sound

Summary

Top Publications

  1. ncbi Improvement of visual contrast detection by a simultaneous sound
    Michael Lippert
    Max Planck Institute for Biological Cybernetics, Spemannstrasse 38, 72076 Tubingen, Germany
    Brain Res 1173:102-9. 2007
  2. pmc Neural modulation tuning characteristics scale to efficiently encode natural sound statistics
    Francisco A Rodriguez
    Department of Electrical and Computer Engineering, University of Connecticut, Storrs, CT 06269 1157, USA
    J Neurosci 30:15969-80. 2010
  3. ncbi The effects of anthropogenic sources of sound on fishes
    A N Popper
    Department of Biology and Center for Comparative and Evolutionary Biology of Hearing, University of Maryland, College Park, MD 20742, USA
    J Fish Biol 75:455-89. 2009
  4. ncbi Top-down modulation of auditory processing: effects of sound context, musical expertise and attentional focus
    M Tervaniemi
    Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Helsinki, Finland
    Eur J Neurosci 30:1636-42. 2009
  5. ncbi Sound generation in the searobin (Prionotus carolinus), a fish with alternate sonic muscle contraction
    Martin A Connaughton
    Washington College, Department of Biology, 300 Washington Ave, Chestertown, MD 21620, USA
    J Exp Biol 207:1643-54. 2004
  6. ncbi Mechanisms of sound localization in mammals
    Benedikt Grothe
    Division of Neurobiology, Department of Biology II, Ludwig Maximilians Universitaet, Munich, Germany
    Physiol Rev 90:983-1012. 2010
  7. ncbi A critical review of the neurophysiological evidence underlying clinical vestibular testing using sound, vibration and galvanic stimuli
    Ian S Curthoys
    Vestibular Research Laboratory, School of Psychology, A 18, The University of Sydney, Sydney, NSW 2006, Australia
    Clin Neurophysiol 121:132-44. 2010
  8. pmc A differentially amplified motion in the ear for near-threshold sound detection
    Fangyi Chen
    Oregon Hearing Research Center, Oregon Health and Science University, Portland, Oregon, USA
    Nat Neurosci 14:770-4. 2011
  9. ncbi Efficient auditory coding
    Evan C Smith
    Department of Psychology, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, Pennsylvania 15213, USA
    Nature 439:978-82. 2006
  10. pmc Multiplexed and robust representations of sound features in auditory cortex
    Kerry M M Walker
    Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK
    J Neurosci 31:14565-76. 2011

Detail Information

Publications348 found, 100 shown here

  1. ncbi Improvement of visual contrast detection by a simultaneous sound
    Michael Lippert
    Max Planck Institute for Biological Cybernetics, Spemannstrasse 38, 72076 Tubingen, Germany
    Brain Res 1173:102-9. 2007
    ..While several studies demonstrate that the presentation of a simultaneous sound can enhance visual detection performance or increase the perceived luminance of a dim light, the origin of these ..
  2. pmc Neural modulation tuning characteristics scale to efficiently encode natural sound statistics
    Francisco A Rodriguez
    Department of Electrical and Computer Engineering, University of Connecticut, Storrs, CT 06269 1157, USA
    J Neurosci 30:15969-80. 2010
    ..Here we characterized the spectrotemporal modulation statistics of several natural sound ensembles and examined how neurons encode these statistics in the central nucleus of the inferior colliculus (CNIC)..
  3. ncbi The effects of anthropogenic sources of sound on fishes
    A N Popper
    Department of Biology and Center for Comparative and Evolutionary Biology of Hearing, University of Maryland, College Park, MD 20742, USA
    J Fish Biol 75:455-89. 2009
    There is increasing concern about the effects of pile driving and other anthropogenic (human-generated) sound on fishes...
  4. ncbi Top-down modulation of auditory processing: effects of sound context, musical expertise and attentional focus
    M Tervaniemi
    Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Helsinki, Finland
    Eur J Neurosci 30:1636-42. 2009
    By recording auditory electrical brain potentials, we investigated whether the basic sound parameters (frequency, duration and intensity) are differentially encoded among speech vs...
  5. ncbi Sound generation in the searobin (Prionotus carolinus), a fish with alternate sonic muscle contraction
    Martin A Connaughton
    Washington College, Department of Biology, 300 Washington Ave, Chestertown, MD 21620, USA
    J Exp Biol 207:1643-54. 2004
    ..searobin (Prionotus carolinus) contracts its paired sonic muscles alternately rather than simultaneously during sound production...
  6. ncbi Mechanisms of sound localization in mammals
    Benedikt Grothe
    Division of Neurobiology, Department of Biology II, Ludwig Maximilians Universitaet, Munich, Germany
    Physiol Rev 90:983-1012. 2010
    The ability to determine the location of a sound source is fundamental to hearing...
  7. ncbi A critical review of the neurophysiological evidence underlying clinical vestibular testing using sound, vibration and galvanic stimuli
    Ian S Curthoys
    Vestibular Research Laboratory, School of Psychology, A 18, The University of Sydney, Sydney, NSW 2006, Australia
    Clin Neurophysiol 121:132-44. 2010
    In addition to activating cochlear receptors, air conducted sound (ACS) and bone conducted vibration (BCV) activate vestibular otolithic receptors, as shown by neurophysiological evidence from animal studies--evidence which is the ..
  8. pmc A differentially amplified motion in the ear for near-threshold sound detection
    Fangyi Chen
    Oregon Hearing Research Center, Oregon Health and Science University, Portland, Oregon, USA
    Nat Neurosci 14:770-4. 2011
    ..In guinea pigs, behavioral measurements indicate a minimum detectable sound pressure of ∼20 μPa at 16 kHz. Such faint sounds produce 0...
  9. ncbi Efficient auditory coding
    Evan C Smith
    Department of Psychology, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, Pennsylvania 15213, USA
    Nature 439:978-82. 2006
    ..These results indicate that the auditory code might approach an information theoretic optimum and that the acoustic structure of speech might be adapted to the coding capacity of the mammalian auditory system...
  10. pmc Multiplexed and robust representations of sound features in auditory cortex
    Kerry M M Walker
    Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK
    J Neurosci 31:14565-76. 2011
    ..Finally, we observed that formant information is encoded in cortex earlier than pitch information, and we show that this time course matches ferrets' behavioral reaction time differences on a change detection task...
  11. ncbi A neural code for low-frequency sound localization in mammals
    D McAlpine
    MRC Institute of Hearing Research, Science Road, University of Nottingham, Nottingham NG7 2RD, UK
    Nat Neurosci 4:396-401. 2001
    We report a systematic relationship between sound-frequency tuning and sensitivity to interaural time delays for neurons in the midbrain nucleus of the inferior colliculus; neurons with relatively low best frequencies (BFs) showed ..
  12. pmc Perceptual organization of sound begins in the auditory periphery
    Daniel Pressnitzer
    Laboratoire Psychologie de la Perception, Centre National de la Recherche Scientifique and Université Paris Descartes, Paris F 75006, France
    Curr Biol 18:1124-8. 2008
    ....
  13. ncbi The neural network of phantom sound changes over time: a comparison between recent-onset and chronic tinnitus patients
    Sven Vanneste
    TRI Tinnitus Clinic, Brai n, TRI and Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, 2650 Edegem, Belgium
    Eur J Neurosci 34:718-31. 2011
    Tinnitus is characterized by an ongoing conscious perception of a sound in the absence of any external sound source. Chronic tinnitus is notoriously characterized by its resistance to treatment...
