photoperiod

Summary

Summary: The time period of daily exposure that an organism receives from daylight or artificial light. It is believed that photoperiodic responses may affect the control of energy balance and thermoregulation.

Top Publications

  1. ncbi FT protein movement contributes to long-distance signaling in floral induction of Arabidopsis
    Laurent Corbesier
    Max Planck Institute for Plant Breeding Research, Carl von Linne Weg 10, D 50829 Cologne, Germany
    Science 316:1030-3. 2007
  2. ncbi The late elongated hypocotyl mutation of Arabidopsis disrupts circadian rhythms and the photoperiodic control of flowering
    R Schaffer
    John Innes Centre, Norwich, United Kingdom
    Cell 93:1219-29. 1998
  3. ncbi Hd3a, a rice ortholog of the Arabidopsis FT gene, promotes transition to flowering downstream of Hd1 under short-day conditions
    Shoko Kojima
    Institute of the Society for Techno Innovation of Agriculture, Forestry and Fisheries, Tsukuba, Ibaraki, 305 0854 Japan
    Plant Cell Physiol 43:1096-105. 2002
  4. ncbi CONSTANS mediates between the circadian clock and the control of flowering in Arabidopsis
    P Suárez-López
    John Innes Centre, Norwich Research Park, Colney Lane, Norwich NR4 7UH, UK
    Nature 410:1116-20. 2001
  5. ncbi Regulation and identity of florigen: FLOWERING LOCUS T moves center stage
    Franziska Turck
    Max Planck Institute for Plant Breeding, D 50829 Cologne, Germany
    Annu Rev Plant Biol 59:573-94. 2008
  6. doi Thyrotrophin in the pars tuberalis triggers photoperiodic response
    Nobuhiro Nakao
    Division of Biomodelling, Graduate School of Bioagricultural Sciences, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8601, Japan
    Nature 452:317-22. 2008
  7. pmc FLOWERING LOCUS T protein may act as the long-distance florigenic signal in the cucurbits
    Ming Kuem Lin
    Section of Plant Biology, College of Biological Sciences, University of California, Davis, California 95616, USA
    Plant Cell 19:1488-506. 2007
  8. ncbi CO/FT regulatory module controls timing of flowering and seasonal growth cessation in trees
    Henrik Böhlenius
    Umea Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, S 90183 Umeå, Sweden
    Science 312:1040-3. 2006
  9. ncbi Light-induced hormone conversion of T4 to T3 regulates photoperiodic response of gonads in birds
    Takashi Yoshimura
    Division of Biomodeling, Graduate School of Bioagricultural Sciences, Nagoya University, Furo cho, Chikusa ku, Nagoya, 464 8601, Japan
    Nature 426:178-81. 2003
  10. ncbi Arabidopsis, the Rosetta stone of flowering time?
    Gordon G Simpson
    Department of Cell and Developmental Biology, John Innes Centre, Norwich, NR4 7UH, UK
    Science 296:285-9. 2002

Research Grants

  1. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2009
  2. `
    Timothy Bartness; Fiscal Year: 1999
  3. COMPARATIVE STUDIES OF VOCAL CONTROL
    ELIOT BRENOWITZ; Fiscal Year: 2004
  4. MOLECULAR ANALYSIS OF FLOWERING GENES OF PHARBITIS NIL
    Anath Das; Fiscal Year: 1990
  5. Photoperiod Brain and Behavior
    Randy Nelson; Fiscal Year: 2009
  6. Photoperiod Brain and Behavior
    Randy J Nelson; Fiscal Year: 2010
  7. Protease regulation of ovarian recrudescence
    KELLY ANSLEY YOUNG; Fiscal Year: 2010
  8. Environmental regulation of estrogen dependent aggression
    Brian C Trainor; Fiscal Year: 2011
  9. Environmental regulation of estrogen dependent aggression
    Brian C Trainor; Fiscal Year: 2010
  10. Environmental regulation of estrogen dependent aggression
    Brian C Trainor; Fiscal Year: 2010

Detail Information

Publications343 found, 100 shown here

  1. ncbi FT protein movement contributes to long-distance signaling in floral induction of Arabidopsis
    Laurent Corbesier
    Max Planck Institute for Plant Breeding Research, Carl von Linne Weg 10, D 50829 Cologne, Germany
    Science 316:1030-3. 2007
    ..Finally, we provide evidence that FT does not activate an intermediate messenger in leaves. We conclude that FT protein acts as a long-distance signal that induces Arabidopsis flowering...
  2. ncbi The late elongated hypocotyl mutation of Arabidopsis disrupts circadian rhythms and the photoperiodic control of flowering
    R Schaffer
    John Innes Centre, Norwich, United Kingdom
    Cell 93:1219-29. 1998
    ..circadian clock regulation of gene expression and leaf movements and caused flowering to occur independently of photoperiod. LHY was shown to encode a MYB DNA-binding protein...
  3. ncbi Hd3a, a rice ortholog of the Arabidopsis FT gene, promotes transition to flowering downstream of Hd1 under short-day conditions
    Shoko Kojima
    Institute of the Society for Techno Innovation of Agriculture, Forestry and Fisheries, Tsukuba, Ibaraki, 305 0854 Japan
    Plant Cell Physiol 43:1096-105. 2002
    ....
  4. ncbi CONSTANS mediates between the circadian clock and the control of flowering in Arabidopsis
    P Suárez-López
    John Innes Centre, Norwich Research Park, Colney Lane, Norwich NR4 7UH, UK
    Nature 410:1116-20. 2001
    ..In addition, the late flowering phenotype of such mutants is corrected by overexpressing CO. Thus, CO acts between the circadian clock and the control of flowering, suggesting mechanisms by which day length regulates flowering time...
  5. ncbi Regulation and identity of florigen: FLOWERING LOCUS T moves center stage
    Franziska Turck
    Max Planck Institute for Plant Breeding, D 50829 Cologne, Germany
    Annu Rev Plant Biol 59:573-94. 2008
    ..Finally, we discuss conservation of FT function in other species and how variation in its regulation could generate different flowering behaviors...
  6. doi Thyrotrophin in the pars tuberalis triggers photoperiodic response
    Nobuhiro Nakao
    Division of Biomodelling, Graduate School of Bioagricultural Sciences, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8601, Japan
    Nature 452:317-22. 2008
    Molecular mechanisms regulating animal seasonal breeding in response to changing photoperiod are not well understood...
  7. pmc FLOWERING LOCUS T protein may act as the long-distance florigenic signal in the cucurbits
    Ming Kuem Lin
    Section of Plant Biology, College of Biological Sciences, University of California, Davis, California 95616, USA
    Plant Cell 19:1488-506. 2007
    ..moschata plants established that Cmo-FTL1 and Cmo-FTL2 are regulated by photoperiod at the level of movement into the phloem and not by transcription...
  8. ncbi CO/FT regulatory module controls timing of flowering and seasonal growth cessation in trees
    Henrik Böhlenius
    Umea Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, S 90183 Umeå, Sweden
    Science 312:1040-3. 2006
    ..This regulatory mechanism can explain the ecogenetic variation in a highly adaptive trait: the critical daylength for growth cessation displayed by aspen trees sampled across a latitudinal gradient spanning northern Europe...
  9. ncbi Light-induced hormone conversion of T4 to T3 regulates photoperiodic response of gonads in birds
    Takashi Yoshimura
    Division of Biomodeling, Graduate School of Bioagricultural Sciences, Nagoya University, Furo cho, Chikusa ku, Nagoya, 464 8601, Japan
    Nature 426:178-81. 2003
    ..These findings demonstrate that light-induced Dio2 expression in the MBH may be involved in the photoperiodic response of gonads in Japanese quail...
  10. ncbi Arabidopsis, the Rosetta stone of flowering time?
    Gordon G Simpson
    Department of Cell and Developmental Biology, John Innes Centre, Norwich, NR4 7UH, UK
    Science 296:285-9. 2002
    ..This framework provides the basis to understand the evolution of different reproductive strategies and how floral pathways interact through seasonal progression...
  11. pmc Comparative genomics of flowering time pathways using Brachypodium distachyon as a model for the temperate grasses
    Janet A Higgins
    Department of Crop Genetics, John Innes Centre, Norwich, United Kingdom
    PLoS ONE 5:e10065. 2010
    ..Pathways include those detecting and responding to the environmental cues of day length (photoperiod) and extended periods of low temperature (vernalization)...
