- Coral reefs under rapid climate change and ocean acidification
Centre for Marine Studies, University of Queensland, St Lucia, 4072 Queensland, Australia
Science 318:1737-42. 2007
..As the International Year of the Reef 2008 begins, scaled-up management intervention and decisive action on global emissions are required if the loss of coral-dominated ecosystems is to be avoided...
- Optimal temperature for malaria transmission is dramatically lower than previously predicted
Erin A Mordecai
Ecology, Evolution, and Marine Biology Department, University of California, Santa Barbara, CA 93106, USA
Ecol Lett 16:22-30. 2013
..Most malaria models to date assume constant or linear responses of mosquito and parasite life-history traits to temperature, predicting optimal transmission at 31 °C...
- Temperature as a universal resetting cue for mammalian circadian oscillators
Ethan D Buhr
Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208 3520, USA
Science 330:379-85. 2010
Environmental temperature cycles are a universal entraining cue for all circadian systems at the organismal level with the exception of homeothermic vertebrates...
- The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra
Ignat V Shilov
Applied Biosystems MDS Sciex, Foster City, CA 94404, USA
Mol Cell Proteomics 6:1638-55. 2007
..Sequence Temperature Values are computed using a sequence tag algorithm, allowing the degree of implication by an MS/MS spectrum of ..
- Temperature sensitivity of soil carbon decomposition and feedbacks to climate change
Eric A Davidson
The Woods Hole Research Center, PO Box 296, Woods Hole, Massachusetts 02543, USA
Nature 440:165-73. 2006
..Despite much research, a consensus has not yet emerged on the temperature sensitivity of soil carbon decomposition...
- An internal thermal sensor controlling temperature preference in Drosophila
Fumika N Hamada
National Center for Behavioral Genomics, Volen Center for Complex Systems, Biology Department, Brandeis University MS 008, 415 South Street, Waltham, Massachusetts 02454, USA
Nature 454:217-20. 2008
Animals from flies to humans are able to distinguish subtle gradations in temperature and show strong temperature preferences...
- One-third of reef-building corals face elevated extinction risk from climate change and local impacts
Kent E Carpenter
IUCN International Union for Conservation of Nature Species Programme Species Survival Commission SSC, Biological Sciences, Old Dominion University, Norfolk, VA 23529, USA
Science 321:560-3. 2008
..Our results emphasize the widespread plight of coral reefs and the urgent need to enact conservation measures...
- Effects of size and temperature on metabolic rate
J F Gillooly
Department of Biology, The University of New Mexico, Albuquerque, NM 87131, USA
Science 293:2248-51. 2001
..a general model, based on principles of biochemical kinetics and allometry, that characterizes the effects of temperature and body mass on metabolic rate...
- Climate change threats to plant diversity in Europe
Centre d Ecologie Fonctionnelle et Evolutive, Centre National de la Recherche Scientifique Unité Mixte de Recherche 5175, 1919 Route de Mende, 34293 Montpellier Cedex 5, France
Proc Natl Acad Sci U S A 102:8245-50. 2005
..and turnover were found to depend strongly on the degree of change in just two climate variables describing temperature and moisture conditions...
- Metagenomes from high-temperature chemotrophic systems reveal geochemical controls on microbial community structure and function
William P Inskeep
Thermal Biology Institute and Department of Land Resources and Environmental Sciences, Montana State University, Bozeman, Montana, United States of America
PLoS ONE 5:e9773. 2010
..contains the most numerous and diverse geothermal systems on Earth, yielding an extensive array of unique high-temperature environments that host a variety of deeply-rooted and understudied Archaea, Bacteria and Eukarya...
- The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
Frank H Niesen
Structural Genomics Consortium, Botnar Research Centre, Oxford University, Oxford, UK
Nat Protoc 2:2212-21. 2007
..The temperature at which a protein unfolds is measured by an increase in the fluorescence of a dye with affinity for ..
- Arabidopsis, the Rosetta stone of flowering time?
Gordon G Simpson
Department of Cell and Developmental Biology, John Innes Centre, Norwich, NR4 7UH, UK
Science 296:285-9. 2002
..This framework provides the basis to understand the evolution of different reproductive strategies and how floral pathways interact through seasonal progression...
- Dengue virus-mosquito interactions
Scott B Halstead
Pediatric Dengue Vaccine Initiative, Bethesda, MD 20852, USA
Annu Rev Entomol 53:273-91. 2008
..presents and discusses information on mosquito-dengue infection dynamics and describes the prominent role that temperature and rainfall play in controlling dengue viral transmission including discussions of the effect of interannual ..
