electrochemistry

Summary

Summary: The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.

Articles from Journal RESEARCH

Top Publications

  1. ncbi Protein electrochemistry using aligned carbon nanotube arrays
    J Justin Gooding
    School of Chemical Sciences, The University of New South Wales, Sydney, NSW 2052, Australia
    J Am Chem Soc 125:9006-7. 2003
  2. ncbi Microbial fuel cells: methodology and technology
    Bruce E Logan
    Hydrogen Energy Center, 212 Sackett Building, Penn State University, University Park, Pennsylvania 16802, USA
    Environ Sci Technol 40:5181-92. 2006
  3. ncbi Pd-Pt bimetallic nanodendrites with high activity for oxygen reduction
    Byungkwon Lim
    Department of Biomedical Engineering, Washington University, St Louis, MO 63130, USA
    Science 324:1302-5. 2009
  4. ncbi Crystal structure of a mammalian voltage-dependent Shaker family K+ channel
    Stephen B Long
    Howard Hughes Medical Institute, Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Science 309:897-903. 2005
  5. ncbi Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution
    Y Zhou
    Department of Molecular Biophysics and Biochemistry, Yale University, 260 Whitney Avenue, New Haven, Connecticut 06520, USA
    Nature 414:43-8. 2001
  6. ncbi Exoelectrogenic bacteria that power microbial fuel cells
    Bruce E Logan
    Department of Civil and Environmental Engineering, Bruce E Logan is at the Hydrogen Energy Center, Penn State University, University Park, Pennsylvania 16802, USA
    Nat Rev Microbiol 7:375-81. 2009
  7. ncbi Electrochemical DNA sensors
    T Gregory Drummond
    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA
    Nat Biotechnol 21:1192-9. 2003
  8. ncbi Metal-air batteries: from oxygen reduction electrochemistry to cathode catalysts
    Fangyi Cheng
    Key Laboratory of Advanced Energy Materials Chemistry Ministry of Education, Chemistry College, Nankai University, Tianjin, 300071, People s Republic of China
    Chem Soc Rev 41:2172-92. 2012
  9. ncbi In situ formation of an oxygen-evolving catalyst in neutral water containing phosphate and Co2+
    Matthew W Kanan
    Department of Chemistry, 6 335, Massachusetts Institute of Technology, Cambridge, MA 02139 4307, USA
    Science 321:1072-5. 2008
  10. ncbi Electrospinning of polymeric nanofibers for tissue engineering applications: a review
    Quynh P Pham
    Department of Bioengineering, Rice University, Houston, Texas 77251 1892, USA
    Tissue Eng 12:1197-211. 2006

Detail Information

Articles from Journal RESEARCH1

Publications385 found, 100 shown here

  1. ncbi Protein electrochemistry using aligned carbon nanotube arrays
    J Justin Gooding
    School of Chemical Sciences, The University of New South Wales, Sydney, NSW 2052, Australia
    J Am Chem Soc 125:9006-7. 2003
    ..The efficiency of the electron transfer through the SWNTs is demonstrated by electrodes modified with tubes cut to different lengths having the same electron-transfer rate constant...
  2. ncbi Microbial fuel cells: methodology and technology
    Bruce E Logan
    Hydrogen Energy Center, 212 Sackett Building, Penn State University, University Park, Pennsylvania 16802, USA
    Environ Sci Technol 40:5181-92. 2006
    ..of MFCs requires knowledge of different scientific and engineering fields, ranging from microbiology and electrochemistry to materials and environmental engineering...
  3. ncbi Pd-Pt bimetallic nanodendrites with high activity for oxygen reduction
    Byungkwon Lim
    Department of Biomedical Engineering, Washington University, St Louis, MO 63130, USA
    Science 324:1302-5. 2009
    ..The Pd-Pt nanodendrites were two and a half times more active on the basis of equivalent Pt mass for the ORR than the state-of-the-art Pt/C catalyst and five times more active than the first-generation supportless Pt-black catalyst...
  4. ncbi Crystal structure of a mammalian voltage-dependent Shaker family K+ channel
    Stephen B Long
    Howard Hughes Medical Institute, Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Science 309:897-903. 2005
    ..Electrostatic properties of the side portals and positions of the T1 domain and beta subunit are consistent with electrophysiological studies of inactivation gating and with the possibility of K+ channel regulation by the beta subunit...
  5. ncbi Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution
    Y Zhou
    Department of Molecular Biophysics and Biochemistry, Yale University, 260 Whitney Avenue, New Haven, Connecticut 06520, USA
    Nature 414:43-8. 2001
    ..This structural change is crucial to the operation of the selectivity filter in the cellular context, where the K+ ion concentration near the selectivity filter varies in response to channel gating...
  6. ncbi Exoelectrogenic bacteria that power microbial fuel cells
    Bruce E Logan
    Department of Civil and Environmental Engineering, Bruce E Logan is at the Hydrogen Energy Center, Penn State University, University Park, Pennsylvania 16802, USA
    Nat Rev Microbiol 7:375-81. 2009
    ..To understand bacterial versatility in mechanisms used for current generation, this Progress article explores the underlying reasons for exocellular electron transfer, including cellular respiration and possible cell-cell communication...
  7. ncbi Electrochemical DNA sensors
    T Gregory Drummond
    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA
    Nat Biotechnol 21:1192-9. 2003
    b>Electrochemistry-based sensors offer sensitivity, selectivity and low cost for the detection of selected DNA sequences or mutated genes associated with human disease...
  8. ncbi Metal-air batteries: from oxygen reduction electrochemistry to cathode catalysts
    Fangyi Cheng
    Key Laboratory of Advanced Energy Materials Chemistry Ministry of Education, Chemistry College, Nankai University, Tianjin, 300071, People s Republic of China
    Chem Soc Rev 41:2172-92. 2012
    ..the fundamentals and recent advances related to the fields of metal-air batteries, with a focus on the electrochemistry and materials chemistry of air electrodes...
  9. ncbi In situ formation of an oxygen-evolving catalyst in neutral water containing phosphate and Co2+
    Matthew W Kanan
    Department of Chemistry, 6 335, Massachusetts Institute of Technology, Cambridge, MA 02139 4307, USA
    Science 321:1072-5. 2008
    ..This catalyst not only forms in situ from earth-abundant materials but also operates in neutral water under ambient conditions...
  10. ncbi Electrospinning of polymeric nanofibers for tissue engineering applications: a review
    Quynh P Pham
    Department of Bioengineering, Rice University, Houston, Texas 77251 1892, USA
    Tissue Eng 12:1197-211. 2006
    ....
  11. ncbi Sequence-specific detection of femtomolar DNA via a chronocoulometric DNA sensor (CDS): effects of nanoparticle-mediated amplification and nanoscale control of DNA assembly at electrodes
    Jiong Zhang
    Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
    J Am Chem Soc 128:8575-80. 2006
    ..In addition, this novel DNA sensor showed fairly good reproducibility, stability, and reusability...
  12. pmc Reversibility and efficiency in electrocatalytic energy conversion and lessons from enzymes
    Fraser A Armstrong
    Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford OX1 3QR, United Kingdom
    Proc Natl Acad Sci U S A 108:14049-54. 2011
    ..Enzymes thus set high standards for the catalysts of future energy technologies...
  13. ncbi Microelectrode arrays for electrochemistry: approaches to fabrication
    Xing Jiu Huang
    Department of Chemistry, Physical and Theoretical Chemistry Laboratory Oxford University, South Parks Road Oxford OX1 3QZ, UK
    Small 5:776-88. 2009
    ..These properties enable the use of microelectrode arrays and have captured much interest in the field of electrochemistry. Techniques for the fabrication of such arrays are reviewed...
