- Soft sweeps: molecular population genetics of adaptation from standing genetic variation
Section of Evolutionary Biology, Department of Biology II, Ludwig Maximilians University Munich, Germany
Genetics 169:2335-52. 2005
..We find that soft sweeps with weaker selective footprints are likely under both scenarios if the mutation rate and/or the selection coefficient is high...
- Molecular responses to dehydration and low temperature: differences and cross-talk between two stress signaling pathways
Laboratory of Plant Molecular Biology, Tsukuba Life Science Center, Institute of Physical and Chemical Research RIKEN, Tsukuba, 305 0074, Japan
Curr Opin Plant Biol 3:217-23. 2000
..Recent studies are providing evidence of differences between dehydration-signaling and cold-stress-signaling cascades, and of cross-talk between them...
- Evolution of high mutation rates in experimental populations of E. coli
P D Sniegowski
Department of Biology, University of Pennsylvania, Philadelphia 19104, USA
Nature 387:703-5. 1997
..Our results corroborate computer simulations of mutator evolution in adapting clonal populations, and may help to explain observations that associate high mutation rates with emerging pathogens and with certain cancers...
- Adaptive radiation in a heterogeneous environment
P B Rainey
Department of Plant Sciences, University of Oxford, UK
Nature 394:69-72. 1998
..These results demonstrate that the elementary processes of mutation and selection alone are sufficient to promote rapid proliferation of new designs and support the theory that trade-offs in competitive ability drive adaptive radiation...
- The population genetics of ecological specialization in evolving Escherichia coli populations
V S Cooper
Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
Nature 407:736-9. 2000
..Thus, antagonistic pleiotropy appears more important than mutation accumulation for the decay of unused catabolic functions in these populations...
- OsDREB genes in rice, Oryza sativa L., encode transcription activators that function in drought-, high-salt- and cold-responsive gene expression
Joseph G Dubouzet
Biological Resources Division, Japan International Research Center for Agricultural Sciences JIRCAS, 1 1 Ohwashi, Tsukuba, Ibaraki 305 8686, Japan
Plant J 33:751-63. 2003
..OsDREB1A is potentially useful for producing transgenic monocots that are tolerant to drought, high-salt, and/or cold stresses...
- Sexually antagonistic male adaptation triggered by experimental arrest of female evolution
W R Rice
Department of Biology, University of California, Santa Cruz 95064, USA
Nature 381:232-4. 1996
..This male adaptation leads to a reduction in female survivorship, which is mediated by an increased rate of remating and increased toxicity of seminal fluid...
- Optimality and evolutionary tuning of the expression level of a protein
Department of Molecular Cell Biology and Department of Physics of Complex Systems, The Weizmann Institute of Science, Rehovot 76100, Israel
Nature 436:588-92. 2005
..Thus, protein expression from the lac operon seems to be a solution of a cost-benefit optimization problem, and can be rapidly tuned by evolution to function optimally in new environments...
- Selection on heritable phenotypic plasticity in a wild bird population
Daniel H Nussey
Netherlands Institute of Ecology NIOO KNAW, Post Office Box 40, 6666 ZG Heteren, Netherlands
Science 310:304-6. 2005
..This temporal trend is concurrent with climate change causing a mismatch between the breeding times of the birds and their caterpillar prey. Continued selection on plasticity can act to alleviate this mismatch...
- Experimental evolution of parasites
Universitat Basel, Zoologisches Institut, Rheinsprung 9, 4051 Basel, Switzerland
Science 282:1432-5. 1998
..Understanding why parasite virulence seldom escalates similarly in natural populations could help us to manage virulence and deal with emerging diseases...
- Interacting adaptive processes with different timescales underlie short-term motor learning
Maurice A Smith
Division of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, USA
PLoS Biol 4:e179. 2006
..Our results suggest that motor adaptation depends on at least two distinct neural systems that have different sensitivity to error and retain information at different rates...
- Efficiency and ambiguity in an adaptive neural code
A L Fairhall
NEC Research Institute, 4 Independence Way, New Jersey 08540, USA
Nature 412:787-92. 2001
..The speed with which information is optimized and ambiguities are resolved approaches the physical limit imposed by statistical sampling and noise...