- Distributed lag non-linear models
Public Health and Policy Department, London School of Hygiene and Tropical Medicine, Keppel Street, London W1C 7HT, U K
Stat Med 29:2224-34. 2010
..To illustrate the methodology we use examples of DLNMs to represent the relationship between temperature and mortality, using data from the National Morbidity, Mortality, and Air Pollution Study (NMMAPS) for New York ..
- Systematic variation in the temperature dependence of physiological and ecological traits
Anthony I Dell
Department of Biomathematics, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
Proc Natl Acad Sci U S A 108:10591-6. 2011
To understand the effects of temperature on biological systems, we compile, organize, and analyze a database of 1,072 thermal responses for microbes, plants, and animals...
- Impact of climate change on marine pelagic phenology and trophic mismatch
Sir Alister Hardy Foundation for Ocean Science, The Laboratory, Citadel Hill, Plymouth PL1 2PB, UK
Nature 430:881-4. 2004
- Giant tunnelling magnetoresistance at room temperature with MgO (100) tunnel barriers
Stuart S P Parkin
IBM Research Division, IBM Almaden Research Center, IBM Infineon MRAM Development Alliance, 650 Harry Road, San Jose, California 95120, USA
Nat Mater 3:862-7. 2004
..The performance of these devices is currently limited by the modest (< approximately 70%) room-temperature tunnelling magnetoresistance (TMR) of technologically relevant MTJs...
- UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality
Helena M Feldmann
The Wenner Gren Institute, The Arrhenius Laboratories F3, Stockholm University, Stockholm, Sweden
Cell Metab 9:203-9. 2009
..We conclude that ambient temperature is qualitatively determinative for the outcome of metabolic studies, that no other protein and no other ..
- Association between climate variability and malaria epidemics in the East African highlands
Department of Biological Sciences, State University of New York, Buffalo, NY 14260, USA
Proc Natl Acad Sci U S A 101:2375-80. 2004
..as short-term fluctuations around the mean climate state, may be epidemiologically more relevant than mean temperature change, but its effects on malaria epidemics have not been rigorously examined...
- Widespread amphibian extinctions from epidemic disease driven by global warming
J Alan Pounds
Golden Toad Laboratory for Conservation, Monteverde Cloud Forest Preserve and Tropical Science Center, Santa Elena, Puntarenas 5655 73, Costa Rica
Nature 439:161-7. 2006
..With climate change promoting infectious disease and eroding biodiversity, the urgency of reducing greenhouse-gas concentrations is now undeniable...
- Impacts of climate warming on terrestrial ectotherms across latitude
Curtis A Deutsch
Program on Climate Change and Department of Oceanography and Department of Biology, University of Washington, Seattle, WA 98195, USA
Proc Natl Acad Sci U S A 105:6668-72. 2008
..Yet the biological impact of rising temperatures also depends on the physiological sensitivity of organisms to temperature change...
- Profiling gene expression responses of coral larvae (Acropora millepora) to elevated temperature and settlement inducers using a novel RNA-Seq procedure
Integrative Biology Section, The University of Texas at Austin, Austin, TX 78712, USA
Mol Ecol 20:3599-616. 2011
..Future studies of gene expression in corals will have to address this genetic variation, which could have important adaptive consequences for corals during global climate change...
- Temperature and mortality in 11 cities of the eastern United States
Frank C Curriero
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Epidemiol 155:80-7. 2002
..Time-series analyses show an association between temperature and mortality across a range of less extreme temperatures...
- Design of a novel globular protein fold with atomic-level accuracy
Department of Biochemistry, University of Washington, Seattle, WA 98195, USA
Science 302:1364-8. 2003
..2 angstroms) to the design model. The ability to design a new protein fold makes possible the exploration of the large regions of the protein universe not yet observed in nature...
- The influence of mosquito resting behaviour and associated microclimate for malaria risk
Krijn P Paaijmans
Center for Infectious Disease Dynamics and Department of Entomology, Merkle Lab, Penn State University, University Park, PA 16802, USA
Malar J 10:183. 2011
..of the mosquito and parasite life-history traits that combine to determine malaria transmission intensity are temperature sensitive...
