vernonia

Summary

Summary: A plant genus of the family ASTERACEAE. Members contain germacrane and sesquiterpene LACTONES.

Webpages

  1. research note (screening of asteraceae (compositae) plant extracts for molluscicidal activity
    memorias.ioc.fiocruz.br/943/3709rn.html
  2. cw_rd_macro-moths
    www.neiu.edu/~cwinsect/s_macro-moths.html
  3. kansas prairie wildflowers
    spuds.agron.ksu.edu/wildflw.htm
  4. familia: asteraceae
    www.inbio.eas.ualberta.ca/bims/k03/p13/c045/o0144/f01362.htm
  5. a review of ethnobotanical research in palas valley, pakistan
    www.siu.edu/~ebl/leaflets/zafeer.htm
  6. providence health plans : oregon pebb employees
    www.providence.org/pebb/find_doctor.aspx
  7. asteraceae bercht. & j. presl: florabase: flora of western australia
    florabase.calm.wa.gov.au/browse/flora?f=345&level=f&id=345
  8. oregon gis data: by 7.5' quadrangle name
    libweb.uoregon.edu/map/map_section/quad_list.htm
  9. providence health plans : oregon pebb employees
    www.providence.org/healthplans/pebb/find_doctor.aspx
  10. oregon blue book: incorporated cities: arranged by county
    bluebook.state.or.us/local/cities/bycounty.htm

Publications

  1. Amelioration of carbon tetrachloride-induced hepatotoxicity by terpenoid extract from leaves of Vernonia amydgalina
    O O Babalola
    Department of Environmental Management and Toxicology, University of Agriculture, Abeokuta, Nigeria
    Afr J Med Med Sci 30:91-3
  2. In vitro cytotoxic elemanolides from Vernonia lasiopus
    J L Koul
    Planta Med 69:164-6
  3. Zaluzanin D: a fungistatic sesquiterpene from Vernonia arborea
    G N Krishna Kumari
    Centre for Natural Products, SPIC Science Foundation, SPIC House, 88 Mount Road, Chennai 600 032, India
    Fitoterapia 74:479-82
  4. Antimalarial activity of sesquiterpene lactones from Vernonia cinerea
    Aun Chea
    Laboratoire de Pharmacognosie, Faculté de Pharmacie, Marseille, France
    Chem Pharm Bull (Tokyo) 54:1437-9
  5. Sesquiterpene lactones with potent cytotoxic activities from Vernonia chinensis
    Xin Chen
    State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, P. R. China
    Planta Med 71:949-54
  6. In vitro screening of two Nigerian medicinal plants (Vernonia amygdalina and Annona senegalensis) for anthelmintic activity
    C B I Alawa
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Vet Parasitol 113:73-81
  7. Hepatoprotective and antioxidant activities of Vernonia amygdalina on acetaminophen-induced hepatic damage in mice
    B A Iwalokun
    Department of Biochemistry, Lagos State University, Apapa, Nigeria
    J Med Food 9:524-30
  8. Hypoglycaemic and antidiabetic activity of acetonic extract of Vernonia colorata leaves in normoglycaemic and alloxan-induced diabetic rats
    G Y Sy
    Laboratoire de Pharmacologie et de Physiologie, Faculté de Médecine et Pharmacie, Université Cheikh Anta Diop, BP 5005, Dakar, Sénégal
    J Ethnopharmacol 98:171-5
  9. Wound healing activity and systemic effects of Vernonia scorpioides extract in guinea pig
    S N Leite
    Núcleo de Investigações Químico Farmacêuticas, Curso de Farmácia, CCS, Universidade do Vale do Itajaí UNIVALI Rua Uruguai, 458 Itajaí, Santa Caterina, 88302 202, Brazil
    Fitoterapia 73:496-500
  10. A new highly oxygenated flavone from Veronia saligna
    Yue Huang
    Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650204, PR China
    Z Naturforsch [C] 58:347-50

Scientific Experts

  • Oluwatosin A Adaramoye
  • Cecilie Sogn Nergard
  • G Y Sy
  • S N Leite
  • Isabelle Billault
  • Ganiyu Oboh
  • Zeev Wiesman
  • D U Owu
  • Pamisha Pillay
  • María Campos
