acceleration

Summary

Top Publications

  1. ncbi Conducting accelerometer-based activity assessments in field-based research
    Stewart G Trost
    Community Health Institute, Kansas State University, Manhattan, KS 66506, USA
    Med Sci Sports Exerc 37:S531-43. 2005
  2. ncbi Accelerometry: a technique for quantifying movement patterns during walking
    Justin J Kavanagh
    School of Physiotherapy and Exercise Science, Griffith University, Gold Coast Campus, PMB 50 Gold Coast Mail Centre, Queensland 9726, Australia
    Gait Posture 28:1-15. 2008
  3. ncbi A triaxial accelerometer and portable data processing unit for the assessment of daily physical activity
    C V Bouten
    University of Technology, Division of Computational and Experimental Mechanics, Eindhoven, The Netherlands
    IEEE Trans Biomed Eng 44:136-47. 1997
  4. ncbi Sources of variance in daily physical activity levels as measured by an accelerometer
    Charles E Matthews
    Department of Epidemiology and Biostatistics, Norman J Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
    Med Sci Sports Exerc 34:1376-81. 2002
  5. ncbi Implementation of a real-time human movement classifier using a triaxial accelerometer for ambulatory monitoring
    Dean M Karantonis
    Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia
    IEEE Trans Inf Technol Biomed 10:156-67. 2006
  6. ncbi Accelerometer-determined steps per day in US adults
    Catrine Tudor-Locke
    Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Med Sci Sports Exerc 41:1384-91. 2009
  7. pmc A review of accelerometry-based wearable motion detectors for physical activity monitoring
    Che Chang Yang
    Department of Mechanical Engineering, Yuan Ze University 135, Yuan Tung Rd, Chung Li, 32003, Taiwan
    Sensors (Basel) 10:7772-88. 2010
  8. pmc Tri-axial dynamic acceleration as a proxy for animal energy expenditure; should we be summing values or calculating the vector?
    Lama Qasem
    Biological Sciences, College of Science, Swansea University, Swansea, Wales, United Kingdom
    PLoS ONE 7:e31187. 2012
  9. pmc The origin of modern frogs (Neobatrachia) was accompanied by acceleration in mitochondrial and nuclear substitution rates
    Iker Irisarri
    Department of Biodiversity and Evolutionary Biology, Museo Nacional de Ciencias Naturales, CSIC, Jose Gutierrez Abascal 2, 28006, Madrid, Spain
    BMC Genomics 13:626. 2012
  10. ncbi Acceleration patterns of the head and pelvis when walking are associated with risk of falling in community-dwelling older people
    Hylton B Menz
    Prince of Wales Medical Research Institute, University of New South Wales, High Street, Randwick, NSW 2031, Australia
    J Gerontol A Biol Sci Med Sci 58:M446-52. 2003

Detail Information

Publications354 found, 100 shown here

  1. ncbi Conducting accelerometer-based activity assessments in field-based research
    Stewart G Trost
    Community Health Institute, Kansas State University, Manhattan, KS 66506, USA
    Med Sci Sports Exerc 37:S531-43. 2005
    ..The purpose of this review is to address important methodological issues related to conducting accelerometer-based assessments of physical activity in free-living individuals...
  2. ncbi Accelerometry: a technique for quantifying movement patterns during walking
    Justin J Kavanagh
    School of Physiotherapy and Exercise Science, Griffith University, Gold Coast Campus, PMB 50 Gold Coast Mail Centre, Queensland 9726, Australia
    Gait Posture 28:1-15. 2008
    ..the use of accelerometer technology to investigate gait-related movement patterns, and addresses issues of acceleration measurement important for experimental design...
  3. ncbi A triaxial accelerometer and portable data processing unit for the assessment of daily physical activity
    C V Bouten
    University of Technology, Division of Computational and Experimental Mechanics, Eindhoven, The Netherlands
    IEEE Trans Biomed Eng 44:136-47. 1997
    ..and can be used to register accelerations covering the amplitude and frequency ranges of human body acceleration. Interinstrument and test-retest experiments showed that the offset and the sensitivity of the TA were equal ..
  4. ncbi Sources of variance in daily physical activity levels as measured by an accelerometer
    Charles E Matthews
    Department of Epidemiology and Biostatistics, Norman J Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
    Med Sci Sports Exerc 34:1376-81. 2002
    ..To examine sources of variance in objective measures of physical activity in a group of healthy adults (N = 92) participating in a physical activity measurement study...
  5. ncbi Implementation of a real-time human movement classifier using a triaxial accelerometer for ambulatory monitoring
    Dean M Karantonis
    Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia
    IEEE Trans Inf Technol Biomed 10:156-67. 2006
    ..3% accuracy), and detection of possible falls was made with 95.6% accuracy. Results demonstrate the feasibility of implementing an accelerometry-based, real-time movement classifier using embedded intelligence...
  6. ncbi Accelerometer-determined steps per day in US adults
    Catrine Tudor-Locke
    Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Med Sci Sports Exerc 41:1384-91. 2009
    ..This accelerometer is known to have a lower sensitivity threshold than accepted pedometers, leading to relatively higher step estimates...
  7. pmc A review of accelerometry-based wearable motion detectors for physical activity monitoring
    Che Chang Yang
    Department of Mechanical Engineering, Yuan Ze University 135, Yuan Tung Rd, Chung Li, 32003, Taiwan
    Sensors (Basel) 10:7772-88. 2010
    ..Finally this paper reviews and compares existing commercial products to provide a comprehensive outlook of current development status and possible emerging technologies...
  8. pmc Tri-axial dynamic acceleration as a proxy for animal energy expenditure; should we be summing values or calculating the vector?
    Lama Qasem
    Biological Sciences, College of Science, Swansea University, Swansea, Wales, United Kingdom
    PLoS ONE 7:e31187. 2012
    Dynamic body acceleration (DBA) has been used as a proxy for energy expenditure in logger-equipped animals, with researchers summing the acceleration (overall dynamic body acceleration--ODBA) from the three orthogonal axes of devices...
  9. pmc The origin of modern frogs (Neobatrachia) was accompanied by acceleration in mitochondrial and nuclear substitution rates
    Iker Irisarri
    Department of Biodiversity and Evolutionary Biology, Museo Nacional de Ciencias Naturales, CSIC, Jose Gutierrez Abascal 2, 28006, Madrid, Spain
    BMC Genomics 13:626. 2012
    ..Although several earlier studies showed that modern frogs (Neobatrachia) experienced an acceleration of mitochondrial gene substitution rates compared to non-neobatrachian relatives, no further characterization ..
  10. ncbi Acceleration patterns of the head and pelvis when walking are associated with risk of falling in community-dwelling older people
    Hylton B Menz
    Prince of Wales Medical Research Institute, University of New South Wales, High Street, Randwick, NSW 2031, Australia
    J Gerontol A Biol Sci Med Sci 58:M446-52. 2003
    ..This study evaluated acceleration patterns of the head and pelvis when walking on a level and an unpredictably irregular surface to determine ..
  11. ncbi Energy cost and metabolic power in elite soccer: a new match analysis approach
    Cristian Osgnach
    School of Sport Sciences, University of Udine, Udine, Italy
    Med Sci Sports Exerc 42:170-8. 2010
    ..We propose a more detailed assessment of soccer players' metabolic demands by video match analysis with the aim of also taking into account accelerations...
  12. pmc Using tri-axial acceleration data to identify behavioral modes of free-ranging animals: general concepts and tools illustrated for griffon vultures
    Ran Nathan
    Movement Ecology Laboratory, Department of Ecology, Evolution and Behavior, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel
    J Exp Biol 215:986-96. 2012
    ..We focus on the use of tri-axial acceleration (ACC) data to identify behavioral modes of GPS-tracked free-ranging wild animals and demonstrate its ..
  13. ncbi Walking speed, cadence and step length are selected to optimize the stability of head and pelvis accelerations
    Mark D Latt
    Department of Geriatric Medicine, Westmead Hospital, Westmead, NSW, Australia
    Exp Brain Res 184:201-9. 2008
    ..b>Acceleration patterns of the head and pelvis were recorded in ten healthy young adults as they walked on a level surface in ..