- Heterotrophic plasticity and resilience in bleached corals
Andréa G Grottoli
Department of Geological Sciences, Ohio State University, Columbus, Ohio 43210, USA
Nature 440:1186-9. 2006
- Understanding the link between malaria risk and climate
Krijn P Paaijmans
Center for Infectious Disease Dynamics, Department of Entomology, Chemical Ecology Laboratory, Pennsylvania State University, University Park, PA 16802, USA
Proc Natl Acad Sci U S A 106:13844-9. 2009
The incubation period for malaria parasites within the mosquito is exquisitely temperature-sensitive, so that temperature is a major determinant of malaria risk...
- Global patterns and predictors of marine biodiversity across taxa
Derek P Tittensor
Department of Biology, Dalhousie University, 1355 Oxford Street, Halifax B3H 4J1, Canada
Nature 466:1098-101. 2010
..Spatial regression analyses revealed sea surface temperature as the only environmental predictor highly related to diversity across all 13 taxa...
- North American West Nile virus genotype isolates demonstrate differential replicative capacities in response to temperature
Christy C Andrade
Center for Vector Borne Diseases and Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, CA, USA
J Gen Virol 92:2523-33. 2011
..embryonic fibroblast (DEF) cell lines at differing, biologically relevant temperatures to assess the relative temperature sensitivities of these natural isolates...
- Effects of temperature on emergence and seasonality of West Nile virus in California
David M Hartley
Georgetown University Medical Center, Washington, District of Columbia 20057, USA
Am J Trop Med Hyg 86:884-94. 2012
b>Temperature has played a critical role in the spatiotemporal dynamics of West Nile virus transmission throughout California from its introduction in 2003 through establishment by 2009...
- Forecast of dengue incidence using temperature and rainfall
Yien Ling Hii
Umeå Centre for Global Health Research, Epidemiology and Global Health, Department of Public Health and Clinical Medicine, Umea University, Umea, Sweden
PLoS Negl Trop Dis 6:e1908. 2012
..The aim of this study was to develop and validate a forecasting model that could predict dengue cases and provide timely early warning in Singapore...
- The physiology of climate change: how potentials for acclimatization and genetic adaptation will determine 'winners' and 'losers'
G N Somero
Hopkins Marine Station, Department of Biology, Stanford University, Pacific Grove, CA 93950, USA
J Exp Biol 213:912-20. 2010
..genes and gene regulatory mechanisms--influence capacities for adapting to acute and long-term increases in temperature. Studies of congeneric invertebrates from thermally stressful rocky intertidal habitats have shown that warm-..
- Peripheral protein quality control removes unfolded CFTR from the plasma membrane
Department of Physiology, and Groupe de Recherche Axé sur la Structure des Protéine GRASP McGill University, Montreal, Quebec H3G 1Y6, Canada
Science 329:805-10. 2010
- Development of a new version of the Liverpool Malaria Model. I. Refining the parameter settings and mathematical formulation of basic processes based on a literature review
Institute of Geophysics and Meteorology, University of Cologne, Cologne, Germany
Malar J 10:35. 2011
..The Liverpool Malaria Model (LMM) is a mathematical-biological model of malaria parasite dynamics using daily temperature and precipitation data...
- The effect of temperature on mortality in rural Bangladesh--a population-based time-series study
Institute of Tropical Medicine, Nagasaki University, 1 12 4, Sakamoto, Nagasaki 852 8523, Japan
Int J Epidemiol 38:1689-97. 2009
..However, few studies have examined temperature-mortality relationship in the rural areas of developing countries...
- The impact of temperature on mortality in Tianjin, China: a case-crossover design with a distributed lag nonlinear model
School of Public Health, Queensland University of Technology, Brisbane, Australia
Environ Health Perspect 119:1719-25. 2011
Although interest in assessing the impacts of temperature on mortality has increased, few studies have used a case-crossover design to examine nonlinear and distributed lag effects of temperature on mortality...
- Drought, salt, and temperature stress-induced metabolic rearrangements and regulatory networks
GMI Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, Dr Bohr Gasse 3, 1030 Vienna, Austria
J Exp Bot 63:1593-608. 2012
..In this review, information about metabolic regulation in response to drought, extreme temperature, and salinity stress is summarized and the signalling events involved in mediating stress-induced metabolic ..
- Climate change and distribution shifts in marine fishes
Allison L Perry
Centre for Ecology, Evolution and Conservation, School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK
Science 308:1912-5. 2005
..of both exploited and nonexploited North Sea fishes have responded markedly to recent increases in sea temperature, with nearly two-thirds of species shifting in mean latitude or depth or both over 25 years...
