gene order

Summary

Summary: The sequential location of genes on a chromosome.

Top Publications

  1. pmc The architecture and complete sequence of mitochondrial genome of an assassin bug Agriosphodrus dohrni (Hemiptera: Reduviidae)
    Hu Li
    Department of Entomology, China Agricultural University, Beijing 100193, China
    Int J Biol Sci 7:792-804. 2011
  2. pmc The complete mitochondrial genome and novel gene arrangement of the unique-headed bug Stenopirates sp. (Hemiptera: Enicocephalidae)
    Hu Li
    Department of Entomology, China Agricultural University, Beijing, China
    PLoS ONE 7:e29419. 2012
  3. pmc Gene order and chromosome dynamics coordinate spatiotemporal gene expression during the bacterial growth cycle
    Patrick Sobetzko
    School of Engineering and Science, Jacobs University Bremen, D 28759 Bremen, Germany
    Proc Natl Acad Sci U S A 109:E42-50. 2012
  4. pmc Unraveling ancient hexaploidy through multiply-aligned angiosperm gene maps
    Haibao Tang
    Plant Genome Mapping Laboratory, University of Georgia, Athens, Georgia 30602, USA
    Genome Res 18:1944-54. 2008
  5. ncbi Comparison of the genomes of two Xanthomonas pathogens with differing host specificities
    A C R da Silva
    Departamento de Bioquimica, Instituto de Quimica, Av Prof Lineu Prestes 748, Sao Paulo, SP, Brazil
    Nature 417:459-63. 2002
  6. ncbi Unravelling angiosperm genome evolution by phylogenetic analysis of chromosomal duplication events
    John E Bowers
    Plant Genome Mapping Laboratory, University of Georgia, Athens, Georgia 30602, USA
    Nature 422:433-8. 2003
  7. pmc Support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation
    Claudia C Weber
    Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK
    Genome Biol 12:R23. 2011
  8. pmc The complete mitochondrial genome of the bag-shelter moth Ochrogaster lunifer (Lepidoptera, Notodontidae)
    Paola Salvato
    Department of Public Health, Comparative Pathology and Veterinary Hygiene, University of Padova, Agripolis, Viale dell Universita 16, 35020 Legnaro, Italy
    BMC Genomics 9:331. 2008
  9. ncbi A nonribosomal peptide synthetase gene (mgoA) of Pseudomonas syringae pv. syringae is involved in mangotoxin biosynthesis and is required for full virulence
    Eva Arrebola
    Departamento de Microbiologia, Facultad de Ciencias, Universidad de Malaga, Malaga, Spain
    Mol Plant Microbe Interact 20:500-9. 2007
  10. pmc A fragmented metazoan organellar genome: the two mitochondrial chromosomes of Hydra magnipapillata
    Oliver Voigt
    Courant Research Center Geobiology, Georg August Universitat Gottingen, Goldschmidtstr, 3, 37077 Gottingen, Germany
    BMC Genomics 9:350. 2008

Research Grants

Detail Information

Publications254 found, 100 shown here

  1. pmc The architecture and complete sequence of mitochondrial genome of an assassin bug Agriosphodrus dohrni (Hemiptera: Reduviidae)
    Hu Li
    Department of Entomology, China Agricultural University, Beijing 100193, China
    Int J Biol Sci 7:792-804. 2011
    ..dimidiata and Valentia hoffmanni, exhibited highly conserved genome architectures including genome contents, gene order, nucleotide composition, codon usage, amino acid composition, as well as genome asymmetry...
  2. pmc The complete mitochondrial genome and novel gene arrangement of the unique-headed bug Stenopirates sp. (Hemiptera: Enicocephalidae)
    Hu Li
    Department of Entomology, China Agricultural University, Beijing, China
    PLoS ONE 7:e29419. 2012
    ..The gene order differs substantially from other known insect mitochondrial genomes, with rearrangements of both tRNA genes and ..
  3. pmc Gene order and chromosome dynamics coordinate spatiotemporal gene expression during the bacterial growth cycle
    Patrick Sobetzko
    School of Engineering and Science, Jacobs University Bremen, D 28759 Bremen, Germany
    Proc Natl Acad Sci U S A 109:E42-50. 2012
    ....
  4. pmc Unraveling ancient hexaploidy through multiply-aligned angiosperm gene maps
    Haibao Tang
    Plant Genome Mapping Laboratory, University of Georgia, Athens, Georgia 30602, USA
    Genome Res 18:1944-54. 2008
    ..Comparative analysis of inferred homologous genes derived from this model shows patterns of preferential gene retention or loss after polyploidy and reveals large variability of nucleotide substitution rates among plant nuclear genomes...
  5. ncbi Comparison of the genomes of two Xanthomonas pathogens with differing host specificities
    A C R da Silva
    Departamento de Bioquimica, Instituto de Quimica, Av Prof Lineu Prestes 748, Sao Paulo, SP, Brazil
    Nature 417:459-63. 2002
    ..More than 80% of genes are shared, and gene order is conserved along most of their respective chromosomes...
  6. ncbi Unravelling angiosperm genome evolution by phylogenetic analysis of chromosomal duplication events
    John E Bowers
    Plant Genome Mapping Laboratory, University of Georgia, Athens, Georgia 30602, USA
    Nature 422:433-8. 2003
    Conservation of gene order in vertebrates is evident after hundreds of millions of years of divergence, but comparisons of the Arabidopsis thaliana sequence to partial gene orders of other angiosperms (flowering plants) sharing common ..
  7. pmc Support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation
    Claudia C Weber
    Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK
    Genome Biol 12:R23. 2011
    b>Gene order in eukaryotic genomes is not random, with genes with similar expression profiles tending to cluster...
  8. pmc The complete mitochondrial genome of the bag-shelter moth Ochrogaster lunifer (Lepidoptera, Notodontidae)
    Paola Salvato
    Department of Public Health, Comparative Pathology and Veterinary Hygiene, University of Padova, Agripolis, Viale dell Universita 16, 35020 Legnaro, Italy
    BMC Genomics 9:331. 2008
    ..Thus advance of lepidopteran mitogenomics deeply requires new genomes derived from a broad taxon sampling. In present work we describe the mitochondrial genome of the moth Ochrogaster lunifer...
