respiration

Summary

Summary: The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).

Top Publications

  1. pmc Astrocytes control breathing through pH-dependent release of ATP
    Alexander V Gourine
    Neuroscience, Physiology, and Pharmacology, University College London, London WC1E 6BT, UK
    Science 329:571-5. 2010
  2. pmc The effect of respiration variations on independent component analysis results of resting state functional connectivity
    Rasmus M Birn
    Section on Functional Imaging Methods, Laboratory of Brain and Cognition, National Institute of Mental Health, NIH, Bethesda, Maryland 20892 1148, USA
    Hum Brain Mapp 29:740-50. 2008
  3. pmc Influenza virus in human exhaled breath: an observational study
    Patricia Fabian
    Work Environment Department, University of Massachusetts Lowell, Lowell, Massachusetts, United States of America
    PLoS ONE 3:e2691. 2008
  4. ncbi The sniff as a unit of olfactory processing
    Adam Kepecs
    Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Chem Senses 31:167-79. 2006
  5. ncbi Physiology of diving of birds and mammals
    P J Butler
    School of Biological Sciences, The University of Birmingham, Edgbaston, United Kingdom
    Physiol Rev 77:837-99. 1997
  6. ncbi Respiratory changes in aortic blood velocity as an indicator of fluid responsiveness in ventilated patients with septic shock
    M Feissel
    , Centre Hospitalier, Belfort, France
    Chest 119:867-73. 2001
  7. pmc Sniffing behavior of mice during performance in odor-guided tasks
    Daniel W Wesson
    Department of Biology, Boston University, Boston, MA 02215, USA
    Chem Senses 33:581-96. 2008
  8. ncbi Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy
    Yvette Seppenwoolde
    Department of Radiotherapy, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    Int J Radiat Oncol Biol Phys 53:822-34. 2002
  9. doi Hindbrain interneurons and axon guidance signaling critical for breathing
    Julien Bouvier
    Institut de Neurobiologie Alfred Fessard, CNRS UPR 3294, Gif sur Yvette, France
    Nat Neurosci 13:1066-74. 2010
  10. ncbi Phosphine resistance, respiration rate and fitness consequences in stored-product insects
    Marco Aurélio G Pimentel
    Departamento de Biologia Animal, Universidade Federal de Vicosa, Vicosa, MG 36570 000, Brazil
    Pest Manag Sci 63:876-81. 2007

Detail Information

Publications279 found, 100 shown here

  1. pmc Astrocytes control breathing through pH-dependent release of ATP
    Alexander V Gourine
    Neuroscience, Physiology, and Pharmacology, University College London, London WC1E 6BT, UK
    Science 329:571-5. 2010
    ..This demonstrates a potentially crucial role for brain glial cells in mediating a fundamental physiological reflex...
  2. pmc The effect of respiration variations on independent component analysis results of resting state functional connectivity
    Rasmus M Birn
    Section on Functional Imaging Methods, Laboratory of Brain and Cognition, National Institute of Mental Health, NIH, Bethesda, Maryland 20892 1148, USA
    Hum Brain Mapp 29:740-50. 2008
    ..These slower respiration-induced signal changes occur at low frequencies and spatial locations similar to the fluctuations used to infer ..
  3. pmc Influenza virus in human exhaled breath: an observational study
    Patricia Fabian
    Work Environment Department, University of Massachusetts Lowell, Lowell, Massachusetts, United States of America
    PLoS ONE 3:e2691. 2008
    ..Recent studies suggest that humans exhale fine particles during tidal breathing but little is known of their composition, particularly during infection...
  4. ncbi The sniff as a unit of olfactory processing
    Adam Kepecs
    Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Chem Senses 31:167-79. 2006
    ..studies-primarily from anesthetized rodents-demonstrating that olfactory neural responses are coupled to respiration. Hence, the "sniff cycle" might play a role in odor coding, by allowing the timing of spikes with ..
  5. ncbi Physiology of diving of birds and mammals
    P J Butler
    School of Biological Sciences, The University of Birmingham, Edgbaston, United Kingdom
    Physiol Rev 77:837-99. 1997
    ..Efferent cardiac control is largely parasympathetic. Reflex cardiorespiratory responses are modulated by conditioning and habituation, but reflexes predominate during extended dives and during recovery, when gas exchange is maximized...
  6. ncbi Respiratory changes in aortic blood velocity as an indicator of fluid responsiveness in ventilated patients with septic shock
    M Feissel
    , Centre Hospitalier, Belfort, France
    Chest 119:867-73. 2001
    ....
  7. pmc Sniffing behavior of mice during performance in odor-guided tasks
    Daniel W Wesson
    Department of Biology, Boston University, Boston, MA 02215, USA
    Chem Senses 33:581-96. 2008
    ..We found that respiration frequencies in quiescent mice ranged from 3 to 5 Hz--higher than that reported for rats...
  8. ncbi Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy
    Yvette Seppenwoolde
    Department of Radiotherapy, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    Int J Radiat Oncol Biol Phys 53:822-34. 2002
    ..Understanding the behavior of tumor motion in lung tissue to model tumor movement is necessary for accurate (gated or breath-hold) radiotherapy or CT scanning...
  9. doi Hindbrain interneurons and axon guidance signaling critical for breathing
    Julien Bouvier
    Institut de Neurobiologie Alfred Fessard, CNRS UPR 3294, Gif sur Yvette, France
    Nat Neurosci 13:1066-74. 2010
    ....
  10. ncbi Phosphine resistance, respiration rate and fitness consequences in stored-product insects
    Marco Aurélio G Pimentel
    Departamento de Biologia Animal, Universidade Federal de Vicosa, Vicosa, MG 36570 000, Brazil
    Pest Manag Sci 63:876-81. 2007
    ..In all three species there was significant association (P < 0.05) between respiration rate and phosphine resistance...
  11. ncbi The use of active breathing control (ABC) to reduce margin for breathing motion
    J W Wong
    Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI 48073 6769, USA
    Int J Radiat Oncol Biol Phys 44:911-9. 1999
    ..Treatment planning and delivery can then be performed at identical ABC conditions with minimal margin for breathing motion...
  12. doi Central cholinergic regulation of respiration: nicotinic receptors
    Xuesi M Shao
    Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1763, USA
    Acta Pharmacol Sin 30:761-70. 2009
    ..These receptors mediate central cholinergic regulation of respiration and effects of the exogenous ligand nicotine on respiratory pattern...
  13. pmc Determination of comprehensive arterial blood inflow in abdominal-pelvic organs: impact of respiration and posture on organ perfusion
    Takuya Osada
    Department of Sports Medicine for Health Promotion, Tokyo Medical University, Tokyo, Japan
    Med Sci Monit 17:CR57-66. 2011
    ..However, little information exists regarding the influence of respiration (interplay between inspiration and expiration) and posture on BFAP.
  14. doi Choice of nasal nitric oxide technique as first-line test for primary ciliary dyskinesia
    J K Marthin
    Danish PCD Center, Paediatric Pulmonary Service, 5003, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Eur Respir J 37:559-65. 2011
    ..nNO is a helpful first-line tool in real-life PCD work-up in all age groups if the sampling method is chosen according to age. nNO can be misleading in a few patients with true PCD. Further studies are strongly needed in young children...
  15. doi Neuroanatomical characteristics of the human pre-Bötzinger complex and its involvement in neurodegenerative brainstem diseases
    Stephan W Schwarzacher
    Institute of Clinical Neuroanatomy, Neuroscience Center, Goethe University, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Brain 134:24-35. 2011
    ....
  16. ncbi Inspiratory muscle training improves maximal inspiratory pressure and may assist weaning in older intubated patients: a randomised trial
    Samária Ali Cader
    University Federal do Estada do Rio de Janiero LABIMH UNIRIO, Brazil
    J Physiother 56:171-7. 2010
    ..Does inspiratory muscle training improve maximal inspiratory pressure in intubated older people? Does it improve breathing pattern and time to wean from mechanical ventilation?..
