rhizome

Summary

Summary: Root-like underground horizontal stem of plants that produces shoots above and roots below. Distinguished from true roots which don't have buds and nodes. Similar to true roots in being underground and thickened by storage deposits.

Top Publications

  1. Han P, Han T, Peng W, Wang X. Antidepressant-like effects of essential oil and asarone, a major essential oil component from the rhizome of Acorus tatarinowii. Pharm Biol. 2013;51:589-94 pubmed publisher
    ..However, there is no report on antidepressant-like effects of the essential oil (EO) and its major components on animals under standardized experimental procedures...
  2. Diene S, Merhej V, Henry M, El Filali A, Roux V, Robert C, et al. The rhizome of the multidrug-resistant Enterobacter aerogenes genome reveals how new "killer bugs" are created because of a sympatric lifestyle. Mol Biol Evol. 2013;30:369-83 pubmed publisher
    ..it is a chimera of transposons and integrative conjugative elements from various bacterial origins, resembling a rhizome. Moreover, we demonstrate biologically that a G53S mutation in the pmrA gene results in colistin resistance. E...
  3. Annadurai R, Neethiraj R, Jayakumar V, Damodaran A, Rao S, Katta M, et al. De Novo transcriptome assembly (NGS) of Curcuma longa L. rhizome reveals novel transcripts related to anticancer and antimalarial terpenoids. PLoS ONE. 2013;8:e56217 pubmed publisher
    ..We sequenced the transcriptome of the rhizome of the 3 varieties of Curcuma longa L...
  4. Li X, Cui X, Wang J, Yang J, Sun X, Li X, et al. Rhizome of Anemarrhena asphodeloides counteracts diabetic ophthalmopathy progression in streptozotocin-induced diabetic rats. Phytother Res. 2013;27:1243-50 pubmed publisher
    ..Here, we investigated the effect of 60% ethanol extract of the rhizome of Anemarrhenae asphodeloides (ERA), which is commonly used in Chinese medicine formulae in treating diabetes, on ..
  5. Xian Y, Lin Z, Xu X, Su Z, Chen J, Lai X, et al. Effect of Rhizoma Polygonati on 12-O-tetradecanoylphorbol-acetate-induced ear edema in mice. J Ethnopharmacol. 2012;142:851-6 pubmed publisher
    ..Rhizoma Polygonati is originated from the dried rhizomes of Polygonatum sibircum Red. It has long been used in traditional Chinese medicine for the treatment of inflammatory disorders...
  6. Le T, Jeong J, Kim D. Clionosterol and ethyl cholestan-22-enol isolated from the rhizome of Polygala tenuifolia inhibit phosphatidylinositol 3-kinase/Akt pathway. Biol Pharm Bull. 2012;35:1379-83 pubmed
    Phosphatidylinositol 3-kinase (PI3K)/Akt inhibitors were isolated from the rhizome of Polygala tenuifolia WILLD (PT, Polygalaceae), which has been used in traditional Chinese medicine for inflammation, dementia, amnesia, neurasthenia and ..
  7. Yi L, Xu Q, Li Y, Yang L, Kong L. Antidepressant-like synergism of extracts from magnolia bark and ginger rhizome alone and in combination in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2009;33:616-24 pubmed publisher
    Magnolia bark and ginger rhizome is a drug pair in many prescriptions for treatment of mental disorders in traditional Chinese medicine (TCM)...
  8. Mishra K, Padwad Y, Dutta A, Ganju L, Sairam M, Banerjee P, et al. Aqueous extract of Rhodiola imbricata rhizome inhibits proliferation of an erythroleukemic cell line K-562 by inducing apoptosis and cell cycle arrest at G2/M phase. Immunobiology. 2008;213:125-31 pubmed publisher
    ..These observations suggest that aqueous extract of R. imbricata rhizome has very potent anti-cancer activities, which might be useful in leukemia cancer treatment.
  9. Sabulal B, Dan M, J A, Kurup R, Pradeep N, Valsamma R, et al. Caryophyllene-rich rhizome oil of Zingiber nimmonii from South India: Chemical characterization and antimicrobial activity. Phytochemistry. 2006;67:2469-73 pubmed
    ..Sixty-five constituents accounting for 97.5% of the oil were identified. Z. nimmonii rhizome oil is a unique caryophyllene-rich natural source with isomeric caryophyllenes, beta-caryophyllene (42...
  10. Winkel A, Colmer T, Pedersen O. Leaf gas films of Spartina anglica enhance rhizome and root oxygen during tidal submergence. Plant Cell Environ. 2011;34:2083-92 pubmed publisher
    ..Plants had leaf gas films intact or removed. Rhizome pO(2) dropped significantly during complete submergence and most severely during night...

Detail Information

Publications84

  1. Han P, Han T, Peng W, Wang X. Antidepressant-like effects of essential oil and asarone, a major essential oil component from the rhizome of Acorus tatarinowii. Pharm Biol. 2013;51:589-94 pubmed publisher
    ..However, there is no report on antidepressant-like effects of the essential oil (EO) and its major components on animals under standardized experimental procedures...