  14. pmc Cortical representation of natural complex sounds: effects of acoustic features and auditory object category
    Amber M Leaver
    Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC 20057, USA
    J Neurosci 30:7604-12. 2010
    ..Although specialized voice and speech-sound regions have been proposed, it is unclear how other types of complex natural sounds are processed within this ..
  15. ncbi Sound categories are represented as distributed patterns in the human auditory cortex
    Noel Staeren
    Faculty of Psychology and Neuroscience, Department of Cognitive Neuroscience, University of Maastricht, 6200 MD Maastricht, The Netherlands
    Curr Biol 19:498-502. 2009
    ..b>Sound recognition in the human brain has been assumed to proceed through several functionally specialized areas, ..
  16. ncbi Three-dimensional finite element modeling of human ear for sound transmission
    Rong Z Gan
    School of Aerospace and Mechanical Engineering, University of Oklahoma, Norman, OK 73019, USA
    Ann Biomed Eng 32:847-59. 2004
    An accurate, comprehensive finite element model of the human ear can provide better understanding of sound transmission, and can be used for assessing the influence of diseases on hearing and the treatment of hearing loss...
  17. pmc Sound texture perception via statistics of the auditory periphery: evidence from sound synthesis
    Josh H McDermott
    Howard Hughes Medical Institute, New York University, New York, NY 10003, USA
    Neuron 71:926-40. 2011
    Rainstorms, insect swarms, and galloping horses produce "sound textures"--the collective result of many similar acoustic events...
  18. pmc White matter anisotropy in the ventral language pathway predicts sound-to-word learning success
    Francis C K Wong
    The Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois 60208, USA
    J Neurosci 31:8780-5. 2011
    According to the dual stream model of auditory language processing, the dorsal stream is responsible for mapping sound to articulation and the ventral stream plays the role of mapping sound to meaning...
  19. ncbi Dissociating the representation of action- and sound-related concepts in middle temporal cortex
    Markus Kiefer
    University of Ulm, Department of Psychiatry, Germany
    Brain Lang 122:120-5. 2012
    ..Neuroimaging studies found, in different subject groups, that action-related and sound-related concepts activated different parts of posterior middle temporal gyrus (pMTG), suggesting a modality-..
  20. pmc Two GABAA responses with distinct kinetics in a sound localization circuit
    Zheng Quan Tang
    Department of Anatomy and Neurobiology, College of Medicine, Northeast Ohio Medical University, Rootstown, OH 44272, USA
    J Physiol 590:3787-805. 2012
    ..mechanisms in neurons of the chicken nucleus laminaris (NL), the first encoder of interaural time difference for sound localization in birds...
  21. pmc Serum testosterone, sex hormone-binding globulin and total calcium levels predict the calcaneal speed of sound in men
    Kok Yong Chin
    Pharmacology Department, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
    Clinics (Sao Paulo) 67:911-6. 2012
    ..The present study aimed to examine the relationship between the calcaneal speed of sound and biochemical determinants of bone mass, such as sex hormones, parathyroid hormones and serum calcium.
  22. pmc Direction of visual apparent motion driven solely by timing of a static sound
    Elliot Freeman
    Department of Psychology, Brunel University, Uxbridge, UB8 3PH, United Kingdom
    Curr Biol 18:1262-6. 2008
    ..We investigated whether timing of a static sound can also influence spatio-temporal processing of visual apparent motion, induced here by visual bars alternating ..
  23. ncbi Sound representation methods for spectro-temporal receptive field estimation
    Patrick Gill
    Biophysics Group, University of California at Berkeley, 3210, Tolman Hall, Berkeley, CA, 94720, USA
    J Comput Neurosci 21:5-20. 2006
    The spectro-temporal receptive field (STRF) of an auditory neuron describes the linear relationship between the sound stimulus in a time-frequency representation and the neural response...
  24. ncbi A noisy spring: the impact of globally rising underwater sound levels on fish
    Hans Slabbekoorn
    Behavioural Biology, Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands
    Trends Ecol Evol 25:419-27. 2010
    ..Here we call attention to the urgent need to study the role of sound in the lives of fish and to develop a better understanding of the ecological impact of anthropogenic noise.
  25. ncbi Preperceptual and stimulus-selective enhancement of low-level human visual cortex excitability by sounds
    Vincenzo Romei
    Centre for Cognitive Neuroimaging, Department of Psychology, University of Glasgow, Glasgow G128QB, UK
    Curr Biol 19:1799-805. 2009
    ..we show that structured looming sounds considerably enhance visual cortex excitability relative to other sound categories and white-noise controls...
  26. pmc A rate code for sound azimuth in monkey auditory cortex: implications for human neuroimaging studies
    Uri Werner-Reiss
    Department of Psychology and Neuroscience, Center for Cognitive Neuroscience, Duke University, Durham, North Carolina 27708, USA
    J Neurosci 28:3747-58. 2008
    Is sound location represented in the auditory cortex of humans and monkeys? Human neuroimaging experiments have had only mixed success at demonstrating sound location sensitivity in primary auditory cortex...
  27. pmc A population rate code of auditory space in the human cortex
    Nelli H Salminen
    Department of Biomedical Engineering and Computational Science, Helsinki University of Technology, Helsinki, Finland
    PLoS ONE 4:e7600. 2009
    Previous work on the human auditory cortex has revealed areas specialized in spatial processing but how the neurons in these areas represent the location of a sound source remains unknown.
  28. ncbi Human middle-ear sound transfer function and cochlear input impedance
    R Aibara
    Department of Veterans Affairs Medical Center, 3801 Miranda Ave, MC 112-B1, Palo Alto, CA 94304, USA
    Hear Res 152:100-9. 2001
    The middle-ear pressure gain, defined as the ear canal sound pressure to cochlear vestibule pressure gain, GME, and the ear canal sound pressure to stapes footplate velocity transfer function, SVTF, simultaneously measured in 12 fresh ..
  29. ncbi Echolocation clicks of two free-ranging, oceanic delphinids with different food preferences: false killer whales Pseudorca crassidens and Risso's dolphins Grampus griseus
    P T Madsen
    Ocean Alliance, 191 Western Road, Lincoln, MA 01773, USA
    J Exp Biol 207:1811-23. 2004
    ..captive animals have accumulated a large body of knowledge concerning the production, reception and processing of sound in odontocete biosonars, but there is little information about the properties and use of biosonar clicks of free-..
  30. ncbi Confrontation naming of environmental sounds
    M M Marcell
    Department of Psychology, College of Charleston, Charleston, SC 29424, USA
    J Clin Exp Neuropsychol 22:830-64. 2000
    ..1, criteria for scoring naming accuracy were developed and rating data were gathered on degree of confidence in sound identification and the perceived familiarity, complexity, and pleasantness of the sounds...
  31. ncbi Temporal ventriloquism: sound modulates the flash-lag effect
    Jean Vroomen
    Department of Psychology, Tilburg University, Tilburg, Netherlands
    J Exp Psychol Hum Percept Perform 30:513-8. 2004
    A sound presented in close temporal proximity to a visual stimulus can alter the perceived temporal dimensions of the visual stimulus (temporal ventriloquism)...
  32. ncbi Large-scale heterogeneous representation of sound attributes in rat primary auditory cortex: from unit activity to population dynamics
    Takeshi Ogawa
    Department of Functional Brain Imaging and Smart Aging International Research Center, Institute of Development, Aging, and Cancer, Tohoku University, Sendai 980 8575, Japan
    J Neurosci 31:14639-53. 2011
    ..indicates the existence of pyramidal cells (PCs) and interneurons with nontrivial tuning characteristics for sound attributes in the primary auditory cortex (A1) of mammals...