  14. ncbi Technical reliability assessment of three accelerometer models in a mechanical setup
    Dale W Esliger
    University of Saskatchewan, College of Kinesiology, Saskatoon, Canada
    Med Sci Sports Exerc 38:2173-81. 2006
    ..Secondly, to determine the effects that acceleration and frequency have on these reliability measures.
  15. ncbi Pedestrian Tracking with shoe-mounted inertial sensors
    Eric Foxlin
    InterSense, USA
    IEEE Comput Graph Appl 25:38-46. 2005
  16. ncbi Accelerometers in rehabilitation medicine for older adults
    K M Culhane
    Biomedical Electronics Laboratory, Department of Electronic and Computer Engineering, University of Limerick, Limerick, Ireland
    Age Ageing 34:556-60. 2005
    ..The challenge facing clinicians and biomedical engineers is to further harness this technology making it part of everyday clinical practice...
  17. ncbi Comparison of acceleration signals of simulated and real-world backward falls
    J Klenk
    Robert Bosch Hospital, Department of Clinical Gerontology, Stuttgart, Germany
    Med Eng Phys 33:368-73. 2011
    ..Variation of acceleration and maximum jerk of 5 real-world backward falls of 4 older persons (mean age 68...
  18. ncbi Assessment of spatio-temporal gait parameters from trunk accelerations during human walking
    Wiebren Zijlstra
    Institute of Human Movement Sciences, University of Groningen, PO Box 196, 9700 AD Groningen, The Netherlands
    Gait Posture 18:1-10. 2003
    ..To this purpose, acceleration patterns of the trunk and their relationships with spatio-temporal gait parameters were analysed in healthy ..
  19. pmc Is structured observation a valid technique to measure handwashing behavior? Use of acceleration sensors embedded in soap to assess reactivity to structured observation
    Pavani K Ram
    University at Buffalo, Buffalo, New York 14221, USA
    Am J Trop Med Hyg 83:1070-6. 2010
    ..We assessed reactivity to structured observation in rural Bangladesh by distributing soap containing acceleration sensors and performing structured observation 4 days later. Sensors recorded the number of times soap was moved...
  20. ncbi Ambulatory estimation of foot placement during walking using inertial sensors
    H Martin Schepers
    Institute for Biomedical Technology and Technical Medicine MIRA, University of Twente, AE Enschede, The Netherlands
    J Biomech 43:3138-43. 2010
    ..It is concluded that the ambulatory measurement system was able to reliably estimate foot placement during walking...
  21. ncbi Levels and patterns of objectively assessed physical activity--a comparison between Sweden and the United States
    Maria Hagstromer
    Department of Neurobiology, Karolinska Institutet, Huddinge, Sweden
    Am J Epidemiol 171:1055-64. 2010
    ..These results provide a framework for international comparisons of physical activity levels and patterns, and they represent strong evidence for the importance of investment in objective measurement of physical activity...
  22. ncbi Age-related differences in walking stability
    Hylton B Menz
    Prince of Wales Medical Research Institute, High Street, Randwick, New South Wales 2031, Australia
    Age Ageing 32:137-42. 2003
    ..a large proportion of falls in older people occur when walking; however the mechanisms underlying impaired balance during gait are poorly understood...
  23. ncbi Concussion in professional football: reconstruction of game impacts and injuries
    Elliot J Pellman
    ProHEALTH Care Associates, LLP, Lake Success, New York, USA
    Neurosurgery 53:799-812; discussion 812-4. 2003
    ..Concussion in professional football was studied with respect to impact types and injury biomechanics. A combination of video surveillance and laboratory reconstruction of game impacts was used to evaluate concussion biomechanics...
  24. pmc Frequency and location of head impact exposures in individual collegiate football players
    Joseph J Crisco
    Department of Orthopaedics, The Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, RI 02903, USA
    J Athl Train 45:549-59. 2010
    ..Measuring head impact exposure is a critical step toward understanding the mechanism and prevention of sport-related mild traumatic brain (concussion) injury, as well as the possible effects of repeated subconcussive impacts...
  25. ncbi Ambulatory position and orientation tracking fusing magnetic and inertial sensing
    Daniel Roetenberg
    Biomedical Technology Institute, University of Twente, Enschede 7500 AE, The Netherlands
    IEEE Trans Biomed Eng 54:883-90. 2007
    ..The accuracy was about 5 mm for position and 3 degrees for orientation measurements. Errors were higher during movements with high velocities due to relative movement between source and sensor within one cycle of magnetic actuation...
  26. ncbi Energy expenditure estimated by accelerometry and doubly labeled water: do they agree?
    Nicole Y Leenders
    Sport and Exercise Sciences Section, School of Physical Activity and Educational Services, Ohio State University, Columbus, OH 43210 1228, USA
    Med Sci Sports Exerc 38:2165-72. 2006
    ..The purpose of this study was to compare energy expenditure derived from regression equations determined from accelerometry with energy expenditure obtained from the doubly labeled water method (DLW)...
  27. ncbi Estimation of gait cycle characteristics by trunk accelerometry
    Rolf Moe-Nilssen
    The Balance and Gait Unit, Section of Physiotherapy Science, Institute of Public Health and Primary Health Care, University of Bergen, Ulriksdal 8c, N 5009 Bergen, Norway
    J Biomech 37:121-6. 2004
    ....
  28. pmc Defining accelerometer thresholds for activity intensities in adolescent girls
    Margarita S Treuth
    Center for Human Nutrition, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Med Sci Sports Exerc 36:1259-66. 2004
    ....
  29. ncbi Representation of visual gravitational motion in the human vestibular cortex
    Iole Indovina
    Department of Neuromotor Physiology, Scientific Institute Foundation Santa Lucia, Via Ardeatina 306, 00179 Rome, Italy
    Science 308:416-9. 2005
    ..The acceleration of visual targets was manipulated while brain activity was measured using functional magnetic resonance imaging...
  30. ncbi Direct measurement of human movement by accelerometry
    A Godfrey
    Biomedical Electronics Laboratory, Electronic and Computer Engineering Department, University of Limerick, Limerick, Ireland
    Med Eng Phys 30:1364-86. 2008
    ..Finally the concept of direct measurement by accelerometry is presented with past studies and modern techniques used for data analysis...
  31. ncbi Moving towards acceleration for estimates of activity-specific metabolic rate in free-living animals: the case of the cormorant
    Rory P Wilson
    Institute of Environmental Sustainability, School of the Environment and Society, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, Wales, UK
    J Anim Ecol 75:1081-90. 2006
    ..2. The deployment of data loggers that measure acceleration is emerging as a powerful tool for quantifying the behaviour of free-living animals...
  32. pmc An artificial neural network to estimate physical activity energy expenditure and identify physical activity type from an accelerometer
    John Staudenmayer
    Dept of Mathematics and Statistics, Univ of Massachusetts, Lederle Graduate Research Center, Amherst, MA 01003, USA
    J Appl Physiol (1985) 107:1300-7. 2009
    ..This novel approach of applying ANNs for processing Actigraph accelerometer data is promising and shows that we can successfully estimate activity METs and identify activity type using ANN analytic procedures...
  33. pmc Quantitative relationship between axonal injury and mechanical response in a rodent head impact acceleration model
    Yan Li
    Department of Biomedical Engineering, Wayne State University, Detroit, Michigan 48201, USA
    J Neurotrauma 28:1767-82. 2011
    A modified Marmarou impact acceleration model was developed to study the mechanical responses induced by this model and their correlation to traumatic axonal injury (TAI)...
  34. ncbi Estimating energy expenditure using accelerometers
    Scott E Crouter
    Department of Exercise, Sport, and Leisure Studies, The University of Tennessee, Knoxville, TN, USA
    Eur J Appl Physiol 98:601-12. 2006
    ..05). In conclusion, no single regression equation works well across a wide range of activities for the prediction of EE or time spent in light, moderate, and vigorous physical activity...
