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Genomes and GenesSpecies | high risk pregnancySummarySummary: Pregnancy in which the mother and/or FETUS are at greater than normal risk of MORBIDITY or MORTALITY. Causes include inadequate PRENATAL CARE, previous obstetrical history (ABORTION, SPONTANEOUS), pre-existing maternal disease, pregnancy-induced disease (GESTATIONAL HYPERTENSION), and MULTIPLE PREGNANCY, as well as advanced maternal age above 35. Top Publications
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Publications
The young 'elderly' primipara revisitedP A Kraus
Kirwan Hospitalfor Women, Thuringowa, Central Queensland, Australia
Aust N Z J Obstet Gynaecol 41:450-2. 2001..Incidence of operative delivery, several other obstetric outcomes and the condition of the infant at birth were compared in various age groups. Both studies showed that the 30 to 34 age group was at increased risk of operative delivery..
Impact of advanced maternal age on pregnancy outcomeMuhieddine A-F Seoud
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon
Am J Perinatol 19:1-8. 2002..We conclude that multiparous women at least 40 years old have a higher antepartum complication rate including intrauterine fetal death compared with younger women...
Advanced maternal age and pregnancy outcomeV N Amarin
Department of Obstetrics and Gynaecology, Prince Ali Military Hospital, Karak, Jordan
East Mediterr Health J 7:646-51. 2001..We conclude that older women, managed by modern obstetric methods and delivered in a modern health-care centre, can expect good pregnancy outcomes...
Progestational agents to prevent preterm birth: a meta-analysis of randomized controlled trialsLuis Sanchez-Ramos
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of Florida Health Science Center, 653 1 West 8th Street, Jacksonville, FL 32209, USA
Obstet Gynecol 105:273-9. 2005..To perform an updated systematic review with meta-analysis to further elucidate the efficacy of progestational agents for the prevention of preterm births in patients at elevated risk...
Single vs weekly courses of antenatal corticosteroids for women at risk of preterm delivery: A randomized controlled trialD A Guinn
Maternal Fetal Medicine, Denver Health Medical Center, 777 Bannock St, MC 0660, Denver, CO 80204, USA
JAMA 286:1581-7. 2001..The practice of administering weekly courses of antenatal corticosteroids to pregnant women at risk of preterm delivery is widespread, but no randomized trial has established the efficacy or safety of this practice...
Psychiatric and substance use disorders as risk factors for low birth weight and preterm deliveryRosemary H Kelly
Department of Psychiatry, University of Washington, Seattle, Washington 98195, USA
Obstet Gynecol 100:297-304. 2002..We examined the associations between psychiatric and substance use diagnoses and low birth weight (LBW), very low birth weight (VLBW), and preterm delivery among all women delivering in California hospitals during 1995...
Inherited thrombophilias in pregnant patients: detection and treatment paradigmCharles J Lockwood
Department of Obstetrics and Gynecology, New York University School of Medicine, New York, New York 10016, USA
Obstet Gynecol 99:333-41. 2002....
Occlusion of arterio-arterial anastomosis manifesting as acute twin-twin transfusion syndromeT Y T Tan
Institute of Reproductive and Developmental Biology, Imperial College, Hammersmith Campus, London, UK
Placenta 25:238-42. 2004..This case report shows that the unmasking of unbalanced AVA configurations by occlusion of a protective AAA can manifest as TTTS...
High risk of unexpected late fetal death in monochorionic twins despite intensive ultrasound surveillance: a cohort studyOlivia Barigye
Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Institute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom
PLoS Med 2:e172. 2005..This prospective risk of fetal death in otherwise uncomplicated monochorionic diamniotic pregnancies after 32 wk of gestation might be obviated by a policy of elective preterm delivery, which now warrants evaluation...
Randomised clinical trials of fish oil supplementation in high risk pregnancies. Fish Oil Trials In Pregnancy (FOTIP) TeamS F Olsen
Maternal Nutrition Group, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen
BJOG 107:382-95. 2000..To test the postulated preventive effects of dietary n-3 fatty acids on pre-term delivery, intrauterine growth retardation, and pregnancy induced hypertension...
Toward a strategic approach for reducing disparities in infant mortalityCarol J Rowland Hogue
Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA
Am J Public Health 92:552-6. 2002..Effective action in these areas would not only improve infant mortality overall; it would also reduce racial and ethnic disparities in infant health...
Associations between maternal methylenetetrahydrofolate reductase polymorphisms and adverse outcomes of pregnancy: the Hordaland Homocysteine StudyEha Nurk
LOCUS for Homosysteine and Related Vitamins, Department of Public Health and Primary Health Care, University of Bergen, Norway
Am J Med 117:26-31. 2004..We studied whether two polymorphisms in the MTHFR gene (677C-->T and 1298A-->C) are associated with pregnancy complications, adverse outcomes, and birth defects...
Maternal and perinatal outcomes during expectant management of 239 severe preeclamptic women between 24 and 33 weeks' gestationBassam Haddad
CHI Creteil, Creteil, France
Am J Obstet Gynecol 190:1590-5; discussion 1595-7. 2004..This study was undertaken to determine maternal and perinatal outcomes after expectant management of severe preeclampsia between 24 and 33 weeks' gestation...
Endoscopic retrograde cholangiopancreatography (ERCP) in pregnancy without the use of radiationD C Simmons
Obstetrics and Gynecology Residency Program, Methodist Hospitals of Dallas, Dallas, Texas, USA
Am J Obstet Gynecol 190:1467-9. 2004..Two mothers were lost to follow-up; the outcomes of their pregnancies are unknown. CONCLUSION: The use of ERCP in pregnancy is limited because of the undesirable effects of radiation exposure to the fetus...
