photochemistry

Summary

Top Publications

  1. ncbi Photobleaching and photoactivation: following protein dynamics in living cells
    Jennifer Lippincott-Schwartz
    Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Cell Biol . 2003
  2. ncbi The retinal pigment epithelium in visual function
    Olaf Strauss
    Bereich Experimentelle Ophthalmologie, Klinik und Poliklinik fuer Augenheilkunde, Universitaetsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Physiol Rev 85:845-81. 2005
  3. ncbi Photochemistry of organic iron(III) complexing ligands in oceanic systems
    Katherine Barbeau
    Geosciences Research Division, Scripps Institution of Oceanography, University of California, San Diego, San Diego, CA, USA
    Photochem Photobiol 82:1505-16. 2006
  4. ncbi Photodynamic therapy: update 2006. Part 1: Photochemistry and photobiology
    P G Calzavara-Pinton
    Department of Dermatology, Azienda Ospedaliera Spedali Civili and University of Brescia, Piazzale Spedali Civili 1, 25123 Brescia, Italy
    J Eur Acad Dermatol Venereol 21:293-302. 2007
  5. ncbi Photochemical products in urban mixtures enhance inflammatory responses in lung cells
    Kenneth G Sexton
    Department of Environmental Science and Engineering, University of North Carolina at Chapel Hill, 27599, USA
    Inhal Toxicol 16:107-14. 2004
  6. ncbi Phytochrome-interacting factor 1 is a critical bHLH regulator of chlorophyll biosynthesis
    Enamul Huq
    Section of Molecular Cell and Developmental Biology and Institute of Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA
    Science 305:1937-41. 2004
  7. ncbi Engineering of a monomeric green-to-red photoactivatable fluorescent protein induced by blue light
    Nadya G Gurskaya
    Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, Moscow 117997, Russia
    Nat Biotechnol 24:461-5. 2006
  8. ncbi Effect of light on self-assembly of aqueous mixtures of sodium dodecyl sulfate and a cationic, bolaform surfactant containing azobenzene
    F Pierce Hubbard
    Department of Chemical and Biological Engineering, University of Madison Wisconsin, 1415 Engineering Drive, Madison, Wisconsin 53706 1691, USA
    Langmuir 23:4819-29. 2007
  9. ncbi Surface photochemistry: organic molecules within nanocavities of calixarenes
    Luis F Vieira Ferreira
    Centro de Química Física Molecular Complexo I, Inst Sup Téc, Universidade Tecnica de Lisboa, Av Rovisco Pais 1049 001 Lisboa, Portugal
    Curr Drug Discov Technol 4:229-45. 2007
  10. ncbi Vibrioferrin, an unusual marine siderophore: iron binding, photochemistry, and biological implications
    Shady A Amin
    Department of Chemistry and Biochemistry, San Diego State University, San Diego, California 92182 1030, USA
    Inorg Chem 48:11451-8. 2009

Research Grants

  1. PHOTOSENSTIZATION MECHANISMS IN HYPOXIC MEDIA
    ROBERT REDMOND; Fiscal Year: 2003
  2. HEME PROTEINS, MICROSPHERES, AND SYNTHETIC ANALOGS
    KENNETH SUSLICK; Fiscal Year: 2000
  3. Bilirubin and Photobilirubin: Metabolism & Exretion
    Antony McDonagh; Fiscal Year: 2005
  4. Electron Transfer in Iron and Copper Proteins
    Jay R Winkler; Fiscal Year: 2010
  5. HEME PROTEINS AND THEIR SYNTHETIC ANALOGS
    KENNETH SUSLICK; Fiscal Year: 1993
  6. ULTRAVIOLET LIGHT INDUCED PHENOMENA IN BIOMEMBRANES
    IRENE KOCHEVAR; Fiscal Year: 1999
  7. THE PHOTOBIOLOGY OF VITAMIN D3
    Michael Holick; Fiscal Year: 1993
  8. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    KENNETH KARLIN; Fiscal Year: 2007
  9. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    KENNETH KARLIN; Fiscal Year: 2009
  10. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    KENNETH KARLIN; Fiscal Year: 2009

Detail Information

Publications300 found, 100 shown here

  1. ncbi Photobleaching and photoactivation: following protein dynamics in living cells
    Jennifer Lippincott-Schwartz
    Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Cell Biol . 2003
    ..Widespread applications of these fluorescent-based methods are revealing new aspects of protein dynamics and the biological processes that they regulate...
  2. ncbi The retinal pigment epithelium in visual function
    Olaf Strauss
    Bereich Experimentelle Ophthalmologie, Klinik und Poliklinik fuer Augenheilkunde, Universitaetsklinikum Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Physiol Rev 85:845-81. 2005
    ..On the other hand, mutations in genes expressed in photoreceptors can lead to degenerations of the RPE. Thus both tissues can be regarded as a functional unit where both interacting partners depend on each other...
  3. ncbi Photochemistry of organic iron(III) complexing ligands in oceanic systems
    Katherine Barbeau
    Geosciences Research Division, Scripps Institution of Oceanography, University of California, San Diego, San Diego, CA, USA
    Photochem Photobiol 82:1505-16. 2006
    ..This review highlights recent findings, including both model ligand studies and experimentallobservational studies of the natural seawater ligand pool...
  4. ncbi Photodynamic therapy: update 2006. Part 1: Photochemistry and photobiology
    P G Calzavara-Pinton
    Department of Dermatology, Azienda Ospedaliera Spedali Civili and University of Brescia, Piazzale Spedali Civili 1, 25123 Brescia, Italy
    J Eur Acad Dermatol Venereol 21:293-302. 2007
    ..This paper provides an overview of the chemistry of the photosensitizers, the photobiology and photoimmunology of the photodynamic reaction as well as the photophysical characteristics of the light sources available for PDT...
  5. ncbi Photochemical products in urban mixtures enhance inflammatory responses in lung cells
    Kenneth G Sexton
    Department of Environmental Science and Engineering, University of North Carolina at Chapel Hill, 27599, USA
    Inhal Toxicol 16:107-14. 2004
    ..In the absence of such particles, these gaseous products remained mostly as gases. These experiments show that photochemically produced gaseous products do influence the toxic responses of the cells in the absence of particles...
