heart rate

Summary

Summary: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.

Top Publications

  1. ncbi Beyond heart rate variability: vagal regulation of allostatic systems
    Julian F Thayer
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Ann N Y Acad Sci 1088:361-72. 2006
  2. ncbi The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors
    Julian F Thayer
    The Ohio State University, Department of Psychology, 1835 Neil Avenue, Columbus, Ohio 43210, USA
    Int J Cardiol 141:122-31. 2010
  3. ncbi Heart rate variability: origins, methods, and interpretive caveats
    G G Berntson
    Department of Psychology, Ohio State University, Columbus 43210, USA
    Psychophysiology 34:623-48. 1997
  4. ncbi Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis
    Andrew H Kemp
    School of Psychology, University of Sydney, Sydney, Australia
    Biol Psychiatry 67:1067-74. 2010
  5. doi Neural correlates of heart rate variability during emotion
    Richard D Lane
    Department of Psychiatry, University of Arizona, Tucson, AZ, USA
    Neuroimage 44:213-22. 2009
  6. pmc The polyvagal perspective
    Stephen W Porges
    University of Illinois at Chicago, Brain Body Center, Department of Psychiatry, Chicago, IL 60612, USA
    Biol Psychol 74:116-43. 2007
  7. pmc Low-frequency power of heart rate variability is not a measure of cardiac sympathetic tone but may be a measure of modulation of cardiac autonomic outflows by baroreflexes
    David S Goldstein
    Clinical Neurocardiology Section, Clinical Neurosciences Program, Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1620, USA
    Exp Physiol 96:1255-61. 2011
  8. ncbi Cardiac interbeat interval dynamics from childhood to senescence : comparison of conventional and new measures based on fractals and chaos theory
    S M Pikkujämsä
    Division of Cardiology, Department of Internal Medicine, University of Oulu, Finland
    Circulation 100:393-9. 1999
  9. ncbi Heart rate variability: a review
    U Rajendra Acharya
    Department of ECE, Ngee Ann Polytechnic, 535 Clementi Road, Singapore, Singapore 599 489
    Med Biol Eng Comput 44:1031-51. 2006
  10. ncbi A comparison of rate control and rhythm control in patients with atrial fibrillation
    D G Wyse
    AFFIRM Clinical Trial Center, Axio Research, 2601 4th Ave, Ste 200, Seattle, WA 98121, USA
    N Engl J Med 347:1825-33. 2002

Detail Information

Publications340 found, 100 shown here

  1. ncbi Beyond heart rate variability: vagal regulation of allostatic systems
    Julian F Thayer
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Ann N Y Acad Sci 1088:361-72. 2006
    ..Decreased vagal function and heart rate variability (HRV) were shown to be associated with increased fasting glucose and hemoglobin A1c levels, ..
  2. ncbi The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors
    Julian F Thayer
    The Ohio State University, Department of Psychology, 1835 Neil Avenue, Columbus, Ohio 43210, USA
    Int J Cardiol 141:122-31. 2010
    ..b>Heart rate variability (HRV) may be used to assess autonomic imbalances, diseases and mortality...
  3. ncbi Heart rate variability: origins, methods, and interpretive caveats
    G G Berntson
    Department of Psychology, Ohio State University, Columbus 43210, USA
    Psychophysiology 34:623-48. 1997
    Components of heart rate variability have attracted considerable attention in psychology and medicine and have become important dependent measures in psychophysiology and behavioral medicine...
  4. ncbi Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis
    Andrew H Kemp
    School of Psychology, University of Sydney, Sydney, Australia
    Biol Psychiatry 67:1067-74. 2010
    ..in the likelihood of cardiac events; however, studies investigating the relationship between depression and heart rate variability (HRV) have generally focused on patients with cardiovascular disease (CVD)...
  5. doi Neural correlates of heart rate variability during emotion
    Richard D Lane
    Department of Psychiatry, University of Arizona, Tucson, AZ, USA
    Neuroimage 44:213-22. 2009
    The vagal (high frequency [HF]) component of heart rate variability (HRV) predicts survival in post-myocardial infarction patients and is considered to reflect vagal antagonism of sympathetic influences...
