photochemistry

Summary

Top Publications

  1. ncbi Photobleaching and photoactivation: following protein dynamics in living cells
    Jennifer Lippincott-Schwartz
    Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Cell Biol . 2003
  2. doi Adhesion and migration of ovarian cancer cells on crosslinked laminin fibers nanofabricated by multiphoton excited photochemistry
    Xiyi Chen
    Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030, USA
    Integr Biol (Camb) 1:469-76. 2009
  3. ncbi Photochemistry of organic iron(III) complexing ligands in oceanic systems
    Katherine Barbeau
    Geosciences Research Division, Scripps Institution of Oceanography, University of California, San Diego, San Diego, CA, USA
    Photochem Photobiol 82:1505-16. 2006
  4. doi Recent developments in photocatalytic water treatment technology: a review
    Meng Nan Chong
    School of Chemical Engineering, The University of Adelaide, 5005 Adelaide, Australia
    Water Res 44:2997-3027. 2010
  5. ncbi The bactericidal effect of TiO2 photocatalysis involves adsorption onto catalyst and the loss of membrane integrity
    Gaëtan Gogniat
    ENAC Laboratory for Environmental Biotechnology, Swiss Federal Institute of Technology EPFL, Lausanne, Switzerland
    FEMS Microbiol Lett 258:18-24. 2006
  6. ncbi The retinal pigment epithelium in visual function
    Olaf Strauss
    Bereich Experimentelle Ophthalmologie, Klinik und Poliklinik fuer Augenheilkunde, Universitaetsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Physiol Rev 85:845-81. 2005
  7. pmc Whole-cell response of the pennate diatom Phaeodactylum tricornutum to iron starvation
    Andrew E Allen
    Centre National de la Recherche Scientifique Unite Mixte de Recherche 8186, Dept of Biology, Ecole Normale Superieure, 46 rue d Ulm, 75005 Paris, France
    Proc Natl Acad Sci U S A 105:10438-43. 2008
  8. doi Photoproduction of catalase-insensitive peroxides on the donor side of manganese-depleted photosystem II: evidence with a specific fluorescent probe
    Sergey A Khorobrykh
    Institute of Basic Biological Problems, Russian Academy of Sciences, Pushchino, Moscow Region 142290, Russia
    Biochemistry 50:10658-65. 2011
  9. ncbi Engineering of a monomeric green-to-red photoactivatable fluorescent protein induced by blue light
    Nadya G Gurskaya
    Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho Maklaya 16 10, Moscow 117997, Russia
    Nat Biotechnol 24:461-5. 2006
  10. doi Excited state reactions in fluorescent proteins
    Stephen R Meech
    School of Chemistry, University of East Anglia, Norwich, UK NR1 2QN
    Chem Soc Rev 38:2922-34. 2009

Research Grants

  1. PHOTOSENSTIZATION MECHANISMS IN HYPOXIC MEDIA
    ROBERT REDMOND; Fiscal Year: 2003
  2. HEME PROTEINS, MICROSPHERES, AND SYNTHETIC ANALOGS
    KENNETH SUSLICK; Fiscal Year: 2000
  3. Bilirubin and Photobilirubin: Metabolism & Exretion
    Antony McDonagh; Fiscal Year: 2005
  4. Electron Transfer in Iron and Copper Proteins
    Jay R Winkler; Fiscal Year: 2010
  5. HEME PROTEINS AND THEIR SYNTHETIC ANALOGS
    KENNETH SUSLICK; Fiscal Year: 1993
  6. ULTRAVIOLET LIGHT INDUCED PHENOMENA IN BIOMEMBRANES
    IRENE KOCHEVAR; Fiscal Year: 1999
  7. THE PHOTOBIOLOGY OF VITAMIN D3
    Michael Holick; Fiscal Year: 1993
  8. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    KENNETH KARLIN; Fiscal Year: 2007
  9. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    KENNETH KARLIN; Fiscal Year: 2009
  10. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    KENNETH KARLIN; Fiscal Year: 2009

Detail Information

Publications344 found, 100 shown here

  1. ncbi Photobleaching and photoactivation: following protein dynamics in living cells
    Jennifer Lippincott-Schwartz
    Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Cell Biol . 2003
    ..Widespread applications of these fluorescent-based methods are revealing new aspects of protein dynamics and the biological processes that they regulate...
  2. doi Adhesion and migration of ovarian cancer cells on crosslinked laminin fibers nanofabricated by multiphoton excited photochemistry
    Xiyi Chen
    Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030, USA
    Integr Biol (Camb) 1:469-76. 2009
    ..To explore this possibility, we have used multiphoton excited photochemistry (MPE) to synthesize models of the ovarian basal lamina consisting of crosslinked laminin nanofibers to ..
  3. ncbi Photochemistry of organic iron(III) complexing ligands in oceanic systems
    Katherine Barbeau
    Geosciences Research Division, Scripps Institution of Oceanography, University of California, San Diego, San Diego, CA, USA
    Photochem Photobiol 82:1505-16. 2006
    ..This review highlights recent findings, including both model ligand studies and experimentallobservational studies of the natural seawater ligand pool...
  4. doi Recent developments in photocatalytic water treatment technology: a review
    Meng Nan Chong
    School of Chemical Engineering, The University of Adelaide, 5005 Adelaide, Australia
    Water Res 44:2997-3027. 2010
    ..This paper will deliver a scientific and technical overview and useful information to scientists and engineers who work in this field...
  5. ncbi The bactericidal effect of TiO2 photocatalysis involves adsorption onto catalyst and the loss of membrane integrity
    Gaëtan Gogniat
    ENAC Laboratory for Environmental Biotechnology, Swiss Federal Institute of Technology EPFL, Lausanne, Switzerland
    FEMS Microbiol Lett 258:18-24. 2006
    ..Our work suggests that adsorption of cells onto aggregated TiO2, followed by loss of membrane integrity, is key to the bactericidal effect of photocatalysis...
  6. ncbi The retinal pigment epithelium in visual function
    Olaf Strauss
    Bereich Experimentelle Ophthalmologie, Klinik und Poliklinik fuer Augenheilkunde, Universitaetsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Physiol Rev 85:845-81. 2005
    ..On the other hand, mutations in genes expressed in photoreceptors can lead to degenerations of the RPE. Thus both tissues can be regarded as a functional unit where both interacting partners depend on each other...
