phase transition

Summary

Summary: A change of a substance from one form or state to another.

Top Publications

  1. ncbi Low-temperature synthesis of gamma-alumina nanocrystals from aluminum acetylacetonate in nonaqueous media
    Shuxue Zhou
    Max Planck Institute of Colloids and Interfaces, Colloid Department, Research Campus Golm, Potsdam, Germany
    Small 3:763-7. 2007
  2. ncbi Domain nucleation rates and interfacial line tensions in supported bilayers of ternary mixtures containing galactosylceramide
    Craig D Blanchette
    Biophysics Graduate Group, College of Biological Sciences, Lawrence Livermore National Laboratory, Livermore, California, USA
    Biophys J 94:2691-7. 2008
  3. ncbi Phase transition kinetics of lipid bilayer membranes studied by time-resolved pressure perturbation calorimetry
    Martin Schiewek
    Faculty of Chemistry and Physics, Institute of Chemistry, Martin Luther University Halle Wittenberg, Muehlpforte 1, 06108, Halle Saale, Germany
    Eur Biophys J 39:815-24. 2010
  4. ncbi Ferroelectric phase transition in individual single-crystalline BaTiO3 nanowires
    Jonathan E Spanier
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    Nano Lett 6:735-9. 2006
  5. ncbi Comparison between protein-polyethylene glycol (PEG) interactions and the effect of PEG on protein-protein interactions using the liquid-liquid phase transition
    Ying Wang
    Department of Chemistry, Texas Christian University, Fort Worth, Texas 76129, USA
    J Phys Chem B 111:1222-30. 2007
  6. ncbi Soft perforation of planar bilayer lipid membranes of dipalmitoylphosphatidylcholine at the temperature of the phase transition from the liquid crystalline to the gel state
    Valerij F Antonov
    Department of Medical and Biological Physics, Sechenov Moscow Medical Academy, Russia
    Eur Biophys J 34:155-62. 2005
  7. ncbi Porous bioactive nanostructured scaffolds for bone regeneration: a sol-gel solution
    Oliver Mahony
    Imperial College London, Department of Materials, South Kensington Campus, London, SW7 2AZ, UK
    Nanomedicine (Lond) 3:233-45. 2008
  8. ncbi Molecular studies of the gel to liquid-crystalline phase transition for fully hydrated DPPC and DPPE bilayers
    Sukit Leekumjorn
    Virginia Polytechnic Institute and State University, Department of Chemical Engineering, Blacksburg VA 24061, USA
    Biochim Biophys Acta 1768:354-65. 2007
  9. ncbi Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles
    Tobias Baumgart
    School of Applied and Engineering Physics and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA
    Proc Natl Acad Sci U S A 104:3165-70. 2007
  10. ncbi Structure of fully hydrated fluid phase lipid bilayers with monounsaturated chains
    Norbert Kucerka
    Physics Department, Carnegie Mellon University, Pittsburgh, Pennsylvania, 15213, USA
    J Membr Biol 208:193-202. 2005

Detail Information

Publications257 found, 100 shown here

  1. ncbi Low-temperature synthesis of gamma-alumina nanocrystals from aluminum acetylacetonate in nonaqueous media
    Shuxue Zhou
    Max Planck Institute of Colloids and Interfaces, Colloid Department, Research Campus Golm, Potsdam, Germany
    Small 3:763-7. 2007
  2. ncbi Domain nucleation rates and interfacial line tensions in supported bilayers of ternary mixtures containing galactosylceramide
    Craig D Blanchette
    Biophysics Graduate Group, College of Biological Sciences, Lawrence Livermore National Laboratory, Livermore, California, USA
    Biophys J 94:2691-7. 2008
    ..Our line tension measurements are discussed in combination with recent line tension measurements to address line tension regulation by cholesterol and the dynamic nature of membrane rafts...
  3. ncbi Phase transition kinetics of lipid bilayer membranes studied by time-resolved pressure perturbation calorimetry
    Martin Schiewek
    Faculty of Chemistry and Physics, Institute of Chemistry, Martin Luther University Halle Wittenberg, Muehlpforte 1, 06108, Halle Saale, Germany
    Eur Biophys J 39:815-24. 2010
    ..with the instrumental response function gives information about slow processes connected with the lipid phase transition. The lipid transition from the gel to the liquid-crystalline state was found to be a multi-step process with ..
  4. ncbi Ferroelectric phase transition in individual single-crystalline BaTiO3 nanowires
    Jonathan E Spanier
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    Nano Lett 6:735-9. 2006
    We report scanned probe characterizations of the ferroelectric phase transition in individual barium titanate (BaTiO3) nanowires...
  5. ncbi Comparison between protein-polyethylene glycol (PEG) interactions and the effect of PEG on protein-protein interactions using the liquid-liquid phase transition
    Ying Wang
    Department of Chemistry, Texas Christian University, Fort Worth, Texas 76129, USA
    J Phys Chem B 111:1222-30. 2007
    ..Finally, due to the general importance of LLPS, we will experimentally show that protein-PEG-buffer mixtures can exhibit two distinct types of liquid-liquid phase transitions...
  6. ncbi Soft perforation of planar bilayer lipid membranes of dipalmitoylphosphatidylcholine at the temperature of the phase transition from the liquid crystalline to the gel state
    Valerij F Antonov
    Department of Medical and Biological Physics, Sechenov Moscow Medical Academy, Russia
    Eur Biophys J 34:155-62. 2005
    ..structural rearrangement of the lipid bilayer formed from disaturated phospholipids at the temperature of the phase transition from the liquid crystalline state to the gel state...
  7. ncbi Porous bioactive nanostructured scaffolds for bone regeneration: a sol-gel solution
    Oliver Mahony
    Imperial College London, Department of Materials, South Kensington Campus, London, SW7 2AZ, UK
    Nanomedicine (Lond) 3:233-45. 2008
    ..Composites provide a partial solution to this problem, although their bioactive and degradation properties are not ideal, therefore novel nanocomposites are needed. The route to these potentially ideal materials is described...
  8. ncbi Molecular studies of the gel to liquid-crystalline phase transition for fully hydrated DPPC and DPPE bilayers
    Sukit Leekumjorn
    Virginia Polytechnic Institute and State University, Department of Chemical Engineering, Blacksburg VA 24061, USA
    Biochim Biophys Acta 1768:354-65. 2007
    ..a comprehensive study of the structural properties of saturated lipid bilayers, DPPC and DPPE, near the main phase transition. Though the chemical structure of DPPC and DPPE are largely similar (they only differ in the choline and ..