  6. pmc The polyvagal perspective
    Stephen W Porges
    University of Illinois at Chicago, Brain Body Center, Department of Psychiatry, Chicago, IL 60612, USA
    Biol Psychol 74:116-43. 2007
    ....
  7. pmc Low-frequency power of heart rate variability is not a measure of cardiac sympathetic tone but may be a measure of modulation of cardiac autonomic outflows by baroreflexes
    David S Goldstein
    Clinical Neurocardiology Section, Clinical Neurosciences Program, Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1620, USA
    Exp Physiol 96:1255-61. 2011
    Power spectral analysis of heart rate variability has often been used to assess cardiac autonomic function; however, the relationship of low-frequency (LF) power of heart rate variability to cardiac sympathetic tone has been unclear...
  8. ncbi Cardiac interbeat interval dynamics from childhood to senescence : comparison of conventional and new measures based on fractals and chaos theory
    S M Pikkujämsä
    Division of Cardiology, Department of Internal Medicine, University of Oulu, Finland
    Circulation 100:393-9. 1999
    ..interval variability based on fractal scaling and nonlinear dynamics ("chaos theory") may give new insights into heart rate dynamics...
  9. ncbi Heart rate variability: a review
    U Rajendra Acharya
    Department of ECE, Ngee Ann Polytechnic, 535 Clementi Road, Singapore, Singapore 599 489
    Med Biol Eng Comput 44:1031-51. 2006
    b>Heart rate variability (HRV) is a reliable reflection of the many physiological factors modulating the normal rhythm of the heart...
  10. ncbi A comparison of rate control and rhythm control in patients with atrial fibrillation
    D G Wyse
    AFFIRM Clinical Trial Center, Axio Research, 2601 4th Ave, Ste 200, Seattle, WA 98121, USA
    N Engl J Med 347:1825-33. 2002
    ..In both approaches, the use of anticoagulant drugs is recommended...
  11. doi Heart rate variability, prefrontal neural function, and cognitive performance: the neurovisceral integration perspective on self-regulation, adaptation, and health
    Julian F Thayer
    Department of Psychology, The Ohio State University, 1835 Neil Avenue, Columbus, OH 43210, USA
    Ann Behav Med 37:141-53. 2009
    In the present paper, we describe a model of neurovisceral integration in which a set of neural structures involved in cognitive, affective, and autonomic regulation are related to heart rate variability (HRV) and cognitive performance.
  12. pmc Depression, comorbid anxiety disorders, and heart rate variability in physically healthy, unmedicated patients: implications for cardiovascular risk
    Andrew H Kemp
    School of Psychology, University of Sydney, Sydney, New South Wales, Australia
    PLoS ONE 7:e30777. 2012
    There is evidence that heart rate variability (HRV) is reduced in major depressive disorder (MDD), although there is debate about whether this effect is caused by medication or the disorder per se...
  13. ncbi Short-term heart rate variability strongly predicts sudden cardiac death in chronic heart failure patients
    Maria Teresa La Rovere
    Divisione di Cardiologia e Bioingegneria, Fondazione Salvatore Maugeri, IRCCS Istituto Scientifico di Montescano, Pavia, Italy
    Circulation 107:565-70. 2003
    The predictive value of heart rate variability (HRV) in chronic heart failure (CHF) has never been tested in a comprehensive multivariate model using short-term laboratory recordings designed to avoid the confounding effects of ..
  14. ncbi Heart rate variability and its relation to prefrontal cognitive function: the effects of training and detraining
    Anita Lill Hansen
    University of Bergen, Department of Psychosocial Science, Christiesgate 12, 5015 Bergen, Norway
    Eur J Appl Physiol 93:263-72. 2004
    The aim of the present study was to investigate the relationship between physical fitness, heart rate variability (HRV) and cognitive function in 37 male sailors from the Royal Norwegian Navy...
  15. doi Transcontinental and translational high-tech acupuncture research using computer-based heart rate and "Fire of Life" heart rate variability analysis
    Gerhard Litscher
    Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine, TCM Research Center Graz, Medical University of Graz, Auenbruggerplatz 29, Austria
    J Acupunct Meridian Stud 3:156-64. 2010
    ..Today, new computer-based methods (e.g., "Fire of Life" analysis) allow quantification of heart rate and heart rate variability during acupuncture...
