Top Publications

  1. ncbi Detecting influenza epidemics using search engine query data
    Jeremy Ginsberg
    Google Inc, 1600 Amphitheatre Parkway, Mountain View, California 94043, USA
    Nature 457:1012-4. 2009
  2. ncbi Climate warming and disease risks for terrestrial and marine biota
    C Drew Harvell
    Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY 14853, USA
    Science 296:2158-62. 2002
  3. pmc Absolute humidity modulates influenza survival, transmission, and seasonality
    Jeffrey Shaman
    College of Oceanic and Atmospheric Sciences, Oregon State University, Corvallis, OR 97331, USA
    Proc Natl Acad Sci U S A 106:3243-8. 2009
  4. pmc Influenza virus transmission is dependent on relative humidity and temperature
    Anice C Lowen
    Department of Microbiology, Mount Sinai School of Medicine, New York, New York, USA
    PLoS Pathog 3:1470-6. 2007
  5. pmc Positional cloning of the wheat vernalization gene VRN1
    L Yan
    Department of Agronomy and Range Science, University of California, Davis 95616, USA
    Proc Natl Acad Sci U S A 100:6263-8. 2003
  6. ncbi Tracking apex marine predator movements in a dynamic ocean
    B A Block
    Stanford University, Biology Department, Hopkins Marine Station, Pacific Grove, California 93950, USA
    Nature 475:86-90. 2011
  7. ncbi Seasonality and the dynamics of infectious diseases
    Sonia Altizer
    Institute of Ecology, University of Georgia, Athens, GA, USA
    Ecol Lett 9:467-84. 2006
  8. ncbi Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis
    Michael F Holick
    Vitamin D, Skin, and Bone Research Laboratory, Section of Endocrinology, Diabetes, and Nutrition, Department of Medicine, Boston University School of Medicine, Boston, MA 02118 2394, USA
    Am J Clin Nutr 79:362-71. 2004
  9. ncbi Climate change and human health: present and future risks
    Anthony J McMichael
    National Centre for Epidemiology and Population Health, The Australian National University, Canberra 0200, Australia
    Lancet 367:859-69. 2006
  10. ncbi Arabidopsis, the Rosetta stone of flowering time?
    Gordon G Simpson
    Department of Cell and Developmental Biology, John Innes Centre, Norwich, NR4 7UH, UK
    Science 296:285-9. 2002

Detail Information

Publications359 found, 100 shown here

  1. ncbi Detecting influenza epidemics using search engine query data
    Jeremy Ginsberg
    Google Inc, 1600 Amphitheatre Parkway, Mountain View, California 94043, USA
    Nature 457:1012-4. 2009
    ..This approach may make it possible to use search queries to detect influenza epidemics in areas with a large population of web search users...
  2. ncbi Climate warming and disease risks for terrestrial and marine biota
    C Drew Harvell
    Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY 14853, USA
    Science 296:2158-62. 2002
    ..To improve our ability to predict epidemics in wild populations, it will be necessary to separate the independent and interactive effects of multiple climate drivers on disease impact...
  3. pmc Absolute humidity modulates influenza survival, transmission, and seasonality
    Jeffrey Shaman
    College of Oceanic and Atmospheric Sciences, Oregon State University, Corvallis, OR 97331, USA
    Proc Natl Acad Sci U S A 106:3243-8. 2009
    ..This hypothesis can be further tested through future, additional laboratory, epidemiological and modeling studies...
  4. pmc Influenza virus transmission is dependent on relative humidity and temperature
    Anice C Lowen
    Department of Microbiology, Mount Sinai School of Medicine, New York, New York, USA
    PLoS Pathog 3:1470-6. 2007
    ..We provide direct, experimental evidence to support the role of weather conditions in the dynamics of influenza and thereby address a long-standing question fundamental to the understanding of influenza epidemiology and evolution...
  5. pmc Positional cloning of the wheat vernalization gene VRN1
    L Yan
    Department of Agronomy and Range Science, University of California, Davis 95616, USA
    Proc Natl Acad Sci U S A 100:6263-8. 2003
    ..A mutation in the promoter region of AP1 would result in the lack of recognition of the repressor and in a dominant spring growth habit...
  6. ncbi Tracking apex marine predator movements in a dynamic ocean
    B A Block
    Stanford University, Biology Department, Hopkins Marine Station, Pacific Grove, California 93950, USA
    Nature 475:86-90. 2011
    ..We identify critical habitats across multinational boundaries and show that top predators exploit their environment in predictable ways, providing the foundation for spatial management of large marine ecosystems...
  7. ncbi Seasonality and the dynamics of infectious diseases
    Sonia Altizer
    Institute of Ecology, University of Georgia, Athens, GA, USA
    Ecol Lett 9:467-84. 2006
    ..Finally, by focusing on well-studied examples of infectious diseases, we hope to highlight general insights that are relevant to other ecological interactions...
  8. ncbi Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis
    Michael F Holick
    Vitamin D, Skin, and Bone Research Laboratory, Section of Endocrinology, Diabetes, and Nutrition, Department of Medicine, Boston University School of Medicine, Boston, MA 02118 2394, USA
    Am J Clin Nutr 79:362-71. 2004
    ..The recommended adequate intakes for vitamin D are inadequate, and, in the absence of exposure to sunlight, a minimum of 1000 IU vitamin D/d is required to maintain a healthy concentration of 25(OH)D in the blood...
  9. ncbi Climate change and human health: present and future risks
    Anthony J McMichael
    National Centre for Epidemiology and Population Health, The Australian National University, Canberra 0200, Australia
    Lancet 367:859-69. 2006
    ..Evidence and anticipation of adverse health effects will strengthen the case for pre-emptive policies, and will also guide priorities for planned adaptive strategies...
  10. ncbi Arabidopsis, the Rosetta stone of flowering time?
    Gordon G Simpson
    Department of Cell and Developmental Biology, John Innes Centre, Norwich, NR4 7UH, UK
    Science 296:285-9. 2002
    ..This framework provides the basis to understand the evolution of different reproductive strategies and how floral pathways interact through seasonal progression...
  11. pmc Absolute humidity and the seasonal onset of influenza in the continental United States
    Jeffrey Shaman
    College of Oceanic and Atmospheric Sciences, Oregon State University, Corvallis, Oregon, United States of America
    PLoS Biol 8:e1000316. 2010
    ..These findings provide epidemiological support for the hypothesis that absolute humidity drives seasonal variations of influenza transmission in temperate regions...
  12. pmc Defining seasonal marine microbial community dynamics
    Jack A Gilbert
    Plymouth Marine Laboratory, Prospect Place, Plymouth, UK
    ISME J 6:298-308. 2012
    ..Interestingly, microbial association network analysis showed that correlations in abundance were stronger within bacterial taxa rather than between bacteria and eukaryotes, or between bacteria and environmental variables...