  6. ncbi Phytochrome-interacting factor 1 is a critical bHLH regulator of chlorophyll biosynthesis
    Enamul Huq
    Section of Molecular Cell and Developmental Biology and Institute of Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA
    Science 305:1937-41. 2004
    ....
  7. ncbi Engineering of a monomeric green-to-red photoactivatable fluorescent protein induced by blue light
    Nadya G Gurskaya
    Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, Moscow 117997, Russia
    Nat Biotechnol 24:461-5. 2006
    ..We demonstrate the suitability of Dendra for protein labeling and tracking to quantitatively study dynamics of fibrillarin and vimentin in mammalian cells...
  8. ncbi Effect of light on self-assembly of aqueous mixtures of sodium dodecyl sulfate and a cationic, bolaform surfactant containing azobenzene
    F Pierce Hubbard
    Department of Chemical and Biological Engineering, University of Madison Wisconsin, 1415 Engineering Drive, Madison, Wisconsin 53706 1691, USA
    Langmuir 23:4819-29. 2007
    ..g., vesicles rich in trans-BTHA and SDS coexist with micelles rich in cis-BTHA and SDS). The results presented in this paper provide guidance for the design of light-tunable surfactants systems...
  9. ncbi Surface photochemistry: organic molecules within nanocavities of calixarenes
    Luis F Vieira Ferreira
    Centro de Química Física Molecular Complexo I, Inst Sup Téc, Universidade Tecnica de Lisboa, Av Rovisco Pais 1049 001 Lisboa, Portugal
    Curr Drug Discov Technol 4:229-45. 2007
    ..One of the main conclusions was that the solid support can deeply affect or even control the photochemistry of an adsorbed probe...
  10. ncbi Vibrioferrin, an unusual marine siderophore: iron binding, photochemistry, and biological implications
    Shady A Amin
    Department of Chemistry and Biochemistry, San Diego State University, San Diego, California 92182 1030, USA
    Inorg Chem 48:11451-8. 2009
    ..The consequences that these features have on bacterial-algal interactions with potential importance to understanding the origin and sustenance of harmful algal blooms are discussed...
  11. ncbi Photocontrol of single-chain DNA conformation in cell-mimicking microcompartments
    Matthieu Sollogoub
    , Laboratoire de Chimie Organique (UMR CNRS 7611, , 75005 Paris, France
    Chembiochem 9:1201-6. 2008
  12. ncbi Electric field quenching of carbon nanotube photoluminescence
    Anton V Naumov
    Applied Physics Program, Rice University, Houston, Texas 77005, USA
    Nano Lett 8:1527-31. 2008
    ..Photoluminescence intensity was found to follow a reciprocal hyperbolic cosine dependence on electric field...
  13. ncbi Prebiotic significance of extraterrestrial ice photochemistry: detection of hydantoin in organic residues
    Pierre de Marcellus
    Universite Paris Sud, Astrochimie et Origines, Institut d Astrophysique Spatiale, Orsay, France
    Astrobiology 11:847-54. 2011
    ..result, together with other related experiments reported recently, points to the potential importance of the photochemistry of interstellar "dirty" ices in the formation of organics in Solar System materials...
  14. ncbi Morphological changes in vesicles and release of an encapsulated compound triggered by a photoresponsive Malachite Green leuconitrile derivative
    Ryoko M Uda
    Department of Chemical Engineering, Nara National College of Technology, Yata 22, Yamato koriyama, Nara 639 1080, Japan
    Langmuir 26:5444-50. 2010
    ..Furthermore, irradiation of the Malachite Green derivative induces the release of a vesicle-encapsulated compound...
  15. ncbi Effect of denaturation on the photochemistry of pyrimidine bases in isolated DNA
    Thierry Douki
    Laboratoire Lesions des Acides Nucleiques, Service de Chimie Inorganique et Biologique UMR E 3 CEA UJF, CEA DSM Département de Recherche Fondamentale sur la Matière Condensée, CEA Grenoble, 38054 Grenoble Cedex 9, France
    J Photochem Photobiol B 82:45-52. 2006
    The influence of denaturation on DNA photochemistry was studied by quantifying the yield of formation of all possible bipyrimidine photolesions within isolated genomic DNA samples exposed to UVC radiation...
  16. ncbi Comparative photochemistry of animal type 1 and type 4 cryptochromes
    Nuri Ozturk
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    Biochemistry 48:8585-93. 2009
    ..Although the photochemistry of plant CRYs has been studied in some detail, the photochemical behavior of animal cryptochromes remains ..
  17. ncbi Adhesion and migration of ovarian cancer cells on crosslinked laminin fibers nanofabricated by multiphoton excited photochemistry
    Xiyi Chen
    Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030, USA
    Integr Biol (Camb) 1:469-76. 2009
    ..To explore this possibility, we have used multiphoton excited photochemistry (MPE) to synthesize models of the ovarian basal lamina consisting of crosslinked laminin nanofibers to ..
  18. ncbi EosFP, a fluorescent marker protein with UV-inducible green-to-red fluorescence conversion
    Jörg Wiedenmann
    Department of General Zoology and Endocrinology, University of Ulm, 89069 Ulm, Germany
    Proc Natl Acad Sci U S A 101:15905-10. 2004
    ..The possibility to locally change the emission wavelength by focused UV light makes EosFP a superb marker for experiments aimed at tracking the movements of biomolecules within the living cell...
  19. ncbi Photochemistry, remotely sensed physiological reflectance index and de-epoxidation state of the xanthophyll cycle in Quercus coccifera under intense drought
    José Javier Peguero-Pina
    Unidad de Recursos Forestales, Centro de Investigación y Tecnología Agroalimentaria, Gobierno de Aragón, Apdo 727, 50080 Saragossa, Spain
    Oecologia 156:1-11. 2008
    ..It is concluded that, contrary to early reports, PRI is a sensible, indirect, non-destructive water stress indicator, even in plants experiencing intense drought...
  20. ncbi The effects of the bacterial interaction with visible-light responsive titania photocatalyst on the bactericidal performance
    Chia Liang Cheng
    Department of Physics, National Dong Hwa University, Hualien, Taiwan
    J Biomed Sci 16:7. 2009
    ..These findings suggest the created materials with high bacterial interaction ability might be a useful strategy to improve the antimicrobial activity of visible-light-activated TiO2...