  • Yao-Haur Kuo
  • Ila Chaudhuri
  • Luiz C A Barbosa
  • G N Krishna Kumari
  • Qiao-li Liang
  • M A Taiwo
  • Ezekiel O Iwalewa
  • I Onyesom
  • Amanda Francine Asega
  • Xin Chen
  • Keshun Yu
  • S Grinberg
  • Jian-Min Yue
  • Malaya Gupta
  • U K Mazumder
  • Zha-Jun Zhan
  • Ernest B Izevbigie
  • L Manikandan
  • P K Haldar
  • S Bhattacharya
  • Jun Huo
  • Jesse B Nippert
  • Victor Barbastefano
  • Fernanda G Braga
  • Runzhi Li
  • Priti Maheshwari
  • E Shaubi
  • E Heldman
  • Jian Ding
  • C Linder
  • V Kolot
  • T Pagno
  • Olha Kos
  • Yi Cai
  • B A Iwalokun
  • P Erasto
  • Michael M Opata
  • Aun Chea
  • Russell B Williams
  • Aida Portillo
  • Giuseppina Cioffi
  • Guilian Tian
  • T R Seetharaman
  • Anthonia O Abosi
  • R Romanezi da Silveira
  • Yue Huang
  • S Roy
  • Alembert T Tchinda
  • J L Koul
  • C B I Alawa
  • Anna Belloni Fortina
  • Kamal A Saeed
  • O O Babalola
  • R J Deckelbaum
  • Shang Gao Liao
  • Li-Ping Lin
  • Bo Jun Xie
  • Shang-Gao Liao
  • Bo-Jun Xie
  • David Hildebrand
  • Sheng Ping Yang
  • Li Ping Lin
  • Tomoko Hatanaka
  • Jian Min Yue
  • Sheng-Ping Yang
  • Alba R M Souza-Brito
  • Bharti Songara
  • Shailesh Kumar
  • Elaine S Coimbra
  • Alan K Knapp
  • Anil Kumar
  • Anderson Luiz Ferreira
  • Elita Scio
  • Francis O Moreira
  • Maira Cola
  • Prachi Jain
  • Wagner Vilegas
  • Anderson Luiz-Ferreira
  • Daniel Rinaldo
  • Rodrigo L Fabri
  • Alba R M Souza Brito
  • Kamini Srivastava
  • Magnum de O Matos
  • Luis Poveda
  • David F Hildebrand
  • M R O Kreuger
  • L Z Blind
  • Renato Murillo
  • O A Magbagbeola
  • Charles T McCracken
  • Jin-sheng Wang
  • Robert Faure
  • Sotheara Hout
  • Riad Elias
  • Yi-lin Zhu
  • B U Efedede
  • D S Grierson
  • Nadine Azas
  • J A Alabi Sofunde
  • Christophe Long
  • Jian-bei Teng
  • Laurence Marcourt
  • M W Biavatti
  • A I Akinwande
  • A J Afolayan
  • Irmgard Merfort
  • T Oduala
  • Dan Liu
  • J A Alabi-Sofunde
  • Blanca Freixa

Detail Information

Webpages31 found, 30 most recent shown here

  1. research note (screening of asteraceae (compositae) plant extracts for molluscicidal activity
    memorias.ioc.fiocruz.br/943/3709rn.html
  2. cw_rd_macro-moths
    www.neiu.edu/~cwinsect/s_macro-moths.html
  3. kansas prairie wildflowers
    spuds.agron.ksu.edu/wildflw.htm
  4. familia: asteraceae
    www.inbio.eas.ualberta.ca/bims/k03/p13/c045/o0144/f01362.htm
  5. a review of ethnobotanical research in palas valley, pakistan
    www.siu.edu/~ebl/leaflets/zafeer.htm
  6. providence health plans : oregon pebb employees
    www.providence.org/pebb/find_doctor.aspx
  7. asteraceae bercht. & j. presl: florabase: flora of western australia
    florabase.calm.wa.gov.au/browse/flora?f=345&level=f&id=345
  8. oregon gis data: by 7.5' quadrangle name
    libweb.uoregon.edu/map/map_section/quad_list.htm
  9. providence health plans : oregon pebb employees
    www.providence.org/healthplans/pebb/find_doctor.aspx
  10. oregon blue book: incorporated cities: arranged by county
    bluebook.state.or.us/local/cities/bycounty.htm
  11. oregon parks and recreation department: state parks day use
    www.oregon.gov/OPRD/PARKS/dayuse.shtml
  12. germplasm use in arid lands industrial crops
    www.hort.purdue.edu/newcrop/proceedings1996/v3-292.html
  13. qualifiers for quagmires: landscape plants for wet sites
    www.ces.ncsu.edu/depts/hort/hil/hil-8646.html
  14. timothy helfer, j.d
    www.csustan.edu/cj/jjustice/index.html
  15. no title
    image.fs.uidaho.edu/vide/famly044.htm#Vernonia
  16. género: vernonia
    www.inbio.eas.ualberta.ca/bims/k03/p13/c045/o0144/f01362/g00 ...