- An implicit plan overrides an explicit strategy during visuomotor adaptation
Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
J Neurosci 26:3642-5. 2006
..This suggests that the motor system requires that planned and executed trajectories remain congruous in visual space, and enforces this correspondence even at the expense of an opposing explicit task goal...
- Sensory adaptation
Graduate Program in Neurobiology and Behavior, University of Washington, United States
Curr Opin Neurobiol 17:423-9. 2007
..Over longer timescales, adaptation is often power-law-like, implying the coexistence of multiple timescales in a single adaptive process. Models demonstrate that this can result from mechanisms within a single neuron...
- The combined effect of drought stress and heat shock on gene expression in tobacco
Department of Biology, Technion Israel Institute of Technology, Technion City, Haifa 32000, Israel
Plant Physiol 130:1143-51. 2002
..Therefore, improving stress tolerance of plants and crops may require a reevaluation, taking into account the effect of multiple stresses on plant metabolism and defense...
- Different trajectories of parallel evolution during viral adaptation
H A Wichman
Department of Biological Sciences, University of Idaho, Moscow, ID 83844, USA
Science 285:422-4. 1999
..However, the order of these changes differed between replicates, and parallel substitutions did not reflect the changes with the largest beneficial effects or indicate a common trajectory of adaptation...
- Role of mutator alleles in adaptive evolution
Laboratoire de Mutagenese, Institut J Monod, CNRS Université Paris, France
Nature 387:700-2. 1997
..The parameters of the model have been set to values typical for Escherichia coli cultures, which behave in a manner similar to the model in long-term adaptation experiments...
- Transcriptome changes for Arabidopsis in response to salt, osmotic, and cold stress
Joel A Kreps
Torrey Mesa Research Institute, Syngenta, 3115 Merryfield Row, San Diego, California 92121, USA
Plant Physiol 130:2129-41. 2002
..Although these results identify hundreds of potentially important transcriptome changes, the biochemical functions of many stress-regulated genes remain unknown...
- Physiological adaptation of the cardiovascular system to high altitude
Erasme University Hospital, Brussels, Belgium
Prog Cardiovasc Dis 52:456-66. 2010
..Altitude exposure carries no identified risk of myocardial ischemia in healthy subjects but has to be considered as a potential stress in patients with previous cardiovascular conditions...
- Visual adaptation: physiology, mechanisms, and functional benefits
Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA
J Neurophysiol 97:3155-64. 2007
..I conclude with a brief discussion of some important open questions in the field...
- Persistence of motor adaptation during constrained, multi-joint, arm movements
R A Scheidt
Department of Biomedical Engineering, Northwestern University, Evanston, IL 60622, USA
J Neurophysiol 84:853-62. 2000
- Constraint to adaptive evolution in response to global warming
J R Etterson
University of Minnesota, Department of Ecology, Evolution and Behavior, Minnesota Center for Community Genetics, 1987 Upper Buford Circle, St Paul, MN 55108, USA
Science 294:151-4. 2001
..Predicted rates of evolutionary response are much slower than the predicted rate of climate change...
- Shifts in coding properties and maintenance of information transmission during adaptation in barrel cortex
Instituto de Neurociencias de Alicante UMH CSIC, Campus de San Juan, Sant Joan d Alacant, Spain
PLoS Biol 5:e19. 2007
..Our results suggest that adaptation enhances tactile representations in primary somatosensory cortex, where they could directly influence perceptual decisions...
- Adaptive norm-based coding of facial identity
School of Psychology, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
Vision Res 46:2977-87. 2006
..Component identities were also harder to detect in morphs of opposite than non-opposite face pairs. We propose an adaptive norm-based coding model of face identity...