  21. ncbi Gas-phase photochemistry of the photoactive yellow protein chromophore trans-p-coumaric acid
    Wendy L Ryan
    Department of Chemistry, University of Chicago, Chicago, Illinois 60637, USA
    J Am Chem Soc 124:6194-201. 2002
    ..Although trans-CA was excited in all three regions, a significant cis-CA peak appeared only in region II, though a small cis peak was observed in region III...
  22. ncbi Reversible photoswitching in a cell-sized vesicle
    Tsutomu Hamada
    Department of Physics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan
    Langmuir 21:7626-8. 2005
    ..The mechanism of this reversible photoswitching in the vesicle morphology is interpreted in terms of a change in the effective cross-sectional area of the photosensitive molecule...
  23. ncbi Radiometric quantities and units used in photobiology and photochemistry: recommendations of the Commission Internationale de L'Eclairage (International Commission on Illumination)
    David H Sliney
    International Commission on Illumination CIE, Vienna, Austria
    Photochem Photobiol 83:425-32. 2007
    ..As photobiology and photochemistry both represent the fusion of several scientific disciplines, it is not surprising that the physical terms used ..
  24. ncbi Environmental carcinogenic polycyclic aromatic hydrocarbons: photochemistry and phototoxicity
    Hongtao Yu
    Department of Chemistry, Jackson State University, Jackson, MS 39217, USA
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 20:149-83. 2002
    ..Although many books and reviews on these subjects have been published, PAH photochemistry and phototoxicity have received much less attention...
  25. ncbi Kinetic study on photocatalytic degradation of C.I. Acid Yellow 23 by ZnO photocatalyst
    M A Behnajady
    Department of Applied Chemistry, Islamic Azad University, Tabriz, Islamic Republic of Iran
    J Hazard Mater 133:226-32. 2006
    ..A comparison between experimental and calculated apparent reaction rate constants shows that the results obtained from the L-H modified model are in good agreement with experimental data...
  26. ncbi Heterogeneous photocatalyzed degradation of uracil and 5-bromouracil in aqueous suspensions of titanium dioxide
    H K Singh
    Department of Chemistry, Aligarh Muslim University, Aligarh 202002, India
    J Hazard Mater 142:425-30. 2007
    ..Photocatalyst Degussa P25 was found to be more efficient for the degradation of both compounds as compared with other TiO2 powders such as UV100, PC500 and TTP...
  27. ncbi Synthesis and photochemistry of a two-position Ru(terpy)(phen)(L)2+ scorpionate complex
    Sylvestre Bonnet
    , UMR 7513 du CNRS, Institut Le Bel, , 4 rue Blaise Pascal, 67000 Strasbourg Cedex, France
    Inorg Chem 45:4024-34. 2006
    ..Thermal back-coordination of the tail was investigated in the dark. It took place quantitatively from the corresponding ruthenium chloride complex by trapping of the anion with silver salts...
  28. ncbi Photocatalytic activity for degradation of nitrogen oxides over visible light responsive titania-based photocatalysts
    Yu Ming Lin
    Center for Environmental, Safety and Health Technology Development, Industrial Technology Research Institute, Room 204, Building 32, 195, Section 4, Chung Hsing Road, Chutung, Hsinchu 310, Taiwan
    Environ Sci Technol 40:1616-21. 2006
    ..Rinsing with water was responsible for the restored reactivity of prepared TiO2 catalysts for NO(x) degradation...
  29. ncbi H-aggregation of azobenzene-substituted amphiphiles in vesicular membranes
    Johanna M Kuiper
    Stratingh Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands
    Langmuir 20:1152-60. 2004
    ....
  30. ncbi Production and scavenging of reactive oxygen species in chloroplasts and their functions
    Kozi Asada
    Faculty of Life Science and Biotechnology, Fukuyama University, Fukuyama 729-0292, Japan
    Plant Physiol 141:391-6. 2006
  31. ncbi Photoreversible DNA condensation using light-responsive surfactants
    Anne-Laure M Le Ny
    Department of Chemical Engineering and Material Sciences, University of Southern California, Los Angeles, California 90089-1211, USA
    J Am Chem Soc 128:6400-8. 2006
    ..The combined results clearly show the ability to control the interaction between DNA and the complexing agent and, therefore, DNA condensation with light...
  32. ncbi Crystallographic analysis of primary visual photochemistry
    Hitoshi Nakamichi
    Biological Information Research Center, National Institute of Advanced Industrial Science and Technology, 2-41-6 Aomi, Koto-ku, Tokyo 135-0064, Japan
    Angew Chem Int Ed Engl 45:4270-3. 2006
  33. ncbi Controlling photochemistry with distinct hydrophobic nanoenvironments
    Lakshmi S Kaanumalle
    Department of Chemistry, Tulane University, New Orleans, Louisiana 70118, USA
    J Am Chem Soc 126:14366-7. 2004
    ..Encapsulated guests such as dibenzyl ketones reside in an essentially dry environment, and upon irradiation, undergo rearrangement processes that are templated by the shape of the 1 nm x 2 nm cavity...
  34. ncbi Structural evolution of the chromophore in the primary stages of trans/cis isomerization in photoactive yellow protein
    Karsten Heyne
    Max Born Institut fur Nichtlineare Optik und Kurzzeitspektroskopie, Max Born Strasse 2A, D 12489 Berlin, Germany
    J Am Chem Soc 127:18100-6. 2005
    ....
  35. ncbi Solvent effect on the excited-state dynamics of analogues of the photoactive yellow protein chromophore
    Agathe Espagne
    , , 24 rue Lhomond, 75231 Paris Cedex 05, France
    J Phys Chem A 110:3393-404. 2006
    ..The excited-state deactivation of pCT- would lead to the formation of a ground-state intermediate at the "perp" geometry, which would return to the initial trans conformation without net isomerization...
  36. ncbi Ab initio excited-state dynamics of the photoactive yellow protein chromophore
    Chaehyuk Ko
    Department of Chemistry and the Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA
    J Am Chem Soc 125:12710-1. 2003
    ....
  37. ncbi Ultrafast photoisomerization of photoactive yellow protein chromophore analogues in solution: influence of the protonation state
    Agathe Espagne
    UMR CNRS-ENS 8640 PASTEUR, , , 24 rue Lhomond, 75231 Paris Cedex 05, France
    Chemphyschem 7:1717-26. 2006
    ..A trans-to-cis isomerization mechanism involving mainly the ethylenic double-bond torsion and/or solvation is proposed for the anionic forms, whereas "concerted" intramolecular motions are proposed for the neutral forms...
