- Preload maintenance and the left ventricular response to prolonged exercise in men
E A Dawson
The Copenhagen Muscle Research Center, Department of Anaesthesia, Rigshospitalet, Blegdamsvej 9, DK 2100, Copenhagen Ø, Denmark
Exp Physiol 92:383-90. 2007
..Three hours of semi-supine cycling resulted in no evidence of a depression in left ventricular systolic function, while left ventricular diastolic function declined postexercise...
- OsDREB genes in rice, Oryza sativa L., encode transcription activators that function in drought-, high-salt- and cold-responsive gene expression
Joseph G Dubouzet
Biological Resources Division, Japan International Research Center for Agricultural Sciences (JIRCAS, 1-1 Ohwashi, Tsukuba, Ibaraki 305-8686, Japan
Plant J 33:751-63. 2003
..OsDREB1A is potentially useful for producing transgenic monocots that are tolerant to drought, high-salt, and/or cold stresses...
- Interacting adaptive processes with different timescales underlie short-term motor learning
Maurice A Smith
Division of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, USA
PLoS Biol 4:e179. 2006
..Our results suggest that motor adaptation depends on at least two distinct neural systems that have different sensitivity to error and retain information at different rates...
- Escherichia coli acid resistance: tales of an amateur acidophile
John W Foster
Department of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile, Alabama 36695, USA
Nat Rev Microbiol 2:898-907. 2004
..Surprisingly, certain microorganisms that grow at neutral pH have elegantly regulated systems that enable survival during excursions into acidic environments. The best-characterized acid-resistance system is found in E. coli...
- Impacts of climate warming on terrestrial ectotherms across latitude
Curtis A Deutsch
Program on Climate Change and Department of Oceanography and Department of Biology, University of Washington, Seattle, WA 98195, USA
Proc Natl Acad Sci U S A 105:6668-72. 2008
..Our analyses imply that, in the absence of ameliorating factors such as migration and adaptation, the greatest extinction risks from global warming may be in the tropics, where biological diversity is also greatest...
- Quantifying generalization from trial-by-trial behavior of adaptive systems that learn with basis functions: theory and experiments in human motor control
Laboratory for Computational Motor Control, Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, Maryland 21205 2195, USA
J Neurosci 23:9032-45. 2003
- Introduced species and their missing parasites
Mark E Torchin
Marine Science Institute and Department of Ecology, Evolution and Marine Biology, University of California, Santa Barbara, California 93106, USA
Nature 421:628-30. 2003
- Arabidopsis AtMYC2 (bHLH) and AtMYB2 (MYB) function as transcriptional activators in abscisic acid signaling
Biological Resources Division, Japan International Research Center for Agricultural Sciences, 1 1 Ohwashi, Tsukuba, Ibaraki 305 8686, Japan
Plant Cell 15:63-78. 2003
..These results indicate that both AtMYC2 and AtMYB2 proteins function as transcriptional activators in ABA-inducible gene expression under drought stress in plants...
- Cerebellar contributions to adaptive control of saccades in humans
Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
J Neurosci 29:12930-9. 2009
- Adaptation and the cost of complexity
H A Orr
Department of Biology, University of Rochester, New York 14627, USA
Evolution 54:13-20. 2000
..The present results also suggest that one can define an effective number of dimensions characterizing an adapting species...
- Bacterial biofilms: from the natural environment to infectious diseases
Department of Veterinary Molecular Microbiology, Departments of Microbiology and Civil Engineering, Center for Biofilm Engineering, Montana State University, Bozeman, Montana, USA
Nat Rev Microbiol 2:95-108. 2004
..The implications of these survival and propagative mechanisms in the context of both the natural environment and infectious diseases are discussed in this review...
- Duration-dependent FMRI adaptation and distributed viewer-centered face representation in human visual cortex
Department of Psychology, University of Minnesota, 75 East River Parkway, Minneapolis, MN 55455, USA
Cereb Cortex 17:1402-11. 2007
..Our findings suggest that long- and short-term fMRI adaptations may reflect selective properties of different neuronal mechanisms...