  33. pmc An on-chip, multichannel droplet sorter using standing surface acoustic waves
    Sixing Li
    Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA
    Anal Chem 85:5468-74. 2013
    ....
  34. pmc Mice and humans perceive multiharmonic communication sounds in the same way
    Günter Ehret
    Department of Neurobiology, University of Ulm, D 89069 Ulm, Germany
    Proc Natl Acad Sci U S A 99:479-82. 2002
    ....
  35. pmc Inhibitory plasticity in a lateral band improves cortical detection of natural vocalizations
    Edgar E Galindo-Leon
    Department of Biology, Emory University, 1510 Clifton Road NE, Atlanta, GA 30322, USA
    Neuron 62:705-16. 2009
    ....
  36. ncbi The ability to move to a beat is linked to the consistency of neural responses to sound
    Adam Tierney
    Auditory Neuroscience Laboratory, Communication Sciences, Institute for Neuroscience, Neurobiology and Physiology, and Otolaryngology, Northwestern University, Evanston, Illinois 60208
    J Neurosci 33:14981-8. 2013
    ..In particular, links between auditory-motor synchronization ability and characteristics of the brain's response to sound have not yet been explored...
  37. ncbi Auditory perception of natural sound categories--an fMRI study
    M Sharda
    National Brain Research Centre, NH 8, Nainwal Mode, Manesar, Gurgaon, India
    Neuroscience 214:49-58. 2012
    ..While this seems to be an appealing proposition, further studies are required to explore the role of top-down mechanisms arising from such features to drive category selectivity in the brain...
  38. ncbi Auditory attention--focusing the searchlight on sound
    Jonathan B Fritz
    Centre for Auditory and Acoustic Research, Institute for Systems Research, University of Maryland, College Park, MD 20742, USA
    Curr Opin Neurobiol 17:437-55. 2007
    ....
  39. ncbi Single-layer graphene sound-emitting devices: experiments and modeling
    He Tian
    Institute of Microelectronics, Tsinghua University, Beijing, 100084, China
    Nanoscale 4:2272-7. 2012
    Single-layer graphene (SLG) was demonstrated to emit sound. The sound emission from SLG had a significant flat frequency response in the wide ultrasound range from 20 kHz to 50 kHz...
  40. ncbi Graphene-on-paper sound source devices
    He Tian
    Institute of Microelectronics, Tsinghua University, Beijing 100084, China
    ACS Nano 5:4878-85. 2011
    We demonstrate an interesting phenomenon that graphene can emit sound. The application of graphene can be expanded in the acoustic field. Graphene-on-paper sound source devices are made by patterning graphene on paper substrates...
  41. ncbi Asymmetry and dynamics of a narrow sonar beam in an echolocating harbor porpoise
    Jens C Koblitz
    Animal Physiology, Institute for Neurobiology, University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany
    J Acoust Soc Am 131:2315-24. 2012
    A key component in the operation of a biosonar system is the radiation of sound energy from the sound producing head structures of toothed whales and microbats...
  42. ncbi Echolocation signals of wild harbour porpoises, Phocoena phocoena
    Anne Villadsgaard
    Department of Zoophysiology, Institute of Biological Sciences, University of Aarhus, C F Møllers Alle, DK 8000 Aarhus C, Denmark
    J Exp Biol 210:56-64. 2007
    ..Harbour porpoises in this study preferred a relatively constant inter-click interval of about 60 ms, but intervals up to 200 ms and down to 30 ms were also recorded...
  43. pmc Systematic mapping of the monkey inferior colliculus reveals enhanced low frequency sound representation
    David A Bulkin
    Department of Neurobiology, Duke University, Durham, NC 27708, USA
    J Neurophysiol 105:1785-97. 2011
    ..The remaining 15 (of 100) locations exhibited auditory responses that were not sensitive to sound frequency...
  44. ncbi From symbols to sounds: visual symbolic information activates sound representations
    Andreas Widmann
    Institut für Allgemeine Psychologie, University of Leipzig, Germany
    Psychophysiology 41:709-15. 2004
    ..These results suggest that the auditory system can establish a representation of an expected stimulus on the basis of visual symbolic information...
  45. pmc Reversal to air-driven sound production revealed by a molecular phylogeny of tongueless frogs, family Pipidae
    Iker Irisarri
    Department of Biodiversity and Evolutionary Biology, Museo Nacional de Ciencias Naturales, CSIC, Madrid, Spain
    BMC Evol Biol 11:114. 2011
    ..b>Sound production plays a central role in the behavior of frogs, which use their calls to delimit territories and attract ..
  46. ncbi Potential mechanism of sound production in Oreochromis niloticus (Cichlidae)
    Nicolas Longrie
    Laboratory of Functional and Evolutive Morphology, University of Liege, Liege, Belgium
    J Exp Biol 212:3395-402. 2009
    ..In the present study, a combination of approaches was used to investigate the sound-producing mechanism of Oreochromis niloticus...
  47. ncbi The effects of human-generated sound on fish
    Arthur N Popper
    Department of Biology, University of Maryland, College Park, MD 20742, USA
    Integr Zool 4:43-52. 2009
    There is growing international concern about the effects of human-generated sound on fish and other aquatic organisms...
  48. ncbi Sound strategies: the 65-million-year-old battle between bats and insects
    William E Conner
    Department of Biology, Wake Forest University, Winston Salem, North Carolina 27106, USA
    Annu Rev Entomol 57:21-39. 2012
    ..In an exciting new twist, researchers are taking the technologies developed in the laboratory back into the field, where they are poised to appreciate the full richness of this remarkable predator-prey interaction...
  49. ncbi Interhemispheric differences in auditory processing revealed by fMRI in awake rhesus monkeys
    Olivier Joly
    Laboratorium voor Neuro en Psychofysiologie, K U Leuven Medical School, B 3000 Leuven, Belgium
    Cereb Cortex 22:838-53. 2012
    ..Our results indicate that processing of vocal sounds in the lateral belt and parabelt is asymmetric in monkeys, as predicted from lesion studies...
  50. pmc Adaptive avoidance of reef noise
    Stephen D Simpson
    School of Biological Sciences, University of Bristol, Bristol, United Kingdom
    PLoS ONE 6:e16625. 2011
    ....
  51. ncbi When sound affects vision: effects of auditory grouping on visual motion perception
    K Watanabe
    California Institute of Technology, Mail Code 139 74, Pasadena, CA 91125, USA
    Psychol Sci 12:109-16. 2001
    ..A brief sound at the moment the targets coincide biases perception toward bouncing...
  52. ncbi Corticofugal modulation of midbrain sound processing in the house mouse
    Jun Yan
    Department of Physiology and Biophysics, Neuroscience Research Group, Faculty of Medicine, University of Calgary, 3330 Hospital Drive, N W, Calgary, Alberta, T2N 4N1, Canada
    Eur J Neurosci 16:119-28. 2002
    ..The midbrain processing of sound components in the centre of cortical feedback is largely enhanced while processing in the surround is suppressed.
  53. ncbi Efficient coding of natural sounds
    Michael S Lewicki
    Computer Science Department and Center for the Neural Basis of Cognition, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, Pennsylvania 15213, USA
    Nat Neurosci 5:356-63. 2002
    The auditory system encodes sound by decomposing the amplitude signal arriving at the ear into multiple frequency bands whose center frequencies and bandwidths are approximately exponential functions of the distance from the stapes...