  16. ncbi Fractal correlation properties of R-R interval dynamics and mortality in patients with depressed left ventricular function after an acute myocardial infarction
    H V Huikuri
    Division of Cardiology, Department of Medicine, University of Oulu, Finland
    Circulation 101:47-53. 2000
    ..The purpose of this study was to compare the prognostic power of new fractal and traditional measures of R-R interval variability as predictors of death after acute myocardial infarction...
  17. ncbi Physiological background of the loss of fractal heart rate dynamics
    Mikko P Tulppo
    Merikoski Rehabilitation and Research Centre, Kasarmintie 13, PO Box 404, FIN 90101 Oulu, Finland
    Circulation 112:314-9. 2005
    Altered fractal heart rate (HR) dynamics occur during various disease states, but the physiological background of abnormal fractal HR behavior is not well known...
  18. ncbi A meta-analysis of heart rate variability and neuroimaging studies: implications for heart rate variability as a marker of stress and health
    Julian F Thayer
    Department of Psychology, The Ohio State University, 1835 Neil Avenue, Columbus, OH 43210, USA
    Neurosci Biobehav Rev 36:747-56. 2012
    ..Specifically, we performed a meta-analysis of recent neuroimaging studies on the relationship between heart rate variability and regional cerebral blood flow...
  19. ncbi Cardiovascular effects of secondhand smoke: nearly as large as smoking
    Joaquin Barnoya
    Center for Tobacco Control Research and Education, Cardiovascular Research Institute, and Division of Cardiology, University of California, San Francisco 94143 1390, USA
    Circulation 111:2684-98. 2005
    ..This effect is larger than one would expect on the basis of the risks associated with active smoking and the relative doses of tobacco smoke delivered to smokers and nonsmokers...
  20. ncbi The role of vagal function in the risk for cardiovascular disease and mortality
    Julian F Thayer
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Biol Psychol 74:224-42. 2007
    ..Using a broad range of indicators of vagal function including resting heart rate, heart rate recovery, heart rate variability, and baroreflex sensitivity we show that decreased vagal function ..
  21. doi Accuracy and validity of a combined heart rate and motion sensor for the measurement of free-living physical activity energy expenditure in adults in Cameroon
    Felix K Assah
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Int J Epidemiol 40:112-20. 2011
    ..Combined heart rate (HR) and movement monitoring make it possible to objectively measure physical activity in free-living ..
  22. pmc Acute effect of a single high-fat meal on forearm blood flow, blood pressure and heart rate in healthy male Asians and Caucasians: a pilot study
    Chumjit Bui
    Department of Health Promotion and Education, School of Public Health, Loma Linda University, Loma Linda, CA, USA
    Southeast Asian J Trop Med Public Health 41:490-500. 2010
    ..These findings suggest that a single HF meal may contribute to the detrimental effects on vascular health in Asian males and raises speculation regarding the cumulative impact of a chronic HF diet in this population...
  23. ncbi Impaired exercise performance in the heat is associated with an anticipatory reduction in skeletal muscle recruitment
    Ross Tucker
    MRC UCT Bioenergetics of Exercise Research Unit, University of Cape Town, Sports Science Institute of South Africa, PO Box 115, 7725, Newlands, South Africa
    Pflugers Arch 448:422-30. 2004
    ..during self-paced exercise in the heat occurs before there is any abnormal increase in rectal temperature, heart rate or perception of effort...
  24. doi Vagal tone dominates autonomic control of mouse heart rate at thermoneutrality
    S J Swoap
    Dept of Biomedical Sciences, Florida State University, Tallahassee, FL 32306 4300, USA
    Am J Physiol Heart Circ Physiol 294:H1581-8. 2008
    It is generally accepted that cardiac sympathetic tone dominates the control of heart rate (HR) in mice...
  25. pmc Effects of cardiac autonomic dysfunction on mortality risk in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial
    Rodica Pop-Busui
    Division of Metabolism, Endocrinology and Diabetes, University of Michigan, Ann Arbor, Michigan, USA
    Diabetes Care 33:1578-84. 2010
    ....