  7. pmc Whole-cell response of the pennate diatom Phaeodactylum tricornutum to iron starvation
    Andrew E Allen
    Centre National de la Recherche Scientifique Unite Mixte de Recherche 8186, Dept of Biology, Ecole Normale Superieure, 46 rue d Ulm, 75005 Paris, France
    Proc Natl Acad Sci U S A 105:10438-43. 2008
    ..Iron limitation leads to the elevated expression of at least three gene clusters absent from the Thalassiosira pseudonana genome that encode for components of iron capture and uptake mechanisms...
  8. doi Photoproduction of catalase-insensitive peroxides on the donor side of manganese-depleted photosystem II: evidence with a specific fluorescent probe
    Sergey A Khorobrykh
    Institute of Basic Biological Problems, Russian Academy of Sciences, Pushchino, Moscow Region 142290, Russia
    Biochemistry 50:10658-65. 2011
    ..These ROOH forms, likely including several species derived from lipid peroxides, may mediate the donor side-induced photoinhibition of PSII via protein modification...
  9. ncbi Engineering of a monomeric green-to-red photoactivatable fluorescent protein induced by blue light
    Nadya G Gurskaya
    Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho Maklaya 16 10, Moscow 117997, Russia
    Nat Biotechnol 24:461-5. 2006
    ..We demonstrate the suitability of Dendra for protein labeling and tracking to quantitatively study dynamics of fibrillarin and vimentin in mammalian cells...
  10. doi Excited state reactions in fluorescent proteins
    Stephen R Meech
    School of Chemistry, University of East Anglia, Norwich, UK NR1 2QN
    Chem Soc Rev 38:2922-34. 2009
    ..Finally the photophysics underlying the new generation of photochemically active fluorescent proteins are discussed (155 references)...
  11. ncbi Too much light? How beta-carotene protects the photosystem II reaction centre
    Alison Telfer
    Division of Molecular Biosciences, Imperial College London, South Kensington Campus, London, UK SW7 2AZ
    Photochem Photobiol Sci 4:950-6. 2005
    ..The relevance of a cycle of electrons around photosystem II, via cytochrome b(559), in order to re-reduce the beta-carotenes when they are oxidised and hence restore their ability to quench singlet oxygen, is also discussed...
  12. ncbi Factors affecting virus photoinactivation by a series of phenothiazine dyes
    S J Wagner
    American Red Cross Biomedical Services, Jerome H Holland Laboratory for the Biomedical Sciences, Rockville, MD 20855, USA
    Photochem Photobiol 67:343-9. 1998
    ....
  13. ncbi Making light work of enzyme catalysis: protochlorophyllide oxidoreductase
    Derren J Heyes
    Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, UK
    Trends Biochem Sci 30:642-9. 2005
    ..Recent advances in our understanding of the catalytic mechanism of POR illustrate why it is an important generic model for studying enzyme catalysis and reaction dynamics...
  14. ncbi Remote energy storage in Ni(OH)2 with TiO2 photocatalyst
    Yukina Takahashi
    Institute of Industrial Science, University of Tokyo, Komaba, Tokyo, 153 8505, Japan
    Phys Chem Chem Phys 8:2716-9. 2006
    ..It was revealed that the stored energy could be taken out and used chemically or electrochemically. The oxidized Ni(OH)2 was reduced by gaseous formaldehyde, formate, ethanol and H2O2...
  15. ncbi Photoelectric properties of a detector based on dried bacteriorhodopsin film
    Wei Wei Wang
    Department of Mechanical and Materials Engineering, Faculty of Engineering, The University of Western Ontario, London, Ontario, Canada N6A 5B9
    Biosens Bioelectron 21:1309-19. 2006
    ..Experimental observations and a predictive model both support the notion that dried bR film can be used in simple highly sensitive photo-detector designs...
  16. pmc Enzymology below 200 K: the kinetics and thermodynamics of the photochemistry catalyzed by protochlorophyllide oxidoreductase
    Derren J Heyes
    Robert Hill Institute for Photosynthesis and Krebs Institute for Biomolecular Research, Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, United Kingdom
    Proc Natl Acad Sci U S A 99:11145-50. 2002
    ....
  17. pmc Environmental carcinogenic polycyclic aromatic hydrocarbons: photochemistry and phototoxicity
    Hongtao Yu
    Department of Chemistry, Jackson State University, Jackson, MS 39217, USA
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 20:149-83. 2002
    ..Although many books and reviews on these subjects have been published, PAH photochemistry and phototoxicity have received much less attention...
  18. ncbi Functional recovery and expression of GDNF seen in photochemically induced cerebral infarction
    Keisuke Horinouchi
    Department of Rehabilitation and Physical Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan
    Int J Neurosci 117:315-26. 2007
    ..Therefore, the expression of GDNF protein might have some relationship with the functional recovery of paralysis. There are great hopes that GDNF could be used as a therapeutic agent for cerebral infarction...
  19. ncbi Binding, aggregation and photochemical properties of methylene blue in mitochondrial suspensions
    Dino Gabrielli
    Departamento de Bioquimica, Instituto de Quimica, Universidade de Sao Paulo, Sao Paulo, Brazil
    Photochem Photobiol 79:227-32. 2004
    ..These differences in photochemical properties should influence the cytotoxic effects of photodynamic treatment in the presence of MB...
  20. ncbi Phytochrome-interacting factor 1 is a critical bHLH regulator of chlorophyll biosynthesis
    Enamul Huq
    Section of Molecular Cell and Developmental Biology and Institute of Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA
    Science 305:1937-41. 2004
    ....
  21. ncbi Photochemical products in urban mixtures enhance inflammatory responses in lung cells
    Kenneth G Sexton
    Department of Environmental Science and Engineering, University of North Carolina at Chapel Hill, 27599, USA
    Inhal Toxicol 16:107-14. 2004
    ..In the absence of such particles, these gaseous products remained mostly as gases. These experiments show that photochemically produced gaseous products do influence the toxic responses of the cells in the absence of particles...
  22. ncbi Caged compounds: photorelease technology for control of cellular chemistry and physiology
    Graham C R Ellis-Davies
    Department of Pharmacology and Physiology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, USA
    Nat Methods 4:619-28. 2007
    ..Here I describe important examples of widely used caged compounds, their design features and synthesis, as well as practical details of how to use them with living cells...