  35. ncbi Acceleration patterns of the head and pelvis during gait in older people with Parkinson's disease: a comparison of fallers and nonfallers
    Mark D Latt
    Department of General, Geriatric and Rehabilitation Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    J Gerontol A Biol Sci Med Sci 64:700-6. 2009
    ..Although several studies have evaluated differences in basic gait parameters in people with PD, none have directly evaluated the stability of the upper body during gait...
  36. ncbi Measurement of head impacts in collegiate football players: relationship between head impact biomechanics and acute clinical outcome after concussion
    Kevin M Guskiewicz
    Department of Exercise and Sport Science, Curriculum in Human Movement Science, The University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Neurosurgery 61:1244-52; discussion 1252-3. 2007
    ....
  37. pmc Similar muscles contribute to horizontal and vertical acceleration of center of mass in forward and backward walking: implications for neural control
    Karen Jansen
    Research Center for Movement Control and Neuroplasticity, Department of Biomedical Kinesiology, Katholieke Universiteit Leuven, Leuven, Belgium
    J Neurophysiol 107:3385-96. 2012
    ..In the present study, forward simulations were used to study the effects of muscles on the acceleration of COM in FW and BW...
  38. ncbi Reliability and clinical correlates of 3D-accelerometry based gait analysis outcomes according to age and fall-risk
    Ivan Bautmans
    Gerontology, Vrije Universiteit Brussel, Laarbeeklaan 103, B 1090 Brussels, Belgium
    Gait Posture 33:366-72. 2011
    ..To investigate the reliability of a 3D-accelerometry based gait analysis, and its correlates with clinical status and fall-risk...
  39. ncbi Patterns of objectively measured physical activity in the United States
    Jesse S Metzger
    Departments of Epidemiology, University of North Carolina Chapel Hill, Chapel Hill, NC, USA
    Med Sci Sports Exerc 40:630-8. 2008
    ..We used latent class analysis (LCA) to assess patterns of physical activity among adults, using the 7 d of accelerometer data from the 2003-2004 NHANES...
  40. ncbi The effect of gait speed on lateral balance control during walking in healthy elderly
    Jorunn L Helbostad
    Section of Physiotherapy Science, Faculty of Medicine, University of Bergen, Bergen, Norway
    Gait Posture 18:27-36. 2003
    ..5 years, S.D.=3.2 years), walking at four different self-administered speeds, mediolateral trunk acceleration and step width (SW), but not step-width variability (SWV), were found to have quadratic relations to gait speed...
  41. ncbi Gait assessment in Parkinson's disease: toward an ambulatory system for long-term monitoring
    Arash Salarian
    Laboratory of Movement Analysis and Measurement LMAM, Swiss Federal Institute of Technology EPFL, Lausanne, Switzerland
    IEEE Trans Biomed Eng 51:1434-43. 2004
    ..We concluded that our method provides a simple yet effective way of ambulatory gait analysis in PD patients with results confirming those obtained from much more complex and expensive methods used in gait labs...
  42. ncbi Interstride trunk acceleration variability but not step width variability can differentiate between fit and frail older adults
    Rolf Moe-Nilssen
    The Balance and Gait Unit, Section of Physiotherapy Science, Department of Public Health and Primary Health Care, University of Bergen, Ulriksdal 8c Bergen, N 5009 Norway
    Gait Posture 21:164-70. 2005
    ..In this study we examined the role of step width variability (SWV) and interstride trunk acceleration variability in two groups of fit and frail old people...
  43. pmc Comparing the performance of three generations of ActiGraph accelerometers
    Megan P Rothney
    Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA
    J Appl Physiol (1985) 105:1091-7. 2008
    ..Furthermore, the algorithms for energy expenditure predictions developed using older 7164 monitors may need to be modified for the GT1M...
  44. pmc Brain injury prediction: assessing the combined probability of concussion using linear and rotational head acceleration
    Steven Rowson
    Center for Injury Biomechanics, Virginia Tech Wake Forest, 440 ICTAS Building, Stanger St, Blacksburg, VA 24061, USA
    Ann Biomed Eng 41:873-82. 2013
    ..In the HITS dataset, the combined probability of concussion and linear acceleration were significantly better predictors of concussion than rotational acceleration alone, but not different from ..
  45. ncbi Inertial sensor-based knee flexion/extension angle estimation
    Glen Cooper
    Centre for Rehabilitation and Human Performance Research, University of Salford, UK
    J Biomech 42:2678-85. 2009
    A new method for estimating knee joint flexion/extension angles from segment acceleration and angular velocity data is described...
  46. ncbi Discrimination of walking patterns using wavelet-based fractal analysis
    Masaki Sekine
    Department of Gerontechnology, National Institute for Longevity Sciences, Ohbu, Aichi 474 8522, Japan
    IEEE Trans Neural Syst Rehabil Eng 10:188-96. 2002
    In this paper, we attempted to classify the acceleration signals for walking along a corridor and on stairs by using the wavelet-based fractal analysis method...
  47. pmc Head impacts during high school football: a biomechanical assessment
    Steven P Broglio
    Department of Kinesiology and Community Health, University of Illinois at Urbana Champaign, Champaign, IL 61801, USA
    J Athl Train 44:342-9. 2009
    ..Little is known about the impact biomechanics sustained by players during interscholastic football...
  48. ncbi Multiple reference frames for motion in the primate cerebellum
    Aasef G Shaikh
    Department of Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 24:4491-7. 2004
    ..This differential representation of motion-related information implies potential differences in the functional roles of these areas...
  49. ncbi Validity and reliability of GPS for measuring instantaneous velocity during acceleration, deceleration, and constant motion
    Matthew C Varley
    Institute of Sport, Exercise and Active Living, Victoria University, Melbourne, Victoria, Australia
    J Sports Sci 30:121-7. 2012
    ..and reliability of 5 and 10 Hz global positioning systems (GPS) for measuring instantaneous velocity during acceleration, deceleration, and constant velocity while straight-line running...
  50. ncbi Increased high-intensity activity in elite Australian football finals matches
    Robert J Aughey
    Institute of Sport, Exercise and Active Living, Victoria University, Melbourne, Australia
    Int J Sports Physiol Perform 6:367-79. 2011
    ..Players aim to be in peak physical condition for finals, with anecdotal evidence of increased speed and pressure of these games...
  51. ncbi Quaternion-based extended Kalman filter for determining orientation by inertial and magnetic sensing
    Angelo M Sabatini
    ARTS Lab, Scuola Superiore Sant Anna, Piazza Martiri della Libertà, Pisa 56127, Italy
    IEEE Trans Biomed Eng 53:1346-56. 2006
    ....
  52. ncbi Evaluation of a fall detector based on accelerometers: a pilot study
    U Lindemann
    Robert Bosch Krankenhaus, Department of Geriatric Rehabilitation, Stuttgart, Germany
    Med Biol Eng Comput 43:548-51. 2005
    ..The sensitivity of the fall detection was assessed by investigation into the acceleration patterns of the head of a young volunteer during intentional falls...
  53. ncbi Reciprocal angular acceleration of the ankle and hip joints during quiet standing in humans
    Y Aramaki
    Educational Physiology Laboratory, Graduate School of Education, The University of Tokyo, Japan
    Exp Brain Res 136:463-73. 2001
    ..Further, measurement error was not predominant, even among the angular acceleration data, which were obtained by taking the second derivative of the angular displacement...
  54. ncbi Perception of tilt (somatogravic illusion) in response to sustained linear acceleration during space flight
    G Clement
    Centre de Recherche Cerveau et Cognition, CNRS UPS, Toulouse, France
    Exp Brain Res 138:410-8. 2001
    ..the Gy (interaural) axis, induced illusions of roll-tilt of 20 degrees and 34 degrees for gravito-inertial acceleration (GIA) vector tilts of 27 degrees and 45 degrees , respectively. Pre-flight 0...
  55. ncbi A comparison of questionnaire, accelerometer, and pedometer: measures in older people
    Tess J Harris
    Division of Community Health Sciences, St George s, University of London, London, UK
    Med Sci Sports Exerc 41:1392-402. 2009
    ....