- Prototype-referenced shape encoding revealed by high-level aftereffects
D A Leopold
, , Germany
Nat Neurosci 4:89-94. 2001
..The results suggest that the encoding of faces and other complex patterns draws upon contrastive neural mechanisms that reference the central tendency of the stimulus category...
- Fundamental evolutionary limits in ecological traits drive Drosophila species distributions
Centre for Environmental Stress and Adaptation Research, Department of Genetics, University of Melbourne, Parkville, Melbourne 3010, Australia
Science 325:1244-6. 2009
..We predict that such species are likely to be constrained in their evolutionary responses to future climate changes...
- Understanding the adaptive growth strategy of Lactobacillus plantarum by in silico optimisation
Top Institute Food and Nutrition WCFS, Wageningen, The Netherlands
PLoS Comput Biol 5:e1000410. 2009
..Hence, these results provide thorough understanding of adaptive evolution, allowing in silico predictions of the resulting flux states, provided that the selective growth conditions favor yield optimization as the winning strategy...
- Constraint to adaptive evolution in response to global warming
J R Etterson
University of Minnesota, Department of Ecology, Evolution and Behavior, Minnesota Center for Community Genetics, 1987 Upper Buford Circle, St Paul, MN 55108, USA
Science 294:151-4. 2001
..Predicted rates of evolutionary response are much slower than the predicted rate of climate change...
- The fate of microbial mutators
J Arjan G M de Visser
Laboratory of Genetics, Wageningen University, Dreijenlaan 2, 6703 HA Wageningen, The Netherlands
Microbiology 148:1247-52. 2002
- Regulatory and metabolic rewiring during laboratory evolution of ethanol tolerance in E. coli
Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA
Mol Syst Biol 6:378. 2010
..Remarkably, these laboratory-evolved strains, by and large, follow the same adaptive paths as inferred from our coarse-grained search of the fitness landscape...
- Persistence of motor adaptation during constrained, multi-joint, arm movements
R A Scheidt
Department of Biomedical Engineering, Northwestern University, Evanston, IL 60622, USA
J Neurophysiol 84:853-62. 2000
- Task difficulty and performance induce diverse adaptive patterns in gain and shape of primary auditory cortical receptive fields
Neuroscience and Cognitive Sciences Program, University of Maryland, College Park, MD 20742, USA
Neuron 61:467-80. 2009
..These adaptive STRF changes were largest in high-performance sessions, confirming a close correlation with behavior...
- Long-term experimental evolution in Escherichia coli. XI. Rejection of non-transitive interactions as cause of declining rate of adaptation
J Arjan G M de Visser
Laboratory of Genetics, Wageningen University, Arboretumlaan 4, 6703 BD Wageningen, The Netherlands
BMC Evol Biol 2:19. 2002
..Alternatively, this deceleration might be caused by non-transitive competitive interactions, in particular such that the measured advantage of later genotypes relative to earlier ones would be greater if they competed directly...
- Evolution of a polyphenism by genetic accommodation
Department of Biology, Duke University, Durham, NC 27708, USA
Science 311:650-2. 2006
..Evidently, mechanisms that regulate developmental hormones can mask genetic variation and act as evolutionary capacitors, facilitating the origin of novel adaptive phenotypes...
- Adaptations to submarine hydrothermal environments exemplified by the genome of Nautilia profundicola
Barbara J Campbell
University of Delaware, Lewes, Delaware, USA
PLoS Genet 5:e1000362. 2009
- The rise and fall of mutator bacteria
E9916, , , , 156 rue de Vaugirard, 75015 Paris, France
Curr Opin Microbiol 4:582-5. 2001
..The evolution of bacterial populations may happen through alternating periods of high and low mutation rates. The cost and benefits of high mutation rates in the course of bacterial adaptive evolution are reviewed...
- What can we learn from resource pulses?
Louie H Yang
Section of Evolution and Ecology, University of California, One Shields Avenue, Davis, California 95616, USA
Ecology 89:621-34. 2008
..We suggest that the study of resource pulses provides opportunities to understand the dynamics of many specific systems, and may also contribute to broader ecological questions at individual, population, and community levels...
