Environ Microbiol. 2008;74:1731-9 pubmed publisher
    ..different antimicrobial regimes (low-level continuous, pulse, and no antimicrobial) for two antimicrobials (chlortetracycline and tylosin) on the presence of Salmonella spp...
  70. Stanton T, Humphrey S. Isolation of tetracycline-resistant Megasphaera elsdenii strains with novel mosaic gene combinations of tet(O) and tet(W) from swine. Appl Environ Microbiol. 2003;69:3874-82 pubmed
    Anaerobic bacteria insensitive to chlortetracycline (64 to 256 microg/ml) were isolated from cecal contents and cecal tissues of swine fed or not fed chlortetracycline...
  71. Cardona Maya W, Cadavid A. [Acrosomal response of human sperm demonstrated with chlorotetracycline]. Ginecol Obstet Mex. 2004;72:659-60 pubmed
  72. Adachi J, Tate S, Miyake M, Harayama H. Effects of protein phosphatase inhibitor calyculin a on the postacrosomal protein serine/threonine phosphorylation state and acrosome reaction in boar spermatozoa incubated with a cAMP analog. J Reprod Dev. 2008;54:171-6 pubmed
    ..These results are consistent with our suggestion that postacrosomal serine/threonine-phosphorylated proteins are involved in suppression of the acrosome reaction in boar spermatozoa in vitro. ..
  73. Dairi T, Nakano T, Mizukami T, Aisaka K, Hasegawa M, Katsumata R. Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains. Biosci Biotechnol Biochem. 1995;59:1360-1 pubmed
    ..blot analysis, the DNA sequences homologous to the gene cluster responsible for biosynthesis of 6-demethyl-chlortetracycline in Streptomyces aureofaciens NRRL3203 were shown to be highly conserved in independent chlortetracycline- or ..
  74. Wu R, Alexander T, Li J, Munns K, Sharma R, McAllister T. Prevalence and diversity of class 1 integrons and resistance genes in antimicrobial-resistant Escherichia coli originating from beef cattle administered subtherapeutic antimicrobials. J Appl Microbiol. 2011;111:511-23 pubmed publisher
    ..in tetracycline-resistant Escherichia coli originating from beef cattle subtherapeutically administered chlortetracycline (A44), chlortetracycline and sulfamethazine (AS700), or no antimicrobials (control)...
  75. Cornick N. Tylosin and chlorotetracycline decrease the duration of fecal shedding of E. coli O157:H7 by swine. Vet Microbiol. 2010;143:417-9 pubmed publisher
    ..coli O157:H7. These results suggest that some antibiotics may alter the gastrointestinal tract flora in ways that create a less favorable environment for E. coli O157:H7 in swine. ..
  76. Stanton T, Humphrey S, Stoffregen W. Chlortetracycline-resistant intestinal bacteria in organically raised and feral Swine. Appl Environ Microbiol. 2011;77:7167-70 pubmed publisher
    Organically raised swine had high fecal populations of chlortetracycline (CTC)-resistant (growing at 64 ?g CTC/ml) Escherichia coli, Megasphaera elsdenii, and anaerobic bacteria...
  77. Lu L, Hume M, Pillai S. Autoinducer 2-like activity in poultry-associated enteric bacteria in response to subtherapeutic antibiotic exposure. Avian Dis. 2005;49:74-80 pubmed
    ..Understanding the relationships between AI-2 activity and microbial consortia characteristics could provide dues regarding the vulnerability of poultry chicks to enteric bacterial pathogen colonization. ..
  78. Hager D, Mayer P, Paulitz C, Tiebes J, Trauner D. Stereoselective total syntheses of herbicidin?C and aureonuclemycin through late-stage glycosylation. Angew Chem Int Ed Engl. 2012;51:6525-8 pubmed publisher
    ..The route integrates a stereoselective C-glycosylation with several reagent-controlled stereoselective transformations and a surprisingly facile and highly diastereoselective late-stage N-glycosylation. ..
  79. Bigdai E, Samoilov V. Components of the intracellular cAMP system supporting the olfactory reception of amyl alcohol. Neurosci Behav Physiol. 2003;33:89-94 pubmed
    ..Increases in intracellular cAMP levels resulted from activation of adenylate cyclase type III via odorant-induced stimulation of G protein linked to it. ..
  80. Khan M, Jung J. Ozonation of chlortetracycline in the aqueous phase: Degradation intermediates and pathway confirmed by NMR. Chemosphere. 2016;152:31-8 pubmed publisher
    b>Chlortetracycline (CTC) degradation mechanism in aqueous phase ozonation was evaluated for degradation mechanism and its correlation with the biodegradability and mineralization. CTC was removed within 8 and 4 min of ozonation at pH 2...
  81. Herman Antosiewicz A, Wegrzyn G. Regulation of copy number and stability of phage lambda derived pTC lambda 1 plasmid in the light of the dimer/multimer catastrophe hypothesis. FEMS Microbiol Lett. 1999;176:489-93 pubmed
    ..Results obtained with this plasmid in recombination proficient and deficient cells generally support the dimer/multimer catastrophe hypothesis, but also suggest some modification in the model. ..
  82. Hansen L, Aarestrup F, Sørensen S. Quantification of bioavailable chlortetracycline in pig feces using a bacterial whole-cell biosensor. Vet Microbiol. 2002;87:51-7 pubmed
    Bacterial whole-cell biosensors were used to measure the concentration of chlortetracycline (CTC) in the feces of pigs. In this study, the Escherichia coli biosensor used has a detection limit of 0.03 mg/kg CTC in pig feces...
  83. Schultz N, Capion N. Efficacy of salicylic acid in the treatment of digital dermatitis in dairy cattle. Vet J. 2013;198:518-23 pubmed publisher
    ..at day 0 during routine hoof trimming and were allocated into two groups, namely, a control group given chlortetracycline spray, and a treatment group given 10 g of salicylic acid powder applied topically within a bandage...
  84. Giannetti L, Longo F, Buiarelli F, Russo M, Neri B. Tetracycline residues in royal jelly and honey by liquid chromatography tandem mass spectrometry: validation study according to Commission Decision 2002/657/EC. Anal Bioanal Chem. 2010;398:1017-23 pubmed publisher
    ..robust liquid chromatography tandem mass spectrometry method for determining oxytetracycline, tetracycline, chlortetracycline and doxycycline in royal jelly and honey samples is presented...
  85. Stone J, Clay S, Spellman G. Tylosin and chlortetracycline effects during swine manure digestion: influence of sodium azide. Bioresour Technol. 2010;101:9515-20 pubmed publisher
    The antibiotics tylosin and chlortetracycline (CTC), which are commonly used in pig production, were studied to determine their effects on swine manure digestion in the presence and absence of biocide sodium azide...