  56. ncbi The landing-take-off asymmetry in human running
    G A Cavagna
    Istituto di Fisiologia Umana, Universita degli Studi di Milano, Via Mangiagalli, 32, 20133 Milan, Italy
    J Exp Biol 209:4051-60. 2006
    ..positive work phase, due to the muscular push continuing to accelerate the body forwards after the end of the acceleration upwards...
  57. ncbi Reliability of segmental accelerations measured using a new wireless gait analysis system
    Justin J Kavanagh
    School of Physiotherapy and Exercise Science, Griffith University, PMB 50 Gold Coast Mail Centre 9726, Gold Coast, Queensland, Australia
    J Biomech 39:2863-72. 2006
    ..Furthermore, differences in acceleration waveform repeatability associated with the reapplication of accelerometers were small in relation to normal ..
  58. ncbi Improving physical activity assessment in prepubertal children with high-frequency accelerometry monitoring: a methodological issue
    Georges Baquet
    Laboratory of Human Movement Studies EA 3608, Faculty of Sport Sciences and Physical Education, University of Lille 2, 9 rue de l Université 59790, Ronchin, France
    Prev Med 44:143-7. 2007
    ..The aim of this study was to examine the duration of physical activity (PA) bouts in prepubertal children with high-frequency accelerometry monitoring...
  59. ncbi Precision of measurements of physical workload during standardised manual handling. Part II: Inclinometry of head, upper back, neck and upper arms
    G A Hansson
    Department of Occupational and Environmental Medicine, University Hospital, SE 221 85 Lund, Sweden
    J Electromyogr Kinesiol 16:125-36. 2006
    ..The contribution of the measurement procedure per se to the between-days variability, i.e., the imprecision of the method, was small: less than 2 degrees for angles and 3% for angular velocity...
  60. ncbi Vestibular signals in primate thalamus: properties and origins
    Hui Meng
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 27:13590-602. 2007
    ..01-4 Hz. During translation, neurons encoded combinations of linear acceleration and velocity...
  61. ncbi Sensitivity and specificity of fall detection in people aged 40 years and over
    Maarit Kangas
    Department of Medical Technology, Institute of Biomedicine, University of Oulu, Oulu, Finland
    Gait Posture 29:571-4. 2009
    ..5% and a specificity of 100%. This suggests that the present concept provides an effective method for automatic fall detection...
  62. pmc Estimation of daily energy expenditure in pregnant and non-pregnant women using a wrist-worn tri-axial accelerometer
    Vincent T van Hees
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    PLoS ONE 6:e22922. 2011
    ....
  63. ncbi Acceleration-based gait test for healthy subjects: reliability and reference data
    R Senden
    Atrium Medical Center, Department of Orthopaedics and Traumatology, Heerlen, Henri Dunantstraat 5, Heerlen, P O Box 4446, 6401 CX Heerlen, The Netherlands
    Gait Posture 30:192-6. 2009
    ..The aim of this study was to present an acceleration-based reference database for healthy gait...
  64. pmc How soccer players head the ball: a test of Optic Acceleration Cancellation theory with virtual reality
    Peter McLeod
    Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
    Vision Res 48:1479-87. 2008
    ..claim that players intercepting balls use servo control strategies and are consistent with the particular claim of Optic Acceleration Cancellation theory that the servo strategy is to allow alpha to increase at a steadily decreasing rate.
  65. pmc Vestibular heading discrimination and sensitivity to linear acceleration in head and world coordinates
    Paul R MacNeilage
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 30:9084-94. 2010
    ..e., heading. The vestibular cue to heading is the direction of inertial acceleration that accompanies transient linear movements. This cue is transduced by the otolith organs...
  66. ncbi The generalized optic acceleration cancellation theory of catching
    Peter McLeod
    Department of Experimental Psychology, Oxford University, Oxford, England
    J Exp Psychol Hum Percept Perform 32:139-48. 2006
    The generalized optic acceleration cancellation (GOAC) theory of catching proposes that the path of a fielder running to catch a ball is determined by the attempt to satisfy 2 independent constraints...
  67. ncbi Maturation of otolith-related brainstem neurons in the detection of vertical linear acceleration in rats
    Suk King Lai
    Department of Physiology, Faculty of Medicine, The University of Hong Kong, Sassoon Road, Hong Kong
    Eur J Neurosci 23:2431-46. 2006
    ..Conscious rats were subjected to sinusoidal linear acceleration along the vertical plane...
  68. pmc A feedback model explains the differential scaling of human postural responses to perturbation acceleration and velocity
    Torrence D J Welch
    The Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332 0535, USA
    J Neurophysiol 101:3294-309. 2009
    ..was experimentally modulated using 34 different anterior-posterior support-surface translations of varying peak acceleration and velocity but the same total displacement...
  69. ncbi Gait posture estimation using wearable acceleration and gyro sensors
    Ryo Takeda
    Division of Human Mechanical Systems and Design, Graduate School of Engineering, Hokkaido University, N13 W8, Kita ku, Sapporo 060 8628, Japan
    J Biomech 42:2486-94. 2009
    A method for gait analysis using wearable acceleration sensors and gyro sensors is proposed in this work. The volunteers wore sensor units that included a tri-axis acceleration sensor and three single axis gyro sensors...
  70. ncbi Wearable assistant for Parkinson's disease patients with the freezing of gait symptom
    Marc Bächlin
    Wearable Computing Laboratory, Swiss Federal Institute of Technology Zurich, Zurich CH 8092, Switzerland
    IEEE Trans Inf Technol Biomed 14:436-46. 2010
    ..This wearable system uses on-body acceleration sensors to measure the patients' movements...
  71. ncbi Reliability and validity of bilateral thigh and foot accelerometry measures of walking in healthy and hemiparetic subjects
    Kaveh Saremi
    Neurologic Rehabilitation and Research Program, Department of Neurology, Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
    Neurorehabil Neural Repair 20:297-305. 2006
    ..A new integrated system of 5 accelerometers was tested for reliability and compared to a footswitch system to determine if the accelerometers offered a practical option for the acquisition of spatiotemporal gait parameters...
  72. ncbi Quaternion-based strap-down integration method for applications of inertial sensing to gait analysis
    A M Sabatini
    Scuola Superiore Sant Anna, Pisa, Italy
    Med Biol Eng Comput 43:94-101. 2005
    ..8 degrees and RMSE(d) = 30.0 cm for an integration interval of two gait cycles (an improvement of 11 degrees and 262 cm)...
  73. ncbi Reproducibility of a triaxial seismic accelerometer (DynaPort)
    Vincent T van Hees
    Faculty of Human Movement Sciences, VU University, Amsterdam, The Netherlands
    Med Sci Sports Exerc 41:810-7. 2009
    ..To examine the reproducibility of a triaxial seismic accelerometer under controlled conditions and real-life conditions...
  74. ncbi Using objective physical activity measures with youth: how many days of monitoring are needed?
    S G Trost
    Department of Exercise, School of Public Health, University of South Carolina, Columbia 29208, USA
    Med Sci Sports Exerc 32:426-31. 2000
    ..The purpose of this study was to establish the minimal number of days of monitoring required for accelerometers to assess usual physical activity in children...
  75. ncbi Distance to achieve steady state walking speed in frail elderly persons
    U Lindemann
    Robert Bosch Hospital, Department of Geriatric Rehabilitation, 70376, Stuttgart, Germany
    Gait Posture 27:91-6. 2008
    ..On average, participants reached a walking speed of 0.66 m/s after an acceleration phase of 1.43 m (89% after 2.47 m)...
  76. ncbi Estimation and visualization of sagittal kinematics of lower limbs orientation using body-fixed sensors
    Hooman Dejnabadi
    Ecole Polytechnique Federale de Lausanne EPFL, Laboratory of Movement Analysis and Measurement, 1015 Lausanne, Switzerland
    IEEE Trans Biomed Eng 53:1385-93. 2006
    ..Finally, a gait analysis tool was designed to visualize the motion data as synthetic skeletons performing the same actions as the subjects...
  77. ncbi Analysis of stroke patient walking dynamics using a tri-axial accelerometer
    Chihiro Mizuike
    School of Rehabilitation Sciences, Seirei Christopher University, 3453 Mikatabara cho, Kita ku, Hamamatsu, Shizuoka 433 8558, Japan
    Gait Posture 30:60-4. 2009
    The purpose of this study was to describe the characteristics of stroke patient gait using the acceleration signals which were obtained during walking...