- Quantifying generalization from trial-by-trial behavior of adaptive systems that learn with basis functions: theory and experiments in human motor control
Laboratory for Computational Motor Control, Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, Maryland 21205 2195, USA
J Neurosci 23:9032-45. 2003
- Precise adaptation in bacterial chemotaxis through "assistance neighborhoods"
Robert G Endres
Department of Molecular Biology, Princeton University, NJ 08544 1014, USA
Proc Natl Acad Sci U S A 103:13040-4. 2006
..We predict two limits of precise adaptation at large attractant concentrations: Either receptors reach full methylation and turn off, or receptors become saturated and cease to respond to attractant but retain their adapted activity...
- Mechanisms causing rapid and parallel losses of ribose catabolism in evolving populations of Escherichia coli B
V S Cooper
Center for Microbial Ecology, Michigan State University, East Lansing, Michigan 48824, USA
J Bacteriol 183:2834-41. 2001
- Costs and benefits of high mutation rates: adaptive evolution of bacteria in the mouse gut
E9916, , , , 156 rue de Vaugirard, 75015 Paris, France
Science 291:2606-8. 2001
..The short-term advantages and long-term disadvantages of mutator bacteria could account for their frequency in nature...
- Adaptation to gradual as compared with sudden visuo-motor distortions
F A Kagerer
Motor Control Laboratory, Arizona State University, Tempe 85287 0404, USA
Exp Brain Res 115:557-61. 1997
..Results suggest that gradually increasing feedback distortion allows more complete adaptation than a large, sudden distortion onset...
- Pesticide resistance via transposition-mediated adaptive gene truncation in Drosophila
Yael T Aminetzach
Department of Biological Sciences, Stanford University, 371 Serra Mall, Stanford, CA 94305, USA
Science 309:764-7. 2005
..The insertion of this transposable element confers increased resistance to an organophosphate pesticide and has spread in D. melanogaster recently...
- Incipient speciation by divergent adaptation and antagonistic epistasis in yeast
Jeremy R Dettman
Department of Ecology and Evolutionary Biology, University of Toronto, Mississauga, Ontario, L5L 1C6, Canada
Nature 447:585-8. 2007
- Impacts of climate warming on terrestrial ectotherms across latitude
Curtis A Deutsch
Program on Climate Change and Department of Oceanography and Department of Biology, University of Washington, Seattle, WA 98195, USA
Proc Natl Acad Sci U S A 105:6668-72. 2008
..Our analyses imply that, in the absence of ameliorating factors such as migration and adaptation, the greatest extinction risks from global warming may be in the tropics, where biological diversity is also greatest...
- A 3'UTR pumilio-binding element directs translational activation in olfactory sensory neurons
Julia A Kaye
Cellular and Developmental Biology Program, 1 Shields Drive, University of California, Davis, Davis, CA 95616, USA
Neuron 61:57-70. 2009
- Dependence of bacterial chemotaxis on gradient shape and adaptation rate
Interdisziplinares Zentrum fur Wissenschaftliches Rechnen, University of Heidelberg, Heidelberg, Germany
PLoS Comput Biol 4:e1000242. 2008
..RapidCell is available from the authors upon request...
- Applications of prism adaptation: a tutorial in theory and method
Gordon M Redding
Department of Psychology, Illinois State University, Campus Box 4620, Normal, IL 61790 4620, USA
Neurosci Biobehav Rev 29:431-44. 2005
- A universal model for spike-frequency adaptation
Department of Physics, University of Ottawa, Ottawa, Ontario, K1N 6N5, Canada
Neural Comput 15:2523-64. 2003
..As an extension of the model, we introduce a framework for combining an arbitrary spike generator with a generalized adaptation current...
- Parallel adaptations to high temperatures in the Archaean eon
Laboratoire de Biometrie et Biologie Evolutive, CNRS, Universite de Lyon, Université Lyon I, 43 Boulevard du 11 Novembre, 69622 Villeurbanne, France
Nature 456:942-5. 2008
..This analysis unifies apparently contradictory results into a coherent depiction of the evolution of an ecological trait over the entire tree of life...
