biomedical research

Summary

Summary: Research that involves the application of the natural sciences, especially biology and physiology, to medicine. (from American Heritage Dictionary, 4th ed)

Top Publications

  1. ncbi Central challenges facing the national clinical research enterprise
    Nancy S Sung
    Burroughs Wellcome Fund, PO Box 13901, 21 T W Alexander Dr, Research Triangle Park, NC 27709, USA
    JAMA 289:1278-87. 2003
  2. ncbi The Connectivity Map: a new tool for biomedical research
    Justin Lamb
    Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA
    Nat Rev Cancer 7:54-60. 2007
  3. ncbi Relations in biomedical ontologies
    Barry Smith
    Institute for Formal Ontology and Medical Information Science, Saarland University, D 66041 Saarbrucken, Germany
    Genome Biol 6:R46. 2005
  4. ncbi Sex bias in neuroscience and biomedical research
    Annaliese K Beery
    Robert Wood Johnson Health and Society Scholar at University of California, San Francisco, CA, USA
    Neurosci Biobehav Rev 35:565-72. 2011
  5. ncbi Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed
    Carlijn R Hooijmans
    Radboud University Nijmegen Medical Centre, Central Animal Laboratory and 3R Research Centre, Geert Grooteplein Noord 29, route 231, Nijmegen, The Netherlands
    Lab Anim 44:170-5. 2010
  6. ncbi Sharing detailed research data is associated with increased citation rate
    Heather A Piwowar
    Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 2:e308. 2007
  7. ncbi Guidance for developers of health research reporting guidelines
    David Moher
    Ottawa Methods Centre, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
    PLoS Med 7:e1000217. 2010
  8. ncbi Contemporary low back pain research - and implications for practice
    Glenn Pransky
    Center for Disability Research, Liberty Mutual Research Institute for Safety, University of Massachusetts Medical Center, 71 Frankland Rd, Hopkinton, MA 01748, USA
    Best Pract Res Clin Rheumatol 24:291-8. 2010
  9. ncbi Prioritizing research: Patients, carers, and clinicians working together to identify and prioritize important clinical uncertainties in urinary incontinence
    Brian S Buckley
    Department of General Practice, National University of Ireland, Galway, Ireland
    Neurourol Urodyn 29:708-14. 2010
  10. ncbi Evaluating the informatics for integrating biology and the bedside system for clinical research
    Vikrant G Deshmukh
    Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84112, USA
    BMC Med Res Methodol 9:70. 2009

Research Grants

  1. IMPROVING ANIMAL RESOURCES FOR BIOMEDICAL RESEARCH
    Sylvia Kondo; Fiscal Year: 2009
  2. A novel transgenic silkworm system for recombinant glycoprotein production
    Donald L Jarvis; Fiscal Year: 2010
  3. A novel transgenic silkworm system for recombinant glycoprotein production
    Donald Jarvis; Fiscal Year: 2007
  4. A novel transgenic silkworm system for recombinant glycoprotein production
    Donald Jarvis; Fiscal Year: 2009
  5. Nanoassay for Realtime Molecular Probing ABC Transporter
    Xiaohong Xu; Fiscal Year: 2009
  6. EXTRAMURAL RESEARCH FACILITIES IMPROVEMENT PROGRAM
    John Blake; Fiscal Year: 2005
  7. RCMI-FD-Ashton Hamme, Ph.D.; Ernest B. Izevbigie, Ph.D.
    RONALD MASON; Fiscal Year: 2004
  8. EPCC'S RISE TO THE CHALLENGE PROGRAM
    Maria Alvarez; Fiscal Year: 2007
  9. SHORT-TERM TRAINING: STUDENTS IN HEALTH PROFESS. SCHOOLS
    Michael Atchison; Fiscal Year: 2007
  10. BIOMEDICAL RESEARCH INTERNSHIP PROGRAM FOR UNDERGRADUATE
    Sonia Flores; Fiscal Year: 2007

Detail Information

Publications288 found, 100 shown here

  1. ncbi Central challenges facing the national clinical research enterprise
    Nancy S Sung
    Burroughs Wellcome Fund, PO Box 13901, 21 T W Alexander Dr, Research Triangle Park, NC 27709, USA
    JAMA 289:1278-87. 2003
    ....
  2. ncbi The Connectivity Map: a new tool for biomedical research
    Justin Lamb
    Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA
    Nat Rev Cancer 7:54-60. 2007
    The ultimate objective of biomedical research is to connect human diseases with the genes that underlie them and drugs that treat them...
  3. ncbi Relations in biomedical ontologies
    Barry Smith
    Institute for Formal Ontology and Medical Information Science, Saarland University, D 66041 Saarbrucken, Germany
    Genome Biol 6:R46. 2005
    ..The resulting Relation Ontology can promote interoperability of ontologies and support new types of automated reasoning about the spatial and temporal dimensions of biological and medical phenomena...
  4. ncbi Sex bias in neuroscience and biomedical research
    Annaliese K Beery
    Robert Wood Johnson Health and Society Scholar at University of California, San Francisco, CA, USA
    Neurosci Biobehav Rev 35:565-72. 2011
    Female mammals have long been neglected in biomedical research. The NIH mandated enrollment of women in human clinical trials in 1993, but no similar initiatives exist to foster research on female animals...