  2. Diene S, Merhej V, Henry M, El Filali A, Roux V, Robert C, et al. The rhizome of the multidrug-resistant Enterobacter aerogenes genome reveals how new "killer bugs" are created because of a sympatric lifestyle. Mol Biol Evol. 2013;30:369-83 pubmed publisher
    ..it is a chimera of transposons and integrative conjugative elements from various bacterial origins, resembling a rhizome. Moreover, we demonstrate biologically that a G53S mutation in the pmrA gene results in colistin resistance. E...
  3. Annadurai R, Neethiraj R, Jayakumar V, Damodaran A, Rao S, Katta M, et al. De Novo transcriptome assembly (NGS) of Curcuma longa L. rhizome reveals novel transcripts related to anticancer and antimalarial terpenoids. PLoS ONE. 2013;8:e56217 pubmed publisher
    ..We sequenced the transcriptome of the rhizome of the 3 varieties of Curcuma longa L...
  4. Li X, Cui X, Wang J, Yang J, Sun X, Li X, et al. Rhizome of Anemarrhena asphodeloides counteracts diabetic ophthalmopathy progression in streptozotocin-induced diabetic rats. Phytother Res. 2013;27:1243-50 pubmed publisher
    ..Here, we investigated the effect of 60% ethanol extract of the rhizome of Anemarrhenae asphodeloides (ERA), which is commonly used in Chinese medicine formulae in treating diabetes, on ..
  5. Xian Y, Lin Z, Xu X, Su Z, Chen J, Lai X, et al. Effect of Rhizoma Polygonati on 12-O-tetradecanoylphorbol-acetate-induced ear edema in mice. J Ethnopharmacol. 2012;142:851-6 pubmed publisher
    ..Rhizoma Polygonati is originated from the dried rhizomes of Polygonatum sibircum Red. It has long been used in traditional Chinese medicine for the treatment of inflammatory disorders...
  6. Le T, Jeong J, Kim D. Clionosterol and ethyl cholestan-22-enol isolated from the rhizome of Polygala tenuifolia inhibit phosphatidylinositol 3-kinase/Akt pathway. Biol Pharm Bull. 2012;35:1379-83 pubmed
    Phosphatidylinositol 3-kinase (PI3K)/Akt inhibitors were isolated from the rhizome of Polygala tenuifolia WILLD (PT, Polygalaceae), which has been used in traditional Chinese medicine for inflammation, dementia, amnesia, neurasthenia and ..
  7. Yi L, Xu Q, Li Y, Yang L, Kong L. Antidepressant-like synergism of extracts from magnolia bark and ginger rhizome alone and in combination in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2009;33:616-24 pubmed publisher
    Magnolia bark and ginger rhizome is a drug pair in many prescriptions for treatment of mental disorders in traditional Chinese medicine (TCM)...
  8. Mishra K, Padwad Y, Dutta A, Ganju L, Sairam M, Banerjee P, et al. Aqueous extract of Rhodiola imbricata rhizome inhibits proliferation of an erythroleukemic cell line K-562 by inducing apoptosis and cell cycle arrest at G2/M phase. Immunobiology. 2008;213:125-31 pubmed publisher
    ..These observations suggest that aqueous extract of R. imbricata rhizome has very potent anti-cancer activities, which might be useful in leukemia cancer treatment.
  9. Sabulal B, Dan M, J A, Kurup R, Pradeep N, Valsamma R, et al. Caryophyllene-rich rhizome oil of Zingiber nimmonii from South India: Chemical characterization and antimicrobial activity. Phytochemistry. 2006;67:2469-73 pubmed
    ..Sixty-five constituents accounting for 97.5% of the oil were identified. Z. nimmonii rhizome oil is a unique caryophyllene-rich natural source with isomeric caryophyllenes, beta-caryophyllene (42...
  10. Winkel A, Colmer T, Pedersen O. Leaf gas films of Spartina anglica enhance rhizome and root oxygen during tidal submergence. Plant Cell Environ. 2011;34:2083-92 pubmed publisher
    ..Plants had leaf gas films intact or removed. Rhizome pO(2) dropped significantly during complete submergence and most severely during night...
  11. Yan Ye -, Chou G, Hui Wang -, Chu J, Fong W, Yu Z. Effects of sesquiterpenes isolated from largehead atractylodes rhizome on growth, migration, and differentiation of B16 melanoma cells. Integr Cancer Ther. 2011;10:92-100 pubmed publisher
    The aims of this study were to isolate sesquiterpene compounds from the largehead atractylodes rhizome (LAR) and to investigate their effects on B16 cancer cells...
  12. Jantan I, Raweh S, Sirat H, Jamil S, Mohd Yasin Y, Jalil J, et al. Inhibitory effect of compounds from Zingiberaceae species on human platelet aggregation. Phytomedicine. 2008;15:306-9 pubmed
    ..Curcumin was the most effective antiplatelet compound as it inhibited AA-, collagen- and ADP-induced platelet aggregation with IC(50) values of 37.5, 60.9 and 45.7 microM, respectively...