Trauma during pregnancy: an analysis of maternal and fetal outcomes in a large populationDina El-Kady
Department of Obstetrics and Gynecology, Division of Trauma Surgery at University of California Davis, School of Medicine, Sacramento, 95817, USA
Am J Obstet Gynecol 190:1661-8. 2004..This study highlights the need to optimize education in trauma prevention during pregnancy...
Aggressive tocolysis does not prolong pregnancy or reduce neonatal morbidity after preterm premature rupture of the membranesC Andrew Combs
Obstetrix Medical Group, Good Samaritan Hospital, San Jose, CA 95124, USA
Am J Obstet Gynecol 190:1723-8; discussion 1728-31. 2004..This study was undertaken to evaluate whether aggressive tocolysis improves pregnancy outcome after preterm premature rupture of the membranes (PPROM)...
Maternal birth weight in relation to plasma lipid concentrations in early pregnancyJennifer C Dempsey
Department of Epidemiology, University of Washington School of Public Health and Community Medicine, University of Washington, Seattle, Washington, USA
Am J Obstet Gynecol 190:1359-68. 2004..The purpose of this study was to determine the extent to which, if at all, maternal weight at birth is related to dyslipidemia during early pregnancy, which is a risk factor for preeclampsia...
Pregnancy after bariatric surgery is not associated with adverse perinatal outcomeEyal Sheiner
Department of Obstetrics and Gynecology, Faculty of Health Sciences, and of Surgery, Soroka University Medical Center, Ben Gurion University of the Negev Beer Sheva, Israel
Am J Obstet Gynecol 190:1335-40. 2004..The purpose of this study was to investigate the pregnancy outcome of patients after bariatric surgery...
Effect of pregnancy and stage of pregnancy on asthma severity: a systematic reviewHelen L Kwon
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520-8034, USA
Am J Obstet Gynecol 190:1201-10. 2004..Large, well-conducted population-based studies that explore different aspects of asthma severity are needed to substantiate these preliminary results...
Pregnancy outcomes in foreign-born and US-born womenF Forna
Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA
Int J Gynaecol Obstet 83:257-65. 2003..To compare pregnancy outcomes between foreign-born women and women born in the United States (US-born)...
Albumin in vaginal fluid is a marker of infection in early pregnancyI Vogel
Department of Obstetrics and Gynecology, Aarhus University Hospital, Aarhus, Denmark
Int J Gynaecol Obstet 83:307-8. 2003
Venous thromboembolism in pregnancy and the puerperium in Sudanese womenA A-R D Haggaz
Department of Obstetrics and Gynecology, University of Geizera, Wad Medani, Sudan
Int J Gynaecol Obstet 83:309-10. 2003
Psychological health in early pregnancy: relationship with nausea and vomitingB L Swallow
Department of Psychology, University of Lincoln, UK
J Obstet Gynaecol 24:28-32. 2004..Nausea and vomiting in early pregnancy is associated with psychiatric morbidity. The causal relationship between the two conditions has not been established...
Elective cervical cerclage versus serial ultrasound surveillance of cervical length in a population at high risk for preterm deliveryKatie M Groom
Imperial College London Research Group, Department of Obstetrics and Gynaecology, Institute of Reproductive and Development Biology, Queen Charlotte s and Chelsea Hospital, Hammersmith Campus, Imperial College School of Medicine, London, UK
Eur J Obstet Gynecol Reprod Biol 112:158-61. 2004..To compare pregnancy outcome for women at risk of preterm delivery undergoing elective cervical cerclage in the first trimester or serial transvaginal assessment of cervical length with cerclage only if indicated (control cases)...
Steroid cell tumour not otherwise specified during pregnancy: a case report and diagnostic work-up for virilisation in a pregnant patientAnnelie J E Vulink
Department of Obstetrics and Gynaecology, Medisch Spectrum Twente, PO Box 50000, Enschede, KA 7500, The Netherlands
Eur J Obstet Gynecol Reprod Biol 112:221-7. 2004..This is the first case report that describes a steroid cell tumour not otherwise specified during pregnancy. Differential diagnosis, a diagnostic work-up and treatment are discussed...
Single versus weekly courses of antenatal corticosteroids in preterm premature rupture of membranesMen Jean Lee
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, New York University, 550 First Avenue, Room 9E2, New York, NY 10016, USA
Obstet Gynecol 103:274-81. 2004..This study was performed to evaluate the efficacy of weekly courses of antenatal corticosteroids compared with a single course in women with preterm premature rupture of membranes (PROM)...
[Maternal complications associated with type of delivery in a university hospital]Roseli Mieko Yamamoto Nomura
Clínica Obstétrica do Hospital das Clínicas, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
Rev Saude Publica 38:9-15. 2004..To analyze maternal complications associated to type of delivery, comparing cesarean (c-) section with vaginal delivery...
Unexplained antepartum fetal deaths: what are the determinants?Rachana Chibber
Department of Obstetrics and Gynecology, King Faisal University Teaching Hospital, PO BOX 40126, 31952 Al Khobar, Kingdom of Saudi Arabia
Arch Gynecol Obstet 271:286-91. 2005..The objective was to assess fetal, antenatal, and pregnancy determinants of unexplained antepartum fetal death...
Progesterone and preterm birthShlomit Riskin-Mashiah
Am J Obstet Gynecol 190:1802-3; author reply 1803-4. 2004
Improving the management of opioid-dependent pregnanciesJodi S Dashe
Am J Obstet Gynecol 190:1806; author reply 1806-7. 2004
Obstetric performance of women aged over forty yearsE O Orji
Department of Obstetrics, Gynaecology and Perinatology, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria
East Afr Med J 81:139-41. 2004..05. CONCLUSION: There is a poor pregnancy outcome at fourty years and above. Patients need to be counselled for care in a specialised centre...