  13. pmc Influenza A (H1N1) 2009 antibodies in residents of New South Wales, Australia, after the first pandemic wave in the 2009 southern hemisphere winter
    Gwendolyn L Gilbert
    Centre for Infectious Diseases and Microbiology, Institute of Clinical Pathology and Medical Research, The University of Sydney, Sydney, New South Wales, Australia
    PLoS ONE 5:e12562. 2010
  14. ncbi Impact of climate change on marine pelagic phenology and trophic mismatch
    Martin Edwards
    Sir Alister Hardy Foundation for Ocean Science, The Laboratory, Citadel Hill, Plymouth PL1 2PB, UK
    Nature 430:881-4. 2004
  15. pmc Modeling the effects of weather and climate change on malaria transmission
    Paul Edward Parham
    Department of Infectious Disease Epidemiology, Grantham Institute for Climate Change, Imperial College London, London, United Kingdom
    Environ Health Perspect 118:620-6. 2010
  16. ncbi International study of temperature, heat and urban mortality: the 'ISOTHURM' project
    Anthony J McMichael
    National Centre for Epidemiology and Population Health, The Australian National University College of Medicine and Health Sciences, Canberra, Australia
    Int J Epidemiol 37:1121-31. 2008
    ..This study describes heat- and cold-related mortality in 12 urban populations in low- and middle-income countries, thereby extending knowledge of how diverse populations, in non-OECD countries, respond to temperature extremes...
  17. ncbi Spreading dead zones and consequences for marine ecosystems
    Robert J Diaz
    Virginia Institute of Marine Science, College of William and Mary, Gloucester Point, VA 23062, USA
    Science 321:926-9. 2008
    ..Dead zones have now been reported from more than 400 systems, affecting a total area of more than 245,000 square kilometers, and are probably a key stressor on marine ecosystems...
  18. pmc Association between climate variability and malaria epidemics in the East African highlands
    Guofa Zhou
    Department of Biological Sciences, State University of New York, Buffalo, NY 14260, USA
    Proc Natl Acad Sci U S A 101:2375-80. 2004
  19. ncbi Spatial and temporal heterogeneity of Anopheles mosquitoes and Plasmodium falciparum transmission along the Kenyan coast
    Charles M Mbogo
    Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute, Kilifi, Kenya
    Am J Trop Med Hyg 68:734-42. 2003
    ..The field-based estimate of entomologic parameters on a district level does not provide a sensitive indicator of transmission intensity in this study...
  20. pmc Continued decline of malaria in The Gambia with implications for elimination
    Serign J Ceesay
    Medical Research Council Laboratories, Fajara, Banjul, The Gambia
    PLoS ONE 5:e12242. 2010
    ..Scale up of interventions has since increased with support from the Global Fund and other donors...
  21. pmc Age-patterns of malaria vary with severity, transmission intensity and seasonality in sub-Saharan Africa: a systematic review and pooled analysis
    Ilona Carneiro
    Disease Control and Vector Biology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 5:e8988. 2010
    ..We have, therefore, undertaken a pooled analysis of existing data from multiple sites to enable a comprehensive overview of the age-patterns of malaria outcomes under different epidemiological conditions in sub-Saharan Africa...
  22. ncbi The wheat VRN2 gene is a flowering repressor down-regulated by vernalization
    Liuling Yan
    Department of Agronomy and Range Science, University of California, Davis, CA 95616, USA
    Science 303:1640-4. 2004
    ..Reduction of the RNA level of VRN2 by RNA interference accelerated the flowering time of transgenic winter-wheat plants by more than a month...
  23. pmc Temperature, temperature extremes, and mortality: a study of acclimatisation and effect modification in 50 US cities
    M Medina-Ramón
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02215, USA
    Occup Environ Med 64:827-33. 2007
    ..The authors examined the increase in mortality associated with hot and cold temperature in different locations, the determinants of the variability in effect estimates, and its implications for adaptation...
  24. pmc Respiratory viral infections among pediatric inpatients and outpatients in Taiwan from 1997 to 1999
    H P Tsai
    National Health Research Institutes Tainan Virology Laboratory for Diagnosis and Research, Department of Pathology, National Cheng Kung University Hospital, Tainan, Taiwan
    J Clin Microbiol 39:111-8. 2001
    ..These data expand our understanding of the etiology of acute respiratory tract viral infections among in- and outpatients in a subtropical country and may contribute to the prevention and control of viral respiratory tract infections...
  25. ncbi Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol
    Robert P Heaney
    Creighton University, Omaha, NE 68131, USA
    Am J Clin Nutr 77:204-10. 2003
    ..The cholecalciferol inputs required to achieve or maintain any given serum 25-hydroxycholecalciferol concentration are not known, particularly within ranges comparable to the probable physiologic supply of the vitamin...
  26. ncbi The effect of temperature on mortality in rural Bangladesh--a population-based time-series study
    Masahiro Hashizume
    Institute of Tropical Medicine, Nagasaki University, 1 12 4, Sakamoto, Nagasaki 852 8523, Japan
    Int J Epidemiol 38:1689-97. 2009
    ..However, few studies have examined temperature-mortality relationship in the rural areas of developing countries. In this study we therefore aimed to characterize the daily temperature-mortality relationships in rural Bangladesh...
  27. pmc Incidence, seasonality and mortality associated with influenza pneumonia in Thailand: 2005-2008
    James Mark Simmerman
    International Emerging Infections Program, Thailand Ministry of Public Health United States Centers for Disease Control Collaboration, Nonthaburi, Thailand
    PLoS ONE 4:e7776. 2009
    ..Prospective data from multiple years are needed to develop vaccine policy and treatment guidelines, and improve pandemic preparedness...
  28. ncbi Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial
    Kerrie M Sanders
    Department of Clinical and Biomedical Sciences, Barwon Health, University of Melbourne, Geelong, Victoria, Australia 3220
    JAMA 303:1815-22. 2010
    ..Improving vitamin D status may be an important modifiable risk factor to reduce falls and fractures; however, adherence to daily supplementation is typically poor...
  29. pmc Global influenza seasonality: reconciling patterns across temperate and tropical regions
    James Tamerius
    School of Geography and Development, University of Arizona, Tucson, Arizona, USA
    Environ Health Perspect 119:439-45. 2011
  30. pmc Characterizing the epidemiology of the 2009 influenza A/H1N1 pandemic in Mexico
    Gerardo Chowell
    Mathematical, Computational and Modeling Sciences Center, School of Human Evolution and Social Change, Arizona State University, Tempe, Arizona, United States of America
    PLoS Med 8:e1000436. 2011
    ..In this study we analyzed the epidemiological patterns of the pandemic during April-December 2009 in Mexico and evaluated the impact of nonmedical interventions, school cycles, and demographic factors on influenza transmission...
  31. pmc Effects of global climate on infectious disease: the cholera model
    Erin K Lipp
    Center of Marine Biotechnology, University of Maryland Biotechnology Institute, Baltimore, Maryland 21202, USA
    Clin Microbiol Rev 15:757-70. 2002
    ..First, the disease has a historical context linking it to specific seasons and biogeographical zones. In addition, the population dynamics of V...
  32. ncbi Heat effects on mortality in 15 European cities
    Michela Baccini
    Department of Statistics, University of Florence, Italy
    Epidemiology 19:711-9. 2008
    ..We report the associations between daily maximum apparent temperature and daily deaths during the warm season in 15 European cities...