  9. ncbi Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles
    Tobias Baumgart
    School of Applied and Engineering Physics and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA
    Proc Natl Acad Sci U S A 104:3165-70. 2007
    ..Thus, GPMVs now provide an effective approach to characterize biological membrane heterogeneities...
  10. ncbi Structure of fully hydrated fluid phase lipid bilayers with monounsaturated chains
    Norbert Kucerka
    Physics Department, Carnegie Mellon University, Pittsburgh, Pennsylvania, 15213, USA
    J Membr Biol 208:193-202. 2005
    ..Our results suggest that lipids with one monounsaturated chain have quantitative bilayer structures closer to lipids with two monounsaturated chains than to lipids with two completely saturated chains...
  11. ncbi Domain formation in sphingomyelin/cholesterol mixed membranes studied by spin-label electron spin resonance spectroscopy
    M Isabel Collado
    , , Apartado 644, E-48080 Bilbao, Spain
    Biochemistry 44:4911-8. 2005
    ....
  12. ncbi Calcium triggered L alpha-H2 phase transition monitored by combined rapid mixing and time-resolved synchrotron SAXS
    Anan Yaghmur
    Institute of Biophysics and Nanosystems Research, Austrian Academy of Sciences, Graz, Austria
    PLoS ONE 3:e2072. 2008
    ....
  13. ncbi A thermally induced phase transition in a viral capsid transforms the hexamers, leaving the pentamers unchanged
    James F Conway
    Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA
    J Struct Biol 158:224-32. 2007
    ..Pentamers, on the other hand, are more stably anchored and resist this thermal perturbation...
  14. ncbi Insight into the putative specific interactions between cholesterol, sphingomyelin, and palmitoyl-oleoyl phosphatidylcholine
    Jussi Aittoniemi
    Laboratory of Physics and Helsinki Institute of Physics, Helsinki University of Technology, Helsinki, Finland
    Biophys J 92:1125-37. 2007
    ..This implies improved Chol-induced ordering of PSM's chains over POPC's chains. These findings are discussed in the context of the hydrophobic mismatch concept suggested recently...
  15. ncbi Adsorption of polar lipids at the water-oil interface
    P Reis
    Nestle Research Center, CH 1000 Lausanne 26, Switzerland
    Langmuir 24:5781-6. 2008
    ..The pH dependency of the interfacial activity of fatty acids is also explored in the current work. We believe that our results can contribute to a better understanding of the complex interfacial phenomena occurring during fat digestion...
  16. ncbi Effect of a sodium ion on the dehydration-induced phase transition of monoclinic lysozyme crystals
    Kazuaki Harata
    Biological Information Research Center, National Institute of Advanced Industrial Science and Technology AIST, Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Acta Crystallogr D Biol Crystallogr 63:1016-21. 2007
    ..This crystal-to-crystal phase transition was accompanied by 20-40% solvent loss and the transformed crystal diffracted to prominently high resolution...
  17. ncbi Cholesterol-phospholipid association in fluid bilayers: a thermodynamic analysis from nearest-neighbor recognition measurements
    Jianbing Zhang
    Department of Chemistry, Lehigh University, Bethlehem, Pennsylvania 18015, USA
    Biophys J 91:1402-6. 2006
    ..38 kcal/mol of phospholipid and DeltaS degrees = +1.68 +/- 1.12 cal/K mol of phospholipid. In the liquid-disordered/liquid-ordered coexistence region, changes in lipid mixing reflect changes in the phase composition of the membrane...
  18. ncbi Surface dilational rheology of mixed beta-lactoglobulin/surfactant layers at the air/water interface
    R Miller
    Max Planck Institut fur Kolloid und Grenzflachenforschung, Am Muhlenberg 1, 14424 Potsdam, Germany
    J Phys Chem B 109:13327-31. 2005
    ....
  19. ncbi Temperature and composition dependence of the interaction of delta-lysin with ternary mixtures of sphingomyelin/cholesterol/POPC
    Antje Pokorny
    Department of Chemistry and Biochemistry, University of North Carolina-Wilmington, Wilmington, NC, USA
    Biophys J 91:2184-97. 2006
    ..These results were combined with differential scanning calorimetry to obtain the BSM/Chol/POPC phase diagram as a function of temperature...
  20. ncbi Simultaneous phase transition of ELP tagged molecules and free ELP: an efficient and reversible capture system
    Xin Ge
    Department of Chemical Engineering, McMaster University, Ontario, Canada
    Biomacromolecules 7:2475-8. 2006
    ..In a more general context, the concept presented in this paper provides a method that is highly efficient, specific, and fully reversible, which should render it useful in areas other than recombinant protein purification...
  21. ncbi Thermotropic phase transition in soluble nanoscale lipid bilayers
    Ilia G Denisov
    Departments of Biochemistry and Chemistry, College of Medicine, and Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, 505 South Goodwin Avenue, Urbana, Illinois 61801, USA
    J Phys Chem B 109:15580-8. 2005
    The role of lipid domain size and protein-lipid interfaces in the thermotropic phase transition of dipalmitoylphosphatidylcholine (DPPC) and dimyristoylphosphatidylcholine (DMPC) bilayers in Nanodiscs was studied using small-angle X-ray ..
  22. ncbi Calorimetric, x-ray diffraction, and spectroscopic studies of the thermotropic phase behavior and organization of tetramyristoyl cardiolipin membranes
    Ruthven N A H Lewis
    Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada
    Biophys J 92:3166-77. 2007
    ..data indicate that the lower temperature transition corresponds to a lamellar subgel (L(c)') to gel (L(beta)) phase transition and the higher temperature endotherm to a L(beta) to lamellar liquid-crystalline (L(alpha)) phase transition...
  23. ncbi Reversible phase transitions in emulsified nanostructured lipid systems
    Liliana de Campo
    Institute of Chemistry, Colloids and Polymers, University of Graz, Graz, Austria
    Langmuir 20:5254-61. 2004
    ..This agreement is independent of any thermal history (including phase transitions), which proves that the structures in the dispersed particles actually are in thermodynamic equilibrium with the surrounding water phase...