  13. Mishra K, Padwad Y, Jain M, Karan D, Ganju L, Sawhney R. Aqueous extract of Rhodiola imbricata rhizome stimulates proinflammatory mediators via phosphorylated IkappaB and transcription factor nuclear factor-kappaB. Immunopharmacol Immunotoxicol. 2006;28:201-12 pubmed
    ..We have evaluated the immunomodulatory activity of aqueous extract of Rhodiola rhizome in human peripheral blood mononuclear cells (PBMCs) and mouse macrophage cell line RAW 264.7...
  14. Al Adhroey A, Nor Z, Al Mekhlafi H, Mahmud R. Median lethal dose, antimalarial activity, phytochemical screening and radical scavenging of methanolic Languas galanga rhizome extract. Molecules. 2010;15:8366-76 pubmed publisher
    ..The extract also exhibited a moderate capacity to scavenge the free radicals. The rhizome extract of Languas galanga thus possesses antimalarial activity, which explains the rational usage of this plant ..
  15. Wang J, Ji L, Liu H, Wang Z. Study of the hepatotoxicity induced by Dioscorea bulbifera L. rhizome in mice. Biosci Trends. 2010;4:79-85 pubmed
    ..bulbifera rhizome. On this basis, to study the hepatotoxicity induced by the toxic ingredients, mice were treated with 0...
  16. Bai W, Xun F, Li Y, Zhang W, Li L. Rhizome severing increases root lifespan of Leymus chinensis in a typical steppe of Inner Mongolia. PLoS ONE. 2010;5:e12125 pubmed publisher
    ..We investigated the effects of rhizome severing on overall root lifespan of Leymus chinensis, a clonal, dominant grass species in the temperate steppe ..
  17. Yusoff M, Ibrahim H, Hamid N. Chemical characterization and antimicrobial activity of rhizome essential oils of very closely allied Zingiberaceae species endemic to Borneo: Alpinia ligulata K. Schum. and Alpinia nieuwenhuizii Val. Chem Biodivers. 2011;8:916-23 pubmed publisher
    ..A. ligulata and A. nieuwenhuizii, were investigated here for their rhizome essential oil. The oil compositions and antimicrobial activities were compared with those of A...
  18. Chen X, Lu J, He W, Chi H, Yamashita K, Manabe M, et al. Antiperoxidation activity of triterpenoids from rhizome of Anemone raddeana. Fitoterapia. 2009;80:105-11 pubmed publisher
    ..E (1), hederasaponin B (2), raddeanoside 20 (3) and raddeanoside 21 (4) were isolated from ethanol extracts of rhizome of Anemone raddeana Regel...
  19. Huang B, He J, Ban X, Zeng H, YAO X, Wang Y. Antioxidant activity of bovine and porcine meat treated with extracts from edible lotus (Nelumbo nucifera) rhizome knot and leaf. Meat Sci. 2011;87:46-53 pubmed publisher
    Lotus (Nelumbo nucifera) is an extensively cultivated vegetable in eastern Asia, particularly in China. Both lotus rhizome knot (LRK) and lotus leaf (LL) are waste products of the lotus industry...
  20. Chang N, Wu C, Wang S, Pei R, Lin C. Alpinia pricei Hayata rhizome extracts have suppressive and preventive potencies against hypercholesterolemia. Food Chem Toxicol. 2010;48:2350-6 pubmed publisher
    ..These results suggest that APE has both suppressive and preventive potencies against hypercholesterolemia and has the potency to protect against lipid peroxidation...
  21. Lantz R, Chen G, Sarihan M, Solyom A, Jolad S, Timmermann B. The effect of extracts from ginger rhizome on inflammatory mediator production. Phytomedicine. 2007;14:123-8 pubmed
    ..We have used an in vitro test system to test the anti-inflammatory activity of compounds isolated from ginger rhizome. U937 cells were differentiated and exposed to lipopolysaccharide (LPS) from Escherichia coli (1 microg/ml) in ..
  22. Gupta S, Pandotra P, Gupta A, Dhar J, Sharma G, Ram G, et al. Volatile (As and Hg) and non-volatile (Pb and Cd) toxic heavy metals analysis in rhizome of Zingiber officinale collected from different locations of North Western Himalayas by Atomic Absorption Spectroscopy. Food Chem Toxicol. 2010;48:2966-71 pubmed publisher
    Ginger is an important ingredient of spice and herbals. The monitoring of toxic heavy metals in the rhizome of ginger is important for protecting public health against the hazards of metal toxicity...
  23. Policegoudra R, Rehna K, Rao L, Aradhya S. Antimicrobial, antioxidant, cytotoxicity and platelet aggregation inhibitory activity of a novel molecule isolated and characterized from mango ginger (Curcuma amada Roxb.) rhizome. J Biosci. 2010;35:231-40 pubmed
    Mango ginger (Curcuma amada Roxb.) rhizome is used in the manufacture of pickles and other food preparations due to its unique raw mango flavour...