  9. ncbi A nonribosomal peptide synthetase gene (mgoA) of Pseudomonas syringae pv. syringae is involved in mangotoxin biosynthesis and is required for full virulence
    Eva Arrebola
    Departamento de Microbiologia, Facultad de Ciencias, Universidad de Malaga, Malaga, Spain
    Mol Plant Microbe Interact 20:500-9. 2007
    ..syringae pv. syringae. The involvement of an NRPS in the production of an antimetabolite toxin from P. syringae inhibiting ornithine acetyltransferase activity is proposed...
  10. pmc A fragmented metazoan organellar genome: the two mitochondrial chromosomes of Hydra magnipapillata
    Oliver Voigt
    Courant Research Center Geobiology, Georg August Universitat Gottingen, Goldschmidtstr, 3, 37077 Gottingen, Germany
    BMC Genomics 9:350. 2008
    ..Here, we present the whole mt genome sequence from the hydrozoan Hydra magnipapillata, comprising the first sequence of a fragmented metazoan mt genome encoded on two linear mt chromosomes (mt1 and mt2)...
  11. ncbi Complete mtDNA sequences of two millipedes suggest a new model for mitochondrial gene rearrangements: duplication and nonrandom loss
    Dennis V Lavrov
    Department of Biology, University of Michigan, Ann Arbor, USA
    Mol Biol Evol 19:163-9. 2002
    ..The proposed mechanism has important implications for phylogenetic inferences that are drawn on the basis of gene arrangement comparisons...
  12. pmc Genome sequences of three agrobacterium biovars help elucidate the evolution of multichromosome genomes in bacteria
    Steven C Slater
    Virginia Bioinformatics Institute, Washington St, MC 0477, Blacksburg, VA 24060, USA
    J Bacteriol 191:2501-11. 2009
    ..In contrast, secondary chromosomes share smaller percentages of genes, and conserved gene order is restricted to short blocks...
  13. doi Two circular chromosomes of unequal copy number make up the mitochondrial genome of the rotifer Brachionus plicatilis
    Koushirou Suga
    Nagasaki Industrial Promotion Foundation, Omura, Japan
    Mol Biol Evol 25:1129-37. 2008
    ..b>Gene order is not conserved between B...
  14. pmc Sessile snails, dynamic genomes: gene rearrangements within the mitochondrial genome of a family of caenogastropod molluscs
    Timothy A Rawlings
    Cape Breton University, 1250 Grand Lake Road, Sydney, NS B1P 6L2, Canada
    BMC Genomics 11:440. 2010
    ..In contrast, more limited sampling within the Phylum Mollusca has revealed an unusually high number of gene order arrangements...
  15. doi The mitochondrial genome of the butterfly Papilio xuthus (Lepidoptera: Papilionidae) and related phylogenetic analyses
    Xia Feng
    Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, No 1, Wenyuan Road, 210046, Nanjing, Jiangsu, People s Republic of China
    Mol Biol Rep 37:3877-88. 2010
    ..The genome has a typical gene order identical to other lepidopteran species...
  16. doi The complete mitochondrial genome of the yellow coaster, Acraea issoria (Lepidoptera: Nymphalidae: Heliconiinae: Acraeini): sequence, gene organization and a unique tRNA translocation event
    Jing Hu
    College of Life Sciences, Anhui Normal University, Wuhu, 241000, China
    Mol Biol Rep 37:3431-8. 2010
    ..There are some short microsatellite-like repeat regions (e.g., (TA)(9), polyA and polyT) scattered in the control region, however, the conspicuous macro-repeats units commonly found in other insect species are absent...
  17. pmc Comparative and phylogenomic studies on the mitochondrial genomes of Pentatomomorpha (Insecta: Hemiptera: Heteroptera)
    Jimeng Hua
    Department of Zoology and Developmental Biology, Institute of Entomology, College of Life Sciences, Nankai University, Tianjin 300071, PR China
    BMC Genomics 9:610. 2008
    ....
  18. doi Complete mitochondrial genomes of two Japanese precious corals, Paracorallium japonicum and Corallium konojoi (Cnidaria, Octocorallia, Coralliidae): notable differences in gene arrangement
    Kouji Uda
    Laboratories of Biochemistry, Faculty of Science, Kochi University, Kochi 780 8520, Japan
    Gene 476:27-37. 2011
    ..sequences belonging to species in the subclass Octocorallia indicated that within the subclass, at least three gene order rearrangement events occurred during evolution...
  19. doi Extensive rearrangements in the chloroplast genome of Trachelium caeruleum are associated with repeats and tRNA genes
    Rosemarie C Haberle
    Section of Integrative Biology and Institute of Cellular and Molecular Biology, University of Texas, Austin, TX 78712, USA
    J Mol Evol 66:350-61. 2008
    Chloroplast genome organization, gene order, and content are highly conserved among land plants. We sequenced the chloroplast genome of Trachelium caeruleum L...
  20. pmc The complete mitochondrial genome of the Asiatic cavity-nesting honeybee Apis cerana (Hymenoptera: Apidae)
    Hong Wei Tan
    State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, China
    PLoS ONE 6:e23008. 2011
    ..The complete mtDNA sequence of A. cerana provides additional genetic markers for studying population genetics, systematics and phylogeographics of honeybees...
  21. doi Inference of the phylogenetic position of the phylum Deferribacteres from gene order comparison
    Takashi Kunisawa
    Department of Applied Biological Sciences, Science University of Tokyo, Noda, Japan
    Antonie Van Leeuwenhoek 99:417-22. 2011
    The phylogenetic placement of the phylum Deferribacteres was investigated on the basis of gene order comparisons of completely sequenced bacterial genomes...
  22. pmc Genome and proteome analysis of 7-7-1, a flagellotropic phage infecting Agrobacterium sp H13-3
    Andrew M Kropinski
    Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, Guelph, ON, NIG 3W4, Canada
    Virol J 9:102. 2012
    ..Here we describe the complete genomic sequence of 69,391 base pairs of this unusual bacteriophage...