  24. ncbi Condensed complexes in vesicles containing cholesterol and phospholipids
    Arun Radhakrishnan
    Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390 9046, USA
    Proc Natl Acad Sci U S A 102:12662-6. 2005
    ..Model calculations of phospholipid order parameters account for several features of the deuterium NMR spectra of labeled phospholipid molecules in bilayer mixtures with cholesterol...
  25. ncbi How principles of domain formation in model membranes may explain ambiguities concerning lipid raft formation in cells
    Erwin London
    Department of Biochemistry and Cell Biology, Stony Brook University, S U N Y, Stony Brook, NY 11794 5215, USA
    Biochim Biophys Acta 1746:203-20. 2005
    ..Very high concentrations of membrane cholesterol and proteins may explain key physical characteristics of domains in cellular membranes, and are the two of the most obvious factors requiring additional study...
  26. ncbi An intracellular lamellar-nonlamellar phase transition rationalizes the superior performance of some cationic lipid transfection agents
    Rumiana Koynova
    Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, IL 60208, USA
    Proc Natl Acad Sci U S A 103:14373-8. 2006
    ..at 45:20:20:15 (wt/wt)]; in contrast, the unsaturated C18:1/C10-EPC exhibited a lamellar-nonlamellar phase transition in such mixtures, which took place at physiological temperatures, approximately 37 degrees C...
  27. ncbi Sphingomyelin structure influences the lateral diffusion and raft formation in lipid bilayers
    Andrey Filippov
    Department of Biophysical Chemistry, , Ume, Sweden
    Biophys J 90:2086-92. 2006
    ..The results indicate that a crucial element in the domain-forming process is the formation of highly packed bilayers of SM and cholesterol rather than specific interactions between SM and cholesterol...
  28. ncbi How much solute is needed to inhibit the fluid to gel membrane phase transition at low hydration?
    Thomas Lenné
    Applied Physics, School of Applied Sciences, RMIT University, Melbourne, Australia
    Biochim Biophys Acta 1768:1019-22. 2007
    We present a quantitative study of the effect of sugars on the membrane gel-fluid phase transition as a function of sugar:lipid ratio. We show that the maximum effect occurs at around 1...
  29. ncbi Sphingomyelin-cholesterol domains in phospholipid membranes: atomistic simulation
    Sagar A Pandit
    Department of Biological, Chemical, and Physical Sciences, Illinois Institute of Technology, Chicago, Illinois 60616, USA
    Biophys J 87:1092-100. 2004
    ..The calculated difference in thickness is consistent with data obtained in atomic force microscopy experiments...
  30. ncbi Kinetics and thermodynamics of association of a phospholipid derivative with lipid bilayers in liquid-disordered and liquid-ordered phases
    Magda S C Abreu
    Departamento de Quimica, Universidade de Coimbra, Coimbra, Portugal
    Biophys J 87:353-65. 2004
    ....
  31. ncbi Fluorescence energy transfer reveals microdomain formation at physiological temperatures in lipid mixtures modeling the outer leaflet of the plasma membrane
    John R Silvius
    Department of Biochemistry, McGill University, Montreal, Quebec H3G 1Y6, Canada
    Biophys J 85:1034-45. 2003
    ....
  32. ncbi Sphingomyelin/phosphatidylcholine/cholesterol phase diagram: boundaries and composition of lipid rafts
    Rodrigo F M de Almeida
    , , , Lisbon, Portugal
    Biophys J 85:2406-16. 2003
    ..The diagrams here described are used to rationalize literature results, some of them apparently discrepant, and to discuss lipid rafts within the framework of liquid-ordered/liquid-disordered phase coexistence...
  33. ncbi Effect of potassium perfluorooctanesulfonate, perfluorooctanoate and octanesulfonate on the phase transition of dipalmitoylphosphatidylcholine (DPPC) bilayers
    W Xie
    The University of Iowa, Department of Occupational and Environmental Health, 100 Oakdale Campus 221 IREH, Iowa City, IA 52242 5000, USA
    Biochim Biophys Acta 1768:1299-308. 2007
    ..In the fluorescence experiments a linear depression of the main phase transition temperature of DPPC (T(m)) and an increased peak width was observed with increasing concentration of all ..
  34. ncbi Liquid-liquid phase transition in supercooled silicon
    Srikanth Sastry
    Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur Campus, Bangalore 560064, India
    Nat Mater 2:739-43. 2003
    ....
  35. ncbi Effects of cholesterol on physical properties of human erythrocyte membranes: impact on susceptibility to hydrolysis by secretory phospholipase A2
    Anne L Heiner
    Department of Physiology and Developmental Biology, Brigham Young University, Provo, Utah 84602, USA
    Biophys J 94:3084-93. 2008
    ..It is also proposed that the high level of cholesterol in erythrocyte membranes is a protective mechanism to guard against hydrolytic enzymes...
  36. ncbi Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol
    Sarah L Veatch
    Departments of Chemistry and Physics, University of Washington, Seattle, Washington 98195-1700, USA
    Biophys J 85:3074-83. 2003
    ..To date, we have not observed macroscopic separation of liquid phases in only binary lipid mixtures...
  37. ncbi Gradual change or phase transition: characterizing fluid lipid-cholesterol membranes on the basis of thermal volume changes
    Heiko Heerklotz
    Biozentrum der Universitat Basel, Division of Biophysical Chemistry, CH 4056 Basel, Switzerland
    Biophys J 91:600-7. 2006
    ..Accordingly, one cholesterol may condense 3 +/- 1 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine molecules by approximately -(1.4 +/- 0.5) vol % at 2 degrees C; both absolute values decrease with increasing temperature...
  38. ncbi Quantitative CARS spectroscopy using the maximum entropy method: the main lipid phase transition
    Hilde A Rinia
    Swammerdam Institute for Life Sciences, University of Amsterdam, P O Box 94062, 1090 GB Amsterdam, The Netherlands
    Chemphyschem 8:279-87. 2007
    ..CARS) spectra is described in detail and applied to the time-resolved measurement of the main lipid phase transition of small, unilamellar 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) vesicles subject to a 3 min ..
  39. ncbi Lipid lateral diffusion in ordered and disordered phases in raft mixtures
    Andrey Filippov
    Department of Biophysical Chemistry, , SE-901 87 Ume, Sweden
    Biophys J 86:891-6. 2004
    ..This means that on the millisecond timescale fluid, ordered domains are floating around in a sea of faster diffusing lipids, assigned to consist of mainly dioleoylphosphatidylcholine...