  14. ncbi Stabilization of electrocatalytic metal nanoparticles at metal-metal oxide-graphene triple junction points
    Rong Kou
    Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    J Am Chem Soc 133:2541-7. 2011
    ..These new catalyst materials were tested for oxygen reduction for potential applications in polymer electrolyte membrane fuel cells, and they exhibited greatly enhanced stability and activity...
  15. ncbi Raising the cycling stability of aqueous lithium-ion batteries by eliminating oxygen in the electrolyte
    Jia Yan Luo
    Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Institute of New Energy, Fudan University, Shanghai 200433, China
    Nat Chem 2:760-5. 2010
    ....
  16. ncbi Binary and ternary doping of nitrogen, boron, and phosphorus into carbon for enhancing electrochemical oxygen reduction activity
    Chang Hyuck Choi
    Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 305 701, Republic of Korea
    ACS Nano 6:7084-91. 2012
    ....
  17. ncbi Cellobiose dehydrogenase: a versatile catalyst for electrochemical applications
    Roland Ludwig
    Department of Analytical Chemistry Biochemistry and Structural Biology, Lund University, P O Box 124, 22100 Lund, Sweden
    Chemphyschem 11:2674-97. 2010
    ..The results lead to valuable insights into the function of this cellulose-bound enzyme, but also form the basis of exciting applications in biosensors, biofuel cells and bioelectrocatalysis...
  18. ncbi Nitrogen-doped graphene and its application in electrochemical biosensing
    Ying Wang
    Department of Chemistry, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Tsinghua University, Beijing 100084, People s Republic of China
    ACS Nano 4:1790-8. 2010
    ..The N-doped graphene has further been used for glucose biosensing with concentrations as low as 0.01 mM in the presence of interferences...
  19. ncbi Electrochemical detection for paper-based microfluidics
    Wijitar Dungchai
    Sensor Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Patumwan, Bangkok, 10330, Thailand
    Anal Chem 81:5821-6. 2009
    ..This study shows the successful integration of paper-based microfluidics and electrochemical detection as an easy-to-use, inexpensive, and portable alternative for point of care monitoring...
  20. ncbi Glucose oxidase-graphene-chitosan modified electrode for direct electrochemistry and glucose sensing
    Xinhuang Kang
    Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Biosens Bioelectron 25:901-5. 2009
    Direct electrochemistry of a glucose oxidase (GOD)-graphene-chitosan nanocomposite was studied...
  21. pmc Single-step electronic detection of femtomolar DNA by target-induced strand displacement in an electrode-bound duplex
    Yi Xiao
    Department of Physics, Materials Department, Institute for Polymers and Organic Solids, University of California, Santa Barbara, CA 93106, USA
    Proc Natl Acad Sci U S A 103:16677-80. 2006
    ..Moreover, because sensor fabrication is straightforward, the approach appears to provide a ready alternative to the more cumbersome femtomolar electrochemical assays described to date...
  22. pmc Electrochemical interrogation of conformational changes as a reagentless method for the sequence-specific detection of DNA
    Chunhai Fan
    Institute for Polymers and Organic Solids, University of California, Santa Barbara, CA 93106, USA
    Proc Natl Acad Sci U S A 100:9134-7. 2003
    ..The E-DNA sensor thus offers the promise of convenient, reusable detection of picomolar DNA...
  23. ncbi Electrospun chitosan-based nanofibers and their cellular compatibility
    Narayan Bhattarai
    Department of Materials Science and Engineering, University of Washington, Seattle, WA 98195 2120, USA
    Biomaterials 26:6176-84. 2005
    ..This nanofibrous matrix is of particular interest in tissue engineering for controlled drug release and tissue remodeling...
  24. ncbi Applications of ionic liquids in electrochemical sensors
    Di Wei
    Process Chemistry Centre, c o Laboratory of Analytical Chemistry, Abo Akademi University, Biskopsgatan 8, FI 20500 Turku Abo, Finland
    Anal Chim Acta 607:126-35. 2008
    ..Besides a brief discussion of the properties of ILs and their general applications based on these properties, this review focuses on the application of ILs in electroanalytical sensors...
  25. ncbi Mesoscopic spatial designs of nano- and microfiber meshes for tissue-engineering matrix and scaffold based on newly devised multilayering and mixing electrospinning techniques
    Satoru Kidoaki
    Division of Biomedical Engineering, Graduate School of Medicine, Kyushu University, 3 1 1 Maidashi, Higashiku, Fukuoka City, Fukuoka 812 8582, Japan
    Biomaterials 26:37-46. 2005
    ....
  26. ncbi The mechanism of electroforming of metal oxide memristive switches
    J Joshua Yang
    Information and Quantum Systems Lab, Hewlett Packard Laboratories, Palo Alto, CA 94304, USA
    Nanotechnology 20:215201. 2009
    ..Better yet, electroforming problems can be largely eliminated by engineering the device structure to remove 'bulk' oxide effects in favor of interface-controlled electronic switching...
  27. ncbi Electrospinning of nano/micro scale poly(L-lactic acid) aligned fibers and their potential in neural tissue engineering
    F Yang
    Department of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117576
    Biomaterials 26:2603-10. 2005
    ..Based on the experimental results, the aligned nanofibrous PLLA scaffold could be used as a potential cell carrier in neural tissue engineering...
  28. ncbi Grafting of gelatin on electrospun poly(caprolactone) nanofibers to improve endothelial cell spreading and proliferation and to control cell Orientation
    Zuwei Ma
    Nanoscience and Nanotechnology Initiative, National University of Singapore
    Tissue Eng 11:1149-58. 2005
    ..The surface-modified PCL nanofibrous material is a potential candidate material in blood vessel tissue engineering...
  29. doi Building better batteries
    M Armand
    LRCS, CNRS UMR 6007, Universite de Picardie Jules Verne, Amiens, France
    Nature 451:652-7. 2008
  30. ncbi Double-codified gold nanolabels for enhanced immunoanalysis
    Adriano Ambrosi
    Nanobioelectronics and Biosensors Group, Institut Catala de Nanotecnologia, Barcelona, Catalonia, Spain
    Anal Chem 79:5232-40. 2007
    ..The developed label and method is versatile, offers enhanced performances, and can be easily extended to other protein detection schemes as well as in DNA analysis...
  31. ncbi Mechanical properties of single electrospun collagen type I fibers
    Lanti Yang
    Polymer Chemistry and Biomaterials, Faculty of Science and Technology and Institute for Biomedical Technology BMTI, University of Twente, P O Box 217, 7500 AE, Enschede, The Netherlands
    Biomaterials 29:955-62. 2008
    ..Cross-linking of the electrospun fibers with glutaraldehyde vapor increased the shear modulus of the fiber from approximately 30 to approximately 50 MPa at ambient conditions...
  32. ncbi Effect of fiber diameter on spreading, proliferation, and differentiation of osteoblastic cells on electrospun poly(lactic acid) substrates
    Anand S Badami
    Department of Chemical Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 0211, USA
    Biomaterials 27:596-606. 2006
    ..These studies show that topographical factors designed into biomaterial scaffolds can regulate spreading, orientation, and proliferation of osteoblastic cells...
  33. ncbi Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays
    Kelli Solly
    Department of Automated Biotechnology, Merck and Co, North Wales, PA, USA
    Assay Drug Dev Technol 2:363-72. 2004
    ..The conclusion is that the RT-CES system is a useful tool for label-free detection of certain cell-based parameters...