  38. ncbi The photochemistry of thymidylyl-(3'-5')-5-methyl-2'-deoxycytidine in aqueous solution
    Lech Celewicz
    Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco, CA 94143-0446, USA
    Photochem Photobiol 81:404-18. 2005
    The photochemistry of the dinucleoside monophosphate thymidylyl-(3'-5')-5-methyl-2'-deoxycytidine (Tpm5dC) has been studied in aqueous solution using both 254 nm and UV-B radiation...
  39. ncbi Photosynthetic pigment composition and photosystem II photochemistry of wheat ears
    Qingtao Lu
    Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China
    Plant Physiol Biochem 42:395-402. 2004
    The characteristics of pigment composition and photosystem II (PSII) photochemistry in the flag leaf and ear parts of wheat (Triticum aestivum L.) grown in the field was compared...
  40. ncbi Ultrafast infrared spectroscopy reveals a key step for successful entry into the photocycle for photoactive yellow protein
    L J G W van Wilderen
    Department of Physics and Astronomy, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1081, 1081 HV, Amsterdam, The Netherlands
    Proc Natl Acad Sci U S A 103:15050-5. 2006
    ....
  41. ncbi Comment on "Gas-phase photochemistry of the photoactive yellow protein chromophore trans-p-coumaric acid"
    Mattijs de Groot
    Van't Hoff Institute for Molecular Sciences, Faculty of Science, University of Amsterdam, Nieuwe Achtergracht 127-129, 1018 WV Amsterdam, The Netherlands
    J Phys Chem A 109:6135-6. 2005
  42. ncbi Sensitive circular dichroism marker for the chromophore environment of photoactive yellow protein: assignment of the 307 and 318 nm bands to the n --> pi* transition of the carbonyl
    Berthold Borucki
    Biophysics Group, Physics Department, , Arnimallee 14, D-14195 Berlin, Germany
    J Phys Chem B 109:629-33. 2005
    ..Thus, the 318 nm CD signal is a sensitive marker for the environment of the chromophore carbonyl, which samples various environments and configurations during the photocycle...
  43. ncbi Photoisomerization of spiropyran for driving a molecular shuttle
    Weidong Zhou
    National Laboratory for Molecular Sciences, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beiijng 100080, P R China
    Org Lett 9:3929-32. 2007
    ..This movement process of the macrocycle is accompanied by reversible absorptive output signals which can be detected by the naked eye...
  44. ncbi Photodynamics in complex environments: ab initio multiple spawning quantum mechanical/molecular mechanical dynamics
    Aaron M Virshup
    Department of Chemistry, Center for Biophysics and Computational Biology, University of Illinois, Urbana, Illinois 61801, USA
    J Phys Chem B 113:3280-91. 2009
    ..as funnels for population transfer between different electronic states, and play a central role in ultrafast photochemistry. Because most practical photochemistry occurs in solution and protein environments, it is important to ..
  45. ncbi Direct observation of lateral photovoltaic effect in nano-metal-films
    C Q Yu
    Department of Physics, Shanghai Jiao Tong University, Shanghai, PR China
    Opt Express 17:21712-22. 2009
    ..All the data and analyses in this study indicate that metal side LPE in MS structure has some natural superiorities to the semiconductor side LPE and may open many exciting opportunities for realizing multifunctional devices...
  46. ncbi Fluorescence and photochemistry of recombinant phytochrome from the cyanobacterium Synechocystis
    V Sineshchekov
    Biology Department, M V Lomonosov Moscow State University, Russia
    Photochem Photobiol 67:263-7. 1998
    ..These photochemical features are interpreted in terms of different activation barriers for the photoreaction in the Pr excited state...
  47. ncbi Regulating gene expression with light-activated oligonucleotides
    XinJing Tang
    Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104 6323, USA
    Mol Biosyst 3:100-10. 2007
    ..Quantitative, laser-initiated methods for controlling DNA and RNA function will illuminate new areas in cell and developmental biology...
  48. ncbi A novel photoreaction mechanism for the circadian blue light photoreceptor Drosophila cryptochrome
    Alex Berndt
    Max Planck Institute of Molecular Physiology, Department of Structural Biology, Otto Hahn Strasse 11, 44227 Dortmund, Germany
    J Biol Chem 282:13011-21. 2007
    ..radical represents the light-activated state that mediates resetting of the Drosophila circadian clock...
  49. ncbi Ultrafast excited-state dynamics of the photoswitchable protein Dronpa
    Eduard Fron
    Department of Chemistry and Institute for Nanoscale Physics and Chemistry (INPAC, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium
    J Am Chem Soc 129:4870-1. 2007
  50. ncbi Formation and function of flavin anion radical in cryptochrome 1 blue-light photoreceptor of monarch butterfly
    Sang Hun Song
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 282:17608-12. 2007
    ....
  51. ncbi Structural basis for the photochemistry of alpha-phycoerythrocyanin
    Marius Schmidt
    Physikdepartment E17, Technische Universitat Munchen, James Franck Strasse, 85747 Garching, Germany
    Biochemistry 46:416-23. 2007
    ..Interactions of the chromophore A and D pyrrole rings with flexible protein moieties are required for the formation and stabilization of the isomers. We predict that the results will hold for all photoactive biliproteins...
  52. ncbi Ultrafast deactivation of an excited cytosine-guanine base pair in DNA
    Gerrit Groenhof
    Contribution from the Department of Theoretical and Computational Biophysics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, D 37077 Gottingen, Germany
    J Am Chem Soc 129:6812-9. 2007
    ..In vacuo, decay occurs after a complete proton transfer, whereas in DNA, decay can also occur much earlier. The origin of this effect lies in the temporal electrostatic stabilization of dipole in the charge-transfer state in DNA...
  53. ncbi Vancomycin derivative photopolymerized to titanium kills S. epidermidis
    McKinley C Lawson
    Department of Chemical and Biological Engineering, University of Colorado, Boulder, CO 80309, USA
    Clin Orthop Relat Res 461:96-105. 2007
    ..This coating method allows a loading dose several thousand times larger than that achieved with monolayer vancomycin coupling approaches and holds promise for the treatment of orthopaedic infections...
