controlled environment

Summary

Summary: A state in which the environs of hospitals, laboratories, domestic and animal housing, work places, spacecraft, and other surroundings are under technological control with regard to air conditioning, heating, lighting, humidity, ventilation, and other ambient features. The concept includes control of atmospheric composition. (From Jane's Aerospace Dictionary, 3d ed)

Top Publications

  1. ncbi The paradox of an energy-efficient home: is it good or bad for health?
    George Richardson
    Faculty of Health and Social Work, University of Plymouth
    Community Pract 79:397-9. 2006
  2. ncbi Flavonoid concentrations in three grass species and a sedge grown in the field and under controlled environment conditions in response to enhanced UV-B radiation
    J van de Staaij
    Department of Systems Ecology, Institute of Ecological Science, Faculty of Biology, Vrije Universiteit, De Boelelaan 1087, 1081 HV Amsterdam, The Netherlands
    J Photochem Photobiol B 66:21-9. 2002
  3. pmc Temporal and spatial dispersal of cladobotryum conidia in the controlled environment of a mushroom growing room
    Bruce Adie
    Teagasc, Kinsealy Research and Development Centre, Malahide Road, Kinsealy, Dublin 17, Ireland
    Appl Environ Microbiol 72:7212-7. 2006
  4. ncbi Study of smoke aerosols under a controlled environment by using dynamic light scattering
    Ravindra Pratap Singh
    Physical Research Laboratory, Navrangpura, Ahmedabad, India
    Appl Opt 45:2217-21. 2006
  5. ncbi Culturing primary brain astrocytes under a fully controlled environment in a novel bioreactor
    Sónia Sá Santos
    Instituto de Biologia Experimental e Tecnológica Instituto de Tecnologia Quimica e Biológica IBET ITQB, 2781 901 Oeiras, Portugal
    J Neurosci Res 79:26-32. 2005
  6. ncbi Simulated tennis matchplay in a controlled environment
    P R Davey
    School of Applied Sciences, South Bank University, 103 Borough Road, London SE1 0AA, UK
    J Sports Sci 21:459-67. 2003
  7. ncbi Interaction between drought and chronic high temperature during kernel filling in wheat in a controlled environment
    Ian F Wardlaw
    CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia
    Ann Bot 90:469-76. 2002
  8. ncbi Ground performance of air conditioning and water recycle system for a Space Plant Box
    A Tani
    School of High-Technology for Human Welfare, Tokai University, Nishino, Numazu, Shizuoka, 410-0395, Japan
    Adv Space Res 27:1557-62. 2001
  9. ncbi [Optimization analysis of ventilation and dehumidification in manned spacecraft]
    X Ji
    Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China
    Space Med Med Eng (Beijing) 14:272-6. 2001
  10. ncbi Evaluation of a new mobile system for protecting immune-suppressed patients against airborne contamination
    Jean Louis Poirot
    Hopital Saint Antoine, Laboratoire de Parasitologie Mycologie, Paris, France
    Am J Infect Control 35:460-6. 2007

Research Grants

  1. A randomized trial of bariatric surgery for the treatment of sleep apnea
    Sanjay R Patel; Fiscal Year: 2010
  2. Plant-Derived hepatitis B Vaccine from Biomanufacturing System to Clinical Trial
    Robert Britt; Fiscal Year: 2009
  3. Adjustable balloon implant for medialization thyroplasty
    Matthew R Hoffman; Fiscal Year: 2012
  4. Reflex Contributions to Joint Stability
    YASIN DHAHER; Fiscal Year: 2004
  5. Reflex Contributions to Joint Stability
    YASIN DHAHER; Fiscal Year: 2005
  6. Reflex Contributions to Joint Stability
    YASIN DHAHER; Fiscal Year: 2007
  7. Reflex Contributions to Joint Stability
    YASIN DHAHER; Fiscal Year: 2006
  8. NEURAL CONTROL OF THE GALLBLADDER
    Gary M Mawe; Fiscal Year: 2010
  9. NEURAL CONTROL OF THE GALLBLADDER
    Gary Mawe; Fiscal Year: 2009
  10. CHEMORECEPTOR ACTIVITY OF THE CAROTID BODY
    Carlos Eyzaguirre; Fiscal Year: 1990

Detail Information

Publications194 found, 100 shown here

  1. ncbi The paradox of an energy-efficient home: is it good or bad for health?
    George Richardson
    Faculty of Health and Social Work, University of Plymouth
    Community Pract 79:397-9. 2006
    ..The article argues that householders need to adapt their lifestyles and house management methods to their new indoor environment. It discusses a range of ways in which health professionals can help...
  2. ncbi Flavonoid concentrations in three grass species and a sedge grown in the field and under controlled environment conditions in response to enhanced UV-B radiation
    J van de Staaij
    Department of Systems Ecology, Institute of Ecological Science, Faculty of Biology, Vrije Universiteit, De Boelelaan 1087, 1081 HV Amsterdam, The Netherlands
    J Photochem Photobiol B 66:21-9. 2002
    ..These results indicate that constitutive levels of flavonoids in these grass and sedge species are adequately high to protect them against ambient and elevated levels of solar UV-B radiation...
  3. pmc Temporal and spatial dispersal of cladobotryum conidia in the controlled environment of a mushroom growing room
    Bruce Adie
    Teagasc, Kinsealy Research and Development Centre, Malahide Road, Kinsealy, Dublin 17, Ireland
    Appl Environ Microbiol 72:7212-7. 2006
    ..Prevention of airborne conidial release and distribution is essential to avoid mushroom spotting symptoms, secondary colonies, and early crop termination...
  4. ncbi Study of smoke aerosols under a controlled environment by using dynamic light scattering
    Ravindra Pratap Singh
    Physical Research Laboratory, Navrangpura, Ahmedabad, India
    Appl Opt 45:2217-21. 2006
    ..The effects of temperature and concentration on aerosol size were also observed. We found that aerosol size increases almost linearly with an increase in concentration but decreases with an increase in temperature...
  5. ncbi Culturing primary brain astrocytes under a fully controlled environment in a novel bioreactor
    Sónia Sá Santos
    Instituto de Biologia Experimental e Tecnológica Instituto de Tecnologia Quimica e Biológica IBET ITQB, 2781 901 Oeiras, Portugal
    J Neurosci Res 79:26-32. 2005
    We report the first approach for growth and maintenance of primary astrocytes on a fully controlled environment. For this purpose, cells were immobilized in Cytodex microcarriers and grown in a stirred tank bioreactor...
  6. ncbi Simulated tennis matchplay in a controlled environment
    P R Davey
    School of Applied Sciences, South Bank University, 103 Borough Road, London SE1 0AA, UK
    J Sports Sci 21:459-67. 2003
    ..simulating similar physiological responses in Part A to 'actual' matchplay on a 'category 2' surface, in a controlled environment; it was also a sensitive evaluation tool of skilled performance in Part B...
  7. ncbi Interaction between drought and chronic high temperature during kernel filling in wheat in a controlled environment
    Ian F Wardlaw
    CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia
    Ann Bot 90:469-76. 2002
    ....
  8. ncbi Ground performance of air conditioning and water recycle system for a Space Plant Box
    A Tani
    School of High-Technology for Human Welfare, Tokai University, Nishino, Numazu, Shizuoka, 410-0395, Japan
    Adv Space Res 27:1557-62. 2001
    ..The simple, air conditioning and water recycle system for the Space Plant Box showed good performance through a barley (Hordeum vulgare L.) growth experiment...
  9. ncbi [Optimization analysis of ventilation and dehumidification in manned spacecraft]
    X Ji
    Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China
    Space Med Med Eng (Beijing) 14:272-6. 2001
    ..But the system structure of this design was relatively complex. Conclusion: Mass and power consumption of the system could be reduced by selecting appropriate parameters and adopting the measures of optimization...