  54. ncbi Practice strategies of musicians modulate neural processing and the learning of sound-patterns
    M Seppanen
    Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
    Neurobiol Learn Mem 87:236-47. 2007
    ..component of event-related brain potentials (ERPs) was used to probe pre-attentive neural discrimination of simple sound features and melody-like patterns...
  55. ncbi Memory-based detection of rare sound feature combinations in anesthetized rats
    Piia Astikainen
    Department of Psychology, University of Jyvaäskylaä, Jyvaäskylaä, Finland
    Neuroreport 17:1561-4. 2006
    It is unclear whether the ability of the brain to discriminate rare from frequently repeated combinations of sound features is limited to the normal sleep/wake cycle...
  56. pmc Imaging hair cell transduction at the speed of sound: dynamic behavior of mammalian stereocilia
    Anders Fridberger
    Center for Hearing and Communication Research, Department of Clinical Neuroscience, Karolinska Institutet, M1 Karolinska Universitetssjukhuset, SE 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 103:1918-23. 2006
    The cochlea contains two types of sensory cells, the inner and outer hair cells. Sound-evoked deflection of outer hair cell stereocilia leads to fast force production that will enhance auditory sensitivity up to 1,000-fold...
  57. ncbi Changes of AI receptive fields with sound density
    David T Blake
    Coleman Laboratory and Keck Center for Integrative Neuroscience, Department of Otolaryngology, University of California, San Francisco, California 94143 0732, USA
    J Neurophysiol 88:3409-20. 2002
    ..Spectral selectivity more than doubled. Inhibitory subfields, which were rarely recorded at low sound densities, emerged at higher sound densities...
  58. pmc Early auditory experience generates long-lasting memories that may subserve vocal learning in songbirds
    Mimi L Phan
    Department of Psychology, Rutgers University, Piscataway, NJ 08854, USA
    Proc Natl Acad Sci U S A 103:1088-93. 2006
    ..Furthermore, the strength of this selectivity shows a striking correlation with the fidelity of vocal imitation, suggesting that this auditory memory may have served as the model for song learning...
  59. ncbi Passive acoustic detection of deep-diving beaked whales
    Walter M X Zimmer
    NATO Undersea Research Centre, Viale San Bartolomeo 400, 19138 La Spezia, Italy
    J Acoust Soc Am 124:2823-32. 2008
    ..7 km, provided the listening duration exceeds the deep dive interval, about 2.5 h on average. Detection ranges beyond 4 km are unlikely and would require low ambient noise or special sound propagation conditions.
  60. pmc Invariance and sensitivity to intensity in neural discrimination of natural sounds
    Cyrus P Billimoria
    Department of Biomedical Engineering, Hearing Research Center, Center for Biodynamics and Program in Mathematical and Computational Neuroscience, Boston University, Boston, Massachusetts 02215, USA
    J Neurosci 28:6304-8. 2008
    ..Our results indicate that a temporally sparse spike timing-based code at a primary cortical stage can provide a substrate for intensity-invariant discrimination of natural sounds...
  61. ncbi Sound processing hierarchy within human auditory cortex
    Hidehiko Okamoto
    Institute for Biomagnetismand Biosignal Analysis, University of Muenster, Malmedyweg 15, 48149 Muenster, Germany
    J Cogn Neurosci 23:1855-63. 2011
    ..present study, we investigated the complex effects of auditory-focused attention and the signal-to-noise ratio of sound stimuli on three different auditory evoked field components (auditory steady-state response, N1m, and sustained ..
  62. ncbi Resonators in insect sound production: how insects produce loud pure-tone songs
    H C Bennet-Clark
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    J Exp Biol 202:3347-57. 1999
    ..The evidence for the existence of resonators in insect sound production is assessed. The mechanics of different types of sound-producing system found in insects is described...
  63. ncbi Reverse propagation of sound in the gerbil cochlea
    Tianying Ren
    Oregon Hearing Research Center, Department of Otolaryngology and Head and Neck Surgery, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, NRC 04, Portland, Oregon 97239 3098, USA
    Nat Neurosci 7:333-4. 2004
    ..These results contradict the current theory and show that the ear emits sounds through the cochlear fluids as compression waves rather than along the basilar membrane as backward-traveling waves...
  64. pmc Cortical FMRI activation to sequences of tones alternating in frequency: relationship to perceived rate and streaming
    E Courtenay Wilson
    Speech and Hearing Bioscience and Technology Program, Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    J Neurophysiol 97:2230-8. 2007
    ..of a sequence and are far greater than the effects produced by changing other physical stimulus variables, such as sound level or bandwidth...
  65. ncbi The sound of stress: blunted cortisol reactivity to psychosocial stress in tinnitus sufferers
    Sylvie Hébert
    Ecole d Orthophonie et d Audiologie, Universite de Montreal, Canada Centre de recherche, Institut Universitaire de Geriatrie de Montreal, Canada
    Neurosci Lett 411:138-42. 2007
    ..Their cortisol response is similar to that found in other bodily stress-related diseases and thus suggests that tinnitus is related to stress. However, tinnitus intensity might not be modulated by stress in a concurrent manner...
  66. ncbi Asymmetric cross-modal effects in time perception
    Kuan Ming Chen
    Department of Psychology, National Taiwan University, No 1, Roosevelt Rd Sec 4, Taipei 10617, Taiwan
    Acta Psychol (Amst) 130:225-34. 2009
    ..We used an oddball paradigm to examine the effect of sound on the judgment of visual duration and that of a visual object on the judgment of an auditory duration...
  67. ncbi Tinnitus in hamsters following exposure to intense sound
    Henry E Heffner
    Department of Psychology, University of Toledo, Toledo, OH 43606, USA
    Hear Res 170:83-95. 2002
    ..procedure to drink in the presence of a broadband noise and/or a tone and to stop drinking in the absence of sound. A variety of tones and loudspeaker locations were used during training so that the animals would respond to a ..
  68. pmc Brain activation during anticipation of sound sequences
    Amber M Leaver
    Laboratory of Integrative Neuroscience and Cognition, Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC 20057, USA
    J Neurosci 29:2477-85. 2009
    Music consists of sound sequences that require integration over time. As we become familiar with music, associations between notes, melodies, and entire symphonic movements become stronger and more complex...
  69. ncbi Audiovisual perception: Implicit estimation of sound-arrival time
    Yoichi Sugita
    National Institute of Advanced Industrial Science and Technology, Teragu hakusan 1497 1, Tsukuba 300 4201, Japan
    Nature 421:911. 2003
  70. ncbi Corticofugal modulation of initial sound processing in the brain
    Feng Luo
    Department of Physiology and Biophysics, Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Neurosci 28:11615-21. 2008
    ..of particular auditory information and attenuates others at the first processing level in the brain based on sound frequencies encoded in the auditory cortex...
  71. ncbi Hyperactivity in the dorsal cochlear nucleus after intense sound exposure and its resemblance to tone-evoked activity: a physiological model for tinnitus
    J A Kaltenbach
    Department of Otolaryngology, Wayne State University, 5E UHC, Detroit, MI 48201, USA
    Hear Res 140:165-72. 2000
    ..This increase may represent an important neural correlate of noise-induced tinnitus, a condition in which sound, typically of very high pitch, is perceived in the absence of a corresponding acoustic stimulus...
  72. pmc Waves on Reissner's membrane: a mechanism for the propagation of otoacoustic emissions from the cochlea
    Tobias Reichenbach
    Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY 10065 6399, USA
    Cell Rep 1:374-84. 2012
    b>Sound is detected and converted into electrical signals within the ear. The cochlea not only acts as a passive detector of sound, however, but can also produce tones itself...
