clinical pathology

Summary

Summary: A subspecialty of pathology applied to the solution of clinical problems, especially the use of laboratory methods in clinical diagnosis. (Dorland, 28th ed.)

Top Publications

  1. ncbi Measuring the significance of participant evaluation of acceptability of cases in the College of American Pathologists Interlaboratory Comparison Program in cervicovaginal cytology
    Andrew A Renshaw
    Department of Pathology, Baptist Hospital of Miami, Miami, FL, USA
    Arch Pathol Lab Med 129:1093-6. 2005
  2. ncbi Contributions of pathology and laboratory medicine to the patient safety movement
    Noubar Kessimian
    Department of Pathology, Memorial Hospital of Rhode Island, Pawtucket 02860, USA
    Med Health R I 88:216-9. 2005
  3. doi Specimen labeling errors: a Q-probes analysis of 147 clinical laboratories
    Elizabeth A Wagar
    Department of Pathology and Laboratory Medicine, University of California Los Angeles Clinical Laboratories, Los Angeles, CA 90095 1732, USA
    Arch Pathol Lab Med 132:1617-22. 2008
  4. ncbi Clinical pathology testing recommendations for nonclinical toxicity and safety studies. AACC-DACC/ASVCP Joint Task Force
    K Weingand
    Procter and Gamble Co, Miami Valley Laboratories, Cincinnati, Ohio 45239
    Toxicol Pathol 20:539-43. 1992
  5. ncbi Comprehensive graphic-based display of clinical pathology laboratory data
    John Bernard Henry
    Dept of Pathology, State University of New York, Upstate Medical University, 750 E Adams St, Syracuse, NY 13210, USA
    Am J Clin Pathol 119:330-6. 2003
  6. pmc Development and evaluation of the virtual pathology slide: a new tool in telepathology
    Sean S P Costello
    School of Biotechnology, Medical Informatics Group, Dublin City University, Dublin, Ireland
    J Med Internet Res 5:e11. 2003
  7. ncbi Consensus report of the task force on standardisation of DNA flow cytometry in clinical pathology. DNA Flow Cytometry Task Force of the European Society for Analytical Cellular Pathology
    M G Ormerod
    Department of Medical Radiobiology, Karolinska Institute, Stockholm, Sweden
    Anal Cell Pathol 17:103-10. 1998
  8. ncbi Application of virtual microscopy in clinical cytopathology
    D M Steinberg
    The John K. Frost Cytopathology Laboratory, Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland, USA
    Diagn Cytopathol 25:389-96. 2001
  9. ncbi Digital storage of glass slides for quality assurance in histopathology and cytopathology
    Francesca Demichelis
    ITC irst, Telemedicine and Medical Informatics Laboratory, Trento, Italy
    J Telemed Telecare 8:138-42. 2002
  10. pmc Development of visual diagnostic expertise in pathology -- an information-processing study
    Rebecca S Crowley
    Center for Pathology Informatics, Center for Biomedical Informatics, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Am Med Inform Assoc 10:39-51. 2003

Detail Information

Publications175 found, 100 shown here

  1. ncbi Measuring the significance of participant evaluation of acceptability of cases in the College of American Pathologists Interlaboratory Comparison Program in cervicovaginal cytology
    Andrew A Renshaw
    Department of Pathology, Baptist Hospital of Miami, Miami, FL, USA
    Arch Pathol Lab Med 129:1093-6. 2005
    ..The quality of gynecologic cytology slides within educational and proficiency testing programs may deteriorate during use. Participant evaluation of the acceptability of these slides subsequent to possible deterioration is not known...
  2. ncbi Contributions of pathology and laboratory medicine to the patient safety movement
    Noubar Kessimian
    Department of Pathology, Memorial Hospital of Rhode Island, Pawtucket 02860, USA
    Med Health R I 88:216-9. 2005
  3. doi Specimen labeling errors: a Q-probes analysis of 147 clinical laboratories
    Elizabeth A Wagar
    Department of Pathology and Laboratory Medicine, University of California Los Angeles Clinical Laboratories, Los Angeles, CA 90095 1732, USA
    Arch Pathol Lab Med 132:1617-22. 2008
    ..Specimen identification errors have been reported to occur at rates of 0.1% to 5%...
  4. ncbi Clinical pathology testing recommendations for nonclinical toxicity and safety studies. AACC-DACC/ASVCP Joint Task Force
    K Weingand
    Procter and Gamble Co, Miami Valley Laboratories, Cincinnati, Ohio 45239
    Toxicol Pathol 20:539-43. 1992
    b>Clinical pathology testing in nonclinical toxicity and safety studies is an important part of safety assessment. In recent years, clinical laboratory testing has rapidly expanded and improved...
  5. ncbi Comprehensive graphic-based display of clinical pathology laboratory data
    John Bernard Henry
    Dept of Pathology, State University of New York, Upstate Medical University, 750 E Adams St, Syracuse, NY 13210, USA
    Am J Clin Pathol 119:330-6. 2003
    ..with clinician perception and ease of data interpretation in redesigning the graphic reporting of numeric clinical pathology laboratory data...
  6. pmc Development and evaluation of the virtual pathology slide: a new tool in telepathology
    Sean S P Costello
    School of Biotechnology, Medical Informatics Group, Dublin City University, Dublin, Ireland
    J Med Internet Res 5:e11. 2003
    ..This permits a pathologist to navigate to any area on a slide, at any magnification, similar to a conventional microscope...
  7. ncbi Consensus report of the task force on standardisation of DNA flow cytometry in clinical pathology. DNA Flow Cytometry Task Force of the European Society for Analytical Cellular Pathology
    M G Ormerod
    Department of Medical Radiobiology, Karolinska Institute, Stockholm, Sweden
    Anal Cell Pathol 17:103-10. 1998
    Guidelines are given to assist the standardisation of DNA flow cytometry in clinical pathology. They have been agreed by a group of twelve scientists from nine European countries.
  8. ncbi Application of virtual microscopy in clinical cytopathology
    D M Steinberg
    The John K. Frost Cytopathology Laboratory, Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland, USA
    Diagn Cytopathol 25:389-96. 2001
    ..Shortcomings include 1) expensive initial setup, 2) inability to maintain an adequate focus in a thick smear with multiple levels, 3) large storage size of the VM slide, and 4) relatively long time needed to scan a slide...
  9. ncbi Digital storage of glass slides for quality assurance in histopathology and cytopathology
    Francesca Demichelis
    ITC irst, Telemedicine and Medical Informatics Laboratory, Trento, Italy
    J Telemed Telecare 8:138-42. 2002
    ..Use of virtual slides should encourage the diffusion of national quality assurance programmes, which at present suffer from certain organizational and logistical limitations...
  10. pmc Development of visual diagnostic expertise in pathology -- an information-processing study
    Rebecca S Crowley
    Center for Pathology Informatics, Center for Biomedical Informatics, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Am Med Inform Assoc 10:39-51. 2003
    ..To identify key features contributing to trainees' development of expertise in microscopic pathology diagnosis, a complex visual task, and to provide new insights to help create computer-based training systems in pathology...
  11. ncbi The role of the pathologist as tissue refiner and data miner: the impact of functional genomics on the modern pathology laboratory and the critical roles of pathology informatics and bioinformatics
    M J Becich
    Center for Pathology Informatics, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center Health System, Pittsburgh, PA 15232, USA
    Mol Diagn 5:287-99. 2000
    ....
  12. ncbi Comparative genomic hybridization arrays in clinical pathology: progress and challenges
    Shelly R Gunn
    Department of Pathology, University of Texas Health Science Center, San Antonio, Texas 78229 3900, USA
    Mol Diagn Ther 11:73-7. 2007
    ..In this article, we share some of our experiences with diagnostic array CGH and discuss recent progress and challenges involved with the integration of array CGH into clinical laboratory medicine...