  17. no title
    www.csdl.tamu.edu/FLORA/cgi/kartesz_ar_page?gen=Vernonia&spe ...
  18. no title
    www.csdl.tamu.edu/FLORA/cgi/kartesz_ar_page?gen=Vernonia&spe ...

Publications62

  1. Amelioration of carbon tetrachloride-induced hepatotoxicity by terpenoid extract from leaves of Vernonia amydgalina
    O O Babalola
    Department of Environmental Management and Toxicology, University of Agriculture, Abeokuta, Nigeria
    Afr J Med Med Sci 30:91-3
    Sesquiterpene lactone extract from the leaves of Vernonia amygdalina was tested for antihepatotoxic activity. Adult male rats were selected for the study...
  2. In vitro cytotoxic elemanolides from Vernonia lasiopus
    J L Koul
    Planta Med 69:164-6
    ..were isolated after chromatographic separation of the alcoholic extract of the dried aerial parts of the Vernonia lasiopus...
  3. Zaluzanin D: a fungistatic sesquiterpene from Vernonia arborea
    G N Krishna Kumari
    Centre for Natural Products, SPIC Science Foundation, SPIC House, 88 Mount Road, Chennai 600 032, India
    Fitoterapia 74:479-82
    Zaluzanin D, a sesquiterpene lactone has been isolated from the aerial parts of Vernonia arborea as a major constituent (0.04%). Antifungal activity of zaluzanin D has been studied against six plant-pathogenic fungi.
  4. Antimalarial activity of sesquiterpene lactones from Vernonia cinerea
    Aun Chea
    Laboratoire de Pharmacognosie, Faculté de Pharmacie, Marseille, France
    Chem Pharm Bull (Tokyo) 54:1437-9
    ..C and D as well as six known ones were isolated from the dichloromethane fraction of an aqueous extract from Vernonia cinerea. Their structures were elucidated by spectroscopic methods...
  5. Sesquiterpene lactones with potent cytotoxic activities from Vernonia chinensis
    Xin Chen
    State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, P. R. China
    Planta Med 71:949-54
    ..13-O-acetate (8), 8 alpha-tigloyloxyhirsutinolide 13-O-acetate ( 9) and vernolide-B (10) were isolated from Vernonia chinensis...
  6. In vitro screening of two Nigerian medicinal plants (Vernonia amygdalina and Annona senegalensis) for anthelmintic activity
    C B I Alawa
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Vet Parasitol 113:73-81
    b>Vernonia amygdalina and Annona senegalensis, two plants used by local/smallholder livestock farmers in Nigeria as anthelmintic were screened for in vitro anthelmintic activity using Haemonchus contortus eggs. The extract of V...
  7. Hepatoprotective and antioxidant activities of Vernonia amygdalina on acetaminophen-induced hepatic damage in mice
    B A Iwalokun
    Department of Biochemistry, Lagos State University, Apapa, Nigeria
    J Med Food 9:524-30
    b>Vernonia amygdalina Del. (Family Compositae) is used in Nigerian folk medicine as a tonic and remedy against constipation, fever, high blood pressure, and many infectious diseases...
  8. Hypoglycaemic and antidiabetic activity of acetonic extract of Vernonia colorata leaves in normoglycaemic and alloxan-induced diabetic rats
    G Y Sy
    Laboratoire de Pharmacologie et de Physiologie, Faculté de Médecine et Pharmacie, Université Cheikh Anta Diop, BP 5005, Dakar, Sénégal
    J Ethnopharmacol 98:171-5
    The aqueous extract of Vernonia colorata (Willd.) Drake (Composeae) leaves is used by African traditional medicine practitioners as a remedy for the treatment of diabetes...
  9. Wound healing activity and systemic effects of Vernonia scorpioides extract in guinea pig
    S N Leite
    Núcleo de Investigações Químico Farmacêuticas, Curso de Farmácia, CCS, Universidade do Vale do Itajaí UNIVALI Rua Uruguai, 458 Itajaí, Santa Caterina, 88302 202, Brazil
    Fitoterapia 73:496-500
    The ethanolic leaves extract of Vernonia scorpioides was investigated for its wound healing activity in guinea pigs...
  10. A new highly oxygenated flavone from Veronia saligna
    Yue Huang
    Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650204, PR China
    Z Naturforsch [C] 58:347-50
    ..1), together with other five known flavonoids were isolated from the tropical plant Vernonia saligna...