  12. doi Regulation of flowering in rice: two florigen genes, a complex gene network, and natural variation
    Hiroyuki Tsuji
    Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara 630 0192, Japan
    Curr Opin Plant Biol 14:45-52. 2011
    ..This review summarizes photoperiodic flowering control in rice, including the interaction of complex layers of gene networks contributed from evolutionarily unique factors and the regulatory adaptation of conserved factors...
  13. doi A pair of floral regulators sets critical day length for Hd3a florigen expression in rice
    Hironori Itoh
    Photosynthesis and Photobiology Research Unit, National Institute of Agrobiological Sciences, Tsukuba, Japan
    Nat Genet 42:635-8. 2010
    ..Thus, two distinct gating mechanisms--of the floral promoter Ehd1 and the floral repressor Ghd7--could enable manipulation of slight differences in day length to control Hd3a transcription with a critical day-length threshold...
  14. ncbi The timing of developmental transitions in plants
    Isabel Bäurle
    Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4 7UH, UK
    Cell 125:655-64. 2006
    ..Parallel themes are beginning to emerge from a molecular comparison of these two developmental transitions...
  15. ncbi Cloning of the Arabidopsis clock gene TOC1, an autoregulatory response regulator homolog
    C Strayer
    Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA
    Science 289:768-71. 2000
    ..TOC1 is itself circadianly regulated and participates in a feedback loop to control its own expression...
  16. ncbi Distinct roles of CONSTANS target genes in reproductive development of Arabidopsis
    A Samach
    John Innes Centre, Norwich NR4 7UH, UK
    Science 288:1613-6. 2000
    ..The SOC1 and FT genes are also regulated by a second flowering-time pathway that acts independently of CO. Thus, early target genes of CO define common components of distinct flowering-time pathways...
  17. pmc Chronic phase shifts of the photoperiod throughout pregnancy programs glucose intolerance and insulin resistance in the rat
    Tamara J Varcoe
    Research Centre for Reproductive Health, Robinson Institute, University of Adelaide, Adelaide, South Australia, Australia
    PLoS ONE 6:e18504. 2011
    ..Pregnant rats were exposed to chronic phase shifts (CPS) in their photoperiod every 3-4 days throughout gestation and the first week after birth...
  18. ncbi Photoperiodic control of seasonality in birds
    A Dawson
    Centre for Ecology and Hydrology, Huntingdon, Cambridgeshire, UK
    J Biol Rhythms 16:365-80. 2001
    This review examines how birds use the annual cycle in photoperiod to ensure that seasonal events--breeding, molt, and song production--happen at the appropriate time of year...
  19. ncbi Transcription factor PIF4 controls the thermosensory activation of flowering
    S Vinod Kumar
    Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4 7UH, UK
    Nature 484:242-5. 2012
    ..How this occurs is, however, not understood, because the major pathway known to upregulate FT, the photoperiod pathway, is not required for thermal acceleration of flowering...
  20. pmc A morning-specific phytohormone gene expression program underlying rhythmic plant growth
    Todd P Michael
    Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, USA
    PLoS Biol 6:e225. 2008
    ..growth rates of the embryonic stem (hypocotyl) are maximal at different times of day, depending on external photoperiod and the internal circadian clock...
  21. pmc The GIGANTEA-regulated microRNA172 mediates photoperiodic flowering independent of CONSTANS in Arabidopsis
    Jae Hoon Jung
    Molecular Signaling Laboratory, Department of Chemistry, Seoul National University, Seoul, Korea
    Plant Cell 19:2736-48. 2007
    ..Notably, miR172 abundance is regulated by photoperiod via GI-mediated miRNA processing...
  22. ncbi Adaptation of photoperiodic control pathways produces short-day flowering in rice
    Ryosuke Hayama
    Laboratory of Plant Molecular Genetics, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma 630 0101, Japan
    Nature 422:719-22. 2003
    ....
  23. pmc Data assimilation constrains new connections and components in a complex, eukaryotic circadian clock model
    Alexandra Pokhilko
    School of Biological Sciences, University of Edinburgh, Mayfield Road, Edinburgh, UK
    Mol Syst Biol 6:416. 2010
    ..The multiple PRR genes of Arabidopsis uncouple events in the late night from light-driven responses in the day, increasing the flexibility of rhythmic regulation...
  24. pmc Ehd1, a B-type response regulator in rice, confers short-day promotion of flowering and controls FT-like gene expression independently of Hd1
    Kazuyuki Doi
    Plant Breeding Laboratory, Faculty of Agriculture, Kyushu University, Fukuoka 812 8581, Japan
    Genes Dev 18:926-36. 2004
    ..Microarray analysis further revealed a few MADS box genes downstream of Ehd1. Our results indicate that a novel two-component signaling cascade is integrated into the conserved pathway in the photoperiodic control of flowering in rice...
  25. pmc Two coordinately regulated homologs of FLOWERING LOCUS T are involved in the control of photoperiodic flowering in soybean
    Fanjiang Kong
    Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Harbin, China
    Plant Physiol 154:1220-31. 2010
    ..by the PHYA-mediated photoperiodic regulation system, and the GmFT5a expression was also regulated by a photoperiod-independent system in LD...
  26. pmc CONSTANS activates SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 through FLOWERING LOCUS T to promote flowering in Arabidopsis
    Seung Kwan Yoo
    Plant Signaling Network Research Center, School of Life Sciences and Biotechnology, Korea University, Seoul
    Plant Physiol 139:770-8. 2005
    ..Taken together, these data suggest that CO activates SOC1 through FT to promote flowering in Arabidopsis...
  27. ncbi CONSTANS acts in the phloem to regulate a systemic signal that induces photoperiodic flowering of Arabidopsis
    Hailong An
    Max Planck Institute for Plant Breeding, Carl von Linne Weg 10, D 50829 Cologne, Germany
    Development 131:3615-26. 2004
    ....
  28. doi Effects of genetic perturbation on seasonal life history plasticity
    Amity M Wilczek
    Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA
    Science 323:930-4. 2009
    ..Environmental signals control the timing of this transition, creating a critical window of acute sensitivity to genetic and climatic change that may be common for seasonally regulated life history traits...
  29. ncbi Move on up, it's time for change--mobile signals controlling photoperiod-dependent flowering
    Yasushi Kobayashi
    Department of Molecular Biology, Max Planck Institute for Developmental Biology, D 72076, Tubingen, Germany
    Genes Dev 21:2371-84. 2007
    ..and rice, we today understand the essentials of two central issues in plant biology: how the appropriate photoperiod generates an inductive stimulus based on an external coincidence mechanism, and the nature of the mobile ..
  30. pmc Circadian control of carbohydrate availability for growth in Arabidopsis plants at night
    Alexander Graf
    Department of Metabolic Biology, John Innes Centre, Norwich NR4 7UH, United Kingdom
    Proc Natl Acad Sci U S A 107:9458-63. 2010
    ..Thus, starch degradation is under circadian control to ensure that carbohydrate availability is maintained until the next anticipated dawn, and this control is necessary for maintaining plant productivity...
  31. ncbi Natural variation in Hd17, a homolog of Arabidopsis ELF3 that is involved in rice photoperiodic flowering
    Kazuki Matsubara
    National Institute of Agrobiological Sciences, Tsukuba, Ibaraki, Japan
    Plant Cell Physiol 53:709-16. 2012
    ....
  32. pmc Photic entrainment of period mutant mice is predicted from their phase response curves
    Julie S Pendergast
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235 1634, USA
    J Neurosci 30:12179-84. 2010
    ..Together, these results demonstrate that PRCs are powerful tools for predicting and understanding photic entrainment of circadian mutant mice...
  33. pmc Terminal flower2, an Arabidopsis homolog of heterochromatin protein1, counteracts the activation of flowering locus T by constans in the vascular tissues of leaves to regulate flowering time
    Shinobu Takada
    Research Institute for Biological Sciences, Okayama 716 1241, Japan
    Plant Cell 15:2856-65. 2003
    ....