  34. ncbi Enzymatic biofuel cells for implantable and microscale devices
    Scott Calabrese Barton
    Department of Chemical Engineering, Columbia University, New York, New York 10027, USA
    Chem Rev 104:4867-86. 2004
  35. ncbi The application of nanofibrous scaffolds in neural tissue engineering
    Haoqing Cao
    Nanyang Technological University, Singapore
    Adv Drug Deliv Rev 61:1055-64. 2009
    ..Both fibrous scaffolds would enhance neurite extension and axon regrowth. These functional nanofibrous scaffolds can serve as powerful tools for neural tissue engineering...
  36. ncbi Linking bacterial metabolism to graphite cathodes: electrochemical insights into the H(2) -producing capability of Desulfovibrio sp
    Federico Aulenta
    Department of Chemistry, Sapienza University of Rome, P le Aldo Moro 5, 00185 Rome, Italy
    ChemSusChem 5:1080-5. 2012
    ..Remarkably, H(2) (at least up to 20 % v/v) was not found to significantly inhibit its own production...
  37. ncbi Direct electrochemistry of Phanerochaete chrysosporium cellobiose dehydrogenase covalently attached onto gold nanoparticle modified solid gold electrodes
    Hirotoshi Matsumura
    Department of Analytical Chemistry Biochemistry and Structural Biology, Lund University, SE 22100 Lund, Sweden
    Langmuir 28:10925-33. 2012
    ..The results provide insight into fundamental electrochemical properties of CDH covalently immobilized on gold electrodes and promote further applications of CDHs for biosensors, biofuel cells, and bioelectrocatalysis...
  38. ncbi Synthesis of nitrogen-doped graphene films for lithium battery application
    Arava Leela Mohana Reddy
    Department of Mechanical Engineering and Materials Science, Rice University, Houston, Texas 77005, United States
    ACS Nano 4:6337-42. 2010
    ..Direct growth of active electrode material on current collector substrates makes this a feasible and efficient process for integration into current battery manufacture technology...
  39. ncbi Structure and valency of a cobalt-phosphate water oxidation catalyst determined by in situ X-ray spectroscopy
    Matthew W Kanan
    Department of Chemistry, 6 335, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Am Chem Soc 132:13692-701. 2010
    ..Whereas cobaltates contain extended planes of CoO(6) octahedra, the Co-Pi clusters are of molecular dimensions...
  40. pmc Metallo-graphene nanocomposite electrocatalytic platform for the determination of toxic metal ions
    Chandre M Willemse
    Department of Chemistry, University of the Western Cape, Bellville, South Africa
    Sensors (Basel) 11:3970-87. 2011
    ..This was followed by real sample analysis...
  41. ncbi DNA-templated assembly and electrode attachment of a conducting silver wire
    E Braun
    Department of Physics, Technion Israel Institute of Technology, Haifa
    Nature 391:775-8. 1998
    ..The experiment confirms that the recognition capabilities of DNA can be exploited for the targeted attachment of functional wires...
  42. ncbi Surface engineering of electrospun polyethylene terephthalate (PET) nanofibers towards development of a new material for blood vessel engineering
    Zuwei Ma
    Nanoscience and Nanotechnology Initiative, National University of Singapore, 9 Engineering Drive 1, Singapore 117576, Singapore
    Biomaterials 26:2527-36. 2005
    ..The gelatin grafting method can obviously improve the spreading and proliferation of the ECs on the PET NFM, and moreover, can preserve the EC's phenotype...
  43. ncbi Direct electrochemistry of drug metabolizing human flavin-containing monooxygenase: electrochemical turnover of benzydamine and tamoxifen
    Sheila J Sadeghi
    Department of Human and Animal Biology, University of Turin, Italy
    J Am Chem Soc 132:458-9. 2010
    ..A structural model of the enzyme was generated to rationalize electrochemistry results. The turnover of the active enzyme was measured with two specific drugs: tamoxifen and benzydamine...
  44. pmc Interaction between amyloid-β peptide and heme probed by electrochemistry and atomic force microscopy
    Yanli Zhou
    Henan University Key Laboratory of Nanobiological Analytical Chemistry, Department of Chemistry and Chemical Engineering, Shangqiu normal University, Shangqiu 476000, China
    ACS Chem Neurosci 4:535-9. 2013
    ..According to results of the spectroscopic characterization, Arg5 was the key residue in making the heme-Aβ1-42 complex as a peroxidase...
  45. ncbi Biomolecule immobilization on electrode surfaces by entrapment or attachment to electrochemically polymerized films. A review
    S Cosnier
    Laboratoire d Electrochimie Organique et de Photochimie Redox, UMR CNRS 5630, Universite Joseph Fourier Grenoble 1, France
    Biosens Bioelectron 14:443-56. 1999
    ..Moreover, the attachment of biomolecules to biotinylated polymers through affinity interactions based on avidin-biotin bridge is presented...
  46. ncbi Thirty years of haemoglobin electrochemistry
    Frieder W Scheller
    University of Potsdam, Institute of Biochemistry and Biology, Department of Analytical Biochemistry, Karl Liebknecht Strasse 24 25, Bldg 25, D 14476 Golm, Germany
    Adv Colloid Interface Sci 116:111-20. 2005
    ..On the other hand, entrapment of the protein within layers of polyelectrolytes, lipids, nanoparticles of clay or gold leads to a fast heterogeneous electron exchange of the partially denatured Hb...
  47. ncbi Conducting polymers in electronic chemical sensors
    Jiri Janata
    School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332 0400, USA
    Nat Mater 2:19-24. 2003
    ..Our aim here is to discuss the usability of conducting polymers in both types of electronic applications in light of these two parameters...
  48. ncbi Luminescent cyclometalated iridium(III) polypyridine indole complexes--synthesis, photophysics, electrochemistry, protein-binding properties, cytotoxicity, and cellular uptake
    Jason Shing Yip Lau
    Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, People s Republic of China
    Inorg Chem 48:708-18. 2009
    ....
  49. ncbi Simultaneous determination of L-ascorbic acid, dopamine and uric acid with gold nanoparticles-β-cyclodextrin-graphene-modified electrode by square wave voltammetry
    Xianqing Tian
    College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu 610064, PR China
    Talanta 93:79-85. 2012
    ..Our work provides a simple, convenient and green route to synthesize AuNPs on Gra which is potentially useful in electroanalysis...
  50. ncbi High current generation coupled to caustic production using a lamellar bioelectrochemical system
    Korneel Rabaey
    Advanced Water Management Centre, The University of Queensland, Brisbane, Queensland 4072, Australia
    Environ Sci Technol 44:4315-21. 2010
    ..This study is the first to demonstrate effective production of caustic at liter scale, using BESs both in laboratory and field conditions. It also shows that input of power can easily be justified by product value...
  51. ncbi Controlling analyte electrochemistry in an electrospray ion source with a three-electrode emitter cell
    Gary J Van Berkel
    Organic and Biological Mass Spectrometry Group, Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831 6131, USA
    Anal Chem 76:1493-9. 2004
    The inherent electrochemistry occurring at the emitter electrode of an electrospray ion source was effectively controlled by incorporating a three-electrode controlled-potential electrochemical cell into the controlled-current ..
  52. ncbi Morphology-dependent electrochemistry and electrocatalytical activity of cytochrome c
    Haiqing Liu
    Department of Chemistry, Tongji University, Shanghai, PR China
    Langmuir 23:9487-94. 2007
    The morphology-dependent electrochemistry and electrocatalytical activity of cytochrome c (cyt. c) were investigated at pyramidal, rodlike, and spherical gold nanostructures directly electrodeposited onto sputtered gold surfaces...
  53. ncbi Membrane-based electrochemical nanobiosensor for Escherichia coli detection and analysis of cells viability
    Ming Soon Cheng
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore
    Environ Sci Technol 45:6453-9. 2011
    ....
