- Ecological responses to recent climate change
Gian Reto Walther
Institute of Geobotany, University of Hannover, Nienburger Str 17, 30167 Hannover, Germany
Nature 416:389-95. 2002
..Although we are only at an early stage in the projected trends of global warming, ecological responses to recent climate change are already clearly visible...
- The reorienting system of the human brain: from environment to theory of mind
Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
Neuron 58:306-24. 2008
- Climate change, human impacts, and the resilience of coral reefs
T P Hughes
Centre for Coral Reef Biodiversity, James Cook University, Townsville, Qld 4811, Australia
Science 301:929-33. 2003
..International integration of management strategies that support reef resilience need to be vigorously implemented, and complemented by strong policy decisions to reduce the rate of global warming...
- Hepatocellular carcinoma pathogenesis: from genes to environment
Paraskevi A Farazi
Department of Genetics, Division of Medical Sciences, Harvard University, Boston, Massachusetts 02115, USA
Nat Rev Cancer 6:674-87. 2006
- Biodiversity and ecosystem functioning: current knowledge and future challenges
Laboratoire d Ecologie, UMR 7625, Ecole Normale Superieure, 46 rue d Ulm, F 75230 Paris cedex 05, France
Science 294:804-8. 2001
..A major future challenge is to determine how biodiversity dynamics, ecosystem processes, and abiotic factors interact...
- Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions
Lance W Hahn
Program in Human Genetics and Department of Molecular Physiology and Biophysics, Vanderbilt University Medical School, Nashville, TN 37232 0700, USA
Bioinformatics 19:376-82. 2003
..be dependent on other genetic variations (gene-gene interaction or epistasis) and environmental factors (gene-environment interaction)...
- Epigenetics and the environment: emerging patterns and implications
Institute of Molecular Genetics IGMM, CNRS UMR 5535 and University of Montpellier, 1919 Route de Mende, 34293 Montpellier, France cnrs fr
Nat Rev Genet 13:97-109. 2011
..These have implications for structuring future research and understanding disease and development...
- Genomic expression programs in the response of yeast cells to environmental changes
A P Gasch
Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305 5428, USA
Mol Biol Cell 11:4241-57. 2000
..Physiological themes in the genomic responses to specific environmental stresses provided insights into the effects of those stresses on the cell...
- Phenotypic diversity, population growth, and information in fluctuating environments
Laboratory of Living Matter and Center for Studies in Physics and Biology, Rockefeller University, 1230 York Avenue, Box 34, New York, NY 10021 6399, USA
Science 309:2075-8. 2005
..Here we show that stochastic switching can be favored over sensing when the environment changes infrequently. The optimal switching rates then mimic the statistics of environmental changes...
- Understanding physical activity environmental correlates: increased specificity for ecological models
School of Population Health, The University of Western Australia, Perth, Australia
Exerc Sport Sci Rev 33:175-81. 2005
..This selective review examines whether the predictive capacity of these models could be improved if behavior-specific measures of the environment were used to predict context-specific behaviors.
- Understanding environmental influences on walking; Review and research agenda
Cancer Prevention Research Centre, School of Population Health, University of Queensland, Brisbane, Queensland, Australia
Am J Prev Med 27:67-76. 2004
..Walking is the most common physical activity behavior of adults; environmental innovations may be able to influence rates of participation...
- Adaptation of Drosophila to a novel laboratory environment reveals temporally heterogeneous trajectories of selected alleles
Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria
Mol Ecol 21:4931-41. 2012
..generation sequencing of DNA pools (Pool-Seq) to identify alleles that are favourable in a novel laboratory environment and traced their trajectories during the adaptive process...
- Use of global positioning systems to study physical activity and the environment: a systematic review
Patricia J Krenn
Institute of Sport Science, University of Graz, Austria
Am J Prev Med 41:508-15. 2011
..The aim of this systematic review was to determine the capability of GPS to collect high-quality data on the location of activities in research on the relationship between physical activity and the environment.