  5. ncbi Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed
    Carlijn R Hooijmans
    Radboud University Nijmegen Medical Centre, Central Animal Laboratory and 3R Research Centre, Geert Grooteplein Noord 29, route 231, Nijmegen, The Netherlands
    Lab Anim 44:170-5. 2010
    ....
  6. ncbi Sharing detailed research data is associated with increased citation rate
    Heather A Piwowar
    Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 2:e308. 2007
    ..Sharing research data provides benefit to the general scientific community, but the benefit is less obvious for the investigator who makes his or her data available...
  7. ncbi Guidance for developers of health research reporting guidelines
    David Moher
    Ottawa Methods Centre, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
    PLoS Med 7:e1000217. 2010
    ..David Moher and colleagues from the EQUATOR network offer guidance and recommended steps for developing health research reporting guidelines...
  8. ncbi Contemporary low back pain research - and implications for practice
    Glenn Pransky
    Center for Disability Research, Liberty Mutual Research Institute for Safety, University of Massachusetts Medical Center, 71 Frankland Rd, Hopkinton, MA 01748, USA
    Best Pract Res Clin Rheumatol 24:291-8. 2010
    ..In this article, we review new perspectives and research studies that show promise, and suggest alternatives to current clinical and research paradigms...
  9. ncbi Prioritizing research: Patients, carers, and clinicians working together to identify and prioritize important clinical uncertainties in urinary incontinence
    Brian S Buckley
    Department of General Practice, National University of Ireland, Galway, Ireland
    Neurourol Urodyn 29:708-14. 2010
    ..This partnership of patients and clinicians aimed to identify and prioritize "clinical uncertainties" relating to treatment of urinary incontinence (UI)...
  10. ncbi Evaluating the informatics for integrating biology and the bedside system for clinical research
    Vikrant G Deshmukh
    Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84112, USA
    BMC Med Res Methodol 9:70. 2009
    ..We describe the evaluation of a free and open source cohort selection tool from the Informatics for Integrating Biology and the Bedside (i2b2) group: the i2b2 hive...
  11. ncbi Mitochondrial proteomics and its application in biomedical research
    Cristina Ruiz-Romero
    Laboratorio de Investigación Osteoarticular y del Envejecimiento, Unidad de Proteómica Nodo Asociado a ProteoRed, INIBIC Complejo Hospitalario Universitario A Coruña, 15006 A Coruna, Spain
    Mol Biosyst 5:1130-42. 2009
    ..This review will focus on the state-of-art proteomic strategies in mitochondrial research, and their application to biomedicine...
  12. ncbi A common layer of interoperability for biomedical ontologies based on OWL EL
    Robert Hoehndorf
    Department of Genetics, University of Cambridge, Cambridge, UK
    Bioinformatics 27:1001-8. 2011
    MOTIVATION: Ontologies are essential in biomedical research due to their ability to semantically integrate content from different scientific databases and resources...
  13. ncbi The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC) case register: development and descriptive data
    Robert Stewart
    King s College London, Institute of Psychiatry, London, UK
    BMC Psychiatry 9:51. 2009
    ..Recent developments in electronic medical records, and in computer software to search and analyse these in anonymised format, have the potential to revolutionise this research tool...
  14. ncbi Towards automatic recognition of scientifically rigorous clinical research evidence
    Halil Kilicoglu
    Department of Computer Science and Software Engineering, Concordia University, 1515 Ste Catherine West, Montreal, QC, H3G 1M8, Canada
    J Am Med Inform Assoc 16:25-31. 2009
    ..Our results demonstrate that a high quality gold standard and advanced classification methods can help clinicians acquire best evidence from the medical literature...
  15. ncbi The Unified Medical Language System (UMLS): integrating biomedical terminology
    Olivier Bodenreider
    Lister Hill Center for Biomedical Communications, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Nucleic Acids Res 32:D267-70. 2004
    ..All vocabularies are available at no fee for research purposes within an institution, but UMLS users are required to sign a license agreement. The UMLS knowledge sources are distributed on CD-ROM and by FTP...
  16. ncbi The relation between funding by the National Institutes of Health and the burden of disease
    C P Gross
    Robert Wood Johnson Clinical Scholars Program, Johns Hopkins University School of Medicine, Baltimore, USA
    N Engl J Med 340:1881-7. 1999
    ..The Institute of Medicine has proposed that the amount of disease-specific research funding provided by the National Institutes of Health (NIH) be systematically and consistently compared with the burden of disease for society...
  17. ncbi The poor availability of psychological research data for reanalysis
    Jelte M Wicherts
    Department of Psycology, Psychological Methods, University of Amsterdam, Roetersstraat, Amsterdam, The Netherlands
    Am Psychol 61:726-8. 2006
  18. ncbi Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology
    Hideaki Tahara
    Department of Surgery and Bioengineering, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    J Transl Med 7:45. 2009
    ..The institution of an interactive consortium for high throughput molecular monitoring of clinical trials with voluntary participation might provide cost-effective solutions...
  19. ncbi Outcome of a workshop on applications of protein models in biomedical research
    Torsten Schwede
    Swiss Institute of Bioinformatics, Biozentrum, University of Basel, Klingelbergstrasse 50 70, CH 4056 Basel, Switzerland
    Structure 17:151-9. 2009
    We describe the proceedings and conclusions from the "Workshop on Applications of Protein Models in Biomedical Research" (the Workshop) that was held at the University of California, San Francisco on 11 and 12 July, 2008...