  23. ncbi Determination of two phototransformation products of bentazone using quadrupole time-of-flight mass spectrometry
    Manuela Peschka
    Europa University of Applied Sciences, Limburger Strasse 2, Idstein, Germany
    Anal Bioanal Chem 388:1227-34. 2007
    ..The required irradiation time was matrix dependent. 2-(Isopropylcarbamoyl)phenylsulfamic acid was detected in a drainage channel in the Ebro river delta (Catalonia, Spain)...
  24. doi Reactive oxygen species in photochemistry of the red fluorescent protein "Killer Red"
    Russell B Vegh
    School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332 0400, USA
    Chem Commun (Camb) 47:4887-9. 2011
    ..We have investigated the source of the bioactive species through a variety of photophysical and photochemical techniques. Our results indicate a Type I (electron transfer mediated) photosensitizing mechanism...
  25. pmc Different inactivation behaviors of MS-2 phage and Escherichia coli in TiO2 photocatalytic disinfection
    Min Cho
    School of Chemical Engineering, College of Engineering, Seoul National University, Sillim dong, Gwanak Gu, Seoul 151 742, South Korea
    Appl Environ Microbiol 71:270-5. 2005
    ..coli is inactivated by both the free and the surface-bound hydroxyl radicals. E. coli might also be inactivated by other ROS, such as O(2).(-) and H(2)O(2), according to the present results...
  26. doi Quantum-dot-sensitized TiO2 inverse opals for photoelectrochemical hydrogen generation
    Chuanwei Cheng
    Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, 637371 Singapore, Singapore
    Small 8:37-42. 2012
    ..The photoelectrochemical performance shows high photocurrent density (4.84 mA cm(-2) at 0 V vs. Ag/AgCl) under simulated solar-light illumination...
  27. ncbi Formation of radicals from singlet oxygen produced during photoinhibition of isolated light-harvesting proteins of photosystem II
    Sara Rinalducci
    Department of Environmental Sciences, University of Tuscia, Largo dell Universita, 01100 Viterbo, Italy
    Biochim Biophys Acta 1608:63-73. 2004
    ..Thus, monomerization of antennae as well as their incorporation into the PSII complex seem to represent physiologically protected forms. A comparison is made of the photoinhibition mechanisms of different photosynthetic systems...
  28. doi Photochemistry of norharmane in aqueous solution
    M Micaela Gonzalez
    CIHIDECAR CONICET, Departamento de Quimica Organica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellon 2, 3p, Ciudad Universitaria, 1428, Buenos Aires, Argentina
    Photochem Photobiol Sci 8:1139-49. 2009
    The photochemistry of norharmane (9H-pyrido[3,4-b]indole) in acidic (pH 5.0+/-0.1) and alkaline (pH 10.0+/-0.1) aqueous solutions was studied...
  29. ncbi Photodynamic therapy: update 2006. Part 1: Photochemistry and photobiology
    P G Calzavara-Pinton
    Department of Dermatology, Azienda Ospedaliera Spedali Civili and University of Brescia, Piazzale Spedali Civili 1, 25123 Brescia, Italy
    J Eur Acad Dermatol Venereol 21:293-302. 2007
    ..This paper provides an overview of the chemistry of the photosensitizers, the photobiology and photoimmunology of the photodynamic reaction as well as the photophysical characteristics of the light sources available for PDT...
  30. ncbi Photophysics and photochemistry of z-chlorprothixene in acetonitrile
    Luis E Piñero
    Department of Chemistry, University of Puerto Rico at Humacao, Humacao, Puerto Rico
    Photochem Photobiol 85:895-900. 2009
    ..These results indicate that the phototoxicity of zCPTX is somehow affected by the formation of CTX...
  31. doi Photochemistry in photonic crystal fiber nanoreactors
    Jocelyn S Y Chen
    Max Planck Institut für die Physik des Lichts, Günther Scharowsky Strasse 1 Bau 24, 91058 Erlangen, Germany
    Chemistry 16:5607-12. 2010
    ..Furthermore, the enhanced sensitivity and optical pump intensity implied that even systems with very small quantum yields can be measured very quickly--in our experiments one thousand times faster than in a conventional cuvette...
  32. doi Synthesis and DNA interactions of a bis-phenothiazinium photosensitizer
    Beth Wilson
    Department of Chemistry, Georgia State University, P O Box 4098, Atlanta, GA 30302 4098, USA
    Org Biomol Chem 6:4026-35. 2008
    ..Finally, viscometric data indicated that CT DNA interacts with compound 3 and MB by a combination of groove binding and monofunctional intercalation, and with compound 3 by a third, bisintercalative binding mode...
  33. doi Virus inactivation by silver doped titanium dioxide nanoparticles for drinking water treatment
    Michael V Liga
    Department of Civil and Environmental Engineering, Rice University, Houston, TX 77005, USA
    Water Res 45:535-44. 2011
    ..The increased production of hydroxyl free radicals was found to be responsible for the enhanced viral inactivation...
  34. doi The photochemistry of fluorescent proteins: implications for their biological applications
    Harriet E Seward
    Department of Biochemistry, University of Leicester, Henry Wellcome Building, Lancaster Road, Leicester, UK LE1 9HN
    Chem Soc Rev 38:2842-51. 2009
    ..In this tutorial review, we discuss the photochemistry of this fascinating class of proteins and illustrate some of their advantages and drawbacks in a range of ..
  35. doi One- and two-photon excitation of beta-carbolines in aqueous solution: pH-dependent spectroscopy, photochemistry, and photophysics
    M Micaela Gonzalez
    CIHIDECAR CONICET, Departamento de Quimica Organica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, 1428 Buenos Aires, Argentina
    J Phys Chem A 113:6648-56. 2009
    ..In this work, a study of the aqueous solution-phase photochemistry, photophysics, and spectroscopy of three important betaCs [norharmane (nHo), harmane (Ho), and harmine (Ha)] ..
  36. doi The role of reactive oxygen species in Staphylococcus aureus photoinactivation by methylene blue
    Sonia Sabbahi
    National Institute of Research of Rural Engineering Water and Forestry Tunis, rue Hédi Karray, B P 10, 2080, Ariana, Tunis, Tunisia
    Water Sci Technol 58:1047-54. 2008
    ..aureus were studied spectrophotometrically. This demonstrated that a metachromatic reaction took place between MB and S. aureus bacteria. Furthermore, S. aureus bacteria induced additional dimerization of MB...