- An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus
Chirag J Patel
Department of Pediatrics and Medicine, Stanford University School of Medicine, Stanford, California, USA
PLoS ONE 5:e10746. 2010
..We conducted a pilot Environmental-Wide Association Study (EWAS), in which epidemiological data are comprehensively and systematically interpreted in a manner analogous to a Genome Wide Association Study (GWAS)...
- Green space, urbanity, and health: how strong is the relation?
NIVEL, Netherlands Institute for Health Services Research, PO Box 1568, 3500 BN Utrecht, Netherlands
J Epidemiol Community Health 60:587-92. 2006
To investigate the strength of the relation between the amount of green space in people's living environment and their perceived general health. This relation is analysed for different age and socioeconomic groups...
- Jack of all trades, master of some? On the role of phenotypic plasticity in plant invasions
Christina L Richards
Department of Ecology and Evolution, Stony Brook University, 650 Life Sciences, Stony Brook, NY 11794 5245, USA
Ecol Lett 9:981-93. 2006
..This new framework can be applied when testing both ecological or evolutionary oriented hypotheses, and therefore promises to bridge the gap between the two perspectives...
- Gene-environment interaction in yeast gene expression
Erin N Smith
Lewis Sigler Institute for Integrative Genomics and Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America
PLoS Biol 6:e83. 2008
..genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood...
- Correlates of adults' participation in physical activity: review and update
Stewart G Trost
School of Human Movement Studies, University of Queensland, Brisbane QLD 4072, Australia
Med Sci Sports Exerc 34:1996-2001. 2002
..To review and update the evidence relating to the personal, social, and environmental factors associated with physical activity (PA) in adults...
- Abiotic stress, the field environment and stress combination
Department of Biochemistry and Molecular Biology, University of Nevada, Mail Stop 200, Reno, NV 89557, USA
Trends Plant Sci 11:15-9. 2006
..Tolerance to a combination of different stress conditions, particularly those that mimic the field environment, should be the focus of future research programs aimed at developing transgenic crops and plants with enhanced ..
- Stochastic switching as a survival strategy in fluctuating environments
Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
Nat Genet 40:471-5. 2008
..Each phenotype was designed to confer a growth advantage over the other phenotype in a certain environment. When we compared the growth of two populations with different switching rates, we found that fast-switching ..
- Neighborhood environments and physical activity among adults in 11 countries
James F Sallis
Active Living Research, Department of Psychology, San Diego State University, San Diego, California 92103, USA
Am J Prev Med 36:484-90. 2009
..Surveys were conducted in 11 countries using the same self-report environmental variables and the International Physical Activity Questionnaire, allowing analyses with pooled data...
- Attractor dynamics in the hippocampal representation of the local environment
Tom J Wills
Department of Anatomy and Developmental Biology, University College London, London WC1E 6BT, UK
Science 308:873-6. 2005
..This enables study of attractor dynamics in a cognitive representation and may correspond to the formation of distinct contexts in context-dependent memory...
- C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway
E R Sawin
Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA
Neuron 26:619-31. 2000
..The basal and enhanced slowing responses are distinct and separable neuromodulatory components of a genetically tractable paradigm of behavioral plasticity...
- Confounding factors in the detection of species responses to habitat fragmentation
Robert M Ewers
School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
Biol Rev Camb Philos Soc 81:117-42. 2006
..a landscape-level phenomenon in which species that survive in habitat remnants are confronted with a modified environment of reduced area, increased isolation and novel ecological boundaries...
- Unravelling the effects of the environment and host genotype on the gut microbiome
Department of Microbiology, Cornell University, Ithaca, New York 14853, USA
Nat Rev Microbiol 9:279-90. 2011
..In this Review, we describe how host genetics and the environment shape the microbiota, and how these three factors may interact in the context of chronic disease.
- Potential environmental determinants of physical activity in adults: a systematic review
Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
Obes Rev 8:425-40. 2007
..However, most studies used cross-sectional designs and non-validated measures of environments and/or behaviour. Therefore, no strong conclusions can be drawn and more research of better quality is clearly needed...