  13. ncbi Saliva and the clinical pathology laboratory
    Michael A Pesce
    Department of Pathology, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    Ann N Y Acad Sci 1098:192-9. 2007
    ..These tests fall into multiple clinical pathology disciplines, including clinical chemistry, hematology, coagulation, transfusion medicine, microbiology, ..
  14. ncbi The impact of molecular diagnostic tests on patient outcomes
    J S Ross
    Department of Pathology and Laboratory Medicine, Albany Medical College, New York, USA
    Clin Lab Med 19:815-31, vi-vii. 1999
    ..In this review, the financial and patient care determinants of outcomes for molecular-based testing of disease predisposition, screening, early detection, and directed therapy are presented...
  15. ncbi Resident physician opinions on autopsy importance and procurement
    Mindy J Hull
    Department of Pathology and Laboratory Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    Hum Pathol 38:342-50. 2007
    ..Improving autopsy education, enhancing availability of resources, and strengthening the pathologist-internist collaboration may serve to heighten awareness and ultimately procurement...
  16. ncbi Automated clinical annotation of tissue bank specimens
    John R Gilbertson
    Center for Pathology Informatics, Department of Pathology, Benedum Oncology Informatics Center, University Cancer Institute, University of Pittsburgh Medical School, 5150 Centre Avenue, Pittsburgh, PA 15232, USA
    Stud Health Technol Inform 107:607-10. 2004
    ..The result has been much more extensive and accurate initial tissue annotation with less effort in the tissue bank, as well as dynamic ongoing annotation as the cancer registry follows patients over time...
  17. ncbi The integration of molecular diagnostics with therapeutics. Implications for drug development and pathology practice
    Jeffrey S Ross
    Dept of Pathology and Laboratory Medicine, Albany Medical College, Albany, NY 12208, USA
    Am J Clin Pathol 119:26-36. 2003
    ....
  18. ncbi The development and evaluation of the UK national telepathology network
    W M Bamford
    Department of Histopathology, Leicester Royal Infirmary, UK
    Histopathology 42:110-9. 2003
    ..Arguing that the value of a network increases as more people are connected, we sought to install a simple, low-cost telepathology system into any histopathology laboratory which requested it within the UK...
  19. ncbi Pathologists' attitudes to implementing telepathology
    T Mairinger
    Department of Pathology, University of Innsbruck, Austria
    J Telemed Telecare 4:41-6. 1998
    ..Teleteaching and teletraining were seen as welcome additional techniques, but were nevertheless judged unable to replace classical methods of teaching and training...
  20. ncbi Errors in pathology and laboratory medicine: consequences and prevention
    Sandra C Hollensead
    Department of Pathology and Laboratory Medicine, University of Louisville SOM, Louisville, Kentucky 40202, USA
    J Surg Oncol 88:161-81. 2004
    ..Seven recommendations are made to reduce errors in future for Pathology and Laboratory Medicine...
  21. ncbi Leukemia/lymphoma in cerebrospinal fluid: distinguishing between cases that performed well and poorly in the College of American Pathologists Interlaboratory Comparison Program in Non-gynecologic Cytology
    Andrew A Renshaw
    Department of Pathology, Baptist Hospital of Miami, Miami, Fla, USA
    Arch Pathol Lab Med 130:1762-5. 2006
    ..Although the cytologic features of leukemia/lymphoma in cerebrospinal fluid specimens are well known, the correlation of these features with the ability of cytologists to identify this tumor have not been well studied...
  22. ncbi Papanicolaou tests with mixed high-grade and low-grade squamous intraepithelial lesion features: distinct performance in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal Cytopathology
    Andrew A Renshaw
    Department of Pathology, Baptist Hospital of Miami, Miami, FL, USA
    Arch Pathol Lab Med 130:456-9. 2006
    ..The performance of cases with mixed LSIL and HSIL features is unknown...
  23. ncbi The potential for failure in gynecologic regulatory proficiency testing with current slide validation criteria: results from the College of American Pathologists Interlaboratory Comparison in Gynecologic Cytology Program
    Nancy A Young
    Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Arch Pathol Lab Med 130:1114-8. 2006
    ..Current regulatory proficiency testing scoring results in an automatic failure for identifying high-grade squamous intraepithelial lesion (HSIL) as negative...
  24. ncbi Pap test discrepancies and follow-up histology
    Edward B Stelow
    Department of Pathology and Laboratory Medicine, University of Minnesota, Minneapolis, Minnesota 55415, USA
    Diagn Cytopathol 29:111-5. 2003
    ..This suggests that discrepancy data may be helpful for evaluating the performance of both CPs and CTs. It may also be of educational use for both CPs and CTs to know the follow-up histology in these cases...
  25. ncbi Interlaboratory reproducibility of atypical squamous cells of undetermined significance report: a national survey
    M Confortini
    Analytical and Biomolecular Cytology Unit, Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Cytopathology 14:263-8. 2003
    ....
  26. ncbi Robustness of validation criteria in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal Cytology
    Andrew A Renshaw
    Department of Pathology, Baptist Hospital of Miami, Miami, Fla, USA
    Arch Pathol Lab Med 130:1119-22. 2006
    ..Although the precision of diagnoses in peer-reviewed educational programs has been examined, the robustness of the validation criteria for specific types of interpretations used in proficiency testing has not been previously studied...
  27. ncbi Significance of field validation in the interlaboratory comparison program in cervicovaginal cytology
    Dwight K Oxley
    Arch Pathol Lab Med 130:144; author reply 144-5. 2006
  28. ncbi Cytologic features of squamous cell carcinoma in conventional smears: comparison of cases that performed poorly with those that performed well in the College of American Pathologists Interlaboratory Comparison Program in cervicovaginal cytology
    Andrew A Renshaw
    Department of Pathology, Baptist Hospital of Miami, Miami, FL 33176 2197, USA
    Arch Pathol Lab Med 129:1097-9. 2005
    ....
  29. ncbi [Procedure for accurate evaluation of laboratory data and its international trends]
    Katsuhiko Kuwa
    Graduate School of Comprehensive Human Sciences Institute of Clinical Medicine, University of Tsukuba, Tsukuba, 305 8575
    Rinsho Byori 53:531-9. 2005
    ..As the results, the work of the standardization based on reliability such as validation of reagent's kits and the measured values and uncertainty evaluation would be internationally advanced...
  30. ncbi Measuring the significance of field validation in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal Cytology: how good are the experts?
    Andrew A Renshaw
    Department of Pathology, Baptist Hospital of Miami, Miami, Fla, USA
    Arch Pathol Lab Med 129:609-13. 2005
    ..However, the reliability of expert opinion alone in selecting slides of a specific cytodiagnosis that can be reproducibly and reliably identified by subsequent reviewers has not been determined...
  31. ncbi Cytologic features of adenocarcinoma, not otherwise specified, in conventional smears: comparison of cases that performed poorly with those that performed well in the College of American Pathologists Interlaboratory Comparison Program in cervicovaginal cy
    Andrew A Renshaw
    Department of Pathology, Baptist Hospital of Miami, Miami, FL 33176 2197, USA
    Arch Pathol Lab Med 130:23-6. 2006
    ....
  32. ncbi Laboratory accreditation and inspection
    Carol A Rauch
    Department of Pathology, Baystate Health, 759 Chestnut Street, Springfield, MA 01199, USA
    Clin Lab Med 27:845-58, vii. 2007
    ....
  33. ncbi [How can we contribute to Yamagata University Hospital as clinical laboratory physicians?]