- Orientation-specific adaptation in human visual cortex
Geoffrey M Boynton
The Salk Institute, La Jolla, California 92037 1099, USA
J Neurosci 23:8781-7. 2003
- Physiological bases of mosquito ecology
Institute of Zoology, , Winterthurerstr. 190, , Switzerland
J Vector Ecol 28:1-11. 2003
..These studies led to the recognition of distinctly different physiological strategies, for which the term "physiotype" has been coined, providing a basis for understanding the different ecotypes...
- Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival
Servicio de Micologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Carretera Majadahonda Pozuelo, Km 2, Majadahonda, 28220, Madrid, Spain
Cell Microbiol 10:2043-57. 2008
..neoformans cells produced resistance to phagocytosis. Our results suggest that capsular enlargement is a mechanism that enhances C. neoformans survival when ingested by phagocytic cells...
- The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast
Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA
PLoS Genet 4:e1000303. 2008
..Thus, in addition to answering basic mechanistic questions about evolutionary mechanisms, our work suggests that experimental evolution can also shed light on the function and regulation of individual metabolic pathways...
- Altered levels of proline dehydrogenase cause hypersensitivity to proline and its analogs in Arabidopsis
Vakgroep Moleculaire Genetica, Departement Plantengenetica, Vlaams Interuniversitair Instituut voor Biotechnologie, Universiteit Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium
Plant Physiol 128:73-83. 2002
..These findings demonstrate that altered At-PDH levels lead to weakly modified free Pro accumulation with a limited impact on plant development and growth, suggesting a tight control of Pro homeostasis and/or gene redundancy...
- Neuroimaging studies of priming
R N A Henson
Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, UK
Prog Neurobiol 70:53-81. 2003
..Interpretation of the findings is not always clear-cut, however, given potential confounding factors such as explicit memory, and several recommendations are made for future neuroimaging studies of priming...
- Response of plant metabolism to too little oxygen
Max Planck Institute of Molecular Plant Physiology, Am Muhlenberg 1, 14476 Golm, Germany
Curr Opin Plant Biol 6:247-56. 2003
..Recently, advances have been made in elucidating possible oxygen-sensing systems and regulatory components that are involved in these responses...
- Reach adaptation: what determines whether we learn an internal model of the tool or adapt the model of our arm?
Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
J Neurophysiol 100:1455-64. 2008
..Gradual changes in the tool's dynamics increased the extent to which the nervous system recalibrated the model of the subject's own arm...
- A systems view of nitrogen nutrient and metabolite responses in Arabidopsis
Elena A Vidal
Departamento de Genetica Molecular y Microbiologia, Pontificia Universidad Catolica de Chile, Alameda 340, Santiago, Chile
Curr Opin Plant Biol 11:521-9. 2008
..We discuss recent advances in this direction...
- African cichlid fish: a model system in adaptive radiation research
Department of Aquatic Ecology and Evolution, Institute of Zoology, University of Bern, Switzerland
Proc Biol Sci 273:1987-98. 2006
- HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia
Jung whan Kim
Graduate Program of Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Cell Metab 3:177-85. 2006
..These studies reveal a hypoxia-induced metabolic switch that shunts glucose metabolites from the mitochondria to glycolysis to maintain ATP production and to prevent toxic ROS production...
- Prism adaptation can improve contralesional tactile perception in neglect
Institute of Cognitive Neuroscience, University College, London, UK
Neurology 60:1829-31. 2003
..This finding suggests a potential role for prismatic adaptation in the rehabilitation of multiple sensory modalities in patients with neglect...
- Prism adaptation in the rehabilitation of patients with visuo-spatial cognitive disorders
INSERM, U 534, Espace et Action, Bron, France
Curr Opin Neurol 19:534-42. 2006
..The use of prism adaptation therapy in neglect and other visuo-spatial disorders has just started to reveal its potential, both at a practical and theoretical level...
- Adaptation and incipient sympatric speciation of Bacillus simplex under microclimatic contrast at "Evolution Canyons" I and II, Israel
Institute of Evolution, International Graduate Center of Evolution, University of Haifa, Haifa 31905, Israel
Proc Natl Acad Sci U S A 102:15924-9. 2005
..We conclude that, despite different biology, prokaryotes, like sexually reproducing eukaryotes, may consist of true species and parallel ecological speciation in eukaryotes...