  24. He R, Kim M, Nelson W, Balbuena T, Kim R, Kramer R, et al. Next-generation sequencing-based transcriptomic and proteomic analysis of the common reed, Phragmites australis (Poaceae), reveals genes involved in invasiveness and rhizome specificity. Am J Bot. 2012;99:232-47 pubmed publisher
    ..Characterization of the rhizome transcriptome and proteome is needed to identify candidate genes and proteins involved in rhizome growth, ..
  25. Shin M, Kim S, Kim Y, Kim S, Ko I, Kim Y, et al. Aqueous extract of Anemarrhena rhizome increases cell proliferation and neuropeptide Y expression in the hippocampal dentate gyrus on streptozotocin-induced diabetic rats. Fitoterapia. 2008;79:323-7 pubmed publisher
    In this study, the effects of the aqueous extract of Anemarrhena rhizome on cell proliferation and neuropeptide Y expression in the dentate gyrus of streptozotocin-induced diabetic rats were investigated via immunohistochemistry for 5-..
  26. Baliga M, Haniadka R, Pereira M, Thilakchand K, Rao S, Arora R. Radioprotective effects of Zingiber officinale Roscoe (ginger): past, present and future. Food Funct. 2012;3:714-23 pubmed publisher
    ..The hydroalcoholic extract of ginger rhizome when administered either through intraperitoneal or oral route was effective in protecting against gamma ..
  27. Hu F, Wang D, Zhao X, Zhang T, Sun H, Zhu L, et al. Identification of rhizome-specific genes by genome-wide differential expression analysis in Oryza longistaminata. BMC Plant Biol. 2011;11:18 pubmed publisher
    ..wild rice with strong rhizomes, has been used as the model species for genetic and molecular dissection of rhizome development and in breeding efforts to transfer rhizome-related traits into annual rice species...
  28. Haldar P, Kar B, Bala A, Bhattacharya S, Mazumder U. Antitumor activity of Sansevieria roxburghiana rhizome against Ehrlich ascites carcinoma in mice. Pharm Biol. 2010;48:1337-43 pubmed publisher
    ..Sansevieria roxburghiana Schult. & Schult. f. (Agavaceae) is a herbaceous perennial plant traditionally used for coughs, rheumatism; as an expectorant, febrifuge, purgative, and tonic...
  29. Kim J, Jung H, Choi J, Lee N. Identification of anti-inflammatory target genes of Rhizoma coptidis extract in lipopolysaccharide-stimulated RAW264.7 murine macrophage-like cells. J Ethnopharmacol. 2010;130:354-62 pubmed publisher
    ..The aim of this study was to identify the anti-inflammatory target genes of Rhizoma coptidis extract (CEX) in lipopolysaccharide (LPS)-stimulated RAW264.7 murine macrophage-like cells...
  30. Liu B, Liu F, Chen C, Gao H. Supercritical carbon dioxide extraction of ethyl p-methoxycinnamate from Kaempferia galanga L. rhizome and its apoptotic induction in human HepG2 cells. Nat Prod Res. 2010;24:1927-32 pubmed publisher
    In this study, supercritical carbon dioxide extraction of ethyl p-methoxycinnamate from Kaempferia galanga L. rhizome and its apoptotic induction in human HepG2 cells are reported for the first time...
  31. Kong W, Zhao Y, Xiao X, Wang J, Li H, Li Z, et al. Spectrum-effect relationships between ultra performance liquid chromatography fingerprints and anti-bacterial activities of Rhizoma coptidis. Anal Chim Acta. 2009;634:279-85 pubmed publisher
    ..This work provides a general model of the combination of UPLC and microcalorimetry to study the spectrum-effect relationships of R. coptidis, which can be used to discover principle components of it on bioactivity...
  32. Panthama N, Kanokmedhakul S, Kanokmedhakul K. Galloyl and hexahydroxydiphenoyl esters of phenylpropanoid glucosides, phenylpropanoids and phenylpropanoid glucosides from rhizome of Balanophora fungosa. Chem Pharm Bull (Tokyo). 2009;57:1352-5 pubmed
    ..Their structures were determined on the basis of 1D and 2D spectroscopic data...
  33. Ghasemzadeh A, Jaafar H, Rahmat A. Identification and concentration of some flavonoid components in Malaysian young ginger (Zingiber officinale Roscoe) varieties by a high performance liquid chromatography method. Molecules. 2010;15:6231-43 pubmed publisher
    ..Results suggested a good flavonoid content and antioxidant activity potential in ginger leaves at 8 weeks after planting. The leaves of these ginger varieties could be useful for both food flavourings and in traditional medicine...
  34. Murrell C, Gerber E, Krebs C, Parepa M, Schaffner U, Bossdorf O. Invasive knotweed affects native plants through allelopathy. Am J Bot. 2011;98:38-43 pubmed publisher
    ..Preliminary results from laboratory studies suggest that allelopathy could play a role in this invasion...
  35. Hazra R, Ray K, Guha D. Inhibitory role of Acorus calamus in ferric chloride-induced epileptogenesis in rat. Hum Exp Toxicol. 2007;26:947-53 pubmed publisher
  36. Yang H, Chen S, Chen C, Wang S, Hseu Y. Alpinia pricei rhizome extracts induce apoptosis of human carcinoma KB cells via a mitochondria-dependent apoptotic pathway. Food Chem Toxicol. 2008;46:3318-24 pubmed publisher
    ..In this study, the ability of ethanol (70%) extracts of A. pricei rhizome (AP extracts) to induce apoptosis in cultured human carcinoma KB cells was investigated...