Does the number of previous caesarean deliveries affect maternal outcome and complication rates?H A Alchalabi
Department of Obstetrics and Gynaecology, Jordan University of Science and Technology, Irbid, Jordan
East Mediterr Health J 13:544-50. 2007..Post-operative pyrexia was commoner in women with 3 or more previous caesarean sections compared to those undergoing their first one...
The lowest surviving birth weight reported in a systemic lupus erythematosus patient: a review of the literatureJ Spiegel
Division of Rheumatology, Cedars Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
Lupus 16:52-5. 2007..This report represents the lowest birth weight pregnancy survival in a lupus patient and the first case of a survival in the second trimester with preeclampsia and HELLP syndrome...
[Obstetrics and its outcomes--"maternal health" in Germany: supporting pregnant women]Beate Schücking
Universitat Osnabruck
Pflege Z 59:400-3. 2006
[Characteristics of threats to pregnancy and labour in women over 39 y.o. in material of the District Hospital no. 2 in Rzeszów]Jarosław Janeczko
Oddział Ginekologii i Połoznictwa, Szpital Wojewódzki Nr 2 w Rzeszowie
Ginekol Pol 77:26-32. 2006..Comparison of obstetric results in women giving birth in age over 39 and those of younger women...
Successful pregnancy in a woman with glycogen storage disease type IIIShazia Bhatti
Department of Obstetrics and Gynaecology, National Women's Hospital, Auckland, New Zealand
Aust N Z J Obstet Gynaecol 46:168-9. 2006
Type 2 diabetes in pregnancy: a wolf in sheep's clothingN Wah Cheung
Centre for Diabetes and Endocrinology Research, Westmead Hospital, University of Sydney, Sydney, New South Wales, Australia
Aust N Z J Obstet Gynaecol 45:479-83. 2005..There is a need to highlight the dangers of type 2 diabetes in pregnancy to both patients and medical practitioners. Peri-conception care needs to improve to achieve better pregnancy outcomes...
Transvaginal ultrasonography in the prediction of preterm birth after treatment for cervical intraepithelial neoplasiaJoan M G Crane
Department of Obstetrics and Gynecology, Health Care Corporation of St John s, Memorial University of Newfoundland, Newfoundland, Canada
Obstet Gynecol 107:37-44. 2006..To estimate whether cervical length measured by transvaginal ultrasonography in women having had loop electrosurgical excision procedure (LEEP), cold knife conization, or cryotherapy predicts spontaneous preterm birth...
Use of uterine Doppler in an Australian level II maternity hospitalMariette J C Nagtegaal
Women s and Children Division Lyell McEwin Hospital, University of Adelaide, Elizabeth Vale, South Australia, Australia
Aust N Z J Obstet Gynaecol 45:424-9. 2005..To evaluate the clinical usefulness of uterine Doppler...
Pregnancy outcome in patients with primary Sjögren's syndrome. a case-control studyHans Jacob Haga
Department of Rheumatology, Esbjerg Central Hospital, 6700 Esbjerg, Denmark
J Rheumatol 32:1734-6. 2005..To study the outcome of pregnancy in patients with primary Sjögren's syndrome (pSS)...
[Late maternity in researchers' and medical staff's opinions]Małgorzata Sawicka
Z Katedry Pielegniarstwa Pomorskiej Akademii Pedagogicznej w Słupsku
Wiad Lek 57:262-5. 2004..These women cooperated with midwives and doctors very well, and that fact was strongly emphasized by the medical staff. Women over 35 years old declared stronger need of support, aid and knowledge than other groups of patients...
Brief intervention for prenatal alcohol use: a randomized trialGrace Chang
Department of Psychiatry, Brigham and Women s Hospital, Boston, MA, USA
Obstet Gynecol 105:991-8. 2005..To test the effectiveness of a brief intervention in the reduction of prenatal alcohol consumption by women when a partner is included...
Effect of coitus on recurrent preterm birthNicole P Yost
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, USA
Obstet Gynecol 107:793-7. 2006..To estimate the impact of sexual behavior on the risk of recurrent spontaneous preterm birth at less than 37 weeks of gestation...
Anal function during pregnancy and postpartum after ileal pouch anal anastomosis for ulcerative colitisTaku Kitayama
Department of Surgery, Division of Gastrointestinal and Colorectal Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan
Surg Today 35:211-5. 2005..Therefore, there are no factors directly prohibiting pregnancy and vaginal delivery in women who undergo IPAA for UC...
Ultrasonic evidence of placental calcification at 36 weeks' gestation: maternal and fetal outcomesDaniel McKenna
The Royal Jubilee Maternity Hospital, Grosvenor Road, Belfast, Northern Ireland, UK
Acta Obstet Gynecol Scand 84:7-10. 2005..Scans were performed at 36 weeks' gestation. The study group comprised patients demonstrating a grade III placenta, and the control group comprised patients not demonstrating a grade III placenta...
[Pregnancy beyond age 40 in 382 women: a retrospective study in Reunion Island]H Roman
Service de Gynecologie et Obstetrique, Groupe Hospitalier Sud Reunion, 97448 Saint Pierre, Ile de La Réunion, France
J Gynecol Obstet Biol Reprod (Paris) 33:615-22. 2004..To examine obstetrical and neonatal outcomes among women age 40 years and older...
[Pregnancy and delivery in women over 40 years old]Zbigniew Studziński
Z Oddziału Połozniczo Ginekologicznego Specjalistycznego Wojewódzkiego Szpitala im Janusza Korczaka w Słupsku
Wiad Lek 57:140-4. 2004..Our purpose was to describe the maternal and fetal outcomes of pregnancies in women of 40 years or older who delivered in the Department of Gynecology and Obstetrics in Hospital of Słupsk (Poland)...