  34. doi A molecular switch for photoperiod responsiveness in mammals
    Hugues Dardente
    Institute of Biological and Environmental Sciences, Zoology Building, Tillydrone Avenue, University of Aberdeen, Aberdeen AB24 2TZ, UK
    Curr Biol 20:2193-8. 2010
    Seasonal synchronization based on day length (photoperiod) allows organisms to anticipate environmental change. Photoperiodic decoding relies on circadian clocks, but the underlying molecular pathways have remained elusive [1]...
  35. pmc A phase response curve to single bright light pulses in human subjects
    Sat Bir S Khalsa
    Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Physiol 549:945-52. 2003
    ..Phase shifts derived using the melatonin onsets showed larger magnitudes than those derived from the melatonin offsets. These data provide a comprehensive characterization of the human PRC under highly controlled laboratory conditions...
  36. ncbi Ancestral TSH mechanism signals summer in a photoperiodic mammal
    Elodie A Hanon
    School of Biological Sciences, University of Aberdeen, Aberdeen, Scotland
    Curr Biol 18:1147-52. 2008
    ..In mammals this provides the missing link between the pineal melatonin signal and thyroid-dependent seasonal biology...
  37. pmc Phytochrome mediates the external light signal to repress FT orthologs in photoperiodic flowering of rice
    Takeshi Izawa
    Laboratory of Plant Molecular Genetics, Nara Institute of Science and Technology, Ikoma, Nara 630 0101, Japan
    Genes Dev 16:2006-20. 2002
    ..experiments revealed that a rice counterpart gene of Arabidopsis CONSTANS (CO), named PHOTOPERIOD SENSITIVITY 1 (Heading date 1) [SE1 (Hd1)], functions as an output of circadian clocks...
  38. pmc Involvement of thyrotropin in photoperiodic signal transduction in mice
    Hiroko Ono
    Laboratory of Animal Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8601, Japan
    Proc Natl Acad Sci U S A 105:18238-42. 2008
    ..In mammals, nocturnal melatonin secretion provides an endocrine signal of the photoperiod to the PT that contains melatonin receptors in high density, but the interface between the melatonin signal ..
  39. ncbi Constitutive expression of the CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) gene disrupts circadian rhythms and suppresses its own expression
    Z Y Wang
    Department of Molecular, Cell, and Developmental Biology, UCLA, Los Angeles, California 90095 1606, USA
    Cell 93:1207-17. 1998
    ..Furthermore, the expression of both endogenous CCA1 and the related LHY gene was suppressed. Our results suggest that CCA1 is a part of a feedback loop that is closely associated with the circadian clock in Arabidopsis...
  40. pmc Photoperiod and reproductive condition are associated with changes in RFamide-related peptide (RFRP) expression in Syrian hamsters (Mesocricetus auratus)
    Alex O Mason
    Department of Psychology, University of California, Berkeley, CA 94720 1650, USA
    J Biol Rhythms 25:176-85. 2010
    ..In the present study, the authors explored the relationship between RFRP expression, photoperiod exposure, and reproductive condition/hormonal status...
  41. doi Arabidopsis plants having defects in nonsense-mediated mRNA decay factors UPF1, UPF2, and UPF3 show photoperiod-dependent phenotypes in development and stress responses
    Chuan Shi
    Department of Medical Engineering and Biotechnology, University of Applied Sciences, Jena, 07745 Germany
    J Integr Plant Biol 54:99-114. 2012
    ..tomato strain DC3000. Under the long (16 h) photoperiod condition, Arabidopsis having a defect in NMD factors exhibited altered morphologies of various organs, ..
  42. doi RFamide-related peptide and its cognate receptor in the sheep: cDNA cloning, mRNA distribution in the hypothalamus and the effect of photoperiod
    H Dardente
    School of Biological Sciences, Aberdeen University, Scotland, UK
    J Neuroendocrinol 20:1252-9. 2008
    ..Syrian hamsters, hypothalamic RFamide-related peptide (RFRP) expression is increased by exposure to long photoperiod. Because, opposite to hamsters, sheep are short-day breeders, we predicted that a conserved role in mammalian ..
  43. ncbi A pair of related genes with antagonistic roles in mediating flowering signals
    Y Kobayashi
    Department of Botany, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Science 286:1960-2. 1999
    Flowering in Arabidopsis is promoted via several interacting pathways. A photoperiod-dependent pathway relays signals from photoreceptors to a transcription factor gene, CONSTANS (CO), which activates downstream meristem identity genes ..
  44. doi Genetic analysis and QTL detection of reproductive period and post-flowering photoperiod responses in soybean
    Lirui Cheng
    The National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, 12 Zhongguancun South Street, Beijing, China
    Theor Appl Genet 123:421-9. 2011
    ..To investigate the inheritance and photoperiod response of RP in soybean, the F(1), F(2), and F(2:3) populations derived from nine crosses were developed...
  45. doi Modulation of sugar metabolism by an INDETERMINATE DOMAIN transcription factor contributes to photoperiodic flowering in Arabidopsis
    Pil Joon Seo
    Molecular Signaling Laboratory, Department of Chemistry, Seoul National University, Seoul 151 742, Korea
    Plant J 65:418-29. 2011
    ..SUS4 expression also responds to photoperiodic signals. Notably, the AtIDD8 gene is suppressed by sugar deprivation. Therefore, we conclude that AtIDD8 regulation of sugar transport and metabolism is linked to photoperiodic flowering...
  46. pmc The pea GIGAS gene is a FLOWERING LOCUS T homolog necessary for graft-transmissible specification of flowering but not for responsiveness to photoperiod
    Valerie Hecht
    School of Plant Science, University of Tasmania, Hobart, Tasmania 7001, Australia
    Plant Cell 23:147-61. 2011
    ..different expression patterns with respect to developmental timing, tissue specificity, and response to photoperiod and differ in their activity in transgenic Arabidopsis thaliana, suggesting they may have different functions...
  47. pmc The FLOWERING LOCUS T-like gene family in barley (Hordeum vulgare)
    Sebastien Faure
    John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, United Kingdom
    Genetics 176:599-609. 2007
    ..in integrating flowering signals in Arabidopsis because its expression is regulated antagonistically by the photoperiod and vernalization pathways...
  48. ncbi The CCAAT binding factor can mediate interactions between CONSTANS-like proteins and DNA
    Orna Ben-Naim
    Department of Biology, Technion Israel Institute of Technology, Haifa 32000, Israel
    Plant J 46:462-76. 2006
    ..CBFs are therefore likely to recruit COL proteins to their DNA target motifs in planta...
  49. pmc Arabidopsis circadian clock and photoperiodism: time to think about location
    Takato Imaizumi
    Department of Biology, University of Washington, 24 Kincaid Hall, Box 351800, Seattle, WA 98195 1800, USA
    Curr Opin Plant Biol 13:83-9. 2010
    ..Subsequently, CO protein induces FLOWERING LOCUS T (FT) expression which leads to flowering. It is emerging that both CO and FT expression are intricately controlled by groups of transcription factors with overlapping functions...
  50. pmc Daylength and circadian effects on starch degradation and maltose metabolism
    Yan Lu
    Department of Botany, University of Wisconsin, Madison, Wisconsin 53706, USA
    Plant Physiol 138:2280-91. 2005
    ..Light is necessary for the cycling of transcript levels and maltose levels. Under continuous darkness, these genes were barely expressed, and no cycling of maltose levels was observed...
  51. ncbi Biology of mammalian photoperiodism and the critical role of the pineal gland and melatonin
    B Malpaux
    UMR 6073 INRA CNRS Université François Rabelais, Physiologie de la Reproduction et des Comportements, Nouzilly, France
    J Biol Rhythms 16:336-47. 2001
    ..In addition, this network appears to undergo morphological changes between seasons...
  52. pmc COP1 and ELF3 control circadian function and photoperiodic flowering by regulating GI stability
    Jae Woong Yu
    Department of Plant Science and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151 921, Korea
    Mol Cell 32:617-30. 2008
    ..we present data showing that COP1 acts with ELF3 to mediate day length signaling from CRY2 to GI within the photoperiod flowering pathway...
  53. pmc Circadian rhythms confer a higher level of fitness to Arabidopsis plants
    Rachel M Green
    Department of Molecular, Cell and Developmental Biology, P O Box 160606, University of California Los Angeles, Los Angeles, CA 90095 1606, USA
    Plant Physiol 129:576-84. 2002
    ..In addition, we demonstrate that two other circadian rhythm mutants, LHY-ox and elf3, have low-viability phenotypes. Our findings demonstrate the adaptive advantage of circadian rhythms in Arabidopsis...