  10. ncbi Evaluation of a new mobile system for protecting immune-suppressed patients against airborne contamination
    Jean Louis Poirot
    Hopital Saint Antoine, Laboratoire de Parasitologie Mycologie, Paris, France
    Am J Infect Control 35:460-6. 2007
    ..Providing patient protection from such airborne threats requires costly and high-maintenance facilities. We herein evaluate a new self-contained mobile unit as an alternative for creating a patient protective environment...
  11. ncbi Impact of portable air filtration units on exposure of haematology-oncology patients to airborne Aspergillus fumigatus spores under field conditions
    S Engelhart
    Institute of Hygiene and Public Health, University of Bonn, Bonn, Germany
    J Hosp Infect 54:300-4. 2003
    ..We conclude that under field conditions this air filtration unit cannot be recommended for prevention of invasive aspergillosis in neutropenic haematology-oncology patients...
  12. ncbi Hardware of the flight experiment "Quail-SK" transport incubator
    V Sabo
    Institute of Animal Biochemistry and Genetics SAS, Ivanka pri Dunaji, Slovak Republic
    Acta Astronaut 49:41-6. 2001
    ..Device description, diagrams, and experimental results are presented in this paper...
  13. ncbi Size relationship between airborne viable bacteria and particles in a controlled indoor environment study
    K W Tham
    Department of Building, School of Design and Environment, National University of Singapore, Singapore
    Indoor Air 15:48-57. 2005
    ..Viability of bacteria was shown to be affected by thermal effects. The percentages of particles that were viable bacteria at the different sizes were all found to be very low (<1%)...
  14. ncbi [Prevention of prosthesis infections]
    Peter Holmberg Jørgensen
    Arhus Universitetshospital, Arhus Sygehus, ortopaedkirurgisk afdeling, Tumor infektionssektoren, Arhus C
    Ugeskr Laeger 169:4159-63. 2007
    ..Laminary flow reduces the risk of prosthesis infection but there is no clear evidence of any effect to concomitant antibiotic prophylaxis...
  15. ncbi Ventilation performance in the operating theatre against airborne infection: numerical study on an ultra-clean system
    T T Chow
    Division of Building Science and Technology, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, China
    J Hosp Infect 59:138-47. 2005
    ..This paper stresses that a successful outcome in preventing airborne infection depends as much on resolving human factors as on overcoming technical obstacles...
  16. pmc The application of ultraviolet germicidal irradiation to control transmission of airborne disease: bioterrorism countermeasure
    Philip W Brickner
    Saint Vincent s Catholic Medical Centers, St Vincent s Hospital Manhattan NY, Dept of Community Medicine, New York, NY 10011, USA
    Public Health Rep 118:99-114. 2003
    ..In this article, the authors provide an overview of air disinfection technologies, and an in-depth analysis of UVGI-its history, applications, and effectiveness...
  17. ncbi [Numerical study of the effects (correction of efects) of size of inlets and outlets of ventilation system in experimental space station cabin]
    H Wu
    Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China
    Space Med Med Eng (Beijing) 14:268-71. 2001
    ..Result: The taper inlet and crescent outlet had the best integrated performance. Conclusion: The use of variational section was recommended in designing and building of ventilation project in space station cabin...
  18. ncbi Operating room management: operative suite considerations, infection control
    Maria D Allo
    Department of Surgery, Santa Clara Valley Medical Center, 751 South Bascom Avenue, San Jose, CA 95128, USA
    Surg Clin North Am 85:1291-7, xii. 2005
    ..Guidelines should be consulted and incorporated into each operating room's policies and procedures...
  19. ncbi [Performances of different types of airflow system in operating theatre]
    D Talon
    Service d Hygiène Hospitalière, CHU Jean Minjoz, Boulevard Fleming, 25030 Besancon Cedex, France
    Ann Chir 131:316-21. 2006
    ..To compare the performance of various types of airflow system in operating theatre...
  20. ncbi Impact of environmental factors on efficacy of upper-room air ultraviolet germicidal irradiation for inactivating airborne mycobacteria
    Peng Xu
    Department of Civil, Environmental, and Architectural Engineering, 428 UCB, University of Colorado, Boulder, Colorado 80309 0428, USA
    Environ Sci Technol 39:9656-64. 2005
    ..The inactivation rate increased linearly with effective UV fluence rate up to 5 microW cm(-2); an increase in the fluence rate above this level did not yield a proportional increase in inactivation rate...
  21. ncbi Control and management of hospital indoor air quality
    Michael Leung
    Department of Mechanical Engineering, The University of Hong Kong, Kowloon, Hong Kong
    Med Sci Monit 12:SR17-23. 2006
    ..The aim here is to recommend effective guidelines for the control and management of hospital IAQ...
  22. ncbi Improving performance of HVAC systems to reduce exposure to aerosolized infectious agents in buildings; recommendations to reduce risks posed by biological attacks
    Penny J Hitchcock
    Center for Biosecurity of UPMC, Baltimore, MD 21202, USA
    Biosecur Bioterror 4:41-54. 2006
    ....
  23. ncbi [Ophthalmic operating theatre--chance of limiting contamination and infection risk. Part I. Decontamination of the microbial air pollution]
    Józef Kałuzny
    Z Katedry i Kliniki Okulistycznej Akademii Medycznej w Bydgoszczy
    Klin Oczna 110:102-7. 2008
    ..These decontamination methods make it possible to achieve appropriate microbiological standards when the appliance is properly used...
  24. ncbi Risk of bioaerosol contamination with Aspergillus species before and after cleaning in rooms filtered with high-efficiency particulate air filters that house patients with hematologic malignancy
    Linda D Lee
    Department of Environmental Health and Safety, The University of Texas M D Anderson Cancer Center, Houston, TX 77230, USA
    Infect Control Hosp Epidemiol 28:1066-70. 2007
    ....
  25. ncbi Containment testing of isolation rooms
    J P Rydock
    Norwegian Building Research Institute, Høgskoleringen 7, NO 7491 Trondheim, Oslo, Norway
    J Hosp Infect 57:228-32. 2004
    ..The study also demonstrates that the tracer testing procedure yields comparable results for equivalent isolation room suites, suggesting good reproducibility of the testing method...
  26. ncbi A performance assessment of airborne infection isolation rooms
    Stefan A Saravia
    Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
    Am J Infect Control 35:324-31. 2007
    ..Airborne infection isolation rooms (AIIRs) help prevent the spread of infectious agents in hospitals. The performance of 678 AIIRs was evaluated and compared with construction design guidelines...
  27. ncbi Static electric charge may contribute to infections in bone marrow transplant wards
    J E Allen
    J Hosp Infect 54:80-1. 2003
  28. ncbi Positive-pressure isolation and the prevention of invasive aspergillosis. What is the evidence?
    H Humphreys
    Department of Clinical Microbiology, RCSI Education and Research Centre, Beaumont Hospital, Dublin, Ireland
    J Hosp Infect 56:93-100; quiz 163. 2004
    ....
  29. ncbi Aerobiology in the operating room and its implications for working standards
    B Friberg
    Department of Nursing, Umea University, Umea, Sweden
    Proc Inst Mech Eng H 219:153-60. 2005
    ..In the areas important for surgical asepsis the turbulent ventilation systems yielded highly significant correlation between air and surface contamination (p < 0.02-0.0006). No such correlation existed in the LAF systems...
  30. ncbi Ventilation performance in operating theatres against airborne infection: review of research activities and practical guidance
    T T Chow
    Division of Building Science and Technology, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, People s Republic of China
    J Hosp Infect 56:85-92. 2004
    ..The basic principles and current practice applying to operating theatre ventilation studies are introduced...
  31. ncbi The Soviet-Russian space suits a historical overview of the 1960's
    A Ingemar Skoog
    Astrium GmbH, Friedrichshafen, FRG
    Acta Astronaut 51:113-31. 2002
    ..This paper covers the space suit development in the Soviet Union in the 1960's and the experience used from the pre-space era...