- Genetics of mouse behavior: interactions with laboratory environment
J C Crabbe
Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, Portland, OR 97201, USA
Science 284:1670-2. 1999
..Possible confounding influences of the laboratory environment were studied in several inbred strains and one null mutant by simultaneous testing in three laboratories on a ..
- Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation
Department of Genetics, Evolution and Environment, UCL Cancer Institute, University College London, London WC1E 6BT, UK
Nat Rev Genet 9:583-93. 2008
..insight into cellular strategies for keeping gene expression in tune with physiological needs dictated by the environment, promoting adaptation to both short- and long-term environmental changes...
- Adaptation, plasticity, and extinction in a changing environment: towards a predictive theory
Luis Miguel Chevin
Division of Biology, Imperial College London, Silwood Park, United Kingdom
PLoS Biol 8:e1000357. 2010
..The unusual rate and extent of anthropogenic alterations of the environment may exceed the capacity of developmental, genetic, and demographic mechanisms that populations have evolved to ..
- Freshwater biodiversity: importance, threats, status and conservation challenges
Department of Ecology and Biodiversity, The University of Hong Kong, Hong Kong SAR, China
Biol Rev Camb Philos Soc 81:163-82. 2006
..Recognition of this need will require adoption of a new paradigm for biodiversity protection and freshwater ecosystem management - one that has been appropriately termed 'reconciliation ecology'...
- Morbidity is related to a green living environment
EMGO Institute, VU University Medical Centre, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
J Epidemiol Community Health 63:967-73. 2009
..There is increasing evidence for a positive relation between green space in people's living environment and self-reported indicators of physical and mental health...
- Global dispersal of free-living microbial eukaryote species
Bland J Finlay
Centre for Ecology and Hydrology Windermere, Ferry House, Ambleside, Cumbria LA22 0LP, UK
Science 296:1061-3. 2002
- Environmental correlates of physical activity in youth - a review and update
Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands
Obes Rev 8:129-54. 2007
..Low crime incidence (in adolescents) was characteristic of the neighbourhood environment associated with higher PA...
- Forecasting agriculturally driven global environmental change
Department of Ecology, Evolution and Behavior, University of Minnesota, 1987 Upper Buford Circle, St Paul, MN 55108, USA
Science 292:281-4. 2001
..Significant scientific advances and regulatory, technological, and policy changes are needed to control the environmental impacts of agricultural expansion...
- The frontoparietal attention network of the human brain: action, saliency, and a priority map of the environment
Division of Neurorehabilitation, Geneva University Hospital, University of Geneva, Switzerland
Neuroscientist 18:502-15. 2012
..to a central role of this region in the computation of a feature- and modality-independent priority map of the environment. The priority map integrates feature information elaborated in sensory cortex and top-down representations of ..
- The environment and schizophrenia
Jim Van Os
European Graduate School for Neuroscience, SEARCH, Maastricht University Medical Centre, 6200 MD Maastricht, The Netherlands
Nature 468:203-12. 2010
..emphasized, onset is associated with environmental factors such as early life adversity, growing up in an urban environment, minority group position and cannabis use, suggesting that exposure may have an impact on the developing '..
- Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution
Scientific Institute IRCCS E Medea, Bioinformatic Lab, Bosisio Parini, Italy
PLoS Genet 7:e1002355. 2011
..Furthermore, we show that the diversity of the local pathogenic environment is the predominant driver of local adaptation, and that climate, at least as measured here, only plays a ..
- Climate change and evolution: disentangling environmental and genetic responses
Ecological Genetics Research Unit, Department of Biological and Environmental Sciences, PO Box 65, FI 00014 University of Helsinki, Finland
Mol Ecol 17:167-78. 2008
..Hence, clear-cut evidence indicating a significant role for evolutionary adaptation to ongoing climate warming is conspicuously scarce...
- Climate change and distribution shifts in marine fishes
Allison L Perry
Centre for Ecology, Evolution and Conservation, School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK
Science 308:1912-5. 2005
..Further temperature rises are likely to have profound impacts on commercial fisheries through continued shifts in distribution and alterations in community interactions...