  11. Antifungal sesquiterpene from the root of Vernonanthura tweedieana
    Aida Portillo
    Unitat de Farmacologia i Farmacognòsia, Facultat de Farmàcia, Universitat de Barcelona, E-08028 Barcelona, Spain
    J Ethnopharmacol 97:49-52
    ..Minimal inhibitory concentrations (MIC) and minimal fungicidal concentrations (MFC) of 1 showed Trichophyton mentagrophytes as the most sensitive strain, with the same MIC and MFC values (4 microg/ml)...
  12. Two novel sesquiterpene lactones, cytotoxic vernolide-A and -B, from Vernonia cinerea
    Yao Haur Kuo
    National Research Institute of Chinese Medicine, Shih Pai, Taipei, Taiwan
    Chem Pharm Bull (Tokyo) 51:425-6
    Bioassay-directed fractionation of an ethanolic extract of stems of Vernonia cinerea has resulted in the isolation of two novel sesquiterpene lactones, vernolide-A and -B...
  13. Antiplasmodial hirsutinolides from Vernonia staehelinoides and their utilization towards a simplified pharmacophore
    Pamisha Pillay
    Biosciences, CSIR, RSA, P O Box 395, Pretoria 0001, South Africa
    Phytochemistry 68:1200-5
    The dichloromethane extract of the leaves of Vernonia staehelinoides Harv...
  14. Cytotoxic activity of the dichloromethane fraction from Vernonia scorpioides (Lam.) Pers. (Asteraceae) against Ehrlich's tumor cells in mice
    T Pagno
    Centro de Ciências da Saúde, Universidade do Vale do Itaja, Itaja, SC, Brasil
    Braz J Med Biol Res 39:1483-91
    b>Vernonia scorpioides has been widely used in Brazil to treat skin problems and chronic wounds, such as ulcers of the lower limbs and diabetic lesions...
  15. Cytotoxic sesquiterpene lactones from Vernonia pachyclada from the Madagascar rainforest
    Russell B Williams
    Department of Chemistry, M/C 0212, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061-0212, USA
    J Nat Prod 68:1371-4
    Bioassay-guided fractionation of the cytotoxic leaf extract of Vernonia pachyclada Baker led to the isolation of three new sesquiterpene lactones, designated glaucolides K-M (1-3)...
  16. Cytotoxic sesquiterpenoids from Vernonia bockiana
    Jun Huo
    Shanghai Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    J Asian Nat Prod Res 10:571-5
    ..A (5), hirsutolide (6), and beta-d-glucopyranosyl taraxinic ester (7), were isolated from the aerial part of Vernonia bockiana. Their structures were determined by spectroscopic analysis, especially 2D NMR...
  17. [Antidiabetic activity of the leaves of Vemonia colorata (Wilid.) Drake (Composees) in alloxan-induced diabetic rats]
    G Y Sy
    Laboratoire de Pharmacologie et de Physiologie, Faculté de Médecine et Pharmacie, Université Cheikh Anta Diop, Dakar, Sénégal
    Dakar Med 49:36-9
    ..This may indicate the ethnopharmacological basis of the use of V. colorata leaves in traditional medicine for treating diabetes...
  18. Vernonia polyanthes as a new source of antiulcer drugs
    Victor Barbastefano
    Departamento de Fisiologia e Biofísica, Instituto de Biologia, Universidade Estadual de Campinas UNICAMP, Cidade Universitária Zeferino Vaz, CP 6109, CEP13083 970, Campinas, SP, Brazil
    Fitoterapia 78:545-51
    Methanolic (VPME) and chloroformic (VPCL) extracts, obtained from the aerial parts of Vernonia polyanthes, were investigated for its antiulcerogenic properties...
  19. Evaluation of antipyretic potential of Vernonia cinerea extract in rats
    Malaya Gupta
    Department of Pharmaceutical Technology, Jadavpur University, Calcutta 700032, India
    Phytother Res 17:804-6
    The methanol extract of the whole plant of Vernonia cinerea (MEVC) was evaluated for its antipyretic potential on normal body temperature and yeast-induced pyrexia in rats...
  20. In vivo antimalarial activity of Vernonia amygdalina
    Anthonia O Abosi
    Department of Biological Sciences, Faculty of Science, PO Box 70050, University of Botswana, Gaborone, Botswana
    Br J Biomed Sci 60:89-91
    Extracts from the leaves and root bark of Vernonia amygdalina are assessed for antimalarial activity against drug-sensitive Plasmodium berghei in mice...
  21. Evaluation of anti-inflammatory activity of Vernonia cinerea Less. extract in rats
    U K Mazumder
    Department of Pharmaceutical Technology, Jadavpur University, Calcutta, India
    Phytomedicine 10:185-8
    The methanol extract of the whole plant of Vernonia cinerea Less. was evaluated for its anti-inflammatory activity in acute (carrageenin, histamine and serotonin induced rat paw edema) and a chronic model (cotton pouch induced granuloma)...