    Masahiko Igarashi
    Department of Laboratory Medicine, Yamagata University School of Medicine, Yamagata 990 9585
    Rinsho Byori 56:689-95. 2008
    ..Therefore, our clinical laboratory physicians should play a central role to guarantee the specified health checkup system...
  34. pmc Development and preliminary evaluation of the VPS ReplaySuite: a virtual double-headed microscope for pathology
    Dan J Johnston
    Medical Informatics Group, School of Biotechnology, Dublin City University, Dublin, Ireland
    BMC Med Inform Decis Mak 5:10. 2005
    ..Limited emphasis has been placed on analysing the diagnostic process used by pathologists to reach a diagnosis and using this as a resource for improving diagnostic performance...
  35. ncbi Errors in laboratory medicine: practical lessons to improve patient safety
    Peter J Howanitz
    Department of Pathology, State University of New York Downstate, Brooklyn, NY 11203, USA
    Arch Pathol Lab Med 129:1252-61. 2005
    ..Error rates in laboratory practices are collected routinely for a variety of performance measures in all clinical pathology laboratories in the United States, but a list of critical performance measures has not yet been recommended...
  36. ncbi Quality assurance in gynecologic cytology. The value of cytotechnologist-cytopathologist discrepancy logs
    E S Cibas
    Dept of Pathology, Brigham and Women's Hospital, 75 Francis St, Boston, MA, USA
    Am J Clin Pathol 115:512-6. 2001
    ..Measures of CT-CP diagnostic concordance are a useful and efficient measure of CT performance and can be incorporated into mandatory semiannual performance evaluations...
  37. ncbi Cytopathology in Slovenia
    Z Pohar-Marinsek
    Department of Cytopathology, Institute of Oncology, Zaloska, Ljubljana, Slovenia
    Cytopathology 15:53-7. 2004
    ..6/100 000 in the year 2000. The mortality rate has remained roughly constant at 5-7/100 000 for the last 20 years. During the last few years quality assurance measures have been taken for improving the performance in cervical cytology...
  38. ncbi Comparison of cytology proficiency testing: glass slides vs. virtual slides
    MariBeth Gagnon
    Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
    Acta Cytol 48:788-94. 2004
    ..To compare proficiency testing in gynecologic cytology using glass slides vs. virtual slides...
  39. ncbi Assessment monitoring of laboratory critical values: a College of American Pathologists Q-Tracks study of 180 institutions
    Elizabeth A Wagar
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, 90095 1732, USA
    Arch Pathol Lab Med 131:44-9. 2007
    ..Critical laboratory value reporting is a highly visible and essential key activity for clinical laboratories...
  40. ncbi Overview of the laboratory accreditation programme of the College of American Pathologists
    K K Abu-Amero
    Molecular Genetics and DNA Diagnostics Laboratory, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    East Mediterr Health J 8:654-63. 2002
    ..This article gives an insight into the current situation of laboratory accreditation in Saudi Arabia and an updated overview of the process involved in obtaining laboratory accreditation from the College of American Pathologists...
  41. ncbi Improvements to the CAP Laboratory Accreditation Program
    R Bruce Williams
    College of American Pathologists Commission on Laboratory Accreditation, USA
    Clin Leadersh Manag Rev 20:E4. 2006
  42. ncbi The Indonesian society of clinical pathologist external quality assessment program (ISCP-EQAP) in clinical chemistry
    M Suryaatmadja
    Department of Clinical Pathology, Faculty of Medicine University of Indonesia, Dr Cipto Mangunkusmo General Hospital, Jakarta, Indonesia
    Southeast Asian J Trop Med Public Health 33:44-5. 2002
  43. ncbi Speak out for quality pathology and laboratory medicine
    David F Keren
    ASCP, USA
    Am J Clin Pathol 122:314. 2004
  44. ncbi [CAP quality management system in clinical laboratory and its issue]
    Hiromitsu Tazawa
    SBS, Inc, Sagamihara 229 1125
    Rinsho Byori 52:266-9. 2004
    ....
  45. ncbi Detecting and preventing the occurrence of errors in the practices of laboratory medicine and anatomic pathology: 15 years' experience with the College of American Pathologists' Q-PROBES and Q-TRACKS programs
    David A Novis
    Department of Pathology, Wentworth Douglass Hospital, Dover, NH 03820, USA
    Clin Lab Med 24:965-78. 2004
    ....
  46. ncbi Review of Penner's criteria for proficiency testing in cytopathology: implications for the redesign of the federally mandated proficiency testing in cytopathology
    George K Nagy
    Division of Molecular Medicine, Cytopathology Laboratory, Wadsworth Center, New York State Department of Health, Empire State Plaza, Albany, New York 12201 0509, USA
    Diagn Cytopathol 35:61-4. 2007
    ..The revised criteria should be taken into consideration in the planned technical redesign of the nationwide PTC...
  47. ncbi Interobserver agreement on microfollicles in thyroid fine-needle aspirates
    Andrew A Renshaw
    Department of Pathology, Baptist Hospital of Miami, Miami, FL 33176 2197, USA
    Arch Pathol Lab Med 130:148-52. 2006
    ..Although microfollicles are a well-known feature of follicular neoplasms in fine-needle aspirates of the thyroid, the level of agreement about classifying groups as microfollicles is not known...
  48. ncbi Q-tracks: a College of American Pathologists program of continuous laboratory monitoring and longitudinal tracking
    Richard J Zarbo
    Department of Pathology, Henry Ford Hospital, Detroit, Mich 48202, USA
    Arch Pathol Lab Med 126:1036-44. 2002
    ....
  49. ncbi Assessment of interlaboratory variation in the immunohistochemical determination of estrogen receptor status using a breast cancer tissue microarray
    Robin L Parker
    Department of Pathology, Vancouver Hospital and University of British Columbia, Canada
    Am J Clin Pathol 117:723-8. 2002
    ..The tissue microarray was an efficient and effective tool for identifying variability in ER reporting and should prove valuable in other external quality assurance programs...
  50. ncbi Morphologic spectrum of papillary carcinoma of the thyroid: role of cytology in identifying the variants
    Sanjay Gupta
    Division of Cytopathology, Institute of Cytology and Preventive Oncology, New Delhi, India
    Acta Cytol 48:795-800. 2004
    ..To evaluate the efficacy of fine needle aspiration cytology (FNAC) in the diagnosis of morphologic variants of papillary carcinoma of the thyroid (PCT) and to determine the reasons for misdiagnosis in discrepant cases on cytology...
  51. ncbi Testing in cervicovaginal cytology
    Leopold G Koss
    Arch Pathol Lab Med 130:13. 2006
  52. doi Nodal stage classification for breast carcinoma: improving interobserver reproducibility through standardized histologic criteria and image-based training
    Roderick R Turner
    Department of Pathology, Saint John s Health Center, 1328 Twenty Second St, Santa Monica, CA 90404, USA
    J Clin Oncol 26:258-63. 2008
    ..We sought to determine whether a set of clearly defined histologic criteria could lead to reproducible nodal classification by pathologists...
  53. ncbi Interpretive disparity among pathologists in breast sentinel lymph node evaluation
    Cory A Roberts
    Department of Pathology, St Paul University Hospital and University of Texas Southwestern Medical Center, Dallas, TX, USA
    Am J Surg 186:324-9. 2003
    ..Immunohistochemical staining on breast sentinel lymph nodes (SLN) is controversial...
  54. ncbi Misinterpretation of normal cellular elements in fine-needle aspiration biopsy specimens: observations from the College of American Pathologists Interlaboratory Comparison Program in Non-Gynecologic Cytopathology
    Nancy A Young
    Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Arch Pathol Lab Med 126:670-5. 2002
    ..Data generated from this program allow tracking pathologist performance in a wide variety of laboratory practices...