  33. ncbi Influenza-associated hospitalizations in the United States
    William W Thompson
    Epidemiology and Surveillance Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    JAMA 292:1333-40. 2004
    ..Respiratory viral infections are responsible for a large number of hospitalizations in the United States each year...
  34. pmc Seasonal variation in host susceptibility and cycles of certain infectious diseases
    S F Dowell
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 7:369-74. 2001
    ..If such physiologic changes underlie human resistance to infectious diseases for large portions of the year and the changes can be identified and modified, the therapeutic and preventive implications may be considerable...
  35. ncbi Climate change and population declines in a long-distance migratory bird
    Christiaan Both
    Netherlands Institute of Ecology NIOO KNAW, PO Box 40, 6666ZG Heteren, The Netherlands
    Nature 441:81-3. 2006
    ..Mistiming as a result of climate change is probably a widespread phenomenon, and here we provide evidence that it can lead to population declines...
  36. ncbi The seasonal structure of microbial communities in the Western English Channel
    Jack A Gilbert
    Plymouth Marine Laboratory, Prospect Place, Plymouth, PL1 3DH, UK
    Environ Microbiol 11:3132-9. 2009
    ..There is also evidence for seasonal succession, primarily reflecting changes among dominant taxa. These changes in structure were significantly correlated to a combination of temperature, phosphate and silicate concentrations...
  37. pmc Predicting the epidemic sizes of influenza A/H1N1, A/H3N2, and B: a statistical method
    Edward Goldstein
    Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Med 8:e1001051. 2011
    ..We use publicly available US Centers for Disease Control (CDC) influenza surveillance data between 1997 and 2009 to study the temporal dynamics of influenza over this period...
  38. ncbi Viral respiratory infections in hospitalized and community control children in Alaska
    Rosalyn J Singleton
    Alaska Native Tribal Health Consortium, Anchorage, Alaska
    J Med Virol 82:1282-90. 2010
    ..Rhinovirus and adenovirus were detected in two-thirds of hospitalized children, but their frequent detection in control children made their role in respiratory hospitalization uncertain...
  39. ncbi Mapping the antigenic and genetic evolution of influenza virus
    Derek J Smith
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Science 305:371-6. 2004
    ..Further, this approach offers a route to predicting the relative success of emerging strains, which could be achieved by quantifying the combined effects of population level immune escape and viral fitness on strain evolution...
  40. ncbi Malaria early warnings based on seasonal climate forecasts from multi-model ensembles
    M C Thomson
    International Research Institute for Climate and Society IRI, The Earth Institute at Columbia University, New York, New York 10964 8000, USA
    Nature 439:576-9. 2006
    ..In years in which the forecast probability distribution is different from that of climatology, malaria decision-makers can use this information for improved resource allocation...
  41. ncbi Synchrony, waves, and spatial hierarchies in the spread of influenza
    Cecile Viboud
    Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
    Science 312:447-51. 2006
    ..Outbreaks show hierarchical spatial spread evidenced by higher pairwise synchrony between more populous states. Seasons with higher influenza mortality are associated with higher disease transmission and more rapid spread than are ..
  42. pmc Incidence of influenza-like illness and severe acute respiratory infection during three influenza seasons in Bangladesh, 2008-2010
    Eduardo Azziz-Baumgartner
    International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Ahmed, Sarani, Mohakhali, Dhaka 1212, Bangladesh
    Bull World Health Organ 90:12-9. 2012
    ..To determine how much influenza contributes to severe acute respiratory illness (SARI), a leading cause of death in children, among people of all ages in Bangladesh...
  43. ncbi The use of 'altitude' in ecological research
    Christian Korner
    Institute of Botany, University of Basel, Schönbeinstrasse 6, Basel, CH 4056, Switzerland
    Trends Ecol Evol 22:569-74. 2007
    ..The confounding of the first category by the latter has introduced confusion in the scientific literature on altitude phenomena...
  44. pmc Absolute humidity and pandemic versus epidemic influenza
    Jeffrey Shaman
    Oregon State University, Corvallis, 97331, USA
    Am J Epidemiol 173:127-35. 2011
    ..These findings suggest that the timing of pandemic influenza outbreaks is controlled by a combination of absolute humidity conditions, levels of susceptibility, and changes in population-mixing and contact rates...
  45. ncbi Estimating the impact of school closure on influenza transmission from Sentinel data
    Simon Cauchemez
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Diseases Epidemiology, Imperial College London, Norfolk Place, London W2 1PG, UK
    Nature 452:750-4. 2008
    ..The impact of school closure would be reduced if it proved difficult to maintain low contact rates among children for a prolonged period...
  46. ncbi Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors
    Elina Hypponen
    Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, United Kingdom
    Am J Clin Nutr 85:860-8. 2007
    ..Increased awareness of the importance of vitamin D to health has led to concerns about the prevalence of hypovitaminosis D in many parts of the world...
  47. pmc A weather-driven model of malaria transmission
    Moshe B Hoshen
    Virtual Population Laboratory, Department of Physics, University of Liverpool, Liverpool L69 7ZE, UK
    Malar J 3:32. 2004
    ..Climate is a major driving force behind malaria transmission and climate data are often used to account for the spatial, seasonal and interannual variation in malaria transmission...
  48. pmc Changes in the genetic structure of Aedes aegypti (Diptera: Culicidae) populations in Queensland, Australia, across two seasons: implications for potential mosquito releases
    N M Endersby
    Centre for Environmental Stress and Adaptation Research, Department of Genetics, Bio21 Institute, The University of Melbourne, Victoria 3010, Australia
    J Med Entomol 48:999-1007. 2011
    ..aegypti in proposed release areas, as well as rates of gene flow among populations in the wet and dry tropical seasons. Mosquitoes from northern Queensland were screened with genetic markers to find an optimal locality for release ..
  49. ncbi Cholera dynamics and El Niño-Southern Oscillation
    M Pascual
    Center of Marine Biotechnology, University of Maryland Biotechnology Institute, 701 East Pratt Street, Suite 236, Columbus Center, Baltimore, MD 21202, USA
    Science 289:1766-9. 2000
    ..Cholera patterns are linked to the previously described changes in the atmospheric circulation of south Asia and, consistent with these changes, to regional temperature anomalies...
  50. ncbi CO/FT regulatory module controls timing of flowering and seasonal growth cessation in trees
    Henrik Böhlenius
    Umea Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, S 90183 Umeå, Sweden
    Science 312:1040-3. 2006
    ..This regulatory mechanism can explain the ecogenetic variation in a highly adaptive trait: the critical daylength for growth cessation displayed by aspen trees sampled across a latitudinal gradient spanning northern Europe...
  51. ncbi Coupling 16S-ITS rDNA clone libraries and automated ribosomal intergenic spacer analysis to show marine microbial diversity: development and application to a time series
    Mark V Brown
    Department of Biological Science and Wrigley Institute for Marine Studies, University of Southern California, 3616 Trousdale Parkway, AHF B4, Los Angeles, CA 90089, USA
    Environ Microbiol 7:1466-79. 2005
    ..16S-ITS data allowed high-resolution identification of organisms by ITS sequence analysis, and examination of microdiversity...