  22. Antibacterial activity of Vernonia cinerea
    Malaya Gupta
    Department of Pharmaceutical Technology, Jadavpur University, Calcutta 700 032, India
    Fitoterapia 74:148-50
    The benzene extract of Vernonia cinerea showed a broad spectrum of antibacterial activity.
  23. Nutritive value and haemolytic properties (in vitro) of the leaves of Vernonia amygdalina on human erythrocyte
    G Oboh
    Biochemistry Department, Federal University of Technology, P M B 704, Akure, Ondo State, Nigeria
    Nutr Health 18:151-60
    BACKGROUND: Vernonia amygdalina (Bitter leaf) is popularly consumed in many homes in Nigeria as a vegetable in soup preparation, while the infusion is used in folk medicine in the treatment of malaria fever...
  24. Stimulation of gastric acid secretion and intestinal motility by Vernonia amygdalina extract
    D U Owu
    Department of Physiology, College of Medical Sciences, University of Calabar, Calabar 540001, Nigeria
    Fitoterapia 79:97-100
    Aqueous extract of Vernonia amygdalina infused intragastrically at a dose of 10 mg/ml to rats induced a significant increase in acid output which was reduced by, ranitidine (5 mg/kg b.w.) or atropine (1.2 microMol/kg b.w.)...
  25. Effect of the crude extract of Vernonia polyanthes Less. on blood pressure and renal sodium excretion in unanesthetized rats
    R Romanezi da Silveira
    Disciplina de Medicina Interna, Laboratório Balanço Hidro-Salino, Núcleo de Medicina e Cirurgia Experimental, Departamento de Clinica Medica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil
    Phytomedicine 10:127-31
    This study evaluated the effect of oral crude Vernonia polyanthes Less. hydroalcoholic extract administration (CHE, 0.5 and 1.0 g/kg body wt., daily for 7 days) on arterial blood pressure and renal sodium excretion in conscious rats...
  26. [Mechanisms of action of acetonic and hexanic extracts of leaves of Vernonia colorata (Willd.) Drake (Composeae) on blod glucose regulation]
    G Y Sy
    Laoratoire de Pharmacologie, Faculté de Médecine, Pharmacie et d Odonto stomatologie, Université Cheikh Anta Diop, BP 5005, Dakar, Sénégal
    Dakar Med 51:42-6
    ..This study aimed to investigate the mechanism of action of acetonic and hexanic extracts of the leaves of Vernonia colorata on blood glucose regulation...
  27. Bioactive sesquiterpene lactones from the leaves of Vernonia amygdalina
    P Erasto
    Department of Botany, University of Fort Hare, Alice 5700, South Africa
    J Ethnopharmacol 106:117-20
    Phytochemical analysis of the leaves of Vernonia amygdalina yielded two known sesquiterpene lactones: vernolide and vernodalol. The two compounds were tested by agar dilution method against 10 bacteria strains and 5 fungi species...
  28. Quantitative deuterium isotopic profiling at natural abundance indicates mechanistic differences for delta 12-epoxidase and delta 12-desaturase in Vernonia galamensis
    Isabelle Billault
    Groupe de Fractionnement Isotopique de Métabolismes, Laboratoire d Analyse Isotopique et Electrochimique de Métabolismes, CNRS UMR6006, Université de Nantes, BP 99208, F 44322 Nantes, France
    J Biol Chem 280:17645-51
    ..Vernolic acid, a major component of the seed oil of Vernonia galamensis, contains both an epoxide and a desaturation...
  29. Sesquiterpenoids from Vernonia cinerea
    Xin Chen
    State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 201203, P.R. China
    Nat Prod Res 20:125-9
    ..vernocinolide A (1), as well as ten known ones (2-11), were isolated from the ethyl acetate soluble fraction of Vernonia cinerea. The structure of vernocinolide A (1) was elucidated by spectroscopic methods...
  30. Sesquiterpenoids from Vernonia cinerea
    Xin Chen
    State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai, P.R. China 201203
    Nat Prod Res 20:31-5
    ..The structure of vernocinolide A was elucidated by spectroscopic methods. Among the known sesquiterpenoids, nine of them were isolated from this plant for the first time...