  37. Min Y, Yang M, Lee K, Kim K, Choi S, Lee K. Protoberberine alkaloids and their reversal activity of P-gp expressed multidrug resistance (MDR) from the rhizome of Coptis japonica Makino. Arch Pharm Res. 2006;29:757-61 pubmed
    Six protoberberine alkaloids were isolated from the chloroform layer of the rhizome of Coptis japonica Makino (Ranunculaceae)...
  38. Ma X, Gang D. Metabolic profiling of in vitro micropropagated and conventionally greenhouse grown ginger (Zingiber officinale). Phytochemistry. 2006;67:2239-55 pubmed
    ..Because ginger does not reproduce by seed, but is clonally propagated via rhizome division and replanting, it is susceptible to accumulation and transmittance of pathogens from generation to ..
  39. Yu F, Harada H, Yamasaki K, Okamoto S, Hirase S, Tanaka Y, et al. Isolation and functional characterization of a beta-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith. FEBS Lett. 2008;582:565-72 pubmed publisher
    ..coli and coexpressed it with ZSS2. When supplemented with mevalonate, the engineered E. coli produced a similar sesquiterpene profile to that produced in the in vitro enzyme assay, and the yield of beta-eudesmol reached 100 mg/L...
  40. Yang D, Wang Q, Ke L, Jiang J, Ying T. Antioxidant activities of various extracts of lotus (Nelumbo nuficera Gaertn) rhizome. Asia Pac J Clin Nutr. 2007;16 Suppl 1:158-63 pubmed
    Lotus rhizome powder was extracted with solvents of different polarities...
  41. Mukherjee D, Khatua T, Venkatesh P, Saha B, Mukherjee P. Immunomodulatory potential of rhizome and seed extracts of Nelumbo nucifera Gaertn. J Ethnopharmacol. 2010;128:490-4 pubmed publisher
    ..Nelumbo nucifera Gaertn. (Nymphaeaceae) is a well-known aquatic plant which has been used for the treatment of several disorders including skin disease, cough, inflammation, fever and many other disorders...
  42. Awang K, Ibrahim H, Rosmy Syamsir D, Mohtar M, Mat Ali R, Azah Mohamad Ali N. Chemical constituents and antimicrobial activity of the leaf and rhizome oils of Alpinia pahangensis Ridl., an endemic wild ginger from peninsular Malaysia. Chem Biodivers. 2011;8:668-73 pubmed publisher
    ..The major components of the rhizome oil were ?-selinene (11.60%), ?-pinene (10.87%), (E,E)-farnesyl acetate (8.65%), and ?-terpineol (6...
  43. Mishra R, Singh S. Reversible antifertility effect of aqueous rhizome extract of Curcuma longa L. in male laboratory mice. Contraception. 2009;79:479-87 pubmed publisher
    ..The purpose of the present study was to evaluate the antifertility potential of Curcuma longa L. in the male laboratory mouse...
  44. Sirat H, Basar N, Jani N. Chemical compositions of the rhizome oils of two Alpinia species of Malaysia. Nat Prod Res. 2011;25:982-6 pubmed publisher
    ..Eighteen compounds, representing 98.4% of the essential oil were identified in A. aquatica rhizome oil, with ?-sesquiphellandrene in 36.5% being the major constituent, while 20 compounds representing 99...
  45. Devaraj S, Esfahani A, Ismail S, Ramanathan S, Yam M. Evaluation of the antinociceptive activity and acute oral toxicity of standardized ethanolic extract of the rhizome of Curcuma xanthorrhiza Roxb. Molecules. 2010;15:2925-34 pubmed publisher
  46. Xie Z, Ma X, Gang D. Modules of co-regulated metabolites in turmeric (Curcuma longa) rhizome suggest the existence of biosynthetic modules in plant specialized metabolism. J Exp Bot. 2009;60:87-97 pubmed publisher
    ..co-regulated metabolite modules do exist in this plant, metabolic profiling analysis was performed on turmeric rhizome samples that were collected from 16 different growth and development treatments, which had significant impacts on ..
  47. Bashir S, Gilani A. Antiurolithic effect of Bergenia ligulata rhizome: an explanation of the underlying mechanisms. J Ethnopharmacol. 2009;122:106-16 pubmed publisher
    ..Bergenia ligulata is widely used plant in South Asia, mainly India and Pakistan, as a traditional medicine for treatment of urolithiasis...
  48. Xu W, Liu J, Li C, Wu H, Liu Y. Kaempferol-7-O-beta-D-glucoside (KG) isolated from Smilax china L. rhizome induces G2/M phase arrest and apoptosis on HeLa cells in a p53-independent manner. Cancer Lett. 2008;264:229-40 pubmed publisher
    Kaempferol-7-O-beta-D-glucoside (KG), a flavonoid glycoside, isolated from Smilax china L. rhizome, displayed marked anticancer activity on a panel of established cancer cells, of which, HeLa human cervix carcinoma cells were the most ..