  52. pmc Rift Valley fever during rainy seasons, Madagascar, 2008 and 2009
    Soa Fy Andriamandimby
    Institut Pasteur, Antananarivo, Madagascar
    Emerg Infect Dis 16:963-70. 2010
    During 2 successive rainy seasons, January 2008 through May 2008 and November 2008 through March 2009, Rift Valley fever virus (RVFV) caused outbreaks in Madagascar...
  53. ncbi Mortality benefits of influenza vaccination in elderly people: an ongoing controversy
    Lone Simonsen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Lancet Infect Dis 7:658-66. 2007
    ..The remaining evidence base is currently insufficient to indicate the magnitude of the mortality benefit, if any, that elderly people derive from the vaccination programme...
  54. ncbi Impact of influenza vaccination on seasonal mortality in the US elderly population
    Lone Simonsen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 6613, USA
    Arch Intern Med 165:265-72. 2005
    ..We tried to reconcile these conflicting findings by adjusting excess mortality estimates for aging and increased circulation of influenza A(H3N2) viruses...
  55. ncbi Long-term decline in krill stock and increase in salps within the Southern Ocean
    Angus Atkinson
    British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge CB3 OET, UK aat bas ac uk
    Nature 432:100-3. 2004
    ..As krill densities decreased last century, salps appear to have increased in the southern part of their range. These changes have had profound effects within the Southern Ocean food web...
  56. ncbi Thyrotrophin in the pars tuberalis triggers photoperiodic response
    Nobuhiro Nakao
    Division of Biomodelling, Graduate School of Bioagricultural Sciences, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8601, Japan
    Nature 452:317-22. 2008
    ..Increased TSH in the pars tuberalis therefore seems to trigger long-day photoinduced seasonal breeding...
  57. ncbi Are meteorological parameters associated with acute respiratory tract infections?
    Jean Baptist du Prel
    Kinderklinik, Paediatrische Infektiologie and Zentrum Praeventive Paediatrie, Universitaetsmedizin, Johannes Gutenberg Universitaet, Mainz, Germany
    Clin Infect Dis 49:861-8. 2009
    ..Aiming at better predictions of the seasonal activity of ARI pathogens, we investigated the influence of climate on hospitalizations for ARIs...
  58. ncbi Climate-driven increases in global terrestrial net primary production from 1982 to 1999
    Ramakrishna R Nemani
    School of Forestry, University of Montana, Missoula, MT 59801, USA
    Science 300:1560-3. 2003
    ..The largest increase was in tropical ecosystems. Amazon rain forests accounted for 42% of the global increase in net primary production, owing mainly to decreased cloud cover and the resulting increase in solar radiation...
  59. ncbi Seasonal transmission of bluetongue virus by Culicoides sonorensis (Diptera: Ceratopogonidae) at a southern California dairy and evaluation of vectorial capacity as a predictor of bluetongue virus transmission
    A C Gerry
    Department of Entomology, University of California, Riverside 92521, USA
    J Med Entomol 38:197-209. 2001
    ..The utility of vectorial capacity and its component variables is discussed for this system...
  60. ncbi Large-scale forest girdling shows that current photosynthesis drives soil respiration
    P Högberg
    Department of Forest Ecology, SLU, Umea, Sweden
    Nature 411:789-92. 2001
    ..Our results indicate that models of soil respiration should incorporate measures of photosynthesis and of seasonal patterns of photosynthate allocation to roots...
  61. pmc Multiplicity of Plasmodium falciparum infection in asymptomatic children in Senegal: relation to transmission, age and erythrocyte variants
    Manijeh Vafa
    Department of Immunology, Stockholm University, S 106 91 Stockholm, Sweden
    Malar J 7:17. 2008
    ..This study aimed to examine the MOI in asymptomatic children between two and ten years of age and to relate it to erythrocyte variants, clinical attacks, transmission levels and other parasitological indexes...
  62. ncbi Diversity and productivity in a long-term grassland experiment
    D Tilman
    Department of Ecology, Evolution and Behavior, University of Minnesota, St Paul, MN 55108, USA
    Science 294:843-5. 2001
  63. pmc Identifying the most productive breeding sites for malaria mosquitoes in The Gambia
    Ulrike Fillinger
    Disease Control and Vector Biology Unit, London School of Hygiene and Tropical Medicine, London, UK
    Malar J 8:62. 2009
    ..This study aimed to determine the characteristics of larval habitats most frequently and most densely populated by anopheline larvae and to estimate the numbers of adults produced in different habitats...
  64. ncbi Rapid changes in flowering time in British plants
    A H Fitter
    Department of Biology, University of York, York YO10 5DD, UK
    Science 296:1689-91. 2002
    ..Annuals are more likely to flower early than congeneric perennials, and insect-pollinated species more than wind-pollinated ones...
  65. ncbi Geographic expansion of dengue: the impact of international travel
    Annelies Wilder-Smith
    Department of Medicine, Travelers Screening and Vaccination Clinic, National University Hospital of Singapore, National University of Singapore, 5, Lower Kent Ridge, Singapore 119074
    Med Clin North Am 92:1377-90, x. 2008
    ..Epidemics of dengue, their seasonality, and oscillations over time are reflected by the epidemiology of dengue in travelers. Sentinel surveillance of travelers could augment existing national public health surveillance systems...
  66. pmc Excess winter mortality in Europe: a cross country analysis identifying key risk factors
    J D Healy
    Department of Environmental Studies, University College Dublin, Richview Campus, Dublin 14, Ireland
    J Epidemiol Community Health 57:784-9. 2003
    ..Multiple time series data on a variety of risk factors are analysed against seasonal-mortality patterns in 14 European countries to identify key relations Subjects and setting: Excess winter deaths (all causes), 1988-97, EU-14...
  67. ncbi Cold and heat waves in the United States
    A G Barnett
    School of Public Health and Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, Australia
    Environ Res 112:218-24. 2012
    ..Cold or heat waves earlier in the cool or warm season may be more dangerous because of a build up in the susceptible pool or a lack of preparedness for extreme temperatures...
  68. pmc Genome-wide transcriptional analysis of grapevine berry ripening reveals a set of genes similarly modulated during three seasons and the occurrence of an oxidative burst at vèraison
    Stefania Pilati
    Department of Genetics and Molecular Biology IASMA Research Center, Via E, Mach 1, 38010 S, Michele a Adige TN, Italy
    BMC Genomics 8:428. 2007
    ..Despite this relevance, little is known about the transcriptional changes and the regulatory circuits underlying the biochemical and physical changes occurring during berry development...
  69. pmc Serologic markers for detecting malaria in areas of low endemicity, Somalia, 2008
    Teun Bousema
    London School of Hygiene and Tropical Medicine, London, UK
    Emerg Infect Dis 16:392-9. 2010 microscopy in cross-sectional surveys of samples from persons during the dry (0/1,178) and wet (0/1,128) seasons. Antibody responses against P. falciparum or P. vivax were detected in 17.9% (179/1,001) and 19...