  54. ncbi Review: Carbon nanotube based electrochemical sensors for biomolecules
    Christopher B Jacobs
    Dept of Chemistry, University of Virginia, PO Box 400319, Charlottesville, VA 22904, United States
    Anal Chim Acta 662:105-27. 2010
    ..Future challenges for the field include miniaturizing sensors, developing methods to use only a specific nanotube allotrope, and simplifying manufacturing...
  55. ncbi Luminescent cyclometalated iridium(III) polypyridine di-2-picolylamine complexes: synthesis, photophysics, electrochemistry, cation binding, cellular internalization, and cytotoxic activity
    Pui Kei Lee
    Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, People s Republic of China
    Inorg Chem 50:8570-9. 2011
    ....
  56. ncbi Comparison between electrochemistry/mass spectrometry and cytochrome P450 catalyzed oxidation reactions
    Ulrik Jurva
    Centre for Pharmacy, University of Groningen, The Netherlands
    Rapid Commun Mass Spectrom 17:800-10. 2003
    The extent to which electrochemistry on-line with electrospray mass spectrometry can be used to mimic cytochrome P450 catalyzed oxidations has been investigated...
  57. ncbi Membrane-based electrochemical nanobiosensor for the detection of virus
    Binh T T Nguyen
    Department of Chemistry, Faculty of Science, Yong Loo Lin School of Medicine, 3 Science Drive 3, National University of Singapore, Singapore 117543
    Anal Chem 81:7226-34. 2009
    ....
  58. pmc Cocaine cues drive opposing context-dependent shifts in reward processing and emotional state
    Robert A Wheeler
    Department of Psychology, University of North Carolina, Chapel Hill, USA
    Biol Psychiatry 69:1067-74. 2011
    ..To test this, we examined dopamine release when cues signaled delayed cocaine delivery versus imminent cocaine self-administration...
  59. ncbi Electrochemistry and biosensing of glucose oxidase based on mesoporous carbons with different spatially ordered dimensions
    Chunping You
    Department of Chemistry and Institutes of Biomedical Sciences and Novel Materials, Fudan University, Shanghai 200433, PR China
    Talanta 78:705-10. 2009
    A strategy of protein entrapment within mesoporous carbon matrices is demonstrated to probe the electrochemistry of glucose oxidase...
  60. pmc Fast DNA sequencing via transverse electronic transport
    Johan Lagerqvist
    Department of Physics, University of California, San Diego, La Jolla, California 92093 0319, USA
    Nano Lett 6:779-82. 2006
    ..The practical implementation of our approach would represent a substantial advancement in our ability to study, predict, and cure diseases from the perspective of the genetic makeup of each individual...
  61. ncbi Layer-by-Layer self-assembled acetylcholinesterase/PAMAM-Au on CNTs modified electrode for sensing pesticides
    Yunhe Qu
    Department of Chemistry, East China Normal University, Shanghai, PR China
    Bioelectrochemistry 77:139-44. 2010
    ..8x10(-9)M to 0.9x10(-7)M was exhibited with a detection limit of 4.0x10(-9)M. The biosensor showed high sensitivity, good stability and reproducibility with promising application...
  62. ncbi Direct electrochemistry of horseradish peroxidase immobilized on a monolayer modified nanowire array electrode
    Ju Xu
    Tyndall National Institute, University College Cork, Cork, Ireland
    Biosens Bioelectron 25:1313-8. 2010
    ..The ordered 3D gold nanowire array with high conductivity, excellent electron transfer capability and good biocompatibility proved promising for fabricating sensitive, selective, stable and mediator-free enzymatic biosensors...
  63. ncbi Action of antimicrobial peptides: two-state model
    H W Huang
    Department of Physics, Rice University, Houston, Texas 77251, USA
    Biochemistry 39:8347-52. 2000
    ....
  64. pmc Preferential enhancement of dopamine transmission within the nucleus accumbens shell by cocaine is attributable to a direct increase in phasic dopamine release events
    Brandon J Aragona
    Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 3290, USA
    J Neurosci 28:8821-31. 2008
    ..Together, these results demonstrate that cocaine administration results in a temporally and regionally specific increase in phasic dopamine release that is significantly regulated by dopamine autoreceptors...
  65. ncbi Direct electrochemistry of horseradish peroxidase based on biocompatible carboxymethyl chitosan-gold nanoparticle nanocomposite
    Qin Xu
    School of Chemistry and Chemical Engineering, Laboratory of Life Analytical Chemistry, Nanjing University, Nanjing 210093, PR China
    Biosens Bioelectron 22:768-73. 2006
    ..0 x 10(-6) to 1.4 x 10(-3)M, and a low detection limit of 4.01 x 10(-7)M. The apparent Michaelis-Menten constant (K(M)(app)) for the biosensor was 5.7 x 10(-4)M. Good stability and sensitivity were assessed for the biosensor...
  66. ncbi Long-term multiple color imaging of live cells using quantum dot bioconjugates
    Jyoti K Jaiswal
    The Rockefeller University, Box 304, 1230 York Avenue, New York, NY 10021, USA
    Nat Biotechnol 21:47-51. 2003
    ..The cells remained stably labeled for over a week as they grew and developed. These approaches should permit the simultaneous study of multiple cells over long periods of time as they proceed through growth and development...
  67. ncbi Immobilization of peroxidase glycoprotein on gold electrodes modified with mixed epoxy-boronic Acid monolayers
    Jose M Abad
    Instituto de Catálisis y Petroleoquímica and Instituto de Ciencia de Materiales de Madrid, CSIC, Campus Universidad Autonoma de Madrid, Spain
    J Am Chem Soc 124:12845-53. 2002
    ..These epoxy-boronate functional monolayers are versatile, stable interfaces, ready to incorporate glycoproteins by incubation under mild conditions...
  68. pmc Microfabricated microbial fuel cell arrays reveal electrochemically active microbes
    Huijie Hou
    Department of Electrical and Computer Engineering, Texas A and M University, College Station, TX, USA
    PLoS ONE 4:e6570. 2009
    ..MR-7, and displayed 2.3-fold higher power output than the S. oneidensis MR-1 reference strain. Therefore, the utility of the MFC array was demonstrated...
  69. ncbi Graphene-based materials in electrochemistry
    Da Chen
    Department of Chemistry, Key Lab of Bioorganic Phosphorus Chemistry and Chemical Biology, Tsinghua University, Beijing 100084, China
    Chem Soc Rev 39:3157-80. 2010
    ..we will describe recent advances in the development of graphene-based materials from the standpoint of electrochemistry. To begin with, electron transfer properties of graphene will be discussed, involving its unusual electronic ..
  70. ncbi Analysis of exocytotic events recorded by amperometry
    Eugene V Mosharov
    Department of Neurology, Black Building 305, 650 W 168th Street, Columbia University, New York, New York 10032, USA
    Nat Methods 2:651-8. 2005
    ..The purpose of this review is to provide practical guidelines for performing amperometric recordings of exocytotic activity and interpreting the results based on shape characteristics of individual release events...
  71. ncbi Electroanalytical properties of a novel biosensor modified with zirconium alcoxide porous gels for the detection of acetaminophen
    Veronica Sima
    Analytical Chemistry and Instrumental Analysis Department, Faculty of Pharmacy, Iuliu Hatieganu University of Medicine and Pharmacy, 4 Pasteur Street, 400 349 Cluj Napoca, Romania
    J Pharm Biomed Anal 48:1195-200. 2008
    ..96 x 10(-5)M and 2.55 x 10(-4)M and a limit of detection of 1.17 x 10(-7)M. The proposed biosensor shows long term stability and good reproducibility...