  20. ncbi Integrating qualitative research with trials in systematic reviews
    James Thomas
    Evidence for Policy and Practice Information and Coordinating (EPPI) Centre, Social Science Research Unit, Institute of Education, London WC1H 0NR
    BMJ 328:1010-2. 2004
  21. ncbi Empirical study of data sharing by authors publishing in PLoS journals
    Caroline J Savage
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    PLoS ONE 4:e7078. 2009
    ..These policies are explicit, but remain largely untested. We sought to determine how well authors comply with such policies by requesting data from authors who had published in one of two journals with clear data sharing policies...
  22. ncbi American medical education 100 years after the Flexner report
    Molly Cooke
    Department of Medicine, University of California, San Francisco, San Francisco, USA
    N Engl J Med 355:1339-44. 2006
  23. ncbi Chinese authors do need CONSORT: reporting quality assessment for five leading Chinese medical journals
    Lin Xu
    Chinese Cochrane Centre, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China
    Contemp Clin Trials 29:727-31. 2008
    ..This study aims to evaluate the reporting quality of randomized controlled trials (RCTs) published in the five leading Chinese medical journals indexed by MEDLINE...
  24. ncbi Where is the evidence that animal research benefits humans?
    Pandora Pound
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 328:514-7. 2004
  25. ncbi Guest authorship and ghostwriting in publications related to rofecoxib: a case study of industry documents from rofecoxib litigation
    Joseph S Ross
    Department of Geriatrics and Adult Development, Mount Sinai School of Medicine, New York, New York 10029, USA
    JAMA 299:1800-12. 2008
    ..Recent litigation related to rofecoxib provided a unique opportunity to examine guest authorship and ghostwriting, practices that have been suspected in biomedical publication but for which there is little documentation...
  26. ncbi A glossary for dissemination and implementation research in health
    Borsika A Rabin
    Department of Community Health and Prevention Research Center, School of Public Health, Saint Louis University, 3545 Lafayette Ave, Salus Center 475, St Louis, MO 63104, USA
    J Public Health Manag Pract 14:117-23. 2008
    ....
  27. ncbi Informed consent in biobank research: a deliberative approach to the debate
    David M Secko
    Department of Journalism, Concordia University, 7141 Sherbrooke St West, Montreal, QC, Canada
    Soc Sci Med 68:781-9. 2009
    ..In this context, there was persistent disagreement about when consent was required for new research activities...
  28. ncbi Developing a framework for transferring knowledge into action: a thematic analysis of the literature
    Vicky Ward
    Leeds Institute of Health Sciences, University of Leeds, Leeds, UK
    J Health Serv Res Policy 14:156-64. 2009
    ..This paper describes the development of a conceptual framework of translating knowledge into action and discusses how it can be used for developing a useful model of the knowledge transfer process...
  29. ncbi Growing applications of "click chemistry" for bioconjugation in contemporary biomedical research
    Kido Nwe
    Radioimmune and Inorganic Chemistry Section, Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 1002, USA
    Cancer Biother Radiopharm 24:289-302. 2009
    ..g., biocompatibility, selectivity, yield, stereospecificity, and so forth); thus, one can expect it will consequently become a more routine strategy in the near future for a wide range of applications...
  30. ncbi The distribution of biomedical research resources and international justice
    David B Resnik
    Department of Medical Humanities New Programs, The Bioethics Center 2S 17 Brody Building, The Brody School of Medicine, East Carolina University Greenville, NC 27858 4354 USA
    Dev World Bioeth 4:42-57. 2004
    According to some estimates, less than 10% of the world's biomedical research funds are dedicated to addressing problems that are responsible for 90% of the world's burden of disease...
  31. ncbi Cross-species transfer of viruses: implications for the use of viral vectors in biomedical research, gene therapy and as live-virus vaccines
    Derrick Louz
    GMO Office, Substances Expertise Centre of the National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    J Gene Med 7:1263-74. 2005
    ..the intensified use of viruses and their genetically modified variants as viral gene transfer vectors for biomedical research, experimental gene therapy and for live-vector vaccines is a cause for concern...
  32. ncbi Advancing translational research with the Semantic Web
    Alan Ruttenberg
    Millennium Pharmaceuticals, Cambridge, MA, USA
    BMC Bioinformatics 8:S2. 2007
    ....
  33. ncbi Evaluation of email alerts in practice: Part 2. Validation of the information assessment method
    Pierre Pluye
    Department of Family Medicine, McGill University, Montreal, Canada
    J Eval Clin Pract 16:1236-43. 2010
    ..The purpose of the present paper (Part 2) is to examine the content validity of the IAM cognitive checklist when linked to email alerts...
  34. ncbi The ongoing tyranny of statistical significance testing in biomedical research
    Andreas Stang
    Institut für Klinische Epidemiologie, Medizinische Fakultat, Martin Luther Universitat Halle Wittenberg, Magdeburger Str 8, 06097, Halle Saale, Germany
    Eur J Epidemiol 25:225-30. 2010
    ..For a proper interpretation of study results, both estimated effect size and estimated precision are necessary ingredients...