[Role of maternal risk factors in foetal growth impairment]Krystyna Cieślik
Katedra Anatomii Funkcjonalnej AWF w Poznaniu
Pediatr Endocrinol Diabetes Metab 13:147-50. 2007..Clinical classification of maternal risk factors revealed four factors of most potent impact on foetal development, ie. maternal age, number of pregnancy and artificial and natural miscarriage history...
A case series of gastrointestinal abnormalities in fetuses with echogenic bowel detected during the antenatal periodH H Tan
Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899
Ann Acad Med Singapore 32:649-52. 2003..23%, an increased incidence (4.76%) is observed in those fetuses found to have antenatal EB. It is possible that the presence of IUGR is associated with a worse prognosis. Further prospective studies are needed to verify this association...
[Assessment of pregnancy and labour outcome and the condition of the newborn in primiparous women aged 35 and older]Małgorzata Skaźnik-Wikieł
II Katedry i Kliniki Połoznictwa i Ginekologii AM w Warszawie
Ginekol Pol 74:607-11. 2003..To assess the effect of maternally advanced age on pregnancy and labour outcome...
Maternal and perinatal outcome in nulliparous women aged 35 and olderSaed M Ziadeh
Consultant Obstetrics and Gynaecology, King Khalid National Guard Hospital, Jeddah, Jordan
Gynecol Obstet Invest 54:6-10. 2002..To compare the maternal and perinatal outcome of nulliparous women 35 years and older at the time of delivery with nulliparous women 25-29 years old...
Perinatal outcome of pregnancies in women aged 40 and overT Miletic
Department of Scientific Research General Hospital Sibenik, Croatia
Coll Antropol 26:251-8. 2002..There is a high risk of pre-gestational and gestational complications, and perinatal loss is high. Therefore, those pregnancies are not desirable from the medical point of view...
[Effect of risk on the child of an older mother (case-control study)]Silvia Romero-Maldonado
Ginecol Obstet Mex 70:295-302. 2002..CONCLUSIONS: Advance maternal age increases maternal morbidity and the risk for preterm delivery, low birth weight, asymptomatic hypoglycemia, wet lung syndrome and risk for chromosomopathies...
Multifetal pregnancy in older women and perinatal outcomesJun Zhang
Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, Bethesda, Maryland 20892, USA
Fertil Steril 78:562-8. 2002..To examine multifetal pregnancy in older women and perinatal outcomes...
Obstetric and prenatal outcome in menopausal women: a 12-year clinical studyS Antinori
RAPRUI Day Hospital (International Associated Research Institute for Human Reproduction, Via Properzio 6, 00192 Rome, Italy
Reprod Biomed Online 6:257-61. 2003..The 63-year-old woman reached full term pregnancy in July 1994, with delivery by Caesarean section of a boy in good health. Proper screening for risks has enabled this treatment to be given to a preselected group of patients...
Impact of maternal age and maternal somatic characteristics on newborn sizeSylvia Kirchengast
Institute for Anthropology, University of Vienna, A 1090 Vienna, Austria
Am J Hum Biol 15:220-8. 2003..Within term births taking place under sufficient psychosocial support, maternal somatic features had an important impact on newborn size...
Factors influencing the obstetric and perinatal outcome after oocyte donationGalit Sheffer-Mimouni
Departments of Obstetrics and Gynecology, The Lis Maternity Hospital, 6 Weizman St, Tel Aviv 46427, Israel
Hum Reprod 17:2636-40. 2002..We evaluated interactions between perinatal outcome after oocyte donation and various maternal factors...
Health risks for early (< or =19) and late (> or =35) childbearingSinan Ozalp
Osmangazi University Faculty of Medicine, Department of Obstetrics and Gynecology, Eskisehir, Turkey
Arch Gynecol Obstet 268:172-4. 2003..Prepregnancy counselling is essential for these age groups in order for a woman to be able to make an informed decision regarding the timing of childbearing...
Identification of a small supernumerary marker chromosome, r(2)(p10q11.2), and the problem of determining prognosisN Villa
Genetic Laboratory, S. Gerardo Hospital, Monza, Italy
Prenat Diagn 21:801-5. 2001..2 genomic region. Further molecular cytogenetic investigations of SMCs classified by DNA content and pregnancy outcome data should improve genetic counselling and risk evaluation...
Pregnancy outcome in the elderly gravida in Addis AbabaW Marai
Department of Obstetrics and Gynaecology, Jimma University, Addis Ababa, Ethiopia
East Afr Med J 79:34-7. 2002..Larger studies are needed to establish the exact magnitude of these associations and to show any significant difference in antepartum obstetric problems and fetal and neonatal outcome measures...
Screening for chromosomal anomalies: first or second trimester, biochemical or ultrasound?T Stojilkovic-Mikic
Royal Free and University College Medical School, University College London, Department of Obstetrics and Gynaecology, UK
Ann Acad Med Singapore 32:583-8; quiz 588-9. 2003..A major goal of screening test is to achieve maximum accuracy and minimum harm at low cost. The integrated test currently meets best those criteria...
Teenagers obstetric performanceS E Akinola
Department of Obstetrics and Gynecology, Muhayl General Hosptial, Muhayl, Kingdom of Saudi Arabia
Saudi Med J 22:580-4. 2001..Attention must therefore be turned to the young teenagers pregnancy, labor and delivery. To avoid poor outcome in this age group, age at first pregnancy should be encouraged from 16 years and above...