- Influence of temperature on immature development, survival, longevity, fecundity, and gonotrophic cycles of Aedes albopictus, vector of chikungunya and dengue in the Indian Ocean
Research Unit 016, Institut de recherche pour le developpement IRD, 7 chemin de l IRAT, 97410 Saint Pierre, La Reunion, France
J Med Entomol 46:33-41. 2009
..5 d). Those results are according to the field repartition of this species in La Réunion, allowing Ae. albopictus survival at a large range of temperatures...
- Coral reefs: corals' adaptive response to climate change
Andrew C Baker
Marine Program, Wildlife Conservation Society, Bronx, New York 10460, USA
Nature 430:741. 2004
..that corals containing unusual algal symbionts that are thermally tolerant and commonly associated with high-temperature environments are much more abundant on reefs that have been severely affected by recent climate change...
- Climate. Blooms like it hot
Hans W Paerl
Institute of Marine Sciences, University of North Carolina at Chapel Hill, Morehead City, NC 28557, USA
Science 320:57-8. 2008
- Identification and importance of brown adipose tissue in adult humans
Aaron M Cypess
Research Division, Joslin Diabetes Center, Boston, MA 02215, USA
N Engl J Med 360:1509-17. 2009
- Implications of temperature variation for malaria parasite development across Africa
J I Blanford
GeoVISTA Center, Department of Geography, The Pennsylvania State University, University Park, PA, USA
Sci Rep 3:1300. 2013
b>Temperature is an important determinant of malaria transmission. Recent work has shown that mosquito and parasite biology are influenced not only by average temperature, but also by the extent of the daily temperature variation...
- Thermofluor-based high-throughput stability optimization of proteins for structural studies
Ulrika B Ericsson
Department of Biochemistry and Biophysics, Stockholm University, Stockholm SE 109 51, Sweden
Anal Biochem 357:289-98. 2006
..This suggests that thermofluor constitutes an efficient generic high-throughput method for identification of protein properties predictive of crystallizability...
- Temperature, viral genetics, and the transmission of West Nile virus by Culex pipiens mosquitoes
A Marm Kilpatrick
Consortium for Conservation Medicine, New York, New York, United States of America
PLoS Pathog 4:e1000092. 2008
..Vector competence, in turn, can be influenced by temperature and viral genetics...
- A review of the likely effects of climate change on anadromous Atlantic salmon Salmo salar and brown trout Salmo trutta, with particular reference to water temperature and flow
Norwegian Institute for Nature Research, Gaustadalleen 21, N 0349 Oslo, Norway
J Fish Biol 75:2381-447. 2009
The present paper reviews the effects of water temperature and flow on migrations, embryonic development, hatching, emergence, growth and life-history traits in light of the ongoing climate change with emphasis on anadromous Atlantic ..
- DNA methylation of the gonadal aromatase (cyp19a) promoter is involved in temperature-dependent sex ratio shifts in the European sea bass
Institut de Ciencies del Mar, Consejo Superior de Investigaciones Cientificas CSIC, Barcelona, Spain
PLoS Genet 7:e1002447. 2011
Sex ratio shifts in response to temperature are common in fish and reptiles. However, the mechanism linking temperature during early development and sex ratios has remained elusive...
- Reduction of Aedes aegypti vector competence for dengue virus under large temperature fluctuations
Lauren B Carrington
Department of Entomology, University of California, Davis, CA95616, USA
Am J Trop Med Hyg 88:689-97. 2013
Diurnal temperature fluctuations can fundamentally alter mosquito biology and mosquito-virus interactions in ways that impact pathogen transmission...
- Global control of dimorphism and virulence in fungi
Julie C Nemecek
Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, University of Wisconsin Hospital and Clinics, Madison, WI 53792, USA
Science 312:583-8. 2006
..switch from nonpathogenic molds in soil to pathogenic yeast after spores are inhaled and exposed to elevated temperature. Mechanisms that regulate this switch remain obscure...
- Global warming, elevational range shifts, and lowland biotic attrition in the wet tropics
Robert K Colwell
Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT 06269, USA
Science 322:258-61. 2008
..at temperate latitudes, but evidence for range shifts is scarce for the tropics, where the shallow latitudinal temperature gradient makes upslope shifts more likely than poleward shifts...
- Time series analysis of Japanese encephalitis and weather in Linyi City, China
School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong SAR, China
Int J Public Health 57:289-96. 2012
..To examine the relationship between meteorological factors and epidemiological pattern of Japanese encephalitis in Linyi City during 1956-2004...