  55. ncbi Identification errors involving clinical laboratories: a College of American Pathologists Q-Probes study of patient and specimen identification errors at 120 institutions
    Paul N Valenstein
    Department of Pathology, St Joseph Mercy Hospital, Ann Arbor, Mich 48106 0998, USA
    Arch Pathol Lab Med 130:1106-13. 2006
    ..Misidentified laboratory specimens may cause patient injury, but their frequency in general laboratory practice is unknown...
  56. ncbi A new era for the Pap test
    E B Holladay
    Center for Quality Improvement in Gynecologic Cytopathology, Cytotechnology Program, Medical University of South Carolina, Charleston, USA
    JAAPA 14:53-6. 2001
    ..This relatively simple collection system will allow significant advances in molecular epidemiology and, in the future, development of a molecular Pap test...
  57. ncbi Image quality issues in a static image-based telepathology consultation practice
    Bruce H Williams
    Department of Telepathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
    Hum Pathol 34:1228-34. 2003
    ..A review of common image deficiencies in static-image telepathology and possible causes is presented...
  58. ncbi Altered recognition of reparative changes in ThinPrep specimens in the College of American Pathologists Gynecologic Cytology Program
    Tamela M Snyder
    Department of Pathology, The Methodist Hospital, Houston, Tex, USA
    Arch Pathol Lab Med 129:861-5. 2005
    ..It is unknown whether cytologists recognize reparative changes in ThinPrep specimens as well, or less often, as in conventional smears...
  59. ncbi A regional centralized microbiology service in Calgary for the rapid diagnosis of malaria
    Deirdre L Church
    Calgary Laboratory Services, Calgary, Alberta, Canada T3C 0J5
    Arch Pathol Lab Med 127:687-93. 2003
    ..A regional centralized laboratory service for the rapid diagnosis of malaria was implemented 3 years ago in May 1999 within the Division of Microbiology, Calgary Laboratory Services...
  60. ncbi Establishment of a central laboratory serum tumor marker service on a consolidated immunodiagnostic platform: development of practice standards, service improvements, and operational efficiency
    Patrick M Sluss
    Department of Pathology and Laboratory Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Clin Leadersh Manag Rev 18:25-31. 2004
    ..Over the past decade, serum tumor marker testing in patient management has become more defined, resulting in increasing test volume and wider availability of assays on automated immunodiagnostic platforms...
  61. pmc Clinical pathology accreditation: standards for the medical laboratory
    D Burnett
    Lindens Lodge, Bradford Place, Penarth CF64 1LA, UK
    J Clin Pathol 55:729-33. 2002
    This article describes a new set of revised standards for the medical laboratory, which have been produced by Clinical Pathology Accreditation (UK) Ltd (CPA)...
  62. ncbi Emerging concepts of quality assurance in clinical laboratories
    Sumera Naz
    Central Research Centre, Pakistan Medical Research Council, NIH, Islamabad
    J Pak Med Assoc 56:412-4. 2006
    ..Quality improvement in the modern clinical laboratory environment entails the continuous inspection and refinement of processes to ensure the efficient delivery of services that meet the needs and expectations of those who use them...
  63. doi Prostatic pathology reporting in the UK: development of a national external quality assurance scheme
    P Harnden
    Cancer Research UK Clinical Centre, St James s University Hospital, Leeds, UK
    Histopathology 52:147-57. 2008
    ....
  64. ncbi Longitudinal evaluation of interobserver and intraobserver agreement of cervical intraepithelial neoplasia diagnosis among an experienced panel of gynecologic pathologists
    Bing Cai
    Department of Epidemiology, Merck and Co, Inc, North Wales, PA 19454 1099, USA
    Am J Surg Pathol 31:1854-60. 2007
    ..These data indicate that the interpretation of histologic end points used in the quadrivalent vaccine clinical trial program is highly valid and reliable...
  65. ncbi [From the perspective of a clinical laboratory physician]
    Hiroshi Yoshida
    Department of Clinical Laboratory Medicine, Fukushima Medical University School of Medicine, Fukushima 960 1247
    Rinsho Byori 53:1155-8. 2005
    ..Laboratory physicians and technologists should pay more attention to laboratory tests being performed by examinees and outpatients themselves, and participate more in improving and evaluating the usefulness of these tests...
  66. ncbi Patient safety in the clinical laboratory: a longitudinal analysis of specimen identification errors
    Elizabeth A Wagar
    University of California, Los Angeles, Clinical Laboratories, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Box 951732, AL 206 CHS 10833 Le Conte Ave, Los Angeles, CA 90095 1732, USA
    Arch Pathol Lab Med 130:1662-8. 2006
    ....
  67. ncbi [From sample to report, a process analysis: presentation of two programmes for the improvement of professional practices, prepared by AFAQAP in partnership with HAS]
    Dominique Henin
    Service d Anatomie Pathologique, AP HP, CHU Bichat Claude Bernard, 46 rue Henri Huchard, 75877 Paris Cedex 18
    Ann Pathol 25:417-9. 2005
  68. ncbi A discussion of cases in the 2001 RCPA-AQAP Chemical Pathology Case Report Comments Program
    Ee Mun Lim
    Department of Biochemistry, Royal Perth Hospital, GPO Box X2213, PathCentre, Perth, WA 6847, Australia
    Pathology 35:145-50. 2003
    ....
  69. ncbi Critical values in anatomic pathology: how do we communicate?
    Virginia A LiVolsi
    Am J Clin Pathol 122:171-2. 2004
  70. ncbi The laboratory and patient safety
    Elizabeth A Wagar
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, 10833 Le Conte Road, Los Angeles, CA 90095, USA
    Clin Lab Med 27:909-30, viii-ix. 2007
    ..Emerging ideas on identifying and reducing laboratory errors, as well as specific strategies are reviewed and discussed with examples...
  71. ncbi National survey on critical values reporting in a cohort of Italian laboratories
    Giuseppe Lippi
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Clin Chem Lab Med 45:1411-3. 2007
    ..Critical values' reporting is an essential requisite for clinical laboratories. Local policies were investigated within an indicative cohort of Italian laboratories to monitor the situation and establish a performance benchmark...
  72. doi Accuracy of send-out test ordering: a College of American Pathologists Q-Probes study of ordering accuracy in 97 clinical laboratories
    Paul N Valenstein
    Department of Pathology, St Joseph Mercy Hospital, 5301 E Huron River Dr, Ann Arbor, MI 48106 0995, USA
    Arch Pathol Lab Med 132:206-10. 2008
    ..Errors entering orders for send-out laboratory tests into computer systems waste health care resources and can delay patient evaluation and management...
  73. ncbi Trends in blood culture contamination: a College of American Pathologists Q-Tracks study of 356 institutions
    Leonas G Bekeris
    Phoenixville Hospital Laboratory, Phoenixville, PA 19460, USA
    Arch Pathol Lab Med 129:1222-5. 2005
    ..Blood culture contamination extends hospital stays and increases the cost of care...
  74. ncbi Five-year follow-up of routine outpatient test turnaround time: a College of American Pathologists Q-Probes study
    Paul Valenstein
    Department of Pathology, St Joseph Mercy Hospital, Ann Arbor, Mich 48106 0995, USA
    Arch Pathol Lab Med 127:1421-3. 2003
    ..Timely reporting of outpatient tests can increase efficiency of care and improve customer satisfaction...
  75. ncbi Effects of carbon dioxide inhalation on hematology, coagulation, and serum clinical chemistry values in rats
    G L Walter
    MPI Research, Mattawan, Michigan, USA
    Toxicol Pathol 27:217-25. 1999
    ..These alterations reiterate the importance of comparing clinical pathology values to those of concurrent control groups that have experienced blood collection under identical ..