Safety of hydroxychloroquine in pregnant patients with connective tissue diseases: a study of one hundred thirty-three cases compared with a control groupNathalie Costedoat-Chalumeau
Centre Hospitalier Universitaire Pitie Salpetriere, Paris, France
Arthritis Rheum 48:3207-11. 2003..We now report our experience with 133 pregnancies in women being treated with HCQ, resulting in 117 live births. Results in the HCQ group are compared with those in a control group...
Prenatal diagnosis of 45,X and 45,X mosaicism: the need for thorough cytogenetic and clinical evaluationsBing Huang
Genzyme Genetics, Orange, CA 92868, USA
Prenat Diagn 22:105-10. 2002..Therefore, accurate identification of a cell line containing Y chromosome is critical for genetic counseling and postnatal management...
Pregnancy outcome after cervical cone excision: a case-control studyKatrine Donvold Sjøborg
Department of Obstetrics and Gynecology, Oestfold Hospital Trust, Fredrikstad, Norway
Acta Obstet Gynecol Scand 86:423-8. 2007..Outcome measures were perinatal mortality, length of gestation, birth weight and preterm premature rupture of membranes (pPROM)...
[Marfan syndrome in pregnancy: presentation of four cases and discussion]I Tzialidou
Medizinische Hochschule Hannover, Zentrum Frauenheilkunde, Abteilung I Frauenheilkunde und Geburtshilfe
Z Geburtshilfe Neonatol 211:36-41. 2007..If the aortic root diameter is < 40 mm, without progression in pregnancy, and in the absence of severe valve insufficiency, then pregnancy is in most cases well tolerated and vaginal delivery can be performed...
Molecular genetic testing for prenatal diagnosisUmadevi Tantravahi
Department of Pathology and Laboratory Medicine, Women and Infants Hospital, Brown University, 101 Dudley Street, Providence, RI 02905, USA
Clin Lab Med 23:481-502. 2003..The next few decades hold the promise of many more advances in genetic testing, drug discovery, and therapy...
The use of LMWH in pregnancies at risk: new evidence or perception?I D Walker
Department of Haematology, Glasgow Royal Infirmary, Glasgow, UK
J Thromb Haemost 3:778-93. 2005
[Fetal abnormalities and prognosis associated with increased nuchal translucency and abnormal karyotype]Fátima Aparecida Targino Saldanha
Clinica Obstetrica, Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo, Brazil
Rev Assoc Med Bras 55:54-9. 2009..Incidence of structural abnormalities and pregnancy outcome was also described in fetuses with increased NT and abnormal karyotype...
From Braxton Hicks to preterm labour: the constitution of risk in pregnancyKaren MacKinnon
Rural Maternity Research, Vancouver, British Columbia, Canada
Can J Nurs Res 38:56-72. 2006..The study also exposes ways in which biomedical constructions of risk and preterm labour affect the organization of health services, including nursing practice...
Implementation and case-study results of potentially better practices for collaboration between obstetrics and neonatology to achieve improved perinatal outcomesMara Zabari
Department of Perinatology and Neonatal Intensive Care Unit, Providence St Vincent Medical Center, Portland, Oregon, USA
Pediatrics 118:S153-8. 2006..Five NICUs from the Vermont Oxford Network's Evidence-Based Quality Improvement Collaborative in Neonatal and Perinatal Medicine tested potentially better practices that overlap obstetric and NICU care...
Significance of ultrasound vaginal cervicometry in predicting preterm deliveryMichal Mara
Department of Obstetrics and Gynecology, 1st Faculty of Medicine, Charles University and the General Faculty Hospital, Prague, Czech Republic
Med Sci Monit 8:MT72-7. 2002..The objective of the study was to verify whether ultrasound vaginal cervicometry, performed in the 18th-20th week of gestation, can effectively predict preterm delivery...
Hysteroscopic metroplasty improves gestational outcome in women with recurrent spontaneous abortionEdoardo Valli
Department of Obstetrics and Gynecology, Tor Vergata University, Rome, Italy
J Am Assoc Gynecol Laparosc 11:240-4. 2004..5%). CONCLUSION: Our data suggest that hysteroscopic septum incision can improve pregnancy outcome in patients with RSA associated with septate uterus...
Genetic amniocentesis in multiple pregnancyErno Toth-Pal
1st Department of Obstetrics and Gynecology, Faculty of Medicine, Semmelweis University, Budapest, Hungary
Fetal Diagn Ther 19:138-44. 2004..Here we analyze our experience with genetic amniocentesis in multiple pregnancies over the past 10 years...
Antenatal fetal assessment: contraction stress test, nonstress test, vibroacoustic stimulation, amniotic fluid volume, biophysical profile, and modified biophysical profile--an overviewLawrence D Devoe
Section of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Medical College of Georgia, Augusta, GA 30912, USA
Semin Perinatol 32:247-52. 2008....
Prenatal screening for Down syndrome: current and future methodsJacob A Canick
Division of Prenatal and Special Testing, Department of Pathology and Laboratory Medicine, Women and Infants Hospital, Brown Medical School, Providence, RI 02905, USA
Clin Lab Med 23:395-411. 2003..In the next few years, that goal will probably be achieved...
Unnecessary cesarean delivery in Louisiana: an analysis of birth certificate dataAzad A Kabir
Tulane Center for Clinical Effectiveness and Prevention, Tulane University School of Public Health, New Orleans, LA 70112, USA
Am J Obstet Gynecol 190:10-9; discussion 3A. 2004..CONCLUSION: The proportions of potentially unnecessary cesarean deliveries are relatively high in Louisiana. It is important to explore the influence of nonclinical factors on unnecessary cesarean delivery to reduce the cesarean rates...