- High temperature (30 degrees C) blocks aerosol but not contact transmission of influenza virus
Anice C Lowen
Department of Microbiology, Mount Sinai School of Medicine, New York, New York 10029, USA
J Virol 82:5650-2. 2008
..Our data imply that contact or short-range spread predominates in the tropics and offer an explanation for the lack of a well-defined, recurrent influenza season affecting tropical and subtropical regions of the world...
- Larval environmental temperature and the susceptibility of Aedes albopictus Skuse (Diptera: Culicidae) to Chikungunya virus
Catherine J Westbrook
Florida Medical Entomology Laboratory, Department of Entomology and Nematology, Institute of Food and Agricultural Sciences, University of Florida, Vero Beach, Florida 32962, USA
Vector Borne Zoonotic Dis 10:241-7. 2010
..Adult females with the largest body size were produced from the coolest temperature, took the longest to mature, and six times more likely to be infected with CHIKV than females reared at 32 ..
- Ecologically relevant measures of tolerance to potentially lethal temperatures
John S Terblanche
Department of Conservation Ecology and Entomology, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa
J Exp Biol 214:3713-25. 2011
..An important area for further development is to identify the impact of rates of temperature change under field and laboratory conditions.
- Climate warming and disease risks for terrestrial and marine biota
C Drew Harvell
Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY 14853, USA
Science 296:2158-62. 2002
..Many pathogens of terrestrial and marine taxa are sensitive to temperature, rainfall, and humidity, creating synergisms that could affect biodiversity...
- Models for the relationship between ambient temperature and daily mortality
London School of Hygiene and Tropical Medicine, London, UK
Epidemiology 17:624-31. 2006
Ambient temperature is an important determinant of daily mortality that is of interest both in its own right and as a confounder of other determinants investigated using time-series regressions, in particular, air pollution...
- Forests and climate change: forcings, feedbacks, and the climate benefits of forests
Gordon B Bonan
National Center for Atmospheric Research, P O Box 3000, Boulder, Colorado 80307, USA
Science 320:1444-9. 2008
- The single-nucleotide resolution transcriptome of Pseudomonas aeruginosa grown in body temperature
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel
PLoS Pathog 8:e1002945. 2012
..aeruginosa grown at 28°C and 37°C we detected genes preferentially expressed at the body temperature of mammalian hosts, suggesting that they play a role during infection...
- Coral bleaching: thermal adaptation in reef coral symbionts
University of Guam Marine Laboratory, Mangilao, Guam 96923, USA
Nature 430:742. 2004
Many corals bleach as a result of increased seawater temperature, which causes them to lose their vital symbiotic algae (Symbiodinium spp...
- Membrane lipids of symbiotic algae are diagnostic of sensitivity to thermal bleaching in corals
Environmental Biophysics and Molecular Ecology Program, Institute of Marine and Coastal Sciences, Rutgers, The State University of New Jersey, 71 Dudley Road, New Brunswick, NJ 08901, USA
Proc Natl Acad Sci U S A 101:13531-5. 2004
..Although the phenomenon is correlated with relatively small increases in sea-surface temperature and enhanced light intensity, the underlying physiological mechanism remains unknown...
- Proteomics applied on plant abiotic stresses: role of heat shock proteins (HSP)
Anna Maria Timperio
Department of Environmental Sciences, University of Tuscia, Largo dell Università snc, 01100 Viterbo, Italy
J Proteomics 71:391-411. 2008
- H2A.Z-containing nucleosomes mediate the thermosensory response in Arabidopsis
S Vinod Kumar
John Innes Centre, Colney Lane, Norwich NR4 7UH, UK
Cell 140:136-47. 2010
Plants are highly sensitive to temperature and can perceive a difference of as little as 1 degrees C. How temperature is sensed and integrated in development is unknown...
- Conditional modification of behavior in Drosophila by targeted expression of a temperature-sensitive shibire allele in defined neurons
Division of Neurosciences, Beckman Research Institute of the City of Hope, 1450 East Duarte Road, Duarte, California 91010, USA
J Neurobiol 47:81-92. 2001
..In this method, a temperature-sensitive allele of shibire (shi(ts1)) is overexpressed in neuronal subsets using the GAL4/UAS system...
- N-acylhomoserine lactones undergo lactonolysis in a pH-, temperature-, and acyl chain length-dependent manner during growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa
Edwin A Yates
School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom
Infect Immun 70:5635-46. 2002
..Raising the temperature from 22 to 37 degrees C increased the rate of ring opening...