  32. ncbi Considerations of design for life support systems
    Akira Ashida
    Institute for Environmental Sciences, Obuchi, Rokkasho mura, Kamikita gun Aomori, Japan
    Adv Space Res 31:1805-9. 2003
    ..2) The system operation method in trouble, which relates to maintainability. (3) The system metamorphosis according to new technologies. (4) Route minimization of material flow that leads to an optimum system layout...
  33. ncbi [Mass optimization of thermal network model of coupled dual-loop thermal control system in spacecraft]
    X R Zhang
    Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China
    Space Med Med Eng (Beijing) 14:277-81. 2001
    ..Conclusion: Reasonable design of these parameters were very important for reducing the system mass...
  34. ncbi Ultraclean air for prevention of postoperative infection after posterior spinal fusion with instrumentation: a comparison between surgeries performed with and without a vertical exponential filtered air-flow system
    Marcelo F Gruenberg
    Institute of Orthopaedics Carlos E Ottolenghi, Italian Hospital of Buenos Aires, Buenos Aires, Argentina
    Spine (Phila Pa 1976) 29:2330-4. 2004
    ..This study retrospectively compared infection rates between adult patients after posterior spinal instrumentation procedures performed in a conventional versus an ultraclean air operating room...
  35. ncbi Wrapping it up. The hospital's first line of defense against moisture
    Carl C Schultz
    URS Corp, Columbus, OH, USA
    Health Facil Manage 19:23-7. 2006
  36. ncbi Convection warmers--a possible source of contamination in laminar airflow operating theatres?
    N Tumia
    Department of Orthopaedics, Aberdeen University Medical School, Foresterhill, Aberdeen, Scotland, AB9 2ZB, UK
    J Hosp Infect 52:171-4. 2002
    ..By far the greatest effect on numbers was movement and presence of the patient and theatre staff in the theatre...
  37. ncbi Conversion of operating theatre from positive to negative pressure environment
    T T Chow
    Division of Building Science and Technology, City University of Hong Kong, Hong Kong SAR, China
    J Hosp Infect 64:371-8. 2006
    ..The simulation results show that the physical environment and the dispersion pattern of bacteria in the negative pressure theatre were as good as, if not better than, those in the original positive pressure design...
  38. ncbi The addition of a mobile ultra-clean exponential laminar airflow screen to conventional operating room ventilation reduces bacterial contamination to operating box levels
    S Friberg
    Department of Orthopaedics, Umea University, S 901 85, Umea, Sweden
    J Hosp Infect 55:92-7. 2003
    ....
  39. ncbi A computer evaluation of ventilation performance in a negative-pressure operating theater
    Tin tai Chow
    Division of Building Science and Technology, City University of Hong Kong, China
    Anesth Analg 103:913-8. 2006
    ..In this article, we introduce its ventilation design and evaluate the airflow performance in relation to different combinations of medical lamp configurations and modes of launching infectious particles into the room air...
  40. ncbi The influence of air conditioning, humidity, temperature and other household characteristics on mite allergen concentrations in the northeastern United States
    R T van Strien
    Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University School of Medicine, 1 Church Street 6th floor, New Haven, CT 06510, USA
    Allergy 59:645-52. 2004
    ..Information about the influence of housing and occupant characteristics on mite allergen concentrations is crucial to determine which methods could be used to decrease exposure of susceptible subjects...
  41. ncbi Making the numbers add up
    Eric Hudson
    Fluke Corporation, Everett, Wash, USA
    Occup Health Saf 75:150, 152-5, 178. 2006
  42. ncbi Technical review of the Laboratory Biosphere closed ecological system facility
    W F Dempster
    Biosphere Technologies, Sante Fe, NM 87508, USA
    Adv Space Res 34:1477-82. 2004
    ..The focus of this initial trial was system testing to confirm functionality and identify any necessary modifications or improvements. This paper describes the organizational and physical features of the Laboratory Biosphere...
  43. ncbi Crop yield and light/energy efficiency in a closed ecological system: Laboratory Biosphere experiments with wheat and sweet potato
    M Nelson
    Institute of Ecotechnics, London, UK
    Adv Space Res 35:1539-43. 2005
    ..Compared to projected yields for the Mars on Earth life support system, these wheat yields were about 15% higher, and the sweet potato yields averaged over 80% higher...
  44. ncbi [Air quality monitoring on the International Space Station]
    A A Pakhomova
    Aviakosm Ekolog Med 40:46-9. 2006
    ..g. local fire, toxic leak) air control. The ISS air quality has suited to the adopted standards and crew safety requirements. Yet, there is a broad field of action toward improvement of the space cabin air monitoring...
  45. ncbi MRI-compatible incubation chamber for cell culture experiments
    Nina F Schwenzer
    Division of Diagnostic Radiology, Department of Radiology, Klinikum der Eberhard Karls Universität Tübingen, Tubingen, Germany
    J Magn Reson Imaging 23:70-6. 2006
    ..To develop an incubation chamber that is compatible with MRI, while avoiding sources of error due to the experimental setup...
  46. ncbi Quantitative and qualitative analysis of microorganisms in an assisted reproductive technology facility
    Jason L Herlong
    University of South Carolina School of Medicine, Columbia, South Carolina, USA
    Fertil Steril 89:847-53. 2008
    ..To perform a quantitative and qualitative analysis of the environmental microorganisms associated with two assisted reproductive technology (ART) laboratories...
  47. ncbi Fundamental factors affecting upper-room ultraviolet germicidal irradiation - part I. Experimental
    Melvin First
    Harvard School of Public Health Department of Environmental Health, Boston, Massachusetts 02115, USA
    J Occup Environ Hyg 4:321-31. 2007
    ..A conclusion of the study is that an upper-room ultraviolet installation is a complex system that requires careful integration of UV luminaires, UV power, and room ventilation arrangements...
  48. ncbi Adaptive environmental control for optimal results during plant microgravity experiments
    P Kostov
    Space Research Institute, Bulgarian Academy of Sciences, Sofia, Bulgaria
    Acta Astronaut 51:213-20. 2002
    ..A conceptual block-diagram of the SVET-3 SG is presented...
  49. ncbi Evaluating and optimizing horticultural regimes in space plant growth facilities
    Y A Berkovich
    Institute of Biomedical Problems, Moscow, Russia
    Adv Space Res 34:1612-8. 2004
    ..The criterion reflects directly on the consumption of onboard resources for crop production...
  50. ncbi [Appraisal and analysis of heat removing characteristic of liquid cooling garment using thermal manikin]
    W X Zhang
    Institute of Space Medico-Engineering, Beijing 100094, China
    Space Med Med Eng (Beijing) 14:257-60. 2001
    ..Conclusion: The design of the LCG for the EVA space suit was found to be reasonable. The flow rate regulation range was too narrow, and the change of heat removing capacity depended on the change of inlet temperature...
  51. ncbi [Environmental control and life support system of spacecraft]
    Xue fu Shen
    Institute of Space Medico Engineering, Beijing, China
    Space Med Med Eng (Beijing) 16:543-9. 2003
    ..It is a key technology must be broken through for the realization of manned space flight. Its functions, technical requirements and main technology were reviewed in this paper. Its test verification was also discussed...
  52. ncbi Developmental status of Aquatic Animal Experiment Facility, Aquatic Habitat (AQH), for International Space Station
    Toru Sakimura
    Mitsubishi Heavy Industries, Ltd Kobe Shipyard and Machinery Works, Kobe, Japan
    Biol Sci Space 17:240-1. 2003
    ..Currently the prototype model of water circulation system and specimen chambers have been manufactured and biological compatibility tests are being conducted with medaka. The current developmental status of AQH is summarized...