  26. ncbi Randomized trial of rate-control versus rhythm-control in persistent atrial fibrillation: the Strategies of Treatment of Atrial Fibrillation (STAF) study
    Jorg Carlsson
    Department of Internal Medicine II, Klinikum Lippe Detmold, Röntgenstrasse 18, D 32760 Detmold, Germany
    J Am Coll Cardiol 41:1690-6. 2003
    ....
  27. ncbi Cardiovascular, electrodermal, and respiratory response patterns to fear- and sadness-inducing films
    Sylvia D Kreibig
    Department of Psychology, Swiss Center for Affective Sciences, University of Geneva, Geneva, Switzerland
    Psychophysiology 44:787-806. 2007
    Responses to fear- and sadness-inducing films were assessed using a broad range of cardiovascular (heart rate, T-wave amplitude, low- and high-frequency heart rate variability, stroke volume, preejection period, left-ventricular ejection ..
  28. ncbi Plasma leptin concentrations and cardiac autonomic nervous system in healthy subjects with different body weights
    G Paolisso
    Department of Geriatric Medicine and Metabolic Diseases II, University of Naples, Italy
    J Clin Endocrinol Metab 85:1810-4. 2000
    Previous studies have shown that leptin stimulates sympathetic nervous system; heart rate variability (HRV) is a widely used technique for assessing the sympathovagal balance at the cardiac level...
  29. ncbi An autonomic flexibility-neurovisceral integration model of anxiety and cardiac vagal tone
    Bruce H Friedman
    Department of Psychology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 0436, USA
    Biol Psychol 74:185-99. 2007
    Research on heart rate variability (HRV), cardiac vagal tone, and their relationship to anxiety is reviewed in the context of the autonomic flexibility and neurovisceral integration models of adaptive functioning...
  30. ncbi Nocturnal hypertension in mice consuming a high fructose diet
    Vera Farah
    Boonshoft School of Medicine of Wright State University, Department of Pharmacology and Toxicology, Dayton, OH 45401, USA
    Auton Neurosci 130:41-50. 2006
    To investigate the effect of fructose consumption on the light/dark pattern of blood pressure, heart rate and autonomic neural function in mice.
  31. ncbi Increased heart rate and reduced heart-rate variability are associated with subclinical inflammation in middle-aged and elderly subjects with no apparent heart disease
    Ahmad Sajadieh
    Department of Cardiology, Copenhagen University Hospital of Bispebjerg, Bispebjerg Bakke 23, Copenhagen NV 2400, Denmark
    Eur Heart J 25:363-70. 2004
    Elevation of inflammation markers, high heart rate, and reduced heart-rate variability are all strong markers of mortality in a broad spectrum of patients. The association between these markers has not been clarified thoroughly...
  32. ncbi Heart rate as a prognostic risk factor in patients with coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a subgroup analysis of a randomised controlled trial
    Kim Fox
    Royal Brompton Hospital, London, UK
    Lancet 372:817-21. 2008
    The BEAUTIFUL study assessed the morbidity and mortality benefits of the heart rate-lowering agent ivabradine...
  33. ncbi Effect of fish oil on heart rate in humans: a meta-analysis of randomized controlled trials
    Dariush Mozaffarian
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Circulation 112:1945-52. 2005
    The effect of fish oil on heart rate (HR), a major risk factor for sudden death, is not well established. We calculated this effect in a meta-analysis of randomized, double-blind, placebo-controlled trials in humans.
  34. ncbi Optimization and validation of a fully-integrated pulse sequence for modified look-locker inversion-recovery (MOLLI) T1 mapping of the heart
    Daniel R Messroghli
    Cardiac MRI Unit, Franz Volhard Klinik, Charite Campus Buch, Universitatsmedizin Berlin, HELIOS Klinikum Berlin, Germany
    J Magn Reson Imaging 26:1081-6. 2007
    ..To optimize and validate a fully-integrated version of modified Look-Locker inversion-recovery (MOLLI) for clinical single-breathhold cardiac T1 mapping...
  35. ncbi Heart-rate turbulence after ventricular premature beats as a predictor of mortality after acute myocardial infarction
    G Schmidt
    Erste Medizinische Klinik, Technischen Universitat Munchen, Germany
    Lancet 353:1390-6. 1999
    ..Thus, establishment of a new powerful method for risk prediction independent of the available stratifiers is of considerable practical value...