  73. ncbi Mosquito hearing: sound-induced antennal vibrations in male and female Aedes aegypti
    M C Göpfert
    Institute for Zoology, Laboratory of Bioacoustics, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    J Exp Biol 202:2727-38. 1999
    ..As early as 1855, it was proposed that this remarkable antennal anatomy served as a sound-receiving structure...
  74. ncbi Tuning of the ocular vestibular evoked myogenic potential (oVEMP) to AC sound shows two separate peaks
    Alexander S Zhang
    Prince of Wales Clinical School, University of New South Wales, Randwick, Sydney, NSW 2031, Australia
    Exp Brain Res 213:111-6. 2011
    ..When elicited using air-conducted (AC) sound stimulation, the oVEMP is thought to reflect mostly saccular activation...
  75. ncbi Sound-intensity-dependent compensation for the small interaural time difference cue for sound source localization
    Eri Nishino
    Departments of Physiology and Morphological Brain Science, Faculty of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Neurosci 28:7153-64. 2008
    Interaural time difference (ITD) is a major cue for sound source localization. However, animals with small heads experience small ITDs, making ITD detection difficult, particularly for low-frequency sound...
  76. ncbi The remarkable cochlear amplifier
    J Ashmore
    Department of Neuroscience, Physiology and Pharmacology and UCL Ear Institute, Gower Street, London WC1E 6BT, UK
    Hear Res 266:1-17. 2010
    ..These experiments are presently lacking but if successfully performed would have an enormous impact on our understanding of the cochlear amplifier...
  77. ncbi Vestibular-evoked extraocular potentials produced by stimulation with bone-conducted sound
    S M Rosengren
    Institute of Neurological Sciences and UNSW Clinical School, Prince of Wales Hospital Randwick, Sydney, NSW 2031, Australia
    Clin Neurophysiol 116:1938-48. 2005
    ..To investigate the origin, whether ocular or extraocular, of the short latency frontal potential (N15) reported by following vestibular stimulation...
  78. ncbi Sperm whale sound production studied with ultrasound time/depth-recording tags
    P T Madsen
    Department of Zoophysiology, Institute of Biological Sciences, University of Aarhus, Building 131, 8000 Aarhus C, Denmark
    J Exp Biol 205:1899-906. 2002
    ..volumes in diving mammals are reduced with increasing ambient pressure, which seems likely to influence pneumatic sound production at depth...
  79. ncbi Neural encoding and retrieval of sound sequences
    Josef P Rauschecker
    Laboratory of Integrative Neuroscience and Cognition, Georgetown University Medical Center, New Research Building, Room WP15, Box 571460, Washington, DC 20057 1460, USA
    Ann N Y Acad Sci 1060:125-35. 2005
    ..However, the higher auditory and prefrontal areas found to be activated by musical melodies are expected to interact with primary areas in both bottom-up and top-down fashion to bring about the perceptual organization of sound sequences.
  80. pmc Development of gerbil medial superior olive: integration of temporally delayed excitation and inhibition at physiological temperature
    Florin V Chirila
    Sensory Neuroscience Research Center, West Virginia University School of Medicine, One Medical Center Drive, PO Box 9303, Morgantown, WV 26506 9303, USA
    J Physiol 584:167-90. 2007
    ..We propose that shaping of excitatory circuitry to mediate TD sensitivity can begin before airborne sound is detectable, and that inhibitory inputs having suboptimal neural delays may then be pruned by cellular ..
  81. ncbi Functional magnetic resonance imaging of sound pressure level encoding in the rat central auditory system
    Jevin W Zhang
    Laboratory of Biomedical Imaging and Signal Processing The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Neuroimage 65:119-26. 2013
    Intensity is an important physical property of a sound wave and is customarily reported as sound pressure level (SPL)...
  82. ncbi Ocular vestibular evoked myogenic potentials (OVEMPs) produced by air- and bone-conducted sound
    Neil P McAngus Todd
    Faculty of Life Science, University of Manchester, Manchester M60 1QD, UK
    Clin Neurophysiol 118:381-90. 2007
    ..To determine the origin and properties of short latency extraocular potentials produced by activation of the vestibular apparatus using two modes of acoustic stimulation...
  83. pmc Pilot whales attracted to killer whale sounds: acoustically-mediated interspecific interactions in cetaceans
    Charlotte Curé
    Sea Mammal Research Unit, School of Biology, University of St Andrews, Fife, St Andrews, United Kingdom
    PLoS ONE 7:e52201. 2012
    ..sounds to pilot whales induced a clear increase in group size and a strong attraction of the animals towards the sound source...
  84. ncbi Affective ratings of sound stimuli
    Jaime Redondo
    University of Santiago, Santiago de Compostela, Spain
    Behav Res Methods 40:784-90. 2008
    ..J. Lang, Bradley, & Cuthbert, 1999; Moltó et al., 1999) and the Affective Norms for English Words (Bradley & Lang, 1999a; Redondo, Fraga, Padrón, & Comesaña, 2007)...
  85. ncbi Tuning to natural stimulus dynamics in primary auditory cortex
    J A Garcia-Lazaro
    University Laboratory of Physiology, Parks Road, Oxford OX1 3PT, United Kingdom
    Curr Biol 16:264-71. 2006
    ..These findings indicate that auditory cortex is indeed tuned to the 1/f dynamics commonly found in the statistical distributions of natural soundscapes...
  86. ncbi Sound radiation around a flying fly
    Jérôme Sueur
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, United Kingdom
    J Acoust Soc Am 118:530-8. 2005
    ..recording, we describe both the directional radiation pattern and the detailed frequency composition of the sound produced by a tethered flying (Lucilia sericata)...
  87. pmc Comparison of forward (ear-canal) and reverse (round-window) sound stimulation of the cochlea
    Christof Stieger
    Department of Otology and Laryngology, Harvard Medical School, Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    Hear Res 301:105-14. 2013
    The cochlea is normally driven with "forward" stimulation, in which sound is introduced to the ear canal. Alternatively, the cochlea can be stimulated at the round window (RW) using an actuator...
  88. ncbi The role of male courtship song in species recognition in Drosophila montana
    M Saarikettu
    Department of Genetics, University of Oulu, Oulu, Finland
    Behav Genet 35:257-63. 2005
    ..In Drosophila montana, specific traits of the courtship song (the length and the carrier frequency of sound pulses) have earlier been shown to play an important role in intraspecific mate choice...
  89. ncbi Tuning of the ocular vestibular evoked myogenic potential to bone-conducted sound stimulation
    Alexander S Zhang
    Prince of Wales Clinical School, University of New South Wales, Randwick, Sydney, New South Wales, Australia
    J Appl Physiol (1985) 112:1279-90. 2012
    ..The findings are consistent with an effect on a receptor with a resonance around 100 Hz, most likely the utricle...
  90. pmc Wall-corner classification using sonar: a new approach based on geometric features
    Milagros Martinez
    Instituto de Automática e Informática Industrial ai2 1, Universidad Politecnica de Valencia, C de Vera, S N, 46022, Valencia, Spain
    Sensors (Basel) 10:10683-700. 2010
    ..5 to 4 m, and with incidence angles ranging between 20° to 70°. Experimental results show an enhancement on the success in classification rates when these geometric features are considered...