  23. doi Chromatin structure and the regulation of gene expression: the lessons of PEV in Drosophila
    Jack R Girton
    Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA
    Adv Genet 61:1-43. 2008
    ..Current studies of PEV are focusing on defining the complex patterns of modifier gene activity and the sequence of events that leads to the dynamic interplay between heterochromatin and euchromatin...
  24. pmc The mitochondrial genome of the lycophyte Huperzia squarrosa: the most archaic form in vascular plants
    Yang Liu
    Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 7:e35168. 2012
    ..It also has the least rearranged gene order in comparison to the chondromes of other vascular plants...
  25. pmc Comparative genomics of multidrug resistance-encoding IncA/C plasmids from commensal and pathogenic Escherichia coli from multiple animal sources
    Claudia Fernandez-Alarcon
    Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota, United States of America
    PLoS ONE 6:e23415. 2011
    ....
  26. doi eGOB: eukaryotic Gene Order Browser
    Marcela Dávila López
    Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, SE 405 30 Goteborg, Sweden
    Bioinformatics 27:1150-1. 2011
    ..Here, we present the eukaryotic Gene Order Browser with information on the order of protein and non-coding RNA (ncRNA) genes of 74 different eukaryotic ..
  27. doi Complete mitochondrial genome sequences of the three pelagic chaetognaths Sagitta nagae, Sagitta decipiens and Sagitta enflata
    Hiroomi Miyamoto
    Ocean Research Institute, University of Tokyo, Tokyo, 164 8639, Japan
    Comp Biochem Physiol Part D Genomics Proteomics 5:65-72. 2010
    ..The gene order of this cluster was also assumed to be the ancestral state of the phylum.
  28. doi Comparative genomics and phylogeny of the IncI1 plasmids: a common plasmid type among porcine enterotoxigenic Escherichia coli
    Timothy J Johnson
    Department of Veterinary and Biomedical Sciences, University of Minnesota, 1971 Commonwealth Avenue, 205 Veterinary Science, St Paul, MN 55108, USA
    Plasmid 66:144-51. 2011
    ..Furthermore, the high occurrence of IncI1 and IncA/C plasmids among clinical E. coli from commercial swine facilities is indicative of extensive horizontal gene transfer among porcine ETEC...
  29. doi The complete mitochondrial genome of Symphylella sp. (Myriapoda: Symphyla): Extensive gene order rearrangement and evidence in favor of Progoneata
    Yonghua Gai
    Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210046, China Nanjing Institute of Geology and Palaeontology, Chinese Academy of Science, Nanjing 210008, China
    Mol Phylogenet Evol 49:574-85. 2008
    ..With respect to the ancestral arthropod mitochondrial gene order, two protein-coding genes, the rRNAs and 10 of the tRNAs appear to be rearranged...
  30. pmc Complete DNA sequences of the plastid genomes of two parasitic flowering plant species, Cuscuta reflexa and Cuscuta gronovii
    Helena T Funk
    Department of Cell Biology, Philipps University Marburg, Karl von Frisch Str, D 35032 Marburg, Germany
    BMC Plant Biol 7:45. 2007
    ..reflexa to a restricted photosynthetic activity and degenerated chloroplasts in C. gronovii to an achlorophyllous state in E. virginiana...
  31. pmc Identification of mammalian orthologs using local synteny
    Jin Jun
    Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269, USA
    BMC Genomics 10:630. 2009
    ..have been most successfully implemented in fungal genomes and have long been used in prokaryotic genomes, where gene order is far less variable than in vertebrates...
  32. pmc Complete DNA sequences of the mitochondrial genomes of the pathogenic yeasts Candida orthopsilosis and Candida metapsilosis: insight into the evolution of linear DNA genomes from mitochondrial telomere mutants
    Peter Kosa
    Department of Biochemistry, Faculty of Natural Sciences, Comenius University Mlynska dolina, CH 1 and B 1, 842 15, Bratislava, Slovak Republic
    Nucleic Acids Res 34:2472-81. 2006
    ....
  33. doi Complete mitochondrial genome of the small brown planthopper, Laodelphax striatellus (Delphacidae: Hemiptera), with a novel gene order
    Nan Song
    Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing 100101, China
    Zoolog Sci 26:851-60. 2009
    ..striatellus mitogenome is identical to other completely sequenced insect mitogenomes, while the gene order is different from the common arrangement found in most insects: five tRNA genes and three PCGs in the L...
  34. doi Complete mitochondrial genome of brown marmorated stink bug Halyomorpha halys (Hemiptera: Pentatomidae), and phylogenetic relationships of hemipteran suborders
    Wonhoon Lee
    Insect Biosystematics Laboratory, Research Institute for Agricultural and Life Sciences, Department of Agricultural Biotechnology, Seoul National University, Korea
    Mol Cells 28:155-65. 2009
    ..The mitochondrial gene arrangements of the 20 genomes=are also consistent with our results...
  35. doi Transcriptional coupling of neighboring genes and gene expression noise: evidence that gene orientation and noncoding transcripts are modulators of noise
    Guang Zhong Wang
    Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, United Kingdom
    Genome Biol Evol 3:320-31. 2011
    ..We conclude that gene orientation and transcription of ncRNAs are candidate modulators of noise...
  36. pmc High-density linkage mapping and evolution of paralogs and orthologs in Salix and Populus
    Sofia Berlin
    Department of Plant Biology and Forest Genetics, Uppsala BioCenter, Swedish University of Agricultural Sciences, PO Box 7090, SE 750 07 Uppsala, Sweden
    BMC Genomics 11:129. 2010
    ..The marker positions in the two genomes were used to study genome evolution since the divergence of the two lineages some 45 mya...
  37. pmc Discovery of stable and variable differences in the Mycobacterium avium subsp. paratuberculosis type I, II, and III genomes by pan-genome microarray analysis
    Elena Castellanos
    Centro de Vigilancia Sanitaria Veterinaria, Departamento Sanidad Animal, Universidad Complutense, Madrid, Spain
    Appl Environ Microbiol 75:676-86. 2009
    ..Quantitative PCR demonstrated that variation in vGI signals could be associated with colony growth rate and morphology...