  36. ncbi Toward understanding respiratory sinus arrhythmia: relations to cardiac vagal tone, evolution and biobehavioral functions
    Paul Grossman
    Department of Psychosomatic and Internal Medicine, Psychophysiology Research Laboratory, University of Basel Hospital, Hebelstrasse 2, CH 4031 Basel, Switzerland
    Biol Psychol 74:263-85. 2007
    ..Finally, a recent hypothesis is expanded upon, in which RSA plays a primary role in regulation of energy exchange by means of synchronizing respiratory and cardiovascular processes during metabolic and behavioral change...
  37. pmc Insights into the mechanisms and mediators of the effects of air pollution exposure on blood pressure and vascular function in healthy humans
    Robert D Brook
    University of Michigan, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48106, USA
    Hypertension 54:659-67. 2009
    ..We aimed to determine the mechanism and air pollutant responsible. The effects of pollution on heart rate variability, blood pressure, biomarkers, and brachial flow-mediated dilatation were determined in 2 randomized, ..
  38. ncbi Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study
    Karl Swedberg
    Department of Emergency and Cardiovascular Medicine, Sahlgrenska Academy, University of Gothenburg, Goteborg, Sweden
    Lancet 376:875-85. 2010
    Chronic heart failure is associated with high mortality and morbidity. Raised resting heart rate is a risk factor for adverse outcomes...
  39. ncbi Predicting survival in heart failure case and control subjects by use of fully automated methods for deriving nonlinear and conventional indices of heart rate dynamics
    K K Ho
    Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Mass 02215 5491, USA
    Circulation 96:842-8. 1997
    Despite much recent interest in quantification of heart rate variability (HRV), the prognostic value of conventional measures of HRV and of newer indices based on nonlinear dynamics is not universally accepted.
  40. doi [Geometric index of heart rate variability in chronic obstructive pulmonary disease]
    T Dias de Carvalho
    Departamento de Fisioterapia, Universidade Estadual Paulista, Presidente Prudente, SP, Brazil
    Rev Port Pneumol 17:260-5. 2011
    It was already evidenced decreased heart rate variability (HRV) in chronic obstructive pulmonary disease (COPD) patients at rest.
  41. pmc Is heart rate variability related to memory performance in middle-aged men?
    Amit Jasvant Shah
    Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Psychosom Med 73:475-82. 2011
    b>Heart rate variability (HRV), a measure of autonomic function, has been associated with cognitive function, but studies are conflicting. Previous studies have also not controlled for familial and genetic influences.
  42. ncbi High sensitivity of human melatonin, alertness, thermoregulation, and heart rate to short wavelength light
    Christian Cajochen
    Centre for Chronobiology, Psychiatric University Clinic, Wilhelm Kleinstr 27, CH 4025 Basel, Switzerland
    J Clin Endocrinol Metab 90:1311-6. 2005
    ..Here, we report that the alerting response of light as well as its effects on thermoregulation and heart rate are also wavelength dependent...
  43. ncbi Health benefits of a pedometer-based physical activity intervention in sedentary workers
    Catherine B Chan
    Department of Biomedical Sciences, University of Prince Edward Island, Charlottetown, PE, Canada C1A 4P3
    Prev Med 39:1215-22. 2004
    ..Here, we examined the effects of a pedometer-based physical activity intervention (Prince Edward Island-First Step Program, PEI-FSP) on activity and specific health indices in 106 sedentary workers...
  44. ncbi Heart-rate profile during exercise as a predictor of sudden death
    Xavier Jouven
    Service de cardiologie, Faculté René Descartes, Universite Paris 5, Hopital Europeen Georges Pompidou, Paris, France
    N Engl J Med 352:1951-8. 2005
    Changes in heart rate during exercise and recovery from exercise are mediated by the balance between sympathetic and vagal activity...
  45. ncbi Circadian profile of cardiac autonomic nervous modulation in healthy subjects: differing effects of aging and gender on heart rate variability
    Hendrik Bonnemeier
    Medizinische Kinik II, Medizinische Universitat zu Lubeck, Lubeck, Germany
    J Cardiovasc Electrophysiol 14:791-9. 2003
    Circadian Profile of Heart Rate Variability.