  31. Ent-kaurane glycosides and sesquiterpene lactones of the hirsutinolide type from Vernonia triflosculosa
    Olha Kos
    Institute of Pharmaceutical Sciences, Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University of Freiburg, Stefan-Meier-Street 19, 79104 Freiburg, Germany
    Phytochemistry 67:62-9
    Investigation of the aerial parts of Vernonia triflosculosa afforded three hirsutinolides of which 8alpha-(4alpha-hydroxymethacryloyloxy)-10alpha-hydroxy-1,13-dimethoxy-hirsutinolide is new, three ent-kaurane diterpenes, among which the ..
  32. Antileishmanial and antifungal activity of plants used in traditional medicine in Brazil
    Fernanda G Braga
    Departamento de Parasitologia, Microbiologia e Imunologia, ICB, Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil
    J Ethnopharmacol 111:396-402
    ..Among the 20 tested methanolic extracts, those of Vernonia polyanthes was the most active against L...
  33. A novel natural inhibitor of extracellular signal-regulated kinases and human breast cancer cell growth
    Ernest B Izevbigie
    The Molecular Genetics and Molecular and Cellular Signaling Laboratory, Department of Biology, and National Institutes of Health Center for Environmental Health, Jackson State University, Mississippi 39217, USA
    Exp Biol Med (Maywood) 229:163-9
    Water-soluble extracts of edible Vernonia amygdalina leaves were recently reported as potent inhibitors of cultured MCF-7 cells. The mechanism by which V. amygdalina inhibits MCF-7 cell growth has not been previously studied...
  34. Aqueous Vernomia amygdalina extracts alter MCF-7 cell membrane permeability and efflux
    Michael M Opata
    The Laboratory of Phytoceuticals, and Cancer Prevention and Therapies Department of Biology, Jackson State University, 1400 J. R. Lynch Street, P.O Box 18540, Jackson, MS 39217, USA
    Int J Environ Res Public Health 3:174-9
    ..05). The amount of [3H]thymidine released into the medium was 1.7, 7.4, and 11.0 % for 0, 30, and 100 mug/ml VA respectively. Thus suggesting the membranes in VA-treated cells were compromised in a concentration-dependent fashion...
  35. Pro- and antioxidant effects and cytoprotective potentials of nine edible vegetables in southwest Nigeria
    E O Iwalewa
    Department of Pharmacology, Faculty of Pharmacy, Obafemi Awolowo University, Ile Ife, Nigeria
    J Med Food 8:539-44
    ..Crassocephalum rubens showed the highest antioxidant activity (56.5%), Solanum americanum and Vernonia amygdalina exhibited moderate antioxidant activity (26.0-37.5% and 14.8-36...
  36. [Pharmacognostical identification of Vernonia patula (Dry) Merr]
    Yi Cai
    Guangxi College of Traditional Chinese Medicine, Nanning 530001, China
    Zhong Yao Cai 29:116-8
    OBJECTIVE: To identify Vernonia patula (Dry) Merry. METHODS: Characteristic study, microscopic identification and UV spectrometry method were carried out...
  37. New compounds from an extract of Vernonia colorata leaves with anti-inflammatory activity
    Giuseppina Cioffi
    Dipartimento di Scienze Farmaceutiche, Università di Salerno, Via Ponte Don Melillo, 84084 Fisciano (SA, Italy
    J Nat Prod 67:389-94
    Bioassay-directed fractionation of an anti-inflammatory CHCl(3)-MeOH (9:1) extract of leaves of Vernonia colorata, using a carrageenan-induced rat paw model, led to the isolation of six new compounds (1-6)...
  38. Lipid-lowering effects of methanolic extract of Vernonia amygdalina leaves in rats fed on high cholesterol diet
    Oluwatosin A Adaramoye
    Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria
    Vasc Health Risk Manag 4:235-41
    We investigated the lipid-lowering effects of methanolic extract of Vernonia amygdalina (VA) leaves in rats fed an high cholesterol diet, and compared with a standard hypolipidemic drug, Questran (Qu)...
  39. Analgesic, antipyretic, anti-inflammatory effects of methanol, chloroform and ether extracts of Vernonia cinerea less leaf
    E O Iwalewa
    Department of Pharmacology, Obafemi Awolowo University, Ile Ife, Nigeria
    J Ethnopharmacol 86:229-34
    The chloroform, methanolic and ether extracts of Vernonia cinerea (Asteraceae; Less) leaf (100, 200 and 400mg/kg intraperitoneally) were tested in: acetic acid-induced writhing in mice, carrageenin-induced oedema and brewer's yeast-..
  40. Novel cationic amphiphilic derivatives from vernonia oil: synthesis and self-aggregation into bilayer vesicles, nanoparticles, and DNA complexants
    S Grinberg
    The Institutes for Applied Research, and the Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Langmuir 21:7638-45
    Self-assembling nanostructures were prepared from novel cationic amphiphilic compounds synthesized from vernonia oil, a natural epoxydized triglyceride...