- Prism adaptation and unilateral neglect: review and analysis
Gordon M Redding
Department of Psychology, Illinois State University, Campus Box 4620, Normal, IL 61790 4620, USA
Neuropsychologia 44:1-20. 2006
..Investigation of therapeutic prism adaptation requires methods that permit identification of both the calibration dysfunction and ameliorating realignment...
- A mutant of the Arabidopsis phosphate transporter PHT1;1 displays enhanced arsenic accumulation
Departamento de Genética Molecular de Plantas, Centro Nacional de Biotecnologia, Consejo Superior de Investigaciones Cientificas, Cantoblanco, E 28049 Madrid, Spain
Plant Cell 19:1123-33. 2007
..Furthermore, the repression effect of As(V) on Pi starvation responses may reflect a regulatory mechanism to protect plants from the extreme toxicity of arsenic...
- Decreasing xanthine oxidase-mediated oxidative stress prevents useful cellular adaptations to exercise in rats
Mari Carmen Gomez-Cabrera
Catholic University of Valencia, Spain
J Physiol 567:113-20. 2005
- Long-lasting amelioration of visuospatial neglect by prism adaptation
Dipartimento di Psicologia, Universita degli Studi di Bologna, Bologna, Italy
Brain 125:608-23. 2002
..In conclusion, these findings show that prism adaptation is a productive way of achieving long-lasting improvements in neglect treatment...
- Parallel genetic evolution within and between bacteriophage species of varying degrees of divergence
Jonathan P Bollback
Department of Biology, University of Copenhagen, Copenhagen, Denmark
Genetics 181:225-34. 2009
- Odorant-specific adaptation pathways generate olfactory plasticity in C. elegans
H A Colbert
Department of Anatomy, University of California, San Francisco 94143 0452, USA
Neuron 14:803-12. 1995
..Mutations in adp-1 and osm-9 do not diminish the ability of unadapted animals to respond to odorants, indicating that odorant sensation and odorant adaptation are distinct processes...
- Minimal models of adapted neuronal response to in vivo-like input currents
Giancarlo La Camera
Institute of Physiology, University of Bern, CH 3012 Bern, Switzerland
Neural Comput 16:2101-24. 2004
..Finally, we show how the stationary model can be used to predict the time-varying activity of a large population of adapting neurons...
- Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
Dana Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
Cell 119:121-35. 2004
..These data illustrate a central role for PGC-1alpha in the control of energy metabolism but also reveal novel systemic compensatory mechanisms and pathogenic effects of impaired energy homeostasis...
- The dynamics of adaptation on correlated fitness landscapes
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
Proc Natl Acad Sci U S A 106:18638-43. 2009
..Applying these methods to data from a long-term experiment, we infer the sign and strength of epistasis among beneficial mutations in the Escherichia coli genome...
- Evolution of metal hyperaccumulation required cis-regulatory changes and triplication of HMA4
Max Planck Institute of Molecular Plant Physiology, D 14476 Potsdam, Germany
Nature 453:391-5. 2008
..The elucidation of a natural strategy for metal hyperaccumulation enables the rational design of technologies for the clean-up of metal-contaminated soils and for bio-fortification...
- Gene networks involved in drought stress response and tolerance
RIKEN Plant Science Center, 1 7 22 Suehiro cho, Tsurumi ku, Yokohama, 203 0045 Japan
J Exp Bot 58:221-7. 2007
..A description is also provided of how various genes involved in stress tolerance were applied in genetic engineering of dehydration stress tolerance in transgenic Arabidopsis plants...
- Task-modulated "what" and "where" pathways in human auditory cortex
Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, CNY 149 13th Street, Charlestown, MA 02129, USA
Proc Natl Acad Sci U S A 103:14608-13. 2006
..This finding suggests that selective-attention effects are feature-specific in the human nonprimary auditory cortex and that they arise from enhanced tuning of receptive fields of task-relevant neuronal populations...
- Short on phosphate: plant surveillance and countermeasures
Carla A Ticconi
Department of Plant Sciences, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA
Trends Plant Sci 9:548-55. 2004
..Recent studies have provided evidence for P(i) as a signaling molecule and initial insight into the coordination of P(i) deficiency responses at the cellular and molecular level...