  46. ncbi Dronedarone for maintenance of sinus rhythm in atrial fibrillation or flutter
    Bramah N Singh
    Cardiology Division, Veterans Affairs Greater Los Angeles Healthcare System and the David Geffen School of Medicine at UCLA, Los Angeles, CA 90073, USA
    N Engl J Med 357:987-99. 2007
    ..Dronedarone is a new antiarrhythmic agent pharmacologically related to amiodarone but developed to reduce the risk of side effects...
  47. ncbi Vagal nerve stimulation markedly improves long-term survival after chronic heart failure in rats
    Meihua Li
    Department of Cardiovascular Dynamics, Cardiovascular Center Research Institute, Suita, Japan
    Circulation 109:120-4. 2004
    Diminished cardiac vagal activity and higher heart rate predict a high mortality rate of chronic heart failure (CHF) after myocardial infarction...
  48. ncbi An advanced detrending method with application to HRV analysis
    Mika P Tarvainen
    University of Kuopio, Department of Applied Physics, Finland
    IEEE Trans Biomed Eng 49:172-5. 2002
    An advanced, simple to use, detrending method to be used before heart rate variability analysis (HRV) is presented...
  49. pmc Cardiovascular and autonomic phenotype of db/db diabetic mice
    Danielle Senador
    Boonshoft School of Medicine, Wright State University, Dayton, OH 45435, USA
    Exp Physiol 94:648-58. 2009
    ..Parameters measured were mean arterial pressure (MAP), heart rate (HR) and their variabilities...
  50. doi Claude Bernard and the heart-brain connection: further elaboration of a model of neurovisceral integration
    Julian F Thayer
    The Ohio State University, Department of Psychology, 1835 Neil Avenue, Columbus, OH 43210, USA
    Neurosci Biobehav Rev 33:81-8. 2009
    ..pathways between the amygdala and the sympathetic and parasympathetic medullary output neurons that modulate heart rate and thus heart rate variability...
  51. ncbi Bioengineering assessment of acupuncture, part 7: heart rate variability
    Gerhard Litscher
    Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine and Traditional Chinese Medicine TCM Research Center, Medical University of Graz, Graz, Austria
    Crit Rev Biomed Eng 35:183-95. 2007
    In the seventh part of this review article, preliminary research on the topic of acupuncture and heart rate variability is described. Heart rate variability (HRV) refers to the beat-to-beat alterations in heart rate...
  52. ncbi Effect of aging on gender differences in neural control of heart rate
    T B Kuo
    Institute of Neuroscience, Tzu Chi College of Medicine and Humanities, Hualien 970, Taiwan, Republic of China
    Am J Physiol 277:H2233-9. 1999
    To clarify the influence of gender on sympathetic and parasympathetic control of heart rate in middle-aged subjects and on the subsequent aging process, heart rate variability (HRV) was studied in normal populations of women (n = 598) and ..
  53. doi Dietary fish oil reduces pacemaker current and heart rate in rabbit
    Arie O Verkerk
    Heart Failure Research Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Heart Rhythm 6:1485-92. 2009
    Omega-3 polyunsaturated fatty acids (omega3-PUFAs) from fish oil (FO) reduce heart rate in humans. The mechanism underlying this cardioprotective effect of FO is unknown.
  54. ncbi Software for advanced HRV analysis
    Juha Pekka Niskanen
    Department of Applied Physics, University of Kuopio, P O Box 1627, FIN 70211 Kuopio, Finland
    Comput Methods Programs Biomed 76:73-81. 2004
    A computer program for advanced heart rate variability (HRV) analysis is presented. The program calculates all the commonly used time- and frequency-domain measures of HRV as well as the nonlinear Poincaré plot...
  55. ncbi Effects of different doses of physical activity on cardiorespiratory fitness among sedentary, overweight or obese postmenopausal women with elevated blood pressure: a randomized controlled trial
    Timothy S Church
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge 70808 4124, USA
    JAMA 297:2081-91. 2007
    ..However, a poor understanding of the physical activity-fitness dose response relation remains...