  78. ncbi Evaluation of waist-mounted tri-axial accelerometer based fall-detection algorithms during scripted and continuous unscripted activities
    A K Bourke
    Biomedical Electronics Laboratory, Department of Electronic and Computer Engineering, Faculty of Science and Engineering, University of Limerick, Limerick, Ireland
    J Biomech 43:3051-7. 2010
    ..This algorithm is the most suitable method of fall-detection, when tested using continuous unscripted activities performed by elderly healthy volunteers, which is the target environment for a fall-detection device...
  79. pmc Head impact severity measures for evaluating mild traumatic brain injury risk exposure
    Richard M Greenwald
    Simbex, Lebanon, New Hampshire, USA
    Neurosurgery 62:789-98; discussion 798. 2008
    The aims of this study were to quantify the sensitivity of various biomechanical measures (linear acceleration, rotational acceleration, impact duration, and impact location) of head impact to the clinical diagnosis of concussion in ..
  80. ncbi Controlling human upright posture: velocity information is more accurate than position or acceleration
    John Jeka
    Program in Neuroscience and Cognitive Science, University of Maryland, College Park, MD 20742 2611, USA
    J Neurophysiol 92:2368-79. 2004
    ..g., velocity, acceleration) information for estimation of body dynamics...
  81. ncbi Comparison of the performance of the activPAL Professional physical activity logger to a discrete accelerometer-based activity monitor
    A Godfrey
    Biomedical Electronics Laboratory, Department of Electronic and Computer Engineering, University of Limerick, Limerick, Ireland
    Med Eng Phys 29:930-4. 2007
    ....
  82. ncbi Clinimetric review of motion sensors in children and adolescents
    Sanne I de Vries
    TNO Quality of Life, Department of Physical Activity and Health, P O Box 2215, 2301 CE, Leiden, The Netherlands
    J Clin Epidemiol 59:670-80. 2006
    ..To review the clinimetric quality of motion sensors used to assess physical activity in healthy children and adolescents (2-18 years)...
  83. ncbi How active are people with stroke?: use of accelerometers to assess physical activity
    Debbie Rand
    PT OT, Department of Physical Therapy, University of British Columbia, T325 2211 Westbrook Mall, Vancouver, BC, V6T 2B5, Canada
    Stroke 40:163-8. 2009
    ..The secondary aims were to measure the amount of physical activity with accelerometers that people with stroke undertake in the community and its relationship with walking capacity (6-minute walk test distance)...
  84. ncbi Physical activity levels and patterns of 9- and 15-yr-old European children
    Chris J Riddoch
    Department of Exercise and Health Sciences, University of Bristol, Bristol, UK
    Med Sci Sports Exerc 36:86-92. 2004
    ..Very limited physical activity data exist that have been collected from representative samples of children and even fewer data collected where physical activity has been measured using objective methods...
  85. ncbi Ambulatory monitoring of physical activities in patients with Parkinson's disease
    Arash Salarian
    Laboratory of Movement Analysis and Measurement LMAM, Ecole Polytechnique Federale de Lausanne EPFL, STI LMAM, ELG 239, Lausanne Vaud 1024, Switzerland
    IEEE Trans Biomed Eng 54:2296-9. 2007
    ..We concluded that our method provides a simple, accurate, and effective means to objectively quantify physical activities in both normal and PD patients and may prove useful to assess the level of motor functions in the latter...
  86. ncbi Hierarchy of individual calibration levels for heart rate and accelerometry to measure physical activity
    Søren Brage
    MRC Epidemiology Unit, Cambridge CB1 9NL, UK
    J Appl Physiol (1985) 103:682-92. 2007
    ..69 (0.10) m, 70 (14) kg]. Acceleration (along the longitudinal axis of the trunk) and HR were measured simultaneously...
  87. ncbi Calibration of accelerometer output for children
    Patty Freedson
    Department of Exercise Science, University of Massachusetts, Amherst, MA 01003, USA
    Med Sci Sports Exerc 37:S523-30. 2005
    ..Alternative data processing using the raw acceleration signal is recommended as a possible alternative approach where the actual acceleration pattern is used to ..
  88. pmc Imputation of missing data when measuring physical activity by accelerometry
    Diane J Catellier
    Department of Biostatistics, University of North Carolina, Chapel Hill, NC 27514 4145, USA
    Med Sci Sports Exerc 37:S555-62. 2005
    ..The fact that counts are not being recorded during periods in which the monitor is not worn means that many common estimators of daily physical activity are biased downward...
  89. ncbi Calibration of an accelerometer during free-living activities in children
    Calum Mattocks
    Department of Social Medicine, University of Bristol, Bristol, UK
    Int J Pediatr Obes 2:218-26. 2007
    ..The aims of this study were to develop an equation to predict energy expenditure and to derive cut-points for moderate and vigorous physical activity intensity from the Actigraph accelerometer output in children aged 12 years...
  90. pmc Fast and efficient fully 3D PET image reconstruction using sparse system matrix factorization with GPU acceleration
    Jian Zhou
    Department of Biomedical Engineering, University of California, Davis, CA 95616, USA
    Phys Med Biol 56:6739-57. 2011
    ..we present a method to address this problem using sparse matrix factorization and graphics processor unit (GPU) acceleration. We factor the accurate system matrix into three highly sparse matrices: a sinogram blurring matrix, a ..
  91. ncbi Specificity of acceleration, maximum speed, and agility in professional soccer players
    Thomas Little
    Sport, Health and Exercise, Staffordshire University, Stoke on Trent, Staffordshire, UK
    J Strength Cond Res 19:76-8. 2005
    ..actions are known to impact soccer performance and can be categorized into actions requiring maximal speed, acceleration, or agility...
  92. ncbi An instrumented timed up and go: the added value of an accelerometer for identifying fall risk in idiopathic fallers
    A Weiss
    Laboratory for Gait and Neurodynamics, Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Physiol Meas 32:2003-18. 2011
    ..3 ± 9.1 years) performed the TUG while wearing a 3D-accelerometer on the lower back. Acceleration-derived parameters included Sit-to-Stand and Stand-to-Sit times, amplitude range (Range), and slopes (Jerk)...
  93. ncbi Activity-monitor accuracy in measuring step number and cadence in community-dwelling older adults
    P Margaret Grant
    School of Health and Social Care, Glasgow Caledonian University, Glasgow, UK
    J Aging Phys Act 16:201-14. 2008
    ..The activPAL monitor accurately recorded step number and cadence. Combined with its ability to identify primary postures, the activPAL might be a useful and versatile device for measuring activity in older adults...
  94. ncbi The need for speed: testing acceleration for estimating animal travel rates in terrestrial dead-reckoning systems
    Owen R Bidder
    Biological Sciences, College of Science, Swansea University, Singleton Park, Swansea SA2 8PP, UK
    Zoology (Jena) 115:58-64. 2012
    ..In the present study we evaluate the use of accelerometers and a metric known as overall dynamic body acceleration (ODBA) as a proxy for the measurement of speed for use in dead-reckoning...
  95. ncbi Analysis of real-time head accelerations in collegiate football players
    Stefan M Duma
    Virginia Tech Wake Forest Center for Injury Biomechanics, Blacksburg, VA 24061, USA
    Clin J Sport Med 15:3-8. 2005
    ..To measure and analyze head accelerations during American collegiate football practices and games...
  96. ncbi Developmental maturation of ionotropic glutamate receptor subunits in rat vestibular nuclear neurons responsive to vertical linear acceleration
    Suk King Lai
    Department of Physiology, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong, China
    Eur J Neurosci 28:2157-72. 2008
    ..of ionotropic glutamate receptors in vestibular nuclear neurons that were activated by sinusoidal linear acceleration along the vertical plane...