  17. ncbi Detection and compensation of organ/lesion motion using 4D-PET/CT respiratory gated acquisition techniques
    Valentino Bettinardi
    Nuclear Medicine, San Raffaele Scientific Institute, Milan, Italy
    Radiother Oncol 96:311-6. 2010
    ..To describe the degradation effects produced by respiratory organ and lesion motion on PET/CT images and to define the role of respiratory gated (RG) 4D-PET/CT techniques to compensate for such effects...
  18. ncbi Relationship between airway narrowing, patchy ventilation and lung mechanics in asthmatics
    N T Tgavalekos
    Department of Anesthesia and Critical Care CLN 237F, Massachusetts General Hospital, and Department of Biomedical Engineering, Boston University, Boston 02114, USA
    Eur Respir J 29:1174-81. 2007
    ..The current data supports the concept that patchy ventilation is an expression of the integrated system and not just the sum of independent responses of individual airways...
  19. pmc Connexin hemichannel-mediated CO2-dependent release of ATP in the medulla oblongata contributes to central respiratory chemosensitivity
    Robert T R Huckstepp
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    J Physiol 588:3901-20. 2010
    ..We therefore propose that Cx26-mediated release of ATP in response to changes in PCO2 is an important mechanism contributing to central respiratory chemosensitivity...
  20. pmc Lung volume, breathing pattern and ventilation inhomogeneity in preterm and term infants
    Philipp Latzin
    Division of Respiratory Medicine, Department of Paediatrics, Inselspital and University of Bern, Bern, Switzerland
    PLoS ONE 4:e4635. 2009
    ..Although some studies have shown lower lung volumes and increased ventilation inhomogeneity in BPD infants, conflicting results exist possibly due to differences in sedation and measurement techniques...
  21. pmc Symbolic dynamic analysis of relations between cardiac and breathing cycles in patients on weaning trials
    P Caminal
    Departament ESAII, Universitat Politecnica de Catalunya UPC, Pau Gargallo, 5, 08028 Barcelona, Spain
    Ann Biomed Eng 38:2542-52. 2010
    ....
  22. pmc Chronic intermittent hypoxia enhances cat chemosensory and ventilatory responses to hypoxia
    Sergio Rey
    Laboratorio de Neurobiologia, Facultad de Ciencias Biologicas, P Universidad Católica of Chile, Santiago, Chile
    J Physiol 560:577-86. 2004
    ..Thus, the enhanced CB reactivity to hypoxia may contribute to the augmented ventilatory response to hypoxia, as well as to modified heart rate variability due to early changes in autonomic activity...
  23. pmc Peripheral mechanisms for vocal production in birds - differences and similarities to human speech and singing
    Tobias Riede
    Department of Biology and National Center for Voice and Speech, University of Utah, Salt Lake City, 84112, USA
    Brain Lang 115:69-80. 2010
    ..As in humans, bird phonation involves three main motor systems (respiration, vocal organ and vocal tract)...
  24. ncbi Characterization of successful and failed autoresuscitation in human infants, including those dying of SIDS
    Raghunathan Sridhar
    Division of Newborn Medicine, Department of Pediatrics, Washington University, St Louis, Missouri 63110, USA
    Pediatr Pulmonol 36:113-22. 2003
    ..Some SIDS infants appear to be different from infants dying with other diagnoses with respect to efficacy and characteristics of hypoxic gasping...
  25. pmc Impaired respiratory and body temperature control upon acute serotonergic neuron inhibition
    Russell S Ray
    Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
    Science 333:637-42. 2011
    ..of the ligand clozapine-N-oxide (CNO) by systemic injection attenuated the chemoreflex that normally increases respiration in response to tissue carbon dioxide (CO(2)) elevation and acidosis...
  26. ncbi Effect of heliox breathing on dynamic hyperinflation in COPD patients
    Matteo Pecchiari
    Istituto di Fisiologia Umana I, Universita di Milano, Milan, Italy
    Chest 125:2075-82. 2004
    ..Helium-oxygen mixtures (ie, heliox) have been used in treating these patients on the assumption that, by lowering airway resistance, they might be beneficial...
  27. ncbi Respiratory patterns and oxygen consumption in singing zebra finches
    Michele Franz
    Department of Biology, University of Utah, Salt Lake City, UT 84112, USA
    J Exp Biol 206:967-78. 2003
    ..We investigated the effect of the song motor pattern on respiration using a newly developed mask system to measure oxygen consumption while simultaneously monitoring subsyringeal ..
  28. ncbi Respiratory variations in pulse oximetry plethysmographic waveform amplitude to predict fluid responsiveness in the operating room
    Maxime Cannesson
    Hospices Civils de Lyon, Department of Anesthesiology and Intensive Care, Louis Pradel Hospital, Claude Bernard Lyon I University, France
    Anesthesiology 106:1105-11. 2007
    ..The authors hypothesized that DeltaPOP can predict fluid responsiveness in mechanically ventilated patients during general anesthesia...
  29. ncbi The management of respiratory motion in radiation oncology report of AAPM Task Group 76
    Paul J Keall
    Virginia Commonwealth University, USA
    Med Phys 33:3874-900. 2006
    ..methods, respiratory gated techniques, breath-hold techniques, forced shallow-breathing methods, and respiration-synchronized techniques...
  30. ncbi Sleep apnea syndrome in Parkinson's disease. A case-control study in 49 patients
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, Luxembourg
    Mov Disord 20:1413-8. 2005
    In PD, the impact of nocturnal respiration on sleep continuity and architecture has not been systematically investigated by polysomnography (PSG)...
  31. pmc Photostimulation of retrotrapezoid nucleus phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats
    Stephen B G Abbott
    Department of Pharmacology, University of Virginia, Charlottesville, Virginia 22908, USA
    J Neurosci 29:5806-19. 2009
    ..These results provide strong evidence that the Phox2b-expressing noncatecholaminergic neurons of the RTN region function as central respiratory chemoreceptors...
  32. ncbi St. George's Respiratory Questionnaire: MCID
    Paul W Jones
    St George s Hospital Medical School, London, UK
    COPD 2:75-9. 2005
    ....
  33. doi Defects in breathing and thermoregulation in mice with near-complete absence of central serotonin neurons
    Matthew R Hodges
    Department of Neurology, Yale University, New Haven, Connecticut 06520, USA
    J Neurosci 28:2495-505. 2008
    ..We conclude that the proper function of the 5-HT system is particularly important under conditions of environmental stress and contributes significantly to the hypercapnic ventilatory response and thermoregulatory cold defense...
  34. ncbi Slow breathing increases arterial baroreflex sensitivity in patients with chronic heart failure
    Luciano Bernardi
    Department of Internal Medicine, University of Pavia and IRCCS Ospedale S Matteo, Pavia, Italy
    Circulation 105:143-5. 2002
    ..It is well established that a depressed baroreflex sensitivity may adversely influence the prognosis in patients with chronic heart failure (CHF) and in those with previous myocardial infarction...
  35. ncbi Short-term variability of respiration and sleep during unattended nonlaboratory polysomnography--the Sleep Heart Health Study. [corrected]
    Stuart F Quan
    Arizona Respiratory Center and Department of Medicine, University of Arizona College of Medicine, Tucson, AZ 85724, USA
    Sleep 25:843-9. 2002
    To determine the short-term variability of indices of disturbed respiration and sleep during 2 nights of unattended nonlaboratory polysomnography conducted several months apart.
  36. ncbi Recruitment and derecruitment during acute respiratory failure: an experimental study
    P Pelosi
    Istituto di Anestesia e Rianimazione, , Ospedale Maggiore Policlinico-IRCCS, Milan, Italy
    Am J Respir Crit Care Med 164:122-30. 2001
    ..86, p < 0.0001), suggesting that as more tissue is recruited at end-inspiration, more remains recruited at end-expiration. When superimposed pressure exceeded applied airway pressure (Paw), collapse significantly increased...