Methamphetamine use during pregnancy: maternal and neonatal implicationsMeadow M Good
Division of Maternal Fetal Medicine, Department of Obstetrics Gynecology, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
Obstet Gynecol 116:330-4. 2010..To report the demographic characteristics and clinical morbidity of methamphetamine-exposed pregnancies compared with control patients in a tertiary care, urban, academic medical center...
Changes in nuchal translucency thickness in normal and abnormal karyotype fetusesMaria A Zoppi
Department of Obstetrics and Gynecology, Prenatal and Preimplantation Genetic Diagnosis, Fetal Therapy, Ospedale Microcitemico, Cagliari, Italy
BJOG 110:584-8. 2003..7-4.0). CONCLUSION: In fetuses with abnormal karyotype, the second nuchal translucency measurement tends to be increased or unchanged, while in normal cases the size of nuchal translucency is generally reduced...
Perinatal significance of diagnosing glucose intolerance during pregnancy with portable glucose meterPeter Jakobi
Department of Obstetrics and Gynecology, Rambam Medical Center, Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel
J Perinat Med 31:140-5. 2003..Such an approach is time and resource saving and more convenient for both patients and health providers...
Genetic sonography: an option for women of advanced maternal age with negative triple-marker maternal serum screening resultsGreggory R DeVore
Perinatology Research Branch, National Institute of Child Health and Human Development National Institutes of Health, Bethesda, Maryland, USA
J Ultrasound Med 22:1191-9. 2003..To determine whether offering genetic sonography to patients 35 years of age and older with negative maternal serum triple-marker screening results will result in an increase in the detection rate of trisomy 21...
Living with changing expectations for women with high-risk pregnancies: a Parse method studyCynthia A MacDonald
Halton Healthcare Services
Nurs Sci Q 22:74-82. 2009..Findings enhance the theory of humanbecoming as well as enhance understanding of the experience of living with changing expectations. Recommendations for future research and practice are discussed...
Does midtrimester cervical length ≥25 mm predict preterm birth in high-risk women?John Owen
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Alabama, Birmingham, AL, USA
Am J Obstet Gynecol 203:393.e1-5. 2010..We sought to assess pregnancy outcome along a continuum of cervical lengths (CLs) ≥25 mm...
[Monoamnotic twin pregnancy. Multicenter study]Witold Malinowski
Ginekol Pol 77:17-25. 2006..These pregnancies can be diagnosed reliably by ultrasound in most cases. Electively admitted women for inpatient fetal monitoring could be improved neonatal survival and decreased perinatal morbidity...
Specialized care for twin gestations: improving newborn outcomes and reducing costsR J Ruiz
University of Texas Health Science Center, San Antonio, USA
J Obstet Gynecol Neonatal Nurs 30:52-60. 2001....
Obstetrics and perinatal outcomes of Thai pregnant adolescents: a retrospective studySathja Thato
Faculty of Nursing, Chulalongkorn University, Vidhayakitt bldg floor 12, Phyathai Rd, Pathumwan, Bangkok 10330, Thailand
Int J Nurs Stud 44:1158-64. 2007Adolescent pregnancy is considered a high risk pregnancy.
In-home nursing care for women with high-risk pregnancies: outcomes and costM J Harrison
Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada
Obstet Gynecol 97:982-7. 2001....
Persistent intrahepatic right umbilical vein in the fetus: a benign anatomic variantS Blazer
Department of Neonatology, Rambam Medical Center, Faculty of Medicine, Technion Israel
Obstet Gynecol 95:433-6. 2000..To evaluate outcomes of fetuses with antepartum sonographic diagnoses of persistent intrahepatic right umbilical veins...
[Pregnancy outcome in women with rheumatic heart disease]Jian Hua Lin
Department of Obstetrics and Gynecology, Affiliated Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
Zhonghua Fu Chan Ke Za Zhi 42:315-9. 2007..To evaluate the pregnancy outcome of women with rheumatic heart disease...
Factors affecting outcome in post-term birthM K Campbell
Department of Epidemiology, University of Western Ontario, London, Canada
Curr Opin Obstet Gynecol 9:356-60. 1997..While there is no longer increased mortality associated with post-term birth per se, this is very much the result of clinical selection factors and modern perinatal management. Post-term pregnancies remain an obstetrical risk group...
Juggling type 1 diabetes and pregnancy in rural AustraliaRosemary King
School of Nursing, University of Ballarat, PO Box 663, Ballarat, 3353, Victoria, Australia
Midwifery 25:126-33. 2009..Additionally, we aimed to describe the women's engagement with, and expectations of, health-care providers during this period, and subsequently highlight potential service and informational gaps...
Stress, symptoms, self-monitoring confidence, well-being, and social support in the progression of preeclampsia/gestational hypertensionKathleen D Black
Department of Nursing at the Temple University College of Health Professions, Philadelphia, PA 19140, USA
J Obstet Gynecol Neonatal Nurs 36:419-29. 2007..Women with mild and severe preeclampsia/gestational hypertension were compared for differences in these variables...
Laser-assisted hatching in assisted reproductionM Montag
Department of Endocrinology and Reproductive Medicine, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
Croat Med J 40:398-403. 1999..The use of a 1.48 um diode laser for assisted hatching was investigated in animal experimentation. Laser assisted hatching was offered to patients with advanced maternal age to evaluate a possible benefit...
Second trimester placental location as a predictor of an adverse pregnancy outcomeE F Magann
Department of Obstetrics and Gynecology, University of Western Australia, Perth, Australia
J Perinatol 27:9-14. 2007..To determine if the second trimester placental location is associated with perinatal outcomes...