  72. ncbi How cytochromes with different folds control heme redox potentials
    Junjun Mao
    Physics Department J 419, City College of New York, 138th Street and Convent Avenue, New York, New York 10031, USA
    Biochemistry 42:9829-40. 2003
    ....
  73. ncbi Breaking the barrier to fast electron transfer
    Soren Demin
    Institute of Biotechnology, Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QT, United Kingdom
    Bioelectrochemistry 76:19-27. 2009
    ....
  74. ncbi SOAS: a free program to analyze electrochemical data and other one-dimensional signals
    Vincent Fourmond
    Unite de Bioenergetique et Ingenierie des Proteines, UPR 9036, CNRS, 31 Chemin Joseph Aiguier, F 13402 Marseille Cedex 20, France
    Bioelectrochemistry 76:141-7. 2009
    ..This free program is available by download from the Internet, and can be installed on computers running any flavor of Unix or Linux, most easily on MacOS X...
  75. ncbi Fenton chemistry and iron chelation under physiologically relevant conditions: Electrochemistry and kinetics
    Martin Merkofer
    Laboratorium für Anorganische Chemie, Departement Chemie und Angewandte Biowissenschaften, ETH Zurich, CH 8093 Zurich, Switzerland
    Chem Res Toxicol 19:1263-9. 2006
    ..Although iron(II) is oxidized by hydrogen peroxide, the thus-formed Fe(III)(CP20)(3) complex cannot be reduced by ascorbate. Therefore, the tight binding of iron(III) by this class of chelators prevents redox cycling...
  76. ncbi Electrospun poly(epsilon-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration
    Quynh P Pham
    Department of Bioengineering, Rice University, MS 142, P O Box 1892, Houston, Texas 77251 1892, USA
    Biomacromolecules 7:2796-805. 2006
    ..The scaffold design presented in this study allows for cellular infiltration into the scaffolds while at the same time providing nanofibers as a physical mimicry of extracellular matrix...
  77. ncbi Materials science. Playing nature's game with artificial muscles
    Ray H Baughman
    NanoTech Institute and Department of Chemistry, University of Texas at Dallas, Richardson, TX 75083, USA Ray
    Science 308:63-5. 2005
  78. ncbi Glutaraldehyde activated eggshell membrane for immobilization of tyrosinase from Amorphophallus companulatus: application in construction of electrochemical biosensor for dopamine
    Sanket Tembe
    Department of Chemistry, University of Pune, Ganeshkhind, Pune 411007, India
    Anal Chim Acta 612:212-7. 2008
    ..19 V versus Ag/AgCl (3M KCl). Linearity was observed within the range of 50-250 microM with a detection limit of 25 microM...
  79. ncbi New directions in medical biosensors employing poly(3,4-ethylenedioxy thiophene) derivative-based electrodes
    Noemi Rozlosnik
    Department of Micro and Nanotechnology, Technical University of Denmark, Ørsteds Plads, Bygning 345e, DK 2800, Kgs Lyngby, Denmark
    Anal Bioanal Chem 395:637-45. 2009
    ..This review paper summarizes newly developed methods associated with the application of PEDOT to diagnostic sensing...
  80. ncbi Photoelectric properties of a detector based on dried bacteriorhodopsin film
    Wei Wei Wang
    Department of Mechanical and Materials Engineering, Faculty of Engineering, The University of Western Ontario, London, Ontario, Canada N6A 5B9
    Biosens Bioelectron 21:1309-19. 2006
    ..Experimental observations and a predictive model both support the notion that dried bR film can be used in simple highly sensitive photo-detector designs...
  81. ncbi Electrochemical interrogations of the Mtr cytochromes from Shewanella: opening a potential window
    Mackenzie Firer-Sherwood
    Department of Chemistry, Boston University, 590 Commonwealth Ave, Boston, MA 02215, USA
    J Biol Inorg Chem 13:849-54. 2008
    ..These data are taken together to suggest a model of electron transport where a wide window of potential allows for charge transfer from the cellular interior to the exterior to support bioenergetics...
  82. ncbi In vitro degradation and release profiles for electrospun polymeric fibers containing paracetanol
    Hongsen Peng
    Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, PR China
    Colloids Surf B Biointerfaces 66:206-12. 2008
    ..The result showed that the drug burst release behaviour was mainly related with the drug-polymer compatibility and the followed sustained release phase depended on polymer degradation...
  83. ncbi Protein capture in silica nanotube membrane 3-D microwell arrays
    Myungchan Kang
    Department of Chemistry and Center for Research at the Bio Nano Interface, University of Florida, Gainesville, Florida 32611 7200, USA
    Anal Chem 77:6243-9. 2005
    ..The Ag surrounding the microwells shows very low background fluorescence, thus improving the signal-background ratio obtained from these arrays...
  84. ncbi Label- and marker-free gene detection based on hybridization-induced conformational flexibility changes in a ferrocene-PNA conjugate probe
    Hiroshi Aoki
    National Institute of Advanced Industrial Science and Technology AIST, 16 1 Onogawa, Tsukuba, Ibaraki 305 8569, Japan
    Analyst 132:784-91. 2007
    ..Moreover, the sensor electrode was able repeatedly to detect the target DNA by the process of regeneration and could discriminate a mismatched DNA...
  85. ncbi Hydrothermally shrunk alumina nanopores and their application to DNA sensing
    Pavel Takmakov
    Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, USA
    Analyst 131:1248-53. 2006
    ..Hybridization of target DNA with a complementary ssDNA covalently immobilized inside the nanopores causes an increase in impedance by more than 50% while a noncomplementary ssDNA has no measurable effect...
  86. ncbi Trace analysis of an oligonucleotide with a specific sequence using PNA-based ion-channel sensors
    Hiroshi Aoki
    Department of Chemistry, School of Science, The University of Tokyo, Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Analyst 128:681-5. 2003
    ..Using a 13-mer PNA probe for this sensing mode, we achieved the detection of the oligonucleotide at a femtomolar (approximately 10-15 M) level, improved by five orders of magnitude than the previously used 10-mer PNA probe...
  87. ncbi Enhanced electrochemiluminescence of CdSe quantum dots composited with CNTs and PDDA for sensitive immunoassay
    Guifen Jie
    Key Laboratory of Analytical Chemistry for Life Science Ministry of Education of China, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, PR China
    Biosens Bioelectron 24:3352-8. 2009
    ..This work opened the new avenues for applying QDs ECL in highly sensitive bioassays...
  88. ncbi An efficient bicomponent TiO2/SnO2 nanofiber photocatalyst fabricated by electrospinning with a side-by-side dual spinneret method
    Zhaoyang Liu
    School of Civil and Environmental Engineering, Nanyang Technological University, Singapore
    Nano Lett 7:1081-5. 2007
    ..We believe that this versatile approach can be extended to fabricate other novel high-efficiency bicomponent photocatalysts...
  89. ncbi Towards biosensors based on conducting polymer nanowires
    Sagar B Tolani
    Department of Chemistry, Missouri State University, Springfield, MO 65897, USA
    Anal Bioanal Chem 393:1225-31. 2009
    ..Therefore, the technology has the potential to positively impact broad analytical applications in the biomedical, environmental and other sectors...
  90. ncbi Electrocatalytic oxidation of dopamine at an ionic liquid modified carbon paste electrode and its analytical application
    Wei Sun
    College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, China
    Anal Bioanal Chem 389:1283-91. 2007
    ..The IL-CPE fabricated was sensitive, selective and showed good ability to distinguish the coexisting ascorbic acid and uric acid...