  40. ncbi Evidence for the lack of a specific interaction between cholesterol and sphingomyelin
    Juha M Holopainen
    Helsinki Biophysics and Biomembrane Group, Institute of Biomedicine, University of Helsinki, Finland
    Biophys J 86:1510-20. 2004
    ..In DNPC below the main phase transition, the addition of up to 5 mol % cholesterol reduced I(e)/I(m) significantly...
  41. ncbi Rigidification of neutral lipid bilayers in the presence of salts
    Georg Pabst
    Institute of Biophysics and Nanosystems Research, Austrian Academy of Sciences, Graz, Austria
    Biophys J 93:2688-96. 2007
    ..increase of order within the lipid bilayer, leading to a decrease of bilayer elasticity and shift of main phase transition temperature. This effect is more pronounced for Ca2+, and occurs mainly in the high salt-concentration regime...
  42. ncbi Lessons of slicing membranes: interplay of packing, free area, and lateral diffusion in phospholipid/cholesterol bilayers
    Emma Falck
    Laboratory of Physics and Helsinki Institute of Physics, Helsinki University of Technology, Helsinki, Finland and Wihuri Research Institute, Helsinki, Finland
    Biophys J 87:1076-91. 2004
    ..Summarizing, our results highlight the central role of free area in comprehending the structural and dynamic properties of membranes containing cholesterol...
  43. ncbi The effect of cholesterol on the lateral diffusion of phospholipids in oriented bilayers
    Andrey Filippov
    Department of Biophysical Chemistry, , SE-90187 Ume, Sweden
    Biophys J 84:3079-86. 2003
    ..For the DOPC/CHOL and the POPC/CHOL systems no two-phase behavior were observed, and the obtained E(A):s indicate that these systems are in the l(d) phase at all CHOL contents for temperatures above 25 degrees C...
  44. ncbi Mechanism of the lamellar/inverse hexagonal phase transition examined by high resolution x-ray diffraction
    Michael Rappolt
    Institute of Biophysics and X ray Structure Research, Austrian Academy of Sciences, c o Sincrotrone Trieste, 34012 Basovizza, Italy
    Biophys J 84:3111-22. 2003
    ..During the lamellar-to-inverse hexagonal phase transition the area per lipid molecule reduces by approximately 25%, and the number of water molecules per lipid ..
  45. ncbi Formation of mesoscopic water networks in aqueous systems
    Lívia B Pártay
    Laboratory of Interfaces and Nanosize Systems, Institute of Chemistry, Eotvos Lorand University, Budapest, Hungary
    Phys Chem Chem Phys 9:1341-6. 2007
    ..Formation and topology of spanning water networks, which affect various properties of aqueous systems, can be described within the framework of the percolation theory...
  46. ncbi Multiarmed tubular selenium with potentially unique electrical properties: solution-phase synthesis and first-principles calculation
    Bin Zhang
    Department of Nanomaterials and Nanochemistry, Hefei National Laboratory for Physical Sciences at Microscale, University of Science and Technology of China, Hefei, Anhui 230026, PR China
    Small 3:101-5. 2007
  47. ncbi Simulations of edge behavior in a mixed-lipid bilayer: fluctuation analysis
    Yong Jiang
    Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA
    J Chem Phys 126:045105. 2007
    ..The estimated value of the in-plane bending modulus is of order 10(-29) J m, placing the intrinsic persistence length for the edge near the bilayer thickness of 4 nm...
  48. ncbi Thermal properties of PMMA/montmorillonite clay nanocomposites
    M A Jothi Rajan
    School of Physics, Madurai Kamaraj University, Madurai 625021, India
    J Nanosci Nanotechnol 6:3993-6. 2006
    ..An analysis of the TG, DTG curves reveal that the thermal stability is found to increase by nearly 30% for ultrasonic mixing than that of magnetic stirring...
  49. ncbi Study of rheological properties of polypropylene/organoclay hybrid materials
    Suzhu Yu
    Singapore Institute of Manufacturing Technology, 71 Nanyang Drive, Singapore 638075
    J Nanosci Nanotechnol 6:3989-92. 2006
    ..A shear thinning behavior is found for both polypropylene and its composites, but the onset of shear thinning for organoclay composites occurs at lower shear rates...
  50. ncbi Soft patchy nanoparticles from solution-phase self-assembly of binary diblock copolymers
    Goundla Srinivas
    IBM Almaden Research Center, 650 Harry Road, San Jose, California 94086, USA
    Nano Lett 8:611-8. 2008
    ..The number and size of the patches are found to be largely controlled by the composition of the binary copolymer mixture...
  51. ncbi Stress behavior of FCC metallic thin films during thermal evaporation
    Sang Ryu
    Department of Materials Science and Engineering, Chonnam National University, Gwangju 500 757, Korea
    J Nanosci Nanotechnol 7:4081-3. 2007
    ..The incremental compressive stress region may be related to surface state and atomic mobilities...
  52. ncbi A consistent model for thermal fluctuations and protein-induced deformations in lipid bilayers
    Grace Brannigan
    Department of Physics and Astronomy, University of California, Santa Barbara, California, USA
    Biophys J 90:1501-20. 2006
    ..Inclusion of a finite monolayer spontaneous curvature is essential to obtain fully consistent agreement between theory and the full range of available simulation/experimental data...
  53. ncbi Synthesis and thermal behaviour of nanostructured ZrO2 powders obtained under hydrothermal conditions
    Helen Reveron
    Ecole Nationale Supérieure de Céramique Industrielle, Limoges, France
    J Nanosci Nanotechnol 5:1643-50. 2005
    ..The effect of some experimental conditions over the colloidal particle size or zirconia phase composition was studied. The powder sintering behaviour is also presented...
  54. ncbi Self-assembly and thermal phase transition behavior of unsymmetrical bolaamphiphiles having glucose- and amino-hydrophilic headgroups
    Naohiro Kameta
    SORST, Japan Science and Technology Agency JST, and Nanoarchitectonics Research Center NARC, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba Central 5, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8565, Japan
    Langmuir 23:4634-41. 2007
    The thermal phase transition and self-assembly behaviors in water of the crystalline lamellar films prepared from unsymmetrical bolaamphiphiles, N-(2-aminoethyl)-N'-(beta-d-glucopyranosyl)-alkanediamide [1(n), n = 12, 14, 16, 17, 18, and ..