- International study of temperature, heat and urban mortality: the 'ISOTHURM' project
Anthony J McMichael
National Centre for Epidemiology and Population Health, The Australian National University College of Medicine and Health Sciences, Canberra, Australia
Int J Epidemiol 37:1121-31. 2008
This study describes heat- and cold-related mortality in 12 urban populations in low- and middle-income countries, thereby extending knowledge of how diverse populations, in non-OECD countries, respond to temperature extremes.
- Influence of climate on malaria transmission depends on daily temperature variation
Krijn P Paaijmans
Department of Entomology, Center for Infectious Disease Dynamics, Penn State University, University Park, PA 16802, USA
Proc Natl Acad Sci U S A 107:15135-9. 2010
Malaria transmission is strongly influenced by environmental temperature, but the biological drivers remain poorly quantified...
- Evolution and biogeography of deep-sea vent and seep invertebrates
C L Van Dover
Biology Department, College of William and Mary, Williamsburg, VA 23187, USA
Science 295:1253-7. 2002
..The recent evolution of many vent and seep invertebrate species (<100 million years ago) suggests that Cenozoic tectonic history and oceanic circulation patterns have been important in defining contemporary biogeographic patterns...
- Rapid changes in flowering time in British plants
A H Fitter
Department of Biology, University of York, York YO10 5DD, UK
Science 296:1689-91. 2002
..Flowering is especially sensitive to the temperature in the previous month, and spring-flowering species are most responsive...
- Effect of primer mismatch, annealing temperature and PCR cycle number on 16S rRNA gene-targetting bacterial community analysis
Department of Microbiology, Eötvös Loránd University of Science, Budapest, Hungary
FEMS Microbiol Ecol 60:341-50. 2007
..investigated using 'universal' bacteria-specific primers, focusing on the effect of primer mismatch, annealing temperature and PCR cycle number...
- Ocean acidification causes bleaching and productivity loss in coral reef builders
K R N Anthony
Centre for Marine Studies, The University of Queensland, St Lucia 4072 Queensland, Australia
Proc Natl Acad Sci U S A 105:17442-6. 2008
..Our findings suggest that sensitive reef-building species such as CCA may be pushed beyond their thresholds for growth and survival within the next few decades whereas corals will show delayed and mixed responses...
- Trends, rhythms, and aberrations in global climate 65 Ma to present
Earth Sciences Department, University of California, Santa Cruz, CA 95064, USA
Science 292:686-93. 2001
..We also consider how this improved perspective has led to the recognition of previously unforeseen mechanisms for altering climate...
- Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination
Structural Genomics Consortium, University of Toronto, 100 College Street, Toronto, ON, Canada M5G 1L5
Proc Natl Acad Sci U S A 103:15835-40. 2006
..The methods are cost-effective, can be implemented in any laboratory, promise to increase the success rates of purifying and crystallizing human proteins significantly, and identify new ligands for these proteins...
- Climate change affects marine fishes through the oxygen limitation of thermal tolerance
Hans O Portner
Alfred Wegener Institute for Polar and Marine Research, Animal Ecophysiology, Postfach 12 01 61, 27515 Bremerhaven, Germany
Science 315:95-7. 2007
..Decrements in aerobic performance in warming seas will thus be the first process to cause extinction or relocation to cooler waters...
- Attributing physical and biological impacts to anthropogenic climate change
NASA Goddard Institute for Space Studies and Columbia Center for Climate Systems Research, 2800 Broadway, New York, New York 10025, USA
Nature 453:353-7. 2008
..Most of these changes are in the direction expected with warming temperature. Here we show that these changes in natural systems since at least 1970 are occurring in regions of observed ..
- Modular thermal sensors in temperature-gated transient receptor potential (TRP) channels
Department of Physiology and Biophysical Sciences, State University of New York at Buffalo, Buffalo, NY 14214, USA
Proc Natl Acad Sci U S A 108:11109-14. 2011
The molecular basis of the thermal sensitivity of temperature-sensitive channels appears to arise from a specific protein domain rather than integration of global thermal effects...
- Long-term monitoring of fresco paintings in the cathedral of Valencia (Spain) through humidity and temperature sensors in various locations for preventive conservation
Department of Applied Statistics, Operations Research and Quality, Universidad Politecnica de Valencia, Camino de Vera s n, 46022 Valencia, Spain
Sensors (Basel) 11:8685-710. 2011
..This system comprises 29 relative humidity (RH) and temperature sensors: 10 of them inserted into the plaster layer supporting the fresco paintings, 10 sensors in the walls ..