  37. pmc Temporal structure of receptor neuron input to the olfactory bulb imaged in behaving rats
    Ryan M Carey
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    J Neurophysiol 101:1073-88. 2009
    ..input from olfactory receptor neurons (ORNs) are poorly characterized and depend on multiple factors, including respiration-driven airflow through the nasal cavity, odorant sorption kinetics, receptor-ligand interactions between ..
  38. doi HPA axis, respiration and the airways in stress--a review in search of intersections
    James L Abelson
    Stress and Anxiety Research Group, Department of Psychiatry Trauma, University of Michigan, Ann Arbor, MI 48109, USA
    Biol Psychol 84:57-65. 2010
    ..We examine HPA hormone effects on respiration, immune/inflammatory mediators, and lung maturation. We also examine respiratory/dyspnea effects on HPA axis...
  39. ncbi State-dependent modulation of breathing in urethane-anesthetized rats
    Silvia Pagliardini
    Department of Physiology, Centre for Neuroscience, and Women and Children s Health Research Institute, University of Alberta, Edmonton, Alberta T6G 2E1, Canada
    J Neurosci 32:11259-70. 2012
    ....
  40. ncbi Nasal airway measurements in children treated by rapid maxillary expansion
    Giacomo Ceroni Compadretti
    Department of Otorhinolaryngology, Imola Hospital, Imola, Italy
    Am J Rhinol 20:385-93. 2006
    ..The availability of a reliable and objective technique to assess the geometry of nasal cavities, such as acoustic rhinometry, stimulated the present investigation...
  41. doi Tracheal occlusions evoke respiratory load compensation and neural activation in anesthetized rats
    Kathryn M Pate
    Physiological Sciences, University of Florida, Gainesville, Florida 32603, USA
    J Appl Physiol (1985) 112:435-42. 2012
    ....
  42. doi Quantifying interfraction and intrafraction tumor motion in lung stereotactic body radiotherapy using respiration-correlated cone beam computed tomography
    Jean Pierre Bissonnette
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 75:688-95. 2009
    ..However, the precise extent of these changes in breathing pattern is not well known. We evaluated the inter- and intrafractional changes in tumor motion amplitude (DeltaM) over an SBRT course...
  43. doi Respiratory sinus arrhythmia in conscious humans during spontaneous respiration
    P D Larsen
    Department of Surgery and Anaesthesia, University of Otago, Wellington, Wellington South, New Zealand
    Respir Physiol Neurobiol 174:111-8. 2010
    ....
  44. ncbi Neuronal pacemaker for breathing visualized in vitro
    N Koshiya
    Cellular and Systems Neurobiology Section, Laboratory of Neural Control, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    Nature 400:360-3. 1999
    ..These results provide evidence that the neuronal kernel for rhythm generation consists of a network of synaptically-coupled pacemaker neurons...
  45. doi Interfraction and respiratory organ motion during conformal radiotherapy in gastric cancer
    Barbara Wysocka
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 77:53-9. 2010
    ..To quantify the interfraction and breathing organ motion during adjuvant radiotherapy for gastric cancer and assess organ stability in different breathing states...
  46. doi Four-dimensional measurement of the displacement of internal fiducial markers during 320-multislice computed tomography scanning of thoracic esophageal cancer
    Hideomi Yamashita
    Department of Radiology, University of Tokyo Hospital, Tokyo, Japan
    Int J Radiat Oncol Biol Phys 79:588-95. 2011
    ..To investigate the three-dimensional movement of internal fiducial markers placed near esophageal cancers using 320-multislice CT...
  47. pmc Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression
    Shilpa Iyer
    Center for the Study of Neurodegenerative Diseases and The Morris K Udall Parkinson s Disease Research Center of Excellence, University of Virginia, PO Box 800394, Charlottesville, VA 22908, United States
    Mitochondrion 9:196-203. 2009
    ..MTD-TFAM reversibly increased respiration and levels of respiratory proteins...
  48. ncbi Single breath-hold assessment of ventricular volumes using 32-channel coil technology and an extracellular contrast agent
    Victoria Parish
    Division of Imaging Sciences, NIHR Biomedical Research Centre at Guy s and St Thomas NHS Foundation Trust, King s College London, London, UK
    J Magn Reson Imaging 31:838-44. 2010
    ..To evaluate the feasibility of a single breath-hold 3D cine balanced steady-state free precession (b-SSFP) sequence after gadolinium diethylenetriamine penta-acetic acid (Gd-DTPA) injection for volumetric cardiac assessment...
  49. ncbi Electrophysiologic evaluation of Sudarshan Kriya: an EEG, BAER, P300 study
    M Bhatia
    Department of Neurology, All India Institute of Medical Sciences, New Delhi
    Indian J Physiol Pharmacol 47:157-63. 2003
    ..To compare the resting Electroencephalogram (EEG), Brainstem Auditory Evoked Responses (BAER) and P300 amongst trained and regular practitioners of Sudarshan Kriya (SK) GP-I and Controls (GP-II)...
  50. ncbi The sniff is part of the olfactory percept
    Joel Mainland
    Helen Wills Neuroscience Institute and Department of Psychology, University of California at Berkeley, Berkeley, CA 94720, USA
    Chem Senses 31:181-96. 2006
    ....
  51. ncbi Nonlinear measures of respiration: respiratory irregularity and increased chaos of respiration in patients with panic disorder
    Vikram Kumar Yeragani
    Department of Psychiatry, Wayne State University School of Medicine, Detroit, Mich, USA
    Neuropsychobiology 46:111-20. 2002
    ..In this study, we used these measures of respiration to compare normal controls (n = 18) and patients with panic disorder (n = 22) in addition to the traditional ..
  52. pmc The respiration response function: the temporal dynamics of fMRI signal fluctuations related to changes in respiration
    Rasmus M Birn
    Laboratory of Brain and Cognition, National Institute of Mental Health, 10 Center Dr, Bldg 10, Rm 1D80, Bethesda, MD 20892 1148, USA
    Neuroimage 40:644-54. 2008
    ..b>Respiration related signal changes appear to be slower than neuronally induced BOLD signal changes and are not modeled ..
  53. ncbi Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons
    Veronique Dubreuil
    Departement de Biologie, Ecole Normale Superieure, 75005 Paris, France
    J Neurosci 29:14836-46. 2009
    ..Together, our results provide genetic evidence for the essential role of the Phox2b-expressing RTN neurons both in establishing a normal respiratory rhythm before birth and in providing chemosensory drive...
  54. pmc Spatial organization and state-dependent mechanisms for respiratory rhythm and pattern generation
    Ilya A Rybak
    Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA
    Prog Brain Res 165:201-20. 2007
    ..The model predicts a continuum of respiratory network states relying on different contributions of intrinsic cellular properties versus synaptic interactions for the generation and control of the respiratory rhythm and pattern...
  55. ncbi Inferior vena cava percentage collapse during respiration is affected by the sampling location: an ultrasound study in healthy volunteers
    David J Wallace
    Department of Emergency Medicine, Kings County Hospital, Brooklyn, NY, USA
    Acad Emerg Med 17:96-9. 2010
    ..The objective of this study was to determine the importance of location when measuring the IVC diameter during quiet respiration.
  56. ncbi Simultaneous single unit recording in the mitral cell layer of the rat olfactory bulb under nasal and tracheal breathing
    María de la Luz Aylwin
    CENI, Iniciativa Científica Milenio y Programas de Fisiología y Biofísica, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Biol Res 38:13-26. 2005
    ..Surprisingly, nearly all single units exhibited a long refractory period averaging 14.4 ms during nasal respiration that was not different under tracheal breathing...