  55. ncbi Surface viscosity, diffusion, and intermonolayer friction: simulating sheared amphiphilic bilayers
    S A Shkulipa
    Computational Dispersion Rheology, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands
    Biophys J 89:823-9. 2005
    ..The second flow field, with a vorticity parallel to the bilayer, causes the two constituent monolayers to slide past one another, yielding the interlayer friction coefficient...
  56. ncbi Characterizing the nature of virtual amorphous silicon
    Devashish Choudhary
    School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, New York, 14853, USA
    J Chem Phys 122:174509. 2005
    ..Throughout this study, we have monitored the role of order in determining physical properties, as characterized by traditional routes (such as angular correlations) and more novel ones (the signature cell method)...
  57. ncbi Clathrate formation and dissociation in vapor/water/ice/hydrate systems in SBA-15, sol-gel and CPG porous media, as probed by NMR relaxation, novel protocol NMR cryoporometry, neutron scattering and ab initio quantum-mechanical molecular dynamics simulati
    J Beau W Webber
    Institute of Petroleum Engineering, Heriot Watt University, Edinburgh EH14 4AS, UK
    Magn Reson Imaging 25:533-6. 2007
    ..Ab initio quantum-mechanical molecular dynamics calculations are also being employed to probe the dynamics of liquids in pores at nanometric dimensions...
  58. ncbi Cavity growth in soft adhesives
    A Chiche
    U.M.R. 7615, , ESPCI, 10 rue Vauquelin, , France
    Eur Phys J E Soft Matter 17:389-401. 2005
    ....
  59. ncbi Effect of cobalt doping on the phase transformation of TiO2 nanoparticles
    M A Barakat
    Department of Materials Science and Engineering University of Delaware, Newark, Delaware 19716, USA
    J Nanosci Nanotechnol 5:759-65. 2005
    ..0085 to 0.085. The activation energy for the phase transformation from anatase to rutile was measured to be 229, 222, 211, and 195 kJ/mole for 0.0085, 0.017, 0.0255, and 0.034 mol % Co in TiO2, respectively...
  60. ncbi Structure of phospholipid-cholesterol membranes: an x-ray diffraction study
    Sanat Karmakar
    Raman Research Institute, Bangalore 560080, India
    Phys Rev E Stat Nonlin Soft Matter Phys 71:061924. 2005
    ..At higher cholesterol contents the gel phase does not occur in any of these three systems, and the fluid lamellar phase is observed down to the lowest temperature studied (5 degrees C)...
  61. ncbi A density-driven phase transition between semiconducting and metallic polyamorphs of silicon
    Paul F McMillan
    Department of Chemistry and Materials Chemistry Centre, Christopher Ingold Laboratories, University College London, 20 Gordon Street, London WC1H 0AJ, UK
    Nat Mater 4:680-4. 2005
    ..The experiments are combined with molecular dynamics simulations that map the behaviour of the amorphous solid on to that of the liquid state...
  62. ncbi Aqueous-phase synthesis of ultra-stable small CdSe nanoparticles
    Yeon Su Park
    Center for Interdisciplinary Research, Tohoku University, Aoba ku, Sendai 980 8578, Japan
    J Nanosci Nanotechnol 7:3750-3. 2007
    ..Under these conditions, the peaks always appear at nearly the same wavelength, indicating that these NPs are selectively stable and grow at a particular size and structure...
  63. ncbi Poly(vinyl alcohol)/silica nanocomposites: morphology and thermal degradation kinetics
    Zheng Peng
    Agriculture Ministry Key Laboratory of Natural Rubber Processing, Zhanjiang 524001, China
    J Nanosci Nanotechnol 6:3934-8. 2006
    ..However, at a given degradation temperature, the nanocomposite presents much lower reaction velocity constants (k), while its E is 20 kJ/mol higher than that of the PVA host...
  64. ncbi Anomalously slow domain growth in fluid membranes with asymmetric transbilayer lipid distribution
    Mohamed Laradji
    Department of Physics, The University of Memphis, Memphis, TN 38152, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 73:040901. 2006
    ..In contrast, in the limiting cases of high and low tensions, the dynamics proceeds toward full phase separation...
  65. ncbi Thermosensitive nanocontainers prepared from poly(N-isopropylacrylamide-co-N-(hydroxylmethyl) acrylamide)-g-poly(lactide)
    Yan Zhang
    The Key Laboratory of Molecular Engineering of Polymers, Ministry of Education, Department of macromolecular Science of Fudan University, Shanghai 200433, China
    J Nanosci Nanotechnol 6:2896-901. 2006
    ..In particular it will combine a spatial specificity in a passive manner and a temperature-responsive active targeting mechanism for drug delivery system...
  66. ncbi Complex buckling instability patterns of nanomembranes with encapsulated gold nanoparticle arrays
    Chaoyang Jiang
    Department of Materials Science and Engineering, Iowa State University, Ames, Iowa 50011, USA
    Nano Lett 6:2254-9. 2006
    ..The binary buckling pattern observed here allowed the "one-shot" evaluation of the elastic moduli of two compositionally different regions (with and without gold nanoparticles)...
  67. ncbi Temperature dependence of structure, bending rigidity, and bilayer interactions of dioleoylphosphatidylcholine bilayers
    Jianjun Pan
    Department of Physics, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Biophys J 94:117-24. 2008
    ....
  68. ncbi Diameter-dependent composition of vapor-liquid-solid grown Si(1-x)Ge(x) nanowires
    Xi Zhang
    Department of Materials Science and Engineering, Materials Research Institute, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Nano Lett 7:3241-5. 2007
    ..The size-dependent nature of Ge concentration in Si(1-x)Ge(x) NWs is strongly suggestive of Gibbs-Thomson effects and highlights another important phenomenon in nanowire growth...
  69. ncbi Effect of material properties of composite restoration on the strength of the restoration-dentine interface due to polymerization shrinkage, thermal and occlusal loading
    Krzysztof Borkowski
    School of Mechanical Engineering, The University of Adelaide, SA 5005, Australia
    Med Eng Phys 29:671-6. 2007
    ....
  70. ncbi Role of nonadditive forces on the structure and properties of liquid water
    Jianhui Li
    Centre for Molecular Simulation, Swinburne University of Technology, P O Box 218, Hawthorn, Victoria 3122, Australia
    J Chem Phys 127:154509. 2007
    ..It also predicts the relative contribution of hydrogen bonding better than the SPC/E potential [Berendsen et al., J. Phys. Chem. 91, 6269 (1987)]...