  70. ncbi Vernalization requires epigenetic silencing of FLC by histone methylation
    Ruth Bastow
    Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, UK
    Nature 427:164-7. 2004
    ..The epigenetic memory of winter is thus mediated by a 'histone code' that specifies a silent chromatin state conserved between animals and plants...
  71. pmc The association between extreme precipitation and waterborne disease outbreaks in the United States, 1948-1994
    F C Curriero
    Department of Biostatistics, Johns Hopkins University, Baltimore, MD, USA
    Am J Public Health 91:1194-9. 2001
    ..CONCLUSIONS: The statistically significant association found between rainfall and disease in the United States is important for water managers, public health officials, and risk assessors of future climate change...
  72. ncbi Evaluation of the antibody response to Anopheles salivary antigens as a potential marker of risk of malaria
    Franck Remoue
    Institut de recherche pour le developpement IRD, UR24 Epidémiologie et Prévention Unit, Centre IRD de Hann, BP 1386, Dakar, Senegal
    Trans R Soc Trop Med Hyg 100:363-70. 2006
    ..These results suggest that evaluation of antisalivary Ab responses could be a useful approach for identifying a marker for the risk of malaria transmission...
  73. ncbi Pyrosequencing reveals contrasting seasonal dynamics of taxa within Baltic Sea bacterioplankton communities
    Anders F Andersson
    Limnology Department of Ecology and Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
    ISME J 4:171-81. 2010
  74. pmc School closure and mitigation of pandemic (H1N1) 2009, Hong Kong
    Joseph T Wu
    The University of Hong Kong School of Public Health, Hong Kong Special Administrative Region, People s Republic of China
    Emerg Infect Dis 16:538-41. 2010
    ..Secondary schools closed for summer vacation shortly afterwards. By fitting a model of reporting and transmission to case data, we estimated that transmission was reduced approximately 25% when secondary schools closed...
  75. pmc Impact of intermittent preventive treatment with sulphadoxine-pyrimethamine targeting the transmission season on the incidence of clinical malaria in children in Mali
    Alassane Dicko
    Malaria Research and Training Center, Departments of Epidemiology of Parasitic Diseases, Faculty of Medicine Pharmacy and Dentistry, University of Bamako, P O Box 1805, Bamako, Mali
    Malar J 7:123. 2008
    ..However in most areas malaria morbidity and mortality remain high in older children...
  76. pmc Disparities by race in heat-related mortality in four US cities: the role of air conditioning prevalence
    Marie S O'Neill
    The Robert Wood Johnson Health and Society Scholars Program, Center for Social Epidemiology and Population Health, University of Michigan, Ann Arbor, MI 48104 2548, USA
    J Urban Health 82:191-7. 2005
    ..Central AC prevalence explained some of the differences in heat effects by race, but room-unit AC did not. Efforts to reduce disparities in heat-related mortality should consider access to AC...
  77. ncbi Large deletions within the first intron in VRN-1 are associated with spring growth habit in barley and wheat
    Daolin Fu
    Department of Plant Sciences, University of California, One Shields Av, Davis, CA 95616, USA
    Mol Genet Genomics 273:54-65. 2005
    ..Epistatic interactions between VRN-H2 and the VRN-H1 allele with the intron 1 deletion suggest that the deleted region may include a recognition site for the flowering repression mediated by the product of the VRN-H2 gene of barley...
  78. ncbi Epidemiology and seasonality of respiratory tract virus infections in the tropics
    Lynette Pei Chi Shek
    Department of Paediatrics, National University of Singapore, Lower Kent Ridge Road, Singapore 119074
    Paediatr Respir Rev 4:105-11. 2003
    ..Despite the absence of a winter season, consistent seasons of infection, albeit less distinct, have been observed...
  79. pmc Modelling the global constraints of temperature on transmission of Plasmodium falciparum and P. vivax
    Peter W Gething
    Spatial Ecology and Epidemiology Group, Department of Zoology, University of Oxford, Oxford, UK
    Parasit Vectors 4:92. 2011
  80. ncbi Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988-1994
    Shanna Nesby-O'Dell
    Division of Nutrition and Physical Activity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta 30341 3717, USA
    Am J Clin Nutr 76:187-92. 2002
    ..African American women are at higher risk of vitamin D deficiency than are white women, but few studies have examined determinants of hypovitaminosis D in this population...
  81. pmc Malaria in the African highlands: past, present and future
    S W Lindsay
    Department of Biological Sciences, University of Durham, England
    Bull World Health Organ 76:33-45. 1998
    ..We further recommend that a regional modelling approach should be adopted to assess the extent and severity of this problem and help improve disease surveillance and the quality of health care delivered in this unstable ecosystem...
  82. ncbi Mortality displacement of heat-related deaths: a comparison of Delhi, São Paulo, and London
    Shakoor Hajat
    London School of Hygiene and Tropical Medicine, United Kingdom
    Epidemiology 16:613-20. 2005
    ..We compare the extent to which short-term mortality displacement can explain heat deaths in Delhi, São Paulo, and London given contrasting demographic and health profiles...
  83. ncbi The effect of season and weather on physical activity: a systematic review
    P Tucker
    Faculty of Health Sciences, University of Western Ontario, Ontario, Canada
    Public Health 121:909-22. 2007
    ..This study reviewed previous studies to explore the effect of season, and consequently weather, on levels of physical activity...
  84. pmc Seasonal influenza vaccine and protection against pandemic (H1N1) 2009-associated illness among US military personnel
    Matthew C Johns
    Division of GEIS Operations, Armed Forces Health Surveillance Center, Silver Spring, Maryland, United States of America
    PLoS ONE 5:e10722. 2010
    ..A novel A/H1N1 virus is the cause of the present influenza pandemic; vaccination is a key countermeasure, however, few data assessing prior seasonal vaccine effectiveness (VE) against the pandemic strain of H1N1 (pH1N1) virus are available...
  85. ncbi Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets
    Vincent J Munster
    National Influenza Center and Department of Virology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands
    Science 325:481-3. 2009
    ..These data suggest that the 2009 A(H1N1) influenza virus has the ability to persist in the human population, potentially with more severe clinical consequences...
  86. ncbi Challenging claims in the study of migratory birds and climate change
    Endre Knudsen
    Centre for Ecological and Evolutionary Synthesis CEES, Department of Biology, University of Oslo, Norway
    Biol Rev Camb Philos Soc 86:928-46. 2011
    ..A proper integration across biological disciplines seems essential for the field's transition from affirming patterns to understanding mechanisms and making robust predictions regarding future consequences of shifting phenologies...
  87. pmc Excess cardiovascular mortality associated with cold spells in the Czech Republic
    Jan Kysely
    Institute of Atmospheric Physics, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    BMC Public Health 9:19. 2009
    ..No comprehensive study on cold-related mortality in central Europe has been carried out despite the fact that cold air invasions are more frequent and severe in this region than in western and southern Europe...
  88. pmc Has the impact of heat waves on mortality changed in France since the European heat wave of summer 2003? A study of the 2006 heat wave
    A Fouillet
    INSERM, U754, IFR69, Universite Paris Sud 11, Epidémiologie Environnementale des Cancers, Villejuif, France
    Int J Epidemiol 37:309-17. 2008
    ..In order to evaluate the effectiveness of those measures, the observed excess mortality during the 2006 heat wave was compared to the expected excess mortality...