  57. ncbi A novel functional neuron group for respiratory rhythm generation in the ventral medulla
    Hiroshi Onimaru
    Showa University School of Medicine, Shinagawa ku, Tokyo 142 8555, Japan
    J Neurosci 23:1478-86. 2003
    ..Our findings suggest that the pFRG comprises a neuronal population that is involved in the primary respiratory rhythm generation in the rostrocaudally extending respiratory neuron network of the medulla...
  58. pmc Intensely pleasurable responses to music correlate with activity in brain regions implicated in reward and emotion
    A J Blood
    Montreal Neurological Institute, McGill University, Montreal, QC, Canada
    Proc Natl Acad Sci U S A 98:11818-23. 2001
    ..Subjective reports of chills were accompanied by changes in heart rate, electromyogram, and respiration. As intensity of these chills increased, cerebral blood flow increases and decreases were observed in brain ..
  59. doi Image-guided radiotherapy for liver cancer using respiratory-correlated computed tomography and cone-beam computed tomography
    Matthias Guckenberger
    Department of Radiation Oncology, Julius Maximilians University, Wuerzburg, Germany
    Int J Radiat Oncol Biol Phys 71:297-304. 2008
    ..To evaluate a novel four-dimensional (4D) image-guided radiotherapy (IGRT) technique in stereotactic body RT for liver tumors...
  60. ncbi Abdominal organ motion measured using 4D CT
    Edward D Brandner
    Department of Radiation Oncology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 19107, USA
    Int J Radiat Oncol Biol Phys 65:554-60. 2006
    To measure respiration-induced abdominal organ motion using four-dimensional computed tomography (4D CT) scanning and to examine the organ paths.
  61. ncbi Autonomic nervous system dysregulation: breathing and heart rate perturbation during wakefulness in young girls with Rett syndrome
    Debra E Weese-Mayer
    Pediatric Respiratory Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA
    Pediatr Res 60:443-9. 2006
    ..This dysregulation may offer insight into the mechanisms that render girls with RS more vulnerable to sudden death...
  62. ncbi Skeletal and occlusal characteristics in mouth-breathing pre-school children
    Sara Elisa M Mattar
    Department of Pediatric Dentistry, School of Dentistry, University of Uberaba, Brazil
    J Clin Pediatr Dent 28:315-8. 2004
    ..Based on the results of this study, mouth-breathing can influence craniofacial and occlusal development early in childhood...
  63. ncbi Detection of a relation between respiration and CSF pulsation with an echoplanar technique
    U Klose
    Section of Experimental MR of the CNS, Department of Neuroradiology, University of Tubingen, D 72076 Tubingen, Germany
    J Magn Reson Imaging 11:438-44. 2000
    ..Simultaneously with the image data acquisition, data from a pulse oximeter and a respiration belt were recorded...
  64. ncbi Evaluation of nasal airway resistance during rapid maxillary expansion using acoustic rhinometry
    Cenk Doruk
    Department of Orthodontics, Cumhuriyet University, Sivas, Turkey
    Eur J Orthod 26:397-401. 2004
    ..05). The use of a decongestant was not found to have any effect on the results. Subjective evaluation showed that 59 per cent of patients considered that their nasal breathing had improved following RME...
  65. ncbi Effects of motion on the total dose distribution
    Thomas Bortfeld
    Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    Semin Radiat Oncol 14:41-51. 2004
    ..An alternative to the use of margins is to do the planning based on blurred dose distributions...
  66. ncbi Pontine influences on breathing: an overview
    George F Alheid
    Department of Physiology and Institute for Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 3008, USA
    Respir Physiol Neurobiol 143:105-14. 2004
    ..Accordingly, a working definition of rostral and caudal pontine boundaries for adult mammals is depicted...
  67. pmc Selective lesioning of the cat pre-Bötzinger complex in vivo eliminates breathing but not gasping
    J M Ramirez
    Department of Physiology, University of Gottingen, D 37073 Gottingen, Germany
    J Physiol 507:895-907. 1998
    ..the pre-Bötzinger complex, it was still possible to induce gasping during hypoxia or asphyxia, indicating that respiration and gasping are generated by two different neuronal networks. 5...
  68. ncbi Discontinuous gas exchange in insects: a clarification of hypotheses and approaches
    Steven L Chown
    Spatial, Physiological, and Conservation Ecology Group, Department of Botany and Zoology, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa
    Physiol Biochem Zool 79:333-43. 2006
    ....
  69. ncbi Four-dimensional proton treatment planning for lung tumors
    Martijn Engelsman
    Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 64:1589-95. 2006
    In proton radiotherapy, respiration-induced variations in density lead to changes in radiologic path lengths and will possibly result in geometric misses...
  70. ncbi Inspiratory muscle training improves rowing performance
    S Volianitis
    School of Sport and Exercise Sciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom
    Med Sci Sports Exerc 33:803-9. 2001
    ..To investigate the effects of a period of resistive inspiratory muscle training (IMT) upon rowing performance...
  71. ncbi Ventilation and entrainment of breathing during cycling and running in triathletes
    M R Bonsignore
    Istituto di Scienze e Tecnologia dello Sport e dell Attività Fisica, Consiglio Nazionale delle Ricerche, Palermo, Italy
    Med Sci Sports Exerc 30:239-45. 1998
    ..To assess whether entrainment of breathing (E) during exercise: 1) differed according to the test protocol in well-trained triathletes, and 2) improved ventilatory efficiency during exercise...
  72. pmc Respiration of resting honeybees
    Helmut Kovac
    Institut fur Zoologie, Karl Franzens Universitat Graz, Universitatsplatz 2, A 8010 Graz, Austria
    J Insect Physiol 53:1250-61. 2007
    ..Larger bursts coincided with a longer duration of active ventilation. An increased amount of CO(2) expelled per unit time of ventilation indicates a higher efficiency of ventilation at high ambient temperatures...
  73. ncbi Piriform cortex functional heterogeneity revealed by cellular responses to odours
    P Litaudon
    Neurosciences et Systemes Sensoriels, Université Lyon I CNRS, 50 avenue Tony Garnier, 69366 Lyon Cedex 07, France
    Eur J Neurosci 17:2457-61. 2003
    ..Functional anatomy of the PC suggests that activity in the anterior PC can be mainly driven by afferent activity coming from the OB whereas posterior cells were certainly entrained by more complex mechanisms...
  74. ncbi Slow breathing reduces sympathoexcitation in COPD
    T Raupach
    Dept of Cardiology and Pneumology, Georg August University Gottingen, Gottingen, Germany
    Eur Respir J 32:387-92. 2008
    ..In conclusion, sympathovagal imbalance is present in normoxic chronic obstructive pulmonary disease patients. The possibility of modifying these changes by slow breathing may help to better understand and influence this systemic disease...
  75. ncbi Determining parameters for respiration-gated radiotherapy
    S S Vedam
    Department of Biomedical Engineering, Medical College of Virginia Hospitals at Virginia Commonwealth University, Richmond 23298, USA
    Med Phys 28:2139-46. 2001
    b>Respiration-gated radiotherapy for tumor sites affected by respiratory motion will potentially improve radiotherapy outcomes by allowing reduced treatment margins leading to decreased complication rates and/or increased tumor control...
  76. ncbi Attenuated defense response and low basal blood pressure in orexin knockout mice
    Yuji Kayaba
    Dept of Molecular and Integrative Physiology, Chiba Univ Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    Am J Physiol Regul Integr Comp Physiol 285:R581-93. 2003
    ....
  77. ncbi Pre-ejection period variations predict the fluid responsiveness of septic ventilated patients
    Marc Feissel
    Intensive Care Unit, Centre Hospitalier, Belfort, France
    Crit Care Med 33:2534-9. 2005
    ..We hypothesized that the respiratory change in pre-ejection period (DeltaPEP) would allow the prediction of changes in cardiac index following volume administration in mechanically ventilated septic patients...