  37. doi Rational design of photoconvertible and biphotochromic fluorescent proteins for advanced microscopy applications
    Virgile Adam
    Laboratory of Photochemistry and Spectroscopy, Department of Chemistry, Katholieke Universiteit Leuven, 3001 Heverlee, Belgium
    Chem Biol 18:1241-51. 2011
    ..We present in particular NijiFP, a promising new fluorescent protein with photoconvertible and biphotochromic properties that make it ideal for advanced fluorescence-based imaging applications...
  38. ncbi Surface photochemistry of pesticides: an approach using diffuse reflectance and chromatography techniques
    José P Da Silva
    Centro de Quimica Fisica Molecular, Instituto Superior Tecnico, 1049 001 Lisboa, Portugal
    Environ Sci Technol 38:2849-56. 2004
    The photochemistry of pesticides triadimenol and triadimefon was studied on cellulose and beta-cyclodextrin (beta-CD) in controlled and natural conditions, using diffuse reflectance techniques and chromatographic analysis...
  39. doi Environmental photochemistry of nitro-PAHs: direct observation of ultrafast intersystem crossing in 1-nitropyrene
    Carlos E Crespo-Hernandez
    Department of Chemistry, Center for Chemical Dynamics, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA
    J Phys Chem A 112:6313-9. 2008
    ..The small energy gap suggests a large spin-orbit coupling between the S1(pipi*) and T3(npi*) states, which explains the ultrafast intersystem crossing of 1-nitropyrene in nonpolar solvents...
  40. pmc Characterization and photochemistry of 13-desmethyl bacteriorhodopsin
    Nathan B Gillespie
    Department of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, Connecticut 06269 3060, USA
    J Phys Chem B 109:16142-52. 2005
    The photochemistry of the 13-desmethyl (DM) analogue of bacteriorhodopsin (BR) is examined by using spectroscopy, molecular orbital theory, and chromophore extraction followed by conformational analysis...
  41. pmc Site-specific solvation of the photoexcited protochlorophyllide a in methanol: formation of the hydrogen-bonded intermediate state induced by hydrogen-bond strengthening
    Guang Jiu Zhao
    State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, Liaoning, China
    Biophys J 94:38-46. 2008
    ....
  42. doi Protochlorophyllide a: A Comprehensive Photophysical Picture
    Benjamin Dietzek
    Institute for Physical Chemistry, University Jena, Lessingstrasse 10, 07743 Jena, Germany
    Chemphyschem 10:144-50. 2009
    The photochemistry of protochlorophyllide a, a precursor in the biosynthesis of chlorophyll and substrate of the light regulated enzyme protochlorophyllide oxidoreductase, is investigated by pump-probe spectroscopy...
  43. ncbi UV photochemistry of DNA in vitro and in Bacillus subtilis spores at earth-ambient and low atmospheric pressure: implications for spore survival on other planets or moons in the solar system
    Wayne L Nicholson
    Department of Veterinary Science and Microbiology, University of Arizona, Tucson, Arizona 85721, USA
    Astrobiology 2:417-25. 2002
    ..To date, however, spore survival and DNA photochemistry have been explored only at the extremes of Earth-normal atmospheric pressure (101...
  44. doi Nuclear quantum tunneling in the light-activated enzyme protochlorophyllide oxidoreductase
    Derren J Heyes
    Manchester Interdisciplinary Biocentre, Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN, United Kingdom
    J Biol Chem 284:3762-7. 2009
    ..Consequently, we have established the first important link between photochemical and nuclear quantum tunneling reactions, linked to protein dynamics, in a biologically significant system...
  45. doi Photocontrol of single-chain DNA conformation in cell-mimicking microcompartments
    Matthieu Sollogoub
    Institut de Chimie Moléculaire FR2769, Laboratoire de Chimie Organique UMR CNRS 7611, UPMC Universite Paris 06, 75005 Paris, France
    Chembiochem 9:1201-6. 2008
  46. doi Vibrioferrin, an unusual marine siderophore: iron binding, photochemistry, and biological implications
    Shady A Amin
    Department of Chemistry and Biochemistry, San Diego State University, San Diego, California 92182 1030, USA
    Inorg Chem 48:11451-8. 2009
    ..The consequences that these features have on bacterial-algal interactions with potential importance to understanding the origin and sustenance of harmful algal blooms are discussed...
  47. ncbi Surface photochemistry: organic molecules within nanocavities of calixarenes
    Luis F Vieira Ferreira
    Centro de Química Física Molecular Complexo I, Inst Sup Téc, Universidade Tecnica de Lisboa, Av Rovisco Pais 1049 001 Lisboa, Portugal
    Curr Drug Discov Technol 4:229-45. 2007
    ..One of the main conclusions was that the solid support can deeply affect or even control the photochemistry of an adsorbed probe...
  48. doi Prebiotic significance of extraterrestrial ice photochemistry: detection of hydantoin in organic residues
    Pierre de Marcellus
    Universite Paris Sud, Astrochimie et Origines, Institut d Astrophysique Spatiale, Orsay, France
    Astrobiology 11:847-54. 2011
    ..result, together with other related experiments reported recently, points to the potential importance of the photochemistry of interstellar "dirty" ices in the formation of organics in Solar System materials...
  49. doi Electric field quenching of carbon nanotube photoluminescence
    Anton V Naumov
    Applied Physics Program, Rice University, Houston, Texas 77005, USA
    Nano Lett 8:1527-31. 2008
    ..Photoluminescence intensity was found to follow a reciprocal hyperbolic cosine dependence on electric field...
  50. ncbi Effect of light on self-assembly of aqueous mixtures of sodium dodecyl sulfate and a cationic, bolaform surfactant containing azobenzene
    F Pierce Hubbard
    Department of Chemical and Biological Engineering, University of Madison Wisconsin, 1415 Engineering Drive, Madison, Wisconsin 53706 1691, USA
    Langmuir 23:4819-29. 2007
    ..g., vesicles rich in trans-BTHA and SDS coexist with micelles rich in cis-BTHA and SDS). The results presented in this paper provide guidance for the design of light-tunable surfactants systems...
  51. doi Morphological changes in vesicles and release of an encapsulated compound triggered by a photoresponsive Malachite Green leuconitrile derivative
    Ryoko M Uda
    Department of Chemical Engineering, Nara National College of Technology, Yata 22, Yamato koriyama, Nara 639 1080, Japan
    Langmuir 26:5444-50. 2010
    ..Furthermore, irradiation of the Malachite Green derivative induces the release of a vesicle-encapsulated compound...