  89. ncbi Net carbon dioxide losses of northern ecosystems in response to autumn warming
    Shilong Piao
    LSCE, UMR CEA CNRS, Bâtiment 709, CE, L Orme des Merisiers, F 91191 Gif sur Yvette, France
    Nature 451:49-52. 2008
    ..If future autumn warming occurs at a faster rate than in spring, the ability of northern ecosystems to sequester carbon may be diminished earlier than previously suggested...
  90. ncbi Mapping the basic reproduction number (R₀) for vector-borne diseases: a case study on bluetongue virus
    N A Hartemink
    Theoretical Epidemiology, Veterinary Medicine, Utrecht, The Netherlands
    Epidemics 1:153-61. 2009
  91. ncbi Spatial and temporal variations of malaria epidemic risk in Ethiopia: factors involved and implications
    Tarekegn Abose Abeku
    Department of Public Health, Erasmus MC, University Medical Centre, PO Box 1738, 3000 DR, Rotterdam, The Netherlands
    Acta Trop 87:331-40. 2003
    ..A period of low incidence during previous transmission seasons might have aggravated the events, possibly due to low level of immunity in affected populations...
  92. ncbi Photoperiodic control of seasonality in birds
    A Dawson
    Centre for Ecology and Hydrology, Huntingdon, Cambridgeshire, UK
    J Biol Rhythms 16:365-80. 2001
    ..Avian breeding seasons tend to be of shorter duration and more asymmetric with respect to changes in photoperiod...
  93. ncbi Global application of stable hydrogen and oxygen isotopes to wildlife forensics
    Gabriel J Bowen
    Department of Biology, University of Utah, 257 South 1400 East, Salt Lake City, UT 84112, USA
    Oecologia 143:337-48. 2005
    ..These maps are available in GIS format at
  94. ncbi An outbreak of serotype 1 Streptococcus pneumoniae meningitis in northern Ghana with features that are characteristic of Neisseria meningitidis meningitis epidemics
    Julia Leimkugel
    Swiss Tropical Institute, Basel, Switzerland
    J Infect Dis 192:192-9. 2005
    ..These epidemics are generally caused by Neisseria meningitidis, an organism that is considered to be uniquely capable of causing meningitis epidemics...
  95. pmc Space-time clustering of childhood malaria at the household level: a dynamic cohort in a Mali village
    Jean Gaudart
    Medical Statistics and Informatics Research Team, LIF UMR 6166 CNRS Aix Marseille University, Faculty of Medicine, 27 Bd Jean Moulin 13385 Marseille Cedex 05, France
    BMC Public Health 6:286. 2006
    ..The aim of this study was to identify, spatially and temporally, high-risk zones of malaria, at the household level (resolution of 1 to 3 m)...
  96. ncbi The evolution of epidemic influenza
    Martha I Nelson
    Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Nat Rev Genet 8:196-205. 2007
  97. ncbi The prevalence of vitamin D inadequacy amongst women with osteoporosis: an international epidemiological investigation
    P Lips
    Vrije Universiteit Medical Center, Amsterdam, The Netherlands, and Nottingham City Hospital, David Evans Medical Research Centre, UK
    J Intern Med 260:245-54. 2006
    ..A high prevalence of inadequacy has been reported in many studies but the prevalence of inadequacy amongst women with osteoporosis in different regions of the world has not been well characterized...
  98. pmc Seasonality of rotavirus disease in the tropics: a systematic review and meta-analysis
    Karen Levy
    Department of Environmental Science, University of California, Berkeley, USA
    Int J Epidemiol 38:1487-96. 2009
    ..We present a systematic review and meta-analysis on the seasonal epidemiology of rotavirus in the tropics, including 26 studies reporting continuous monthly rotavirus incidence for which corresponding climatological data was available...
  99. ncbi Inapparent infections and cholera dynamics
    Aaron A King
    Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Nature 454:877-80. 2008
    ..Our experience suggests that the confrontation of time-series data with mechanistic models is likely to revise our understanding of the ecology of many infectious diseases...
  100. pmc Seasonal transmission potential and activity peaks of the new influenza A(H1N1): a Monte Carlo likelihood analysis based on human mobility
    Duygu Balcan
    Center for Complex Networks and Systems Research, School of Informatics and Computing, Indiana University, Bloomington, IN, USA
    BMC Med 7:45. 2009
  101. ncbi Nosema ceranae in European honey bees (Apis mellifera)
    Ingemar Fries
    Department of Ecology, Swedish University of Agricultural Sciences, Box 7044, 75007 Uppsala, Sweden
    J Invertebr Pathol 103:S73-9. 2010
    ..The recent advancements in N. ceranae genetics, with a draft assembly of the N. ceranae genome available, are discussed and the need for increased research on the impacts of this parasite on European honey bees is emphasized...

Research Grants64

  1. The influence of air pollution mixtures on biomarkers of airway oxidative stress
    Roby Greenwald; Fiscal Year: 2013
    ..The candidate will conduct air quality sampling during seasons of both high and low ozone and will also conduct sampling during indoor physical activities as a reference...
  2. Antiarrhythmic Mechanisms in the Hearts of Hibernating Mammals
    Lai Hua Xie; Fiscal Year: 2013
  3. Photoperiod Brain and Behavior
    Randy J Nelson; Fiscal Year: 2012
  4. Clinical Impact of Human Coronaviruses and Viral Diversity
    Geoffrey J Gorse; Fiscal Year: 2012
    ..of such infections on this population will be assessed in this four year study in terms of frequency in different seasons, the characteristics and severity of the associated illness and resultant use of healthcare resources...
  5. Effects of Maternal Influenza Immunization: A Field Trial in Guatemala'
    Saad B Omer; Fiscal Year: 2010
    ..The enrollment will be conducted over three years;incorporating three influenza seasons. We will evaluate efficacy and safety of maternal immunization with inactivated influenza vaccine in a) pregnant ..
  6. Maternal Stress, Obesity, and Influenza Virus Vaccine Immunogenicity in Pregnancy
    LISA MICHELLE CHRISTIAN; Fiscal Year: 2013
    ..Data will be collected across three influenza seasons. In each season, 60 women will be assessed;30 obese and 30 non-obese who will be similar in age, race, parity, ..
  7. Ecology of Infectious Diseases (EID)-Immune Landscapes of Human Influenza in Hous
    Derek Cummings; Fiscal Year: 2011
    ..into households than adults, and can we predict that some geographical areas might be harder hit in future seasons using serological data from past seasons? The mathematical models used to help answer these questions will vary ..
  8. Seasonality of Mood: A Genome-Wide Association Study in the Old Order Amish
    Teodor T Postolache; Fiscal Year: 2010
    ..The study will be the first genomic study on seasonality of mood, and first seasonality study in the US in a population not using electric light. ..
  9. Gut micro biota in patients with multiple sclerosis
    Howard L Weiner; Fiscal Year: 2012
    ..It applies for the first time an important newly developing technology to gain potential basic insights into an autoimmune disease whose underlying pathogenesis remains unknown. ..