  49. Zhao B, Chen Y, Sun X, Zhou M, Ding J, Zhan J, et al. Phenolic alkaloids from Menispermum dauricum rhizome protect against brain ischemia injury via regulation of GLT-1, EAAC1 and ROS generation. Molecules. 2012;17:2725-37 pubmed publisher
    Menispermum dauricum rhizome has been widely used in China to treat various cardiovascular and thrombosis disorders...
  50. Trinh H, Chae S, Joh E, Son K, Jeon S, Kim D. Tanshinones isolated from the rhizome of Salvia miltiorrhiza inhibit passive cutaneous anaphylaxis reaction in mice. J Ethnopharmacol. 2010;132:344-8 pubmed publisher
    The rhizome of Salvia miltiorrhiza Bunge (SM, family Labiatae), which contains tanshinones as main constituents, has been used as a cardiovascular and anti-inflammatory agent in Chinese medicine.
  51. Zhao M, Xu L, Che C. Alisolide, alisols O and P from the rhizome of Alisma orientale. Phytochemistry. 2008;69:527-32 pubmed
  52. Yemitan O, Izegbu M. Protective effects of Zingiber officinale (Zingiberaceae) against carbon tetrachloride and acetaminophen-induced hepatotoxicity in rats. Phytother Res. 2006;20:997-1002 pubmed
    The effect of the ethanol extract of the rhizome of Zingiber officinale was tested against carbon tetrachloride (CCl(4)) and acetaminophen-induced liver toxicities in rats...
  53. Armstrong J, Jones R, Armstrong W. Rhizome phyllosphere oxygenation in Phragmites and other species in relation to redox potential, convective gas flow, submergence and aeration pathways. New Phytol. 2006;172:719-31 pubmed
    ..In four species we examined the potential for the development of oxidized phyllospheres around rhizome apical buds, similar to the protective oxygenated rhizospheres around roots...
  54. Lee B, Trinh H, Jung K, Han S, Kim D. Inhibitory effects of steroidal timosaponins isolated from the rhizomes of Anemarrhena asphodeloides against passive cutaneous anaphylaxis reaction and pruritus. Immunopharmacol Immunotoxicol. 2010;32:357-63 pubmed publisher
    To investigate the antiallergic effect of the rhizome of Anemarrhena asphodeloides (AA, family Liliaceae), which was found to inhibit the mouse passive cutaneous anaphylaxis (PCA) reaction induced by the antigen-immunoglobulin E (IgE) ..
  55. Sukhirun N, Pluempanupat W, Bullangpoti V, Koul O. Bioefficacy of Alpinia galanga (Zingiberaceae) rhizome extracts, (E)-p-acetoxycinnamyl alcohol, and (E)-p-coumaryl alcohol ethyl ether against Bactrocera dorsalis (Diptera: Tephritidae) and the impact on detoxification enzyme activities. J Econ Entomol. 2011;104:1534-40 pubmed
    ..Insect CEs mediate insecticide resistance via their induction; therefore, inhibition of these enzymes by plant allelochemicals could be a useful alternative approach for the management of the pest in the field...
  56. Mishra K, Ganju L, Singh S. Anti-cellular and immunomodulatory potential of aqueous extract of Rhodiola imbricata rhizome. Immunopharmacol Immunotoxicol. 2012;34:513-8 pubmed publisher
    ..we have evaluated the anti-cellular and immunomodulatory potential of aqueous extract of Rhodiola imbricata rhizome (RAE)...
  57. Yu F, Wang N, He W, Chu Y, Dong M. Adaptation of rhizome connections in drylands: increasing tolerance of clones to wind erosion. Ann Bot. 2008;102:571-7 pubmed publisher
    Wind erosion is a severe stress for plants in drylands, but the mechanisms by which plants withstand erosion remain largely unknown. Here, the hypothesis is tested that maintaining rhizome connections helps plants to tolerate erosion.
  58. Yang W, Shim K, Choi M, Park S, Choi B, Chang M, et al. Novel effects of Nelumbo nucifera rhizome extract on memory and neurogenesis in the dentate gyrus of the rat hippocampus. Neurosci Lett. 2008;443:104-7 pubmed publisher
    ..In this study, we investigated the effect of Nelumbo nucifera rhizome extract on learning and memory function. A step-through passive avoidance test was performed with Wistar rats...
  59. Kim H, Yun Y, Ahn Y. Toxicity of atractylon and atractylenolide III Identified in Atractylodes ovata rhizome to Dermatophagoides farinae and Dermatophagoides pteronyssinus. J Agric Food Chem. 2007;55:6027-31 pubmed
    The acaricidal activity of materials derived from rhizome of Atractylodes ovata (Atractylodes macrocephala) toward adult Dermatophagoides farinae and Dermatophagoides pteronyssinus was examined using fabric-circle residual contact and ..