  78. ncbi Orexin stimulates breathing via medullary and spinal pathways
    John K Young
    Dept of Anatomy, Howard Univ College of Medicine, 520 W St, NW, Washington, DC 20059, USA
    J Appl Physiol (1985) 98:1387-95. 2005
    A central neuronal network that regulates respiration may include hypothalamic neurons that produce orexin, a peptide that influences sleep and arousal...
  79. ncbi 4-dimensional computed tomography imaging and treatment planning
    Paul Keall
    Department of Radiation Oncology, Virginia Commonwealth University, Richmond 23298 0058, USA
    Semin Radiat Oncol 14:81-90. 2004
    ..This article discusses methodology for 4D CT imaging and 4D treatment planning, with some comments on 4D radiation delivery...
  80. ncbi Modulatory effects of respiration
    L Bernardi
    Dipartimento di Medicina Interna, University of Pavia, Italy
    Auton Neurosci 90:47-56. 2001
    b>Respiration is a powerful modulator of heart rate variability, and of baro- and chemoreflex sensitivity. Abnormal respiratory modulation of heart rate is often an early sign of autonomic dysfunction in a number of diseases...
  81. ncbi Respiratory units of motor production and song imitation in the zebra finch
    Michele Franz
    Department of Biology, University of Utah, 257 South 1400 East, Salt Lake City, UT 84112, USA
    J Neurobiol 51:129-41. 2002
    ..Switching between respiratory phases, therefore, appears to play a dominant role in organizing the stereotyped motor program for song production...
  82. ncbi Neural control of tongue movement with respect to respiration and swallowing
    A Sawczuk
    Department of Oral Pathology, University of Medicine and Dentistry of New Jersey, Newark 07103-2400, USA
    Crit Rev Oral Biol Med 12:18-37. 2001
    ..Particular attention will be given to the interaction of tongue movement with respiration and swallowing, because the morbidity and mortality associated with these relationships make this a primary ..
  83. ncbi Characterization of Drosophila hemoglobin. Evidence for hemoglobin-mediated respiration in insects
    Thomas Hankeln
    Institute of Molecular Genetics, Biosafety Research and Consulting, University of Mainz, D 55099 Mainz, Germany
    J Biol Chem 277:29012-7. 2002
    ..This suggests that oxygen supply in insects may be more complex than thought previously and may depend on hemoglobin-mediated oxygen transport and storage in addition to simple diffusion...
  84. ncbi Resting metabolic rate and respiratory quotient in human longevity
    M R Rizzo
    Department of Geriatric Medicine and Metabolic Diseases, II University of Naples, Italy
    J Clin Endocrinol Metab 90:409-13. 2005
    ..It is likely that the lack of the anthropometrics derangement may preserve long-lived subjects from the age-related decrease in energy metabolism...
  85. ncbi Free-breathing whole-heart coronary MRA with 3D radial SSFP and self-navigated image reconstruction
    C Stehning
    Institute of Biomedical Engineering, Karlsruhe, Germany
    Magn Reson Med 54:476-80. 2005
    ..A signal synchronous with respiration was extracted directly from the echoes acquired for imaging, and the motion information was used for ..
  86. ncbi Paradoxical respiratory sinus arrhythmia in the anesthetized rat
    Yu Chieh Tzeng
    Department of Surgery and Anesthesia, Wellington School of Medicine and Health Sciences, 23A Mein Street, Newtown, PO Box 7343, Wellington, New Zealand
    Auton Neurosci 118:25-31. 2005
    ..We conclude that RSA is not a suitable measure of vagal tone during anesthesia in the rat and reiterate the caution that needs to be taken when working with anesthetized experimental models of cardiac control...
  87. ncbi The maturation and coordination of sucking, swallowing, and respiration in preterm infants
    Katsumi Mizuno
    Division of Neonatology, Chiba Children s Hospital, Chiba City, Japan
    J Pediatr 142:36-40. 2003
    Our objectives were to establish normative maturational data for feeding behavior of preterm infants from 32 to 36 weeks of postconception and to evaluate how the relation between swallowing and respiration changes with maturation.
  88. ncbi Respiratory sinus arrhythmia. A phenomenon improving pulmonary gas exchange and circulatory efficiency
    J Hayano
    Third Department of Internal Medicine, Nagoya City University Medical School, Japan
    Circulation 94:842-7. 1996
    ..We hypothesized that RSA benefits pulmonary gas exchange by matching perfusion to ventilation within each respiratory cycle...
  89. ncbi Overall and peripheral inhomogeneity of ventilation in patients with stable cystic fibrosis
    A Van Muylem
    Department of Chest Medicine, Erasme University Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Pediatr Pulmonol 30:3-9. 2000
    ..In older CF patients, (S(SF6) - S(He)) is more often positive, suggesting that even more distal airways, such as alveolar ducts, become involved in peripheral inhomogeneity of ventilation...
  90. pmc Lung function and respiratory health in adolescents of very low birth weight
    D Anand
    FSID Unit of Perinatal and Paediatric Epidemiology, Department of Public Health, Liverpool, UK
    Arch Dis Child 88:135-8. 2003
    ....
  91. ncbi Automated monitoring of diaphragm end-expiratory position for real-time navigator echo MR coronary angiography
    A M Taylor
    Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom
    J Magn Reson Imaging 9:395-401. 1999
    Real-time navigator echo (NE)-gated magnetic resonance coronary angiography (MRCA) during free respiration is now possible...
  92. ncbi Ketamine-xylazine-induced slow (< 1.5 Hz) oscillations in the rat piriform (olfactory) cortex are functionally correlated with respiration
    Alfredo Fontanini
    Division of Biology, California Institute of Technology, Pasadena, California 91125, USA
    J Neurosci 23:7993-8001. 2003
    ..between the occurrence and timing of slow oscillations and the ongoing periodic sensory input resulting from respiration. This coupling between olfactory cortex slow oscillations and respiration may result from the interaction ..
  93. doi Effects of respiratory rate on ventilator-induced lung injury at a constant PaCO2 in a mouse model of normal lung
    Katerina Vaporidi
    Department of Intensive Care Medicine, University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Crete, Greece
    Crit Care Med 36:1277-83. 2008
    ..The aim of this study was to evaluate the effects of respiratory rate (RR) at a constant PaCO2 and conventional tidal volume (VT) on the development of ventilator-induced lung injury in normal lungs...
  94. doi Respiration-gated formation of gamma and beta neural assemblies in the mammalian olfactory bulb
    Tristan Cenier
    Neurosciences Sensorielles, Comportement, Cognition, Universite Claude Bernard Lyon1, CNRS UMR 5020, Institut Fédératif de Neurosciences de Lyon, 50 avenue Tony Garnier, 69366 Lyon cedex 7, France
    Eur J Neurosci 29:921-30. 2009
    ..At the same time, mitral/tufted (M/T) cells display respiration-modulated spiking patterns...
  95. ncbi Rhythm sequence through the olfactory bulb layers during the time window of a respiratory cycle
    Nathalie Buonviso
    Neurosciences et Systemes Sensoriels, Université Lyon I CNRS, 50 avenue Tony Garnier, 69366 Lyon Cedex 07, France
    Eur J Neurosci 17:1811-9. 2003
    ..We discuss the possibility that each rhythm could serve different functions as priming, gating or tuning for the bulbar network...
  96. ncbi Fluid responsiveness in spontaneously breathing patients: a review of indexes used in intensive care
    Alice Coudray
    Geneva University Hospital, Geneva, Switzerland
    Crit Care Med 33:2757-62. 2005
    ..The present review discusses the clinical utility and accuracy of indexes tested as bedside indicators of preload reserve and fluid responsiveness in hypotensive, spontaneously breathing patients...