  35. ncbi Toward a national framework for the secondary use of health data: an American Medical Informatics Association White Paper
    Charles Safran
    American Medical Informatics Association, 4915 St Elmo Avenue, Suite 401, Bethesda, MD 20814, USA
    J Am Med Inform Assoc 14:1-9. 2007
    ..Such a framework can guide and facilitate widespread collection, storage, aggregation, linkage, and transmission of health data. The framework will provide appropriate protections for legitimate secondary use...
  36. ncbi Funding of US biomedical research, 2003-2008
    E Ray Dorsey
    Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA
    JAMA 303:137-43. 2010
    With the exception of the American Recovery and Reinvestment Act, funding support for biomedical research in the United States has slowed after a decade of doubling. However, the extent and scope of slowing are largely unknown.
  37. ncbi Precompetitive preclinical ADME/Tox data: set it free on the web to facilitate computational model building and assist drug development
    Sean Ekins
    Collaborations in Chemistry, Jenkintown, PA 19046, USA
    Lab Chip 10:13-22. 2010
    ..cleaned and then published to the ChemSpider or other database such that it will be freely available to the biomedical research and clinical communities...
  38. ncbi A bibliometric analysis by geographic area of published research in several biomedical fields, 1995-2003
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    CMAJ 175:1389-90. 2006
    ..However, after adjustments for GDP, Canada ranked first, with the United States and Oceania following closely behind. All of the developing regions had only small research contributions in all of the biomedical fields examined...
  39. ncbi Successful aging and sustained good health in the naked mole rat: a long-lived mammalian model for biogerontology and biomedical research
    Yael H Edrey
    The Sam and Ann Barshop Institute for Longevity and Aging Studies, 15355 Lambda Drive, San Antonio, TX 78245, USA
    ILAR J 52:41-53. 2011
    ..Elucidating these mechanisms will provide useful information for enhancing human life- and healthspan, making the naked mole rat a true "supermodel" for aging research and resistance to chronic age-associated diseases...
  40. ncbi The 10/90 gap in sub-Saharan Africa: resolving inequities in health research
    Wen L Kilama
    African Malaria Network Trust, Dares Salaam, Tanzania
    Acta Trop 112:S8-S15. 2009
    ..We conclude that despite the many capacity strengthening actions, and achievements made towards resolving the 10/90 gap, the disequilibrium still persists; there is need for greater investments aimed at closing it...
  41. ncbi Current trends in antimicrobial agent research: chemo- and bioinformatics approaches
    Riadh Hammami
    STELA Dairy Research Center, Nutraceuticals and Functional Foods Institute, Universite Laval, Quebec, QC, Canada
    Drug Discov Today 15:540-6. 2010
    ..This article reviews progress in the development of computational methods, tools and databases used for organizing and extracting biological meaning from antimicrobial research...
  42. ncbi Future developments of medical informatics from the viewpoint of networked clinical research. Interoperability and integration
    C Ohmann
    Coordination Centre for Clinical Trials, Heinrich Heine University, Moorenstr 5, 40225 Duesseldorf, Germany
    Methods Inf Med 48:45-54. 2009
    ..It is the objective of our paper to give an overview of developments, indicate problem areas and to specify future requirements...
  43. ncbi Implications of correlations between skin color and genetic ancestry for biomedical research
    E J Parra
    Department of Anthropology, University of Toronto at Mississauga, Mississauga, Ontario L5L 1C6, Canada
    Nat Genet 36:S54-60. 2004
    ....
  44. ncbi Reporting recommendations for tumor marker prognostic studies (REMARK)
    Lisa M McShane
    Biometric Research Branch, National Cancer Institute, Executive Plaza North, 6130 Executive Blvd, Bethesda, MD 20892 7434, USA
    J Natl Cancer Inst 97:1180-4. 2005
    ....
  45. ncbi Pre-clinical PET/MR: technological advances and new perspectives in biomedical research
    Hans F Wehrl
    Department of Radiology, Laboratory for Preclinical Imaging and Imaging Technology of the Werner Siemens Foundation, University of Tubingen, Röntgenweg 13, 72076, Tubingen, Germany
    Eur J Nucl Med Mol Imaging 36:S56-68. 2009
    ..Especially in small-animal research, where high soft tissue contrast is required, and the scan time as well as radiation dose are critical factors, the combination of PET and MRI would be beneficial compared with PET/CT...
  46. ncbi The textual characteristics of traditional and Open Access scientific journals are similar
    Karin Verspoor
    Center for Computational Pharmacology, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    BMC Bioinformatics 10:183. 2009
    ..If this assumption is wrong, the cost to the community will be large, including not just wasted resources, but also flawed science. This paper examines that assumption...
  47. ncbi Transgenic pigs as models for translational biomedical research
    Bernhard Aigner
    Department of Veterinary Sciences and Laboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU Munich, Feodor Lynen Str 25, 81377 Munich, Germany
    J Mol Med (Berl) 88:653-64. 2010
    ..This article provides an overview of the current techniques for genetic modification of pigs and the transgenic pig models established for neurodegenerative diseases, cardiovascular diseases, cystic fibrosis, and diabetes mellitus...