  91. pmc Specialization of primary auditory cortex processing by sound exposure in the "critical period"
    Haruka Nakahara
    Keck Center for Integrative Neuroscience, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:7170-4. 2004
    ..In the sound exposure-revised A1, responses were segregated into two explicit zones representing spectrally and temporally ..
  92. ncbi Active traveling wave in the cochlea
    Thomas Duke
    Cavendish Laboratory, Madingley Road, Cambridge CB3 0HE, United Kingdom
    Phys Rev Lett 90:158101. 2003
    A sound stimulus entering the inner ear excites a deformation of the basilar membrane which travels along the cochlea towards the apex. It is well established that this wavelike disturbance is amplified by an active system...
  93. pmc Zipf's law in short-time timbral codings of speech, music, and environmental sound signals
    Martín Haro
    Music Technology Group, Universitat Pompeu Fabra, Barcelona, Spain
    PLoS ONE 7:e33993. 2012
    ..Finally, we find that a Yule-Simon process with memory provides a reasonable quantitative approximation for our data, suggesting the existence of a common simple generative mechanism for all considered sound sources.
  94. ncbi Responses of ventral cochlear nucleus neurons to contralateral sound after conductive hearing loss
    Christian J Sumner
    Kresge Hearing Research Institute, Ann Arbor, Michigan 48109 0506, USA
    J Neurophysiol 94:4234-43. 2005
    ..In normal hearing animals, contralateral sound produces an inhibitory response to broadband noise in approximately one third of ventral cochlear nucleus (VCN) ..
  95. ncbi Sound strategy: acoustic aposematism in the bat-tiger moth arms race
    Nickolay I Hristov
    Department of Biology, Wake Forest University, Winston Salem, NC 27109, USA
    Naturwissenschaften 92:164-9. 2005
    ..ornatrix, and Apantesis nais, that naturally differ in their levels of unpalatability and their ability to produce sound. Moths were tethered and offered to free-flying naive big brown bats, Eptesicus fuscus...
  96. pmc Nonlinear spectrotemporal interactions underlying selectivity for complex sounds in auditory cortex
    Srivatsun Sadagopan
    Laboratory of Auditory Neurophysiology, Departments of Neuroscience and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 29:11192-202. 2009
    ..neurons in the primary auditory cortex (A1) of awake marmoset monkeys were in fact highly selective for complex sound features...
  97. pmc Accurate sound localization in reverberant environments is mediated by robust encoding of spatial cues in the auditory midbrain
    Sasha Devore
    Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Neuron 62:123-34. 2009
    In reverberant environments, acoustic reflections interfere with the direct sound arriving at a listener's ears, distorting the spatial cues for sound localization...
  98. ncbi The influence of lifelong musicianship on neurophysiological measures of concurrent sound segregation
    Benjamin Rich Zendel
    Rotman Research Institute, Toronto, Canada
    J Cogn Neurosci 25:503-16. 2013
    ..Here, we investigated the impact of lifelong musicianship on concurrent sound segregation and perception using scalp-recorded ERPs...
  99. ncbi How learning to shake a rattle affects 8-month-old infants' perception of the rattle's sound: electrophysiological evidence for action-effect binding in infancy
    Markus Paulus
    Donders Institute for Brain, Cognition, and Behaviour, Radboud University Nijmegen, The Netherlands
    Dev Cogn Neurosci 2:90-6. 2012
    ..To investigate this, we trained 8-month-old infants for one week to use a novel rattle that produced a specific sound when shaken. Infants were also presented with another sound, which was not related to an action...
  100. ncbi Transmission properties of bone conducted sound: measurements in cadaver heads
    Stefan Stenfelt
    Department of Otolaryngology Head and Neck Surgery, Stanford University Medical Center, Stanford, California 92305 5328, USA
    J Acoust Soc Am 118:2373-91. 2005
    ..In this paper, the transmission properties of bone conducted sound in human head are presented, measured as the three-dimensional vibration at the cochlear promontory in six intact ..
  101. ncbi Auditory streaming of amplitude-modulated sounds in the songbird forebrain
    Naoya Itatani
    Animal Physiology and Behaviour Group, Institute for Biology and Environmental Sciences, Carl von Ossietzky University Oldenburg, 26111 Oldenburg, Germany
    J Neurophysiol 101:3212-25. 2009
    ..These two effects are additive and may provide the basis for a more separated representation of A and B signals by two populations of neurons that can be viewed as a neuronal correlate of segregated streams...

Research Grants70

  1. HUMAN MIDDLE EAR--FORWARD AND REVERSE SOUND TRANSMISSION
    Sunil Puria; Fiscal Year: 2002
    This project seeks to characterize forward and reverse sound transmission through the human middle ear...
  2. Intervention for Reduced Sound Tolerance
    C Formby; Fiscal Year: 2006
    The objective of this five-year research project is to evaluate an innovative intervention for reduced sound tolerance (i.e., hyperacusis) for hearing impaired persons...
  3. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2012
    ..Federal agencies require that all test methods should be based on sound science...
  4. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2011
    ..Federal agencies require that all test methods should be based on sound science...
  5. Infant Screening and Diagnosis of Duchenne Muscular Dys*
    Paul Fernhoff; Fiscal Year: 2007
    ..While making a sound argument of the merits of newborn screening for DMD (including: 1) avoidance of the "diagnostic odyssey" of ..
  6. Behavioral Activation Therapy for Rural Veterans with Diabetes and Depression
    Aanand Dinkar Naik; Fiscal Year: 2013
    ..who is chairing the data safety monitoring committee), and bi-annual meetings of the full advisory board is sound. The dissemination and implementation plan is innovative and is a major strength...
  7. Targeting Inflammation for the Amelioration of Cisplatin-Hearing Loss
    Vickram Ramkumar; Fiscal Year: 2011
    ..cisplatin produces inflammation in the inner ear and this leads to death of cells responsible for transmission of sound in the inner ear...
  8. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2009
    ..Federal agencies require that all test methods should be based on sound science...
  9. Trichothecene Toxicity and the Ribotoxic Stress Response
    James J Pestka; Fiscal Year: 2012
    ..Collectively, these outcomes will positively impact public health by providing a scientific basis for generating sound recommendations relative to this important class of toxins and appropriate remedial actions should exposure occur...
  10. Targeting iNOS to inhibit myeloid-derived suppressor cells (MDSC) in melanoma
    ANDREW GREGORY SIKORA; Fiscal Year: 2013
    ..our understanding of the relationship between inflammation and tumor-mediated immunosuppression, and provide a sound platform for establishing an independent research career in cancer immunology and translational cancer biology...
  11. Functional Neuroimaging of Individual Differences in Affect and Motivation
    BRIAN JAMES MICKEY; Fiscal Year: 2013
    ..he employed electrophysiology and computational techniques to study activity in the cerebral cortex that underlies sound perception, and in a related study, he investigated auditory processing in schizophrenia...
  12. Human middle-ear imaging, physiology, and biomechanics
    CHARLES RICHARD STEELE; Fiscal Year: 2013
    ..of hearing, yet there is currently a lack of knowledge about the mechanisms of high-frequency middle-ear sound transmission in mammals...
  13. Endotoxin, the airway transcriptome, and obstructive lung disease
    PEGGY SUE LAI; Fiscal Year: 2013
    ..These studies take advantage of the sound study infrastructure present in two already existing and unique cohort studies, and will provide novel insights ..
  14. A Rodent Model to Study Links Among Diet, Visceral Adipose and Cardiomyopathy
    MELINDA ANN FRYE; Fiscal Year: 2013
    ..Drs. Pagliassotti and Orton, as her mentoring team, will provide sound guidance in the areas of metabolism, obesity and cardiomyopathy...