  52. doi Photochemistry, remotely sensed physiological reflectance index and de-epoxidation state of the xanthophyll cycle in Quercus coccifera under intense drought
    José Javier Peguero-Pina
    Unidad de Recursos Forestales, Centro de Investigación y Tecnología Agroalimentaria, Gobierno de Aragón, Apdo 727, 50080 Saragossa, Spain
    Oecologia 156:1-11. 2008
    ..It is concluded that, contrary to early reports, PRI is a sensible, indirect, non-destructive water stress indicator, even in plants experiencing intense drought...
  53. pmc EosFP, a fluorescent marker protein with UV-inducible green-to-red fluorescence conversion
    Jörg Wiedenmann
    Department of General Zoology and Endocrinology, University of Ulm, 89069 Ulm, Germany
    Proc Natl Acad Sci U S A 101:15905-10. 2004
    ..The possibility to locally change the emission wavelength by focused UV light makes EosFP a superb marker for experiments aimed at tracking the movements of biomolecules within the living cell...
  54. pmc Comparative photochemistry of animal type 1 and type 4 cryptochromes
    Nuri Ozturk
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    Biochemistry 48:8585-93. 2009
    ..Although the photochemistry of plant CRYs has been studied in some detail, the photochemical behavior of animal cryptochromes remains ..
  55. ncbi Effect of denaturation on the photochemistry of pyrimidine bases in isolated DNA
    Thierry Douki
    Laboratoire Lesions des Acides Nucleiques, Service de Chimie Inorganique et Biologique UMR E 3 CEA UJF, CEA DSM Département de Recherche Fondamentale sur la Matière Condensée, CEA Grenoble, 38054 Grenoble Cedex 9, France
    J Photochem Photobiol B 82:45-52. 2006
    The influence of denaturation on DNA photochemistry was studied by quantifying the yield of formation of all possible bipyrimidine photolesions within isolated genomic DNA samples exposed to UVC radiation...
  56. ncbi Identification and characterization of the product release steps within the catalytic cycle of protochlorophyllide oxidoreductase
    Derren J Heyes
    Robert Hill Institute for Photosynthesis, Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, United Kingdom
    Biochemistry 43:8265-71. 2004
    ..Following release of Chlide, the subsequent binding of Pchlide allows the next catalytic cycle to proceed...
  57. ncbi Prebiotic adenine revisited: eutectics and photochemistry
    Leslie E Orgel
    The Salk Institute for Biological Studies, San Diego, CA, USA
    Orig Life Evol Biosph 34:361-9. 2004
    ..It is further suggested that the reaction of cyanoacetylene with cyanate in eutectic solution to give cytosine might have proceeded in parallel with adenine synthesis...
  58. ncbi The excited-state chemistry of protochlorophyllide a: a time-resolved fluorescence study
    Benjamin Dietzek
    Institut fur Physikalische Chemie, Bayerische Julius Maximilians Universität Würzburg, Am Hubland, 97074 Wurzburg, Germany
    Chemphyschem 7:1727-33. 2006
    ....
  59. ncbi Structural events in the photocycle of green fluorescent protein
    Jasper J van Thor
    Laboratory of Molecular Biophysics, University of Oxford, Rex Richards Building, South Parks Road, Oxford OX1 3QU, United Kingdom
    J Phys Chem B 109:16099-108. 2005
    ..Vibrational spectral markers at 1695 cm(-1) assigned to Gln 69, at 1631 cm(-1) belonging to a C=C mode, and at 1354 cm(-1) belonging to a phenolate vibration further indicated the I2 and I* states to be unrelaxed...
  60. ncbi Photocatalytic degradation of E. coliform in water
    Darren Delai Sun
    Environmental Engineering Research Center, School of Civil and Environmental Engineering, Nanyang Technological University, 639798 Singapore
    Water Res 37:3452-62. 2003
    ....
  61. ncbi Visible light inactivation of bacteria and fungi by modified titanium dioxide
    Dariusz Mitoraj
    Faculty of Chemistry, Jagiellonian University, ul Ingardena 3, 30 060 Krakow, Poland
    Photochem Photobiol Sci 6:642-8. 2007
    ..faecalis>>C. albicans approximately A. niger. This sequence results most probably from differences in cell wall or cell membrane structures in these microorganisms and is not related to the ability of catalase production...
  62. ncbi Binding and photochemistry of enantiomeric 2-(3-benzoylphenyl)propionic acid (ketoprofen) in the human serum albumin environment
    Sandra Monti
    Istituto per la Sintesi Organica e la Fotoreattivita ISOF, CNR, Via P Gobetti 101, 40129, Bologna, Italy
    Photochem Photobiol Sci 6:462-70. 2007
    ..7-0.9). Secondary transients were consistent with the occurrence of photodecarboxylation and/or photoreduction within the protein matrix...
  63. ncbi Production of reactive oxygen species in chloride- and calcium-depleted photosystem II and their involvement in photoinhibition
    Andras Arato
    Institut fur Biologie II, Biochemie der Pflanzen, Universitat Freiburg, Schänzlestr 1, 79104 Freiburg, Germany
    Biochim Biophys Acta 1608:171-80. 2004
    ....
  64. ncbi Photochemistry of 5-S-cysteinyldopa
    C Costantini
    Department of Organic and Biological Chemistry, University of Naples, Italy
    Photochem Photobiol 60:33-7. 1994
    ..These results are of interest in relation to the high susceptibility of fair-complexioned individuals to actinic damage and skin cancer...
  65. ncbi Ultrafast time-resolved transient absorption and resonance raman spectroscopy study of the photodeprotection and rearrangement reactions of p-hydroxyphenacyl caged phosphates
    Chensheng Ma
    Contribution from the Department of Chemistry, The University of Hong Kong, SAR, P R China
    J Am Chem Soc 128:2558-70. 2006
    ..J. Am. Chem. Soc. 2005, 127, 1463-1472) provide a real time overall mechanistic description for the photodeprotection and rearrangement reactions of pHP caged phosphate phototrigger compounds...
  66. ncbi Photoconsumption of oxygen in photosystem II preparations under impairment of the water-oxidizing complex
    S A Khorobrykh
    Institute of Basic Biological Problems, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia
    Biochemistry (Mosc) 67:683-8. 2002
    ....