- From molecular noise to behavioural variability in a single bacterium
The Institute for Biophysical Dynamics and the James Franck Institute, The University of Chicago, 5640 South Ellis Avenue, Chicago, Illinois 60637, USA
Nature 428:574-8. 2004
..Small changes in the concentration of one key network component suppress temporal behavioural variability, suggesting that such variability is a selected property of this adaptive system...
- Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress
Miriam J Hercus
Aarhus Centre for Environmental Stress Research, Department of Ecology and Genetics, University of Aarhus, Ny Munkegade, Building 540, DK-8000 Aarhus C, Denmark
Biogerontology 4:149-56. 2003
..The mild heat stress had no impact on egg viability. The mild heat stress exposures increased resistance to potentially lethal heat stress and levels of Hsp70 expression in heat-exposed flies were higher than those in controls...
- Evidence of adaptive divergence in plasticity: density- and site-dependent selection on shade-avoidance responses in Impatiens capensis
Department of Ecology and Evolutionary Biology, Brown University, Providence, Rhode Island 02912, USA
Evolution 54:1956-68. 2000
..Selection on the measured characters contributed to local adaptation and fully accounted for fitness differences between populations in all treatments except the woodland site at natural density...
- Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptors
The Mary D Allen Laboratory for Vision Research, Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles 90089 9112, USA
Proc Natl Acad Sci U S A 98:9948-53. 2001
..We conclude that GCAPs strongly regulate GC activity in mouse rods, decreasing the flash sensitivity in darkness and increasing the incremental flash sensitivity in bright steady light, thereby extending the rod's operating range...
- Representation of perceived object shape by the human lateral occipital complex
Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Science 293:1506-9. 2001
..These data indicate that the LOC represents not simple image features, but rather higher level shape information...
- Recalibration of perceived time across sensory modalities
James V M Hanson
Department of Optometry, University of Bradford, Richmond Road, Bradford BD7 1DP, UK
Exp Brain Res 185:347-52. 2008
..In light of these findings we suggest that a single supramodal mechanism may be responsible for the observed recalibration of multisensory perceived time...
- Shifting and scaling adaptation to dynamic stimuli in somatosensory cortex
J A Garcia-Lazaro
Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Building, Parks Road, Oxford, OX13PT, UK
Eur J Neurosci 26:2359-68. 2007
..Using realistic single-neuron models, we go on to show that after-hyperpolarizing currents, such as those carried by K(Ca)(2+) channels, may be responsible for the threshold shifts, but not the slope changes...
- Population genomics of marine fishes: identifying adaptive variation in space and time
Einar E Nielsen
Technical University of Denmark, National Institute of Aquatic Resources, Vejlsøvej 39, Silkeborg, Denmark
Mol Ecol 18:3128-50. 2009
- Mechanisms of plant desiccation tolerance
F A Hoekstra
Graduate School Experimental Plant Sciences, Laboratory of Plant Physiology, Wageningen University, Arboretumlaan 4, 6703 BD Wageningen, The Netherlands
Trends Plant Sci 6:431-8. 2001
- Regulation of the Arabidopsis transcriptome by oxidative stress
Centre for Research in Plant Science, University of the West of England, Bristol, Coldharbour Lane, Bristol BS16 1QY, United Kingdom
Plant Physiol 127:159-72. 2001
- Costs and benefits of high mutation rates: adaptive evolution of bacteria in the mouse gut
E9916, , , , 156 rue de Vaugirard, 75015 Paris, France
Science 291:2606-8. 2001
..The short-term advantages and long-term disadvantages of mutator bacteria could account for their frequency in nature...
- The stroke volume response during or throughout 4-8 min of constant-power exercise that elicits VO2max
Edward F Coyle
J Appl Physiol 104:282-3; author reply 284-5. 2008
- Solving the Fick principle using whole body measurements can be used to discriminate ''central'' and ''peripheral'' adaptations to training
Frederic N Daussin
Eur J Appl Physiol 103:733-5; author reply 737-8. 2008
- American College of Sports Medicine position stand. Progression models in resistance training for healthy adults
William J Kraemer
Med Sci Sports Exerc 34:364-80. 2002
..In the interpretation of this position stand, as with prior ones, the recommendations should be viewed in context of the individual's target goals, physical capacity, and training status...