  60. Lee S, Choi S, Lee J, Lee D, Lee K. A new phenylpropane glycoside from the rhizome of Sparganium stoloniferum. Arch Pharm Res. 2010;33:515-21 pubmed publisher
    The purification of the MeOH extract from the rhizome of Sparganium stoloniferum Buch.-Hamil. (Sparganiaceae) using column chromatography furnished one new phenylpropanoid glycoside (7) and known phenolic compounds (1-6, and 8-13)...
  61. Jang C, Kamps T, Tang H, Bowers J, Lemke C, Paterson A. Evolutionary fate of rhizome-specific genes in a non-rhizomatous Sorghum genotype. Heredity (Edinb). 2009;102:266-73 pubmed publisher
    ..after the organ is lost? For Sorghum propinquum and Sorghum halepense genes that were previously shown to have rhizome-enriched expression, we have conducted comparative analysis of both coding regions and regulatory sequences in ..
  62. Ozgoli G, Goli M, Moattar F. Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. J Altern Complement Med. 2009;15:129-32 pubmed publisher
    ..To compare the effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea...
  63. Ban J, Cho S, Choi S, Ju H, Kim J, Bae K, et al. Neuroprotective effect of Smilacis chinae rhizome on NMDA-induced neurotoxicity in vitro and focal cerebral ischemia in vivo. J Pharmacol Sci. 2008;106:68-77 pubmed
    Previous work has shown that the Smilacis chinae rhizome (SCR) markedly inhibits amyloid beta protein (25-35)-induced neuronal cell damage in cultured rat cortical neurons...
  64. Moon L, Ha Y, Jang H, Kim H, Jun M, Kim Y, et al. Isoimperatorin, cimiside E and 23-O-acetylshengmanol-3-xyloside from Cimicifugae rhizome inhibit TNF-?-induced VCAM-1 expression in human endothelial cells: involvement of PPAR-? upregulation and PI3K, ERK1/2, and PKC signal pathways. J Ethnopharmacol. 2011;133:336-44 pubmed publisher
    The methanol extract of Cimicifugae Rhizome has been traditionally used in various disorders including inflammation.
  65. Ma X, Gang D. Metabolic profiling of turmeric (Curcuma longa L.) plants derived from in vitro micropropagation and conventional greenhouse cultivation. J Agric Food Chem. 2006;54:9573-83 pubmed
    ..Because it is a sterile triploid and is propagated vegetatively by rhizome division, turmeric is susceptible to pathogens that accumulate and are transmitted from generation to generation, ..
  66. Al Ja fari A, Vila R, Freixa B, Tomi F, Casanova J, Costa J, et al. Composition and antifungal activity of the essential oil from the rhizome and roots of Ferula hermonis. Phytochemistry. 2011;72:1406-13 pubmed publisher
    The analysis of the essential oil from rhizome and roots of Ferula hermonis Boiss. (Apiaceae) by GC-FID, GC-MS and ¹³C NMR allowed the identification of 79 constituents, more than 90% of the oil, the major one being ?-pinene (43...
  67. Jang C, Kamps T, Skinner D, Schulze S, Vencill W, Paterson A. Functional classification, genomic organization, putatively cis-acting regulatory elements, and relationship to quantitative trait loci, of sorghum genes with rhizome-enriched expression. Plant Physiol. 2006;142:1148-59 pubmed
    ..The finding that genes with rhizome-enriched expression are distributed across a wide range of functional categories suggests some degree of ..
  68. Upadhyay A, Chompoo J, Kishimoto W, Makise T, Tawata S. HIV-1 integrase and neuraminidase inhibitors from Alpinia zerumbet. J Agric Food Chem. 2011;59:2857-62 pubmed publisher
    ..These results suggest that alpinia could be used as a source of bioactive compounds against IN and NA and that DK and DDK may have possibilities in the design of drugs against these viral diseases...
  69. Wang K, Peng H, Lin E, Jin Q, Hua X, Yao S, et al. Identification of genes related to the development of bamboo rhizome bud. J Exp Bot. 2010;61:551-61 pubmed publisher
    ..In the present study, the differences in anatomical structure among rhizome buds, rhizome shoots, and bamboo shoots were compared, and several genes related to the development of the bamboo ..
  70. Taha M, Abdul A, Abdullah R, Ibrahim T, Abdelwahab S, Mohan S. Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the subtropical ginger (Zingiber zerumbet). Chem Biol Interact. 2010;186:295-305 pubmed publisher
    ..Therefore, ZER has great potential in the treatment of liver cancers...
  71. Yoo D, Kim W, Yoo K, Lee C, Choi J, Kang I, et al. Effects of Nelumbo nucifera rhizome extract on cell proliferation and neuroblast differentiation in the hippocampal dentate gyrus in a scopolamine-induced amnesia animal model. Phytother Res. 2011;25:809-15 pubmed publisher
    ..This study examined the effects of Nelumbo nucifera rhizome extracts (NRE) on cell proliferation and neuroblast differentiation in the hippocampal dentate gyrus (DG) of a ..