  67. ncbi Transient absorption and photovoltage study of' self-assembled bacteriorhodopsin/polycation multilayer films
    Tapio Jussila
    Institute of Materials Chemistry, Tampere University of Technology, PO Box 541, 33101, Tampere, Finland
    Biosens Bioelectron 17:509-15. 2002
    ..A simultaneous two-exponential decay in millisecond time domain was observed at red wavelengths. The source of the red-shifted absorption is suggested to be the C(610) intermediate of the cis photocycle of bR...
  68. pmc The effects of the bacterial interaction with visible-light responsive titania photocatalyst on the bactericidal performance
    Chia Liang Cheng
    Department of Physics, National Dong Hwa University, Hualien, Taiwan
    J Biomed Sci 16:7. 2009
    ..These findings suggest the created materials with high bacterial interaction ability might be a useful strategy to improve the antimicrobial activity of visible-light-activated TiO2...
  69. ncbi H-aggregation of azobenzene-substituted amphiphiles in vesicular membranes
    Johanna M Kuiper
    Stratingh Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands
    Langmuir 20:1152-60. 2004
    ....
  70. ncbi Reversible photoswitching in a cell-sized vesicle
    Tsutomu Hamada
    Department of Physics, Graduate School of Science, Kyoto University, Kyoto 606 8502, Japan
    Langmuir 21:7626-8. 2005
    ..The mechanism of this reversible photoswitching in the vesicle morphology is interpreted in terms of a change in the effective cross-sectional area of the photosensitive molecule...
  71. ncbi Controlling photochemistry with distinct hydrophobic nanoenvironments
    Lakshmi S Kaanumalle
    Department of Chemistry, Tulane University, New Orleans, Louisiana 70118, USA
    J Am Chem Soc 126:14366-7. 2004
    ..Encapsulated guests such as dibenzyl ketones reside in an essentially dry environment, and upon irradiation, undergo rearrangement processes that are templated by the shape of the 1 nm x 2 nm cavity...
  72. pmc Production and scavenging of reactive oxygen species in chloroplasts and their functions
    Kozi Asada
    Faculty of Life Science and Biotechnology, Fukuyama University, Fukuyama 729 0292, Japan
    Plant Physiol 141:391-6. 2006
  73. ncbi Radiometric quantities and units used in photobiology and photochemistry: recommendations of the Commission Internationale de L'Eclairage (International Commission on Illumination)
    David H Sliney
    International Commission on Illumination CIE, Vienna, Austria
    Photochem Photobiol 83:425-32. 2007
    ..As photobiology and photochemistry both represent the fusion of several scientific disciplines, it is not surprising that the physical terms used ..
  74. ncbi Heterogeneous photocatalyzed degradation of uracil and 5-bromouracil in aqueous suspensions of titanium dioxide
    H K Singh
    Department of Chemistry, Aligarh Muslim University, Aligarh 202002, India
    J Hazard Mater 142:425-30. 2007
    ..Photocatalyst Degussa P25 was found to be more efficient for the degradation of both compounds as compared with other TiO2 powders such as UV100, PC500 and TTP...
  75. ncbi Kinetic study on photocatalytic degradation of C.I. Acid Yellow 23 by ZnO photocatalyst
    M A Behnajady
    Department of Applied Chemistry, Islamic Azad University, Tabriz, Islamic Republic of Iran
    J Hazard Mater 133:226-32. 2006
    ..A comparison between experimental and calculated apparent reaction rate constants shows that the results obtained from the L-H modified model are in good agreement with experimental data...
  76. ncbi Photocatalytic activity for degradation of nitrogen oxides over visible light responsive titania-based photocatalysts
    Yu Ming Lin
    Center for Environmental, Safety and Health Technology Development, Industrial Technology Research Institute, Room 204, Building 32, 195, Section 4, Chung Hsing Road, Chutung, Hsinchu 310, Taiwan
    Environ Sci Technol 40:1616-21. 2006
    ..Rinsing with water was responsible for the restored reactivity of prepared TiO2 catalysts for NO(x) degradation...
  77. ncbi Crystallographic analysis of primary visual photochemistry
    Hitoshi Nakamichi
    Biological Information Research Center, National Institute of Advanced Industrial Science and Technology, 2 41 6 Aomi, Koto ku, Tokyo 135 0064, Japan
    Angew Chem Int Ed Engl 45:4270-3. 2006
  78. ncbi Synthesis and photochemistry of a two-position Ru(terpy)(phen)(L)2+ scorpionate complex
    Sylvestre Bonnet
    Laboratoire de Chimie Organo Minerale, UMR 7513 du CNRS, Institut Le Bel, Universite Louis Pasteur, 4 rue Blaise Pascal, 67000 Strasbourg Cedex, France
    Inorg Chem 45:4024-34. 2006
    ..Thermal back-coordination of the tail was investigated in the dark. It took place quantitatively from the corresponding ruthenium chloride complex by trapping of the anion with silver salts...
  79. ncbi Photoreversible DNA condensation using light-responsive surfactants
    Anne Laure M Le Ny
    Department of Chemical Engineering and Material Sciences, University of Southern California, Los Angeles, California 90089 1211, USA
    J Am Chem Soc 128:6400-8. 2006
    ..The combined results clearly show the ability to control the interaction between DNA and the complexing agent and, therefore, DNA condensation with light...
  80. ncbi Gas-phase photochemistry of the photoactive yellow protein chromophore trans-p-coumaric acid
    Wendy L Ryan
    Department of Chemistry, University of Chicago, Chicago, Illinois 60637, USA
    J Am Chem Soc 124:6194-201. 2002
    ..Although trans-CA was excited in all three regions, a significant cis-CA peak appeared only in region II, though a small cis peak was observed in region III...
  81. ncbi Ultrafast photoisomerization of photoactive yellow protein chromophore analogues in solution: influence of the protonation state
    Agathe Espagne
    UMR CNRS ENS 8640 PASTEUR, Departement de Chimie, Ecole Normale Superieure, 24 rue Lhomond, 75231 Paris Cedex 05, France
    Chemphyschem 7:1717-26. 2006
    ..A trans-to-cis isomerization mechanism involving mainly the ethylenic double-bond torsion and/or solvation is proposed for the anionic forms, whereas "concerted" intramolecular motions are proposed for the neutral forms...
  82. pmc Structural evolution of the chromophore in the primary stages of trans/cis isomerization in photoactive yellow protein
    Karsten Heyne
    Max Born Institut fur Nichtlineare Optik und Kurzzeitspektroskopie, Max Born Strasse 2A, D 12489 Berlin, Germany
    J Am Chem Soc 127:18100-6. 2005
    ....