  54. ncbi Photoreceptor regulation of CONSTANS protein in photoperiodic flowering
    Federico Valverde
    Max Planck Institute for Plant Breeding, Carl von Linne Weg 10, D 50829 Cologne, Germany
    Science 303:1003-6. 2004
    ..This layer of regulation refines the circadian rhythm in CO messenger RNA and is central to the mechanism by which day length controls flowering...
  55. pmc HvVRN2 responds to daylength, whereas HvVRN1 is regulated by vernalization and developmental status
    Ben Trevaskis
    Commonwealth Scientific and Industrial Research Organization, Division of Plant Industry, Canberra, Australian Capital Territory 2601, Australia
    Plant Physiol 140:1397-405. 2006
    ..We conclude that the vernalization response is mediated through HvVRN1, whereas HvZCCTa and HvZCCTb respond to daylength cues to repress flowering under long days in nonvernalized plants...
  56. pmc The FT-like ZCN8 Gene Functions as a Floral Activator and Is Involved in Photoperiod Sensitivity in Maize
    Xin Meng
    Pioneer Hi Bred International, A DuPont Business, Johnston, Iowa 50131 0552
    Plant Cell 23:942-60. 2011
    ..ZCN8 stood out as the only ZCN having the requisite characteristics for possessing florigenic activity. In photoperiod sensitive tropical lines, ZCN8 transcripts were strongly upregulated in a diurnal manner under floral-inductive ..
  57. ncbi The art of entrainment
    Till Roenneberg
    Institute for Medical Psychology, University of Munich, Germany
    J Biol Rhythms 18:183-94. 2003
    ..The results of this basic research will help us to understand temporal ecology and will allow us to improve conditions for humans in industrialized societies...
  58. doi Hd3a and RFT1 are essential for flowering in rice
    Reina Komiya
    Laboratory of Plant Molecular Genetics, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma 630 0101, Japan
    Development 135:767-74. 2008
    ..These results indicate that Hd3a and RFT1 act as floral activators under SD conditions, and that RFT1 expression is partly regulated by chromatin modification...
  59. pmc The molecular biology of seasonal flowering-responses in Arabidopsis and the cereals
    Aaron Greenup
    Commonwealth Scientific and Industrial Research Organization, Division of Plant Industry, Canberra, Australian Capital Territory 2601, Australia
    Ann Bot 103:1165-72. 2009
    ..FT is a promoter of flowering activated by long days and by warm conditions. FLC represses FT to delay flowering until plants experience winter...
  60. pmc A circadian rhythm set by dusk determines the expression of FT homologs and the short-day photoperiodic flowering response in Pharbitis
    Ryosuke Hayama
    Max Planck Institute for Plant Breeding Research, D 50829 Cologne, Germany
    Plant Cell 19:2988-3000. 2007
    ....
  61. doi Long-distance, graft-transmissible action of Arabidopsis FLOWERING LOCUS T protein to promote flowering
    Michitaka Notaguchi
    Department of Botany, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto, 606 8502, Japan
    Plant Cell Physiol 49:1645-58. 2008
    ..The sequence and structure of mRNA are not of critical importance for the long-distance action of the FT gene. These observations led to the conclusion that the FT protein, but not mRNA, is the essential component of florigen...
  62. doi Population-based resequencing reveals that the flowering time adaptation of cultivated barley originated east of the Fertile Crescent
    Huw Jones
    National Institute for Agricultural Botany, Cambridge, United Kingdom
    Mol Biol Evol 25:2211-9. 2008
    ....
  63. pmc ELF4 is required for oscillatory properties of the circadian clock
    Harriet G McWatters
    Department of Plant Sciences, University of Oxford, Oxford OX1 3RB, United Kingdom
    Plant Physiol 144:391-401. 2007
    ..ELF4, therefore, can be considered a component of the central CCA1/LHY-TOC1 feedback loop in the plant circadian clock...
  64. doi Interactions of the serotonin and circadian systems: nature and nurture in rhythms and blues
    C M Ciarleglio
    Silvio O Conte Center for Neuroscience Research, Vanderbilt University, Nashville, TN, USA
    Neuroscience 197:8-16. 2011
    ....
  65. pmc Coincident light and clock regulation of pseudoresponse regulator protein 37 (PRR37) controls photoperiodic flowering in sorghum
    Rebecca L Murphy
    Department of Biochemistry and Biophysics, Texas A and M University, College Station, TX 77843, USA
    Proc Natl Acad Sci U S A 108:16469-74. 2011
    ..Sorghum is a short-day tropical species that exhibits substantial photoperiod sensitivity and delayed flowering in long days...
  66. pmc A long noncoding RNA regulates photoperiod-sensitive male sterility, an essential component of hybrid rice
    Jihua Ding
    National Key Laboratory of Crop Genetic Improvement and National Centre of Plant Gene Research, Huazhong Agriculture University, Wuhan 430070, China
    Proc Natl Acad Sci U S A 109:2654-9. 2012
    ..A major component that facilitated the development of hybrids was a mutant showing photoperiod-sensitive male sterility (PSMS) with its fertility regulated by day length...
  67. doi Light inputs shape the Arabidopsis circadian system
    Bénédicte Wenden
    School of Biological Sciences, University of Edinburgh, Mayfield Road, Edinburgh EH93JH, UK
    Plant J 66:480-91. 2011
    ..Both experimental systems illustrate how profoundly the light input pathways affect the plant circadian clock, and provide strong experimental manipulations to understand critical steps in the plant clock mechanism...
  68. ncbi Involvement of rice cryptochromes in de-etiolation responses and flowering
    Fumiaki Hirose
    Department of Plant Physiology, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki, 305 8602 Japan
    Plant Cell Physiol 47:915-25. 2006
    ..In addition, OsCRY2 antisense transgenic rice flowered later than WT under both long-day and short-day conditions, indicating that Oscry2 is involved in the promotion of flowering time in rice...
  69. pmc Cloning of gonadotropin-releasing hormone I complementary DNAs in songbirds facilitates dissection of mechanisms mediating seasonal changes in reproduction
    T J Stevenson
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
    Endocrinology 150:1826-33. 2009
    ..Furthermore, we provide evidence for photoperiod-dependent regulation of GNRH1 mRNA in male starlings...
  70. ncbi Short photoperiods impair spatial learning and alter hippocampal dendritic morphology in adult male white-footed mice (Peromyscus leucopus)
    Leah M Pyter
    Department of Neuroscience and Institute of Behavioral Medicine Research, Ohio State University, Columbus, Ohio 43210, USA
    J Neurosci 25:4521-6. 2005
    ..memory in rodents and because of the potential for seasonal plasticity in the hippocampus, we hypothesized that photoperiod alters hippocampal morphology to affect spatial learning and memory...
  71. pmc Influence of photoperiod on hormones, behavior, and immune function
    James C Walton
    Department of Neuroscience, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Front Neuroendocrinol 32:303-19. 2011
    ..Thus, melatonin is the fulcrum mediating redistribution of energetic investment among physiological processes to maximize fitness and survival...
  72. doi Ehd3, encoding a plant homeodomain finger-containing protein, is a critical promoter of rice flowering
    Kazuki Matsubara
    National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305 8602, Japan
    Plant J 66:603-12. 2011
    Oryza sativa (rice) flowers in response to photoperiod, and is a facultative short-day (SD) plant...
  73. pmc Interactions between cognition and circadian rhythms: attentional demands modify circadian entrainment
    Howard J Gritton
    Department of Psychology, University of Michigan, Ann Arbor, MI 48109 1043, USA
    Behav Neurosci 123:937-48. 2009
    ..These results form the basis for future research on the role of neuronal systems mediating interactions between cognitive activity and circadian rhythms...
  74. ncbi Photoperiod affects hepatic and renal cadmium accumulation, metallothionein induction, and cadmium toxicity in the wild bank vole (Clethrionomys glareolus)
    T Włostowski
    Institute of Biology, University of Białystok, Swierkowa 20B, Białystok 15 950, Poland
    Ecotoxicol Environ Saf 58:29-36. 2004
    ..injury, tubular cell degeneration) of bank voles fed the highest dose of dietary Cd only under the moderate photoperiod. The same voles also exhibited the highest values of hepatic and renal Cd, Cd not bound to MT, and renal lipid ..