  38. pmc Identification and characterization of catabolic para-nitrophenol 4-monooxygenase and para-benzoquinone reductase from Pseudomonas sp. strain WBC-3
    Jun Jie Zhang
    Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China
    J Bacteriol 191:2703-10. 2009
    ..J. Moonen, N. M. Kamerbeek, A. H. Westphal, S. A. Boeren, D. B. Janssen, M. W. Fraaije, and W. J. van Berkel, J. Bacteriol. 190:5190-5198, 2008), suggesting that the genes involved in PNP degradation are physically linked...
  39. pmc Conservation of the biotin regulon and the BirA regulatory signal in Eubacteria and Archaea
    Dmitry A Rodionov
    State Scientific Center GosNIIGenetika, Moscow 113545, Russia
    Genome Res 12:1507-16. 2002
    ..BirA is the first example of a transcriptional regulator with a conserved binding signal in eubacteria and archaea...
  40. doi Mycobacteriophages: genes and genomes
    Graham F Hatfull
    Pittsburgh Bacteriophage Institute, Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Annu Rev Microbiol 64:331-56. 2010
    ..Mycobacteriophages have provided key tools for tuberculosis genetics, and new methods for simple construction of mycobacteriophage recombinants will facilitate postgenomic explorations into mycobacteriophage biology...
  41. pmc Fragile regions and not functional constraints predominate in shaping gene organization in the genus Drosophila
    Marcin von Grotthuss
    Department of Ecology and Evolutionary Biology, University of California Irvine, Irvine, California 92697, USA
    Genome Res 20:1084-96. 2010
    ..Both gene order conservation and breakpoint reuse can result from the existence of functional constraints on where chromosomal ..
  42. pmc The determinants of gene order conservation in yeasts
    Juan F Poyatos
    Logic of Genomic Systems Laboratory, Spanish National Biotechnology Centre, Centro Superior de Investigaciones Científicas CSIC, Darwin 3, Campus de Cantoblanco, Madrid 28049, Spain
    Genome Biol 8:R233. 2007
    ....
  43. ncbi The biosynthesis and regulation of bacterial prodiginines
    Neil R Williamson
    Department of Biochemistry, Tennis Court Road, University of Cambridge, UK
    Nat Rev Microbiol 4:887-99. 2006
    ..However, research into the biology of pigment production will stimulate interest in the bioengineering of strains to synthesize useful prodiginine derivatives...
  44. pmc Gene content and virtual gene order of barley chromosome 1H
    Klaus F X Mayer
    Munich Information Center for Protein Sequences Institute for Bioinformatics and Systems Biology, Helmholtz Zentrum Munich, German Research Center for Environmental Health, 85764 Neuherberg, Germany
    Plant Physiol 151:496-505. 2009
    ..Thus, integration of genomic, transcriptomic, and synteny-derived information represents a major step toward developing reference sequences of chromosomes and complete genomes of the most important plant tribe for mankind...
  45. pmc Multidrug-resistant Salmonella enterica serovar paratyphi A harbors IncHI1 plasmids similar to those found in serovar typhi
    Kathryn E Holt
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    J Bacteriol 189:4257-64. 2007
    ..Our data show that these serovar Typhi and Paratyphi A IncHI1 plasmids share highly conserved core DNA and have acquired similar mobile elements encoding antibiotic resistance genes in past decades...
  46. ncbi The mitochondrial DNA of land plants: peculiarities in phylogenetic perspective
    Volker Knoop
    IZMB Institut für Zelluläre und Molekulare Botanik, Universitat Bonn, Kirschallee 1, Bonn, Germany
    Curr Genet 46:123-39. 2004
    ..This review attempts to summarize the unique aspects of land plant mitochondrial evolution from a phylogenetic perspective...
  47. pmc A gene-based linkage map for Bicyclus anynana butterflies allows for a comprehensive analysis of synteny with the lepidopteran reference genome
    Patricia Beldade
    Institute of Biology, Leiden University, Leiden, The Netherlands
    PLoS Genet 5:e1000366. 2009
    ..This is discussed in relation to the identification of the loci contributing to color pattern evolution in butterflies...
  48. ncbi The complete chloroplast genome sequence of Pelargonium x hortorum: organization and evolution of the largest and most highly rearranged chloroplast genome of land plants
    Timothy W Chumley
    The University of Texas at Austin, TX, USA
    Mol Biol Evol 23:2175-90. 2006
    ..We propose simple models that account for the major rearrangements with a minimum of 8 IR boundary changes and 12 inversions in addition to several insertions of duplicated sequence...
  49. doi The first complete mitochondrial genome sequences of Amblypygi (Chelicerata: Arachnida) reveal conservation of the ancestral arthropod gene order
    Kathrin Fahrein
    Department of Biology, Koenigin Luise Str 1 3, D 14195 Berlin, Germany
    Genome 52:456-66. 2009
    ..Mitochondrial genomes provide an additional large data set of phylogenetic information (sequences, gene order, RNA secondary structure), but in arachnids, mitochondrial genome data are missing for some of the major orders...
  50. ncbi The complete sequence and gene organization of the mitochondrial genome of the gadilid scaphopod Siphonondentalium lobatum (Mollusca)
    Hermann Dreyer
    Institute of Zoology, University of Vienna, Althanstr 14, A 1090 Vienna, Austria
    Mol Phylogenet Evol 31:605-17. 2004
    ..different from all other known molluscan mitochondrial genomes and shows low similarity even to an unpublished gene order of a dentaliid scaphopod...
  51. pmc Molecular characterization of a variant of Bacillus anthracis-specific phage AP50 with improved bacteriolytic activity
    Shanmuga Sozhamannan
    Naval Medical Research Center, Silver Spring, Maryland 20910, USA
    Appl Environ Microbiol 74:6792-6. 2008
    ..Spontaneous AP50c-resistant B. anthracis mutants exhibit a mucoid colony phenotype...