  48. ncbi A new trade framework for global healthcare R&D
    Tim Hubbard
    Wellcome Trust Sanger Institute in Hinxton, United Kingdom
    PLoS Biol 2:E52. 2004
  49. ncbi The meaning of translational research and why it matters
    Steven H Woolf
    Department of Family Medicine, Virginia Commonwealth University, West Hospital, 1200 E Broad St, PO Box 980251, Richmond, VA 23298-0251, USA
    JAMA 299:211-3. 2008
  50. ncbi Do effectiveness ("real world") studies on antipsychotics tell us the real truth?
    Hans Jurgen Moller
    Department of Psychiatry, Ludwig Maximilians University Munchen, Nussbaumstrasse 7, 80336, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 258:257-70. 2008
    ..The main conclusions of these trials will be questioned on the basis of their severe methodological pitfalls...
  51. ncbi 'Fair benefits' accounts of exploitation require a normative principle of fairness: response to Gbadegesin and Wendler, and Emanuel et al
    Angela Ballantyne
    Institution for Social and Policy Studies, Interdisciplinary Center for Bioethics, Yale University, New Haven, CT 06520 8029, USA
    Bioethics 22:239-44. 2008
    ..I conclude, however, that the utility of the fair benefits model of exploitation as a policy tool will ultimately depend on whether a substantive principle of fairness can be developed to underpin it...
  52. ncbi Nutrigenomics research for personalized nutrition and medicine
    Jim Kaput
    Division of Personalized Nutrition and Medicine, FDA National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079, USA
    Curr Opin Biotechnol 19:110-20. 2008
    ....
  53. ncbi Ethical issues in research in low-income countries
    S R Benatar
    Bioethics Centre, Department of Medicine, University of Cape Town, Western Cape, South Africa
    Int J Tuberc Lung Dis 11:617-23. 2007
    ....
  54. ncbi An update on biomarkers of bone turnover and their utility in biomedical research and clinical practice
    D J Leeming
    Nordic Bioscience Diagnostics A S, 2730, Herlev, Denmark
    Eur J Clin Pharmacol 62:781-92. 2006
    ..Numerous studies have provided evidence that serum levels or urinary excretion of these biomarkers correlate with the rate of bone loss and fracture risk, proving them as useful tools for improving identification of high-risk patients...
  55. ncbi Critical appraisal of qualitative research in clinical journals challenged
    Joanna E M Sale
    Arthritis Rheum 53:314-6. 2005
  56. ncbi Sources of variation and bias in studies of diagnostic accuracy: a systematic review
    Penny Whiting
    University of York, York, United Kingdom
    Ann Intern Med 140:189-202. 2004
    ..Studies of diagnostic accuracy are subject to different sources of bias and variation than studies that evaluate the effectiveness of an intervention. Little is known about the effects of these sources of bias and variation...
  57. ncbi Alternative consent models for biobanks: the new Spanish law on biomedical research
    Antonio Casado da Rocha
    University of the Basque Country UPV EHU, Filosofia de los Valores y Antropologia Social, 70 FICE San Sebastian, Gipuzkoa 20018, Spain
    Bioethics 22:440-7. 2008
    ..samples, as well as a country report about how this issue has been regulated in Spain by means of the new Biomedical Research Act, enacted in the summer of 2007...
  58. ncbi Ethnopharmacological field studies: a critical assessment of their conceptual basis and methods
    Michael Heinrich
    Centre for Pharmacognosy and Phytotherapy, The School of Pharmacy, University of London, 29 39 Brunswick Sq, London WC1N1AX, UK
    J Ethnopharmacol 124:1-17. 2009
    ..This review cannot be a book of recipes on how to conduct such research but highlights minimal conceptual and methodological requirements for use in future projects...
  59. ncbi The tree shrews: adjuncts and alternatives to primates as models for biomedical research
    J Cao
    Department of Pathology, Guangxi Cancer Institute, Guangxi Medical University, Nanning, China
    J Med Primatol 32:123-30. 2003
    ..However, the tree shrews holds significant promise as research models and great use could be made of these animals in biomedical research.
  60. ncbi Practice-based research--"Blue Highways" on the NIH roadmap
    John M Westfall
    High Plains Research Network, Department of Family Medicine, University of Colorado Health Sciences Center, Denver, CO 80045, USA
    JAMA 297:403-6. 2007
  61. ncbi A critical appraisal of propensity-score matching in the medical literature between 1996 and 2003
    Peter C Austin
    Institute for Clinical Evaluative Sciences, Toronto, Ont, Canada
    Stat Med 27:2037-49. 2008
    ..We provide guidelines for the analysis and reporting of studies that employ propensity-score matching...
  62. ncbi Grand challenges in chronic non-communicable diseases
    Abdallah S Daar
    Program on Life Sciences, Ethics and Policy, McLaughlin-Rotman Centre for Global Health, University Health Network/University of Toronto, 101 College Street, Toronto, Ontario, M5G 1L7, Canada
    Nature 450:494-6. 2007
  63. ncbi HIV vaccine research: the way forward
    Anthony S Fauci
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, 31 Center Drive, Bethesda, MD 20892, USA
    Science 321:530-2. 2008
    ..In an era of a level budget for biomedical research at the U.S...
  64. ncbi The Spanish HIV BioBank: a model of cooperative HIV research
    Isabel García-Merino
    Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Retrovirology 6:27. 2009
    ..To carry out quality research that could eventually end in a personalized treatment for HIV, it is essential to guarantee the availability, quality and traceability of samples, under a strict system of quality management...