  41. Contact dermatitis from Vernonia noveboracensis
    Anna Belloni Fortina
    Department of Dermatology, University of Padua, Padua, Italy
    Contact Dermatitis 46:357-8
  42. Structures and structure-activity relationships of three mitogenic and complement fixing pectic arabinogalactans from the malian antiulcer plants Cochlospermum tinctorium A. Rich and Vernonia kotschyana Sch. Bip. ex Walp
    Cecilie Sogn Nergard
    Department of Pharmacognosy, School of Pharmacy, University of Oslo, P.O. Box 1068, Blindern, 0316 Oslo, Norway
    Biomacromolecules 7:71-9
    Structures of three pectic arabinogalactans, one from Vernonia kotschyana (Vk2a) and two from Cochlospermum tinctorium (Ct50A1 and Ct50A2), and their complement fixation and induction of B cell proliferation in vitro were compared...
  43. Characterization of copolymer hydroxybutyrate/hydroxyvalerate from saponified vernonia, soybean, and "spent" frying oils
    Kamal A Saeed
    Department of Chemistry, Howard University, Washington, DC 20059, USA
    J AOAC Int 85:917-24
    ..were biosynthesized by Ralstonia eutropha (formerly known as Alcaligenes eutrophus) by using saponified soybean, vernonia, and "spent" frying oils...
  44. Separation of flavonoids from the seeds of Vernonia anthelmintica Willd by high-speed counter-current chromatography
    Guilian Tian
    Beijing Institute of New Technology Application, Beijing 100035, China
    J Chromatogr A 1049:219-22
    ..2',3,4,4'-tetrahydroxychalcone, 5,6,7,4'-tetrahydroxyflavone and butin, were separated from the seeds of Vernonia anthelmintica Willd by high-speed counter-current chromatography using a two-step operation...
  45. Structural and immunological studies of a pectin and a pectic arabinogalactan from Vernonia kotschyana Sch. Bip. ex Walp. (Asteraceae)
    Cecilie Sogn Nergard
    Department of Pharmacognosy, School of Pharmacy, University of Oslo, P O Box 1068, Blindern, 0316 Oslo, Norway
    Carbohydr Res 340:115-30
    ..15 x 10(6)Da, respectively, were isolated from the dried powdered roots of Vernonia kotschyana Sch. Bip. ex Walp...
  46. Linking water uptake with rooting patterns in grassland species
    Jesse B Nippert
    Division of Biology, Kansas State University, Manhattan, KS 66506, USA
    Oecologia 153:261-72
    ..Thus, our results suggest that variation in precipitation history and landscape positions are greater determinants of water-use patterns than would be expected based on absolute rooting depth...
  47. Isolation, partial characterisation and immunomodulating activities of polysaccharides from Vernonia kotschyana Sch. Bip. ex Walp
    Cecilie Sogn Nergard
    Department of Pharmacognosy, School of Pharmacy, PO Box 1068, Blindern, 0316 Oslo, Norway
    J Ethnopharmacol 91:141-52
    The roots from Vernonia kotschyana Sch. Bip. ex Walp. (Baccharoides adoensis var. kotschyana (Sch. Bip. ex Walp.) M.A. Isawumi, G.El-Ghazaly & B...
  48. Fructan metabolising enzymes in rhizophores of Vernonia herbacea upon excision of aerial organs
    Amanda Francine Asega
    Seção de Fisiologia e Bioquímica, Instituto de Botânica, Caixa Postal 4005, CEP 01061-970, Sao Paulo, Brazil
    Plant Physiol Biochem 42:313-9
    The activities of fructan metabolising enzymes and fructan contents are reported for rhizophores of Vernonia herbacea (Vell.) Rusby induced to sprouting by shoot excision...
  49. Alkaloid production in Vernonia cinerea: Callus, cell suspension and root cultures
    Priti Maheshwari
    School of Biotechnology, Devi Ahilya University, Indore, India
    Biotechnol J 2:1026-32
    Fast-growing callus, cell suspension and root cultures of Vernonia cinerea, a medicinal plant, were analyzed for the presence of alkaloids...
  50. Cloning and functional analysis of two type 1 diacylglycerol acyltransferases from Vernonia galamensis
    Keshun Yu
    Department of Plant and Soil Science, University of Kentucky, 1405 Veterans Drive, Lexington, KY 40546 0091, USA
    Phytochemistry 69:1119-27
    b>Vernonia galamensis accumulates vernolic acid (cis-12-epoxyoctadeca-cis-9-enoic acid) as the major fatty acid in its seed oil. Such epoxy fatty acids are useful in a number of industrial applications...