  54. ncbi Visible light inactivation of bacteria and fungi by modified titanium dioxide
    Dariusz Mitoraj
    Faculty of Chemistry, Jagiellonian University, ul Ingardena 3, 30 060 Krakow, Poland
    Photochem Photobiol Sci 6:642-8. 2007
    ..faecalis>>C. albicans approximately A. niger. This sequence results most probably from differences in cell wall or cell membrane structures in these microorganisms and is not related to the ability of catalase production...
  55. ncbi Effects of the binding of alpha/beta-type small, acid-soluble spore proteins on the photochemistry of DNA in spores of Bacillus subtilis and in vitro
    Thierry Douki
    Laboratoire Lesions des Acides Nucleiques, Service de Chimie Inorganique et Biologique, CEA DSM Département de Recherche Fondamentale sur la Matière Condensée, CEA Grenoble, 17 Avenue des Martyrs, 38054 Grenoble Cedex, France
    Photochem Photobiol 81:163-9. 2005
    ..The novel photochemistry of spore DNA is accounted for in part by its reduced hydration, but largely by the saturation of spore DNA ..
  56. ncbi Caged compounds: photorelease technology for control of cellular chemistry and physiology
    Graham C R Ellis-Davies
    Department of Pharmacology and Physiology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, USA
    Nat Methods 4:619-28. 2007
    ..Here I describe important examples of widely used caged compounds, their design features and synthesis, as well as practical details of how to use them with living cells...
  57. ncbi Fluorescent proteins: maturation, photochemistry and photophysics
    S James Remington
    Institute of Molecular Biology and Department of Physics, University of Oregon, Eugene, OR 97403, USA
    Curr Opin Struct Biol 16:714-21. 2006
    ....
  58. ncbi Characterization of photosynthetic pigment composition, photosystem II photochemistry and thermal energy dissipation during leaf senescence of wheat plants grown in the field
    C Lu
    Photosynthesis Research Centre, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, PR China
    J Exp Bot 52:1805-10. 2001
    Photosynthetic pigment composition and photosystem II (PSII) photochemistry were characterized during the flag leaf senescence of wheat plants grown in the field...
  59. ncbi Recent advances in urocanic acid photochemistry, photobiology and photoimmunology
    Neil K Gibbs
    Dermatological Sciences, University of Manchester Medical School, Stopford Building, Oxford Road, Manchester, UK M13 9PT
    Photochem Photobiol Sci 7:655-67. 2008
    ..With its intriguing photochemistry, its role in immunosuppression and skin cancer development, and skin barrier function, UCA continues to be the ..
  60. ncbi Photodegradation of methyl tert-butyl ether (MTBE) by UV/H2O2 and UV/TiO2
    Qinhai Hu
    Department of Environmental Engineering, Zhejiang University, Hangzhou 310029, People s Republic of China
    J Hazard Mater 154:795-803. 2008
    ..The pseudo first-order rate constants linearly increased with the increase in the molar ratio of [H2O2]0 to [MTBE]0 in UV/H2O2 system and linearly increased with the decrease in [MTBE]0 in UV/TiO2 system...
  61. ncbi Ultrafast dynamics of flavins in five redox states
    Ya Ting Kao
    Department of Physics, The Ohio State University, 191 West Woodruff Avenue, Columbus, Ohio 43210, USA
    J Am Chem Soc 130:13132-9. 2008
    ....
  62. ncbi Animal type 1 cryptochromes. Analysis of the redox state of the flavin cofactor by site-directed mutagenesis
    Nuri Ozturk
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 283:3256-63. 2008
    ....
  63. ncbi Enantioselective magnetochiral photochemistry
    G L Rikken
    Grenoble High Magnetic Field Laboratory, Max Planck Institut fur Festkorperforschung CNRS, France
    Nature 405:932-5. 2000
    ....
  64. ncbi Photosystem II photochemistry and photosynthetic pigment composition in salt-adapted halophyte Artimisia anethifolia grown under outdoor conditions
    Congming Lu
    Photosynthesis Research Centre, Institute of Botany, Chinese Academy of Sciences, Beijing, China
    J Plant Physiol 160:403-8. 2003
    The effects of high salinity (0-400 mmol/L NaCl) on photosystem II (PSII) photochemistry and photosynthetic pigment composition were investigated in the halophyte Artimisia anethifolia grown under outdoor conditions and exposed to full ..
  65. ncbi Delivery of siRNA to the target cell cytoplasm: photochemical internalization facilitates endosomal escape and improves silencing efficiency, in vitro and in vivo
    S Oliveira
    Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University Faculty of Science, PO Box 80 082, 3508 TB Utrecht, The Netherlands
    Curr Pharm Des 14:3686-97. 2008
    ..Finally, concluding remarks focus on the advantages of employing a technique such as PCI to enhance the endosomal escape of siRNA molecules...
  66. ncbi Gene inactivation by multiphoton-targeted photochemistry
    M W Berns
    Beckman Laser Institute and Medical Clinic and Center for Biomedical Engineering, University of California, Irvine 92612 1475, USA
    Proc Natl Acad Sci U S A 97:9504-7. 2000
    Multiphoton-targeted photochemistry was used to selectively inactivate the expression of genes in vertebrate cells...
  67. ncbi Enhanced antibactericidal function of W4+-doped titania-coated nickel ferrite composite nanoparticles: a biomaterial system
    B K Sunkara
    Center for Structural and Functional Materials and Chemical Engineering Department, University of Louisiana at Lafayette, P O Box 44130, Lafayette, LA 70504 4130, USA
    Acta Biomater 4:273-83. 2008
    ....
  68. ncbi Enhanced visible-light-induced photocatalytic disinfection of E. coli by carbon-sensitized nitrogen-doped titanium oxide
    Qi Li
    Department of Materials Science and Engineering, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    Environ Sci Technol 41:5050-6. 2007
    ..The enhanced photocatalytic activity is related to stronger visible light absorption of the carbon-sensitized TiON...
  69. ncbi Photochemistry and photoinduced proton-transfer by pharaonis phoborhodopsin
    N Kamo
    Laboratory of Biophysical Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, 060 0812, Japan
    Biochemistry (Mosc) 66:1277-82. 2001
    ..ppR or pR has absorption maximum at approximately 500 nm, which is blue-shifted from those of other archaeal rhodopsins. The molecular mechanism of this color regulation is not yet solved...