  52. ncbi An association study between polymorphism of L1CAM gene and schizophrenia in a Japanese sample
    A Kurumaji
    Department of Neuropsychiatry, Tokyo Medical and Dental University School of Medicine, Japan
    Am J Med Genet 105:99-104. 2001
    ..These results suggest that the polymorphism in intron 25 plays a role in the genetic predisposition of male schizophrenia in the Japanese sample...
  53. doi Contracaecum rudolphii B: gene content, arrangement and composition of its complete mitochondrial genome compared with Anisakis simplex s.l
    Rui Qing Lin
    State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China
    Exp Parasitol 130:135-40. 2012
    ..This genome contains a high A+T (70.5%) content. The mt gene order for C. rudolphii B is the same as those for A. simplex s.l...
  54. pmc Autoregulation of convergent RNAi genes in fission yeast
    Monika Gullerova
    Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom
    Genes Dev 25:556-68. 2011
    ..Our results emphasize the significance of gene orientation for correct RNAi gene expression, and suggest a role for cell cycle-dependent formation of RNAi CG heterochromatin in cellular integrity...
  55. doi The complete mitochondrial genome of Setaria digitata (Nematoda: Filarioidea): Mitochondrial gene content, arrangement and composition compared with other nematodes
    Lalani Yatawara
    Department of Environmental Health Sciences, Kochi Medical School, Oko, Nankoku City, Japan
    Mol Biochem Parasitol 173:32-8. 2010
    ..This genome contains a high A+T (75.1%) content and low G+C content (24.9%). The mt gene order for S. digitata is the same as those for O. volvulus, D. immitis and B...
  56. doi Analysis of gene order evolution beyond single-copy genes
    Nadia El-Mabrouk
    Département d informatique et de recherche opérationnelle, Universite de Montreal, Montreal, QC, Canada
    Methods Mol Biol 855:397-429. 2012
    ....
  57. pmc Distinctive mitochondrial genome of Calanoid copepod Calanus sinicus with multiple large non-coding regions and reshuffled gene order: useful molecular markers for phylogenetic and population studies
    Wang Minxiao
    KLMEES and JBMERS, Institute of Oceanology, Chinese Academy of Sciences, 7 Nanhai Road, Qingdao 266071, China
    BMC Genomics 12:73. 2011
    ..As they are genome-level informative, mitochondrial DNA sequences can be used as markers for population genetic studies and phylogenetic studies...
  58. doi Rare genomic changes and mitochondrial sequences provide independent support for congruent relationships among the sea spiders (Arthropoda, Pycnogonida)
    Susan E Masta
    Department of Biology, Portland State University, Portland, OR 97207, USA
    Mol Phylogenet Evol 57:59-70. 2010
    ..b>Gene order and tRNA secondary structure characters provide independent lines of evidence for these inferred phylogenetic ..
  59. pmc Bacterial syntenies: an exact approach with gene quorum
    Yves Pol Deniélou
    INRIA Grenoble Rhone Alpes, team BAMBOO, 655 avenue de l Europe, 38334 Montbonnot Cedex, France
    BMC Bioinformatics 12:193. 2011
    ..The automatic identification of syntenies across multiple species is a key step in comparative genomics that helps biologists shed light both on evolutionary and functional problems...
  60. pmc Conservation of gene order and content in the circular chromosomes of 'Candidatus Liberibacter asiaticus' and other Rhizobiales
    L David Kuykendall
    Molecular Plant Pathology Laboratory, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland, United States of America
    PLoS ONE 7:e34673. 2012
    ..Liberibacter asiaticus' genes not shared with other Rhizobiales are of bacteriophage origin. 'Ca. Liberibacter asiaticus' shares 11 genes with only Sinorhizobium meliloti and 12 genes are shared with only Bartonella henselae...
  61. ncbi Data mining pathogen genomes using GeneOrder and CoreGenes and CGUG: gene order, synteny and in silico proteomes
    Padmanabhan Mahadevan
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA E mail
    Int J Comput Biol Drug Des 2:100-14. 2009
    ..GeneOrder, CoreGenes and CGUG are web-based 'on-the-fly' tools that examine gene order and synteny, as well as proteomes for comparative genomics and for drug discovery and design targets...
  62. doi The complete mitochondrial genome of the hard clam Meretrix meretrix
    Chong Bo He
    The Key Laboratory of Marine Fishery Molecular Biology of Liaoning Province, Liaoning Ocean and Fisheries Science Research Institute, 50 Heishijiao Street, Dalian 116023, China
    Mol Biol Rep 38:3401-9. 2011
    ....
  63. pmc Ecdysozoan mitogenomics: evidence for a common origin of the legged invertebrates, the Panarthropoda
    Omar Rota-Stabelli
    Department of Genetics, Evolution and Environment, University College London, London, United Kingdom
    Genome Biol Evol 2:425-40. 2010
    ..Tardigrada mitochondrial genomes resemble those of the arthropods in term of the gene order and strand asymmetry, whereas Onychophora genomes are characterized by numerous gene order rearrangements and ..
  64. doi The complete mitochondrial genome of the grand jackknife clam, Solen grandis (Bivalvia: Solenidae): a novel gene order and unusual non-coding region
    Yang Yuan
    Fisheries College, Ocean University of China, Qingdao, China
    Mol Biol Rep 39:1287-92. 2012
    Molluscs in general, and bivalves in particular, exhibit an extraordinary degree of mitochondrial gene order variation when compared with other metazoans...
  65. pmc A survey of sRNA families in α-proteobacteria
    Coral Del Val
    CITIC UGR, Centro de Investigación en Tecnologías de la Información y de las Comunicaciones de la Universidad de Granada, Granada, Spain
    RNA Biol 9:119-29. 2012
    ..meliloti 1021. The distribution patterns of these sRNA families suggest major contributions of vertical inheritance and extensive ancestral duplication events to the evolution of sRNAs in plant-interacting bacteria...
  66. ncbi Three divergent mitochondrial genomes from California populations of the copepod Tigriopus californicus
    Ronald S Burton
    Marine Biology Research Division, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093 0202, USA
    Gene 403:53-9. 2007
    ..The functional significance, if any, of this repeat structure remains unknown...