Pregnancy after thoracic organ transplantationDanny W Wu
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Columbia University Medical Center, New York, NY 10032, USA
Semin Perinatol 31:354-62. 2007..For most cases, given the need for close collaboration and frequent monitoring, these patients are best managed at their primary transplant institution in collaboration with local or referring physicians...
Ultrasound detection of placental insufficiency in women with elevated second trimester serum alpha-fetoprotein or human chorionic gonadotropinMeghana Toal
Department of Obstetrics and Gynaecology Maternal Fetal Medicine Division Placenta Clinic, Mount Sinai Hospital, University of Toronto, Toronto ON
J Obstet Gynaecol Can 30:198-206. 2008....
Evaluation and development of potentially better practices for perinatal and neonatal communication and collaborationJudy Ohlinger
Akron Children s Hospital, Neonatal Intensive Care Unit, One Perkins Sq, Akron, OH 44308, USA
Pediatrics 118:S147-52. 2006..Antepartum and intrapartum maternal attributes and interventions also were considered important measurements to identify practice variations and their relationship to neonatal outcomes for ongoing obstetric and neonatal collaboration...
Prevalence of viral DNA in amniotic fluid of low-risk pregnancies in the second trimesterA A Baschat
Center for Advanced Fetal Care, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland, Baltimore, Maryland 21201-1703, USA
J Matern Fetal Neonatal Med 13:381-4. 2003..The mechanism, significance and effects of this asymptomatic viral presence require further study...
Severe preeclampsia is associated with high inhibin A levels and normal leptin levels at 7 to 13 weeks into pregnancyLaurent J Salomon
, , 157 rue de la Porte-de-Trivaux, 92140 Clamart, France
Am J Obstet Gynecol 189:1517-22. 2003..93; 95% CI, 1.83, 13.28). CONCLUSION: High serum inhibin A levels in the first trimester of pregnancy could be used as an early risk marker for preeclampsia...
Comparison of age at first full-term pregnancy between women with breast cancer and women with benign breast diseasesAreti Lagiou
Department of Hygiene and Epidemiology, School of Medicine, University of Athens, Athens, Greece
Int J Cancer 107:817-21. 2003..The finding is accentuated by the fact that women with benign breast diseases are already at a relatively high risk for breast cancer...
[Elective cesarean section--delivery mode of the future or social misconception?]P Husslein
Universitätsklinik für Frauenheilkunde Wien, Abteilung für Geburtshilfe und Gynäkologie, Wahringer Gurtel 18 20, A 1090 Wien
Ther Umsch 59:660-6. 2002..It cannot be stressed enough that, in this context, comprehensive information and rigorous documentation are indispensable requirements...
Research Grants
- FETAL MAGNETOENCEPHALOGRAPHY AND EVOKED POTENTIALSCurtis Lowery; Fiscal Year: 2006..Determine the maturation of brain responses in-utero and compare the responses to newborns in a normal population to generate normative data6. Determine fetal brain development in abnormal fetuses ..
- FETAL MAGNETOENCEPHALOGRAPHY AND EVOKED POTENTIALSCurtis L Lowery; Fiscal Year: 2010..Relevance: In this proposal our goal is to further the development of techniques to improve validation procedure for auditory and visual evoked responses and fetal spontaneous brain activity. ..
- FETAL MAGNETOENCEPHALOGRAPHY AND EVOKED POTENTIALSCurtis Lowery; Fiscal Year: 2009..Relevance: In this proposal our goal is to further the development of techniques to improve validation procedure for auditory and visual evoked responses and fetal spontaneous brain activity. ..
- Temporal-Spatial Biomagnetic Fields of the FetusCurtis Lowery; Fiscal Year: 2004..In the future, the device, analysis tools, and datasets should be accessible to outside researchers for their own studies and collaborating efforts, by means of secure and fast Internet access. ..
- FETAL MAGNETOENCEPHALOGRAPHY AND EVOKED POTENTIALSCurtis Lowery; Fiscal Year: 2000..We now propose the design and construction of a large, curved array (850 cm2) engineered to fit the contour of the mother's anterior abdominal wall and to allow non-invasive fetal neurological evaluation. ..
- Vaginal Ultrasound Cerclage TrialJohn Owen; Fiscal Year: 2007..correlate these markers with the success of failure of cerclage B. further define possible mechanisms of early spontaneous preterm birth. ..
- Midcareer Award in Patient-Oriented ResearchJohn Owen; Fiscal Year: 2007..abstract_text> ..
- BAYLOR BIRCWH PROGRAMJoe Simpson; Fiscal Year: 2004..These goals are vital to public health in contributing to the establishment of methods for production of safe, effective, quality herbal extracts for consumer use. ..
- Evaluation of a Natural Experiment to Improve Statewide Depression Care in MNLeif Solberg; Fiscal Year: 2007..Finally, by conducting the study in cooperation with those who pay for and deliver the care, the project will demonstrate a new approach to research-practice partnerships. ..
- Identifying Newborns with Fragile X: Planning GrantDonald Bailey; Fiscal Year: 2005..abstract_text> ..
- Training in Epidemiology and Clinical Trials (TECT)David Grimes; Fiscal Year: 2007....
- Using GIS to Study IDU Risk Environments in TijuanaKIMBERLY BROUWER; Fiscal Year: 2007..Data generated from this study will be used by the applicant to develop a subsequent R01 application. ..
- Screening & Brief Intervention of Problem Drinking WomenGrace Chang; Fiscal Year: 2007..This proposed targeted study of women responds to PA-02-168, which seeks research on screening and interventions in medical settings, and builds upon our previous research on brief interventions for pregnant women. ..
- Mechanisms of myometrial healing and regenerationCatalin Buhimschi; Fiscal Year: 2006....
- Improving Employment among Gynecologic Cancer SurvivorsLINDA FRAZIER; Fiscal Year: 2006....