- Population genomics of marine fishes: identifying adaptive variation in space and time
Einar E Nielsen
Technical University of Denmark, National Institute of Aquatic Resources, Vejlsøvej 39, Silkeborg, Denmark
Mol Ecol 18:3128-50. 2009
- Components of sensorimotor adaptation in young and elderly subjects
Institute for Physiology and Anatomy, German Sport University, 50927, Koln, Germany
Exp Brain Res 160:259-63. 2005
..This conclusion is supported by two additional findings: compared with young subjects our seniors performed less well on a cognitive screening test and acquired no explicit knowledge about the nature of the imposed visual distortion...
- Reviewing molecular adaptations of Lyme borreliosis spirochetes in the context of reproductive fitness in natural transmission cycles
Jean I Tsao
Department of Fisheries and Wildlife, Michigan State University, East Lansing, MI 48864, USA
Vet Res 40:36. 2009
..This holistic system approach may help researchers develop additional testable hypotheses about transmission processes, interpret laboratory results, and guide development of future LB control measures and management...
- Arabidopsis UVR8 regulates ultraviolet-B signal transduction and tolerance and contains sequence similarity to human regulator of chromatin condensation 1
Daniel J Kliebenstein
The Boyce Thompson Institute for Plant Research and Section of Genetics and Development, Cornell University, Ithaca, New York 14853, USA
Plant Physiol 130:234-43. 2002
..These results suggest that UVR8 acts in a UV-B signal transduction pathway leading to induction of flavonoid biosynthesis...
- Cerebellar LTD facilitates but is not essential for long-term adaptation of the vestibulo-ocular reflex
A M Van Alphen
Department of Neuroscience, Erasmus University Rotterdam, Dr Molenwaterplein 50, 3000 DR Rotterdam, The Netherlands
Eur J Neurosci 16:486-90. 2002
..Thus, while LTD may be necessary for short-term VOR adaptation, it facilitates but is not required for long-term adaptation of the VOR...
- Rapid regulation of light harvesting and plant fitness in the field
Umea Plant Science Center, Department of Plant Physiology, Umea University, SE 901 87 Umea, Sweden
Science 297:91-3. 2002
- Significance of the V-type ATPase for the adaptation to stressful growth conditions and its regulation on the molecular and biochemical level
K J Dietz
Department of Physiology and Biochemistry of Plants, Faculty of Biology, University of Bielefeld, D 33501 Bielefeld, Germany
J Exp Bot 52:1969-80. 2001
..The mechanisms known to regulate the V-ATPase are summarized in this paper with an emphasis on their implications for growth and development under stress...
- Adaptive responses to oxidative damage in three mutants of Caenorhabditis elegans (age-1, mev-1 and daf-16) that affect life span
Department of Molecular Life Science, Tokai University School of Medicine, Boseidai, Isehara, Kanagawa 259 1193, Japan
Mech Ageing Dev 123:1579-87. 2002
..This suggests that SOD and catalase do not play a role in the adaptive response against oxidative stress under hyperoxia, at least under these experimental conditions...
- Long-term characterization of firing dynamics of spontaneous bursts in cultured neural networks
Jaap van Pelt
Graduate School Neurosciences Amsterdam, Netherlands Institute for Brain Research, Neurons and Networks Research Group, 1105 AZ Amsterdam, The Netherlands
IEEE Trans Biomed Eng 51:2051-62. 2004
- Hybridization and adaptive mate choice in flycatchers
Department of Animal Ecology, Evolutionary Biology Centre, Uppsala University, SE-752 36 Uppsala, Sweden
Nature 411:45-50. 2001
..Apparent hybridization may thus represent adaptive mate choice under some circumstances...
- HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA
Cell Metab 3:187-97. 2006
- Chemotaxis: how bacteria use memory
Interdisziplinäres Zentrum für Wissenschaftliches Rechnen der Universität Heidelberg IWR, Im Neuenheimer Feld 368, D 69120 Heidelberg, Germany
Biol Chem 390:1097-104. 2009
..Moreover, noise in the adaptation system, which results from variations of the adaptation rate both over time and among cells, might be beneficial for the overall chemotactic performance of the population...