- Mutations in a cyclic nucleotide-gated channel lead to abnormal thermosensation and chemosensation in C. elegans
Department of Biology, Faculty of Science, Kyushu University, Fukuoka, Japan
Neuron 17:707-18. 1996
The C. elegans tax-4 mutants are abnormal in multiple sensory behaviors: they fail to respond to temperature or to water-soluble or volatile chemical attractants...
- Product differentiation by analysis of DNA melting curves during the polymerase chain reaction
K M Ririe
Idaho Technology Inc, Idaho Falls 83402, USA
Anal Biochem 245:154-60. 1997
..Plotting fluorescence as a function of temperature as the thermal cycler heats through the dissociation temperature of the product gives a DNA melting curve...
- Hsp90 as a capacitor for morphological evolution
S L Rutherford
Howard Hughes Medical Institute, University of Chicago, Illinois 60637, USA
Nature 396:336-42. 1998
..When Hsp90 buffering is compromised, for example by temperature, cryptic variants are expressed and selection can lead to the continued expression of these traits, even when ..
- Dissecting the architecture of a quantitative trait locus in yeast
Lars M Steinmetz
Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA
Nature 416:326-30. 2002
..It also demonstrates a deficiency in current approaches to QTL dissection with implications extending to traits in other organisms, including human genetic diseases...
- Is hand, foot and mouth disease associated with meteorological parameters?
Surveillance and Epidemiology Branch, Centre for Health Protection, Department of Health, Hong Kong Special Administrative Region
Epidemiol Infect 138:1779-88. 2010
..After adjusting for the effect of collinearity, mean temperature, diurnal difference in temperature, relative humidity, and wind speed were positively associated with HFMD ..
- Climate-based models for understanding and forecasting dengue epidemics
UMR190, Emergence of Viral Pathologies, Institute of Research for the Development, Aix Marseille University, Marseille, France
PLoS Negl Trop Dis 6:e1470. 2012
..The objectives of this study were to analyze and model the relationships between climate, Aedes aegypti vectors and dengue outbreaks in Noumea (New Caledonia), and to provide an early warning system...
- Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases
J S Robinson
Division of Biology, California Institute of Technology, Pasadena 91125
Mol Cell Biol 8:4936-48. 1988
..vpt16, vpt18, vpt29, and vpt33) contained alleles that led to a conditional lethal phenotype; the mutants were temperature sensitive for vegetative cell growth...
- Different trajectories of parallel evolution during viral adaptation
H A Wichman
Department of Biological Sciences, University of Idaho, Moscow, ID 83844, USA
Science 285:422-4. 1999
..However, the order of these changes differed between replicates, and parallel substitutions did not reflect the changes with the largest beneficial effects or indicate a common trajectory of adaptation...
- Impact of nitrogen deposition on the species richness of grasslands
Carly J Stevens
Department of Earth Sciences, The Open University, Milton Keynes MK7 6AA, UK
Science 303:1876-9. 2004
..At the mean chronic nitrogen deposition rate of central Europe (17 kg Nha-1 year-1), there is a 23% species reduction compared with grasslands receiving the lowest levels of nitrogen deposition...
- Growth, activity and temperature responses of ammonia-oxidizing archaea and bacteria in soil microcosms
School of Biological Sciences, University of Aberdeen, Cruickshank Building, St Machar Drive, Aberdeen AB24 3UU, UK
Environ Microbiol 10:1357-64. 2008
..In this study, we have determined the influence of temperature on the response of ammonia-oxidizing bacteria and archaea in nitrifying soil microcosms using two approaches, ..
- Declining coral calcification on the Great Barrier Reef
Australian Institute of Marine Science, Townsville, Queensland 4810, Australia
Science 323:116-9. 2009
..Calcification increases linearly with increasing large-scale sea surface temperature but responds nonlinearly to annual temperature anomalies...
- Optimized molecular dynamics force fields applied to the helix-coil transition of polypeptides
Robert B Best
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U K
J Phys Chem B 113:9004-15. 2009
..However, despite the agreement at ambient conditions, the dependence of the helix content on temperature is too weak, a problem shared with other force fields...
- The influence of temperature and humidity on the incidence of hand, foot, and mouth disease in Japan
Department of Public Health and Medical Affairs, Fukuoka Prefectural Government, 7 7 Higashi koen, Hakata Ku, Fukuoka shi, Fukuoka 812 8577, Japan
Sci Total Environ 410:119-25. 2011
..However, the impact of weather fluctuations on hand, foot, and mouth disease (HFMD), which primarily affects children, is not well understood...