  75. doi QTL mapping for photoperiod insensitivity of a Japanese soybean landrace Sakamotowase
    Baohui Liu
    the Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Harbin, China
    J Hered 101:251-6. 2010
    ..The objective of this study was to map the novel gene(s) for photoperiod insensitivity in the Japanese soybean landrace Sakamotowase...
  76. ncbi The effect of temperature, photoperiod, and light quality on gluconasturtiin concentration in watercress (Nasturtium officinale R. Br.)
    Gerard Engelen-Eigles
    Department of Horticultural Science, University of Minnesota, 1970 Folwell Avenue, 305 Alderman Hall, St Paul, Minnesota 55108, USA
    J Agric Food Chem 54:328-34. 2006
    ..to long (16 h) or short (8 h) days, to red (R) or far-red (FR) light given during the main long day photoperiod, and finally to R or FR light given at the end of the main photoperiod...
  77. doi Acute induction of Eya3 by late-night light stimulation triggers TSHβ expression in photoperiodism
    Koh hei Masumoto
    Laboratory for Systems Biology, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minamimachi, Chuo Ku, Kobe, Hyogo 650 0047, Japan
    Curr Biol 20:2199-206. 2010
    Living organisms detect seasonal changes in day length (photoperiod) [1-3] and alter their physiological functions accordingly to fit seasonal environmental changes...
  78. ncbi Disrupted circadian rhythms in VIP- and PHI-deficient mice
    Christopher S Colwell
    Mental Retardation Res Ctr, Univ of California Los Angeles, 760 Westwood Plaza, Los Angeles, CA 90024 1759, USA
    Am J Physiol Regul Integr Comp Physiol 285:R939-49. 2003
    ..is seen in the split-activity patterns expressed by the mutant mice when they were exposed to a skeleton photoperiod. In addition, the VIP/PHI-deficient mice exhibited deficits in the response of their circadian system to light...
  79. doi Melanopsin expression in dopamine-melatonin neurons of the premammillary nucleus of the hypothalamus and seasonal reproduction in birds
    S W Kang
    Department of Animal Science, University of Minnesota, St Paul, MN 55108, USA
    Neuroscience 170:200-13. 2010
    ..The results implicate tOPN4x in hypothalamic PMM DA-MEL neurons as an important component of the photoreceptive system regulating reproductive activity in temperate zone birds...
  80. doi Biological clocks and regulation of seasonal reproduction and migration in birds
    Vinod Kumar
    Department of Science and Technology, University of Delhi, Delhi 110 007, India
    Physiol Biochem Zool 83:827-35. 2010
    ..Environmental cues, particularly photoperiod, appear to have a more direct role than simply entraining the clock to calendar time...
  81. ncbi Melatonin regulates type 2 deiodinase gene expression in the Syrian hamster
    Florent G Revel
    Département de Neurobiologie des Rythmes, Centre National de la Recherche Scientifique Unite Mixte de Recherche, 7168 LC2, Institut des Neurosciences Cellulaires et Integratives, Universite Louis Pasteur, 67084 Strasbourg Cedex, France
    Endocrinology 147:4680-7. 2006
    In seasonal species, photoperiod organizes various physiological processes, including reproduction...
  82. pmc Time's arrow flies like a bird: two paradoxes for avian circadian biology
    Vincent M Cassone
    Department of Biology, Thomas Hunt Morgan Building, University of Kentucky, 675 Rose Street, Lexington, KY 40506, USA
    Gen Comp Endocrinol 163:109-16. 2009
    ..Experimental analyses that address these paradoxes will shed light on the roles the biological clock play in birds and in vertebrates in general...
  83. ncbi VA opsin-based photoreceptors in the hypothalamus of birds
    Stephanie Halford
    Circadian and Visual Neuroscience, Nuffield Laboratory of Ophthalmology, University of Oxford, Headley Way, Oxford OX3 9DU, UK
    Curr Biol 19:1396-402. 2009
    ..Most recently, photoperiod has been shown to alter the activity of the pars tuberalis to release thyrotrophin, which ultimately drives a ..
  84. pmc Regulation of flowering time in Arabidopsis by K homology domain proteins
    Todd C Mockler
    Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 101:12759-64. 2004
    ..In addition to FLK, the expression of two other KH domain genes are modestly affected by the flk mutation, suggesting a possible involvement of more than one KH domain protein in the regulation of flowering time in Arabidopsis...
  85. doi A maize CONSTANS-like gene, conz1, exhibits distinct diurnal expression patterns in varied photoperiods
    Theresa A Miller
    Department of Biological Sciences, Marquette University, Milwaukee, WI 53201 1881, USA
    Planta 227:1377-88. 2008
    ..mays L. ssp. parviglumis Iltis & Doebley), a plant requiring short day photoperiods to flower. While photoperiod sensitive landraces of maize exist, post-domestication breeding included efforts to grow maize in a broad range ..
  86. ncbi Validation of the VRN-H2/VRN-H1 epistatic model in barley reveals that intron length variation in VRN-H1 may account for a continuum of vernalization sensitivity
    Peter Szucs
    Department of Crop and Soil Science, Oregon State University, 253 Crop Science Building, Corvallis, OR 97331, USA
    Mol Genet Genomics 277:249-61. 2007
    ..both VRN-H (Calicuchima-sib) loci and measured the flowering time of unvernalized F(2) progeny under long-day photoperiod. We assessed whether the spring growth habit of Calicuchima-sib is an exception to the two-locus epistatic ..
  87. pmc Quantitative analysis of regulatory flexibility under changing environmental conditions
    Kieron D Edwards
    School of Biological Sciences, University of Edinburgh, Edinburgh, UK
    Mol Syst Biol 6:424. 2010
    ..Molecular clock components in Arabidopsis thaliana showed complex, photoperiod-dependent regulation, which was analysed by comparison with three contrasting models...
  88. ncbi Circannual rhythms in birds
    Eberhard Gwinner
    Max Planck Research Center for Ornithology, Department of Biological Rhythms and Behavior, Von der Tann Str 7, D 82346 Andechs, Germany
    Curr Opin Neurobiol 13:770-8. 2003
    ..Whether or not the rhythm is expressed depends on day length (photoperiod), which thus represents an important permissive factor in the process of rhythm generation...
  89. doi The circadian clock regulates the photoperiodic response of hypocotyl elongation through a coincidence mechanism in Arabidopsis thaliana
    Yusuke Niwa
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Chikusa ku, Nagoya 464 8601, Japan
    Plant Cell Physiol 50:838-54. 2009
    ..during the night-time of short days, due to coincidence between the internal (circadian rhythm) and external (photoperiod) time cues...
  90. pmc The PAS/LOV protein VIVID supports a rapidly dampened daytime oscillator that facilitates entrainment of the Neurospora circadian clock
    Mark Elvin
    Faculty of Life Sciences, The University of Manchester, Manchester, M13 9PT, United Kingdom
    Genes Dev 19:2593-605. 2005
    ..Consistent with this, loss of VVD yields a clock whose performance follows the simple predictions of earlier models, and overexpression of VVD restores rhythmicity in the light and sensitivity of phase to the duration of the photoperiod.
  91. ncbi A thermosensory pathway controlling flowering time in Arabidopsis thaliana
    Miguel A Blázquez
    Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037, USA
    Nat Genet 33:168-71. 2003
    ..Molecular-genetic studies in Arabidopsis thaliana have focused on daily light duration, or photoperiod, and transient exposure to winter-like temperatures, or vernalization...
  92. ncbi The Arabidopsis homeobox gene, ATHB16, regulates leaf development and the sensitivity to photoperiod in Arabidopsis
    Yan Wang
    Evolutionary Biology Centre, Department of Physiological Botany, Uppsala University, Villavagen 6, S 752 36 Uppsala, Sweden
    Dev Biol 264:228-39. 2003
    ..Furthermore, the flowering time response to photoperiod was increased in plants with reduced ATHB16 levels but reduced in plants with elevated ATHB16 levels, ..
  93. ncbi Universal florigenic signals triggered by FT homologues regulate growth and flowering cycles in perennial day-neutral tomato
    Eliezer Lifschitz
    Department of Biology, Technion I I T Haifa, 32000, Israel
    J Exp Bot 57:3405-14. 2006
    ..The florigen paradigm was conceived in photoperiod-sensitive plants: nevertheless it implies that although activated by different stimuli in different flowering ..