  71. ncbi Radius and chirality dependent conformation of polymer molecule at nanotube interface
    Chenyu Wei
    MS 229 1, NASA Ames Research Center, Moffett Field, California 94035, USA
    Nano Lett 6:1627-31. 2006
    ..A nematic transformation around 280 K is identified through the Landau-de Gennes theory, with molecule aligning along tube axis in extended conformations...
  72. ncbi The role of thickness transitions in convective assembly
    Linli Meng
    Department of Chemical Engineering and Materials Science, University of Minnesota, 421 Washington Avenue SE, Minneapolis, Minnesota 55455, USA
    Nano Lett 6:2249-53. 2006
    ..In thicker crystals, the crystallization is more complicated, but the transition regions must still be considered before a complete understanding of convective assembly can be obtained...
  73. ncbi Orientational order in block copolymer films zone annealed below the order--disorder transition temperature
    Brian C Berry
    Polymers Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8541, USA
    Nano Lett 7:2789-94. 2007
    ..The ability to rapidly process polymers with inaccessible order-disorder transition temperatures suggests zone annealing as a route toward more robust nanomanufacturing methods based on block copolymer self-assembly...
  74. ncbi Full q-space analysis of x-ray scattering of multilamellar membranes at liquid-solid interfaces
    Da-Peng Li
    Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080, China
    Phys Rev E Stat Nonlin Soft Matter Phys 73:031916. 2006
    ..The theoretical apparatus is successfully applied to the experimental data on DOPC membranes...
  75. ncbi Bonding nature and structural phase transition in fullerene based nanomaterials
    Dam Hieu Chi
    Japan Advanced Institute of Science and Technology, Tatsunokuchi, Ishikawa 923-1292, Japan
    J Nanosci Nanotechnol 6:3888-92. 2006
    ..The derived charge density map indicates that the transitions can be regarded as reversible structural changes from fullerene dimers to monomers. These features are ascribed to the unique bonding nature of rare-earth C70 compounds...
  76. ncbi Morphology of a highly asymmetric double crystallizable poly(epsilon-caprolactone-b-ethylene oxide) block copolymer
    Liangbin Li
    National Synchrotron Radiation Laboratory, University of Science and Technology of China, Anhui 230026, China
    J Chem Phys 126:024904. 2007
    ..This implies a similar underlying mechanism of coupling and competition of various phase transitions, which is worth further exploration...
  77. ncbi Studying nanoparticles in-flight: applications of size-selected free nanoparticles
    F E Kruis
    Nanostrukturtechnik, Fakultät für Ingenieurwissenschaften, Universitat Duisburg Essen, 47048 Duisburg, Germany
    J Nanosci Nanotechnol 7:1703-11. 2007
    ..05...
  78. ncbi Uniaxial alignment of nanoconfined columnar mesophases
    Pierre Olivier Mouthuy
    Cermin, Universite Catholique de Louvain, 1348 Louvain la Neuve, Belgium
    Nano Lett 7:2627-32. 2007
    ..Preferential mesophase alignment results from this nonhomogeneity combined with the anisotropy of the network cell dimensions. A simple model is proposed to explain the experimental observations...
  79. ncbi Faceting and stability of smectic A droplets on a solid substrate
    P Oswald
    Laboratoire de Physique, Ecole Normale Superieure de Lyon, 69364, Lyon Cedex 07, France
    Eur Phys J E Soft Matter 19:441-52. 2006
    ..part of the droplet are determined as a function of the temperature in the vicinity of a nematic-smectic A phase transition. It is shown that the observed profiles do not correspond to the actual equilibrium shape, but to metastable ..
  80. ncbi Controlled arrangement of nanoparticle arrays in block-copolymer domains
    Agus Haryono
    Indonesian Institute of Sciences (LIPI, Research Center for Chemistry, Polymer Chemistry Group, Kawasan Puspiptek Serpong, 15314 Tangerang, Indonesia
    Small 2:600-11. 2006
    ..Furthermore, examples on applications and technological aspects of the resulting nanoparticle/polymer nanocomposites are provided...
  81. ncbi From designer clusters to synthetic crystalline nanoassemblies
    A Welford Castleman
    Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Nano Lett 7:2734-41. 2007
    ..The new compound has a significantly larger band gap than the hitherto known solid. Thus, our approach allows the tuning of the electronic properties of solid cluster assemblies...
  82. ncbi Simulation of the pressure-driven wurtzite to rock salt phase transition in nanocrystals
    Benjamin J Morgan
    School of Chemistry, Trinity College, University of Dublin, Dublin 2, Ireland
    Phys Chem Chem Phys 8:3304-13. 2006
    ....
  83. ncbi Main phase transitions in supported lipid single-bilayer
    A Charrier
    Centre de Recherche en Matière Condensée et Nanosciences, Centre National de la Recherche Scientifique, Universite de la Mediterranee, Marseille, France
    Biophys J 89:1094-101. 2005
    ..The experimental data can be fit with such a model using known thermodynamic parameters...
  84. ncbi Molecular dynamics in nanophase-separated comb-like poly(alpha-n-alkyl beta-L-aspartate)s
    M Grimau
    Materials Science Department, Universidad Simon Bolivar, Apartado 89000, Caracas 1080, Venezuela
    Eur Phys J E Soft Matter 15:383-93. 2004
    ..The restricted chopstick motion of the rigid rods is thought to be the origin of the alpha mode; this motion is hindered at temperatures where the cage size decreases as a result of the increasing disorder with temperature...
  85. ncbi Crystal form and phase structure of poly(vinylidene fluoride)/polyamide 11/clay nanocomposites by high-shear processing
    Yongjin Li
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba Central 5, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8565, Japan
    J Nanosci Nanotechnol 8:1714-20. 2008
    ..Moreover, the addition of organoclay shows significant effects on the phase structure of PVDF/PA11 blends...
  86. ncbi Molecular view of hexagonal phase formation in phospholipid membranes
    Siewert Jan Marrink
    Department of Biophysical Chemistry, University of Groningen, 9747 AG Groningen, The Netherlands
    Biophys J 87:3894-900. 2004
    ..The rate of stalk elongation is approximately 0.1 nm ns(-1). Within a narrow hydration/temperature/composition range the stalks appear stable and rearrange into the rhombohedral phase...