  76. ncbi Clinical pathology in the National Toxicology Program
    M B Thompson
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709
    Toxicol Pathol 20:484-8; discussion 488-9. 1992
    The National Toxicology Program (NTP) developed a standard approach for clinical pathology investigations that was integrated into most toxicity studies designed and conducted after 1986...
  77. ncbi Effects of sensitization to dinitrochlorobenzene (DNCB) on clinical pathology parameters and mitogen-mediated blastogenesis in cynomolgus monkeys (Macaca fascicularis)
    P J Bugelski
    Department of Experimental Pathology, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406 0939
    Toxicol Pathol 18:643-50. 1990
    ..The WBC parameters remained within the normal range and returned to pre-sensitization values at the later intervals.(ABSTRACT TRUNCATED AT 250 WORDS)..
  78. ncbi Clinical pathology: preanalytical variation in preclinical safety assessment studies--effect on predictive value of analyte tests
    J H Riley
    Department of Toxicology and Pathology, Hoffmann La Roche, Inc, Nutley, New Jersey 07110
    Toxicol Pathol 20:490-500. 1992
    ..Predictive value (likelihood of actual disease) of appropriate clinical pathology tests in toxicology is inversely dependent on preanalytical variation: uncontrolled variation produces data ..
  79. ncbi Changes in clinical pathology parameters during gestation in the New Zealand white rabbit
    M Y Wells
    L Oreal, Centre de Recherche Charles Zviak, Clichy, France
    Toxicol Pathol 27:370-9. 1999
    ..With a few exceptions, changes that occur in clinical pathology parameters during pregnancy in the rabbit are similar to those observed in pregnant women...
  80. ncbi Evaluation of the renal effects of an antisense phosphorothioate oligodeoxynucleotide in monkeys
    D K Monteith
    Isis Pharmaceuticals, Carlsbad, California 92008, USA
    Toxicol Pathol 27:307-17. 1999
    ..or an escalating dose regimen of 3, 10, 40, and 80 mg/kg of ISIS 2105 and were then evaluated for changes in clinical pathology indices, urinalysis parameters, and renal histopathology...
  81. ncbi Clinical pathology testing regulatory concerns
    J Kanno
    Department of Pathology, Faculty of Medicine, Tokyo Medical and Dental University, Japan
    Toxicol Pathol 20:534-7. 1992
    ..This situation will generate at least 2 practical problems in clinical pathology testing: (1) how to preselect test items without precise knowledge of toxicity endpoints and (2) how to ..
  82. ncbi Present status of animal clinical pathology examinations in the Japanese Pharmaceutical Manufacturers Association
    T Matsuzawa
    Safety Research Laboratories, Yamanouchi Pharmaceutical Co, Ltd, Tokyo, Japan
    Toxicol Pathol 20:528-33. 1992
    This paper will review the current status of animal clinical pathology in Japan using data obtained during a survey conducted by the Japanese Pharmaceutical Manufacturers Association (JPMA)...
  83. ncbi The measurement of renal injury
    W F Loeb
    Ani Lytics Inc, Gaithersburg, Maryland 20877, USA
    Toxicol Pathol 26:26-8. 1998
    ..Selection from a battery of clinical pathology tests allows the sensitive and specific measurement of renal dysfunction and injury...
  84. ncbi Recommendations for the reporting of extra-adrenal paragangliomas. The Association of Directors of Anatomic and Surgical Pathology
    Ernest E Lack
    Hum Pathol 34:112-3. 2003
  85. doi Learning in the working place: the educational potential of a multihead microscope in pathology postgraduate training
    Dominique Sandmeier
    Institut Universitaire de Pathologie, Centre Hospitalier Universitaire Vaudois CHUV, Universite de Lausanne, Lausanne, Switzerland
    Virchows Arch 454:257-61. 2009
    ..Finally, we propose clues for further studies and effective instruction during meetings around a multihead microscope...
  86. pmc The use of digital imaging, video conferencing, and telepathology in histopathology: a national survey
    T Dennis
    Department of Histopathology, Chesterfield and North Derbyshire Royal Hospital, Calow, Chesterfield S44 5BL, UK
    J Clin Pathol 58:254-8. 2005
    ..To undertake a large scale survey of histopathologists in the UK to determine the current infrastructure, training, and attitudes to digital pathology...
  87. ncbi CD-ROM transnational training program in cervical cytology (CYTOTRAIN)
    C Marsan
    collège de médecine des hôpitaux de Paris, and Department of Pathology and Cytopathology, Victor Dupouy Hospital Center, Argenteuil, France
    Diagn Cytopathol 24:71-5. 2001
    ....
  88. ncbi Clinical laboratory reports in molecular pathology
    Margaret L Gulley
    Department of Pathology, 913 Brinkhous Bullitt Bldg, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Arch Pathol Lab Med 131:852-63. 2007
    ..The recent introduction of array technology has added another layer of complexity involving massive parallel analysis of multiple genes, transcripts, or proteins...
  89. doi The advantage of using a synoptic pathology report format for cutaneous melanoma
    R Z Karim
    Department of Anatomical Pathology Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, Australia
    Histopathology 52:130-8. 2008
    ..The aim was to determine whether the use of synoptic reports increases the frequency with which pathological features that may influence prognosis and guide management are documented...
  90. ncbi Subaxial lesions in rheumatoid arthritis. Radiographic factors suggestive of lower cervical myelopathy
    T Yonezawa
    Department of Orthopaedic Surgery, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan
    Spine (Phila Pa 1976) 20:208-15. 1995
    ..SUMMARY OF BACKGROUND DATA. The clinical pathology and radiographic risk factor for upper cervical myelopathy in rheumatoid arthritis has been well documented, ..
  91. ncbi Recommendations for the reporting of prostate carcinoma
    Jonathan I Epstein
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Hum Pathol 38:1305-9. 2007
    ..However, ADASP hopes that pathologists will find these checklists useful in daily clinical practice while facilitating compliance with the new COC requirements...
  92. ncbi Laboratory automation: total and subtotal
    Charles D Hawker
    University of Utah School of Medicine, 30 N 1900 E Salt Lake City, UT 84132, USA
    Clin Lab Med 27:749-70, vi. 2007
    ..Finally, the role of standards in automation is reviewed...
  93. pmc Commissioning laboratory services
    R D Turner
    Directorate of Public Health, East Riding and Hull Health Authority, Grange Park Lane, Willerby, East Yorkshire HU10 6DT, UK
    Mol Pathol 54:225-6. 2001
    ..This article provides a practical guide...
  94. doi Assessment of critical values policies in Italian institutions: comparison with the US situation
    Elisa Piva
    Department of Laboratory Medicine, University Hospital of Padua, Padua, Italy
    Clin Chem Lab Med 48:461-8. 2010
    ..Here, we report the state of critical value reporting in a large cohort of Italian laboratories and comparison with Q-Probes surveys from the College of American Pathologists as representatives of the US situation...
  95. doi Veterinary Clinical Pathology: taking it to the next level
    Mary M Christopher
    Vet Clin Pathol 37:1-2. 2008
  96. ncbi Guidelines for the reporting of nongynecologic cytopathology specimens
    Barbara A Crothers
    Department of Pathology and Area Laboratory Services, Walter Reed Army Medical Center, Washington, District of Columbia 20307 5001, USA
    Arch Pathol Lab Med 133:1743-56. 2009
    ....
  97. ncbi A model for predicting pathologist's velocity profiles when navigating virtual slides
    Francisco Gomez
    Bioingenium Research Group, Ciudad Universitaria, National University of Colombia, Bogota DC, Colombia
    Microsc Res Tech 73:85-98. 2010
    ..The present approach is compared with other conventional prediction methods and decreases the calculated MSE in about a 50% for the entire group of pathologists...