  94. pmc Novel loci control variation in reproductive timing in Arabidopsis thaliana in natural environments
    Cynthia Weinig
    Department of Ecology and Evolutionary Biology, Brown University, Providence, Rhode Island 02912, USA
    Genetics 162:1875-84. 2002
    ..days in the chamber were expressed only in fall-germinating cohorts, suggesting differential involvement of the photoperiod pathway in different seasonal environments...
  95. ncbi Seasonal encoding by the circadian pacemaker of the SCN
    Henk Tjebbe VanderLeest
    Department of Molecular Cell Biology, Lab for Neurophysiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Curr Biol 17:468-73. 2007
    ..48 and 3.85 hr, respectively). The data indicate that coding for day length involves plasticity within SCN neuronal networks in which the phase distribution of oscillating neurons carries information on the photoperiod's duration.
  96. pmc Low-temperature and daylength cues are integrated to regulate FLOWERING LOCUS T in barley
    Megan N Hemming
    Commonwealth Scientific and Industrial Research Organisation, Division of Plant Industry, Canberra, Australian Capital Territory 2601, Australia
    Plant Physiol 147:355-66. 2008
    ..We conclude that low-temperature and daylength flowering-response pathways are integrated to control expression of HvFT1 in barley, and that this might occur through regulation of HvVRN2 activity...
  97. doi Photoperiod and acute energy deficits interact on components of the thyroid hormone system in hypothalamic tanycytes of the Siberian hamster
    Annika Herwig
    Rowett Institute of Nutrition and Health, University of Aberdeen, Bucksburn, Aberdeen AB21 9SB, UK
    Am J Physiol Regul Integr Comp Physiol 296:R1307-15. 2009
    ..Eight weeks in an SD photoperiod induced weight loss in the Siberian hamster...
  98. ncbi Spatiotemporal heterogeneity in the electrical activity of suprachiasmatic nuclei neurons and their response to photoperiod
    T M Brown
    University of Manchester, Manchester, UK
    J Biol Rhythms 24:44-54. 2009
    ..We demonstrate that under a symmetrical (12 h light:12 h dark) photoperiod, cells in the dorsal SCN are less tightly synchronized than those in the ventral SCN...
  99. doi Short photoperiod-induced decrease of histamine H3 receptors facilitates activation of hypothalamic neurons in the Siberian hamster
    P Barrett
    Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen AB21 9SB, United Kingdom
    Endocrinology 150:3655-63. 2009
    ..Here we show for the first time that a shift from long summer-like to short winter-like photoperiod, which induces physiological adaptation to winter in the Siberian hamster, including a body weight decrease of ..
  100. pmc Genetic control of photoperiod sensitivity in maize revealed by joint multiple population analysis
    Nathan D Coles
    Department of Crop Science, North Carolina State University, Raleigh, North Carolina 27695, USA
    Genetics 184:799-812. 2010
    Variation in maize for response to photoperiod is related to geographical adaptation in the species...
  101. doi The thyrotropin-releasing hormone secretory system in the hypothalamus of the Siberian hamster in long and short photoperiods
    F J P Ebling
    School of Biomedical Sciences, University of Nottingham Medical School, Nottingham, UK
    J Neuroendocrinol 20:576-86. 2008
    ..of TRH producing neurones and TRH-R1 receptor expressing cells in the hypothalamus, and investigated whether photoperiod regulated this system...

Research Grants93

  1. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2009
    ..hair follicles;ie, the dermis, subcutaneous fat tissue, extracellular matrix) and external environment (photoperiod, temperature) in regulating the regenerative hair follicle waves...
  2. `
    Timothy Bartness; Fiscal Year: 1999
    ..We have chosen a model of naturally occurring obesity-- photoperiod-induced seasonal obesity in Siberian hamsters (Phodopus sungorus sungorus)...
  3. COMPARATIVE STUDIES OF VOCAL CONTROL
    ELIOT BRENOWITZ; Fiscal Year: 2004
    ..Seasonal changes of environmental factors, such as photoperiod, have a profound effect on birds and most other animals...
  4. MOLECULAR ANALYSIS OF FLOWERING GENES OF PHARBITIS NIL
    Anath Das; Fiscal Year: 1990
    The goal of this research is to understand the molecular mechanism of floral induction in plants. How photoperiod, a crucial controlling factor, regulates floral induction in a short-day plant Pharbitis nil is the subject of the ..
  5. Photoperiod Brain and Behavior
    Randy Nelson; Fiscal Year: 2009
    ..We recently established an experimental model of photoperiod-induced plasticity in brain structure and function...
  6. Photoperiod Brain and Behavior
    Randy J Nelson; Fiscal Year: 2010
    ..We recently established an experimental model of photoperiod-induced plasticity in brain structure and function...
  7. Protease regulation of ovarian recrudescence
    KELLY ANSLEY YOUNG; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: Ovarian recrudescence is a natural process stimulated by changes in photoperiod (the number of hours of light per day) whereby the atrophied and non-functional ovary returns to a fully ..
  8. Environmental regulation of estrogen dependent aggression
    Brian C Trainor; Fiscal Year: 2011
    ..This proposal, submitted by a new investigator, examines how a photoperiod modulates the effects of estrogens on aggression...
  9. Environmental regulation of estrogen dependent aggression
    Brian C Trainor; Fiscal Year: 2010
    ..This proposal, submitted by a new investigator, examines how a photoperiod modulates the effects of estrogens on aggression...
  10. Environmental regulation of estrogen dependent aggression
    Brian C Trainor; Fiscal Year: 2010
    ..This proposal, submitted by a new investigator, examines how a photoperiod modulates the effects of estrogens on aggression...
  11. Environmental regulation of estrogen dependent aggression
    Brian C Trainor; Fiscal Year: 2011
    ..This proposal, submitted by a new investigator, examines how a photoperiod modulates the effects of estrogens on aggression...
  12. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2010
    ..hair follicles;ie, the dermis, subcutaneous fat tissue, extracellular matrix) and external environment (photoperiod, temperature) in regulating the regenerative hair follicle waves...
  13. The Role of Melatonin in Natural Neuroprotection
    Christine Schwartz; Fiscal Year: 2012
    ..To achieve this aim, I will artificially manipulate the photoperiod (light or dark) and temperature (4 or 25oC) of the hibernation environment and determine the effect on ..
  14. BRAIN-GUT PEPTIDES IN FEMALE REPRODUCTION-OVULATION
    Satya Kalra; Fiscal Year: 1990
    ..Although it is well known that the neural clock (NC) entrained to the daily photoperiod activates LHRH secretion during the critical period, the origin and route of transmission of neural signals to ..
  15. MELATONIN AND CEREBRAL BLOOD FLOW AUTOREGULATION
    Mohan Viswanathan; Fiscal Year: 1999
    Melatonin, a neuroendocrine transducer of photoperiod, is used by mammals to establish and maintain circadian rhythms. Melatonin receptors which mediate these functions are believed to be located in the hypothalamus...
  16. MELATONIN AND CEREBRAL BLOOD FLOW AUTOREGULATION
    Mohan Viswanathan; Fiscal Year: 2000
    Melatonin, a neuroendocrine transducer of photoperiod, is used by mammals to establish and maintain circadian rhythms. Melatonin receptors which mediate these functions are believed to be located in the hypothalamus...
  17. MECHANISMS GOVERNING ONSET OF OVARIAN FUNCTION
    Kathleen Ryan; Fiscal Year: 1990
    ..of control groups which are the same age and body weight as the pubertal females, but due to the nonstimulatory photoperiod, they are 10-12 weeks from puberty...
  18. PHOTOPERIODIC CONTROL OF OBESITY
    Timothy Bartness; Fiscal Year: 1990
    ..melatonin directly affects hamster fat cell metabolism and that "secondary hormones" that are altered by the photoperiod (melatonin), in turn affect body and lipid mass changes due to changes in the daylength...
  19. PHOTOPERIODIC CONTROL OF OBESITY
    Timothy Bartness; Fiscal Year: 1991
    ..melatonin directly affects hamster fat cell metabolism and that "secondary hormones" that are altered by the photoperiod (melatonin), in turn affect body and lipid mass changes due to changes in the daylength...