- Post-exercise leg and forearm flexor muscle cooling in humans attenuates endurance and resistance training effects on muscle performance and on circulatory adaptation
Laboratory for Exercise Physiology and Biomechanics, Chukyo University, 101 Tokodachi, Kaizu cho Toyota, 470 0393, Aichi, Japan
Eur J Appl Physiol 96:572-80. 2006
..This seems disadvantageous for training, in contrast to the beneficial combination of rest, ice, compression and elevation in the treatment of macroscopic musculo-tendinous damage...
- Control of heart rate variability by cardiac parasympathetic nerve activity during voluntary static exercise in humans with tetraplegia
Dept of Sports Medicine, Graduate School of Health Sciences, Hiroshima University, Minami Ku, Hiroshima 734 8551, Japan
J Appl Physiol 103:1669-77. 2007
- Effect of endurance exercise training on Ca2+ calmodulin-dependent protein kinase II expression and signalling in skeletal muscle of humans
Adam J Rose
Copenhagen Muscle Research Centre, Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Universitetsparken 13, Copenhagen, Denmark 2100
J Physiol 583:785-95. 2007
..This may contribute to greater Ca(2+) mediated regulation during exercise and the altered muscle phenotype with training...
- Despite the large quantity of data on LV performance during exercise, basic data on left ventricular performance are conflicting
J Appl Physiol 104:281-2; author reply 284-5. 2008
- Prolonged electrical muscle stimulation exercise improves strength and aerobic capacity in healthy sedentary adults
Department of Academic Cardiology, University of Hull, Castle Hill Hospital, Cottingham, Kingston-upon-Hull, UK
J Appl Physiol 99:2307-11. 2005
..05). These results suggest that EMS can be used in sedentary adults to improve physical fitness. It may provide a viable alternative to more conventional forms of exercise in this population...
- The occurrence of a VO2 drop after the achievement of a VO2 peak or VO2max plateau
Veronique Louise Billat
J Appl Physiol 104:283; author reply 284-5. 2008
- Endurance training, resistance training, body composition, or different disease states can lead to diverse adaptations in cardiac structure and/or function
Chantal A Vella
J Appl Physiol 104:282; author reply 284-5. 2008
- Point: Stroke volume does/does not decline during exercise at maximal effort in healthy individuals
Centre for Sports Medicine and Human Performance Brunel University, Uxbridge Middlesex, United Kingdom
J Appl Physiol 104:275-6; discussion 279-80. 2008
- PGC-1beta is downregulated by training in human skeletal muscle: no effect of training twice every second day vs. once daily on expression of the PGC-1 family
Ole Hartvig Mortensen
Centre of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet 7641, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
J Appl Physiol 103:1536-42. 2007
..In conclusion, there was no difference between training protocols on the acute exercise and training response of the PGC-1 family. However, training caused a decrease in PGC-1beta mRNA levels...
- Endurance performance is associated with the heart capacity to pump large blood volume to muscles
Pierre Marie Lepretre
J Appl Physiol 104:281; author reply 284-5. 2008
- Decrease or no decrease in the stroke volume of healthy humans approaching volitional exhaustion during large muscle mass exercise
J Appl Physiol 104:281; author reply 284-5. 2008
- Counterpoint: Stroke volume does not decline during exercise at maximal effort in healthy individuals
Darren E R Warburton
Cardiovascular Physiology and Rehabilitation Laboratory, Experimental Medicine Program, Faculty of Medicine, University of British Columbia, Vancouver, Canada
J Appl Physiol 104:276-8; discussion 278-9. 2008
- The effects of creatine supplementation on cardiovascular, metabolic, and thermoregulatory responses during exercise in the heat in endurance-trained humans
L P Kilduff
Centre for Exercise Science and Medicine in the Institute of Biomedical and Life Sciences at the University of Glasgow, Glasgow, UK
Int J Sport Nutr Exerc Metab 14:443-60. 2004
..3 +/- 4.9 min vs. 51.7 +/- 7.4 min, P = 0.031). Cr-induced hyperhydration can result in a more efficient thermoregulatory response during prolonged exercise in the heat...