  70. ncbi Photo-induced protonation/deprotonation in the GFP-like fluorescent protein Dronpa: mechanism responsible for the reversible photoswitching
    Satoshi Habuchi
    Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium
    Photochem Photobiol Sci 5:567-76. 2006
    ..Our results demonstrate that Dronpa holds its outstanding photoswitching properties, based on a photo-induced protonation/deprotonation process, even at the single-molecule level...
  71. ncbi Surface grafted antibodies: controlled architecture permits enhanced antigen detection
    Robert P Sebra
    Langmuir 21:10907-11. 2005
    ..Finally, the addition of PEG spacers between the acrylate functionality and the pendant detection antibodies was tuned to enhance the detection of a short-half-life molecule, glucagon, in a complex biological environment, plasma...
  72. ncbi Anti-microbial active composite nanoparticles with magnetic core and photocatalytic shell: TiO2-NiFe2O4 biomaterial system
    S Rana
    Center for Structural and Functional Materials, University of Louisiana at Lafayette, P.O. Box 44130, Lafayette, LA 70504-4130, USA
    Acta Biomater 1:691-703. 2005
    ....
  73. ncbi Reversible photocontrol of deoxyribozyme-catalyzed RNA cleavage under multiple-turnover conditions
    Sonja Keiper
    School of Chemistry and Chemical Engineering, Queen's University Belfast, Belfast BT9 5AG, UK
    Angew Chem Int Ed Engl 45:3306-9. 2006
  74. ncbi 8-Bromo-7-hydroxyquinoline as a photoremovable protecting group for physiological use: mechanism and scope
    Yue Zhu
    Department of Chemistry, University of Georgia, Athens, 30602-2556, USA
    J Am Chem Soc 128:4267-76. 2006
    ..BHQ has the requisite photochemical and photophysical properties as a photoremovable protecting group to regulate the action of biological effectors in cell and tissue culture with light, especially 2PE...
  75. ncbi Visible-light-induced bactericidal activity of a nitrogen-doped titanium photocatalyst against human pathogens
    Ming-Show Wong
    Department of Materials Science and Engineering, National Dong-Hwa University, Hualien, Taiwan
    Appl Environ Microbiol 72:6111-6. 2006
    ..These findings suggest that nitrogen-doped TiO(2) has potential application in the development of alternative disinfectants for environmental and medical usages...
  76. ncbi Light-activated RNA interference
    Samit Shah
    Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri, Kansas City, Kansas City, MO 64110, USA
    Angew Chem Int Ed Engl 44:1328-32. 2005
  77. ncbi Role of lipid hydroperoxides in photo-oxidative stress signaling
    Albert W Girotti
    Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, U S A
    Antioxid Redox Signal 6:301-10. 2004
    ..g., in mitochondria, LOOHs may act as early mediators of apoptotic cell death. This review will focus on these various aspects, with special attention to the role of LOOHs in photooxidative signaling...
  78. ncbi Dechlorination pathways of ortho-substituted PCBs by UV irradiation in n-hexane and their correlation to the charge distribution on carbon atom
    Fang Cheng Chang
    Department of Agricultural Chemistry, National Taiwan University, 1, Sec. 4, Roosevelt Road, 10617, Taipei, Taiwan
    Chemosphere 51:775-84. 2003
    ..A lot of chlorine atoms attached PCB, the dechlorination was found to occur prior to the carbon with higher charge distribution at the benzene ring with more chlorine atoms attached...
  79. ncbi Structure, dynamics, and energetics of the primary photochemistry of photosystem II of oxygenic photosynthesis
    Bruce A Diner
    CR and D, Experimental Station, E I du Pont de Nemours and Co, Wilmington, Delaware 19880 0173, USA
    Annu Rev Plant Biol 53:551-80. 2002
    ....
  80. ncbi Deactivation behavior and excited-state properties of (coumarin-4-yl)methyl derivatives. 2. Photocleavage of selected (coumarin-4-yl)methyl-caged adenosine cyclic 3',5'-monophosphates with fluorescence enhancement
    Torsten Eckardt
    Institute of Molecular Pharmacology, , D-13125 Berlin, Germany
    J Org Chem 67:703-10. 2002
    ..The rate constant for the ester cleavage and liberation of cAMP is about 10(9) s(-1), estimated for the axial isomer of 6 by analysis of the fluorescence increase of the alcohol 12 formed upon laser pulse photolysis...
  81. ncbi Pattern of 4-thiouridine-induced cross-linking in 16S ribosomal RNA in the Escherichia coli 30S subunit
    Kavita Nanda
    Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, North Carolina 27695-7622, USA
    Biochemistry 43:8923-34. 2004
    ..The relatively small number of s(4)U-mediated cross-links is probably determined by the organization of the RNA in the 30S subunit, which allows RNA conformational flexibility needed for cross-link formation in just a limited region...
  82. ncbi Triggering DNAzymes with light: a photoactive C8 thioether-linked adenosine
    Richard Ting
    Department of Chemistry, The University of British Columbia, Vancouver, BC, V6T-1Z1, Canada
    J Am Chem Soc 126:12720-1. 2004
    ..This adenosine, which affords significant control of catalytic reactivation of a DNAzyme, may find general use in photodecaging other biological systems...
  83. ncbi Photolabile precursors of cyclic nucleotides with high aqueous solubility and stability
    Lijuan Wang
    Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    J Org Chem 67:3474-8. 2002
    ..The photolysis quantum yields are in the range 0.15-0.24, and the product release rate upon flash photolysis is 1.7 s(-1) at pH 7.0, 20 degrees C...
  84. ncbi A genetically encoded photocaged amino acid
    Ning Wu
    Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    J Am Chem Soc 126:14306-7. 2004
    ....
  85. ncbi Phototriggering of caged fluorescent oligodeoxynucleotides
    XinJing Tang
    Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, USA
    Org Lett 7:279-82. 2005
    ..Caged fluorescent oligodeoxynucleotides (CFOs) will allow many DNA processes to be controlled with light...
  86. ncbi Photochemistry of retinal chromophore in mouse melanopsin
    Marquis T Walker
    Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, MD 21250, USA
    Proc Natl Acad Sci U S A 105:8861-5. 2008
    ....