  98. ncbi Improvement in the routine screening performance of cytotechnologists over time: a study using rapid prescreening
    Fadi Brimo
    Department of Pathology, McGill University Health Center and McGill University, Montreal, Quebec, Canada
    Cancer 117:311-7. 2009
    ..In the current study, the screening performance of 11 individual cytotechnologists as well as that of the overall laboratory over 2 consecutive time periods was examined using the rapid prescreening (RPS) method...
  99. ncbi Patient misidentification in Papanicolaou tests: a systems-based approach to reducing errors
    Erin Meyer
    Department of Pathology, Dartmouth Hitchcock Medical Center, One Medical Center Dr, Lebanon, NH 03756, USA
    Arch Pathol Lab Med 133:1297-300. 2009
    ..We use SurePath liquid-based cytology for Papanicolaou tests in our laboratory and noticed patient misidentification because of slide labeling errors, a problem that has not been addressed in the literature...
  100. doi Digital pathology in drug discovery and development: multisite integration
    Steven J Potts
    Aperio Technologies, Inc, Vista, CA 92081, United States
    Drug Discov Today 14:935-41. 2009
    ..This article reviews the stages of multisite digital pathology integration in large pharmaceutical companies, offering suggestions for success and highlighting challenges...
  101. doi What hematopathology tells us about the future of pathology informatics
    Jay L Hess
    Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109 5602, USA
    Arch Pathol Lab Med 133:908-11. 2009
    ..Hematopathology provides many insights into the challenges that pathology informatics will face in addressing the needs of a growing and aging population in the era of personalized medicine...

Research Grants104 found, 100 shown here

  1. TISSUE PROCUREMENT CORE FACILITY AT JOSEPHINE FORD CANCE
    RICHARD ZARBO; Fiscal Year: 2004
    ....
  2. Dermal-Epidermal Communication during Wound Healing
    Alan Wells; Fiscal Year: 2004
    ..The completion of these investigations will yield a model of dermal skin repair in which key extracellular and intracellular molecules are identified that can be targeted to either increase healing or limit scarring. ..
  3. INTEGRATION OF FIBROBLAST FUNCTIONING IN WOUND HEALING
    Alan Wells; Fiscal Year: 2001
    ..Understanding the delicate balance of these molecular mechanisms is important for rationally designing interventions to achieve normal wound healing. ..
  4. Dermal-Epidermal Communication during Wound Healing
    Alan Wells; Fiscal Year: 2006
    ..The completion of these investigations will yield a model of dermal skin repair in which key extracellular and intracellular molecules are identified that can be targeted to either increase healing or limit scarring. ..
  5. Spatial Segregation of Cell Functioning During Motility
    Alan Wells; Fiscal Year: 2006
    ..This will enable the design of'smart scaffolds for cell and tissue engineering directing the synthesis of both the matrix and the vascular bed that is reauired to sunnort tissue function. ..
  6. INTEGRATION OF FIBROBLAST FUNCTIONING IN WOUND HEALING
    Alan Wells; Fiscal Year: 2002
    ..Understanding the delicate balance of these molecular mechanisms is important for rationally designing interventions to achieve normal wound healing. ..
  7. Spatial Segregation of Cell Functioning During Motility
    Alan Wells; Fiscal Year: 2010
    ..These studies will define molecular bases for spatial restriction of receptor signaling and resultant biophysical responses, offering promise for design of 'smart'scaffolds for tissue engineering to support tissue function. ..
  8. Dermal-Epidermal Communication during Wound Healing
    Alan Wells; Fiscal Year: 2008
    ..These investigations will define key extracellular and intracellular molecules for wound resolution. These are potential targets for rationally designed interventions to promote normal wound healing and limit scarring. ..
  9. Dermal-Epidermal Communication during Wound Healing
    Alan Wells; Fiscal Year: 2003
    ..The completion of these investigations will yield a model of dermal skin repair in which key extracellular and intracellular molecules are identified that can be targeted to either increase healing or limit scarring. ..
  10. Dermal-Epidermal Communication during Wound Healing
    Alan Wells; Fiscal Year: 2005
    ..The completion of these investigations will yield a model of dermal skin repair in which key extracellular and intracellular molecules are identified that can be targeted to either increase healing or limit scarring. ..
  11. Spatial Segregation of Cell Functioning During Motility
    Alan Wells; Fiscal Year: 2005
    ..This will enable the design of'smart scaffolds for cell and tissue engineering directing the synthesis of both the matrix and the vascular bed that is reauired to sunnort tissue function. ..
  12. Dermal-Epidermal Communication during Wound Healing
    Alan Wells; Fiscal Year: 2009
    ..These investigations will define key extracellular and intracellular molecules that are potential targets for rationally designed interventions to promote normal wound healing and limit scarring. ..
  13. Spatial Segregation of Cell Functioning During Motility
    Alan Wells; Fiscal Year: 2009
    ..These studies will define molecular bases for spatial restriction of receptor signaling and resultant biophysical responses, offering promise for design of 'smart'scaffolds for tissue engineering to support tissue function. ..
  14. Spatial Segregation of Cell Functioning During Motility
    Alan Wells; Fiscal Year: 2004
    ..This will enable the design of'smart scaffolds for cell and tissue engineering directing the synthesis of both the matrix and the vascular bed that is reauired to sunnort tissue function. ..
  15. FIBROBLAST CELL MOTILITY IN WOUND HEALING
    Alan Wells; Fiscal Year: 1999
    ..That decreased wound healing in aging is, in part, due to decreased motility response of fibroblasts secondary to decreased signal transduction of the motility pathway. ..
  16. INTEGRATION OF FIBROBLAST FUNCTIONING IN WOUND HEALING
    Alan Wells; Fiscal Year: 2000
    ..Understanding the delicate balance of these molecular mechanisms is important for rationally designing interventions to achieve normal wound healing. ..
  17. Spatial Segregation of Cell Functioning During Motility
    Alan Wells; Fiscal Year: 2011
    ..These studies will define molecular bases for spatial restriction of receptor signaling and resultant biophysical responses, offering promise for design of 'smart'scaffolds for tissue engineering to support tissue function. ..
  18. Spatial Segregation of Cell Functioning During Motility
    Alan Wells; Fiscal Year: 2008
    ..These studies will define molecular bases for spatial restriction of receptor signaling and resultant biophysical responses, offering promise for design of 'smart' scaffolds for tissue engineering to support tissue function. ..
  19. Spatial Segregation of Cell Functioning During Motility
    Alan Wells; Fiscal Year: 2010
    ..abstract_text> ..
  20. Spatial Segregation of Cell Functioning During Motility
    Alan Wells; Fiscal Year: 2010
    ..abstract_text> ..
  21. Dermal-Epidermal Communication during Wound Healing
    Alan Wells; Fiscal Year: 2010
    ..These investigations will define key extracellular and intracellular molecules that are potential targets for rationally designed interventions to promote normal wound healing and limit scarring. ..
  22. Dermal-Epidermal Communication during Wound Healing
    Alan Wells; Fiscal Year: 2005
    ..The completion of these investigations will yield a model of dermal skin repair in which key extracellular and intracellular molecules are identified that can be targeted to either increase healing or limit scarring. ..
  23. Spatial Segregation of Cell Functioning During Motility
    Alan Wells; Fiscal Year: 2007
    ..This will enable the design of'smart scaffolds for cell and tissue engineering directing the synthesis of both the matrix and the vascular bed that is reauired to sunnort tissue function. ..
  24. INTEGRATION OF FIBROBLAST FUNCTIONING IN WOUND HEALING
    Alan Wells; Fiscal Year: 2003
    ..Understanding the delicate balance of these molecular mechanisms is important for rationally designing interventions to achieve normal wound healing. ..