- The Role of Inflammation and Parity on GDM and Type 2 DMWanda Nicholson; Fiscal Year: 2007..This award will give Dr. Nicholson the dedicated time and experience she needs to develop into an independent clinical investigator ..
- The NonCancer Care of Elderly Colorectal Cancer PatientsLaura Mae Baldwin; Fiscal Year: 2006..abstract_text> ..
- Determinats of Body Composition in Rheumatoid ArthritisJon Giles; Fiscal Year: 2007..3. Identify the inflammatory and non-inflammatory factors associated with altered body composition phenotypes, adipokine profiles, and insulin resistance in patients with RA . ..
- Gene Environment Interaction in Head and Neck CancerAndrew Olshan; Fiscal Year: 2005..The proposed study should contribute knowledge on gene-environment interactions for cancer of the head and neck, but also for other tobacco- and alcohol-related cancers and possibly cancers of unknown etiology. ..
- PREDICTING FETAL ACIDEMIA WITH INTRAPARTUM ELECTRONIC FETAL HEART RATE MONITORINGGeorge A Macones; Fiscal Year: 2010..But it has never been shown to improve the health of women or their babies. This study will begin to fill the knowledge gap that exists between what obstetricians see every day on EFM and how babies are actually doing. ..
- Epidemiology of Ovarian AgeJennie Kline; Fiscal Year: 2003..2. To conduct exploratory studies, using data from the Oocyte study, to assess whether or not skewed X-inactivation is associated with advanced ovarian age. ..
- FETAL SWALLOWING--CENTRAL DIPSOGENIC MECHANISMSMichael Ross; Fiscal Year: 2002....
- EPIDEMIOLOGY OF TRISOMY AND OVARIAN AGEJennie Kline; Fiscal Year: 2001....
- Developmental Phonological Dyslexia: Neural MechanismsRichard Frye; Fiscal Year: 2007..In addition, the insight provided by this research will help guide the development of improved methods of diagnosis, rehabilitation, treatment and long-term monitoring of individuals with developmental cognitive disorders. ..
- Evolving HIV/STI risk environments of FSWs on the Mexico/U.S. BorderKimberly C Brouwer; Fiscal Year: 2010....
- Liposomal Opioids Extend Analgesia in Laboratory AnimalsLisa Krugner Higby; Fiscal Year: 2007..If proven efficacious, these analgesic regimens would lead to a significant change in the post-surgical care of animals used in biomedical research and veterinary medicine. ..
- Race Related Stressors and Preterm Birth in African American WomenCarmen Giurgescu; Fiscal Year: 2009..By understanding how neighborhood conditions and experiences of discrimination contribute to preterm birth, we can target programs and interventions that reduce the risk for preterm birth in African-American women. ..
- A Prospective Cohort Study of Migraines, Platelet Activation, and PreeclampsiaMichelle Williams; Fiscal Year: 2009....
- Mechanisms of Programmed Gestational HyperphagiaMICHAEL GLENN ROSS; Fiscal Year: 2010..These studies will provide important new information elucidating mechanisms for programming of orexigenic-mediated ingestive behavior, and provide a model to determine strategies for the prevention of child and adult obesity. ..
- MRI of Fetal Ventriculomegaly: Morphology and OutcomeDeborah Levine; Fiscal Year: 2007..The results of this project have the potential to benefit the practice of radiologists, obstetricians, pediatricians, neonatologists, and pediatric neurologists involved in the care of pregnant women with fetuses with VM. ..
- MATERNAL DEHYDRATION--FETAL/AMNIOTIC FLUID HOMEOSTASISMichael Ross; Fiscal Year: 2000..The goal of this project is to identify safe and effective treatments which can reliably alter AF volume in cases of poly- or oligohydramnios. ..
- Brown Medical School/WIHRI Dept of Ob/Gyn WRHR ProgramDONALD COUSTAN; Fiscal Year: 2007..This multidisciplinary program will provide a new cadre of academic investigators who will further the scientific database and improve the health status of women. ..
- Liposomal Opioids Extend Analgesia in Laboratory AnimalsLisa Krugner Higby; Fiscal Year: 2006..If proven efficacious, these analgesic regimens would lead to a significant change in the post-surgical care of animals used in biomedical research and veterinary medicine. ..
- MATERNAL DEHYDRATION--FETAL & AMNIOTIC FLUID HOMEOSTASISMichael Ross; Fiscal Year: 1992..Studies of dehydration and rehydration of the ovine model represent a promising approach to understanding maternal-fetal water dynamics, while addressing a potentially critical problem in perinatal medicine...
- FETAL SWALLOWING--ONTOGENY AND REGULATIONMichael Ross; Fiscal Year: 1993..The ovine model offers the opportunity to study, in a precocial species, the ontogeny of "thirst" physiology, an important but relatively unexplored area of perinatal physiology...
- AN ENHANCED BRIEF INTERVENTION FOR PRENATAL ALCOHOL USEGrace Chang; Fiscal Year: 2002..abstract_text> ..
- Patients, Clinics, and Systems: Screening for Alcohol UseGrace Chang; Fiscal Year: 2007..The proposed study site is the Young Adult Reproductive Health Service, run by the Brigham and Women's Hospital in conjunction with Children's Hospital for the past two decades, and serves 200 new patients annually. ..
- ENHANCED EVALUATION OF FETAL CNS WITH ULTRAFAST MRIDeborah Levine; Fiscal Year: 2002..Thus the results of this study could significantly decrease morbidity of fetuses with ventriculomegaly. ..
- Overweight in Children: A New View Using the Population Attributable FractionDeborah Rosenberg; Fiscal Year: 2007....