- Healthy nutrition environments: concepts and measures
Rollins School of Public Health, Emory University, 1518 Clifton Road, NE, Room 526, Atlanta, GA 30322, USA
Am J Health Promot 19:330-3, ii. 2005
The authors provide a conceptual model of a healthy nutrition environment, then review the types of measures required to assess various aspects of this environment...
- Home environment relationships with children's physical activity, sedentary time, and screen time by socioeconomic status
Pooja S Tandon
Seattle Children s Research Institute, M S CW8 6, P, O, Box 5371, Seattle, WA 98145 5005, USA
Int J Behav Nutr Phys Act 9:88. 2012
..We aimed to determine if home physical activity (PA) environments differed by SES and to explore home environment mediators of the relation of family SES to children's PA and sedentary behavior.
- School and residential neighborhood food environment and diet among California youth
RAND Corporation, Santa Monica, California, USA
Am J Prev Med 42:129-35. 2012
..For youth, empirical evidence for any particular hypothesis remains limited...
- Deletion and acquisition of genomic content during early stage adaptation of Pseudomonas aeruginosa to a human host environment
Martin H Rau
Department of Systems Biology, Technical University of Denmark, 2800 Lyngby, Denmark
Environ Microbiol 14:2200-11. 2012
..Finally, we also describe the complete genome of this highly adapted pathogenic strain of P.aeruginosa to strengthen the genetic basis, which serves to help our understanding of microbial evolution in a natural environment.
- Vulnerability genes or plasticity genes?
Institute for the Study of Children, Families and Social Issues, Birkbeck University of London, London, UK
Mol Psychiatry 14:746-54. 2009
..as particularly vulnerable to adversity, informs virtually all psychiatric research on behavior-gene-environment (G x E) interaction...
- A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry
Laramie E Duncan
Harvard School of Public Health, Massachusetts General Hospital, McLean Hospital, Harvard Medical School, Belmont, USA
Am J Psychiatry 168:1041-9. 2011
Gene-by-environment interaction (G×E) studies in psychiatry have typically been conducted using a candidate G×E (cG×E) approach, analogous to the candidate gene association approach used to test genetic main effects...
- Antibiotic resistance in the environment: a link to the clinic?
Gerard D Wright
M G DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada L8N 3Z5
Curr Opin Microbiol 13:589-94. 2010
..Understanding the extent of the environmental resistome and its mobilization into pathogenic bacteria is essential for the management and discovery of antibiotics...
- The mental and physical health outcomes of green exercise
Department of Biological Sciences, University of Essex, Colchester, UK
Int J Environ Health Res 15:319-37. 2005
..We conclude that green exercise has important public and environmental health consequences...
- Individual, social, and physical environment factors associated with electronic media use among children: sedentary behavior at home
School of Sport Science, Exercise, and Health, The University of Western Australia, Perth, Australia
J Phys Act Health 8:613-25. 2011
Individual, home social and physical environment correlates of electronic media (EM) use among children were examined and pattern of differences on school and weekend days.
- Genes and social behavior
Gene E Robinson
Department of Entomology, University of Illinois at Urbana Champaign, 505 South Goodwin Avenue, Urbana, IL 61801, USA
Science 322:896-900. 2008
..We also discuss how evolutionary changes in genomic elements influence social behavior and outline prospects for a systems biology of social behavior...
- Resolving the infection process reveals striking differences in the contribution of environment, genetics and phylogeny to host-parasite interactions
University of Basel, Zoological Institute, Vesalgasse 1, Basel, Switzerland
BMC Biol 9:11. 2011
- Using environmental correlations to identify loci underlying local adaptation
Department of Evolution and Ecology and Center for Population Biology, University of California, Davis, Calfornia 95616, USA
Genetics 185:1411-23. 2010
..Software is available at http://www.eve.ucdavis.edu/gmcoop/...