  97. pmc Influence of differential expression of acetylcholinesterase in brain and muscle on respiration
    Eliane Boudinot
    Neurobiologie Genetique et Integrative, Institut de Neurobiologie Alfred Fessard, C N R S, 91190 Gif sur Yvette, France
    Respir Physiol Neurobiol 165:40-8. 2009
    ..To investigate the respective roles of AChE in brain and muscle, we recorded respiration by means of whole-body plethysmography in knockout mice with tissue selective deletions in AChE expression...
  98. pmc Neuroimaging of cerebral activations and deactivations associated with hypercapnia and hunger for air
    S Brannan
    Research Imaging Center, Medical School, University of Texas Health Science Center, Floyd Curl Drive, San Antonio, TX 78284, USA
    Proc Natl Acad Sci U S A 98:2029-34. 2001
    There are defined medullary, mesencephalic, hypothalamic, and thalamic functions in regulation of respiration, but knowledge of cortical control and the elements subserving the consciousness of breathlessness and air hunger is limited...
  99. pmc Lung structure phenotype variation in inbred mouse strains revealed through in vivo micro-CT imaging
    Jacqueline Thiesse
    Department of Internal Medicine, The University of Iowa, Iowa City, IA 52242, USA
    J Appl Physiol (1985) 109:1960-8. 2010
    ..In addition, using these techniques we have uncovered significant differences in the airway structures between inbred mouse strains in vivo...
  100. doi Potential dosimetric benefits of four-dimensional radiation treatment planning
    George Starkschall
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 73:1560-5. 2009
    ..To determine the extent of dosimetric differences between conventional three-dimensional (3D) dose calculations and four-dimensional (4D) dose calculations based on deformation of organ models...
  101. pmc Simultaneous magnetic resonance imaging of ventilation distribution and gas uptake in the human lung using hyperpolarized xenon-129
    John P Mugler
    Center for In vivo Hyperpolarized Gas MR Imaging, Department of Radiology, University of Virginia, Charlottesville, VA 22908
    Proc Natl Acad Sci U S A 107:21707-12. 2010
    ..This MRI-based method provides a way to quantify relationships among gas delivery, exchange, and transport, and appears to have significant potential to provide more insight into lung disease...

Research Grants91

  1. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..abstract_text> ..
  2. ECG-derived cardiopulmonary coupling biomarkers of sleep, sleep-breathing, and ca
    Robert J Thomas; Fiscal Year: 2010
    ..The traditional approach to quantifying sleep and sleep-respiration relies on manual or computer assisted scoring of 30 second epochs, tagging of discrete fast phasic ..
  3. ECG-derived cardiopulmonary coupling biomarkers of sleep, sleep-breathing, and ca
    Robert Thomas; Fiscal Year: 2009
    ..The traditional approach to quantifying sleep and sleep-respiration relies on manual or computer assisted scoring of 30 second epochs, tagging of discrete fast phasic ..
  4. EMA Assessment of Biobehavioral Processes in Human Pregnancy
    Pathik D Wadhwa; Fiscal Year: 2010
    ..Continuous ambulatory measures of maternal heart rate, respiration and physical activity, as well as seven saliva samples over the course of each day, will be collected for ..
  5. Arsenic Trioxide and Acute Myeloid Leukemia
    Yongkui Jing; Fiscal Year: 2010
    ..Under physiological conditions ROS generated as a byproduct of mitochondrial respiration are detoxified by glutathione-enzymes, glutathione peroxidase (GPx), glutathione-s-transferase ? (GST?) and ..
  6. Arsenic Trioxide and Acute Myeloid Leukemia
    Yongkui Jing; Fiscal Year: 2009
    ..Under physiological conditions ROS generated as a byproduct of mitochondrial respiration are detoxified by glutathione-enzymes, glutathione peroxidase (GPx), glutathione-s-transferase ? (GST?) and ..
  7. Bacterial Response to Singlet Oxygen
    Timothy Donohue; Fiscal Year: 2007
    ..planet; it is a product of oxygenic photosynthesis and it is a substrate for bioenergetic pathways like aerobic respiration. While O2 is relatively inert, it is converted to different chemical classes of toxic reactive oxygen species ..
  8. Central Respiratory Effects of Organophosphate Poisoning
    Romolo J Gaspari; Fiscal Year: 2010
    ..Paydarfar has extensive experience in respiration-related neurophysiology...
  9. Central Respiratory Effects of Organophosphate Poisoning
    Romolo Gaspari; Fiscal Year: 2009
    ..Paydarfar has extensive experience in respiration-related neurophysiology...
  10. Central Respiratory Effects of Organophosphate Poisoning
    Romolo Gaspari; Fiscal Year: 2009
    ..Paydarfar has extensive experience in respiration-related neurophysiology...
  11. Central Respiratory Effects of Organophosphate Poisoning
    Romolo Gaspari; Fiscal Year: 2007
    ..Paydarfar has extensive experience in respiration-related neurophysiology...
  12. Central Respiratory Effects of Organophosphate Poisoning
    Romolo Gaspari; Fiscal Year: 2006
    ..Paydarfar has extensive experience in respiration-related neurophysiology...
  13. SITE-SPECIFIC PROPERTIES OF A UNIQUE IRON-SULFUR PROTEIN
    Michael Adams; Fiscal Year: 1991
    ..They are intimately involved in such fundamental biological processes as respiration, photosynthesis, fermentation, and nitrogen fixation...
  14. Nitric Oxide in Pulmonary Hypertension
    Serpil Erzurum; Fiscal Year: 2009
    ..In association with low NO, the cells have reduced mitochondria numbers &respiration, which is accompanied by ~3-fold increase in glycolysis for energy production...
  15. Nitric Oxide in Pulmonary Hypertension
    Serpil C Erzurum; Fiscal Year: 2010
    ..In association with low NO, the cells have reduced mitochondria numbers &respiration, which is accompanied by ~3-fold increase in glycolysis for energy production...
  16. Developing Radiological Risk Communication Materials for Low-Literacy Populations
    Sarah Bass; Fiscal Year: 2009
    ..materials will then be tested using psycho- physiological measures (eye-tracking, pupil dilation, heart rate, respiration rate, skin conductance and body temperature) to assess their effectiveness in reducing fear and increasing ..
  17. SKELETAL MUSCLE ENERGY METABOLISM
    Martin Kushmerick; Fiscal Year: 1993
    ..of ATP (muATP), is viewed as the medium through which two important cell functions are regulated: mitochondrial respiration and muscle phenotypic expression...
  18. SKELETAL MUSCLE ENERGY METABOLISM
    Martin Kushmerick; Fiscal Year: 1992
    ..of ATP (muATP), is viewed as the medium through which two important cell functions are regulated: mitochondrial respiration and muscle phenotypic expression...
  19. SKELETAL MUSCLE ENERGY METABOLISM
    Martin Kushmerick; Fiscal Year: 1991
    ..of ATP (muATP), is viewed as the medium through which two important cell functions are regulated: mitochondrial respiration and muscle phenotypic expression...
  20. BROWN FAT DEFICIENT TRANSGENIC MICE
    JEFFREY FLIER; Fiscal Year: 1993
    ..It is distinguished by the presence of uncoupling protein (UCP), a mitochondrial transporter which uncouples respiration. Because of this highly specialized capability, dysfunction of BAT could play a critical role in the ..
  21. Novel 3D Catheter Tracking System for Intracardiac Navigation
    DORON HARLEV; Fiscal Year: 2009
    ..are all plagued by significant limitations, including tracking distortions and inadequate correction for respiration and other motion artifacts...
  22. Femtosecond nano-crystallography of membrane proteins
    Petra Fromme; Fiscal Year: 2011
    ..Membrane proteins are of extreme importance in all living cells as they catalyze vital functions like respiration, photosynthesis, transport, and cell communication...