  87. ncbi Coupling field theory with mesoscopic dynamical simulations of multicomponent lipid bilayers
    J Liam McWhirter
    Department of Chemistry and Henry Eyring Center for Theoretical Chemistry, University of Utah, Salt Lake City, Utah 84112-0850, USA
    Biophys J 87:3242-63. 2004
    ..This response, measured in the mesoscopic regime, is already known to be conditioned or renormalized by thermal undulations...
  88. ncbi Instabilities and pattern miniaturization in confined and free elastic-viscous bilayers
    Dipankar Bandyopadhyay
    Department of Chemical Engineering, Indian Institute of Technology, Kanpur, India
    J Chem Phys 128:154909. 2008
    ..These findings may have potential applications in the self-organized patterning of soft materials...
  89. ncbi Structural characterization of room-temperature synthesized nano-sized beta-tricalcium phosphate
    Jong-Shing Bow
    QA12A/FA of United Microelectronics Cooperation, Tainan 744, Taiwan, Republic of China
    Biomaterials 25:3155-61. 2004
    ....
  90. ncbi Partitioning of pyrene-labeled phospho- and sphingolipids between ordered and disordered bilayer domains
    Mirkka Koivusalo
    Institute of Biomedicine, Department of Biochemistry, University of Helsinki, Helsinki, Finland
    Biophys J 86:923-35. 2004
    ..We conclude that pyrene-labeled lipids could be valuable tools when monitoring domain formation in model and biological membranes as well as when assessing the role of membrane domains in lipid trafficking and sorting...
  91. ncbi Effects of physiological environments on the hydration behavior of mineral trioxide aggregate
    Yuan-Ling Lee
    School of Dentistry, College of Medicine, National Taiwan University, Chang Te Street, Taipei 10016, Taiwan, ROC
    Biomaterials 25:787-93. 2004
    ..In particular, an acidic environment of pH 5 adversely affects both the physical properties and the hydration behavior of MTA...
  92. ncbi Molecular simulation study of phospholipid bilayers and insights of the interactions with disaccharides
    Amadeu K Sum
    Department of Chemical Engineering, University of Wisconsin, Madison, Wisconsin, USA
    Biophys J 85:2830-44. 2003
    ....
  93. ncbi Interaction between artificial membranes and enflurane, a general volatile anesthetic: DPPC-enflurane interaction
    Nathalie Hauet
    , UMR 8612, , , France
    Biophys J 84:3123-37. 2003
    ..All the results taken together allowed to draw a pseudo-binary phase diagram of enflurane-dipalmitoylphosphatidylcholine in excess water...
  94. ncbi Direct imaging and mesoscale modelling of phase transitions in a nanostructured fluid
    A Knoll
    Physikalische Chemie II, , D-95440 Bayreuth, Germany
    Nat Mater 3:886-91. 2004
    ..Our movies based on in situ scanning force microscopy show the time sequence of the elementary steps of a phase transition in a fluid film of block copolymer from the cylinder to the perforated lamella phase...
  95. ncbi Cooperativity and kinetics of phase transitions in nanopore-confined bilayers studied by differential scanning calorimetry
    Ali M Alaouie
    Biophys J 88:L11-3. 2005
    The first-order nature of the gel-to-liquid crystal phase transition of phospholipid bilayers requires very slow temperature rates in differential scanning calorimetry (DSC) experiments to minimize any rate-dependent distortions...
  96. ncbi Finite-size effects in biomimetic smectic films
    T A Harroun
    Steacie Institute for Molecular Sciences, National Research Council, Chalk River, Ontario, Canada K0J 1J0
    Phys Rev E Stat Nonlin Soft Matter Phys 70:062902. 2004
    ..Various scenarios that may be responsible for this counterintuitive observation are discussed...
  97. ncbi Surface phase partitioning in film formation of waterborne polyurethanes. Monte Carlo simulations and internal-reflectance IR imaging
    R B Pandey
    Department of Physics and Astronomy and School of Polymers and High Performance Materials, The University of Southern Mississippi, Hattiesburg, Mississippi 39406, USA
    Langmuir 20:2970-4. 2004
  98. ncbi Static and dynamic heterogeneities in water
    H Eugene Stanley
    Center for Polymer Studies and Department of Physics, Boston University, Boston, MA 02215, USA
    Philos Trans A Math Phys Eng Sci 363:509-23. 2005
    ..In respect to static heterogeneities, this local geometry is critical. The dynamic behaviour of water seems to be related to dynamic heterogeneities, which seem to explain the dynamics of supercooled liquid water well...
  99. ncbi A 'first principles' potential energy surface for liquid water from VRT spectroscopy of water clusters
    Nir Goldman
    Lawrence Livermore National Laboratory, Chemistry and Materials Science Directorate, L-268, Livermore, CA 94551, USA
    Philos Transact A Math Phys Eng Sci 363:493-508. 2005
    ..The results herein represent the first time to the authors' knowledge that a 'spectroscopic' potential surface is able to correctly model condensed phase properties of water...
  100. ncbi Stalk phase formation: effects of dehydration and saddle splay modulus
    Yonathan Kozlovsky
    Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Biophys J 87:2508-21. 2004
    ..We suggest that fusion proteins can induce stalk formation just by bringing the membranes into close contact, and accumulating, at least locally, a sufficiently large energy of the hydration repulsion...
  101. ncbi Temperature-dependent phase stability of nanocrystalline SiO2
    Sampa Dhabal
    Department of Physics and Meteorology, Indian Institute of Technology, Kharagpur--721302, India
    J Nanosci Nanotechnol 4:1067-70. 2004
    ..Annealing at higher temperatures, the amorphous phase gradually transforms into small crystallites of alpha-crystobalite. Subsequently, the tiny crystallites form small domains in the structural form of beta-crystobalite...

Research Grants77

  1. Monoclonal antibodies to inhibit Aspergillus germination
    Marta Feldmesser; Fiscal Year: 2009
    ..interactions in invasive aspergillosis using a monoclonal antibody (MAb 318) that inhibits germination, the phase transition from the spore form to hyphal form that is required for invasion, and prolongs survival in mice with invasive ..
  2. Replication licensing and cell cycle checkpoints
    Jeanette Gowen Cook; Fiscal Year: 2010
    ..is stimulated by the activity of cyclin dependent protein kinases (Cdks) that are activated at the G1/S phase transition and remain active until mitosis...