- Phenotypic plasticity in the interactions and evolution of species
A A Agrawal
Department of Botany, University of Toronto, 25 Willcocks Street, Toronto, ON M5S 3B2, Canada
Science 294:321-6. 2001
..Taken together, phenotypic responses in species interactions represent modifications that can lead to reciprocal change in ecological time, altered community patterns, and expanded evolutionary potential of species...
- Adaptive prediction of environmental changes by microorganisms
Department of Molecular Genetics, Weizmann Institute of Science Rehovot 76100, Israel
Nature 460:220-4. 2009
..Our work indicates that environmental anticipation is an adaptive trait that was repeatedly selected for during evolution and thus may be ubiquitous in biology...
- Gene duplication as a mechanism of genomic adaptation to a changing environment
Fyodor A Kondrashov
Institucio Catalana de Recerca i Estudis Avancats, Centre for Genomic Regulation CRG and Universitat Pompeu Fabra, 88 Dr Aiguader, Barcelona 08003, Spain
Proc Biol Sci 279:5048-57. 2012
- Environment can alter selection in host-parasite interactions
Ludwig Maximilians Universitat, Department Biologie II, Evolutionsökologie, Grosshaderner Str 2, D 82152 Planegg Martinsried, Germany
Trends Parasitol 25:236-44. 2009
..Infections measured under laboratory conditions have shown that the environment in which hosts and parasites interact might substantially affect the strength and specificity of selection...
- C. elegans dauer formation and the molecular basis of plasticity
Huffington Center on Aging, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
Genes Dev 22:2149-65. 2008
..dynamic, and complex, all animals have evolved remarkable abilities to cope with changes in their external environment and internal physiology...
- Motor protein KIF1A is essential for hippocampal synaptogenesis and learning enhancement in an enriched environment
Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo, Tokyo 113 0033, Japan
Neuron 73:743-57. 2012
..of kinesin superfamily motor protein 1A (KIF1A) was observed in the hippocampi of mice kept in an enriched environment and, in hippocampal neurons in vitro, BDNF increased the levels of KIF1A and of KIF1A-mediated cargo transport...
- The influence of oral health conditions, socioeconomic status and home environment factors on schoolchildren's self-perception of quality of life
Janice S Paula
Department of Community Dentistry, Division of Health Education and Health Promotion, Piracicaba Dental School, P, O, Box 52, University of Campinas UNICAMP, 13414 903, Piracicaba, SP, Brazil
Health Qual Life Outcomes 10:6. 2012
The objective this study was to investigate the influence of clinical conditions, socioeconomic status, home environment, subjective perceptions of parents and schoolchildren about general and oral health on schoolchildren's oral health-..
- Neuronal basis of sequential foraging decisions in a patchy environment
Benjamin Y Hayden
Department of Neurobiology, Duke University School of Medicine, Durham, North Carolina, USA
Nat Neurosci 14:933-9. 2011
..These findings portend an understanding of the neural basis of foraging decisions and endorse the unification of theoretical and experimental work in ecology and neuroscience...
- Gene-environment interactions in human diseases
David J Hunter
Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, Massachusetts 02115, USA
Nat Rev Genet 6:287-98. 2005
Studies of gene-environment interactions aim to describe how genetic and environmental factors jointly influence the risk of developing a human disease...
- Neighborhood food environment and walkability predict obesity in New York City
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Environ Health Perspect 117:442-7. 2009
Differences in the neighborhood food environment may contribute to disparities in obesity.
- Bounded integration in parietal cortex underlies decisions even when viewing duration is dictated by the environment
Howard Hughes Medical Institute, National Primate Research Center, and Department of Physiology and Biophysics, University of Washington, Seattle, Washington 98195, USA
J Neurosci 28:3017-29. 2008
..Under many natural circumstances and in many laboratory settings, the environment, rather than the subject, controls the stimulus duration...
- The epigenome: archive of the prenatal environment
Bastiaan T Heijmans
Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
Epigenetics 4:526-31. 2009
..Well-designed epigenome-wide studies will be crucial in creating a catalog of epigenomic regions that are sensitive to the prenatal environment to evaluate developmental influences on common human disease.