  25. Interferon gamma in autoimmune thyroiditis & thyroid function
    Patrizio Caturegli; Fiscal Year: 2007
    ..We also hypothesize that augmented TSH signaling is required to induce the adipocyte-rich phenotype, and cross thyr-IFNg transgenics to TSH receptor knockout mice. ..
  26. BRAINSTEM MATURATION IN THE SUDDEN INFANT DEATH SYNDROME
    Hannah Kinney; Fiscal Year: 2007
    ..abstract_text> ..
  27. Prostate Cancer Harbinger Genes
    Mark Rubin; Fiscal Year: 2004
    ..abstract_text> ..
  28. Alpha2Beta1 Integrin and Cell Surface MMP-1 Activity
    Samuel Santoro; Fiscal Year: 2004
    ..abstract_text> ..
  29. IMMUNOHEMATOLOGY/TRANSFUSION MEDICINE RESEARCH TRAINING
    Brian Smith; Fiscal Year: 2007
    ..We see this program as filling an important research training need both at Yale and nationally. (End of Abstract) ..
  30. Improving Patient Safety by Examining Pathology Errors
    Stephen Raab; Fiscal Year: 2004
    ..abstract_text> ..
  31. MOUSE PATHOBIOLOGY: MODELS OF HUMAN DISEASE
    Michael Lairmore; Fiscal Year: 2008
    ....
  32. Prostate Cancer Harbinger Genes
    Mark Rubin; Fiscal Year: 2006
    ..abstract_text> ..
  33. Therapeutics to Prevent/Treat Lassa Fever Virus
    Michael Oldstone; Fiscal Year: 2006
    ..abstract_text> ..
  34. Arenavirus Receptor-Structure/Function Studies
    Michael Oldstone; Fiscal Year: 2006
    ..These findings have relevance for biodefense of several viruses including LFV. ..
  35. Advances in the pathogenesis of non-thyroidal illness
    Patrizio Caturegli; Fiscal Year: 2008
    ..Its pathogenesis is poorly understood. In this application we propose a new mechanism for NTI based on the interaction between mast cells and leptin. ..
  36. Gene Amplification and Deletion in Pancreatic Cancer
    Jonathan Pollack; Fiscal Year: 2008
    ..abstract_text> ..
  37. Prostate Cancer Harbinger Genes
    Mark Rubin; Fiscal Year: 2005
    ..abstract_text> ..
  38. Functions of ERK and p38 MAP Kinases in Astrogliosis
    James Mandell; Fiscal Year: 2008
    ..This approach could promote recovery of brain and spinal cord function after injury or stroke. [unreadable] [unreadable]..
  39. "Molecular Signatures of Lethal and Indolent Prostate Cancer"
    Mark Rubin; Fiscal Year: 2006
    ..At the conclusion of this proposal, we expect to have refined and fully validated molecular predictors of PCA death as well as indolent PCA that is appropriate for further clinical development. [unreadable] [unreadable] [unreadable]..
  40. The TCGA Cancer Genome Characterization Center at MSKCC
    Marc Ladanyi; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  41. Platelet-Leukocyte Physiology in Cardiopulmonary Bypass
    Brian Smith; Fiscal Year: 2004
    ..induced by SECC; (3) examine the effects of SECC on human endothelial cells by in vitro modeling, specifically including alterations in tissue factor regulation and the effect of differential complement components ..
  42. Arenavirus Receptor-Structure/Function Studies
    Michael B Oldstone; Fiscal Year: 2010
    ..These findings have relevance for biodefense of several viruses including LFV. ..
  43. Pathogenetics of a Clinically-favorable Prostate Cancer Subtype
    Jonathan R Pollack; Fiscal Year: 2010
    ..Our findings may also suggest novel gene-based markers for the diagnosis of clinically- favorable tumors, leading to improved treatment stratification and clinical management of men with prostate cancer. ..
  44. PLATELET LEUKOCYTE PHYSIOLOGY IN CARDIOPULMONARY BYPASS
    Brian Smith; Fiscal Year: 2001
    ..The long term goals of these studies is to develop therapeutic strategies to alleviate complications of extracorporeal circulation and to understand the basic biology of platelet-white blood cell-erthyrocyte-endothelial interactions. ..
  45. Gene Amplification and Deletion in Pancreatic Cancer
    Jonathan R Pollack; Fiscal Year: 2010
    ..abstract_text> ..
  46. VIRUSES AND AUTOIMMUNE DISEASE
    Michael Oldstone; Fiscal Year: 2000
    ..The second order of business is to determine the role of "self" (islet-cell) antigens other than the initial triggering viral antigen in the pathogenetic process leading to and determine their role in IDDM. ..
  47. REVERSIBLE PATHOLOGY OF THE PLATELET STORAGE LESION
    Brian Smith; Fiscal Year: 1999
    ..The long term goal of the project, which combines the synergistic expertise of several established investigators, is to improve the clinical results of platelet transfusion. ..
  48. PLATELET-LEUKOCYTE PATHOBIOLOGY IN CARDIOPULMONARY BYPAS
    Brian Smith; Fiscal Year: 1993
    ....
  49. ANIMAL MODELS OF MOLECULAR PATHOGENSIS OF HTLV-1
    Michael Lairmore; Fiscal Year: 2001
    ..Collectively, our research groups provide a coordinated approach to develop state-of-the-art animal models to further knowledge of the events of HTLV-1 pathogenesis. ..
  50. MEASLES VIRUS STUDIES IN A TRANSGENIC MODEL
    Michael Oldstone; Fiscal Year: 2003
    ..abstract_text> ..
  51. Hypoglycemic signaling targets in astrocytes
    James Mandell; Fiscal Year: 2003
    ..The longterm goal is to develop pharmacologic or molecular methods to augment or modulate neuroprotective aspects of the astrocytic response to hypoglycemia. ..
  52. ARENAVIRUS RECEPTOR--STRUCTURE/FUNCTION STUDIES
    Michael Oldstone; Fiscal Year: 2003
    ..We will also analyze alpha-DG content on IDDC and F4/80+ cells and look for coreceptor(s). ..
  53. VIRTUAL SLIDEBOX OF COMPARATIVE CANCER PATHOLOGY
    Fred Dee; Fiscal Year: 2003
    ..abstract_text> ..
  54. Molecular Characterization of Leiomyosarcoma and GIST
    JAN VAN DE RIJN; Fiscal Year: 2009
    ..abstract_text> ..
  55. Pathogenetics of a Clinically-favorable Prostate Cancer Subtype
    Jonathan Pollack; Fiscal Year: 2009
    ..Our findings will further our understanding of the pathogenesis of prostate cancer, and may suggest novel gene-based markers for an improved classification of prostate tumors and management of patients with prostate cancer. ..
  56. ROLE OF INTERFERON GAMMA IN THYROIDITIS
    Patrizio Caturegli; Fiscal Year: 2003
    ..Furthermore, the understanding of the pathogenesis can open new avenues for diagnosis, prognosis, and treatment of these and other organ-specific autoimmune diseases. ..
  57. Clinical Trials in Transfusion Medicine and Hemostasis
    Jeffrey McCullough; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable] UNIVERSITY OF MINNESOTA CRITIQUES [unreadable] [unreadable] [unreadable] [unreadable]..
  58. Clinical Trials in Transfusion Medicine and Hemostasis
    Jeffrey McCullough; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable] UNIVERSITY OF MINNESOTA CRITIQUES [unreadable] [unreadable] [unreadable] [unreadable]..
  59. Retrovirus Models of Lymphocyte Transformation and Disease
    Michael Lairmore; Fiscal Year: 2008
    ....