- The concept of maximal lactate steady state: a bridge between biochemistry, physiology and sport science
Veronique L Billat
Sport Science Department, University of Evry Val d Essonne, Paris, France
Sports Med 33:407-26. 2003
..However, lactate exchange and removal indirectly estimated with velocity constants of the individual blood lactate recovery has been reported to be related to time to exhaustion at maximal oxygen uptake...
- Resistance exercise training reduces plasma endothelin-1 concentration in healthy young humans
Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki, Japan
J Cardiovasc Pharmacol 44:S443-6. 2004
- Effects of chronic NaHCO3 ingestion during interval training on changes to muscle buffer capacity, metabolism, and short-term endurance performance
School of Human Movement and Exercise Science, The University of Western Australia, Perth, Australia
J Appl Physiol 101:918-25. 2006
- Cost of transport is increased after cold exposure in Monodelphis domestica: training for inefficiency
Paul J Schaeffer
Department of Biological Sciences, Physiology and Functional Morphology Group, Northern Arizona University, Flagstaff, AZ 86011, USA
J Exp Biol 208:3159-67. 2005
..However, linked to the dramatic shift in muscle properties is an equally dramatic increase in whole animal muscle energetics during locomotion, suggesting an uncoupled state, or 'training for inefficiency'...
- Long-term fat diet adaptation effects on performance, training capacity, and fat utilization
Jørn Wulff Helge
Copenhagen Muscle Research Centre, H S State Hospital, Blegdamsvej 9, DK 2100 Copenhagen Ø, Denmark
Med Sci Sports Exerc 34:1499-504. 2002
- The Yo-Yo intermittent recovery test : a useful tool for evaluation of physical performance in intermittent sports
Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen Muscle Research Centre, Copenhagen, Denmark
Sports Med 38:37-51. 2008
..The Yo-Yo IR tests provide a simple and valid way to obtain important information of an individual's capacity to perform repeated intense exercise and to examine changes in performance...
- Nonexercise activity thermogenesis (NEAT): environment and biology
James A Levine
Endocrine Research Unit, Mayo Clinic, Rochester, MN 55905, USA
Am J Physiol Endocrinol Metab 286:E675-85. 2004
..A scheme is described in this review in which NEAT corresponds to a carefully regulated "tank" of physical activity that is crucial for weight control...
- Regulation of mTOR by amino acids and resistance exercise in skeletal muscle
Institut d éducation physique et de réadaptation, Universite Catholique de Louvain, Belgium
Eur J Appl Physiol 94:1-10. 2005
..There appears to be a requirement for a minimal concentration of plasma insulin to stimulate muscle protein synthesis in response to resistance exercise and AA ingestion...
- Control of gene expression and mitochondrial biogenesis in the muscular adaptation to endurance exercise
Department of Biology, York University, Toronto, Ontario, Canada, M3J 1P3
Essays Biochem 42:13-29. 2006
..An understanding of how exercise can produce this effect could help us decide whether exercise is beneficial for patients suffering from mitochondrial disorders, as well as a variety of metabolic diseases...
- Reactive oxygen species and redox-regulation of skeletal muscle adaptations to exercise
Malcolm J Jackson
School of Clinical Sciences, University of Liverpool Division of Metabolic and Cellular Medicine Liverpool L69 3GA, UK
Philos Trans R Soc Lond B Biol Sci 360:2285-91. 2005
..These processes are also recognized to be modified during ageing and in some disease states, providing the potential that interventions affecting ROS activity may influence muscle function or viability in these situations...
- Interleukin-6 in acute exercise and training: what is the biological relevance?
Christian P Fischer
Centre of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet and Faculty of Health Sciences, University of Copenhagen, Denmark
Exerc Immunol Rev 12:6-33. 2006
..Accordingly, a decreased plasma IL-6 concentration at rest as well as in response to exercise appears to characterize normal training adaptation...