  53. ncbi The Biotechnology Facility for International Space Station
    Thomas Goodwin
    NASA Johnson Space Center, Biological Systems Office, Houston, TX 77058, USA
    J Gravit Physiol 11:75-80. 2004
    ..The BTF will support continuous operation, which will allow performance of long-duration experiments and will significantly increase the on-orbit science throughput...
  54. ncbi Development and verification of hardware for life science experiments in the Japanese Experiment Module "Kibo" on the International Space Station
    Noriaki Ishioka
    Department of Space Biology and Microgravity Science, Institute of Space and Astronautical Science
    J Gravit Physiol 11:81-91. 2004
    ..The biological experiment units (BEU) are designed to run individual experiments using the CBEF and the CB. A plant experiment unit (PEU) and two cell experiment units (CEU type1 and type2) for the BEU have been developed...
  55. ncbi Continuous microbiological air monitoring for aseptic filling lines
    Karen Ginsbury
    PDA J Pharm Sci Technol 61:225. 2007
  56. ncbi An efficient analytical method for particle counting in evaluating airborne infectious isolation containment using fluorescent microspheres
    David L Johnson
    Department of Occupational and Environmental Health, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma 73126 0901, USA
    J Occup Environ Hyg 5:271-7. 2008
    ..This technique can be employed using generally available equipment and inexpensive supplies and also can minimize the number of particle counts that must be performed. The method is shown to be specific, sensitive, and accurate...
  57. ncbi Space Station Biological Research Project (SSBRP) Cell Culture Unit (CCU) and incubator for International Space Station (ISS) cell culture experiments
    Donald Vandendriesche
    NASA Ames Research Center, Moffett Field, CA 94035, USA
    J Gravit Physiol 11:93-103. 2004
    ..The Incubator provides a 4-45 degrees C controlled environment for life science experiments or storage of experimental reagents...
  58. ncbi Probing and overcoming a mould menace
    William Roth
    Jacques Whitford Environment Limited
    Health Estate 56:50-1. 2002
    ..Bruce Fraser is the corporate technical director of indoor air quality for JWEL and regularly provides technical assistance for mould related projects carried out by JWEL...
  59. ncbi Continuous microbiological air monitoring for aseptic filling lines
    Claudia Scherwing
    Sartorius AG, Weender Landstr Göttingen, Germany
    PDA J Pharm Sci Technol 61:102-9. 2007
    ..Aseptic filling is the production cycle with one of the highest contamination risks. A typical method of contamination monitoring is to actively draw air and filter it through special gelatin filters...
  60. ncbi A simple method for tracer containment testing of hospital isolation rooms
    James P Rydock
    Norwegian Building Research Institute, Oslo
    Appl Occup Environ Hyg 17:486-90. 2002
    ..Possible practical applications of the method are discussed...
  61. ncbi Ground based ISS payload microgravity disturbance assessments
    Anne M McNelis
    NASA Glenn Research Center, Cleveland Ohio 44135, USA
    Acta Astronaut 57:205-14. 2005
    ..The major topics to be addressed in this paper are: (1) Microgravity Requirements, (2) Microgravity Disturbers, (3) MEL Testing, (4) Disturbance Control, (5) Microgravity Control Process, and (6) On-Orbit Predictions and Verification...
  62. ncbi Indoor air concerns
    Cindy Baldwin
    Terracon Consultants, Inc, Cedar Rapids, Iowa, USA
    Occup Health Saf 75:26, 29-30, 32. 2006
  63. ncbi Environmental infection control of tuberculosis
    Edward A Nardell
    Harvard School of Medicine, School of Public Health, and the Program in Infectious Disease and Social Change, Department of Social Medicine, Harvard Medical School, Boston, MA, USA
    Semin Respir Infect 18:307-19. 2003
    ..Improved air disinfection through general ventilation, filtration, and ultraviolet germicidal irradiation are needed as ways to address this overlooked source of transmission...
  64. ncbi Guidelines for environmental infection control in health-care facilities. Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee (HICPAC)
    Lynne Sehulster
    Division of Healthcare Quality Promotion, National Center for Infectious Diseases
    MMWR Recomm Rep 52:1-42. 2003
    ..The report also suggests a series of performance measurements as a means to evaluate infection-control efforts...
  65. ncbi The effect of reducing levels of cat allergen (Fel d 1) on clinical symptoms in patients with cat allergy
    Unnur Steina Bjornsdottir
    Health Care Center, Reykjavik, Iceland
    Ann Allergy Asthma Immunol 91:189-94. 2003
    ..Treatment of cat allergy normally entails removal of the cat from the household, but cat owners are often unwilling to part with their pets, despite clinically relevant allergies...
  66. ncbi Trace gases generated in closed plant cultivation systems and their effects on plant growth
    A Tani
    Osaka Prefecture University, Sakai
    Biol Sci Space 9:314-26. 1995
    ..from plants, ethylene concentration in a closed chamber in which the plants were cultivated under a controlled environment (25 degrees C air temperature, 60-70% relative humidity, 250-300 micromoles m-2 s-1 photosynthetic photon ..
  67. ncbi Contribution of the scrotum, testes, and testicular artery to scrotal/testicular thermoregulation in bulls at two ambient temperatures
    J P Kastelic
    Research Centre, Agriculture and Agri Food Canada, Lethbridge, Alta, Canada
    Anim Reprod Sci 45:255-61. 1997
    ..Crossbred beef bulls, 1.5 years of age, were placed in controlled environment chambers at ambient temperatures of 15 degrees C (n = 5) or 25 degrees C (n = 6)...
  68. pmc Short-term genome evolution of Listeria monocytogenes in a non-controlled environment
    Renato H Orsi
    Department of Food Science, Cornell University, Ithaca, NY, USA
    BMC Genomics 9:539. 2008
    ..While a genome sequence for the 1988 food isolate has been reported, we sequenced the genomes of the 1988 human isolate as well as a human and a food isolate from the 2000 outbreak to allow for comparative genome analyses...
  69. pmc The effect of hydrogen bonding on the diffusion of water in n-alkanes and n-alcohols measured with a novel single microdroplet method
    Jonathan T Su
    Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708 0300, USA
    J Chem Phys 132:044506. 2010
    ..technique, which can form and hold a single microdroplet of water while it dissolves in a diffusion controlled environment into the solvent...
  70. ncbi Elevated carbon dioxide increases contents of flavonoids and phenolic compounds, and antioxidant activities in Malaysian young ginger (Zingiber officinale Roscoe.) varieties
    Ali Ghasemzadeh
    Department of Crop Science, Faculty of Agriculture, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
    Molecules 15:7907-22. 2010
    ..parts of Malaysian young ginger varieties (Halia Bentong and Halia Bara) with CO(2) enrichment in a controlled environment system...
  71. doi A prospective comparison of bilateral photoplethysmography versus the ankle-brachial pressure index for detecting and quantifying lower limb peripheral arterial disease
    John Allen
    Regional Medical Physics Department, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    J Vasc Surg 47:794-802. 2008
    ..This study prospectively assessed the diagnostic accuracy of a novel bilateral photoplethysmography toe pulse measurement technique for the detection of significant lower limb peripheral arterial disease...
  72. pmc Organic acid production in vitro and plant growth promotion in maize under controlled environment by phosphate-solubilizing fluorescent Pseudomonas
    Pratibha Vyas
    Plant Pathology and Microbiology Laboratory, Institute of Himalayan Bioresource Technology CSIR, Palampur HP 176 061, India
    BMC Microbiol 9:174. 2009
    ..This paper describes the production of organic acids during inorganic phosphate solubilization and influence on plant growth as a function of phosphate solubilization by fluorescent Pseudomonas...
  73. ncbi Application of high-Cu compost to dill and peppermint
    Valtcho D Zheljazkov
    Department of Plant and Animal Sciences, Nova Scotia Agricultural College, P O Box 550, Truro, NS, B2N 5E3, Canada
    J Agric Food Chem 52:2615-22. 2004
    A controlled environment experiment was conducted to determine the effect of amending soil with various rates of high-Cu compost (0, 20, 40, and 60% compost/soil by volume) on dill (Anethum graveolens L...