- Relationship between the physical environment and physical activity in older adults: a systematic review
Jelle Van Cauwenberg
Department of Human Biometry and Biomechanics, Faculty of Physical Education and Physical Therapy, Vrije Universiteit Brussel, Pleinlaan 2, B 1050 Brussel, Belgium
Health Place 17:458-69. 2011
..aims to provide a comprehensive overview of the literature concerning the relationship between the physical environment and PA in older adults. A systematic literature search resulted in the inclusion of 31 articles...
- The Power of Food Scale. A new measure of the psychological influence of the food environment
Michael R Lowe
Department of Psychology, Drexel University, Philadelphia, PA 19102, USA
Appetite 53:114-8. 2009
..The PFS may be useful as a measure of the hedonic impact of food environments replete with highly palatable foods...
- Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics
Tamara B Harris
Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD 20892 9205, USA
Am J Epidemiol 165:1076-87. 2007
In anticipation of the sequencing of the human genome and description of the human proteome, the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik) was initiated in 2002...
- Anthropogenic environmental change and the emergence of infectious diseases in wildlife
Institute of Ecology, University of Georgia, Athens GA 30602, USA
Acta Trop 78:103-16. 2001
- The environment and susceptibility to schizophrenia
Alan S Brown
Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
Prog Neurobiol 93:23-58. 2011
..and more rigorous epidemiologic investigations, and research on translational and clinical neuroscience, gene-environment interactions, epigenetics, developmental trajectories and windows of vulnerability, are elaborated upon...
- Contributions of the environment and environmentally vulnerable physiology to autism spectrum disorders
Martha R Herbert
TRANSCEND Research Program, Pediatric Neurology, Massachusetts General Hospital, Charlestown, Massachusetts, USA
Curr Opin Neurol 23:103-10. 2010
..This review presents a rationale and evidence for contributions of environmental influences and environmentally vulnerable physiology to autism spectrum disorders (ASDs)...
- Measuring the food environment using geographical information systems: a methodological review
UMR INSERM U 557 INRA U 1125 CNAM, University Paris 13, CRNH IdF, Bobigny, France
Public Health Nutr 13:1773-85. 2010
Through a literature review, we investigated the geographic information systems (GIS) methods used to define the food environment and the types of spatial measurements they generate.
- Twin studies in autoimmune disease: genetics, gender and environment
Dimitrios P Bogdanos
Institute of Liver Studies, Liver Immunopathology, King s College London School of Medicine at King s College Hospital, London, UK
J Autoimmun 38:J156-69. 2012
..This review will examine the literature surrounding twin studies in autoimmune disease including discussions of genetics and gender...
- Unhealthy landscapes: Policy recommendations on land use change and infectious disease emergence
Jonathan A Patz
Center for Sustainability and the Global Environment SAGE, Nelson Institute for Environmental Studies and the Department of Population Health Sciences, University of Wisconsin, Madison, 53726 4087, USA
Environ Health Perspect 112:1092-8. 2004
- Built environment, physical activity, and obesity: what have we learned from reviewing the literature?
Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093, USA
Health Place 18:100-5. 2012
To evaluate the growing literature on the built environment and physical activity/obesity, we conducted a review of review papers...
- Epigenetic programming of neurodegenerative diseases by an adverse environment
Department of Biological Sciences, University of Lethbridge, Lethbridge, Alberta, Canada
Brain Res 1444:96-111. 2012
Experience and environment can critically influence the risk and progression of neurodegenerative disorders...
- Flowering time quantitative trait Loci analysis of oilseed brassica in multiple environments and genomewide alignment with Arabidopsis
National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, China
Genetics 177:2433-44. 2007
..Five to 18 QTL at a statistically significant level (SL-QTL) were detected in each environment and, on average, two new SL-QTL were discovered with each added environment...