  87. ncbi Photoactivated gene expression for cell fate mapping and cell manipulation
    J Minden
    Department of Biological Sciences and Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, Pittsburgh, PA, USA
    Sci STKE 2000:pl1. 2000
    ..The methods for purifying, caging, injection, and photoactivation of the GAL4VP16 protein, and methods for the visualization of marked cells are described in detail...
  88. ncbi Characterization of psaI and psaL mutants of Synechococcus sp. strain PCC 7002: a new model for state transitions in cyanobacteria
    W M Schluchter
    Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park 16802, USA
    Photochem Photobiol 64:53-66. 1996
    ..A "mobile-PS I" model for state transitions that incorporates these ideas is discussed...
  89. ncbi Degradation of 2,4-dichlorophenol with a novel TiO2/Ti-Fe-graphite felt photoelectrocatalytic oxidation process
    Bao xiu Zhao
    School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China
    J Environ Sci (China) 19:1020-4. 2007
    ..So, it revealed that the degradation of 2,4-DCP was improved greatly by photoelectrical cooperation effect. By the investigation of pH, it showed that this integrative process could work well in a wide pH range from pH 3 to pH 9...
  90. ncbi Pulsed discharge plasma induced Fenton-like reactions for the enhancement of the degradation of 4-chlorophenol in water
    Xiaolong Hao
    Institute of Environmental Pollution Control Technologies, Xixi Campus, Zhejiang University, Hangzhou 310028, Zhejiang, PR China
    Chemosphere 66:2185-92. 2007
    ..e. 1,4-hydroquinone and 1,4-benzoquinone...
  91. ncbi Solid-state, planar photoelectrocatalytic devices using a nanosized TiO2 layer
    Jing Shang
    Department of Environmental Sciences, State Key Joint Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences, Peking University, Beijing 100871, People s Republic of China
    Environ Sci Technol 41:7876-80. 2007
    ....
  92. ncbi "Lock and key control" of photochromic reactivity by controlling the oxidation/reduction state
    Xiaochuan Li
    College of Chemistry and Environmental Science, Henan Normal University, Xinxiang, Henan, 453007, People s Republic of China
    Org Lett 10:3639-42. 2008
    ..Reactivated photochromic reactivity was obtained by deoxidization of the S, S-dioxide moieties. The suppressed photoactivity of the oxidation state was attributed to the stronger intramolecular hydrogen bonding interactions...
  93. ncbi Photodegradation of the acaricide abamectin: a kinetic study
    Juan Pablo Escalada
    Unidad Académica Río Gallegos, Universidad Nacional de la Patagonia Austral, 9400 Río Gallegos, Argentina
    J Agric Food Chem 56:7355-9. 2008
    ..5 x 10(5) M(-1) s(-1). This value is similar to those reported for the rate constants of the reactions of O2((1)Delta(g)) with isolated double bonds or conjugated dienes and points to similar processes in the case of abamectin...
  94. ncbi The physical and chemical properties of eumelanin
    Paul Meredith
    Soft Condensed Matter Physics Group, School of Physical Sciences, University of Queensland, Brisbane, Australia
    Pigment Cell Res 19:572-94. 2006
    ..We are engaged in such an endeavor for the case of eumelanin...
  95. ncbi CO Preferential oxidation promoted by UV irradiation in the presence of H2 over Au/TiO2
    Wenxin Dai
    Research Institute of Photocatalysis, State Key Laboratory Breeding Base of Photocatalysis, Fuzhou University, Fuzhou, 350002, China
    Phys Chem Chem Phys 10:3256-62. 2008
    ..e., the dissociative chemisorption H on Au (Au-H) could be desorbed at the H(2) molecule via accepting the photogenerated electrons from TiO(2)...
  96. ncbi Photocatalytic paper from colloidal TiO(2)--fact or fantasy
    Robert Pelton
    McMaster University, Department of Chemical Engineering, 1280 Main St W, Hamilton, Ontario, Canada L8S 4L7
    Adv Colloid Interface Sci 127:43-53. 2006
    ..Another theme is the use of multiple approaches, such as zeolites, for enhanced mineralization, and metals, such as silver and copper, for enhanced photocatalytic disinfection...
  97. ncbi The use of oxyhalogen in photocatalytic reaction to remove o-chloroaniline in TiO2 dispersion
    W K Choy
    Department of Civil and Structural Engineering, Research Centre for Environmental Technology and Management, The Hong Kong Polytechnic University, Hung Hom, Hong Kong
    Chemosphere 66:2106-13. 2007
    ..A mathematics model was successfully established for the prediction of the two-stage decay of o-ClA in UV/TiO2/IO3(-) with any designed [IO3(-)] concentration...
  98. ncbi Oxidation of aromatic alcohols in irradiated aqueous suspensions of commercial and home-prepared rutile TiO(2): a selectivity study
    Vincenzo Augugliaro
    Schiavello Grillone Photocatalysis Group, Dipartimento di Ingegneria Chimica dei Processi e dei Materiali, Universita degli Studi di Palermo, Viale delle Scienze, Palermo, Italy
    Chemistry 14:4640-6. 2008
    ..We have attempted to explain the different reaction rate and selectivity observed for MBA and BA...
  99. ncbi Enhanced photocatalytic degradation of dye pollutants under visible irradiation on Al(III)-modified TiO2: structure, interaction, and interfacial electron transfer
    Dan Zhao
    Beijing National Laboratory for Molecular Sciences, Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Sciences CAS, Beijing 100080, China
    Environ Sci Technol 42:308-14. 2008
    ..Structure with carboxylate as anchoring group and amino group as electron donor is favorable for degradation. The mechanistic details are discussed on the basis of experimental results...
  100. ncbi Effect of UV and visible light on photocatalytic reduction of lead and cadmium over titania based binary oxide materials
    T Mishra
    National Metallurgical Laboratory, Jamshedpur 831007, Jharkhand, India
    J Colloid Interface Sci 316:80-4. 2007
    ..Thus the above study indicates that the presence of certain oxides in low quantity (10 wt%) with titania can facilitates the photocatalytic process selectively in UV as well as visible light...