  74. ncbi Biological control in greenhouse systems
    T C Paulitz
    USDA ARS Root Disease and Biocontrol Research Unit, 363 Johnson Hall, Washington State University, Pullman, Washington 99164 6430, USA
    Annu Rev Phytopathol 39:103-33. 2001
    The controlled environment of greenhouses, the high value of the crops, and the limited number of registered fungicides offer a unique niche for the biological control of plant diseases...
  75. ncbi Influence of controlled lactic fermentation on growth and sporulation of Bacillus cereus in milk
    Elisabeth Røssland
    Department of Chemistry, Biotechnology and Food Science, Agricultural University of Norway, P O Box 5003, N 1432 As, Norway
    Int J Food Microbiol 103:69-77. 2005
    ..cereus in a controlled environment during the initial part of fermentation and to observe if other factors than lactic acid influenced the ..
  76. ncbi Influence of nitrogen nutrition management on biomass partitioning and nitrogen use efficiency indices in hydroponically grown potato
    Gregory D Goins
    Dynamac Corporation, Kennedy Space Center, FL 32899, USA
    J Am Soc Hortic Sci 129:134-40. 2004
    The National Aeronautics and Space Administration (NASA) has been conducting controlled environment research with potatoes (Solanum tuberosum L...
  77. doi Climate sensitivity of gaseous elemental mercury dry deposition to plants: impacts of temperature, light intensity, and plant species
    Andrew P Rutter
    Environmental Chemistry and Technology Program, Madison, Wisconsin 53705, United States
    Environ Sci Technol 45:569-75. 2011
    ..of 10 and 30 °C and nominal irradiances of 0, 80, and 170 W m(-2) (300 nm-700 nm) in a 19 m(3) controlled environment chamber...
  78. pmc Early-life stress disrupts attachment learning: the role of amygdala corticosterone, locus ceruleus corticotropin releasing hormone, and olfactory bulb norepinephrine
    Stephanie Moriceau
    Emotional Brain Institute, Nathan Kline Institute, Orangeburg, New York 10962, USA
    J Neurosci 29:15745-55. 2009
    ..We also assessed the neural mechanism for stressed-reared pups' abnormal behavior in a more controlled environment by injecting normally reared pups with CORT...
  79. pmc Effect of ovalbumin aerosol exposure on colonization of the porcine upper airway by Pasteurella multocida and effect of colonization on subsequent immune function
    T D Hamilton
    Department of Clinical Veterinary Sciences, School of Veterinary Sciences, University of Bristol, Langford, England
    Clin Diagn Lab Immunol 5:494-8. 1998
    ..to 10 groups (A to J), accommodated in stainless steel exposure chambers, and exposed continuously to a controlled environment containing aerosolized ovalbumin...
  80. ncbi Effects of L-arginine-enriched total enteral nutrition on body weight gain, tumor growth, and in vivo concentrations of blood and tissue metabolites in rats inoculated with Walker tumor in the kidney
    Lúcio Flávio Gonzaga Silva
    Department of Surgery, Federal University of Ceara, CEP 60 430 140, Rodolfo Teofilo, Fortaleza, Ceara, Brazil
    Nutrition 20:225-9. 2004
    ....
  81. doi Trial design to estimate the effect of vaccination on tuberculosis incidence in badgers
    Inma Aznar
    CVERA, Centre for Veterinary Epidemiology and Risk Analysis, Veterinary Science Centre, School of Agriculture Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
    Vet Microbiol 151:104-11. 2011
    ..As the vaccine has been tested in a controlled environment with precise information on infection pressure, it cannot be assumed a priori that the effects of ..
  82. doi Changes in antimicrobial resistance among faecal enterococci isolated from growing broilers prophylactically medicated with three commercial antimicrobials
    Paulo Martins da Costa
    ICBAS, Instituto de Ciencias Biomedicas de Abel Salazar, Universidade do Porto, Largo Professor Abel Salazar, 2, 4099 003 Porto, Portugal
    Prev Vet Med 93:71-6. 2010
    A controlled environment poultry house (1600m(2)) was divided into two separated compartments. Three hundred twenty chick containers (each containing 100 chicks) were randomly allocated to each compartment...
  83. doi Growth, photosynthesis, nitrogen partitioning and responses to CO2 enrichment in a barley mutant lacking NADH-dependent nitrate reductase activity
    Richard C Sicher
    United States Department of Agriculture, Agricultural Research Service, Crop Systems and Global Change Laboratory, Plant Sciences Institute, Beltsville, MD 20705, USA
    Physiol Plant 134:31-40. 2008
    ..In controlled environment experiments, total biomass, rates of photosynthesis, stomatal conductance, intercellular CO(2) ..
  84. ncbi The effects of systemic hypoxia on colon anastomotic healing: an animal model
    Jo Anne P Attard
    GI Research Group, Department of Surgery, University of Calgary, Calgary, Alberta, Canada
    Dis Colon Rectum 48:1460-70. 2005
    ....
  85. ncbi Chitin-supplemented foliar application of chitinolytic Bacillus cereus reduces severity of Botrytis gray mold disease in chickpea under controlled conditions
    G K Kishore
    Department of Pathology, International Crops Research Institute for the Semi Arid Tropics, Patancheru 502 324, India
    Lett Appl Microbiol 44:98-105. 2007
    ..To identify and evaluate chitinolytic bacteria for control of Botrytis gray mold (BGM), a devastating disease in chickpea...
  86. doi Creating the animated intensive care unit
    Jesse B Hall
    Department of Anesthesia and Critical Care, University of Chicago, Chicago, IL, USA
    Crit Care Med 38:S668-75. 2010
    ..The management of critically ill patients has increasingly involved creation of a highly controlled environment by care providers, with patients immobilized, tethered to devices, and receiving multiple drugs to ..
  87. doi Effect of pistachio diet on lipid parameters, endothelial function, inflammation, and oxidative status: a prospective study
    Ibrahim Sari
    Cardiology Department, Gaziantep University, School of Medicine, Gaziantep, Turkey
    Nutrition 26:399-404. 2010
    ..We aimed to investigate effect of the Antep pistachio (Pistacia vera L.) on blood glucose, lipid parameters, endothelial function, inflammation, and oxidation in healthy young men living in a controlled environment.
  88. doi Uptake and transformation of soil [14C]-trinitrotoluene by cool-season grasses
    Jennifer M Duringer
    Department of Environmental and Molecular Toxicology, Oregon State University, 139 Oak Creek Building, Corvallis, Oregon 97331, USA
    Environ Sci Technol 44:6325-30. 2010
    ..ryegrass (Lolium perenne), and tall fescue (Festuca arundinacea) over a one year period in a greenhouse-controlled environment. Pots (n = 4 for each grass, containing 10 mg cold TNT/kg soil + 1...
  89. pmc Water-use responses of 'living fossil' conifers to CO2 enrichment in a simulated Cretaceous polar environment
    Laura Llorens
    Department of Animal and Plant Sciences, University of Sheffield, Sheffield, UK
    Ann Bot 104:179-88. 2009
    ....
  90. ncbi Lack of relationship between either specific weight or presence of the 1B1R gene and nutritive value of wheat in broiler diets
    K J McCracken
    Agricultural and Environmental Science Division, Department of Agriculture and Rural Development now Agri Food Biosciences Institute, Newforge Lane, Belfast
    Br Poult Sci 49:463-74. 2008
    ..They were fed ad libitum to male, Ross broiler chicks from 7 to 28 d, in individual cages in a controlled environment room. 4...