  10. Ecological and genetic determinants of malaria transmitting behaviors in the Afri
    Gregory C Lanzaro; Fiscal Year: 2013
    ..will be intensively collected from four villages in the Kilombero Valley of Tanzania during the wet and dry seasons to determine the association between their feeding and resting phenotype and environmental factors that vary ..
  11. Using genomics to understand physiologic water conservation in desert rodents
    MATTHEW MACMANES; Fiscal Year: 2013
    ..will be subjected to whole genome profiling (Illumina sequencing) and gene expression will be compared between seasons. I will compare gene expression in dry versus wet seasons in all species...
  12. Environmental filters and medically important container mosquitoes
    Donald A Yee; Fiscal Year: 2011
    ..the role of environmental factors in explaining patterns of container mosquitoes across spatial scales and seasons. We will sample natural containers to test the hypothesis that local and regional spatial and temporal variation ..
  13. Genomic Mechanisms of Chromosomal Rearrangements in Drosophila Pseudoobscura
    Stephen W Schaeffer; Fiscal Year: 2013
    ..The gene arrangement frequencies cycle with the seasons and show altitudinal clines...
  14. West Nile Virus: Epidemiology and Mosquito Competence
    Alan D T Barrett; Fiscal Year: 2010
    ..S. during the 2006-2011 transmission seasons;3. Investigate the mechanism of attenuation of neuroinvasiveness of mouse attenuated WNV isolates;4...
  15. Differential Provider Interactions and Ethnic Disparities in Influenza Vaccinatio
    KATHERINE MARIE HARRIS; Fiscal Year: 2011
    ..recently collected survey data on influenza vaccine uptake during the 2007-08 and 2008-09 influenza vaccination seasons, influenza-related beliefs and attitudes, and interactions with health care providers among a nationally ..
  16. A longitudinal Study of CA-MRSA Nasal Colonization in College Sports Participants
    Clarence Buddy Creech; Fiscal Year: 2010
    ..aureus and CA-MRSA in a cohort of healthy sports team participants during the course of two seasons;2) to define the frequency of clinical staphylococcal infections with CA-MRSA and methicillin-susceptible S...
  17. Molecular Mechanism of Photoperiodic Time Measurement
    Takato Imaizumi; Fiscal Year: 2013
  18. Epidemiology and modeling of the population dynamics of influenza and antimicrobi
    Edward Goldstein; Fiscal Year: 2013
    ..J. Wallinga of RIVM, the Netherlands) 3. Assessing the potential scope of emerging influenza seasons and the utility of implementing various control measures, such as the usage of antiviral drugs, using ..
  19. Impact of seasonality and vector control on population structure of P.falciparum
    Mercedes Pascual; Fiscal Year: 2013
    ..3): The quantitative description of var gene diversity and of var repertoires in wet and dry seasons, as well as across a major vector control intervention using indoor residual spraying (IRS), in comparison to ..
  20. On the Edge: Dengue and Climate
    Kacey C Ernst; Fiscal Year: 2013
    ..aegypti during four mosquito seasons. We expect that cities with extremely dry and hot conditions will have younger Ae. aegypti populations...
  21. Vitamin D Insufficiency in Pre- and Early Adolescent Children
    Kumaravel Rajakumar; Fiscal Year: 2011
  22. Development of a Universal Influenza Seasonal Vaccine
    David B Weiner; Fiscal Year: 2013
    ..The current strategy based on waiting to identify each seasons new strains and then building a matching vaccine based mostly on egg production is not ideal...
  23. Annual Estimates of Influenza Vaccine Effectiveness for Preventing Laboratory-Con
    Arnold S Monto; Fiscal Year: 2010
    ..season, with complete data available for summary analyses and publication by September following annual influenza seasons. Our secondary objective (5) is to recruit, vaccinate and collect paired pre- and post-vaccination blood ..
    Gregory Mertz; Fiscal Year: 2009
    ..viral load in rodent blood, tissue, and urine in the winter (low transmission) and spring (high transmission) seasons. Finally, serial serosurveys of at-risk human populations in Panama will quantify the impact on human infection ..
  25. The melanopsin-driven pupillary light reflex in seasonal affective disorder
    Kathryn A Roecklein; Fiscal Year: 2013
    ..2) To determine if individuals with SAD vary across the seasons on the PIPR in comparison to controls...
  26. On the Edge: Aedes aegypti dynamics on the boundary of its natural range.
    Kacey C Ernst; Fiscal Year: 2011
    ..aegypti during four mosquito seasons. We expect that cities with extremely dry and hot conditions will have younger Ae. aegypti populations...
  27. Engineered virus-like nanoparticles targeting immunity needed for pan flu vaccine
    Allen G Harmsen; Fiscal Year: 2013
    ..The goal of this proposal is to integrate these two antigens (csHA and NP) with a highly engineer-able nano- platform to elicit protective immune responses in an effort aimed at the development of a universal influenza vaccine. ..
  28. Vulnerability of the Adolescent Brain to Organophosphorus Pesticides
    Diane S Rohlman; Fiscal Year: 2013
    ..Some deficits may persist beyond the spray season or after repeated summer spray seasons. A biologically- based exposure assessment will incorporate levels of urinary metabolites of chlorpyrifos and ..
  29. Translational Research: From Mechanisms of Influenza Transmission to Prevention
    Donald Kirby Milton; Fiscal Year: 2010
    ..infectious respiratory droplets in a study of 220 naturally occurring seasonal influenza cases over two influenza seasons. We will collect respiratory droplets shed by participants while breathing normally, talking, and spontaneously ..
  30. Contact among Utah School-aged Populations (CUSP)
    Matthew H Samore; Fiscal Year: 2012
    ..A subset of the school setting respondents will be recruited to participate during all four seasons. The quantitative assessment tools used to collect contact and mixing data are surveys, self-diaries, and ..
  31. Impact of climate change on mosquito-borne arbovirus transmission
    C M Barker; Fiscal Year: 2011
    ..will expand virus distributions in time and space, enhance vernal amplification rates and extend transmission seasons. Public health intervention currently focuses on mosquito control, and our research will help health planners ..
  32. The Movement of Influenza Virus In Human Population
    Katherine A Poehling; Fiscal Year: 2013
    ..In Specific Aim 1 we will track the appearance of influenza A and B in adults and children over five consecutive seasons to define patterns of virus spread within human populations, and test the hypothesis that the virus moves from ..
  33. The effect of the 1918 influenza pandemic on seasonal influenza in the U.S.
    BIANCA MALCOLM; Fiscal Year: 2010 also understand how this great event might have affected the timing and spread of Influenza in non-pandemic seasons. This knowledge could inform targeted prevention strategies for a future pandemic...
  34. Enhanced Surveillance: New Vaccine Preventable Diseases
    ..Influenza vaccine effectiveness will evaluated for the 2003-2004 and 2004-2005 influenza seasons using a case cohort design...
  35. Climate Change Impacts on Power Plant Emissions, Air Quality and Health in the US
    JONATHAN ALAN PATZ; Fiscal Year: 2012
    ..emissions scenario of the IPCC;2) To model climate change impacts on the demand for electricity during summer seasons and determine spatially explicit emissions from electric power plants;and 3) To geographically locate and ..