  91. ncbi Nanogap detector inside nanofluidic channel for fast real-time label-free DNA analysis
    Xiaogan Liang
    NanoStructure Laboratory, Department of Electrical Engineering, Princeton University, Princeton, New Jersey 08544, USA
    Nano Lett 8:1472-6. 2008
    ..We have observed electrical signals caused by 1.1 kilobase-pair (kbp) double-stranded (ds)-DNA passing through the gap in the nanogap detectors with a gap equal to or less than 13 nm...
  92. ncbi A portable potentiostat for the bilirubin-specific sensor prepared from molecular imprinting
    Chun Yueh Huang
    Institute of Communication Engineering, National University of Tainan, Taiwan, ROC
    Biosens Bioelectron 22:1694-9. 2007
    ..The self-assembled potentiostat thus demonstrated its ability in precise detection of bilirubin from an electrode layered with the imprinted polymer film...
  93. ncbi Intraperitoneal zinc administration increases extracellular zinc in the rat prefrontal cortex
    W Opoka
    Laboratory of Trace Elements Neurobiology, Department of Neurobiology, Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland
    J Physiol Pharmacol 59:477-87. 2008
    ..The results indicate zinc-induced fast brain penetration and may explain its rapid pharmacological effects...
  94. ncbi A tris(2,2'-bipyridyl)cobalt(III)-bovine serum albumin composite membrane for biosensors
    Ying Zhuo
    Key Laboratory of Analytical Chemistry Chongqing, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China
    Biomaterials 27:5420-9. 2006
    ..50-80.00 ng/mL with a limit of detection of 0.14 ng/mL, as well as good stability and long-term life...
  95. ncbi Voltammetric studies on the HIV-1 inhibitory drug Efavirenz: the interaction between dsDNA and drug using electrochemical DNA biosensor and adsorptive stripping voltammetric determination on disposable pencil graphite electrode
    Burcu Dogan-Topal
    Ankara University, Faculty of Pharmacy, Department of Analytical Chemistry, 06100, Tandogan, Ankara, Turkey
    Biosens Bioelectron 24:2358-64. 2009
    ..Under these conditions, the current showed a linear dependence with concentration in the range between 0.018 and 2.56 ppm. Both determination methods were fully validated and applied for the analysis of EFV pharmaceutical dosage form...
  96. ncbi The flavoprotein subcomplex of complex I (NADH:ubiquinone oxidoreductase) from bovine heart mitochondria: insights into the mechanisms of NADH oxidation and NAD+ reduction from protein film voltammetry
    Chérise D Barker
    Medical Research Council Dunn Human Nutrition Unit, Wellcome Trust MRC Building, Hills Road, Cambridge CB2 2XY, UK
    Biochemistry 46:3454-64. 2007
    ..Two possible models reproduce the observed catalytic waveshapes: one describing an effect from reducing the proximal [2Fe-2S] cluster and the other the enhanced catalytic ability of the semiflavin state...
  97. pmc Patterning of polymer nanofiber meshes by electrospinning for biomedical applications
    Nuno M Neves
    Department of Polymer Engineering, University of Minho, Campus de Azurem, 4800 058 Guimaraes, Portugal
    Int J Nanomedicine 2:433-48. 2007
    ..The present study will evaluate cell adhesion sensitivity to the patterns generated and the effect of those patterns on the tensile properties of the fiber meshes...
  98. ncbi Improved selectivity and stability of glucose biosensor based on in situ electropolymerized polyaniline-polyacrylonitrile composite film
    Huaiguo Xue
    School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China
    Biosens Bioelectron 20:2330-4. 2005
    ..Blood glucose determinations agreed well with standard hospital laboratory analysis. The construction and operational parameters of the biosensor were also optimized...
  99. ncbi Direct electrochemistry of immobilized human cytochrome P450 2E1
    Andrea Fantuzzi
    Department of Biological Sciences, Imperial College, London, UK
    J Am Chem Soc 126:5040-1. 2004
    ..The turnover of the active enzyme was measured with the P450 2E1 specific substrate p-nitrophenol, resulting in a KM of 130 +/- 3 muM and the formation of 2.2 muM of the p-nitrocatechol product upon application of a -300 mV bias...
  100. ncbi Cyclic voltammetry and voltabsorptometry studies of redox proteins immobilised on nanocrystalline tin dioxide electrodes
    Yeni Astuti
    Department of Chemistry, Imperial College London, Exhibition Road, South Kensington, London SW7 2AZ, UK
    Bioelectrochemistry 63:55-9. 2004
    ..We demonstrate that cyclic voltabsorptometry allows the unambiguous and background free observation of redox reactions for both systems studied...
  101. ncbi Microelectrodes for the measurement of catecholamines in biological systems
    P S Cahill
    Department of Chemistry, University of North Carolina, Chapel Hill 27599 3290, USA
    Anal Chem 68:3180-6. 1996
    ..Also, high-pass filtering discriminated against ascorbic acid, DOPAC, and acidic pH changes, three common interferences in vivo...

Research Grants62

  1. The Electrochemistry of Diheme Cytochrome c Peroxidases
    Sean J Elliott; Fiscal Year: 2010
    ..Further, our study of triheme CCPs will elucidate the CCP machinery which is unique to pathogens such as Salmonella enterica and Yersinia pestis, providing new insights into their biochemical pathways. ..
  2. Oxidative Stress and Glutamate Excitotoxicity on Aged Dopaminergic Neruons
    Heather A Boger; Fiscal Year: 2010
    ..Year 1-2) of the award from a team of collaborating mentors that include training in molecular biology, electrochemistry, production of nanoparticles (microspheres), and statistics...
  3. Oxidative Stress and Glutamate Excitotoxicity on Aged Dopaminergic Neruons
    Heather A Boger; Fiscal Year: 2013
    ..Year 1-2) of the award from a team of collaborating mentors that include training in molecular biology, electrochemistry, production of nanoparticles (microspheres), and statistics...
  4. The Role of Adenosine in Ketogenic Diet Therapy
    Susan A Masino; Fiscal Year: 2013
    ..on synaptic transmission and neuronal excitability will be quantified using detailed electrophysiology and electrochemistry (Aim 2)...
  5. Neurobiological Investigation of Decision Making in Rats
    Regina M Carelli; Fiscal Year: 2013
    ..Likewise, electrochemistry studies employing fast scan cyclic voltammetry (FSCV) have shown that DA release in the NAc encodes similar ..
  6. ELECTROANALYSIS OF NEUROTRANSMITTERS AND MODULATORS
    ROBERT MARK WIGHTMAN; Fiscal Year: 2013
    ..The research plan is based upon our prior development of an electrochemistry-based method to monitor dopamine in behaving animals...
  7. Microchip devices to assay quantal exocytosis
    KEVIN GILLIS; Fiscal Year: 2009
    ..with expertise is biomedical, electrical and mechanical engineering, materials science, physics, electrochemistry, physiology and biophysics...
  8. DNA Charge Transport Chemistry &Biology
    Jacqueline K Barton; Fiscal Year: 2012
    ..CT will be probed using DNA electrochemistry, EPR, transient absorption spectroscopy and AFM...
  9. Selection-driven plant metabolites for treatment of CNS diseases
    John M Littleton; Fiscal Year: 2013
    ..The most active compounds will then be tested for functional effects on the DAT in rat brain in vivo using electrochemistry. In parallel studies, the mutant clonal cultures which are overproducing active metabolites to the greatest ..
  10. Regulation of Cytosolic Dopamine by Ca2+ in Ventral Midbrain Neurons
    Eugene V Mosharov; Fiscal Year: 2010
    ..catecholamine homeostasis between different neuronal populations, we recently developed intracellular patch electrochemistry (IPE), a technique that directly measures cellular concentrations of cytosolic catecholamines...