  91. ncbi Aquaculture of three phyla of marine invertebrates to yield bioactive metabolites: process developments and economics
    Dominick Mendola
    CalBioMarine Technologies, Inc, 1001 Capri Road, Encinitas, CA 92024, USA
    Biomol Eng 20:441-58. 2003
    ..for its anti-parasitic and anti-infective kalihinols) in-sea systems were not developed in favor of controlled environment tank aquaculture systems...
  92. pmc Non-invasive monitoring of chewing and swallowing for objective quantification of ingestive behavior
    Edward Sazonov
    Department of Electrical and Computer Engineering, Clarkson University, Potsdam, NY 13699, USA
    Physiol Meas 29:525-41. 2008
    ..sensors, related hardware and software for multi-modal data capture is designed for data collection in a controlled environment. Second, a protocol is developed for manual scoring of chewing and swallowing for use as a gold standard...
  93. ncbi Improvement of COD and color removal from UASB treated poultry manure wastewater using Fenton's oxidation
    Kaan Yetilmezsoy
    Department of Environmental Engineering, Yildiz Technical University, 34349 Yildiz, Besiktas, Istanbul, Turkey
    J Hazard Mater 151:547-58. 2008
    ..The UASB reactor was operated for 72 days at mesophilic conditions (32+/-2 degrees C) in a temperature-controlled environment with three different hydraulic retention times (HRT) of 15.7, 12 and 8...
  94. doi Effects of antimicrobial treatment on selection of resistant Escherichia coli in broiler fecal flora
    Paulo Martins da Costa
    ICBAS Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Porto, Portugal
    Microb Drug Resist 14:299-306. 2008
    ..A control group of 16,000 broilers was placed in the same controlled environment poultry house. Feed diet and fecal samples from both groups were collected periodically...
  95. ncbi Establishment and characterization of an immortomouse-derived odontoblast-like cell line to evaluate the effect of insulin-like growth factors on odontoblast differentiation
    Javier Caton
    Center for Craniofacial Molecular Biology, University of Southern California School of Dentistry, Los Angeles, California 90033, USA
    J Cell Biochem 100:450-63. 2007
    ..to determine the effect of IGF on odontoblast cell differentiation we first need a cell line in which a controlled environment can be created...
  96. ncbi Different nocturnal body temperatures and sleep with forced-air warming in men and in women taking hormonal contraceptives
    F C Baker
    Department of Physiology, University of the Witwatersrand Medical School, South Africa
    J Sleep Res 7:175-81. 1998
    ..healthy women who were taking oral or injection contraceptives, and six healthy men spent 3 nights in a controlled environment: an adaptation night followed by 2 nights when they slept under either a down duvet (baseline) or a quilt ..
  97. ncbi Temperature effects on wood anatomy, wood density, photosynthesis and biomass partitioning of Eucalyptus grandis seedlings
    D S Thomas
    Centre for Horticulture and Plant Sciences, University of Western Sydney, Locked Bag 1797 South Penrith, NSW 1797, Australia
    Tree Physiol 27:251-60. 2007
    ..Increased Ac increased seedling volume, biomass and wood density; but increased wood density was also related to a shift in partitioning of seedling biomass from roots to stems as temperature increased...
  98. doi The utility of endovascular simulation to improve technical performance and stimulate continued interest of preclinical medical students in vascular surgery
    Jason T Lee
    Division of Vascular Surgery, Stanford University School of Medicine, Stanford, California 94305, USA
    J Surg Educ 66:367-73. 2009
    ..Surgical simulation has emerged as an educational tool for trainees to practice procedures in a controlled environment allowing interested medical students to perform procedures without compromising patient safety...
  99. ncbi Experimental infection of house finches with Mycoplasma gallisepticum
    George V Kollias
    Wildlife Health Laboratory, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853 6401, USA
    J Wildl Dis 40:79-86. 2004
    ..individually housed house finches that were experimentally inoculated with the finch strain of MG in a controlled environment. To accomplish this, a study was conducted spanning the period of November 2001-April 2002 with 20 MG-free ..
  100. doi Development of ramulosis disease of cotton under controlled environment and field conditions
    José Eduardo B A Monteiro
    Agrometeorology Group, Department of Exact Sciences, ESALQ, University of Sao Paulo, P O Box 9, 13418 900 Piracicaba, SP, Brazil
    Phytopathology 99:659-65. 2009
    ..Latent period, incidence, and severity of ramulosis symptoms were evaluated in controlled environment experiments using factorial combinations of temperature (15, 20, 25, 30, and 35 degrees C) and leaf ..
  101. ncbi [Blood glucose and ketone monitoring in type 1 diabetic patients in the controlled environment of a summer camp]
    J P López Siguero
    Endocrinologia Pediatrica, Hospital Materno Infantil de Málaga, Espana
    An Pediatr (Barc) 66:387-92. 2007
    ....

Research Grants77

  1. A randomized trial of bariatric surgery for the treatment of sleep apnea
    Sanjay R Patel; Fiscal Year: 2010
    ..e., in the OSA arm, while using CPAP in a controlled environment vs...
  2. Plant-Derived hepatitis B Vaccine from Biomanufacturing System to Clinical Trial
    Robert Britt; Fiscal Year: 2009
    ..Plant-derived hepatitis B vaccine from potatoes grown in controlled environment biomanufacturing facilities will provide for orally administered vaccines that can be manufactured as ..
  3. Adjustable balloon implant for medialization thyroplasty
    Matthew R Hoffman; Fiscal Year: 2012
    ..Experiments will be conducted using the excised larynx bench apparatus which offers a controlled environment with repeatable conditions and immediately available information on treatment efficacy...
  4. Reflex Contributions to Joint Stability
    YASIN DHAHER; Fiscal Year: 2004
    ..joint and seek to characterize the input-output properties of joint afferents-based reflexes in a well-controlled environment. The choice of knee varus/valgus (v/v) as a model is advantageous because there is less likelihood that ..
  5. Reflex Contributions to Joint Stability
    YASIN DHAHER; Fiscal Year: 2005
    ..joint and seek to characterize the input-output properties of joint afferents-based reflexes in a well-controlled environment. The choice of knee varus/valgus (v/v) as a model is advantageous because there is less likelihood that ..
  6. Reflex Contributions to Joint Stability
    YASIN DHAHER; Fiscal Year: 2007
    ..joint and seek to characterize the input-output properties of joint afferents-based reflexes in a well-controlled environment. The choice of knee varus/valgus (v/v) as a model is advantageous because there is less likelihood that ..
  7. Reflex Contributions to Joint Stability
    YASIN DHAHER; Fiscal Year: 2006
    ..joint and seek to characterize the input-output properties of joint afferents-based reflexes in a well-controlled environment. The choice of knee varus/valgus (v/v) as a model is advantageous because there is less likelihood that ..
  8. NEURAL CONTROL OF THE GALLBLADDER
    Gary M Mawe; Fiscal Year: 2010
    ..This approach allows us to examine the actions of these compounds individually on GBSM in a controlled environment. This grant proposal involves an integrated approach using state-of-the-art techniques to investigate ..
  9. NEURAL CONTROL OF THE GALLBLADDER
    Gary Mawe; Fiscal Year: 2009
    ..This approach allows us to examine the actions of these compounds individually on GBSM in a controlled environment. This grant proposal involves an integrated approach using state-of-the-art techniques to investigate ..
  10. CHEMORECEPTOR ACTIVITY OF THE CAROTID BODY
    Carlos Eyzaguirre; Fiscal Year: 1990
    ..3) Trophic interactions between glomus cells and sensory fibers will be continued in a controlled environment by using cultured sensory ganglion neurons grown alone and with glomus cells since the neuronal electric ..
  11. Interactions Between the Brain Reward and Pain Systems.
    Conan Kornetsky; Fiscal Year: 2010
    ..question, does pain change the sensitivity of a brain reward site? Out-patients in pain, who are not in a controlled environment and are using prescription opiates, may be a greater risk for addiction than the person without pain ..