  36. A Randomized Controlled Trial of an Adolescent IPV/SA Perpetration Prevention Pro
    Elizabeth Miller; Fiscal Year: 2011
    ..intervention and control site student athletes entering grades 9 through 11 at the start of each of three sports seasons across Year 1 (Time 1)...
  37. Adaptation of circadian responses to light treatment
    Jeanne F Duffy; Fiscal Year: 2010
    ..The understanding of the effects of prior photic history could help explain the ability of the circadian system to adapt to changes in natural outside light intensities across the seasons and at different latitudes.
  38. Rapid Pesticide Exposure Analysis Using Surface-Enhanced Raman Spectroscopy
    Kevin M Spencer; Fiscal Year: 2011
    ..preliminary demonstration is for the detection of pesticides in the air surrounding farmworkers during harvesting seasons and on surfaces of farmworker dwellings, and of pesticide metabolites in farmworker urine samples...
  39. Maryland Emerging Infections Program - PPACA
    David Blythe; Fiscal Year: 2011 emerging infectious disease threats, as was demonstrated during the 2003-2004 and subsequent influenza seasons. Through this application, the MD EIP is requesting funding to support: (1) overall program infrastructure;(2) ..
    Erica Dawson; Fiscal Year: 2009
    ..with initial samples will be validated in a blind study of 300+ patient samples acquired over at least two flu seasons by a variety of sampling methods, including nasal swab, nasal wash, and nasopharyngeal aspiration...
  41. The nasopharyngeal microbiome and respiratory disease in African children
    HEATHER JOY ZAR; Fiscal Year: 2013
    ..By focusing on training and ensuring that the complete pipeline (from sequence generation to final association analysis) is performed in South Africa we aim to build independent and sustainable capacity in this field. ..
  42. Impact of Seasonal Variation in Hematocrit, NOx & ET-1 on Vascular Reactivity
    Deidre Wipke Tevis; Fiscal Year: 2009
  43. Echinacea: Standardized Product & Supply Provision
    Xiping Wang; Fiscal Year: 2004
    ..addressed: Echinacea seeds will be tested and identified for purity, then germinated and cultivated at different seasons/soil/field conditions, and morphologic, organoleptic, chromosome/DNA, and microscopic characteristics will be ..
  44. Establishing Therapeutic Efficacy in Frontotemporal Degeneration
    Howard J Rosen; Fiscal Year: 2013
    ..for Familial Frontotemporal Degeneration (FTD)" conference, scheduled for November 14-16, 2013 at the Four Seasons Hotel in San Francisco, CA...
    Laura Punnett; Fiscal Year: 1990
    ..Additional observations will be made regarding specific ergonomic features of selected jobs at four occasions during the year corresponding to seasonal changes in garment styles under construction...
    RICK KELSEY; Fiscal Year: 1992
    ..Cultural techniques developed from this research would significantly contribute to a management system that could increase the supply of taxol without sacrificing wild trees...
    William Hrushesky; Fiscal Year: 1992
    PEDRO PIEDRA; Fiscal Year: 2007
    ..dose of CAIV-T in children was associated with significant protection that lasted through at least two influenza seasons, and 3) CAIV-T was safe and not associated with an increase in health care utilization...
    JEFFREY LUCAS; Fiscal Year: 2002
    ..An understanding of the adaptive significance of the suite of traits that cycle annually in natural systems will give us a unique insight into this important component of these seasonal disorders. ..
  50. Dietary Glycemic Load, Body Weight, and Blood Lipids
    Yunsheng Ma; Fiscal Year: 2005
    ..We will use dietary data collected from the Seasonal Variation in Blood Cholesterol Levels (SEASONS) (NHLBI: R01-HL52745) (1. Ockene - P.I...
  51. Ecological Genomics of Anopheles gambiae
    Nora Besansky; Fiscal Year: 2009
    ..gambiae: arid seasons and zones subject to irrigation for agriculture. It has been assumed that the arid-adapted incipient species (A...
  52. The Changing Epidemiology of Acute Gastroenteritis
    Sheila Nolan; Fiscal Year: 2009
    ..Hospital of Philadelphia's (CHOP) large practice-based research network over the first 2 consecutive RV seasons following the introduction of RW. The cohort is estimated to be approximately 60,000 patients...
    Laura Kramer; Fiscal Year: 1999
    ..In seasons when mosquitoes are active, SLE virus is maintained in enzootic cycle involving wild birds and mosquito vectors...
    Alfred Rimm; Fiscal Year: 1990
    ..In addition, the description of the variation in person, place, and time may aid researchers in developing new hypotheses for the etiology of hip fractures...
  55. Attenuated West Nile virus envelope protein mutants
    David Beasley; Fiscal Year: 2006
    During the 2002 and 2003 transmission seasons the United States experienced large epidemics of fever and encephalitis caused by West Nile virus (WNV), with more than 13,000 cases of human disease and almost 500 deaths reported to the CDC...
    TIMOTHY DEVOOGD; Fiscal Year: 1993
    ..The studies in this proposal will generate data that will be used to design a more complete program for investigating the neural substrate of spatial learning in this system...
  57. A Longitudinal Study of Influenza Vaccine Decisions
    Gretchen Chapman; Fiscal Year: 2004
    ..most previous studies of flu shot acceptance, the current study will use a longitudinal design over three flu seasons, allow us to address research questions previously not considered...
    Peter Choo; Fiscal Year: 2000
    ..Objective 1 will evaluate the impact of temporal factors such as weekend versus weekday, holidays, seasons, and impending medical appointments on adherence by analyzing their effects on the daily rate of dosing recorded ..
  59. FAS, SIDS and Stillbirths in Cape Town, South Africa
    Sandra Jacobson; Fiscal Year: 2004
    ..abstract_text> ..
  60. Evaluation of Portable Samplers for Viable Bioaerosols
    Gediminas Mainelis; Fiscal Year: 2006
    ..airborne bacteria and fungi will also be evaluated in indoor and outdoor field environments during different seasons. Based on the obtained results, the researchers will develop practical recommendations for using the tested ..
    Againdra Bewtra; Fiscal Year: 1980
    ..IgE levels and the bronchial sensitivity in different individuals and also in the same individuals over different seasons. Henderson, et al., have shown that serum IgE levels to specific allergens vary from season to season...
  62. Non-Pharmaceutical Interventions for Pandemix Influenza
    Scott Wetterhall; Fiscal Year: 2007 officials in making recommendations for personal and organizational steps that may be taken during inter-pandemic or pandemic influenza seasons that are practical and effective. [unreadable] [unreadable] [unreadable] [unreadable]
    G Spurr; Fiscal Year: 1991
    ..Each subject will be studied on 3 occasions separated by about 3 months to cover different seasons and to allow for measurements of the growth performance of their children...
  64. DNA and Phytochemical Fingerprinting of Actaea Species
    Edward Kennelly; Fiscal Year: 2007
    ..Our long-range goals are to improve the quality of black cohosh dietary supplements and understand the variation in Actaea species. ..