- Rapid, local adaptation of zooplankton behavior to changes in predation pressure in the absence of neutral genetic changes
Laboratory of Aquatic Ecology, Katholieke Universiteit Leuven, Ch. De Beriotstraat 32, B-3000 Leuven, Belgium
Proc Natl Acad Sci U S A 98:6256-60. 2001
- Evolution: the evolvability enigma
J F Brookfield
Institute of Genetics, University of Nottingham, Queens Medical Centre, NG7 2UH, Nottingham, UK
Curr Biol 11:R106-8. 2001
..To what extent should processes of gene expression and control be interpreted in terms of their capacity to allow future evolution as well as present adaptation?..
- Visual cortex: Fatigue and adaptation
Swiss Federal Institute of Technology and University of Zurich, Switzerland
Curr Biol 10:R605-7. 2000
..Recent results demonstrate that this visual adaptation is explained partly by a cellular mechanism acting in individual cortical neurons...
- Erythropoietin regulates hypoxic ventilation in mice by interacting with brainstem and carotid bodies
Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich, Switzerland
J Physiol 568:559-71. 2005
..These novel findings are relevant to understanding better respiratory disorders including those occurring at high altitude...
- Anabolism. Low mechanical signals strengthen long bones
Musculo Skeletal Research Laboratory, Department of Biomedical Engineering, State University of New York, Stony Brook, New York 11794 2580, USA
Nature 412:603-4. 2001
..As the strain levels generated by this treatment are three orders of magnitude below those that damage bone tissue, this anabolic, non-invasive stimulus may have potential for treating skeletal conditions such as osteoporosis...
- Differential gene expression by Paracoccidioides brasiliensis in host interaction conditions: representational difference analysis identifies candidate genes associated with fungal pathogenesis
Alexandre Melo Bailão
Laboratorio de Biologia Molecular, Instituto de Ciencias Biologicas, Universidade Federal de Goias, 74001 970 Goiania, Goias, Brazil
Microbes Infect 8:2686-97. 2006
..This work can facilitate functional studies of novel regulated genes that may be important for the survival and growth strategies of P. brasiliensis in humans...
- The evolutionary consequences of ecological interactions mediated through phenotypic plasticity
James A Fordyce
Department of Ecology and Evolutionary Biology, University of Tennessee, Knoxville, TN 37996, USA
J Exp Biol 209:2377-83. 2006
- Importance of hemodynamic forces as signals for exercise-induced changes in endothelial cell phenotype
M Harold Laughlin
Department of Biomedical Sciences, College of Veterinary Medicine, 1600 E Rollins Rd, University of Missouri, Columbia, MO 65211, USA
J Appl Physiol (1985) 104:588-600. 2008
..We conclude that available evidence suggests that exercise signals formation of beneficial endothelial cell phenotype at least in part through changes in SS and wall stretch in the arteries...
- Concurrent adaptations of left and right arms to opposite visual distortions
Institute of Physiology and Anatomy, German Sport University, 50927 Koln, Germany
Exp Brain Res 162:513-9. 2005
..The reduced aftereffects observed under bimanual conditions can be attributed to the well-known phenomenon of bimanual coupling, which is unrelated to adaptation...
- Escherichia coli acid resistance: tales of an amateur acidophile
John W Foster
Department of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile, Alabama 36695, USA
Nat Rev Microbiol 2:898-907. 2004
..Surprisingly, certain microorganisms that grow at neutral pH have elegantly regulated systems that enable survival during excursions into acidic environments. The best-characterized acid-resistance system is found in E. coli...
- Adaptive evolution of non-coding DNA in Drosophila
Section of Ecology, Behavior and Evolution, Division of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA
Nature 437:1149-52. 2005
..These results imply that, although positive selection is clearly an important facet of protein evolution, adaptive changes to non-coding DNA might have been considerably more common in the evolution of D. melanogaster...
- Maternal effects provide phenotypic adaptation to local environmental conditions
Laura F Galloway
Department of Biology, University of Virginia, Charlottesville, VA 22904 4328, USA
New Phytol 166:93-9. 2005
..Evaluating maternal environmental effects in an ecological context demonstrates that they may provide phenotypic adaptation to local environmental conditions...
- Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level
Corey B Moore
Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital and Murdoch University, Level 2 North Block, Royal Perth Hospital, Wellington Street, WA 6000, Australia
Science 296:1439-43. 2002
..At a population level, the degree of HLA-associated selection in viral sequence was predictive of viral load. These results support a fundamental role for HLA-restricted immune responses in driving and shaping HIV-1 evolution in vivo...
- Time course of change in vasodilator function and capacity in response to exercise training in humans
Toni M Tinken
Research Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool, UK
J Physiol 586:5003-12. 2008
- Kin selection and parasite evolution: higher and lower virulence with hard and soft selection
Department of Biology, University of California San Diego 92093, USA
Q Rev Biol 75:261-75. 2000
..We recognize that hard selection for virulence is more difficult to document, but we take our results to suggest that a kin selection model with soft selection may have general applicability...
- The art of the probable: system control in the adaptive immune system
R N Germain
Lymphocyte Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 1892, USA
Science 293:240-5. 2001
- Arabidopsis AtMYC2 (bHLH) and AtMYB2 (MYB) function as transcriptional activators in abscisic acid signaling
Biological Resources Division, Japan International Research Center for Agricultural Sciences, 1 1 Ohwashi, Tsukuba, Ibaraki 305 8686, Japan
Plant Cell 15:63-78. 2003
..These results indicate that both AtMYC2 and AtMYB2 proteins function as transcriptional activators in ABA-inducible gene expression under drought stress in plants...
- Introduced species and their missing parasites
Mark E Torchin
Marine Science Institute and Department of Ecology, Evolution and Marine Biology, University of California, Santa Barbara, California 93106, USA
Nature 421:628-30. 2003
- Cerebellar contributions to adaptive control of saccades in humans
Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
J Neurosci 29:12930-9. 2009
- Audiovisual temporal adaptation of speech: temporal order versus simultaneity judgments
Crossmodal Research Laboratory, Department of Experimental Psychology, University of Oxford, 9 South Parks Road, Oxford, OX1 3UD, UK
Exp Brain Res 185:521-9. 2008
- Selective adaptation in networks of cortical neurons
Faculties of Medicine, Technion Israel Institute of Technology, Haifa 31096, Israel
J Neurosci 23:9349-56. 2003
..The observation that selective adaptation arises naturally in a network of cortical neurons developing ex vivo indicates that this is an inherent feature of spontaneously organizing cortical networks...
- Sensorimotor adaptation in speech production
J F Houde
Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Science 279:1213-6. 1998
- The evolution of a pleiotropic fitness tradeoff in Pseudomonas fluorescens
R Craig MacLean
Department of Biology, McGill University, 1205 Avenue Docteur Penfield, Montreal, QC, Canada H3A 1B1
Proc Natl Acad Sci U S A 101:8072-7. 2004
..These results provide a possible explanation of conflicting accounts for the cost of specialization...
- Reduced climbing and increased slipping adaptation in cochlear hair cells of mice with Myo7a mutations
C J Kros
School of Biological Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK
Nat Neurosci 5:41-7. 2002
..We conclude that myosin VIIA participates in anchoring and holding membrane-bound elements to the actin core of the stereocilium. Myosin VIIA is therefore required for the normal gating of transducer channels...
- Genes commonly regulated by water-deficit stress in Arabidopsis thaliana
Elizabeth A Bray
Department of Botany and Plant Sciences, University of California, Riverside, CA 92521, USA
J Exp Bot 55:2331-41. 2004
..A more detailed analysis of genes involved in cell wall metabolism, indicated that there was a global decrease in expression of genes that promote cell expansion...
- The Arabidopsis thaliana SOS2 gene encodes a protein kinase that is required for salt tolerance
Department of Plant Sciences, University of Arizona, Tucson, AZ 85721, USA
Proc Natl Acad Sci U S A 97:3730-4. 2000
..This mutation abolishes SOS2 autophosphorylation, indicating that SOS2 protein kinase activity is required for salt tolerance...