- Costs and benefits of cold acclimation in field-released Drosophila
Torsten N Kristensen
Department of Genetics and Biotechnology, University of Aarhus, P O Box 50, DK 8830 Tjele, Denmark
Proc Natl Acad Sci U S A 105:216-21. 2008
- Interactions between the direct and indirect effects of predators determine life history evolution in a killifish
Matthew R Walsh
Department of Biology, University of California, Riverside, CA 92521, USA
Proc Natl Acad Sci U S A 105:594-9. 2008
..Rivulus from sites with predators better exploit the higher resources in those habitats. Therefore, both direct and indirect effects of predators have evolutionary consequences...
- Daily delivery of dietary nitrogen to the periphery is stable in rats adapted to increased protein intake
Institut National de la Recherche Agronomique, , Institut National Agronomique de Paris-Grignon, F-75005 Paris, France
Am J Physiol Endocrinol Metab 281:E826-36. 2001
..Digestive kinetics and splanchnic anabolism participate to a lesser extent in the regulation processes...
- Exercise reduces arterial pressure augmentation through vasodilation of muscular arteries in humans
Dept of Clinical Pharmacology, St Thomas Hospital, Lambeth Palace Rd, London SE1 7EH, UK
Am J Physiol Heart Circ Physiol 294:H1645-50. 2008
..2 +/- 0.4 to 8.6 +/- 0.4 mm, P < 0.05). In conclusion, exercise dilates muscular arteries and reduces arterial pressure augmentation, an effect that will enhance ventricular-vascular coupling and reduce load on the left ventricle...
- Postactivation potentiation influences differently the nonlinear summation of contractions in young and elderly adults
Laboratory of Applied Biology, Universite Libre de Bruxelles, 28 Ave P Héger, CP 168, 1000 Brussels, Belgium
J Appl Physiol 98:1243-50. 2005
..This overall attenuation of potentiation with aging, however, appears to have a moderate influence on the decrement of the muscular performance...
- Acute effects of static stretching on passive stiffness of the hamstring muscles calculated using different mathematical models
Laboratoire Motricit, Interactions, Performance, JE 2438, UFR STAPS, , France
Clin Biomech (Bristol, Avon) 21:755-60. 2006
..INTERPRETATION: Stretching has significant effects on stiffness, but the findings highlight the need to carefully assess the effect of different models when analyzing such data...
- Modeling of muscle fatigue using Hill's model
C Y Tang
Department of Industrial and Systems Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, China
Biomed Mater Eng 15:341-8. 2005
..The effects of different shapes of the recovery curves have also been considered in this model. Validation of the model has been performed by comparing the predicted results with the experimental data from an existing literature...
- The effect of AMPD1 genotype on blood flow response to sprint exercise
Department of Laboratory Medicine, Division of Clinical Physiology, Karolinska Institute, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden
Eur J Appl Physiol 103:173-80. 2008
..8+/-1.1 min vs. 16.1+/-1.4 min, p<0.001). These results suggest a better circulatory adaptation to exercise in individuals with diminished mAMPD activity, probably due to an AMPD1 genotype-dependent increase in adenosine formation...
- 5'-AMP-activated protein kinase activity and protein expression are regulated by endurance training in human skeletal muscle
Copenhagen Muscle Research Centre, Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, DK 2100 Copenhagen, Denmark
Am J Physiol Endocrinol Metab 286:E411-7. 2004
..Except for the increase in gamma1 protein, all observed adaptations to training could be ascribed to local contraction-induced mechanisms, since they did not occur in the contralateral untrained muscle...
- Leg stiffness modulation during exhaustive stretch-shortening cycle exercise
Department of Biology of Physical Activity, Neuromuscular Research Center, University of Jyvaskyla, Jyvaskyla, Finland
Scand J Med Sci Sports 17:67-75. 2007
..It is suggested that efficient activity modulation (i.e. high EMG ratio) of the triceps surae muscle during an intensive fatiguing SSC exercise may postpone the exhaustion and development of metabolic fatigue...
- Voluntary activation and mechanical performance of human triceps surae muscle after exhaustive stretch-shortening cycle jumping exercise
Department of Biology of Physical Activity, University of Jyvaskyla, PO Box 35, FIN 40014 Jyvaskyla, Finland
Eur J Appl Physiol 91:538-44. 2004
..The magnitude of post exercise contractile and activation failure as well as the delayed recovery of neuromuscular performance may have been augmented in some subjects due to their high number of jumps in the exercise...