  12. Interactions Between the Brain Reward and Pain Systems.
    Conan Kornetsky; Fiscal Year: 2009
    ..question, does pain change the sensitivity of a brain reward site? Out-patients in pain, who are not in a controlled environment and are using prescription opiates, may be a greater risk for addiction than the person without pain ..
  13. A Novel Approach to Assessing Cognitive State During Real-World Tasks
    Robin Johnson; Fiscal Year: 2011
    ..who will, or will not, succeed at real-world tasks, since most assessments rely on testing from in a controlled environment (clinic, laboratory) to predict performance in the less controlled and more chaotic real world...
  14. Using light to increase visual and perceptual cues and decrease falls risk
    MARIANA FIGUEIRO; Fiscal Year: 2009
    ..of this lighting solution in reducing fall risk among older adults living at home and in a more controlled environment. The lighting solution proposed here should enable older adults to get out of bed at night more quickly ..
  15. Using light to increase visual and perceptual cues and decrease falls risk
    MARIANA FIGUEIRO; Fiscal Year: 2010
    ..of this lighting solution in reducing fall risk among older adults living at home and in a more controlled environment. The lighting solution proposed here should enable older adults to get out of bed at night more quickly ..
  16. 23Na MRI: Ordered Sodium as a Reporter of Cartilage Degradation
    Alexej Jerschow; Fiscal Year: 2007
    ..In order to study the behavior of the associated sodium pool in the most controlled environment, it is planned to measure the Na NMR parameters in (i) proteoglycan/collagen/agarose mixtures, (ii) 23 in ..
  17. "Mucins of the Ocular Surface"
    Ilene Gipson; Fiscal Year: 2009
    ..protecting the eye from fluid loss and dry eye, using mice null for membrane associated mucins housed in a controlled environment chamber which reliably produces decreased tear volume in mice...
  18. "Mucins of the Ocular Surface"
    Ilene K Gipson; Fiscal Year: 2010
    ..protecting the eye from fluid loss and dry eye, using mice null for membrane associated mucins housed in a controlled environment chamber which reliably produces decreased tear volume in mice...
  19. A lateral flow CD4 counting assay for resource-poor regions
    Michael Lane; Fiscal Year: 2007
    ..to use relatively complex equipment (cytometers, cell sorters, plate readers) and such equipment needs a controlled environment (machine maintenance in high humidity and non-standard temperature environments is problematic)...
  20. "Mucins of the Ocular Surface"
    Ilene Gipson; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  21. "Mucins of the Ocular Surface"
    Ilene Gipson; Fiscal Year: 2009
    ..protecting the eye from fluid loss and dry eye, using mice null for membrane associated mucins housed in a controlled environment chamber which reliably produces decreased tear volume in mice...
  22. MUCINS OF THE OCULAR SURFACE
    Ilene Gipson; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  23. Sex, sex steroids and dry eye syndromes
    David Sullivan; Fiscal Year: 2006
    ..enzyme assays, histology, image analysis, hormone reconstitution experiments, as well as use of a controlled environment chamber...
  24. Sleep Therapy Headset for Improving Sleep Quality of Older Adults
    PHILIP BONELLO; Fiscal Year: 2007
    ..This can potentially delay transition to more controlled environment and reduce falls among older adults...
  25. Sex, sex steroids and dry eye syndromes
    David Sullivan; Fiscal Year: 2009
    ..enzyme assays, histology, image analysis, hormone reconstitution experiments, as well as use of a controlled environment chamber...
  26. Sex, sex steroids and dry eye syndromes
    David Sullivan; Fiscal Year: 2007
    ..enzyme assays, histology, image analysis, hormone reconstitution experiments, as well as use of a controlled environment chamber...
  27. Sex, sex steroids and dry eye syndromes
    David A Sullivan; Fiscal Year: 2010
    ..enzyme assays, histology, image analysis, hormone reconstitution experiments, as well as use of a controlled environment chamber...
  28. Preparing Long-Term Care Facilities for Natural and Man-Made Disasters
    Susan Harrington; Fiscal Year: 2009
    ..graphics, animation, sound, and high-resolution video to create a fully-interactive media-rich, learner-controlled environment. The program will be evaluated in a national field test with small, medium, and large long-term care ..
  29. Preparing Long-Term Care Facilities for Natural and Man-Made Disasters
    Susan Harrington; Fiscal Year: 2007
    ..graphics, animation, sound, and high-resolution video to create a fully-interactive media-rich, learner-controlled environment. The program will provide branching to allow learners to access information related to specific types of ..
  30. IN VITRO MODEL FOR PULMONARY EMPHYSEMA
    JUDITH FOSTER; Fiscal Year: 1990
    ..Attempts to investigate specific cell responses to elastin injury within a controlled environment are very difficult with whole tissue studies...
  31. Mouse Models for Interstitial Cystitis
    Edward Schwarz; Fiscal Year: 2004
    ..since pathophysiologic mechanisms can be dissected and therapeutic strategies developed in a far more controlled environment than the clinic...
  32. Mouse Models for Interstitial Cystitis
    Edward Schwarz; Fiscal Year: 2001
    ..since pathophysiologic mechanisms can be dissected and therapeutic strategies developed in a far more controlled environment than the clinic...
  33. Mouse Models for Interstitial Cystitis
    Edward Schwarz; Fiscal Year: 2003
    ..since pathophysiologic mechanisms can be dissected and therapeutic strategies developed in a far more controlled environment than the clinic...
  34. Mouse Models for Interstitial Cystitis
    Edward Schwarz; Fiscal Year: 2002
    ..since pathophysiologic mechanisms can be dissected and therapeutic strategies developed in a far more controlled environment than the clinic...
  35. Exploring the interrelationships of mineral metabolism pathways in kidney disease
    Jason Stubbs; Fiscal Year: 2010
    ..In this model, mineral metabolism pathways can be altered in a controlled environment to gain insight into the interrelationships and tissue specific effects of individual mineral metabolism ..
  36. AXON-TARGETED MICRODEVICES FOR CNS AXON TRANSPORT STUDIES
    SHELLY ELESE SAKIYAMA ELBERT; Fiscal Year: 2010
    ..agents selectively to axons and allow their effects on axonal transport and growth to be examined in a controlled environment. By understanding the effects of toxins or drugs on axon growth and transport, we will gain mechanistic ..
  37. MECHANISMS UNDERLYING CARDIOVASCULAR RISKS IN DIABETES
    Gordon Williams; Fiscal Year: 2000
    ..To accomplish these goals, the investigator proposes to study normal subjects and patients with DM in the controlled environment of a General Clinical Research Center. Pressor and renal hemodynamic responses will be determined...
  38. Quantifying the impact of diet on carcinogen exposure
    JAMES FELTON; Fiscal Year: 2001
    ..3) determine the effects of single and multiple food interactions on carcinogen bioavailability in a controlled environment and 4) determine the biologically effective dose of these compounds in humans and validate the in vitro ..
  39. Quantifying the impact of diet on carcinogen exposure
    JAMES FELTON; Fiscal Year: 2002
    ..3) determine the effects of single and multiple food interactions on carcinogen bioavailability in a controlled environment and 4) determine the biologically effective dose of these compounds in humans and validate the in vitro ..
  40. Quantifying the impact of diet on carcinogen exposure
    JAMES FELTON; Fiscal Year: 2003
    ..3) determine the effects of single and multiple food interactions on carcinogen bioavailability in a controlled environment and 4) determine the biologically effective dose of these compounds in humans and validate the in vitro ..
  41. MECHANISMS UNDERLYING CARDIOVASCULAR RISKS IN DIABETES
    Gordon Williams; Fiscal Year: 1999
    ..To accomplish these goals, the investigator proposes to study normal subjects and patients with DM in the controlled environment of a General Clinical Research Center. Pressor and renal hemodynamic responses will be determined...