  51. [Studies on the constituents from the herb of Vernonia patula]
    Qiao li Liang
    Nanjing Normal University, Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu, China
    Zhongguo Zhong Yao Za Zhi 28:235-7
    OBJECTIVE: To isolate and elucidate the chemical constituents of the whole plant of Vernonia patula, and to provide samples for biological activity screening...
  52. Novel acylkaempferol glycoside from the endemic species, Vernonia travancorica Hook. f
    T R Seetharaman
    Department of Chemistry, Kanchi Mamunivar Centre for Post-Graduate Studies, Pondicherry, India
    J Asian Nat Prod Res 6:295-9
    b>Vernonia travancorica Hook. f. is a taxon, endemic to the evergreen forests of Western Ghats (above 1000 m), India...
  53. Stigmastane derivatives and isovaleryl sucrose esters from Vernonia guineensis (Asteraceae)
    Alembert T Tchinda
    Department of Chemistry, University of Dschang, Box 67, Dschang, Cameroon
    Phytochemistry 63:841-6
    ..alpha-D-glucopyranoside (4), have been isolated from the stem bark of Vernonia guineensis. The structures of the new compounds were determined on the basis of spectroscopic evidence.
  54. Quantitative analysis of nitrate and nitrite contents in vegetables commonly consumed in Delta State, Nigeria
    I Onyesom
    Department of Biochemistry, PO Box 144, Delta State University, Abraka, Nigeria
    Br J Nutr 96:902-5
    ..The nitrate and nitrite contents in green vegetable (Amaranthus spp.), bitter leaf (Vernonia amygdalina), pumpkin (Telfaria occidentalis) and water leaf (Talinum triangulare) grown in different localities ..
  55. Novel cationic vesicle platform derived from vernonia oil for efficient delivery of DNA through plant cuticle membranes
    Zeev Wiesman
    Phyto Lipid Biotechnology Laboratory, Department of Biotechnology Engineering, Faculty of Engineering, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    J Biotechnol 130:85-94
    Novel cationic amphiphilic compounds were prepared from vernonia oil, a natural epoxidized triglyceride, and studied with respect to vesicle formation, encapsulation of biomaterials such as DNA, and their physical stability and transport ..
  56. Protective effects of extracts of Vernonia amygdalina, Hibiscus sabdariffa and vitamin C against radiation-induced liver damage in rats
    Oluwatosin Adaramoye
    Department of Biochemistry, University of Ibadan, Ibadan, Nigeria
    J Radiat Res (Tokyo) 49:123-31
    The radioprotective efficacy of methanolic extracts of leaves of Vernonia amygdalina (VA) and Hibiscus sabdariffa (HS), and vitamin C (VIT C) against gamma radiation (4 Gy) induced liver damage was studied in male Wistar albino rats...
  57. Diacylglycerol acyltransferases from Vernonia and Stokesia prefer substrates with vernolic acid
    Keshun Yu
    Department of Plant and Soil Sciences, University of Kentucky, Lexington, Kentucky 40546, USA
    Lipids 41:557-66
    ..preferences of acyl CoA:diacylglycerol acyltransferases (DGAT) of two natural high accumulators of vernolic acid, Vernonia galamensis and Stokesia laevis, as compared with a common oilseed crop soybean...
  58. Synthesis of novel cationic bolaamphiphiles from vernonia oil and their aggregated structures
    S Grinberg
    Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva, Israel
    Chem Phys Lipids 153:85-97
    ..These bolaamphiphiles were derived from vernonia oil, whose main constituent is vernolic acid, a fatty acid with a unique combination of epoxy, carboxy and ..
  59. Cloning, characterization and functional analysis of a 1-FEH cDNA from Vernonia herbacea (Vell.) Rusby
    Amanda Francine Asega
    Seção de Fisiologia e Bioquímica de Plantas, Instituto de Botânica, CP 3005, 01061 970, São Paulo, SP, Brazil
    Plant Cell Physiol 49:1185-95
    Variations in the inulin contents have been detected in rhizophores of Vernonia herbacea during the phenological cycle...
  60. Properties of a virus isolated from Vernonia amygdalina Del. in Lagos, Nigeria
    M A Taiwo
    Department of Botany and Microbiology, University of Lagos, Akoka, Lagos, Nigeria
    Acta Virol 48:257-62
    A previously uncharacterized virus tentatively named Vernonia green vein-banding virus (VGVBV) was isolated from Vernonia amygdalina Del. ("bitterleaf") from Lagos, Nigeria...