  101. ncbi Photocatalytic performance of Sn-doped TiO2 nanostructured mono and double layer thin films for Malachite Green dye degradation under UV and vis-lights
    F Sayilkan
    Inonu University, Faculty of Education, Department of Science, 44280 Malatya, Turkey
    J Hazard Mater 144:140-6. 2007
    ..The results also proved that the hydrothermally synthesized nano-TiO(2) particles are fully anatase crystalline form and are easily dispersed in water. The results also reveal that the coated surfaces have hydrophilic property...

Research Grants69

  1. PHOTOSENSTIZATION MECHANISMS IN HYPOXIC MEDIA
    ROBERT REDMOND; Fiscal Year: 2003
    ..An understanding of subtle microenvironment effects on PS photophysics and photochemistry and development of strategies to reduce PDT- induced hypoxia or provide oxygen-independent phytotoxicity will ..
  2. HEME PROTEINS, MICROSPHERES, AND SYNTHETIC ANALOGS
    KENNETH SUSLICK; Fiscal Year: 2000
    ..Our exploration of the photochemistry of metalloporphyrins has created a new route to the formation of metal-oxo complexes and other high energy ..
  3. Bilirubin and Photobilirubin: Metabolism & Exretion
    Antony McDonagh; Fiscal Year: 2005
    ..These aims will be achieved by studying the chemistry, photochemistry, and metabolism of BR and specially designed synthetic model compounds both in vitro and in vivo in animals ..
  4. Electron Transfer in Iron and Copper Proteins
    Jay R Winkler; Fiscal Year: 2010
    ..e., Fe-oxo Compounds I and II) are often invoked. Protein labeling and laser flash-quench photochemistry will be used to develop new insights into the reactive intermediates in heme-thiolate mono-oxygenases...
  5. HEME PROTEINS AND THEIR SYNTHETIC ANALOGS
    KENNETH SUSLICK; Fiscal Year: 1993
    ..Our exploration of the photochemistry of metalloporphyrins has created a new route to the formation of metal-oxo complexes...
  6. ULTRAVIOLET LIGHT INDUCED PHENOMENA IN BIOMEMBRANES
    IRENE KOCHEVAR; Fiscal Year: 1999
    b>Photochemistry in cellular membranes is responsible for initiating many responses of cells to ultraviolet and visible radiation with and without added photosensitizing molecules...
  7. THE PHOTOBIOLOGY OF VITAMIN D3
    Michael Holick; Fiscal Year: 1993
    The long-term objective of this research program is to develop a better understanding of (a) the photochemistry and photobiology of vitamin D3 that occurs in the skin when humans are exposed to sunlight and (b) what physiologic functions ..
  8. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    KENNETH KARLIN; Fiscal Year: 2007
    ..ligand Cu(l)-chelates, (2) study of key ligand- Cu2+(O2-) (superoxide) solvent hydrogen bonding and photochemistry, (3) a major effort to unravel mechanistic details of ligand-Cu2+(O2-) substrate reactivity involving hydrogen-..
  9. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    KENNETH KARLIN; Fiscal Year: 2009
    ..ligand Cu(l)-chelates, (2) study of key ligand- Cu2+(O2-) (superoxide) solvent hydrogen bonding and photochemistry, (3) a major effort to unravel mechanistic details of ligand-Cu2+(O2-) substrate reactivity involving hydrogen-..
  10. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    KENNETH KARLIN; Fiscal Year: 2009
    ..ligand Cu(l)-chelates, (2) study of key ligand- Cu2+(O2-) (superoxide) solvent hydrogen bonding and photochemistry, (3) a major effort to unravel mechanistic details of ligand-Cu2+(O2-) substrate reactivity involving hydrogen-..
  11. BIOINORGANIC COPPER COORDINATION CHEMISTRY
    Kenneth D Karlin; Fiscal Year: 2010
    ..ligand Cu(l)-chelates, (2) study of key ligand- Cu2+(O2-) (superoxide) solvent hydrogen bonding and photochemistry, (3) a major effort to unravel mechanistic details of ligand-Cu2+(O2-) substrate reactivity involving hydrogen-..
  12. Genomic Approaches to Neuronal Diversity and Plasticity
    Jingyue Ju; Fiscal Year: 2007
    ..The combined approach based on genomics, photochemistry, nanoscience and engineering, biochemistry, and neuroscience will be used to understand how neurons and ..
  13. ISOMERIC RETINOIDS, CAROTENOIDS, THEIR PROTEIN COMPLEXES
    Robert Liu; Fiscal Year: 2001
    ..Such knowledge is clearly important for prediction of photochemistry of polyenes, for synthetic applications and for a better understanding of the specific mode of reaction in ..
  14. Heme/Copper and Heme/Non-Heme Iron O2 and NO Reactivity
    KENNETH KARLIN; Fiscal Year: 2007
    ..of discrete heme/M compounds, their reactivity studies with O2 and NO, the coordination chemistry and the photochemistry of heme/M complexes, and the reductive O-O bond cleavage of heme/Cu/O2 adducts...
  15. Visibly Caged Bio-active Molecules and PDT
    Paul Jones; Fiscal Year: 2004
    ..To photoactivate thrombin and TPA, enzymes of ophthalmological relevance, using visible light. IV. To develop photochemistry capable of photoreleasing biologically active aldehydes and an in vitro demonstration of biological activity ..
  16. MOLECULAR MECHANISMS OF PHOTORECEPTOR FUNCTION
    BARRY KNOX; Fiscal Year: 2004
    ..The ability to introduce opsin mutants that have altered stability or photochemistry into rod cells will allow us to address several longstanding issues about rod photoreceptor behavior: ..
  17. Molecular characterization of mouse melanopsin and second messenger pathway.
    PHYLLIS ROBINSON; Fiscal Year: 2009
    ..This approach is designed to determine melanopsin's photochemistry, to elucidate the nature of the second messenger pathway activated by melanopsin, and to determine if there ..
  18. Molecular characterization of mouse melanopsin and second messenger pathway.
    Phyllis R Robinson; Fiscal Year: 2010
    ..This approach is designed to determine melanopsin's photochemistry, to elucidate the nature of the second messenger pathway activated by melanopsin, and to determine if there ..
  19. ULTRAFAST MULTIPHOTON LASER ACTIVATION SYSTEM
    WATT WEBB; Fiscal Year: 2001
    ..a select set of innovative biomedical and biotechnology research programs that are implemented by multiphoton photochemistry and photophysics...