  83. ncbi Solvent effect on the excited-state dynamics of analogues of the photoactive yellow protein chromophore
    Agathe Espagne
    Departement de Chimie, Ecole Normale Superieure UMR CNRS 8640 PASTEUR, 24 rue Lhomond, 75231 Paris Cedex 05, France
    J Phys Chem A 110:3393-404. 2006
    ..The excited-state deactivation of pCT- would lead to the formation of a ground-state intermediate at the "perp" geometry, which would return to the initial trans conformation without net isomerization...
  84. pmc Ultrafast infrared spectroscopy reveals a key step for successful entry into the photocycle for photoactive yellow protein
    L J G W van Wilderen
    Department of Physics and Astronomy, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1081, 1081 HV, Amsterdam, The Netherlands
    Proc Natl Acad Sci U S A 103:15050-5. 2006
    ....
  85. ncbi Comment on "Gas-phase photochemistry of the photoactive yellow protein chromophore trans-p-coumaric acid"
    Mattijs de Groot
    van t Hoff Institute for Molecular Sciences, Faculty of Science, University of Amsterdam, Nieuwe Achtergracht 127 129, 1018 WV Amsterdam, The Netherlands
    J Phys Chem A 109:6135-6. 2005
  86. ncbi Photosynthetic pigment composition and photosystem II photochemistry of wheat ears
    Qingtao Lu
    Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China
    Plant Physiol Biochem 42:395-402. 2004
    The characteristics of pigment composition and photosystem II (PSII) photochemistry in the flag leaf and ear parts of wheat (Triticum aestivum L.) grown in the field was compared...
  87. ncbi Sensitive circular dichroism marker for the chromophore environment of photoactive yellow protein: assignment of the 307 and 318 nm bands to the n --> pi* transition of the carbonyl
    Berthold Borucki
    Biophysics Group, Physics Department, Freie Universitat Berlin, Arnimallee 14, D 14195 Berlin, Germany
    J Phys Chem B 109:629-33. 2005
    ..Thus, the 318 nm CD signal is a sensitive marker for the environment of the chromophore carbonyl, which samples various environments and configurations during the photocycle...
  88. ncbi The photochemistry of thymidylyl-(3'-5')-5-methyl-2'-deoxycytidine in aqueous solution
    Lech Celewicz
    Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco, CA 94143 0446, USA
    Photochem Photobiol 81:404-18. 2005
    The photochemistry of the dinucleoside monophosphate thymidylyl-(3'-5')-5-methyl-2'-deoxycytidine (Tpm5dC) has been studied in aqueous solution using both 254 nm and UV-B radiation...
  89. ncbi Ab initio excited-state dynamics of the photoactive yellow protein chromophore
    Chaehyuk Ko
    Department of Chemistry and the Beckman Institute, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    J Am Chem Soc 125:12710-1. 2003
    ....
  90. ncbi Photoisomerization of spiropyran for driving a molecular shuttle
    Weidong Zhou
    National Laboratory for Molecular Sciences, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beiijng 100080, P R China
    Org Lett 9:3929-32. 2007
    ..This movement process of the macrocycle is accompanied by reversible absorptive output signals which can be detected by the naked eye...
  91. ncbi Fluorescence and photochemistry of recombinant phytochrome from the cyanobacterium Synechocystis
    V Sineshchekov
    Biology Department, M V Lomonosov Moscow State University, Russia
    Photochem Photobiol 67:263-7. 1998
    ..These photochemical features are interpreted in terms of different activation barriers for the photoreaction in the Pr excited state...
  92. doi Photodynamics in complex environments: ab initio multiple spawning quantum mechanical/molecular mechanical dynamics
    Aaron M Virshup
    Department of Chemistry, Center for Biophysics and Computational Biology, University of Illinois, Urbana, Illinois 61801, USA
    J Phys Chem B 113:3280-91. 2009
    ..as funnels for population transfer between different electronic states, and play a central role in ultrafast photochemistry. Because most practical photochemistry occurs in solution and protein environments, it is important to ..
  93. doi Direct observation of lateral photovoltaic effect in nano-metal-films
    C Q Yu
    Department of Physics, Shanghai Jiao Tong University, Shanghai, PR China
    Opt Express 17:21712-22. 2009
    ..All the data and analyses in this study indicate that metal side LPE in MS structure has some natural superiorities to the semiconductor side LPE and may open many exciting opportunities for realizing multifunctional devices...
  94. ncbi Structural basis for the photochemistry of alpha-phycoerythrocyanin
    Marius Schmidt
    Physikdepartment E17, Technische Universitat Munchen, James Franck Strasse, 85747 Garching, Germany
    Biochemistry 46:416-23. 2007
    ..Interactions of the chromophore A and D pyrrole rings with flexible protein moieties are required for the formation and stabilization of the isomers. We predict that the results will hold for all photoactive biliproteins...
  95. ncbi A novel photoreaction mechanism for the circadian blue light photoreceptor Drosophila cryptochrome
    Alex Berndt
    Max Planck Institute of Molecular Physiology, Department of Structural Biology, Otto Hahn Strasse 11, 44227 Dortmund, Germany
    J Biol Chem 282:13011-21. 2007
    ..radical represents the light-activated state that mediates resetting of the Drosophila circadian clock...
  96. ncbi Ultrafast excited-state dynamics of the photoswitchable protein Dronpa
    Eduard Fron
    Department of Chemistry and Institute for Nanoscale Physics and Chemistry INPAC, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium
    J Am Chem Soc 129:4870-1. 2007
  97. ncbi Enhanced visible-light-induced photocatalytic disinfection of E. coli by carbon-sensitized nitrogen-doped titanium oxide
    Qi Li
    Department of Materials Science and Engineering, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    Environ Sci Technol 41:5050-6. 2007
    ..The enhanced photocatalytic activity is related to stronger visible light absorption of the carbon-sensitized TiON...
  98. ncbi Animal type 1 cryptochromes. Analysis of the redox state of the flavin cofactor by site-directed mutagenesis
    Nuri Ozturk
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 283:3256-63. 2008
    ....
  99. ncbi Enhanced antibactericidal function of W4+-doped titania-coated nickel ferrite composite nanoparticles: a biomaterial system
    B K Sunkara
    Center for Structural and Functional Materials and Chemical Engineering Department, University of Louisiana at Lafayette, P O Box 44130, Lafayette, LA 70504 4130, USA
    Acta Biomater 4:273-83. 2008
    ....