  72. Honda S, Aoki F, Tanaka H, Kishida H, Nishiyama T, Okada S, et al. Effects of ingested turmeric oleoresin on glucose and lipid metabolisms in obese diabetic mice: a DNA microarray study. J Agric Food Chem. 2006;54:9055-62 pubmed
    Turmeric, the rhizome of Curcuma longa L., has a wide range of effects on human health. Turmeric oleoresin, an extract of turmeric, is often used for flavoring and coloring...
  73. Nian H, Qin L, Chen W, Zhang Q, Zheng H, Wang Y. Protective effect of steroidal saponins from rhizome of Anemarrhena asphodeloides on ovariectomy-induced bone loss in rats. Acta Pharmacol Sin. 2006;27:728-34 pubmed
    ..To investigate the protective effect of steroidal saponins from Anemarrhena asphodeloides (ATS) on ovariectomy (OVX)-induced bone loss...
  74. Kim C, Kim M, Oh S, Lee S, Sun B, Choi G, et al. Effects of Atractylodes macrocephala Koidzumi rhizome on 3T3-L1 adipogenesis and an animal model of obesity. J Ethnopharmacol. 2011;137:396-402 pubmed publisher
    ..Atractylodes macrocephala Koidzumi (AMK) is an herbal medicine traditionally used for treatment of abdominal pain, gastrointestinal disease, obesity, and related complications...
  75. Isa N, Abdelwahab S, Mohan S, Abdul A, Sukari M, Taha M, et al. In vitro anti-inflammatory, cytotoxic and antioxidant activities of boesenbergin A, a chalcone isolated from Boesenbergia rotunda (L.) (fingerroot). Braz J Med Biol Res. 2012;45:524-30 pubmed
    ..7 at 50 µM. The significant biological activities observed in this study indicated that BA may be one of the agents responsible for the reported biological activities of B. rotunda crude extract...
  76. Sun L, Yan J, Nian Y, Zhou L, Zhang H, Qiu M. New triterpene diglycosides from the rhizome of Cimifuga foetida. Molecules. 2008;13:1712-21 pubmed
    ..D (6), cimidahurine (7) and alpha-D-glucopyranosyl-l-beta-D-fructofuranoside (8) were isolated from the rhizome of Cimicifuga foetida...
  77. Mishra K, Ganju L, Chanda S, Karan D, Sawhney R. Aqueous extract of Rhodiola imbricata rhizome stimulates Toll-like receptor 4, granzyme-B and Th1 cytokines in vitro. Immunobiology. 2009;214:27-31 pubmed publisher
    ..In this study, we have investigated the effect of aqueous extract of R. imbricata rhizome (RAE), on Toll-like receptor-4 (TLR-4) and intracellular granzyme-B expression in mouse splenocytes...
  78. Magalhaes L, Kapadia G, da Silva Tonuci L, Caixeta S, Parreira N, Rodrigues V, et al. In vitro schistosomicidal effects of some phloroglucinol derivatives from Dryopteris species against Schistosoma mansoni adult worms. Parasitol Res. 2010;106:395-401 pubmed publisher
    ..mansoni. The present results confirmed the traditional indications of rhizomes from Dryopteris species, which possess phloroglucinol compounds, in the treatment of tapeworm infections...
  79. Suksamrarn A, Ponglikitmongkol M, Wongkrajang K, Chindaduang A, Kittidanairak S, Jankam A, et al. Diarylheptanoids, new phytoestrogens from the rhizomes of Curcuma comosa: Isolation, chemical modification and estrogenic activity evaluation. Bioorg Med Chem. 2008;16:6891-902 pubmed publisher
  80. Asnani V, Verma R. Antioxidative effect of rhizome of Zinziber officinale on paraben induced lipid peroxidation: an in vitro study. Acta Pol Pharm. 2007;64:35-7 pubmed
    Antioxidative effect of aqueous extract of rhizome of Ginger (Zinziber officinale) was examined on p-hydroxybenzoic acid (paraben) induced lipid peroxidation...
  81. Ganie S, Haq E, Hamid A, Qurishi Y, Mahmood Z, Zargar B, et al. Carbon tetrachloride induced kidney and lung tissue damages and antioxidant activities of the aqueous rhizome extract of Podophyllum hexandrum. BMC Complement Altern Med. 2011;11:17 pubmed publisher
    ..Carbon tetrachloride (CCl4) is a well known toxicant and exposure to this chemical is known to induce oxidative stress and causes tissue damage by the formation of free radicals...
  82. Shindo K, Kato M, Kinoshita A, Kobayashi A, Koike Y. Analysis of antioxidant activities contained in the Boesenbergia pandurata Schult. Rhizome. Biosci Biotechnol Biochem. 2006;70:2281-4 pubmed
    The rhizome of Boesenbergia pandurata Schult. was found to possess potent antioxidant activity in a rat brain homogenate model...
  83. ElRokh E, Yassin N, El Shenawy S, Ibrahim B. Antihypercholesterolaemic effect of ginger rhizome (Zingiber officinale) in rats. Inflammopharmacology. 2010;18:309-15 pubmed publisher
    ..Many herbal medicinal products have potential hypocholesterolaemic activity and encouraging safety profiles. However, only a limited amount of clinical research exists to support their efficacy...