  65. ncbi Translational research: crossing the valley of death
    Declan Butler
    Nature 453:840-2. 2008
  66. ncbi Dissemination and publication of research findings: an updated review of related biases
    F Song
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    Health Technol Assess 14:iii, ix-xi, 1-193. 2010
    ....
  67. ncbi The effect of privacy legislation on observational research
    Andrea S Gershon
    Department of Medicine, University of Toronto and the Institute for Clinical Evaluative Sciences, Toronto, Ont
    CMAJ 178:871-3. 2008
  68. ncbi Opportunities and limitations of SELDI-TOF-MS in biomedical research: practical advices
    Terence C W Poon
    Li Ka Shing Institute of Health Sciences, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China
    Expert Rev Proteomics 4:51-65. 2007
    ..This review provides an overview of the surface-enhanced laser desorption/ionization time-of-flight mass spectrometry, discusses its limitations and provides some possible solutions to help apply this technology to biomarker research...
  69. ncbi Retractions in the scientific literature: is the incidence of research fraud increasing?
    R Grant Steen
    Medical Communications Consultants, LLC 103 Van Doren Place, Chapel Hill, NC 27517, USA
    J Med Ethics 37:249-53. 2011
    ..Growing attention to fraud in the lay press suggests that the incidence of fraud is increasing...
  70. ncbi Participants' perceptions of motivation, randomisation and withdrawal in a randomised controlled trial of interventions for prevention of depression
    J Busby Grant
    Centre for Applied Psychology Faculty of Health, University of Canberra, Canberra, ACT 2601, Australia
    J Med Ethics 35:768-73. 2009
    ..This study examined participants' motives for participating in a trial and their views of randomisation and the ability to withdraw from a randomised controlled trial (RCT) for prevention of depression...
  71. ncbi Public good, personal privacy: a citizens' deliberation about using medical information for pharmacoepidemiological research
    Lianne Parkin
    Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    J Epidemiol Community Health 65:150-6. 2011
    ..How the public weighs up these public interest and privacy arguments is unclear...
  72. ncbi The NIH-NIAID schistosomiasis resource center
    Fred A Lewis
    Biomedical Research Institute, Rockville, Maryland, United States of America
    PLoS Negl Trop Dis 2:e267. 2008
    ....
  73. ncbi At what age do biomedical scientists do their best work?
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos St, 151 23 Marousi, Athens, Greece
    FASEB J 22:4067-70. 2008
    ..In conclusion, high-quality scientific productivity in the biomedical fields as a function of investigator's age plots an inverted U-shaped curve, in which significant decreases take place from around 40 yr of age and beyond...
  74. ncbi The REUSE project: EHR as single datasource for biomedical research
    Abdennaji El Fadly
    INSERM, UMR_S 872, Paris, F 75006 France
    Stud Health Technol Inform 160:1324-8. 2010
    Integrating biomedical research and patient care is a challenging issue requiring interoperability solutions...
  75. ncbi Sex and sensitivity: the continued need for sex-based biomedical research and implementation
    Candace M Tingen
    Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Womens Health (Lond Engl) 6:511-6. 2010
    The phrase 'women's health research' embraces women as part of the biomedical research engine while categorizing women as separate...
  76. ncbi The relationship between "race" and genetics in biomedical research
    Jada Benn Torres
    Section of Genetic Medicine, Department of Medicine, The University of Chicago, 5841 South Maryland Avenue, MC6091, Chicago, IL 60637, USA
    Curr Hypertens Rep 9:196-201. 2007
    The post-human genome sequencing era has presented several daunting challenges for biomedical research. How do we begin to quantify the level of sequence variation that exists within and between human populations? This challenge has ..
  77. ncbi Identifying and prioritizing uncertainties: patient and clinician engagement in the identification of research questions
    Glyn Elwyn
    Department of Primary Care and Public Health School of Medicine, Cardiff University, Neuadd Meirionnydd, UK
    J Eval Clin Pract 16:627-31. 2010
    ....
  78. ncbi Participation in biomedical research is an imperfect moral duty: a response to John Harris
    Sandra Shapshay
    Department of Philosophy, Indiana University, 1033 E Third Street, Bloomington, IN 47405, USA
    J Med Ethics 33:414-7. 2007
    ..research is a moral duty", John Harris argues that individuals have a moral duty to participate in biomedical research by volunteering as research subjects...
  79. ncbi The first chimpanzee sanctuary in Japan: an attempt to care for the "surplus" of biomedical research
    Naruki Morimura
    Wildlife Research Center, Kyoto University, Kumamoto, Japan
    Am J Primatol 73:226-32. 2011
    ..We discuss our ethical responsibility for captive chimpanzees that have been used in biomedical research. On April 1, 2007, the Chimpanzee Sanctuary Uto (CSU) was established as the first sanctuary for retired ..
  80. ncbi Stroke: working toward a prioritized world agenda
    Vladimir Hachinski
    University of Western Ontario, University Hospital, 339 Windermere Road, London, Ontario, Canada N6A 5A5, USA
    Stroke 41:1084-99. 2010
    ..The aim of the Synergium was to devise and prioritize new ways of accelerating progress in reducing the risks, effects, and consequences of stroke...
  81. ncbi Canadian Network and Centre for Trials Internationally (CANNeCTIN): a national network for Canadian-led trials in cardiovascular diseases and diabetes mellitus
    John A Cairns
    University of British Columbia, Vancouver, British Columbia
    Can J Cardiol 26:353-8. 2010
    ....