  20. Circadian Modulation of Drug-Seeking Behavior
    HEIKO JANSEN; Fiscal Year: 2009
    ..We propose the following three Specific Aims: 1) Determine the contribution of the SCN and photoperiod to time-of-day variation in the extinction rate of cocaine-induced CPP and DAT protein levels 2) Determine the ..
  21. FAT CELL PROLIFERATION IN OBESITY--MODULATING FACTORS
    Roy Martin; Fiscal Year: 1999
    ..accompanies old age: Wistar rats; 3) diet-induced obesity: high fat diet (HFD)-fed Wistar rats; 4) seasonal (photoperiod)-induced obesity: Syrian hamsters; and 5) hyperplastic model: Guinea pig...
  22. Circadian Modulation of Drug-Seeking Behavior
    Heiko T Jansen; Fiscal Year: 2010
    ..We propose the following three Specific Aims: 1) Determine the contribution of the SCN and photoperiod to time-of-day variation in the extinction rate of cocaine-induced CPP and DAT protein levels 2) Determine the ..
  23. Circadian Modulation of Drug-Seeking Behavior
    HEIKO JANSEN; Fiscal Year: 2007
    ..We propose the following three Specific Aims: 1) Determine the contribution of the SCN and photoperiod to time-of-day variation in the extinction rate of cocaine-induced CPP and DAT protein levels 2) Determine the ..
  24. NEUROENDOCRINE CONTROL OF SEASONALITY
    Robert Goodman; Fiscal Year: 1991
    ..Based on previous work, we have proposed that seasonal alterations of fertility in the ewe result from a photoperiod-induced shift in the neural systems controlling LH secretion...
  25. NEUROENDOCRINE CONTROL OF SEASONALITY
    Robert Goodman; Fiscal Year: 1993
    ..Based on previous work, we have proposed that seasonal alterations of fertility in the ewe result from a photoperiod-induced shift in the neural systems controlling LH secretion...
  26. NEUROENDOCRINE CONTROL OF SEASONALITY
    Robert Goodman; Fiscal Year: 1992
    ..Based on previous work, we have proposed that seasonal alterations of fertility in the ewe result from a photoperiod-induced shift in the neural systems controlling LH secretion...
  27. ENVIRONMENT, BEHAVIOR, AND REPRODUCTION
    Randy Nelson; Fiscal Year: 2000
    ..this proposal are two-fold: (1) to identity more precisely the external cues that act alone or in concert with photoperiod to regulate seasonal breeding male deer mice and prairie voles, and (2) to ascertain the relative costs and ..
  28. ENVIRONMENT, BEHAVIOR, AND REPRODUCTION IN RODENTS
    Randy Nelson; Fiscal Year: 1993
    ..this proposal are two-fold: (1) to identity more precisely the external cues that act alone or in concert with photoperiod to regulate seasonal breeding male deer mice and prairie voles, and (2) to ascertain the relative costs and ..
  29. ENVIRONMENT, BEHAVIOR, AND REPRODUCTION
    Randy Nelson; Fiscal Year: 1999
    ..this proposal are two-fold: (1) to identity more precisely the external cues that act alone or in concert with photoperiod to regulate seasonal breeding male deer mice and prairie voles, and (2) to ascertain the relative costs and ..
  30. ENVIRONMENT, BEHAVIOR, AND REPRODUCTION
    Randy Nelson; Fiscal Year: 2000
    ..this proposal are two-fold: (1) to identity more precisely the external cues that act alone or in concert with photoperiod to regulate seasonal breeding male deer mice and prairie voles, and (2) to ascertain the relative costs and ..
  31. NEUROENDOCRINOLOGY OF PUBERTY
    Douglas Foster; Fiscal Year: 1990
    ..the pineal gland of the neonatal lamb does not produce a pattern of melatonin that accords with the prevailing photoperiod. The light requirements for puberty will be studied; lambs, rendered nonphotoperiodic by denervation of the ..
  32. ENVIRONMENTAL CONTROL OF SEASONAL WEIGHT CYCLES
    George Wade; Fiscal Year: 1990
    ..The principal environmental cue for seasonal body weight change in hamsters is photoperiod, the number of hours of light per 24-hr period...
  33. MECHANISMS GOVERNING INITIATION OF OVULATION
    Douglas Foster; Fiscal Year: 1980
    ..Using a model system to be developed during the course of the research, the influence of environment, photoperiod, and body weight on the mechanism governing sensitivity to the negative feedback of estradiol during sexual ..
  34. METHOXYINDOLES IN RETINA--FUNCTION AND REGULATION
    P Iuvone; Fiscal Year: 1999
    ..Together with dopamine, melatonin appears to play a pivotal role in the modulation by photoperiod and circadian clocks of visual sensitivity and metabolism in the photoreceptor-pigment epithelial complex...
  35. METHOXYINDOLES IN RETINA--FUNCTION AND REGULATION
    P Iuvone; Fiscal Year: 2002
    ..Together with dopamine, melatonin appears to play a pivotal role in the modulation by photoperiod and circadian clocks of visual sensitivity and metabolism in the photoreceptor-pigment epithelial complex...
  36. DEVELOPING AND IMPROVING INSTITUTIONAL ANIMAL RESOURCES
    GEORGE BJOTVEDT; Fiscal Year: 1991
    ..These chambers would allow experimental manipulation of variables such as temperature, photoperiod, and humidity to assess effect of these factors on various aspects of the biology of animals including their ..
  37. METHOXYINDOLES IN RETINA--FUNCTION AND REGULATION
    P Iuvone; Fiscal Year: 2000
    ..Together with dopamine, melatonin appears to play a pivotal role in the modulation by photoperiod and circadian clocks of visual sensitivity and metabolism in the photoreceptor-pigment epithelial complex...
  38. METHOXYINDOLES IN RETINA--FUNCTION AND REGULATION
    P Iuvone; Fiscal Year: 2000
    ..Together with dopamine, melatonin appears to play a pivotal role in the modulation by photoperiod and circadian clocks of visual sensitivity and metabolism in the photoreceptor-pigment epithelial complex...
  39. METHOXYINDOLES IN RETINA--FUNCTION AND REGULATION
    P Iuvone; Fiscal Year: 2001
    ..Together with dopamine, melatonin appears to play a pivotal role in the modulation by photoperiod and circadian clocks of visual sensitivity and metabolism in the photoreceptor-pigment epithelial complex...
  40. HORMONE ACTIONS ON BEHAVIORS
    George Wade; Fiscal Year: 1991
    ..In many mammals, it is the photoperiod (day length) that signals seasonal change and drives these physiological and behavioral fluctuations...
  41. HORMONE ACTIONS ON BEHAVIORS
    George Wade; Fiscal Year: 1992
    ..In many mammals, it is the photoperiod (day length) that signals seasonal change and drives these physiological and behavioral fluctuations...
  42. COMPARATIVE STUDIES OF VOCAL CONTROL
    ELIOT BRENOWITZ; Fiscal Year: 2002
    ..Seasonal changes of environmental factors, such as photoperiod, have a profound effect on birds and most other animals...
  43. COMPARATIVE STUDIES OF VOCAL CONTROL
    ELIOT BRENOWITZ; Fiscal Year: 2000
    ..Seasonal changes of environmental factors, such as photoperiod, have a profound effect on birds and most other animals...
  44. COMPARATIVE STUDIES OF VOCAL CONTROL
    ELIOT BRENOWITZ; Fiscal Year: 2001
    ..Seasonal changes of environmental factors, such as photoperiod, have a profound effect on birds and most other animals...
  45. Massively parallel sequencing of the diapause transcriptome in Aedes albopictus
    Peter Armbruster; Fiscal Year: 2009
    ..PUBLIC HEALTH RELEVANCE Photoperiodic diapause refers to the ability of insects to measure day length (photoperiod) as a cue for initiating seasonally appropriate patterns of developmental arrest...
  46. Massively parallel sequencing of the diapause transcriptome in Aedes albopictus
    Christine Elsik; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE Photoperiodic diapause refers to the ability of insects to measure day length (photoperiod) as a cue for initiating seasonally appropriate patterns of developmental arrest...
  47. ETHANOL AND THE NEUROBIOLOGY OF TEMPERATURE REGULATION
    LARRY CRAWSHAW; Fiscal Year: 1990
    ..the effect of ethanol on temperature regulation during, and under changes in a variety of conditions--time of photoperiod, acute tolerance, chronic tolerance and withdrawal...