  100. ncbi Fluorescent proteins: maturation, photochemistry and photophysics
    S James Remington
    Institute of Molecular Biology and Department of Physics, University of Oregon, Eugene, OR 97403, USA
    Curr Opin Struct Biol 16:714-21. 2006
    ....
  101. ncbi Regulating gene expression with light-activated oligonucleotides
    XinJing Tang
    Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104 6323, USA
    Mol Biosyst 3:100-10. 2007
    ..Quantitative, laser-initiated methods for controlling DNA and RNA function will illuminate new areas in cell and developmental biology...

Research Grants69

  1. PHOTOSENSTIZATION MECHANISMS IN HYPOXIC MEDIA
    ROBERT REDMOND; Fiscal Year: 2003
    ..An understanding of subtle microenvironment effects on PS photophysics and photochemistry and development of strategies to reduce PDT- induced hypoxia or provide oxygen-independent phytotoxicity will ..
  2. HEME PROTEINS, MICROSPHERES, AND SYNTHETIC ANALOGS
    KENNETH SUSLICK; Fiscal Year: 2000
    ..Our exploration of the photochemistry of metalloporphyrins has created a new route to the formation of metal-oxo complexes and other high energy ..
  3. Bilirubin and Photobilirubin: Metabolism & Exretion
    Antony McDonagh; Fiscal Year: 2005
    ..These aims will be achieved by studying the chemistry, photochemistry, and metabolism of BR and specially designed synthetic model compounds both in vitro and in vivo in animals ..
  4. Electron Transfer in Iron and Copper Proteins
    Jay R Winkler; Fiscal Year: 2010
    ..e., Fe-oxo Compounds I and II) are often invoked. Protein labeling and laser flash-quench photochemistry will be used to develop new insights into the reactive intermediates in heme-thiolate mono-oxygenases...
  5. HEME PROTEINS AND THEIR SYNTHETIC ANALOGS
    KENNETH SUSLICK; Fiscal Year: 1993
    ..Our exploration of the photochemistry of metalloporphyrins has created a new route to the formation of metal-oxo complexes...
  6. ULTRAVIOLET LIGHT INDUCED PHENOMENA IN BIOMEMBRANES
    IRENE KOCHEVAR; Fiscal Year: 1999
    b>Photochemistry in cellular membranes is responsible for initiating many responses of cells to ultraviolet and visible radiation with and without added photosensitizing molecules...
  7. THE PHOTOBIOLOGY OF VITAMIN D3
    Michael Holick; Fiscal Year: 1993
    The long-term objective of this research program is to develop a better understanding of (a) the photochemistry and photobiology of vitamin D3 that occurs in the skin when humans are exposed to sunlight and (b) what physiologic functions ..
  8. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    KENNETH KARLIN; Fiscal Year: 2007
    ..ligand Cu(l)-chelates, (2) study of key ligand- Cu2+(O2-) (superoxide) solvent hydrogen bonding and photochemistry, (3) a major effort to unravel mechanistic details of ligand-Cu2+(O2-) substrate reactivity involving hydrogen-..
  9. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    KENNETH KARLIN; Fiscal Year: 2009
    ..ligand Cu(l)-chelates, (2) study of key ligand- Cu2+(O2-) (superoxide) solvent hydrogen bonding and photochemistry, (3) a major effort to unravel mechanistic details of ligand-Cu2+(O2-) substrate reactivity involving hydrogen-..
  10. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    KENNETH KARLIN; Fiscal Year: 2009
    ..ligand Cu(l)-chelates, (2) study of key ligand- Cu2+(O2-) (superoxide) solvent hydrogen bonding and photochemistry, (3) a major effort to unravel mechanistic details of ligand-Cu2+(O2-) substrate reactivity involving hydrogen-..
  11. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    Kenneth D Karlin; Fiscal Year: 2010
    ..ligand Cu(l)-chelates, (2) study of key ligand- Cu2+(O2-) (superoxide) solvent hydrogen bonding and photochemistry, (3) a major effort to unravel mechanistic details of ligand-Cu2+(O2-) substrate reactivity involving hydrogen-..
  12. Genomic Approaches to Neuronal Diversity and Plasticity
    Jingyue Ju; Fiscal Year: 2007
    ..The combined approach based on genomics, photochemistry, nanoscience and engineering, biochemistry, and neuroscience will be used to understand how neurons and ..
  13. ISOMERIC RETINOIDS, CAROTENOIDS, THEIR PROTEIN COMPLEXES
    Robert Liu; Fiscal Year: 2001
    ..Such knowledge is clearly important for prediction of photochemistry of polyenes, for synthetic applications and for a better understanding of the specific mode of reaction in ..
  14. Heme/Copper and Heme/Non-Heme Iron O2 and NO Reactivity
    KENNETH KARLIN; Fiscal Year: 2007
    ..of discrete heme/M compounds, their reactivity studies with O2 and NO, the coordination chemistry and the photochemistry of heme/M complexes, and the reductive O-O bond cleavage of heme/Cu/O2 adducts...
  15. Visibly Caged Bio-active Molecules and PDT
    Paul Jones; Fiscal Year: 2004
    ..To photoactivate thrombin and TPA, enzymes of ophthalmological relevance, using visible light. IV. To develop photochemistry capable of photoreleasing biologically active aldehydes and an in vitro demonstration of biological activity ..
  16. MOLECULAR MECHANISMS OF PHOTORECEPTOR FUNCTION
    BARRY KNOX; Fiscal Year: 2004
    ..The ability to introduce opsin mutants that have altered stability or photochemistry into rod cells will allow us to address several longstanding issues about rod photoreceptor behavior: ..
  17. Molecular characterization of mouse melanopsin and second messenger pathway.
    PHYLLIS ROBINSON; Fiscal Year: 2009
    ..This approach is designed to determine melanopsin's photochemistry, to elucidate the nature of the second messenger pathway activated by melanopsin, and to determine if there ..
  18. Molecular characterization of mouse melanopsin and second messenger pathway.
    Phyllis R Robinson; Fiscal Year: 2010
    ..This approach is designed to determine melanopsin's photochemistry, to elucidate the nature of the second messenger pathway activated by melanopsin, and to determine if there ..
  19. ULTRAFAST MULTIPHOTON LASER ACTIVATION SYSTEM
    WATT WEBB; Fiscal Year: 2001
    ..a select set of innovative biomedical and biotechnology research programs that are implemented by multiphoton photochemistry and photophysics...