  97. ncbi Field evaluation of energy expenditure in women using Tritrac accelerometers
    Kristin L Campbell
    School of Human Kinetics, University of British Columbia, Vancouver, BC, Canada
    Med Sci Sports Exerc 34:1667-74. 2002
    ..To investigate the use of Tritrac accelerometers to measure energy expenditure (EE) of various activities for women in the field setting, as compared with portable indirect calorimetry...
  98. ncbi Reducing impact loading during running with the use of real-time visual feedback
    Harrison Philip Crowell
    US Army Research Laboratory, RDRL HRS B, Aberdeen Proving Ground, MD 21005 5425, USA
    J Orthop Sports Phys Ther 40:206-13. 2010
    ..Single-subject with repeated measures...
  99. ncbi Performance and scalability of Fourier domain optical coherence tomography acceleration using graphics processing units
    Jian Li
    School of Engineering Sciences, Simon Fraser University, V5A 1S6 Burnaby, BC, Canada
    Appl Opt 50:1832-8. 2011
    ..Finally, we discuss how the performance trends of GPU-based accelerators compare to the expected future requirements of FD-OCT data rates...
  100. ncbi Nonexercise movement in elderly compared with young people
    Ann M Harris
    Endocrine Research Unit, Mayo Clinic, Rochester, MN 55905, USA
    Am J Physiol Endocrinol Metab 292:E1207-12. 2007
    ..Total nonexercise movement (acceleration arbitrary units), standing time, and standing acceleration were significantly lower in the elderly subjects; ..
  101. pmc Identifying sedentary time using automated estimates of accelerometer wear time
    Elisabeth A H Winkler
    School of Population Health, The University of Queensland, Brisbane, Australia
    Br J Sports Med 46:436-42. 2012
    ..Direct effects on sedentary time (<100 cpm) and indirect effects on moderate-to-vigorous physical activity (MVPA, ≥1952 cpm) time were examined...

Research Grants77

  1. METABOLIC SYNDROME AND PERIODONTITIS IN POSTMENOPAUSAL WOMEN
    Michael J LaMonte; Fiscal Year: 2013
    ..S. adults 55 years and older. Metsyn is a putative factor for modified host immune response and acceleration of periodontitis...
  2. Immunomodulatory and regenerative effects of mesenchymal stem cells on allografts
    Norma S Kenyon; Fiscal Year: 2013
    ..This team will provide a powerful mechanism for data mining and analysis, thereby resulting in acceleration of the discovery process, as compared to the outcome of a single PI working to put together genomic and ..
  3. Dietary Lipids and Silica-Accelerated Autoimmunity
    James J Pestka; Fiscal Year: 2013
    ..it will be an initial step in the path to predicting how n-3 PUFA consumption might prevent or ameliorate acceleration of autoimmunity by silica and other toxicants...
  4. Modifiers of Cyst Progression in Polycystic Kidney Disease
    Phillip Darwin Bell; Fiscal Year: 2013
    ..That the presence of reduced renal mass or elevated blood glucose levels result in the initiation and acceleration of cystogenesis in mouse models of PKD...
  5. UNDERSTANDING VIBRATION INJURY
    Danny A Riley; Fiscal Year: 2013
    ..The risk factors of vibration frequency (Hz), acceleration (m/s2 r.m.s.), amplitude (mm) and duration (vibration/day and days of vibration) that lead to HAVS are assessed...
  6. Exploratory Studies on the Anti-Breast Cancer Function of Bamboo Extract
    Jun Panee; Fiscal Year: 2010
    ..ii) Enhancement of estrogen metabolism through up-regulation of SULT activity in the liver. (iii) Acceleration of mammary gland differentiation through its potential phytoestrogenic activity...
  7. TSAD AS AN EPOR/JAK2 ADAPTOR AND ERYTHROPOIETIC REGULATOR
    DONALD JOSEPH MCCRANN; Fiscal Year: 2010
    ..Adversely, EPO treatment is also associated with the acceleration of cancer progression and with increased thrombolytic events...
  8. Interaction of fetal growth and bisphenol A in obesity
    Frederick S vom Saal; Fiscal Year: 2013
    ..In addition, a low maternal oral dose of BPA is predicted to exacerbate obesity in IUGR offspring due to acceleration of postnatal growth...
  9. OLFACTORY RECEPTOR COPY NUMBER ASSOCIATION WITH AGE AT ONSET OF ALZHEIMER DISEASE
    Kinga Szigeti; Fiscal Year: 2013
    ..The short-term goals are to i) learn analyses techniques of large datasets in the era of technical acceleration which allows the generation of large numbers of genetic data points (array experiments), ii) further the ..
  10. Selective Insulin Resistance- Diabetic Cardiovascular Diseases
    George L King; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Cardiovascular pathologies in diabetic patients are caused by the acceleration of atherosclerosis...
  11. Estrogen, Aging and Vascular Inflammation
    Anne A Knowlton; Fiscal Year: 2013
    ..In females, loss of estrogen compounds these changes. Post-menopausal women have an abrupt acceleration of atherosclerosis...
  12. Advanced Magnetization Transfer Imaging in Multiple Sclerosis Disease
    Alexey Samsonov; Fiscal Year: 2012
    ..The variable sampling density with these trajectories allows acceleration through undersampling, but more importantly provides a foundation for accelerating qMTI through model-based ..
  13. USHERIN: STRUCTURAL AND FUNCTIONAL ANALYSIS
    DOMINIC E COSGROVE; Fiscal Year: 2012
    ..This work will help align the field and promote an acceleration of work aimed at understanding the specific disease mechanism, which is an essential first step towards the ..
  14. Novel CNS Target for Sleep-Wake and Psychiatric Disorders
    SCOTT MCNEAR THACHER; Fiscal Year: 2010
    ..point to clinical utility, such as constant entrainment with respect to light for a sleep phase disorder, or acceleration of entrainment following a 6 h shift in the light-dark cycle resembling jet lag...
  15. REACTIVE OXYGEN SPECIES: STRESS AND DAMAGE IN OLD MUSCLE
    Susan V Brooks; Fiscal Year: 2012
    ..to increased oxidative stress and damage in motor neurons, skeletal muscle fibers and mitochondria that cause acceleration in the development of age-related muscle atrophy and weakness...
  16. Somatosensory feedback controlling a neuroprosthesis
    Douglas J Weber; Fiscal Year: 2010
    ..decerebate cat preparation, the following state variables for the hindlimb will be studied: position, velocity, acceleration, endpoint force (e.g. ground reaction force during stance), and stance phase joint-torque...
  17. A Mouse Model for Emotional Disorder Caused by Mild Traumatic Brain Injury
    ANTON J REINER; Fiscal Year: 2013
    ..Mild TBI involves closed-head injury from a primary blast shock wave, or head acceleration - deceleration during a collision...
  18. Body Composition and Energy Utilization in Spinal Muscular Atrophy
    Douglas Michael Sproule; Fiscal Year: 2012
    ..The development of biomarkers of disease progression (and treatment effect) is critical in the acceleration of early stage clinical trials...
  19. ADULT STEM CELL SUPPRESSION DUE TO ALCOHOL INDUCED MICROENVIRONMENT ALTERATIONS
    Mandi J Lopez; Fiscal Year: 2010
    ..pleuripotential capacity of ASCs;(B) That chronic alcohol exposure in the recipient inhibits or prevents the acceleration of spinal fusion by application of normal ASCs in a suitable biomaterial carrier;and (C) That ASCs harvested ..
  20. Stat5b in Lymphomagenesis: Mechanistic and Therapeutic Implications
    John A Kelly; Fiscal Year: 2012
    ..Indeed, acceleration of Stat5b transgene-mediated lymphoma occurred on TCR[unreadable]-/- and pre-TCR[unreadable]-/- backgrounds2...
  21. Malaria treatment outcomes and pharmacokinetics in HIV-infected pregnant women
    MYAING MYAING NYUNT; Fiscal Year: 2010
    ..pregnancy- and HIV-related immune suppression and suboptimal pharmacokinetics secondary to pregnancy-induced acceleration in drug disposition may hamper the efficacy of artemether-lumefantrine...