- Warming experiments underpredict plant phenological responses to climate change
E M Wolkovich
Division of Biological Sciences, University of California San Diego, 9500 Gilman Drive 0116, La Jolla, California 92093, USA
Nature 485:494-7. 2012
..to provide meaningful predictions of future responses, they should reflect the empirical record of responses to temperature variability and recent warming, including advances in the timing of flowering and leafing...
- Perception of climate change
National Aeronautics and Space Administration Goddard Institute for Space Studies, New York, NY 10025, USA
Proc Natl Acad Sci U S A 109:E2415-23. 2012
..The distribution of seasonal mean temperature anomalies has shifted toward higher temperatures and the range of anomalies has increased...
- Rapid folding of DNA into nanoscale shapes at constant temperature
Jean Philippe J Sobczak
Physics Department, Walter Schottky Institute, Technische Universitat Munchen, Am Coulombwall 4a, 85748 Garching near Munich, Germany
Science 338:1458-61. 2012
We demonstrate that, at constant temperature, hundreds of DNA strands can cooperatively fold a long template DNA strand within minutes into complex nanoscale objects...
- Simultaneous femtosecond X-ray spectroscopy and diffraction of photosystem II at room temperature
Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
Science 340:491-5. 2013
..diffraction (XRD) and x-ray emission spectroscopy (XES) of microcrystals of photosystem II (PS II) at room temperature. This method probes the overall protein structure and the electronic structure of the Mn4CaO5 cluster in the ..
- Structural changes in dengue virus when exposed to a temperature of 37°C
Program in Emerging Infectious Diseases, Duke NUS Graduate Medical School, Singapore
J Virol 87:7585-92. 2013
..fully hidden epitope suggest that insect cell-derived dengue virus undergoes structural changes at an elevated temperature. This was confirmed by our cryo-electron microscopy images of dengue virus incubated at 37°C, where viruses ..
- Fat cells directly sense temperature to activate thermogenesis
Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 110:12480-5. 2013
..indirectly through the sympathetic nervous systems and β-adrenergic signaling, but here we report that cool temperature (27-33 °C) can directly activate a thermogenic gene program in adipocytes in a cell-autonomous manner...
- Temperature triggers immune evasion by Neisseria meningitidis
Sir William Dunn School of Pathology, University of Oxford, Sir Parks Road, Oxford OX1 3RE, UK
Nature 502:237-40. 2013
..meningococcal immune evasion and resistance against complement increase in response to an increase in ambient temperature. We have identified three independent RNA thermosensors located in the 5' untranslated regions of genes ..
- Effect of temperature on the development of the aquatic stages of Anopheles gambiae sensu stricto (Diptera: Culicidae)
M N Bayoh
School of Biological and Biomedical Sciences Science Laboratories, University of Durham Durham DH1 3LE UK
Bull Entomol Res 93:375-81. 2003
Global warming may affect the future pattern of many arthropod-borne diseases, yet the relationship between temperature and development has been poorly described for many key vectors...
- Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery
Mei Chu Lo
Biophysics Enzymology Chemical and Screening Sciences, Wyeth Research, Pearl River, NY 10965, USA
Anal Biochem 332:153-9. 2004
..monitor protein thermal unfolding, the ligand-binding affinity can be assessed from the shift of the unfolding temperature (Delta Tm) obtained in the presence of ligands relative to that obtained in the absence of ligands...
- Long-term region-wide declines in Caribbean corals
Toby A Gardner
School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK
Science 301:958-60. 2003
..The ability of Caribbean coral reefs to cope with future local and global environmental change may be irretrievably compromised...
- Fingerprints of global warming on wild animals and plants
Terry L Root
Center for Environmental Science and Policy, Institute for International Studies, Stanford University, Stanford, California 94305, USA
Nature 421:57-60. 2003
Over the past 100 years, the global average temperature has increased by approximately 0.6 degrees C and is projected to continue to rise at a rapid rate...
- Who is sensitive to extremes of temperature?: A case-only analysis
Exposure, Epidemiology, and Risk Program Harvard School of Public Health, Boston, Massachusetts 02215, USA
Epidemiology 16:67-72. 2005
Extremes of temperature are well known to be associated with excess mortality. Less is known about the characteristics of persons that put them at higher risk, particularly the role of medical conditions.