  23. Femtosecond nano-crystallography of membrane proteins
    Petra Fromme; Fiscal Year: 2010
    ..Membrane proteins are of extreme importance in all living cells as they catalyze vital functions like respiration, photosynthesis, transport, and cell communication...
  24. PARABRACHIAL NUCLEI--ROLE IN RESPIRATORY SYSTEM DEFENSE
    Thomas Dick; Fiscal Year: 1992
    ..is a major nucleus necessary for the incorporation of sensory stimuli into the central pattern generator for respiration. Specifically, we believe that the PRG shapes the breathing pattern in response to stimulation of the nasal ..
  25. THE HIGH PRESSURE ZONE OF THE DISTAL ESOPHAGUS
    Larry Miller; Fiscal Year: 2001
    ..To achieve these specific aims the PI plans to: 1) determine the effect of respiration on the position and pressure relationships of the intrinsic LES and CD as components of the GEJHPZ...
  26. THE HIGH PRESSURE ZONE OF THE DISTAL ESOPHAGUS
    Larry Miller; Fiscal Year: 2002
    ..To achieve these specific aims the PI plans to: 1) determine the effect of respiration on the position and pressure relationships of the intrinsic LES and CD as components of the GEJHPZ...
  27. THE HIGH PRESSURE ZONE OF THE DISTAL ESOPHAGUS
    Larry Miller; Fiscal Year: 2003
    ..To achieve these specific aims the PI plans to: 1) determine the effect of respiration on the position and pressure relationships of the intrinsic LES and CD as components of the GEJHPZ...
  28. THE HIGH PRESSURE ZONE OF THE DISTAL ESOPHAGUS
    Larry Miller; Fiscal Year: 2006
    ..To achieve these specific aims the PI plans to: 1) determine the effect of respiration on the position and pressure relationships of the intrinsic LES and CD as components of the GEJHPZ...
  29. SLEEP-INDUCED APNEA: ROLE OF STATE OF CONSCIOUSNESS
    David Carley; Fiscal Year: 1990
    ..is to is to develop a system by which to study the mechanisms of interaction between state of consciousness and respiration. A related long range goal is to quantitatively evaluate the role of fluctuating state of consciousness in the ..
  30. Thoracic Insufficiency Syndrome: Validation of Animal Model for Analyzing Pathoph
    Brian D Snyder; Fiscal Year: 2010
    ..provided by applicant): Thoracic Insufficiency Syndrome (TIS) is the inability of the thorax to support normal respiration and normal postnatal lung growth...
  31. The role of the primitive choana in amniote craniofacial morphogenesis
    John Abramyan; Fiscal Year: 2012
    ..are the internal nares which connect the oral cavity to the nasal passages and are crucial for proper nasal respiration. In mammals, the choanae are covered by the secondary palate and therefore, open directly into the nasopharynx...
  32. Ninth International Conference on the Chemistry and Biology of Mineralized Tissue
    Paul Krebsbach; Fiscal Year: 2007
    ..teeth is essential for the activities of normal daily life in locomotion, mineral metabolism, organ protection, respiration, mastication, and proper nutrition and digestion, but the factors and their complex interactions responsible ..
  33. Induced Pluripotent Stem Cells in Canine Muscular Dystrophy
    Martin K Childers; Fiscal Year: 2010
    ..However, the effects of general atrophy of skeletal muscles, including those supporting respiration, may indirectly contribute to the cardiac pathology in DMD...
  34. Physiological and Emotional Reactivity to Pain after Physical and Sexual Abuse
    KARIN N WESTLUND-HIGH; Fiscal Year: 2011
    ..Recent evidence suggests controlling rate and pattern of respiration can restore an increase in HRV. Dr...
  35. Coordination of Respiration with Deglutition & Phonation in Ataxia-Telangiectasia
    Maureen Lefton Greif; Fiscal Year: 2007
    ..We will use Respirodeglutometric (RDT) instrumentation to characterize the respiration during deglutition in patients with A-T...
  36. GENETIC DETERMINANTS OF OXYGEN TOXICITY
    Valeria Culotta; Fiscal Year: 1993
    ..Oxygen radicals such as superoxide anion (O2-) are generated during respiration and through the exposure to environmental oxidants...
  37. Molecular Dissection of the Permeability Transition Pore
    Michael Forte; Fiscal Year: 2006
    ..Mitochondrial energy conservation (ATP production) requires the respiration-driven formation of a proton electrochemical potential difference (delta mu H) across the inner mitochondrial ..
  38. Molecular Dissection of the Permeability Transition Pore
    Michael Forte; Fiscal Year: 2005
    ..Mitochondrial energy conservation (ATP production) requires the respiration-driven formation of a proton electrochemical potential difference (delta mu H) across the inner mitochondrial ..
  39. Molecular Dissection of the Permeability Transition Pore
    Michael Forte; Fiscal Year: 2004
    ..Mitochondrial energy conservation (ATP production) requires the respiration-driven formation of a proton electrochemical potential difference (delta mu H) across the inner mitochondrial ..
  40. Molecular Dissection of the Permeability Transition Pore
    Michael Forte; Fiscal Year: 2007
    ..Mitochondrial energy conservation (ATP production) requires the respiration-driven formation of a proton electrochemical potential difference (delta mu H) across the inner mitochondrial ..
  41. Modulation of Mitochondrial Function by Pro-Oxidants
    LUKE IGNATIUS SZWEDA; Fiscal Year: 2010
    ..for the maintenance of cardiac energy status and function, mitochondria exhibit declines in the rate of respiration and oxidative phosphorylation during ischemia, with further age-dependent deficits evident upon reperfusion...
  42. MOLECULAR GENETICS OF RESPIRATION-DEFICIENT CELLS
    Immo Scheffler; Fiscal Year: 1990
    ..proposed constitutes a continuation of the biochemical, molecular and genetic characterization of a series of respiration-deficient mammalian cell mutants isolated by this laboratory...
  43. Cardioprotective Actions of Hydrogen Sulfide
    DAVID JOSEPH LEFER; Fiscal Year: 2010
    ..H2S attenuates leukocyte adhesion, modulates mitochondrial respiration, and inhibits both apoptosis, and oxidative stress...
  44. Modulation of Mitochondrial Function by Pro-Oxidants
    Luke Szweda; Fiscal Year: 2007
    ..for the maintenance of cardiac energy status and function, mitochondria exhibit declines in the rate of respiration and oxidative phosphorylation during ischemia, with further age-dependent deficits evident upon reperfusion...
  45. Cardioprotective Actions of Hydrogen Sulfide
    David Lefer; Fiscal Year: 2009
    ..H2S attenuates leukocyte adhesion, modulates mitochondrial respiration, and inhibits both apoptosis, and oxidative stress...
  46. Modulation of Mitochondrial Function by Pro-Oxidants
    Luke Szweda; Fiscal Year: 2009
    ..for the maintenance of cardiac energy status and function, mitochondria exhibit declines in the rate of respiration and oxidative phosphorylation during ischemia, with further age-dependent deficits evident upon reperfusion...
  47. Microxymetry Techniques for Cardiomyocyte Respiration
    Govindasamy Ilangovan; Fiscal Year: 2004
    ..The specific aims of the proposal are: (i) to study the respiration (both as such and stimulated by added stimulants) of cardiomyocytes (both cultured cells and freshly isolated ..
  48. Microxymetry Techniques for Cardiomocyte Respiration
    Govindasamy Ilangovan; Fiscal Year: 2005
    ..The specific aims of the proposal are: (i) to study the respiration (both as such and stimulated by added stimulants) of cardiomyocytes (both cultured cells and freshly isolated ..
  49. Cations and ROS in Modulating Mitochondrial Function in Normal and Ischemic Heart
    RANJAN K contact DASH; Fiscal Year: 2010
    ..binding of the cations with phosphates (ATP, ADP, PI) and substrates (TCA cycle intermediates) during transient respiration, which in turn regulate mito- chondrial function, including the rate of ROS generation...