  11. Probing the mechanism and diversity of multi-electron redox reactions in sulfite
    EVAN THOMAS JUDD; Fiscal Year: 2013
    ..In addition, the training program offers training in the highly specialized area of protein electrochemistry, offering training in techniques such as Protein Film Voltammetry and potentiometry...
  12. Improved Batteries for Implantable Cardiac Defibrillators
    Kenneth J Takeuchi; Fiscal Year: 2012
    ..The proposed activity involves the synthesis, characterization and electrochemistry of a new family of materials, MM'POs...
  13. Low-Coordinate Synthetic Models for Nitrogenase Activity
    Patrick L Holland; Fiscal Year: 2013
    ..Crystallography, kinetic studies, electrochemistry, and reactivity will be used to elucidate the atomic-level detail of the elementary steps of small-molecule ..
  14. Mechanism of Action of Deep Brain Stimulation
    Kendall H Lee; Fiscal Year: 2012
    ..This program will promote the command of electrophysiology, electrochemistry, brain imaging and stereotactic and functional neurosurgery. Dr...
  15. CATECHOLAMINES AND SEROTONIN IN BLOOD PRESSURE CONTROL
    Curt Freed; Fiscal Year: 1991
    ..With the new technique of in vivo electrochemistry, we have been able to follow the time course of catechol and 5-HIAA concentrations continuously during drug- ..
  16. 2012 Bioanalytical Sensors Gordon Research Conference and Gordon Research Seminar
    Steven Allan Soper; Fiscal Year: 2012
    ..molecular/cellular/protein biology, nanotechnology, microtechnology, optical engineering, and electrochemistry to name a few...
  17. WINCS and DBS
    Kendall H Lee; Fiscal Year: 2013
    ..We believe that the simultaneous combination of fMRI and electrochemistry offer a new and exciting approach that provides complementary anatomical mapping and neurochemical monitoring ..
  18. 2010 Bioanalytical Sensors Gordon Research Conference
    Antje J Baeumner; Fiscal Year: 2010
    ..design/recognition, molecular/cellular/protein biology, nano/microtechnology, optical engineering, electrochemistry to name a few...
  19. Quantifying Axon Growth in Complex Environments
    Diane Hoffman Kim; Fiscal Year: 2010
    ..the Principal Investigator in neuronal development, regeneration, and biomaterials and the Co-Investigator in electrochemistry, microfabrication, and surface characterization, to fabricate a platform capable of delivering precise ..
  20. New Mechanisms for Alkene Functionalization Using Redox Active Ligands
    ALISON NICOLE CAMPBELL; Fiscal Year: 2010
    ..To achieve these goals, palladium complexes bound to redox-active ligands will be prepared and studied by electrochemistry to gain an understanding of their oxidation and reduction properties...
  21. Synthesis of CO Dehydrogenase Model Complexes for Catalytic Reductions of CO2
    DAVID CHARLES LACY; Fiscal Year: 2013
    ..Additionally, he is knowledgeable in the field of electrochemistry and electrocatalytic methods...
  22. Engineered Self-Assembling Fvs for Piezoimmunosensors
    Xiangqun Zeng; Fiscal Year: 2009
    ..Four bioengineering methods will be used to create an Fv-SAM that possesses the necessary attributes. Electrochemistry, network impedance analysis, and Atomic Force Microscope (AFM) will be used in parallel to characterize the ..
  23. Nitrogen Oxides and Heme
    GEORGE RICHTER ADDO; Fiscal Year: 2007
    ..liganded heme model compounds with NO ligands and characterize them by spectroscopy (IR, EPR, rR, UV-vis), electrochemistry, and crystallography...
  24. COORDINATION CHEMISTRY OF VANADIUM IN BIOLOGY SYSTEM
    CARL CARRANO; Fiscal Year: 1992
    ..will include UV-vis spectro-photometry, NMR (1H, 13C and 51V as appropriate), EPR, magnetic measurements, electrochemistry and, when appropriate, single crystal X-ray diffraction...
  25. MARIJUANA & DOPAMINE/ENKEPHALIN BRAIN REWARD SYSTEMS
    ELIOT GARDNER; Fiscal Year: 1992
    ..on DA release, in forebrain DA loci supporting direct brain reward, as measured by both in vivo voltammetric electrochemistry and in vivo intracranial microdialysis; and (3) extend our studies of the interaction of delta9-THC and ..
  26. Sequencing DNA by transverse electrical measurements in Nanochannels
    Robert Riehn; Fiscal Year: 2009
    ..We will investigate the mechanism by which the signal arises, and will in particular examine tunneling, electrochemistry, or polarization of counterions as possible candidates...
  27. Redox incuced Metal Transfer Reaction of Metalloproteins
    Feimeng Zhou; Fiscal Year: 2001
    ..the metal-transfer processes induced (modulated) by the redox reactions of immobilized MT molecules using electrochemistry combined on-line with atomic spectroscopic techniques...
  28. ANALYSIS OF ENDORPHINS BY LC-ELECTROCHEMISTRY
    Norman Reynolds; Fiscal Year: 1990
    ..This LC-EC assays will be especially useful for those studies which require a detailed analysis of endorphin content...
  29. Analytical Techniques for Exocytosis
    Andrew Ewing; Fiscal Year: 2009
    ..by fluorescence and to investigate the mechanism of membrane trafficking to and from vesicles;and 4) to use electrochemistry and fluorescence to examine and develop models of transmitter release via the fusion pore prior to full ..
  30. HEPATIC MICROSOMAL DRUG OXIDATION
    Ronald Estabrook; Fiscal Year: 2000
    ..of the flavoprotein, NADPH- P450 reductase to the heme-domain of the hemeprotein, P450 using the technique of electrochemistry recently developed int his laboratory...
  31. DEVELOPMENT OF SELECTIVE NICOTINIC RECEPTOR ANTAGONISTS
    Linda Dwoskin; Fiscal Year: 2003
    ..fellow and the work time and travel funds necessary to learn new techniques, including in vivo and in vitro electrochemistry from collaborative investigators at the University of Kentucky and Indiana University...
  32. IRON DEPOSITION AND MOBILIZATION IN FERRITIN
    NORMAN CHASTEEN; Fiscal Year: 2001
    ..The mechanisms will be investigated through a combination of EPR, ENDOR, ESEEM and Mossbauer spectroscopy, electrochemistry and kinetic studies of horse and sheep spleen ferritins as well as recombinant H and L human liver ferritins ..
  33. NEUROBEHAVIORAL PLASTICITY AFTER DOPAMINE SYSTEM DAMAGE
    Jay Schneider; Fiscal Year: 2000
    ..techniques (in situ hybridization histochemistry, immunohistochemistry, ligand binding, and in vivo electrochemistry) to study the DA transporter and the presynaptic DA system...
  34. EFFECTS OF PHENCYCLIDINE ON NEURONAL FUNCTION
    Robert Freedman; Fiscal Year: 1991
    ..will be studied using extracellular electrophysiological recordings from single neurons and using in vivo electrochemistry to measure catecholamine transmitter release in vivo...
  35. MODELS OF THE CYTOCHROMES
    Frances Walker; Fiscal Year: 2005
    ..the (dxz,dyz)4 (dxy) ground state will be investigated by X-ray crystallography, magnetic spectroscopies and electrochemistry to determine whether they have this ground state, and if so, whether they have different redox reactivity ..
  36. REDOX REACTIONS OF IRON PORPHYRINS
    KARL KADISH; Fiscal Year: 1991
    ..Extensive use will be made of variable temperature electrochemistry, thin- layer spectroelectrochemistry, and combined ESR/electrochemistry techniques, three techniques ..