  60. Predictive Biomarkers of Adjuvant Trastuzumab in the HER2+N9831 Intergroup Trial
    MONICA MADDEN REINHOLZ; Fiscal Year: 2010
    ..Our study proposes biomarker tissue correlative studies to help identify those patients most likely to benefit from this treatment. ..
  61. Retrovirus Models of Lymphocyte Transformation/Disease
    Michael Lairmore; Fiscal Year: 2007
    ....
  62. Competencies Training &Assessment in LaboratoryMedicine UsingPatientSimulations
    Fred Dee; Fiscal Year: 2008
    ..research will be carried out in medical school courses at the University of Iowa an in laboratory medicine (clinical pathology) residency training programs at the University of Iowa Hospitals and Clinics and elsewhere...
  63. "Molecular Signatures of Lethal and Indolent Prostate Cancer"
    Mark Rubin; Fiscal Year: 2008
    ..At the conclusion of this proposal, we expect to have refined and fully validated molecular predictors of PCA death as well as indolent PCA that is appropriate for further clinical development. ..
  64. PATHOGENESIS OF PERSISTENT VIRAL INFECTION
    Michael Oldstone; Fiscal Year: 2008
    ....
  65. Novel Chemical and Immunological Approaches to Influenza Therapy
    Michael Oldstone; Fiscal Year: 2008
    ..Kawaoka will test novel sphingosine analogs against H5N1 influenza virus. ..
  66. Predictive Biomarkers of Adjuvant Trastuzumab in the HER2+N9831 Intergroup Trial
    Edith Perez; Fiscal Year: 2009
    ..Our study proposes biomarker tissue correlative studies to help identify those patients most likely to benefit from this treatment. ..
  67. Gene Amplification and Deletion in Pancreatic Cancer
    Jonathan Pollack; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  68. Therapeutics to Prevent/Treat Lassa Fever Virus
    Michael Oldstone; Fiscal Year: 2004
    ..abstract_text> ..
  69. Pathogenesis Studies in Scrapie (TSE Diseases)
    Michael Oldstone; Fiscal Year: 2003
    ..This model should be useful to study pathophysiology of CWD as well as probing CWD strain differences. ..
  70. Prostate Cancer Harbinger Genes
    Mark Rubin; Fiscal Year: 2003
    ..abstract_text> ..
  71. Mechanism of p12I and p30II in HTLV1 Infection
    Michael Lairmore; Fiscal Year: 2003
    ..Our long-term goal is to understand the role of p12-I and p30-II in the establishment of HTLV-1 infection in vivo. ..
  72. VASCULAR CELL COLLAGEN RECEPTORS
    Samuel Santoro; Fiscal Year: 2001
    ..abstract_text> ..
  73. ANIMAL MODELS OF MOLECULAR PATHOGENSIS OF HTLV-1
    Michael Lairmore; Fiscal Year: 2000
    ..Collectively, our research groups provide a coordinated approach to develop state-of-the-art animal models to further knowledge of the events of HTLV-1 pathogenesis. ..
  74. PATHOGENESIS OF PERSISTENT VIRAL INFECTION
    Michael Oldstone; Fiscal Year: 2000
    ..The eventual goal is to understand and then manipulate, for the profit of the host, the early events of arenavirus entry into cells. ..
  75. MEASLES VIRUS STUDIES IN A TRANSGENIC MODEL
    Michael Oldstone; Fiscal Year: 2000
    ..The other newly made tg mice express CD46 widely (genomic CD46, CD46 driven by CMV promoter). The P.I. anticipates that these mice will be of value for similar studies. ..
  76. MEASLES VIRUS STUDIES IN A TRANSGENIC MODEL
    Michael Oldstone; Fiscal Year: 1999
    ..The other newly made tg mice express CD46 widely (genomic CD46, CD46 driven by CMV promoter). The P.I. anticipates that these mice will be of value for similar studies. ..
  77. VIRTUAL SLIDEBOX OF COMPARATIVE CANCER PATHOLOGY
    Fred Dee; Fiscal Year: 2005
    ..abstract_text> ..
  78. RESEARCH TRAINING FOR VETERINARY STUDENTS
    Michael Lairmore; Fiscal Year: 2005
    ....
  79. Role of Gene Amplification in Breast Cancer
    Jonathan Pollack; Fiscal Year: 2006
    ..abstract_text> ..
  80. ARENAVIRUS RECEPTOR--STRUCTURE/FUNCTION STUDIES
    Michael Oldstone; Fiscal Year: 2007
    ..These findings have relevance for biodefense of several viruses including LFV. ..
  81. Gene Amplification and Deletion in Pancreatic Cancer
    Jonathan Pollack; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  82. PATHOGENESIS OF PERSISTENT VIRAL INFECTION
    Michael Oldstone; Fiscal Year: 2006
    ..Lessons learned from this aspect of the LCMV model should provide insights for several persistent human viral infections that cause immunosuppression. ..
  83. Competencies Training &Assessment in LaboratoryMedicine UsingPatientSimulations
    Fred Dee; Fiscal Year: 2007
    ..research will be carried out in medical school courses at the University of Iowa an in laboratory medicine (clinical pathology) residency training programs at the University of Iowa Hospitals and Clinics and elsewhere...
  84. PLATELET LEUKOCYTE PHYSIOLOGY IN CARDIOPULMONARY BYPASS
    Brian Smith; Fiscal Year: 2000
    ..The long term goals of these studies is to develop therapeutic strategies to alleviate complications of extracorporeal circulation and to understand the basic biology of platelet-white blood cell-erthyrocyte-endothelial interactions. ..
  85. STUDIES OF A NEW MYELIN GENE THAT CAUSES CNS DISEASE
    Michael Oldstone; Fiscal Year: 2001
    ..Their studies in rodents combined with those of their collaborator, Dr. Martin, should begin to characterize the role played by MONP in neurologic disease. ..
  86. PATHOGENESIS OF PERSISTENT VIRAL INFECTION
    Michael Oldstone; Fiscal Year: 1999
    ..The eventual goal is to understand and then manipulate, for the profit of the host, the early events of arenavirus entry into cells. ..
  87. RESEARCH TRAINING FOR VETERINARY STUDENTS
    Michael Lairmore; Fiscal Year: 2003
    ....
  88. Platelet-Leukocyte Physiology in Cardiopulmonary Bypass
    Brian Smith; Fiscal Year: 2003
    ..induced by SECC; (3) examine the effects of SECC on human endothelial cells by in vitro modeling, specifically including alterations in tissue factor regulation and the effect of differential complement components ..
  89. MOUSE PATHOBIOLOGY: MODELS OF HUMAN DISEASE
    Michael Lairmore; Fiscal Year: 2007
    ....
  90. Alpha2Beta1 Integrin and Cell Surface MMP-1 Activity
    Samuel Santoro; Fiscal Year: 2005
    ..abstract_text> ..
  91. Novel Chemical and Immunological Approaches to Influenza Therapy
    Michael Oldstone; Fiscal Year: 2007
    ..Kawaoka will test novel sphingosine analogs against H5N1 influenza virus. ..
  92. PATHOGENESIS OF PERSISTENT VIRAL INFECTION
    Michael Oldstone; Fiscal Year: 2007
    ..Lessons learned from this aspect of the LCMV model should provide in_,iohts for several persistent human viral infections that _ause immunosuooression. ..
  93. EMPLOYMENT DYNAMICS IN RESPONSE TO WELFARE REFORM
    Isaac Montoya; Fiscal Year: 2002
    ..Analyses will yield an Employment Readiness Profile that summarizes the changes over time within and between the samples of drug users and non-drug users and the independent effect of drug use on achieving employment. ..