  67. pmc A linear molecule with two large inverted repeats: the mitochondrial genome of the stramenopile Proteromonas lacertae
    Vicente Perez-Brocal
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Genome Biol Evol 2:257-66. 2010
    ..It remains unclear whether the virtually identical gene repertoires are the result of convergence or descent...
  68. pmc The mosaic structure of the symbiotic plasmid of Rhizobium etli CFN42 and its relation to other symbiotic genome compartments
    Victor Gonzalez
    Centro de Investigacion Sobre Fijacion de Nitrogeno, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico 62210
    Genome Biol 4:R36. 2003
    ..We report the complete sequence of the symbiotic plasmid of Rhizobium etli CFN42, a microsymbiont of beans, and a comparison with other SGC sequences available...
  69. doi The complete mitochondrial genome of the cyclopoid copepod Paracyclopina nana: a highly divergent genome with novel gene order and atypical gene numbers
    Jang Seu Ki
    Department of Chemistry, Hanyang University, Seoul, South Korea
    Gene 435:13-22. 2009
    ..the complete mitogenome of the cyclopoid copepod Paracyclopina nana with emphasis on the highly rearranged gene order and high divergence against published copepod mitogenomes. The P. nana mtDNA is 15,981 bp in length (70...
  70. pmc Two-partner secretion systems of Neisseria meningitidis associated with invasive clonal complexes
    Peter van Ulsen
    Department of Molecular Microbiology, Utrecht University, 3584 CH Utrecht, The Netherlands
    Infect Immun 76:4649-58. 2008
    ..Together, our data indicate that TPS systems may contribute to the virulence of N. meningitidis...
  71. ncbi Clustering of tissue-specific genes underlies much of the similarity in rates of protein evolution of linked genes
    Elizabeth J B Williams
    Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK
    J Mol Evol 54:511-8. 2002
    ..The distribution of placentally expressed genes, in contrast, does have an effect...
  72. doi The chloroplast genomes of the green algae Pedinomonas minor, Parachlorella kessleri, and Oocystis solitaria reveal a shared ancestry between the Pedinomonadales and Chlorellales
    Monique Turmel
    Departement de Biochimie et de Microbiologie, Universite Laval, Québec Québec Canada
    Mol Biol Evol 26:2317-31. 2009
    ..Our results further emphasize the importance of secondary reduction at both the cellular and genome levels during chlorophyte evolution...
  73. ncbi A 1,000-loci transcript map of the barley genome: new anchoring points for integrative grass genomics
    Nils Stein
    Leibniz Institute of Plant Genetics and Crop Plant Research IPK, Corrensstrasse 3, 06466, Gatersleben, Germany
    Theor Appl Genet 114:823-39. 2007
    ..It provides new anchor points for detailed studies in comparative grass genomics and will support future attempts towards the integration of genetic and physical mapping information...
  74. doi Characterization of 67 mitochondrial tRNA gene rearrangements in the Hymenoptera suggests that mitochondrial tRNA gene position is selectively neutral
    Mark Dowton
    Centre for Biomedical Sciences, School of Biological Sciences, University of Wollongong, NSW, Australia
    Mol Biol Evol 26:1607-17. 2009
    ..g., Orussus and Schlettererius). It is likely that only a small proportion of the total number of mitochondrial gene rearrangements that have occurred during the evolution of the Hymenoptera have been sampled in the present study...
  75. doi The mitochondrial genome sequence of Enterobius vermicularis (Nematoda: Oxyurida)--an idiosyncratic gene order and phylogenetic information for chromadorean nematodes
    Seokha Kang
    Department of Parasitology, College of Medicine, Chungbuk National University, Cheongju 361 763, Republic of Korea
    Gene 429:87-97. 2009
    ..Unlike the relatively conserved gene arrangement found for most chromadorean taxa, E. vermicularis mtDNA gene order is very unique, not sharing similarity to any other nematode species reported to date...
  76. ncbi A Drosophila model of mitochondrial DNA replication: proteins, genes and regulation
    Rafael Garesse
    Departamento de Bioquimica, Instituto de Investigaciones Biomedicas Alberto Sols CSIC UAM, Facultad de Medicina, Universidad Autonoma de Madrid, Madrid, Spain
    IUBMB Life 57:555-61. 2005
    ..It also presents a survey of cell and animal models under development to mimic the pathophysiology of human mitochondrial disorders...
  77. pmc Tunicate mitogenomics and phylogenetics: peculiarities of the Herdmania momus mitochondrial genome and support for the new chordate phylogeny
    Tiratha Raj Singh
    Department of Zoology, George S Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel
    BMC Genomics 10:534. 2009
    ..This peculiar evolutionary dynamics has hampered the reconstruction of tunicate phylogenetic relationships within chordates based on mitogenomic data...
  78. pmc The complete mitochondrial genome of the house dust mite Dermatophagoides pteronyssinus (Trouessart): a novel gene arrangement among arthropods
    Wannes Dermauw
    Department of Crop Protection, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium
    BMC Genomics 10:107. 2009
    ..In this study, we describe the mitochondrial genome of the European house dust mite Dermatophagoides pteronyssinus, the most important member of this largely neglected group...
  79. pmc The complete plastid genome sequence of Welwitschia mirabilis: an unusually compact plastome with accelerated divergence rates
    Skip R McCoy
    Biological Sciences, Central Washington University, Ellensburg, WA 98926 7537, USA
    BMC Evol Biol 8:130. 2008
    ....
  80. doi Genomic analysis of a novel integrative conjugative element in Vibrio cholerae
    Elisa Taviani
    Maryland Pathogen Research Institute, University of Maryland, College Park, MD, USA
    FEBS Lett 583:3630-6. 2009
    ..ICEVchB33 revealed a new genetic organization, different from other ICEs of the SXT/R391 family, demonstrating the genomic plasticity of these elements...
  81. pmc Phylogeny and mitochondrial gene order variation in Lophotrochozoa in the light of new mitogenomic data from Nemertea
    Lars Podsiadlowski
    Abteilung Evolutionsbiologie, Institut fur Evolutionsbiologie und Okologie, Universitat Bonn, Germany
    BMC Genomics 10:364. 2009
    ..g. Mollusca, Brachiozoa or Platyhelminthes. Mitochondrial genomes contributed well with sequence data and gene order characters to the deep metazoan phylogeny debate.