- On the generality of the latitudinal diversity gradient
Department of Limnology, Evolutionary Biology Centre, University of Uppsala, Norr Malma 4200, S 76173 Norrtalje, Sweden
Am Nat 163:192-211. 2004
..This analysis is the first to describe these general and significant patterns, which have important consequences for models aiming to explain the latitudinal gradient...
- Limiting the impact of light pollution on human health, environment and stellar visibility
Istituto di Scienza e Tecnologia dell Inquinamento Luminoso, Via Roma 13, I 36106 Thiene, Italy
J Environ Manage 92:2714-22. 2011
..This increase will exacerbate known and possible unknown effects of light pollution on human health, environment and on visual perception of the Universe by humans...
- Environmental enrichment, prefrontal cortex, stress, and aging of the brain
Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, Madrid 28040, Spain
J Neural Transm 116:1007-16. 2009
As a result of living in an enriched environment, the brain of animals undergoes molecular and morphological changes leading to improvements in learning and memory...
- Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction
Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
Biol Psychiatry 57:1117-27. 2005
..The vast majority of cannabis users do not develop psychosis, however, prompting us to hypothesize that some people are genetically vulnerable to the deleterious effects of cannabis...
- Environmental and psychosocial correlates of accelerometer-assessed and self-reported physical activity in Belgian adults
Delfien Van Dyck
Fund for Scientific Research Flanders, Ghent, Belgium
Int J Behav Med 18:235-45. 2011
..To develop effective interventions to increase PA, it is necessary to understand the most important PA correlates and to investigate whether correlates are similar in different population subgroups...
- Atopic disease, immune system, and the environment
Department of Pediatrics, Catania University, Catania, Italy
Allergy Asthma Proc 28:410-7. 2007
..of allergic respiratory diseases observed in the last 20 years seems to be associated with changes of environment and lifestyle, which favor a delayed acquisition of Th1 function in childhood...
- An approximately Bayesian delta-rule model explains the dynamics of belief updating in a changing environment
Matthew R Nassar
Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Neurosci 30:12366-78. 2010
..appropriate beliefs about variables needed for effective decision making can be difficult in a dynamic environment. One key issue is the amount of influence that unexpected outcomes should have on existing beliefs...
- Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits
Department of Psychology, and Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA
Am J Psychiatry 167:509-27. 2010
..The study of such Gene-by-Environment (GxE) interactions has gained momentum...
- The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions
Marilyn C Cornelis
Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115
Genet Epidemiol 34:364-72. 2010
..However, the role of environment and its potential to interact with key loci has not been adequately addressed in most GWAS...
- Epigenetic mechanisms and cancer: an interface between the environment and the genome
Epigenetics Group, International Agency for Research on Cancer IARC, Lyon, France
Epigenetics 6:804-19. 2011
Although epidemiological studies support the role of environment in a wide range of human cancers, the precise mechanisms by which environmental exposures promote cancer development and progression remain poorly understood...
- Gene--environment-wide association studies: emerging approaches
Medicine, University of Southern California, 1540 Alcazar Street, CHP 220, Los Angeles, California 90089 9011, USA
Nat Rev Genet 11:259-72. 2010
..This unexplained heritability could be partly due to gene--environment (G×E) interactions or more complex pathways involving multiple genes and exposures...
- Clonal adaptive radiation in a constant environment
School of Molecular and Microbial Biosciences, University of Sydney, Sydney, New South Wales 2006, Australia
Science 313:514-7. 2006
..The multidirectional exploration of fitness space is an underestimated ingredient to bacterial success even in unstructured environments...
- Adaptation to an extraordinary environment by evolution of phenotypic plasticity and genetic assimilation
Division of Biology, Imperial College London, Silwood Park, Ascot, Berkshire, UK
J Evol Biol 22:1435-46. 2009
Adaptation to a sudden extreme change in environment, beyond the usual range of background environmental fluctuations, is analysed using a quantitative genetic model of phenotypic plasticity...