- Intrinsic mechanisms for adaptive gain rescaling in barrel cortex
Instituto de Neurociencias de Alicante, Universidad Miguel Hernández de Elche Consejo Superior de Investigaciones Científicas, Campus de San Juan, 03550 Sant Joan d Alacant, Spain
J Neurosci 28:696-710. 2008
..Our results suggest that widely expressed intrinsic mechanisms participate in barrel cortex adaptation but that their recruitment is highly stimulus specific...
- Hsp101 is necessary for heat tolerance but dispensable for development and germination in the absence of stress
S W Hong
Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, AZ 85721, USA
Plant J 27:25-35. 2001
..The hot1-2 mutant also expresses Hsp101 in seeds, but at a tenfold reduced level, resulting in reduced thermotolerance of germinating seeds and underscoring the importance of Hsp101 to seed stress tolerance...
- Evolution of thermal dependence of growth rate of Escherichia coli populations during 20,000 generations in a constant environment
V S Cooper
Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
Evolution 55:889-96. 2001
..Antagonistic pleiotropy therefore is more likely to be responsible for the evolution of thermal specialization observed in maximum growth rate...
- Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation
School of Oceanography, University of Washington, Seattle, Washington 98195, USA
Nature 424:1042-7. 2003
..Some of these genes have obvious roles in determining the relative fitness of the ecotypes in response to key environmental variables, and hence in regulating their distribution and abundance in the oceans...
- Salinity tolerance of Populus
College of Biological Sciences and Technology, Beijing Forestry University, Beijing, China
Plant Biol (Stuttg) 12:317-33. 2010
..In future attempts towards increased salt resistance, barriers between different poplar sections must be overcome and application of novel biotechnological tools, such as gene stacking, are recommended...
- Maintaining a healthy SPANC balance through regulatory and mutational adaptation
School of Molecular and Microbial Biosciences, The University of Sydney, NSW 2006, Australia
Mol Microbiol 57:1-8. 2005
- Heat shock protein genes and their functional significance in fish
Faculty of Agricultural Sciences and AquaNet, University of British Columbia, Vancouver, BC, Canada
Gene 295:173-83. 2002
- Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes
D Ross Laybutt
Section of Islet Transplantation and Cell Biology, Joslin Diabetes Center, Boston, Massachusetts 02215, USA
J Biol Chem 278:2997-3005. 2003
..Thus, both the severity and duration of hyperglycemia appear to contribute to the deterioration of the beta-cell phenotype found in diabetes...
- Temporal expression of seven clock genes in the suprachiasmatic nucleus and the pars tuberalis of the sheep: evidence for an internal coincidence timer
Medical Research Council, Human Reproductive Sciences Unit, University of Edinburgh, Chancellor s Building, 49 Little France Crescent, Edinburgh EH16 4SB, Scotland, UK
Proc Natl Acad Sci U S A 99:13890-5. 2002
- Improving water use in crop production
J I L Morison
Department of Biological Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK
Philos Trans R Soc Lond B Biol Sci 363:639-58. 2008
- Limited transfer of learning between unimanual and bimanual skills within the same limb
Centre for Neuroscience Studies, Department of Anatomy and Cell Biology, Queen s University, Kingston, Ontario K7L 3N6, Canada
Nat Neurosci 9:1364-6. 2006
..These results suggest partial, but not complete, overlap in the learning processes involved in the acquisition of unimanual and bimanual skills...
- Cellular and developmental adaptations to hypoxia: a Drosophila perspective
Nuria Magdalena Romero
Instituto Leloir, Patricias Argentinas, Buenos Aires, Argentina
Methods Enzymol 435:123-44. 2007
..Paradoxically, Sima is a negative regulator of growth. This suggests that Sima is engaged in a negative feedback loop that limits growth upon stimulation of InR/TOR pathways...
- Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin
Jay F Storz
School of Biological Sciences, University of Nebraska, Lincoln, NE 68588, USA
Proc Natl Acad Sci U S A 106:14450-5. 2009
..The experimental measures of O(2)-binding properties corroborated the tests of selection by demonstrating a functional difference between the products of alternative alleles...
- Enhanced accumulation of BiP in transgenic plants confers tolerance to water stress
F C Alvim
Departamento de Biologia Vegetal, , , Minas Gerais, Brazil
Plant Physiol 126:1042-54. 2001
..These results suggest that overexpression of BiP in plants may prevent endogenous oxidative stress...