  22. The Role of Toll-Like Receptor-3 in T1D and Efficacy of a Novel Therapeutic
    Kelly McCall; Fiscal Year: 2010
    ..Thus, the specific aim of this proposal is to evaluate the contribution(s) of TLR3 signaling to CBV-4-induced acceleration of T1D in NOD mice and the mechanism by which C10 attenuates CBV-4 acceleration of T1D in the NOD mouse by ..
  23. Effects of maternal cortisol on fetal and neonatal growth and metabolism
    Maureen Keller-Wood; Fiscal Year: 2013
    ..and the normal increases in maternal cardiac output and uteroplacental blood flow that are essential for acceleration of fetal growth in the late gestation, and secondarily, by reducing maternal food intake and maternal and fetal ..
  24. Mechanism of Thin Filament Regulation of Cardiac Actomyosin Hydrolysis
    Howard White; Fiscal Year: 2009
    ..Multi-mixing stopped-flow will be used to measure the dependence of the acceleration of product dissociation (Pi and ADP) from cardiac myosin-ADP-Pi by native cardiac thin filaments upon calcium ..
  25. Prev. of Cardiovas. Complications of Pediatric SLE: Artherosclerosis Prev in Pedi
    Laura E Schanberg; Fiscal Year: 2009
    ..b>Acceleration of atherogenesis in SLE most likely reflects SLE-associated vascular immune and inflammatory changes...
  26. Age-Dependent Mechanisms in Thoracic Aortic Aneurysms
    John S Ikonomidis; Fiscal Year: 2013
    ..There are presently no available indices to determine which patients may be at greater risk for acceleration of TAA development, warranting more immediate treatment...
  27. FACTOR VA INTERACTIONS REGULATING PROTHROMBIN ACTIVATION
    Paul E Bock; Fiscal Year: 2010
    ..by exosite-mediated competitive binding of factor Xa and APC to factor Va for cleavage at Arg506, and specific acceleration of cleavage at Arg306 by protein S...
  28. Dopamine Exacerbates NeuroAIDS by Activation of Macrophage Dopaminergic System
    PETER JESSE GASKILL; Fiscal Year: 2013
    ..The mechanism(s) leading to the acceleration HAND remain unclear;however, both cocaine and methamphetamine act by increasing in extracellular levels of the ..
  29. Genetic and Inflammatory Factors in Anemia in the Elderly
    Nancy Berliner; Fiscal Year: 2010
    ..a frail state similar to that seen in the elderly with a more frequent and earlier anemia that reflects an acceleration of the inflammatory process associated with aging. Our specific aims are: 1...
  30. Efficacy &safety of baclofen to reduce alcohol use in veterans with HCV
    Peter Hauser; Fiscal Year: 2013
    ..Such medication could both slow the acceleration of liver disease caused by alcohol use and increase the likelihood of receiving antiviral therapy...
  31. The Effects of Frailty on Chronic Kidney Disease
    Cynthia Delgado; Fiscal Year: 2013
    ..between frailty and CKD actually bidirectional? Third, is the mechanism central to the association driven by an acceleration of chronic inflammation? To date, most work has focused on the hypothesis that CKD leads to frailty, but it is ..
  32. Genetic Analysis of Chordoma
    Michael J Kelley; Fiscal Year: 2012
    ..Recently, there has been acceleration in application of molecular predictors to guide clinical decision making with an ultimate goal of ..
  33. Isothiocyanate-Mediated Breast Cancer Prevention
    Louise R Howe; Fiscal Year: 2013
    ..induced by carcinogen treatment, most likely as a consequence of Phase II enzyme induction and resultant acceleration of carcinogen deactivation...
  34. Mechanisms of Prostacyclin-Mediated Lung Endothelial Barrier Protection
    Konstantin Birukov; Fiscal Year: 2013
    ..We hypothesize that signaling by Rap1 GTPase plays a dual role in PC-induced acceleration of ALI resolution via promotion of EC barrier repair and suppression of inflammatory endothelial activation...
  35. FUNCTIONAL MRI DATA AQUISITION AND ANALYSIS
    James J Pekar; Fiscal Year: 2011
    ..0 Tesla. We will optimize fMRI acquisitions at 7.0 T with respect to parallel imaging acceleration factor, shimming, TE and TR choice, and slice number, depending on the individual needs for our neuroscience ..
  36. The Role of Innate Immunity in Systemic and Cutaneous Lupus
    JOANNE MICHELLE KAHLENBERG; Fiscal Year: 2013
    ..Development of a persistent lupus-like rash, inflammatory infiltrate composition and acceleration of systemic disease development will be monitored.
  37. Identifying enhancers with human-specific developmental functions
    James P Noonan; Fiscal Year: 2013
    ..Here we will build on these previous studies to generate more sophisticated maps of human-specific sequence acceleration in noncoding elements, including transcription factor binding site data and ChIP-seq data generated by genome-..
  38. Molecular basis of homocysteine-glutamate receptor mediated neuronal cell death
    Ranjana Poddar; Fiscal Year: 2012
    ..the blood-brain barrier and increased levels of homocysteine in brain is associated with aggravation and acceleration of neuronal damage in ischemic stroke, Alzheimer's and Parkinson's diseases...
  39. The role of Myocardial Substrate Metabolism in Heart Failure
    MOGAMMAD FAADIEL ESSOP; Fiscal Year: 2013
    ..There are two Specific Aims: Aim 1: Evaluate the role of HBP in the acceleration of heart failure with a high sugar diet...
  40. Regulation and function of mammalian HSF4 in vivo
    Nahid F Mivechi; Fiscal Year: 2012
    ..factor Hsf4 exhibits properties of a tumor suppressor gene and its functional loss is associated with acceleration of tumorigenesis demonstrated in mouse models...
  41. Defining molecular biomarkers for CDK4/6-based cancer therapy by RNA sequencing
    CHRISTOPHER EDWARD MASON; Fiscal Year: 2013
    ..Together with overexpression of cyclin-dependent kinase (CDK)4, this leads to cell cycle acceleration and unrestrained proliferation of tumor cells that underlies disease progression...
  42. Tpl2 in Intestinal Tumorigenesis
    Philip N Tsichlis; Fiscal Year: 2013
    ..Tpl2-/-/ Apcmin/+ mice exhibited a 5-fold increase in the number of intestinal polyps and a significant acceleration in tumorigenesis relative to their Tpl2+/+/Apcmin/+ littermates...
  43. CORAL: Economics and QOL Core Laboratory
    David J Cohen; Fiscal Year: 2013
    ..ischemia leads to neuroendocdne activation, hypertension, and renal insufficiency potentially resulting in acceleration of therosclerosis, further renal dysfunction, myocardial infarction, stroke and death...
  44. Sensor Network for Monitoring Real-world Arm Activity of Rehabilitation Patients
    Gitendra Uswatte; Fiscal Year: 2010
    ..An acceleration sensor will be used to trigger the RFID tag when a tagged object is moved...
  45. The Role of RGS Proteins in the Regulation of Taste Transduction
    Staci P Cohen; Fiscal Year: 2013
    ..RGS proteins towards taste-specific G[unreadable] subunits in biochemical assays of binding and GTP hydrolysis acceleration. Aim 3 is to determine the effects of RGS proteins on tastant signaling outcomes in an integrated cellular ..
  46. Innate Immunity and Pathogen mediated Acceleration in Vascular Inflammation
    Shuang Chen; Fiscal Year: 2013
    ..inflammasome pathway as well a NOD/Rip2 signaling pathway (by modulating the IL-17 pathway) in CP-induced acceleration of atherosclerosis and vascular inflammation...
  47. Innate Immune Bacterial Recognition and Osteoclastogenesis
    Caroline A Genco; Fiscal Year: 2010
    ..In other inflammatory bone diseases these cells have been reported to contribute to the acceleration of bone resorption by the production of proinflammatory cytokines including tumor necrosis factor (TNF)-, ..
  48. Microvesicle production after trauma &its Clinical Impact on Venothromboembolism
    Myung S Park; Fiscal Year: 2013
    ..from traumatic injuries, the clotting mechanism in the blood is accelerated, but the mechanism involved in this acceleration is not clearly understood...