  82. ncbi Taking tissue seriously means taking communities seriously
    Ross E G Upshur
    University of Toronto Joint Centre for Bioethics, 88 College Street, Toronto, Ontario, M5G 1L4, Canada
    BMC Med Ethics 8:11. 2007
    ..This often leads to the export of human tissue (defined broadly) from the developing to the developed world for analysis. These practices raise a number of important ethical issues that require attention...
  83. ncbi Arab nations lagging behind other Middle Eastern countries in biomedical research: a comparative study
    Hani T S Benamer
    Department of Nephrology, Clinical Sciences, Lund University, Lund, Sweden
    BMC Med Res Methodol 9:26. 2009
    Analysis of biomedical research and publications in a country or group of countries is used to monitor research progress and trends...
  84. ncbi Why do people refuse to take part in biomedical research studies? Evidence from a resource-poor area
    Joseph Mfutso-Bengo
    Centre for Bioethics in Eastern and Southern Africa, College of Medicine, Malawi
    Malawi Med J 20:57-63. 2008
    ..We conducted focus group discussions with people who had refused to take part in a number of biomedical research studies but agreed to be interviewed in this study...
  85. ncbi Proceedings of the Conference on Swine in Biomedical Research
    John K Critser
    Department of Veterinary Pathobiology, University of Missouri, N132 RADIL, 4011 Discovery Drive, Columbia, MO 65201, USA
    ILAR J 50:89-94. 2009
    The Conference on Swine in Biomedical Research was held April 2-3, 2008, in San Diego, California...
  86. ncbi Research with vulnerable human beings
    Godfrey B Tangwa
    University of Yaounde, Yaounde, Cameroon
    Acta Trop 112:S16-20. 2009
    ....
  87. ncbi Is the randomized controlled drug trial in Europe lagging behind the USA?
    Hiddo J Lambers Heerspink
    Department of Clinical Pharmacology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Br J Clin Pharmacol 66:774-80. 2008
    ..The purpose of this study was to benchmark Europe's position on drugRCTs relative to the rest of the world, and to identify factors that may drive this performance...
  88. ncbi Current status of sperm cryopreservation in biomedical research fish models: zebrafish, medaka, and Xiphophorus
    Huiping Yang
    Aquaculture Research Station, Louisiana Agricultural Experiment Station, Louisiana State University Agricultural Center, 2410 Ben Hur Road, Baton Rouge, Louisiana 70820, USA
    Comp Biochem Physiol C Toxicol Pharmacol 149:224-32. 2009
    Aquarium fishes are becoming increasingly important because of their value in biomedical research and the ornamental fish trade, and because many have become threatened or endangered in the wild...
  89. ncbi The need for veterinarians in biomedical research
    Thomas J Rosol
    College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA
    J Vet Med Educ 36:70-5. 2009
    The number of veterinarians in the United States is inadequate to meet societal needs in biomedical research and public health...
  90. ncbi Ethics committees for biomedical research in some African emerging countries: which establishment for which independence? A comparison with the USA and Canada
    Jean Paul Rwabihama
    Joffre Dupuytren Hospital, Assistance Publique Hopitaux de Paris AP HP, 91210 Draveil, France
    J Med Ethics 36:243-9. 2010
    ..This reading should benefit from an independent local ethical review of protocols. Consequently, ethics committees for medical research are evolving in Africa...
  91. ncbi Increasing contribution of China in modern biomedical research. Statistical data from ISI Web of Knowledge
    Gregory C Makris
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Med Sci Monit 15:SR15-21. 2009
    ..However, the last two decades under the pressure of globalization Chinese medicine is turning gradually to evidence-based medicine, contributing in international biomedical research.
  92. ncbi The BRIDG project: a technical report
    Douglas B Fridsma
    Department of Biomedical Informatics, Arizona State University, Phoenix, AZ 85004 2157, USA
    J Am Med Inform Assoc 15:130-7. 2008
    The Biomedical Research Integrated Domain Group (BRIDG) project is a collaborative initiative between the National Cancer Institute (NCI), the Clinical Data Interchange Standards Consortium (CDISC), the Regulated Clinical Research ..
  93. ncbi Identifying the "vulnerables" in biomedical research: the vox populis from the Tuskegee Legacy Project
    Christopher T Chiu
    Department of Epidemiology and Health Promotion, NYU College of Dentistry, 250 Park Ave South, NY, NY 10003, USA
    J Public Health Dent 71:220-8. 2011
    This report presents, for the first time, findings on the vox populis as to who constitutes the "vulnerables in biomedical research"
  94. ncbi Veterinarians in biomedical research: building national capacity
    Daryl D Buss
    School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
    J Vet Med Educ 36:62-9. 2009
    ..Summary provides the conclusions from the presentations and discussions at the conference Veterinarians in Biomedical Research-Building National Capacity, a meeting coordinated by the AAVMC and held at the National Institutes of ..