- The genetics of adaptive shape shift in stickleback: pleiotropy and effect size
Arianne Y K Albert
Department of Zoology and Biodiversity Research Centre, University of British Columbia, Vancouver, BC, Canada
Evolution 62:76-85. 2008
..Our results are consistent with predictions of the geometric model of adaptation. Shape evolution in stickleback results from a few genes with large and possibly widespread effects and multiple genes of smaller effect...
- Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptors
The Mary D Allen Laboratory for Vision Research, Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles 90089 9112, USA
Proc Natl Acad Sci U S A 98:9948-53. 2001
..We conclude that GCAPs strongly regulate GC activity in mouse rods, decreasing the flash sensitivity in darkness and increasing the incremental flash sensitivity in bright steady light, thereby extending the rod's operating range...
- Transgenerational plasticity is adaptive in the wild
Laura F Galloway
Department of Biology, University of Virginia, Charlottesville, VA 22904 4328, USA
Science 318:1134-6. 2007
..4 times greater fitness than otherwise. Transgenerational plasticity has evolved in response to natural variation in light and provides a flexible mechanism by which sedentary organisms cope with heterogeneous environments...
- Remodeling of blood vessels: responses of diameter and wall thickness to hemodynamic and metabolic stimuli
Axel R Pries
Department of Physiology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
Hypertension 46:725-31. 2005
- Response of plant metabolism to too little oxygen
Max Planck Institute of Molecular Plant Physiology, Am Muhlenberg 1, 14476 Golm, Germany
Curr Opin Plant Biol 6:247-56. 2003
..Recently, advances have been made in elucidating possible oxygen-sensing systems and regulatory components that are involved in these responses...
- Bacterial biofilms: from the natural environment to infectious diseases
Department of Veterinary Molecular Microbiology, Departments of Microbiology and Civil Engineering, Center for Biofilm Engineering, Montana State University, Bozeman, Montana, USA
Nat Rev Microbiol 2:95-108. 2004
..The implications of these survival and propagative mechanisms in the context of both the natural environment and infectious diseases are discussed in this review...
- Duration-dependent FMRI adaptation and distributed viewer-centered face representation in human visual cortex
Department of Psychology, University of Minnesota, 75 East River Parkway, Minneapolis, MN 55455, USA
Cereb Cortex 17:1402-11. 2007
..Our findings suggest that long- and short-term fMRI adaptations may reflect selective properties of different neuronal mechanisms...
- Prototype-referenced shape encoding revealed by high-level aftereffects
D A Leopold
, , Germany
Nat Neurosci 4:89-94. 2001
..The results suggest that the encoding of faces and other complex patterns draws upon contrastive neural mechanisms that reference the central tendency of the stimulus category...
- Adaptation and the cost of complexity
H A Orr
Department of Biology, University of Rochester, New York 14627, USA
Evolution 54:13-20. 2000
..The present results also suggest that one can define an effective number of dimensions characterizing an adapting species...
- The small noncoding DsrA RNA is an acid resistance regulator in Escherichia coli
Richard A Lease
Wadsworth Center, New York State Department of Health, Center for Medical Sciences, Albany, New York, USA
J Bacteriol 186:6179-85. 2004
..Whether DsrA targets acid resistance genes directly by base pairing or indirectly via perturbation of RpoS and/or H-NS is not known, but in either event, our results suggest that DsrA RNA may enhance the virulence of pathogenic E. coli...
- Transcriptional and physiological adaptation to defective protein-O-mannosylation in Candida albicans
Pilar D Cantero
Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Dusseldorf, Germany
Mol Microbiol 64:1115-28. 2007
..While known signalling pathways modulate adaptation for a short-term, long-term adaptation requires calcineurin, adjustments of remaining Pmt activities and of glycolytic flow...
- Representation of perceived object shape by the human lateral occipital complex
Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Science 293:1506-9. 2001
..These data indicate that the LOC represents not simple image features, but rather higher level shape information...