  82. doi Bird mitochondrial gene order: insight from 3 warbler mitochondrial genomes
    Tiratha Raj Singh
    Mol Biol Evol 25:475-7. 2008
    Two main gene orders exist in birds: the ancestral gene order and the remnant control region (CR) 2 gene order. These gene orders differ by the presence of 1 or 2 copies of the CR, respectively...
  83. ncbi The genome stability in Corynebacterium species due to lack of the recombinational repair system
    Yoji Nakamura
    Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics, Mishima, Japan
    Gene 317:149-55. 2003
    ..The genome stability in Corynebacterium species will give us hints of the speciation mechanism with the non-shuffled genome, particularly the importance of horizontal gene transfer and nucleotide substitution in the genome...
  84. doi Evaluation of the phylogenetic position of the sulfate-reducing bacterium Thermodesulfovibrio yellowstonii (phylum Nitrospirae) by means of gene order data from completely sequenced genomes
    Takashi Kunisawa
    Department of Applied Biological Science, Science University of Tokyo, Noda 278 8510, Japan
    Int J Syst Evol Microbiol 60:1090-102. 2010
    The phylogenetic placement of Thermodesulfovibrio yellowstonii was investigated on the basis of gene order data from completely sequenced bacterial genomes. T...
  85. pmc Chloroplast DNA sequence of the green alga Oedogonium cardiacum (Chlorophyceae): unique genome architecture, derived characters shared with the Chaetophorales and novel genes acquired through horizontal transfer
    Jean Simon Brouard
    Departement de Biochimie et de Microbiologie, Universite Laval, Quebec, QC G1V 0A6, Canada
    BMC Genomics 9:290. 2008
    ..We describe here the complete cpDNA sequence of Oedogonium cardiacum (Oedogoniales)...
  86. pmc The pseudogenes of Mycobacterium leprae reveal the functional relevance of gene order within operons
    Enrique M Muro
    Computational Biology and Data Mining Group, Max Delbruck Center for Molecular Medicine, Robert Rossle Strasse 10, 13125, Berlin, Germany
    Nucleic Acids Res 39:1732-8. 2011
    Almost 50 years following the discovery of the prokaryotic operon, the functional relevance of gene order within operons remains unclear...
  87. doi A novel mitochondrial gene order in shorebirds (Scolopacidae, Charadriiformes)
    Yvonne I Verkuil
    Centre of Ecological and Evolutionary Studies CEES, University of Groningen, Haren, The Netherlands
    Mol Phylogenet Evol 57:411-6. 2010
    ..birds has highly conserved features, with protein genes similar to mammals and amphibians, several variations in gene order around the hypervariable control region have been found...
  88. pmc Unusual conservation of mitochondrial gene order in Crassostrea oysters: evidence for recent speciation in Asia
    Jianfeng Ren
    Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China
    BMC Evol Biol 10:394. 2010
    ..iredalei and Saccostrea mordax) for a comprehensive analysis...
  89. pmc Analysis of gene order conservation in eukaryotes identifies transcriptionally and functionally linked genes
    Marcela Dávila López
    Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Goteborg, Sweden
    PLoS ONE 5:e10654. 2010
    The order of genes in eukaryotes is not entirely random. Studies of gene order conservation are important to understand genome evolution and to reveal mechanisms why certain neighboring genes are more difficult to separate during ..
  90. pmc The mitochondrial genome structure of Xenoturbella bocki (phylum Xenoturbellida) is ancestral within the deuterostomes
    Sarah J Bourlat
    Department of Invertebrate Zoology, Swedish Museum of Natural History, Stockholm, Sweden
    BMC Evol Biol 9:107. 2009
    ..As well as primary sequence data, rare genomic changes such as gene order, shared gene boundaries and genetic code changes, which are unlikely to have arisen through convergent evolution,..
  91. ncbi The complete mitochondrial genomes of the sea lily Gymnocrinus richeri and the feather star Phanogenia gracilis: signature nucleotide bias and unique nad4L gene rearrangement within crinoids
    Andrea Scouras
    Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada
    Mol Phylogenet Evol 39:323-34. 2006
    ..Smith, M.J., 2001. Mol. Biol. Evol. 18, 61-73). The mitochondrial gene order of the stalked crinoid G. richeri differs from that of F. serratissima and P...
  92. ncbi Multiple rounds of speciation associated with reciprocal gene loss in polyploid yeasts
    Devin R Scannell
    Smurfit Institute of Genetics, University of Dublin, Trinity College, Dublin 2, Ireland
    Nature 440:341-5. 2006
    ..We propose a simple, unified model in which a single mechanism--passive gene loss-enabled whole--genome duplication and led to the rapid emergence of new yeast species...
  93. ncbi The complete DNA sequence of the mitochondrial genome of the dermatophyte fungus Epidermophyton floccosum
    José Humberto M Tambor
    Instituto de Ciencias Biomedicas, Departamento de Microbiologia, Universidade de Sao Paulo, Av Prof Lineu Prestes, 1374, Ed Biomédicas II, Cidade Universitaria, CEP 05508 900, Sao Paulo, Brazil
    Curr Genet 49:302-8. 2006
    ..The mtDNA of E. floccosum has the same gene order as Trichophyton rubrum mtDNA, with the exception of some tRNA genes...
  94. pmc Global transcriptome analysis of the C57BL/6J mouse testis by SAGE: evidence for nonrandom gene order
    Petr Divina
    Institute of Molecular Genetics, Academy of Sciences of the Czech Republic and Center for Integrated Genomics, Videnska 1083, CZ 142 20, Prague 4, Czech Republic
    BMC Genomics 6:29. 2005
    ..An extensive bioinformatic analysis and comparison of SAGE transcriptomes of the total testis, testicular somatic cells and other mouse tissues was performed and the theory of male-biased gene accumulation on the X chromosome was tested...