  42. Stabilize Addiction/Affect, Begin Inmates' Interferon for HCV of Liver (STAABIHL)
    Peter Friedmann; Fiscal Year: 2007
    ..For HCV-infected inmates, prison provides a controlled environment in which to stabilize substance use and mental health, and assess tolerability of and response to peglFN/..
  43. Stabilize Addiction/Affect, Begin Inmates' Interferon for HCV of Liver (STAABIHL)
    Peter Friedmann; Fiscal Year: 2009
    ..For HCV-infected inmates, prison provides a controlled environment in which to stabilize substance use and mental health, and assess tolerability of and response to peglFN/..
  44. Sex dependent astrocyte activation and alcohol-induced neurotoxicity
    KRISTINE WIREN; Fiscal Year: 2009
    ..female astrocyte populations in a controlled environment. This aim also characterizes astrocyte proliferation, apoptosis, glutamate uptake and release, GABAergic ..
  45. GENERAL CLINICAL RESEARCH CENTER
    Karen Antman; Fiscal Year: 2006
    ..The facility providesinvestigators with the foUowing: 1)the abilityto conduct pharmacokinetic studies in a controlled environment in both adult andpediatric inpatients and outpatients; 2) the resources for timed collection of specimens ..
  46. Sex dependent astrocyte activation and alcohol-induced neurotoxicity
    Kristine M Wiren; Fiscal Year: 2010
    ..female astrocyte populations in a controlled environment. This aim also characterizes astrocyte proliferation, apoptosis, glutamate uptake and release, GABAergic ..
  47. GENERAL CLINICAL RESEARCH CENTER
    ARAM CHOBANIAN; Fiscal Year: 2000
    ..The facility provides investigators with: 1) the ability to conduct pharmacokinetic studies in a controlled environment in both adult and pediatric subjects; 2) the resources for timed collections of specimens and repetitive ..
  48. GENERAL CLINICAL RESEARCH CENTER
    ARAM CHOBANIAN; Fiscal Year: 1999
    ..The facility provides investigators with: 1) the ability to conduct pharmacokinetic studies in a controlled environment in both adult and pediatric subjects; 2) the resources for timed collections of specimens and repetitive ..
  49. GENERAL CLINICAL RESEARCH CENTER
    ARAM CHOBANIAN; Fiscal Year: 2001
    ..The facility provides investigators with: 1) the ability to conduct pharmacokinetic studies in a controlled environment in both adult and pediatric subjects; 2) the resources for timed collections of specimens and repetitive ..
  50. Neural Models of Behavior
    Dana H Ballard; Fiscal Year: 2010
    ..The proposed research uses driving in virtual reality as a controlled environment within which we can ask when and where fixations are made and what influences these choices...
  51. Neural Models of Behavior
    Dana Ballard; Fiscal Year: 2009
    ..The proposed research uses driving in virtual reality as a controlled environment within which we can ask when and where fixations are made and what influences these choices...
  52. High-resolution diffusion tensor imaging in mouse models relevant to autism
    Harish Poptani; Fiscal Year: 2009
    ..excellent model to probe the relationship between brain structure and social/behavioral patterns in a well controlled environment and provides tissue for histological confirmation...
  53. An Imaging-based Disease Model for Understanding Bone Health
    Hooshang Kangarloo; Fiscal Year: 2009
    ..Evaluation will be twofold: 1) technical evaluation of the research in a controlled environment;and 2) clinical evaluation to test the efficacy of the causal disease model and end user interfaces...
  54. High-resolution diffusion tensor imaging in mouse models relevant to autism
    Harish Poptani; Fiscal Year: 2010
    ..excellent model to probe the relationship between brain structure and social/behavioral patterns in a well controlled environment and provides tissue for histological confirmation...
  55. EFFECTS OF AGING AND EXERCISE ON BONE MASS
    Coralease Ruff; Fiscal Year: 1990
    ..of humans, will be used as a model to study the effects of increased physical exercise on bone mass in a controlled environment. 24 female Beagles in a laboratory colony ranging in age from 8 to 13 years, equivalent to humans in the ..
  56. Deltavision RT Image Restoration System for Established Research Core Facility
    Thomas Keller; Fiscal Year: 2007
    ..S/N) than we can achieve currently with low level fluorescence samples provided by our clients; a controlled environment chamber; an improved extremely accurate XYZ stage with auto-focus to maintain focus within each z-stack (..
  57. Generation of therapeutic T cells from cord blood-derived stem cells
    Krishnendu Roy; Fiscal Year: 2009
    ..to efficient generation and expansion of therapeutic T cells from multipotent stem cells in a synthetic, controlled environment could provide a renewable, on-demand and readily available cell source for a variety of disease ..
  58. Interferometric Studies of the Fluid Dynamics of the Tear Film
    PETER KING SMITH; Fiscal Year: 2009
    ..A "controlled environment goggle" will be constructed to control humidity and air flow rate over the cornea...
  59. Image Guided Constitutive Modeling of the Brain Tissue
    Oskar Skrinjar; Fiscal Year: 2003
    ..pilot research is to develop and test the concepts of the Image Guided Constitutive Modeling in the controlled environment: on the brain phantoms with implanted "tumors", with the best possible simulation of the in-vivo brain ..
  60. Image Guided Constitutive Modeling of the Brain Tissue
    Oskar Skrinjar; Fiscal Year: 2004
    ..pilot research is to develop and test the concepts of the Image Guided Constitutive Modeling in the controlled environment: on the brain phantoms with implanted "tumors", with the best possible simulation of the in-vivo brain ..
  61. GLYCOSPHINGOLIPIDS DURING MYOGENESIS IN VITRO
    KENNETH LESKAWA; Fiscal Year: 1990
    ..Despite experimental advantages (a well-defined process in a controlled environment) and decades of research, little is known of the molecular events at the cell surface which lead to or ..
  62. UNIVERSITY OF PENNSYLVANIA SMELL & TASTE CENTER
    RICHARD DOTY; Fiscal Year: 1990
    ..The new Core Facility of the Center, in which the Center's controlled environment room and human air-dilution olfactometer are located, serves as the primary location for the Center's ..
  63. An Imaging-based Disease Model for Understanding Bone Health
    Hooshang Kangarloo; Fiscal Year: 2010
    ..Evaluation will be twofold: 1) technical evaluation of the research in a controlled environment;and 2) clinical evaluation to test the efficacy of the causal disease model and end user interfaces...
  64. GENERAL CLINICAL RESEARCH CENTER
    Karen Antman; Fiscal Year: 2007
    ..The facility provides[unreadable] investigators with the following: 1) the ability to conduct studies in a controlled environment in both adult and[unreadable] pediatric inpatients and outpatients; 2) the resources for collection of ..
  65. ENDOGENOUS REGULATION OF INTRAOCULAR PRESSURE
    John Liu; Fiscal Year: 2000
    ..Under a strictly controlled environment, the circadian IOP pattern in young healthy adults will be critically examined (Aim 3)...
  66. ENDOGENOUS REGULATION OF INTRAOCULAR PRESSURE
    John Liu; Fiscal Year: 2001
    ..Under a strictly controlled environment, the circadian IOP pattern in young healthy adults will be critically examined (Aim 3)...
  67. ENDOGENOUS REGULATION OF INTRAOCULAR PRESSURE
    John Liu; Fiscal Year: 2002
    ..Under a strictly controlled environment, the circadian IOP pattern in young healthy adults will be critically examined (Aim 3)...
  68. ENDOGENOUS REGULATION OF INTRAOCULAR PRESSURE
    John Liu; Fiscal Year: 1999
    ..Under a strictly controlled environment, the circadian IOP pattern in young healthy adults will be critically examined (Aim 3)...
  69. Animal Resources and Pathology Core
    James Fox; Fiscal Year: 2004
    ..These animal facilities provide MIT investigators a controlled environment with the necessary space, equipment, and containment facilities for performing biomedical related research ..