  95. ncbi What makes clinical research in developing countries ethical? The benchmarks of ethical research
    Ezekiel J Emanuel
    Department of Clinical Bioethics, Warren G Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 1156, USA
    J Infect Dis 189:930-7. 2004
  96. ncbi Enhancing cancer control programmatic and research opportunities for African-Americans through technical assistance training
    David Satcher
    Office of the President and Department of Community Health and Preventive Medicine, Morehouse School of Medicine, Atlanta, Georgia, USA
    Cancer 107:1955-61. 2006
    ..Technical assistance may improve minority recruitment/retention in CBPR cancer control research and enhance understanding and elimination of cancer health disparities among African-Americans. Cancer 2006. (c) American Cancer Society...
  97. ncbi Open access publishing in the biomedical sciences: could funding agencies accelerate the inevitable changes?
    Steven William Glover
    Librarian, Christie Hospital NHS Trust, Manchester, UK
    Health Info Libr J 23:197-202. 2006
    ..Of particular note was the stipulation that authors receiving grants must deposit their final manuscript in an open access forum within 6-12 months of publication...
  98. ncbi Academic medical centers' standards for clinical-trial agreements with industry
    Michelle M Mello
    Department of Health Policy and Management, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 352:2202-10. 2005
    ..We studied institutional standards regarding contractual provisions that restrict investigators' control over trials...
  99. ncbi The drug industry and clinical research in interwar America: three types of physician collaborator
    Nicolas Rasmussen
    School of History and Philosophy of Science, University of New South Wales, Sydney, NSW 2052, Australia
    Bull Hist Med 79:50-80. 2005
    ..These patterns may help illuminate the mutual accommodation between ethical drug firms and academic clinical researchers (and institutions) that still prevails today...
  100. ncbi Veterans Administration support for medical research: opinions of the endangered species of physician-scientists
    Stanley Zucker
    Veterans Administration Medical Centers, Northport, New York, USA
    FASEB J 18:1481-6. 2004
    ..4) The VA research program has fostered a mutually beneficial relationship with affiliated medical schools. 5) Better methods to quantify VA research contributions and outcomes are essential for future program development...
  101. ncbi Intrinsic conflicts of interest in clinical research: a need for disclosure
    Sharmon Sollitto
    Case Western University School of Law, Cleveland, OH, USA
    Kennedy Inst Ethics J 13:83-91. 2003
    ..These conflicts should be disclosed to research subjects and managed as assiduously as are financial conflicts of interest...

Research Grants74

  1. IMPROVING ANIMAL RESOURCES FOR BIOMEDICAL RESEARCH
    Sylvia Kondo; Fiscal Year: 2009
    ..institution, is committed to maintaining the highest quality Animal Care and Use Program in support of its biomedical research, education and training programs...
  2. A novel transgenic silkworm system for recombinant glycoprotein production
    Donald L Jarvis; Fiscal Year: 2010
    ..Thus, there is a high demand for systems that can be used to produce recombinant glycoproteins for basic biomedical research and direct clinical applications...
  3. A novel transgenic silkworm system for recombinant glycoprotein production
    Donald Jarvis; Fiscal Year: 2007
    ..Thus, there is a high demand for systems that can be used to produce recombinant glycoproteins for basic biomedical research and direct clinical applications...
  4. A novel transgenic silkworm system for recombinant glycoprotein production
    Donald Jarvis; Fiscal Year: 2009
    ..Thus, there is a high demand for systems that can be used to produce recombinant glycoproteins for basic biomedical research and direct clinical applications...
  5. Nanoassay for Realtime Molecular Probing ABC Transporter
    Xiaohong Xu; Fiscal Year: 2009
    ..center and enabling access to state-of-the-art instrumentation available at the center and thereby advance biomedical research. The justifications of this revision are given below: The study of membrane proteins at the molecular level ..
  6. EXTRAMURAL RESEARCH FACILITIES IMPROVEMENT PROGRAM
    John Blake; Fiscal Year: 2005
    ..Over the past three decades the State of Alaska has had surprisingly limited participation in biomedical research and we consistently lag behind the other states and territories in NIH funding...
  7. RCMI-FD-Ashton Hamme, Ph.D.; Ernest B. Izevbigie, Ph.D.
    RONALD MASON; Fiscal Year: 2004
    ..The Center has been structured to develop and sustain an adequate biomedical research infrastructure, and to serve as a platform to nurture and emphasize interdisciplinary research programs in ..
  8. EPCC'S RISE TO THE CHALLENGE PROGRAM
    Maria Alvarez; Fiscal Year: 2007
    ..lead to an increase in the number of EPCC students transferring to four-year institutions and pursuing a biomedical research career...
  9. SHORT-TERM TRAINING: STUDENTS IN HEALTH PROFESS. SCHOOLS
    Michael Atchison; Fiscal Year: 2007
    ..Recruitment of veterinarians into biomedical research careers should have a positive impact on human health...
  10. BIOMEDICAL RESEARCH INTERNSHIP PROGRAM FOR UNDERGRADUATE
    Sonia Flores; Fiscal Year: 2007
    ..students to attend graduate or professional schools and continue studies that will lead to a career in biomedical research. The UCHSC has an established commitment to increasing the diversity of its student population and to ..
  11. New Mexico IDeA Networks of Biomedical Research Excellence (INBRE) [P20]
    JEFFREY ARTERBURN; Fiscal Year: 2009
    The purpose of the New Mexico Idea Network of Biomedical Research Excellence (NM-INBRE) is to strengthen biomedical research in New Mexico's institutions of higher education and to prepare faculty and students for participation in ..