  50. Role of Txnip in adapting fuel metabolism to nutritional state
    SIMON HUI; Fiscal Year: 2009
    ..Electron microscopy will be used to detect alterations in mitochondrial ultrastructure. Mitochondrial respiration will be measured by polarography and the defective component in the oxidative phosphorylation pathway will be ..
  51. ADENOSINE RECEPTORS AND THE PATHOPHYSIOLOGY OF SIDS
    H Zielke; Fiscal Year: 1990
    ..It is known that the adenosine agonist phenylisopropyl adenosine (PIA) causes apnea, decreased respiration, and death; furthermore, young rabbits are susceptible to death from PIA at a five-fold lower concentration ..
  52. Tilt/Recline Adjustment by Subjects with ALS using Brain Computer Interfaces
    Jane Huggins; Fiscal Year: 2009
    ..provide such people with independent control of power tilt/recline for pressure relief, comfort, and improved respiration. This experimental/development grant (R21) application will support the prototype development of a BCI to ..
  53. CONTROL OF DRUG AND ETHANOL METABOLISM
    Ronald Thurman; Fiscal Year: 1990
    ..Specifically, this goal will be achieved by studying the effect of O2 on intracellular free Ca++ and respiration of fresh plugs of tissue isolated from periportal and pericentral regions of the liver lobule...
  54. CONTROL OF DRUG AND ETHANOL METABOLISM
    Ronald Thurman; Fiscal Year: 1992
    ..Specifically, this goal will be achieved by studying the effect of O2 on intracellular free Ca++ and respiration of fresh plugs of tissue isolated from periportal and pericentral regions of the liver lobule...
  55. Sensitization to thermoradiotherapy in human xenografts
    Dennis Leeper; Fiscal Year: 2003
    ..Aim 1 will investigate inhibition of mitochondrial respiration by meta-iobenzylguanidine (MIBG) on melanoma acidification and oxygenation for sensitization to ..
  56. Novel Models to Predict Energy Expenditure and Physical Activity in Preschoolers
    Nancy F Butte; Fiscal Year: 2010
    ..adaptive regression splines (MARS) models will be developed in 88 preschool-aged children using 12-h room respiration calorimetry as the criterion method and validated in an independent sample (n=50) against12-h room respiration ..
  57. NEUROCHEMICAL CONTROL OF RESPIRATION IN SIDS
    Laurence Becker; Fiscal Year: 1990
    ..We have previously described in cases of SIDS specific changes in neural structures concerned with control of respiration (brain stem, vagus nerve) and more recently found elevated levels of catecholamines (CA), mainly dopamine in ..
  58. HEMODYNAMICS OF CARDIAC TAMPONADE
    HAROLD KLOPFENSTEIN; Fiscal Year: 1990
    ..progresses, heart size decreases and the relative sizes of the chambers fluctuate depending on the phase of respiration. Abrupt collapse of portions of the atria and later the right ventricle occur and pulsus paradoxus increases...
  59. Mitochondrial Mechanisms of Hydrogen Sulfide Induced Suspended Animation
    SHANNON MARIE BAILEY; Fiscal Year: 2010
    ..Moreover, H2S, which is known to inhibit mitochondrial respiration, has recently gained recognition as an endogenously produced cell signaling molecule capable of reducing ..
  60. Mitochondrial Mechanisms of Hydrogen Sulfide Induced Suspended Animation
    Shannon Bailey; Fiscal Year: 2009
    ..Moreover, H2S, which is known to inhibit mitochondrial respiration, has recently gained recognition as an endogenously produced cell signaling molecule capable of reducing ..
  61. STRUCTURE AND FUNCTION OF CUA IN CYTOCHROME C OXIDASE
    Craig Martin; Fiscal Year: 1992
    Cytochrome c oxidase catalyzes the 4-electron reduction of O2 to water in the final step of cellular respiration in all higher forms of life...
  62. DEVELOPMENT OF SUSTAINED ATTENTION IN INFANTS
    John Richards; Fiscal Year: 1992
    ..and 2) To study individual differences in respiratory sinus arrhythmia (RSA; variability in HR occurring at the respiration frequency) with respect to individual differences in sustained attention, premature and full-term recognition ..
  63. DEVELOPMENT OF SUSTAINED ATTENTION IN INFANTS
    John Richards; Fiscal Year: 1993
    ..and 2) To study individual differences in respiratory sinus arrhythmia (RSA; variability in HR occurring at the respiration frequency) with respect to individual differences in sustained attention, premature and full-term recognition ..
  64. PROTON COUPLING STRATEGIES IN ALKALIPHILIC BACILLUS
    TERRY KRULWICH; Fiscal Year: 1999
    ..goals of this project are to understand how extremely alkaliphilic Bacillus strains (non-halophiles) achieve respiration-coupled ATP synthesis and cytoplasmic pH regulation...
  65. PROTON COUPLING STRATEGIES IN ALKALIPHILIC BACILLUS
    TERRY KRULWICH; Fiscal Year: 2000
    ..goals of this project are to understand how extremely alkaliphilic Bacillus strains (non-halophiles) achieve respiration-coupled ATP synthesis and cytoplasmic pH regulation...
  66. INTRACELLULAR PH RESPONSES OF CENTRAL CHEMORECEPTORS
    Robert Putnam; Fiscal Year: 2004
    Increased CO2 (hypercapnia) is a major stimulus for increased respiration and blood pressure...
  67. INTRACELLULAR PH RESPONSES OF CENTRAL CHEMORECEPTORS
    Robert Putnam; Fiscal Year: 2002
    Increased CO2 (hypercapnia) is a major stimulus for increased respiration and blood pressure...
  68. PROTON COUPLING STRATEGIES IN ALKALIPHILIC BACILLUS
    TERRY KRULWICH; Fiscal Year: 2001
    ..goals of this project are to understand how extremely alkaliphilic Bacillus strains (non-halophiles) achieve respiration-coupled ATP synthesis and cytoplasmic pH regulation...
  69. Planning Grant for Genome-Wide Association Study of Craniofacial Microsomia
    JACQUELINE R contact STARR; Fiscal Year: 2010
    ..Typically affecting the jaw and ear, CFM impairs basic functions such as hearing, speech, respiration, and chewing, in addition to its aesthetic effects. It can be life-threatening due to airway compromise...
  70. Planning Grant for Genome-Wide Association Study of Craniofacial Microsomia
    JACQUELINE STARR; Fiscal Year: 2009
    ..Typically affecting the jaw and ear, CFM impairs basic functions such as hearing, speech, respiration, and chewing, in addition to its aesthetic effects. It can be life-threatening due to airway compromise...
  71. AGING, LIPID PEROXIDATION, AND CARDIAC REPERFUSION
    Luke Szweda; Fiscal Year: 2000
    ..Adapted from the Applicant's Abstract): Reperfusion of cardiac tissue results in declines in mitochondrial respiration, the severity of which increases with age...
  72. AGING, LIPID PEROXIDATION, AND CARDIAC REPERFUSION
    Luke Szweda; Fiscal Year: 2001
    ..Adapted from the Applicant's Abstract): Reperfusion of cardiac tissue results in declines in mitochondrial respiration, the severity of which increases with age...
  73. AGING, LIPID PEROXIDATION, AND CARDIAC REPERFUSION
    Luke Szweda; Fiscal Year: 1999
    ..Adapted from the Applicant's Abstract): Reperfusion of cardiac tissue results in declines in mitochondrial respiration, the severity of which increases with age...
  74. AGING, LIPID PEROXIDATION, AND CARDIAC REPERFUSION
    Luke Szweda; Fiscal Year: 2003
    ..Adapted from the Applicant's Abstract): Reperfusion of cardiac tissue results in declines in mitochondrial respiration, the severity of which increases with age...