  37. STICS: Surface-Tethered Iterative Carbohydrate Synthesis
    Keith Stine; Fiscal Year: 2007
    ..The porous gold films will be created on titanium foil, and then characterized using electron microscopy and electrochemistry. The gold surfaces will then be modified with self-assembled monolayers of tri-thiolated derivatives designed ..
  38. Dynamic control of dopamine release in cocaine abuse
    Paul Phillips; Fiscal Year: 2006
    ..Realtime electrochemistry, that samples extracellular dopamine with subsecond time resolution, provides a unique opportunity to study ..
  39. ELECTROCHEMISTRY-EPR OF BIOLOGICAL ELECTRON TRANSFER
    Ralph Adams; Fiscal Year: 1992
    ..Some recently developed micro chemical probes will be used to develop rapid, sensitive sampling techniques for brain tissue which should be amenable to automation. Such systems could have widespread use in both brain and chemical assays...
  40. MOUNTAIN-PLAINS RTC FOR CHEMOSENSORY DISORDERS
    Thomas Finger; Fiscal Year: 1992
    ..The third pilot project involves application of new technology (in vivo electrochemistry) to measure diffusion of odorants in the olfactory mucus...
  41. Electrostatic Formation and Transport of Small Droplets
    Thomas Jones; Fiscal Year: 2002
    ..Thus the perceived obstacles of high-field electrochemistry and heating can be avoided...
  42. A Novel Device for Determination of GFR Markers
    Bikas Vaidya; Fiscal Year: 2005
    ..This device is based on an innovative method that combines electrochemistry, solid phase extraction (SPE) and colorimetry...
  43. AGE INDUCED CHANGES IN MONOAMINE PRESYNAPTIC FUNCTION
    Greg Gerhardt; Fiscal Year: 2002
    ..He will employ in vivo electrochemistry recordings to evaluate the DAT, and microdialysis to assess changes in extracellular dopamine and dopamine ..
  44. Rapid Molecular Detection of PML/RARalpha
    Vincent Gau; Fiscal Year: 2002
    ..PROPOSED COMMERCIAL APPLICATIONS: GeneFluidics' Life Science/Electrochemistry Laboratory is located in Torrance, CA, a business/industrial area of Los Angeles, CA...
  45. NMDA RECEPTOR AND BEHAVIORAL TOXICITY OF LEAD
    Deborah Cory Slechta; Fiscal Year: 2002
    ..using behavioral baselines in conjunction with systemic and intra-NAC pharmacological probes and in vivo electrochemistry. The proposed experiments will further determine the extent of Pb as a risk factor, further elucidate and ..
  46. SYNTHESIS AND ELECTROCHEMISTRY OF THIOPHENE IMIDES
    RONALD NOFTLE; Fiscal Year: 2000
    ..Research in this direction will be the subject of future proposals. ..
  47. Low Cost, Accurate, Portable Blood Lead Analyzer
    Jan Lewandowski; Fiscal Year: 2002
    ..The electrochemistry of the system is equivalent to the performance of a typical rotating electrode but no moving mechanical parts ..
  48. RECOVERY FROM METHAMPHETAMINE INDUCED NEURODEGENERATION
    Wayne Cass; Fiscal Year: 2001
    ..In vivo electrochemistry will be used to map potassium-evoked (calcium dependent) overflow of DA and DA clearance (uptake) in the ..
  49. SURFACE CONFINED COLLOIDAL AU--PROTEIN COMPLEXES
    MICHAEL NATAN; Fiscal Year: 1999
    ..To that end, the proposed work will demonstrate direct electrochemistry of enzyme:Au complexes...
  50. ANALYSIS OF TYROSINE METABOLITES IN BODY FLUIDS
    PETER KISSINGER; Fiscal Year: 1980
    ..recently developed an extremely sensitive technique for phenolic compounds which takes full advantage of both electrochemistry and high performance liquid chromatography to make measurements on the 0...
  51. ELECTROCHEMICAL STUDY OF CNS REWARD CIRCUITS FOR COCAINE
    PATRICIA BRODERICK; Fiscal Year: 1990
    ..in brain dopaminergic systems, known to mediate brain reward, by studying release processes with in vivo electrochemistry. This is the first study of the acute and chronic release mechanisms of cocaine in vivo...
  52. Engineered Self-Assembling Fvs for Piezoimmunosensors
    Xiangqun Zeng; Fiscal Year: 2002
    ..Four bioengineering methods will be used to create an Fv-SAM that possesses the necessary attributes. Electrochemistry, network impedance analysis, and Atomic Force Microscope (AFM) will be used in parallel to characterize the ..
  53. Bicarbonate as a New Cofactor of Water Oxidase
    G Dismukes; Fiscal Year: 2001
    ..A possible role for BC in the catalase activity of the WOC will also be examined. Electrochemistry of manganese complexes with BC and other weak anions, and their capabilities to donate electrons to the WOC ..
  54. NEUROTROPHINS & NEURAL TRANSPLANTS IN PARKINSONS DISEASE
    DAVID YUREK; Fiscal Year: 1999
    ..In vivo electrochemistry and intracerebral dialysis will be used to determine whether these neurotrophic factors can improve and ..
  55. SPECTROSCOPY AND FUNCTION OF REDOX METALLOPROTEINS
    WILLIAM WOODRUFF; Fiscal Year: 2009
    ..of microfluidics and IR microscopy to time-resolved IR, (b) IR spectroscopy applied to monolayer protein electrochemistry, and (c) nuclear resonance vibrational spectroscopy (NRVS) applied to heme-copper oxidases.
  56. MODELS FOR THE ACTIVE SITE IN CYTOCHROME C OXIDASE
    C Elliott; Fiscal Year: 1980
    ..These will include: EPR, electrochemistry, magnetic susceptibility, optical spectroscopy, Mossbauer spectroscopy, ligand binding studies and simple ..
  57. ELECTROANALYTICAL PROBES OF EXOCYTOSIS
    Andrew Ewing; Fiscal Year: 2001
    ..The methods under development use electrochemistry to probe ultrasmall environments in neuroscience...
  58. ETHANOL EFFECTS IN CNS TISSUE IN LAS AND HAS RATS
    Michael Palmer; Fiscal Year: 2002
    ..activity of single neurons, whole-cell patch clamp recordings GABAA/C1 channel function, and in vivo electrochemistry to monitor presynaptic release and uptake of norepinephrine and other monoamines...
  59. Sensitive Detection of Bacteria Contaminated Platelets
    SEASON WONG; Fiscal Year: 2005
    ..This method can be used near the time of platelet being released for transfusion. The method uses electrochemistry to confirm the presence of bacteria...
  60. SURFACE ENHANCED RAMAN STUDIES OF BIOMOLECULES
    George Chumanov; Fiscal Year: 2000
    ..spectroscopies, including surface-enhanced Raman, FT-IR, FT-Raman and electroreflectance, together with electrochemistry will be used to characterize the protein at the metal surface and to quantitate the influence of various ..
  61. Multiplexed DNA-Mediated Electochemical Sensors
    Xing Yang; Fiscal Year: 2002
    ..This proposal aims to take advantages of the high sensitivity of the DNA-mediated electrochemistry to the stacking in DNA helixes and develop miniaturized , integrated, portable DNA sensors on a chip platform ..
  62. Composite Biomaterials for Neurite Outgrowth
    Diane Hoffman Kim; Fiscal Year: 2007
    ..the Principal Investigator in neuronal development, regeneration, and biomaterials and the Co-Investigator in electrochemistry, microfabrication, and surface characterization, to fabricate a platform capable of delivering precise ..