- A serpentinite-hosted ecosystem: the Lost City hydrothermal field
Deborah S Kelley
School of Oceanography, University of Washington, Seattle, WA 98195, USA
Science 307:1428-34. 2005
- Functional traits and environmental filtering drive community assembly in a species-rich tropical system
Wageningen University, Forest Ecology and Forest Management Group, Centre for Ecosystem Studies, P O Box 47, 6700 AA, Wageningen, The Netherlands
Ecology 91:386-98. 2010
..measurements and scale up from species to community level and because the functional traits' significance is environment dependent...
- Gene X environment interaction of vigorous exercise and body mass index among male Vietnam-era twins
Jeanne M McCaffery
Weight Control and Diabetes Research Center, Brown Medical School and The Miriam Hospital, Providence, RI 02903, USA
Am J Clin Nutr 89:1011-8. 2009
..However, twin models that incorporate a gene-environment correlation and gene x environment interaction have not been applied to elucidate specific environmental ..
- Immigration history controls diversification in experimental adaptive radiation
Department of Zoology, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA
Nature 446:436-9. 2007
..These results demonstrate that immigration and diversification are tightly linked processes, with small differences in immigration history greatly affecting the evolutionary emergence of diversity...
- Prion transmission: prion excretion and occurrence in the environment
Kevin C Gough
School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, UK
Prion 4:275-82. 2010
..The cycle of "uptake of prion from the environment--widespread in vivo prion dissemination--prion excretion--prion persistence in the environment" is likely to ..
- Global patterns in biodiversity
K J Gaston
Department of Animal and Plant Sciences, University of Sheffield, UK
Nature 405:220-7. 2000
..Theory is, however, developing rapidly, improving in its internal consistency, and more readily subjected to empirical challenge...
- Gene-environment interactions in obesity
Marion M Hetherington
Institute of Psychological Sciences, University of Leeds, Leeds, UK
Forum Nutr 63:195-203. 2010
..Common obesity is polygenic, involving complex gene-gene and gene-environment interactions, and it is these interactions that produce the multi-factorial obese phenotypes...
- Escherichia coli mechanisms of copper homeostasis in a changing environment
Department of Soil, Water, and Environmental Science, University of Arizona, Shantz Bld 38, Rm 429, Tucson, AZ 85721, USA
FEMS Microbiol Rev 27:197-213. 2003
..Pathways of copper uptake and intracellular copper handling are still not identified in E. coli...
- The presence of the glycolysis operon in SAR11 genomes is positively correlated with ocean productivity
M S Schwalbach
Oregon State University, Department of Microbiology, 220 Nash Hall, Corvallis, OR 97331, USA
Environ Microbiol 12:490-500. 2010
..Our results indicated that glycolysis is a variable metabolic property of SAR11 metabolism and suggest that glycolytic SAR11 are more common in productive marine environments...
- Specialization can drive the evolution of modularity
Department of Biochemistry, University of Zurich, Zurich, Switzerland
PLoS Comput Biol 6:e1000719. 2010
..We also show how modularity can facilitate co-option, the utilization of existing gene activity to build new gene activity patterns, a frequent feature of evolutionary innovations...
- Adaptive sugar provisioning controls survival of C. elegans embryos in adverse environments
Harold N Frazier
Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, WA 98195, USA
Curr Biol 19:859-63. 2009
..Such parental effects are adaptive for the offspring if the future environment is similar to the current one but can be maladaptive otherwise ...
- Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms
Kerry J Ressler
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 954 Gatewood Drive, Atlanta, GA 30329, USA
Am J Med Genet B Neuropsychiatr Genet 153:812-24. 2010
Gene x environment (G x E) interactions mediating depressive symptoms have been separately identified in the stress-sensitive serotonergic (5-HTTLPR) and corticotropin-releasing hormone (CRHR1) systems...
- Gene-environment interactions in Parkinson's disease: the importance of animal modeling
M P Horowitz
Medical Scientist Training Program, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Clin Pharmacol Ther 88:467-74. 2010
..We argue that animal modeling will become increasingly important in attempting to elucidate gene-environment interactions, to define pathogenic mechanisms, and to provide a platform for testing of targeted therapeutic ..