  15. Epigenetic downregulation of the antibody response and inhibition of autoimmunity
    Paolo Casali; Fiscal Year: 2013
    ..it is exquisitely translational, as (at the time when expensive biologics enter clinical trials) it provies a sound mechanistic basis for use of inexpensive and available epigenetic modulators as therapeutics in autoimmune ..
  16. Validation of microRNAs as therapeutic targets in hematological malignancies
    Natarajan Muthusamy; Fiscal Year: 2013
    ..miRs), short RNA sequences that by hybridizing to target RNAs regulate their translation rate, has offered a sound alternative to the antisense DNA oligonucleotides...
  17. Iyengar yoga for adolescents and young adults with irritable bowel syndrome
    Subhadra Evans; Fiscal Year: 2013
    ..will enable me to begin a program of research that will implement a series of high quality, methodologically sound clinical trials on yoga to understand both mechanistic processes and key predictors of clinical outcomes to ..
  18. Safety signal learning in Rhesus monkeys following early life stressChallenge Ar
    MICHAEL NMN DAVIS; Fiscal Year: 2010
    ..In fact, we now have evidence that the inability to inhibit fear may be a unique biomarker of PTSD. Thus the sound of a car back firing or the smell of sulfur can lead to an intense fear reaction in Viet Nam veterans many years ..
  19. IDENTIFICATION OF ACOUSTICO-LATERALIS TRANSMITTERS
    Dennis G Drescher; Fiscal Year: 2013
    ..Release, a criterion of neurotransmitter identification, will be investigated in response to sound stimulus in vivo...
  20. Role of Subdiaphragmatic Vagus in Fibromyalgia Syndrome
    JON DAVID LEVINE; Fiscal Year: 2013
    ..in the pathophysiological mechanism of generalized hyperalgesia, we found that rats exposed to non-habituating sound stress exhibited a marked increase in hyperalgesia evoked by injection of the pronociceptive inflammatory mediator ..
  21. New Molecular and Cellular Mechanisms of Glaucoma
    Andrei Surguchov; Fiscal Year: 2013
    ..Approximately 4 million Americans have glaucoma and 120,000 are blind because of glaucoma. There is sound medical-scientific evidence that indicates that open-angle glaucoma can be related to relevant service rendered by ..
  22. Biologic Activities of IL-36 Cytokines in Psoriasis
    Andrew Johnston; Fiscal Year: 2013
    ..I have a sound foundation in psoriasis immunology and the training outlined in this proposal will allow me to achieve these five-..
  23. Matrix Otopathology
    MICHAEL ANNE NMI GRATTON; Fiscal Year: 2011
    ..This hypothesis is tested by depleting strial energy reserves with intense, but non-damaging, sound stimulation...
  24. Effects of nerve demyelination on auditory synaptic functions
    Jun Hee Kim; Fiscal Year: 2012
    ..This nerve terminal is involved in a special neuronal circuit that computes the location of sound sources for the auditory system...
  25. Classical and non-classical responses to vitamin D in children: the role of DBP g
    Thomas O Carpenter; Fiscal Year: 2010
    ..before and after vitamin D supplementation, this study will provide data for establishing physiologically sound recommendations for safe, effective vitamin D supplementation in children...
  26. Molecular pathogenesis and genetic diversification of childhood falciparum malari
    STEVE MYER TAYLOR; Fiscal Year: 2013
    ..malaria control will require a new generation of therapeutic and preventive malaria measures that are based on a sound understanding of malaria pathogenesis...
  27. Perinatal Assessment of At-Risk Populations
    William P Fifer; Fiscal Year: 2013
    ..fetal movement and heart rate coupling, patterns of heart rate variability and fetal heart rate response to sound. This new technology will also allow access to markers of perinatal autonomic function in both time and frequency ..
  28. Foot Bone Motion in End Stage Ankle Arthritis Patients
    William R Ledoux; Fiscal Year: 2012
    ..Within the VA Puget Sound Health Care System alone it is estimated that between 17,000 and 38,500 veterans are affected by ankle OA (based ..
  29. CODING IN AUDITORY NEURONS: EFFECTS OF AMINO ACIDS
    Donald M Caspary; Fiscal Year: 2013
    ..In many species, sound exposure, chemical or physical peripheral trauma alters physiologic responses and markers of adult inhibitory ..
  30. Functional Consequence of Macrolide Resistance Mutations in T. pallidum
    Sheila A Lukehart; Fiscal Year: 2012
    ..The results of our work will provide an evidence base on which sound treatment recommendations can be made...
  31. Brain changes in tinnitus
    Josef P Rauschecker; Fiscal Year: 2010
    Tinnitus, a mostly whistling, buzzing, or hissing phantom sound perceived in the absence of a corresponding external stimulus, is perceived by about 15% of the adult population, and about 75% of all patients with hearing loss...
  32. Myosin 15:Genetics, Pathology and Therapeutic Potential
    Sally A Camper; Fiscal Year: 2013
    ..These studies laid a sound foundation for the goals of this grant...
  33. NAPS2 Continuation Genome Wide Association Study of Pancreatitis
    DAVID CLEMENT WHITCOMB; Fiscal Year: 2011
    ..The NAPS2 program represents a sound investment toward addressing several NIDDK research goals and offers an exceptional framework for training the ..
  34. INTRACOCHLEAR ELECTROCHEMICAL GRADIENTS
    Alexander A Spector; Fiscal Year: 2012
    ..These studies will reveal the frequency response of the motor and show how sound is amplified at high frequencies in the inner ear...
  35. Determinants of developing efferent synapses in the mammalian cochlea
    ISABELLE CATHERINA ROUX; Fiscal Year: 2013
    ..significantly influencing sensitivity and frequency selectivity of the cochlea, and most likely playing a role in sound protection...
  36. Health-Seeking Behaviors among Men with Criminal Justice and Substance Abuse Hist
    Pamela Valera; Fiscal Year: 2013
    ..Specific training objectives are: 1) to become proficient in the development, design, and use of psychometrically-sound instruments to measure health-seeking behavior among high-risk, socioeconomically disadvantaged men;2) to gain ..
  37. Improving Air Quality for Laboratory Animal Research
    Sharron S Quisenberry; Fiscal Year: 2010
    ..Although the building is structurally sound, the mechanical system is aged, energy inefficient and is connected to the air handling system used for the ..
  38. P63/IGFBP3/BCL2 Control of Corneal Epithelial Homeostasis
    Danielle M Robertson; Fiscal Year: 2011
    ..Therefore, in order to provide a rational and sound approach to the development and treatment of environmental stresses and disease, it is critically important to ..
  39. Free Hemoglobin Potentiates Pulmonary Vascular Dysfunction in Acute Lung Injury
    JULIE ANNE BASTARACHE; Fiscal Year: 2013
    ..Using sound experimental and statistical methods and a well characterized patient cohort, the proposed studies are likely to ..
  40. Mechanics of Inner Ear Hair Bundles
    KIRIAKI DOMENICA KARAVITAKI; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): The overall goal is to understand how sound is coupled to individual stereocilia within hair bundles of mammalian cochlea...
  41. Treating cutaneous leishmaniasis by radio-frequency induced heat (RFH) therapy
    Abhay R Satoskar; Fiscal Year: 2012
    ..Accomplishing these aims will lay a sound foundation for our multicenter clinical trial...
  42. Light-Alarming Personal Noise Dosimeter System
    ALEXANDER MILOVANOV; Fiscal Year: 2013
    ..NIOSH is interested in developing personal noise-exposure monitoring system that can immediately alert user when a sound hazard occurs...