  3. Replication licensing and cell cycle checkpoints
    JEANETTE COOK; Fiscal Year: 2009
    ..is stimulated by the activity of cyclin dependent protein kinases (Cdks) that are activated at the G1/S phase transition and remain active until mitosis...
  4. TESTOSTERONE REPLACEMENT & PHYSICAL FUNCTION IN HIV+MEN
    Shalender Bhasin; Fiscal Year: 2005
    ..mass; we will determine whether testosterone supplementation increases satellite cell number by promoting G:S phase transition, thus inducing satellite cells to enter the cell cycle or by inhibiting satellite cell apoptosis...
  5. HYPERTHERMIA AND PERFUSION EFFECTS IN CANCER THERAPY
    Mark Dewhirst; Fiscal Year: 2007
    ..drugs, particularly with novel thermolabile liposomes that release contents within seconds of reaching their phase transition temperature, (3) conduct phase III trials comparing best conventional therapy q HT, (4) examine whether ..
  6. Multiplex Nanocarrier-based Hydrogels for Prevention of Vaginal HIV Transmission.
    Patrick Sinko; Fiscal Year: 2009
    ..upon instillation allowing for high vaginal dispersion/mucosal coverage where it then undergoes a rapid phase transition to form a visco-elastic gel...
  7. Multiplex Nanocarrier-based Hydrogels for Prevention of Vaginal HIV Transmission.
    Patrick J Sinko; Fiscal Year: 2010
    ..upon instillation allowing for high vaginal dispersion/mucosal coverage where it then undergoes a rapid phase transition to form a visco-elastic gel...
  8. Jun Kinase Signaling and Apoptosis in Ischemia Stroke
    Chia Yi Kuan; Fiscal Year: 2006
    ..The cellular mechanisms that may abolish the G1/S-phase transition block in cerebral ischemia will be examined...
  9. A novel vaccine/adjuvant for Streptococcus pneumoniae
    M A Westerink; Fiscal Year: 2003
    ..F127-based matrices are characterized by reverse thermogelation, a feature that allows a phase transition from liquid to gel upon reaching physiological temperatures...
  10. ASSEMBLY AND FUNCTION OF THE U4/U6 SPLICEOSOMAL SNRNP
    DAVID BROW; Fiscal Year: 2000
    ..in the splicing factor Prp8, one of the subjects of this study, result in cell cycle arrest at the G1/S phase transition. Since loss of cell cycle regulation plays a major role in tumor progression, detailed knowledge of the ..
  11. Monoclonal antibodies to inhibit Aspergillus germination
    Marta Feldmesser; Fiscal Year: 2007
    ..interactions in invasive aspergillosis using a monoclonal antibody (MAb 318) that inhibits germination, the phase transition from the spore form to hyphal form that is required for invasion, and prolongs survival in mice with invasive ..
  12. Monoclonal antibodies to inhibit Aspergillus germination
    MARTA L FELDMESSER; Fiscal Year: 2010
    ..interactions in invasive aspergillosis using a monoclonal antibody (MAb 318) that inhibits germination, the phase transition from the spore form to hyphal form that is required for invasion, and prolongs survival in mice with invasive ..
  13. Cell Cycle Regulation of Histone Gene Expression
    Gary S Stein; Fiscal Year: 2010
    ..The controlled activation of histone gene expression at the G1/S phase transition is essential for chromatin packaging of nascent DNA...
  14. Swellable Templated Copolymers
    RUDOLF SEITZ; Fiscal Year: 2006
    ..The rest is N-isopropylacrylamide or n-propylacrylamide. This polymer undergoes a thermal phase transition, coming out of solution above the thermal phase transition temperature...
  15. Oxidative Stess and Heart Failure by Copper Restriction
    Y Kang; Fiscal Year: 2004
    ..examine the role of atrial natriuretic peptide (ANP) and tumor necrosis factor-alpha (TNF-alpha) in the late phase transition from heart hypertrophy to failure, dynamic changes in ANP and TNF-alpha production will be studied...
  16. Molecular Mechanisms that Regulate Phase Transition in Dimorphic Fungi
    GREGORY GAUTHIER; Fiscal Year: 2007
    ..the pivotal role of morphogenesis in pathogenesis of these infections, the mechanisms that regulate the phase transition are poorly understood...
  17. Thermally targeted drug delivery by elastin biopolymers
    Ashutosh Chilkoti; Fiscal Year: 2009
    ..project period that a systemically administered ELP that was designed to undergo a hydrophilic-hydrophobic phase transition at 40 oC (ELPactive) formed micron size aggregates that adhered to the vasculature of tumors that were heated ..
  18. Molecular Mode of Action of JAB-1 in Cell Proliferation
    FRANCOIS CLARET; Fiscal Year: 2006
    ..p27 plays an important role in the regulation of the G1 to S phase transition. Thus, an improved comprehension of the mechanisms regulating p27 expression and function could contribute to ..
  19. Thermally targeted drug delivery by elastin biopolymers
    Ashutosh Chilkoti; Fiscal Year: 2010
    ..project period that a systemically administered ELP that was designed to undergo a hydrophilic-hydrophobic phase transition at 40 oC (ELPactive) formed micron size aggregates that adhered to the vasculature of tumors that were heated ..
  20. Thermally targeted drug delivery by elastin biopolymers
    Ashutosh Chilkoti; Fiscal Year: 2007
    ..project period that a systemically administered ELP that was designed to undergo a hydrophilic-hydrophobic phase transition at 40 oC (ELPactive) formed micron size aggregates that adhered to the vasculature of tumors that were heated ..
  21. INTERMEDIATES AND TRANSBILAYER PEPTIDES
    Martin Caffrey; Fiscal Year: 2001
    ..fusion intermediates exist under special circumstances in systems undergoing the bilayer/inverted hexagonal phase transition. In this study Dr...
  22. Agnoprotein in JC virus virion biogenesis and replication
    Mahmut Safak; Fiscal Year: 2009
    ..It deregulates cell cycle progression, in which agnoprotein positive cells largely accumulate at G2/M phase transition. We also demonstrated the involvement of the coding region of agnoprotein in regulation of JCV life cycle by ..
  23. Cables role in endometrial differentiation and cancer
    Bo Rueda; Fiscal Year: 2007
    ..Cdk2 regulates the G1 S-phase transition of the cell cycle and cdk2 tyrosine phosphorylation is inhibitory and leads to decreased cdk2 activity and ..