  48. Behavioral modification of respiratory development
    MATTHEW GDOVIN; Fiscal Year: 1999
    ..interface to take lung breaths, metamorphosis is arrested in spite of adequate temperature, food, oxygen, and photoperiod. The developmental transfer from gill to lung breathing during metamorphosis has been described, but the neural ..
  49. MATERNAL INFLUENCE ON DEVELOPING 24-HOUR PERIODICITY
    STEVEN REPPERT; Fiscal Year: 1990
    ..Testicular weight will be used to study the influence of prenatal photoperiod on postnatal reproductive development...
  50. CNS MELATONIN TARGETS AND PHOTOPERIOD-INDUCED OBESITY
    Timothy Bartness; Fiscal Year: 2000
    ..activated by melatonin and located in the three brain sites that show melatonin binding?, and 3) Can these putative efferent projection fields be verified using retrograde tract tracing combined with c-Fos immunocytochemical techniques? ..
  51. CNS MELATONIN TARGETS AND PHOTOPERIOD-INDUCED OBESITY
    Timothy Bartness; Fiscal Year: 1999
    ..activated by melatonin and located in the three brain sites that show melatonin binding?, and 3) Can these putative efferent projection fields be verified using retrograde tract tracing combined with c-Fos immunocytochemical techniques? ..
  52. REPRODUCTIVE CONSEQUENCES OF NEURAL MELATONIN RECEPTORS
    MARILYN DUNCAN; Fiscal Year: 1990
    ..transducer since its daily pattern of secretion is regulated by light, particularly by daylength or photoperiod. This hormone travels through the circulation to receptors on target organs whose location has not been clearly ..
  53. NEUROENDOCRINE/IMMUNE INTERACTIONS: ROLE OF MELATONIN
    STEVEN YELLON; Fiscal Year: 2001
    ..rhythm, the major focus of the proposal is to test the hypothesis that the pineal melatonin rhythm mediates photoperiod control of innate and adaptive immune system functions...
  54. NEUROENDOCRINE/IMMUNE INTERACTIONS: ROLE OF MELATONIN
    STEVEN YELLON; Fiscal Year: 2002
    ..rhythm, the major focus of the proposal is to test the hypothesis that the pineal melatonin rhythm mediates photoperiod control of innate and adaptive immune system functions...
  55. NEUROENDOCRINE/IMMUNE INTERACTIONS: ROLE OF MELATONIN
    STEVEN YELLON; Fiscal Year: 2000
    ..rhythm, the major focus of the proposal is to test the hypothesis that the pineal melatonin rhythm mediates photoperiod control of innate and adaptive immune system functions...
  56. PHOTOPERIODIC CONTROL OF OBESITY
    Timothy Bartness; Fiscal Year: 1992
    ..The overall purpose of the proposed research is to examine the photoperiod-induced control of regional fat pad-specific changes in lipid storage and how this process contributes to the ..
  57. PHOTOPERIODIC CONTROL OF OBESITY
    Timothy Bartness; Fiscal Year: 1993
    ..The overall purpose of the proposed research is to examine the photoperiod-induced control of regional fat pad-specific changes in lipid storage and how this process contributes to the ..
  58. NEUROENDOCRINE BASIS OF SEASONAL BREEDING
    Michael Lehman; Fiscal Year: 1990
    ..In the Suffolk ewe, environmental cues conveying daylength (photoperiod) and endogenous steroid hormones regulate the activity of the LHRH pulse generator, and are responsible for the ..
  59. NEURAL PATHWAYS FROM PHOTORECEPTORS TO THE PITUITARY
    Gary Jackson; Fiscal Year: 1990
    The overall specific aims are to define the photoperiod conditions which permit expression of endogenous circannual rhythms of reproductive activity (anestrus versus estrous cycles as defined by blood progesterone) and prolactin ..
  60. COMPARATIVE STUDIES OF VOCAL CONTROL
    ELIOT BRENOWITZ; Fiscal Year: 1999
    ..Seasonal changes of environmental factors, such as photoperiod, have a profound effect on birds and most other animals...
  61. Photoperiod affects retinal function
    Chad R Jackson; Fiscal Year: 2012
    ..2009). Recently, it was also shown that the melanopsin system in zebrafish is responsive to alterations in photoperiod (Matos-Cruz, V. et al., 2011)...
  62. Methoxyindoles in Retina: Function and Regulation
    P Iuvone; Fiscal Year: 2004
    ..dopamine, melatonin appears to play a pivotal role in the modulation of visual sensitivity and adaptation by photoperiod and circadian clocks...
  63. Methoxyindoles in Retina: Function and Regulation
    P Iuvone; Fiscal Year: 2006
    ..dopamine, melatonin appears to play a pivotal role in the modulation of visual sensitivity and adaptation by photoperiod and circadian clocks...
  64. Methoxyindoles in Retina: Function and Regulation
    P Iuvone; Fiscal Year: 2005
    ..dopamine, melatonin appears to play a pivotal role in the modulation of visual sensitivity and adaptation by photoperiod and circadian clocks...
  65. Methoxyindoles in Retina: Function and Regulation
    P Iuvone; Fiscal Year: 2003
    ..dopamine, melatonin appears to play a pivotal role in the modulation of visual sensitivity and adaptation by photoperiod and circadian clocks...
  66. NEUROPEPTIDES RECEPTORS AND PHOTOPERIODISM
    ERIC BITTMAN; Fiscal Year: 1992
    ..Responsiveness to opiate agonists and antagonists depends upon photoperiod, however, and daylength may influence the concentration of neuropeptides including endogenous opiates...
  67. Photoperiod, melatonin, and reproductive aging
    NED PLACE; Fiscal Year: 2006
    ..The research proposed seeks to determine how photoperiod and the pineal gland hormone melatonin affect female reproductive aging...
  68. PHOTOPERIODIC CONTROL OF OBESITY
    TIMOTHY JON BARTNESS; Fiscal Year: 2010
    Siberian hamsters develop a naturally-occurring, photoperiod-induced obesity in long summer days (LDs) and that is reversed by short winter days (SDs)...
  69. TRAINING PROGRAM IN REPRODUCTIVE BIOLOGY
    Jon Levine; Fiscal Year: 2000
    ..Control of Reproductive Processes- neural mechanisms which mediate effects of environmental variables, such as photoperiod, on reproductive processes...
  70. TRAINING PROGRAM IN REPRODUCTIVE BIOLOGY
    Jon Levine; Fiscal Year: 2001
    ..Control of Reproductive Processes- neural mechanisms which mediate effects of environmental variables, such as photoperiod, on reproductive processes...
  71. NEUROENDOCRINOLOGY OF PUBERTY
    STEVEN YELLON; Fiscal Year: 1990
    ..model, provides an unique opportunity for this proposal because sexual maturation is profoundly influenced by photoperiod; changes in day length can delay or initiate puberty...
  72. TRAINING PROGRAM IN REPRODUCTIVE BIOLOGY
    Jon Levine; Fiscal Year: 2003
    ..Control of Reproductive Processes- neural mechanisms which mediate effects of environmental variables, such as photoperiod, on reproductive processes...
  73. TRAINING PROGRAM IN REPRODUCTIVE BIOLOGY
    Jon Levine; Fiscal Year: 1999
    ..Control of Reproductive Processes- neural mechanisms which mediate effects of environmental variables, such as photoperiod, on reproductive processes...
  74. PHOTOPERIODIC CONTROL OF OBESITY
    TIMOTHY JON BARTNESS; Fiscal Year: 2011
    Siberian hamsters develop a naturally-occurring, photoperiod-induced obesity in long summer days (LDs) and that is reversed by short winter days (SDs)...
  75. PHOTOPERIODIC CONTROL OF OBESITY
    Timothy Bartness; Fiscal Year: 2009
    Description (provided by applicant): Siberian hamsters develop a naturally-occurring, photoperiod-induced obesity in long summer days (LDs) and that is reversed by short winter days (SDs)...
  76. TRAINING PROGRAM IN REPRODUCTIVE BIOLOGY
    Jon Levine; Fiscal Year: 2002
    ..Control of Reproductive Processes- neural mechanisms which mediate effects of environmental variables, such as photoperiod, on reproductive processes...