  49. SGK1 Signaling Pathways in Vascular Remodeling
    Sharon Francis; Fiscal Year: 2013
    ..This correlated with an acceleration of cell cycle progression owing to an increase in G1 to S transition...
  50. Antidepressant Therapy for Functional Dyspepsia
    YURI ANN SAITO LOFTUS; Fiscal Year: 2011
    ..2) Acceleration of solid gastric emptying, reduction of postprandial satiation and enhanced gastric volume change with a meal ..
  51. Lipid Regulation of Thrombin Generation
    Barry R Lentz; Fiscal Year: 2012
    ..to a widely help paradigm, our work shows that PS molecules, not a membrane surface, trigger this remarkable acceleration. This has eluded researchers because PS is located in membranes where protein structure and interactions are ..
  52. Bioethics Research Infrastructure Initiative
    CLAUDIA ROSE BAQUET; Fiscal Year: 2010
    ..Through this approach and the aims, we will support the acceleration of the national research enterprise across the continuum...
  53. RECOVERY OF PHOTOTRANSDUCTION
    Ching Kang Jason Chen; Fiscal Year: 2013
    ..Aim-1 will investigate mechanism and function of rhodopsin kinase mediated acceleration of phototransduction recovery to determine whether a higher level of rhodopsin kinase in cone help to ..
  54. Tooth Root Formation: An Emerging Signaling Pathway
    Jian Q Feng; Fiscal Year: 2013
    ..hypothesis that OSX controls root dentinogenesis through (i) the inhibition of cell proliferation and (ii) the acceleration of cll differentiation via the inhibition of ?-catenin and upregulation of DSPP...
  55. Third International Chordoma Research Workshop: Catalyzing New Advances in Chordo
    EDWARD LES; Fiscal Year: 2011
    ..The rapid worldwide acceleration of chordoma research at an unprecedented pace since the First International Chordoma Research Workshop (ICRW) ..
  56. Molecular mechanisms of notch signaling in maintenance of melanocyte stem cells
    David E Fisher; Fiscal Year: 2012
    ..As acceleration of mitochondria metabolism is the major cause of oxidative stress, we hypothesize that Notch signaling through ..
  57. Neuroimaging Biomarkers for Post-Operative Cognitive Decline in Older Adults
    CATHERINE E PRICE; Fiscal Year: 2013
    ..risk for cognitive decline following major surgeries with this having implications for neurodegenerative acceleration as well as post-operative and long-term care costs...
  58. TP508: A New Drug for Mitigating Lethal Effects of Radiatin Exposure
    Laurie E Sower; Fiscal Year: 2013
    ..clinical trials for healing diabetic foot ulcers and fractures, may prevent RCI-induced mortality based on its acceleration of wound healing and its unique beneficial effects on vascular endothelial cells...
  59. Coral: Central GFR and Biochemistry Laboratory
    Michael W Steffes; Fiscal Year: 2012
    ..ischemia leads to neuroendocdne activation, hypertension, and renal insufficiency potentially resulting in acceleration of therosclerosis, further renal dysfunction, myocardial infarction, stroke and death...
  60. Estrogen Receptor a Regulation of Lupus Development and Pathogenesis
    Karen A Gould; Fiscal Year: 2013
    ..is modulated by ER1, 2) Identify the cell lineage(s) in which ER1 must be expressed to achieve ER1-dependent acceleration of lupus and 3) Identify ER1-regulated processes that promote production of anti-DNA IgG antibodies...
  61. Petascale Molecular Dynamics Data Processing System
    Klaus Schulten; Fiscal Year: 2010
    ..be enabled through two large shared memory (256 gigabytes each) servers and through graphics processing unit acceleration (NVIDIA Teslas with 4 teraFLOP/s single precision floating point arithmetic performance) equivalent to hundreds ..
  62. The role of dynamic changes in repolarization and calcium transients in Long QT r
    Bum Rak Choi; Fiscal Year: 2013
    ..In addition, heart rate variation such as short-long-short cycle length (pause-dependent mode) or acceleration of heart rates often precedes TdPs formation, suggesting that generation of EADs and dispersion of ..
  63. Visualization of Pelvic Floor Reflexes
    CHRISTOS EURIPIDES CONSTANTINOU; Fiscal Year: 2010
    ..Principal among these parameters, and in addition to the mechanical closure forces are displacement, velocity, acceleration and the trajectory of pelvic floor landmarks...
  64. Neuroligin Regulation of Central GABAergic Synapses
    Zhanyan Fu; Fiscal Year: 2010
    ..will pursue three specific aims: (1) To determine whether altered GABAAR subunit composition accounts for the acceleration in decay time of GABAergic synaptic currents induced by NL2;(2) To define the intracellular domains of NL2 that ..
  65. C/EBP Regulation of Dentinogenesis
    John Harrison; Fiscal Year: 2009
    ..C/EBP[unreadable] null mice, in contrast, exhibit a tooth phenotype characterized by a spatial acceleration of incisor differentiation that appears to involve both lingual and labial surfaces...
  66. Acquisition of a Hybrid Quadrupole, Ion Mobility Separation, Orthogonal Accelerat
    Sheng Zhang; Fiscal Year: 2009
    ..application requests support for the acquisition of a hybrid Quadrupole, Ion Mobility separation, orthogonal acceleration Time-of-Flight Tandem Mass Spectrometer (Synapt HDMS), interfaced with a fully integrated ultra-high ..
  67. A RuleFit Product for Classification and Regression
    DAN STEINBERG; Fiscal Year: 2007
    ..The increased accuracy of the new methods and the acceleration they provide to the analysis of complex data are fueling demand for this new technology...
  68. Slowing of Transit - The Third Enteric Function of 5-HT
    Henry Lin; Fiscal Year: 2005
    ..efforts over the past 100 years have been directed at the peristaltic reflex, which is responsible for the acceleration of intestinal transit and are known to be mediated by 5-HT...
  69. Signals Regulating Vestibular Endolymph Homeostasis
    Mark Henkemeyer; Fiscal Year: 2005
    ..components of the inner ear are fluid-filled chambers that function to detect sound waves and gravity/acceleration/movement, respectively...
  70. Functional Domains of Coagulation Factor V
    Michael Kalafatis; Fiscal Year: 2007
    ..Incorporation of factor Va into prothrombinase and its interaction with factor Xa results in a 300,000-fold acceleration of the catalytic efficiency of the enzyme as compared to the catalysis of the reaction by factor Xa alone...
  71. Long-term Ambulatory Gait Monitor for Parkinson's Disease
    Steven Moore; Fiscal Year: 2007
    ..Linear acceleration and angular velocity of the measured leg are processed by SAGE software (SAGE-S) to provide an accurate measure ..
  72. Opioid-Mediated Fas Expression in Lymphocyte Apoptosis
    Yufang Shi; Fiscal Year: 2005
    ..Several factors including microgravity, lack of load-bearing, stress, acceleration forces, and irradiation have been proposed to contribute to the changes of the immune system...
  73. WOUND HEALING ACCELERATION USING NATURAL PRODUCTS
    Gerald Hammond; Fiscal Year: 1999
    ..abstract_text> ..
  74. EXPLOSION HAZARDS RELATED TO COMBUSTIBLE DUSTS
    CHARLES KAUFFMAN; Fiscal Year: 1992
    ..Two unique combustion facilities have been developed -- a Premixed Turbulent Combustion Bomb (PTCB) and a Flame Acceleration Tube (FAT)...
  75. Shear Stress & Cellular Control of Capillary Function
    Donna Williams; Fiscal Year: 2005
    ..The mechanical stimuli of interest are fluid shear stress and fluid acceleration, two forces imparted to the capillary wall by flowing blood...
  76. HEAD IMPACT RECORDING TECHNOLOGY FOR FIELD APPLICATIONS
    Richard Greenwald; Fiscal Year: 2001
    ..proposal is to research the technical and commercial feasibility of a cost-effective device that measures head acceleration and head impact frequency for widespread use in sports...
  77. Renal Senescence and Transplantation
    Bryan Myers; Fiscal Year: 2007
    ..We now propose to elucidate the relationship between renal senescence and acceleration of chronic allograft nephropathy (CAN) in recipients of aged cadaveric transplants...