  95. ncbi Comparative analysis of Phytophthora genes encoding secreted proteins reveals conserved synteny and lineage-specific gene duplications and deletions
    Rays H Y Jiang
    Laboratory of Phytopathology, Plant Sciences Group, Wageningen University, Binnenhaven 5, NL 6709 PD Wageningen, The Netherlands
    Mol Plant Microbe Interact 19:1311-21. 2006
    ..9-Mb sequence of P. ramorum. In these regions with conserved synteny, the gene order is largely similar; however, genome rearrangements also have occurred...
  96. pmc Highly conserved gene order and numerous novel repetitive elements in genomic regions linked to wing pattern variation in Heliconius butterflies
    Riccardo Papa
    Department of Biology, University of Puerto Rico Rio Piedras, San Juan, Puerto Rico
    BMC Genomics 9:345. 2008
    ..melpomene. To this end we have undertaken comparative mapping and targeted genomic sequencing in both species. This paper reports on a comparative analysis of genomic sequences linked to color pattern mimicry genes in Heliconius...
  97. ncbi The complete mitochondrial genomes of two common shrimps (Litopenaeus vannamei and Fenneropenaeus chinensis) and their phylogenomic considerations
    Xin Shen
    Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266071, China
    Gene 403:98-109. 2007
    ..In addition, the analyses of the average Ka/Ks in the 13 mitochondrial protein-coding genes of penaeid shrimps indicated a strong purifying selection within this group...
  98. pmc Inferring genome-scale rearrangement phylogeny and ancestral gene order: a Drosophila case study
    Arjun Bhutkar
    BioMolecular Engineering Research Center, Boston University, Cummington St, Boston, MA 02215, USA
    Genome Biol 8:R236. 2007
    ..biologically inspired computational approach for inferring genome-scale rearrangement phylogeny and ancestral gene order has been developed. This has been applied to eight Drosophila genomes...
  99. doi Long-range gene control and genetic disease
    Dirk A Kleinjan
    MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, United Kingdom
    Adv Genet 61:339-88. 2008
    ....
  100. pmc Dynamics of genome rearrangement in bacterial populations
    Aaron E Darling
    ARC Center of Excellence in Bioinformatics, The University of Queensland, St Lucia, Queensland, Australia
    PLoS Genet 4:e1000128. 2008
    ..Insight into the process of genomic rearrangement may further the understanding of pathogen population dynamics and selection on the architecture of circular bacterial chromosomes...
  101. ncbi Evolutionary origin and maintenance of coexpressed gene clusters in mammals
    Marie Semon
    Laboratoire de Biometrie et Biologie Evolutive, UMR CNRS 5558, Universite Claude Bernard Lyon 1, Villeurbanne, France
    Mol Biol Evol 23:1715-23. 2006
    b>Gene order is not random with regard to gene expression in mammals: coexpressed genes, and in particular housekeeping genes, are clustered along chromosomes more often than expected by chance...

Research Grants69

  1. REGULATION AND MHC DEPENDENCE OF GAMMA DELTA T CELLS
    David Raulet; Fiscal Year: 2005
    ..Specific Aim 3. To dissect the role of gene order, domains, and flanking cis-acting regulatory sequences in determining the fetal thymic V-gamma gene ..
  2. GENOMIC ANALYSIS OF ZEBRAFISH DEVELOPMENT
    John Postlethwait; Fiscal Year: 2002
    ..These will provide candidate genes for mutations and will delineate chromosome segments in which gene order has been conserved in vertebrate evolution...
  3. Baboon Model for Genetics of Human Generalized Epilepsy
    Jeff Williams; Fiscal Year: 2007
    ..The evolutionary proximity of baboon and human, and the high degree of conservation of gene order between these species, imply that genetic factors identified in the baboon genome will be directly relevant to ..
  4. Structure and activity of Escherichia coli chromosome
    Arkady Khodursky; Fiscal Year: 2007
    ..abstract_text> ..
  5. Remodeling SARS Coronavirus Genome Regulatory Networks
    Ralph Baric; Fiscal Year: 2004
    ..Moreover, we and others have shown that coronaviruses tolerate gene order rearrangements, but as a consequence are attenuated in replication efficiency and pathogenesis...
  6. REVERSE GENETICS WITH A CORONAVIRUS INFECTIOUS CONSTRUCT
    Ralph Baric; Fiscal Year: 2004
    ..we will use reverse genetics and the full length TGE construct to systematically address the role of gene order, cis and trans acting regulatory sequences, and N gene function in coronavirus transcription and replication...
  7. Regulation of sleep-like behavior in C. elegans
    David Raizen; Fiscal Year: 2009
    ..In addition, we will assess the gene order relationship between egl-4 and pde-4 is regulating sensory gating...
  8. Regulation of sleep-like behavior in C. elegans
    DAVID MENASSAH RAIZEN; Fiscal Year: 2010
    ..In addition, we will assess the gene order relationship between egl-4 and pde-4 is regulating sensory gating...
  9. IMMUNOGLOBULIN GENE ARRANGEMENT EXPRESSION IN LEUKEMIA
    Geoffrey Neale; Fiscal Year: 2000
    ....
  10. ZEBRAFISH MAP FOR COMPARATIVE AND FUNCTIONAL GENOMICS
    WILLIAM TALBOT; Fiscal Year: 2002
    ..between zebrafish and human genomes by identifying the boundaries of conserved chromosomal segments and defining gene order within these segments...
  11. Data-driven Computational Modeling of the Growth and Spread of Viruses
    John Yin; Fiscal Year: 2007
    ..model using experimental data from a panel of recombinant VSV strains, and (3) employ the model to predict how gene order affects VSV growth...
  12. Canine Brain Tumors - A New Model for Gene Discovery
    Matthew Breen; Fiscal Year: 2006
    ..Humans and dogs have similar physiology, share extensive genome homology with a high degree of preserved gene order, and are exposed to the same environment...
  13. Control of Mammalian Meiotic Recombination
    Terry Ashley; Fiscal Year: 2007
    ..Genetic linkage maps provide information on gene order and crossover frequency but not on the influence of chromosome structure on recombination, while chiasmata ..