  43. The Role of Eya4 in Hearing and Disease
    Jonathan G Seidman; Fiscal Year: 2010
    ..Eya4+/- mice have significant deficiencies in the ability to detect low frequency sound by 22 weeks post birth;ongoing studies will determine if further deterioration of hearing occurs with age...
  44. Partnership for Primary Care Imaging
    Stephen A Boppart; Fiscal Year: 2013
    ..to ultrasound imaging, but generates 3-D images based on the backscatter of near-infrared light rather than sound. This Primary Care Imaging system with a MEMS-based handheld scanner and interchangeable tips enables high-..
  45. Bilateral cochlear implants: Physiology and psychophysics
    Bertrand Delgutte; Fiscal Year: 2012
    ..While wearers of bilateral implants show improved sound localization and speech reception in noise, their ability to process interaural time differences (ITD) is still ..
  46. Developing, Validating, and Implementing a CKD Predictive Model (DELVECKD)
    KHALED A ABDEL-KADER; Fiscal Year: 2013
    ..In summary, the candidate's research interest in improving the quality of CKD care delivery coupled with a sound background in medical education and early training in clinical research make him an ideal candidate to use this ..
  47. Role of the Giant Protein Titin in Skeletal Muscle Structure and Function
    Henk L Granzier; Fiscal Year: 2013
    ..greatly increase the understanding of the role of titin in passive muscle stiffness and that this will provide a sound basis for understanding its role in muscle diseases, which we will address next...
  48. MOLECULAR BASIS OF INHERITED DEAFNESS
    David P Corey; Fiscal Year: 2013
    ..Thus tip links are a key component at the heart of inner ear function-to turn sound and head movement into neural signals...
  49. Akt/mTOR Signaling in Energy Balance Modulation of Epithelial Carcinogenesis
    Stephen D Hursting; Fiscal Year: 2013
    ..between the anticancer effects of CR and the IGF- 1R/Akt/mTOR pathway in epithelial carcinogenesis will provide a sound basis for translational studies to determine if targeting this pathway is a strategy for preventing epithelial ..
  50. Middle-ear Mechanics in Normal and Pathological Ears
    John J Rosowski; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The goal of our work is to understand sound transmission in normal, diseased and reconstructed middle ears so as to develop better diagnostic tests and surgical procedures for patients with middle-..
  51. Molecular mechanisms of auditory nAChR synapse assembly
    Michele H Jacob; Fiscal Year: 2013
    ..and normal exocytotic activity at the afferent presynaptic inputs onto primary auditory neurons that signal sound reception to the brain...
  52. Mechanisms of Sensory Regeneration
    Mark Warchol; Fiscal Year: 2013
    ..Normal sensory function of the inner ear relies on mechanoreceptive hair cells, which convert sound vibrations and head movements into electrical signals that are conveyed to the brain...
  53. Phosphoproteomics of Extinction and Reconsolidation of Drug Memories
    Mary M Torregrossa; Fiscal Year: 2013
    ..While both of these processes sound similar, there is evidence that they actually engage distinct neurobiological processes...
  54. The role of cochlear pericytes in control of cochlear microcirculation
    Xiao Rui Shi; Fiscal Year: 2009
    ..determine the contractile activity of lateral wall pericytes, their physiology and their involvement in the loud sound induced inner ear blood flow alteration...
  55. Occupational exposure to manganese and noise potentiate hearing loss
    Richard J Salvi; Fiscal Year: 2013
    ..following acute treatment, we hypothesize that it has the potential to damage the sensory hair cells that convert sound into neural activity or spiral ganglion neurons (SGN) that transmit acoustic information from the hair cells to ..
  56. Genetic Dissection of Auditory Circuit Assembly
    Lisa V Goodrich; Fiscal Year: 2013
    6. Project Summary/Abstract Hearing begins with the detection of sound by hair cells in the cochlea of the inner ear...
  57. CONTROL OF INNER EAR MICROCIRCULATION
    Alfred L Nuttall; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): A goal of the cochlear physiology laboratory is to understand how sound induced vibration of the tissues in the inner ear results in loss of sensory function and cell pathology...
  58. Stress as a determinant of smoking among sub-populations of Blacks in the U.S.
    Adebola O Odunlami; Fiscal Year: 2011
    ..My career goals are threefold. First, by conducting socially responsible and methodologically sound research, I seek to understand social experiences as determinants of the high cancer prevalence and mortality ..
  59. Defining the role of mast cells during influenza A virus infection
    Joshua J Obar; Fiscal Year: 2012
    ..Additionally, faculty members at both my current and future universities provide a sound network of knowledge which will be invaluable for the successfully completion of the proposed studies...
  60. Roles of K channels in spiral ganglia neurons in health, diseases and aging.
    Ebenezer N Yamoah; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE: Spiral ganglia neurons (SGNs) are the primary neurons that convey sound information in the form of electrical signals from the inner ear to the brain...
  61. Aging Auditory System: Presbycusis and Its Neural Bases
    Robert D Frisina; Fiscal Year: 2013
    ..in sensitivity biased toward the higher frequencies critical for understanding speech, and a serious reduction in sound processing capacity essential for understanding speech in background noise...
  62. Lifestyle Change to Prevent Diabetes via African-American Churches
    RICHARD WARREN SATTIN; Fiscal Year: 2012
    ..Controls will be given currently acceptable and scientifically sound health education programs, derived from the CDC-Community Guide...
  63. Auditory Cortex Plasticity and Tinnitus
    Brian Allman; Fiscal Year: 2012
    ..The efficacy of this treatment approach (sound therapy) has not been evaluated using animals with behavioral evidence of tinnitus...
  64. Gram-Negative Pneumonia and Lipopolysaccharide Binding Protein
    MARK RICHARD HEMMILA; Fiscal Year: 2010
    ..and the co-mentors will maximize the opportunity for the principal investigator to succeed in establishing a sound foundation for a long and successful research career as an independent investigator...
  65. Speech Therapy Robot (STR) to assist in the administration of evidence based spee
    Garima Srivastava; Fiscal Year: 2011
    ..Most children make some mistakes as they learn to say new words, but a speech sound disorder results when mistakes continue past a certain age...
  66. DEVELOPMENT OF SOUND LOCALIZATION
    Catherine Carr; Fiscal Year: 2000
    ..The analysis of temporally ordered inputs is integral to processing both sound location information and communication signals such as speech...
  67. Nighttime Acoustic Pharyngometer (NAP) for Airway Obstruction Identification
    HANI KAYYALI; Fiscal Year: 2009
    ..of acoustic reflectance whereby the distance to an obstruction can be determined from the time it takes a sound wave to travel to that obstruction and back...
  68. ELDER PAIN--ASSESSMENT OF INTENSITY
    Keela Herr; Fiscal Year: 1999
    ..investigation has been conducted on pain assessment and intervention in the non-elderly, efforts to provide a sound scientific base for the elderly have been limited...
  69. BIOMECHANICS OF THE MIDDLE EAR
    THOMAS HETHERINGTON; Fiscal Year: 1990
    ..The opercularis system also appears to function in sound reception...
  70. Wide-bandwidth open canal hearing aid for better multitalker speech understanding
    Sunil Puria; Fiscal Year: 2009
    ..The most frequently cited complaints include difficulty understanding speech in multi-talker situations, poor sound quality, dislike of the sound of their amplified voice, and unwanted whistling sounds caused by acoustic feedback...