  56. pmc Fractal dynamics in physiology: alterations with disease and aging
    Ary L Goldberger
    Cardiovascular Division and Margret and H A Rey Laboratory for Nonlinear Dynamics in Medicine, Department of Medicine, Beth Israel Deaconess Medical Center Harvard Medical School, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 99:2466-72. 2002
    ..Elucidating the fractal and nonlinear mechanisms involved in physiologic control and complex signaling networks is emerging as a major challenge in the postgenomic era...
  57. ncbi Heart rate variability: measurement and clinical utility
    Robert E Kleiger
    Washington University School of Medicine, St Louis, MO, USA
    Ann Noninvasive Electrocardiol 10:88-101. 2005
    ..g., exercise or drugs. RR interval variability is useful for assessing risk of cardiovascular death or arrhythmic events, especially when combined with other tests, e.g., left ventricular ejection fraction or ventricular arrhythmias...
  58. ncbi Relationship between spectral components of cardiovascular variabilities and direct measures of muscle sympathetic nerve activity in humans
    M Pagani
    Centro Ricerche Cardiovascolari, CNR, Medicina Interna II, Ospedale L Sacco, Universita di Milano, Italy
    Circulation 95:1441-8. 1997
    ..Spectral analysis of RR interval and systolic arterial pressure variabilities may provide indirect markers of the balance between sympathetic and vagal cardiovascular control...
  59. ncbi Cardiovascular effects of human insular cortex stimulation
    S M Oppenheimer
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205
    Neurology 42:1727-32. 1992
    ..These findings may be of relevance in predicting the autonomic effects of stroke in humans and in the explanation of sudden unexpected epileptic death...
  60. ncbi Heart rate variability and myocardial infarction: systematic literature review and metanalysis
    E Buccelletti
    Department of Emergency Medicine, Catholic University of the Sacred Hearth, Rome, Italy
    Eur Rev Med Pharmacol Sci 13:299-307. 2009
    b>Heart rate, measured as beat-to-beat intervals, is not constant and varies in time. This property is known as heart rate variability (HRV) and it has been investigated in several diseases, including myocardial infarction (MI)...
  61. ncbi Insights from the study of heart rate variability
    P K Stein
    Division of Cardiology, Barnes Jewish Hospital, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Annu Rev Med 50:249-61. 1999
    Indices of heart rate variability (HRV) provide a window onto autonomic modulation of the heart...
  62. ncbi Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial
    Michael Bohm
    Universitatsklinikum des Saarlandes, Klinik fur Innere Medizin III, Homburg Saar, Germany
    Lancet 376:886-94. 2010
    Raised resting heart rate is a marker of cardiovascular risk. We postulated that heart rate is also a risk factor for cardiovascular events in heart failure...
  63. pmc RGS6/Gβ5 complex accelerates IKACh gating kinetics in atrial myocytes and modulates parasympathetic regulation of heart rate
    Ekaterina Posokhova
    Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA
    Circ Res 107:1350-4. 2010
    The parasympathetic reduction in heart rate involves the sequential activation of m2 muscarinic cholinergic receptors (m(2)Rs), pertussis toxin-sensitive (Gi/o) heterotrimeric G proteins, and the atrial potassium channel I(KACh)...
  64. ncbi Age-predicted maximal heart rate revisited
    H Tanaka
    Department of Kinesiology and Applied Physiology, University of Colorado at Boulder, 80309 0354, USA
    J Am Coll Cardiol 37:153-6. 2001
    We sought to determine a generalized equation for predicting maximal heart rate (HRmax) in healthy adults.
  65. ncbi Comparison of three mobile devices for measuring R-R intervals and heart rate variability: Polar S810i, Suunto t6 and an ambulatory ECG system
    Matthias Weippert
    Institute for Preventive Medicine, University of Rostock, St Georg Str 108, 18055 Rostock, Germany
    Eur J Appl Physiol 109:779-86. 2010
    ..available breast belt measuring devices; Polar S810i and Suunto t6, in terms of R-R interval measures and heart rate variability (HRV) indices. The second aim was to compare different HRV spectral analysis methods...
  66. ncbi Effects of highly purified eicosapentaenoic acid and docosahexaenoic acid on hemodynamics in humans
    S Grimsgaard
    Institute of Community Medicine, University of Tromsø, Norway
    Am J Clin Nutr 68:52-9. 1998
    ..parallel-design intervention study to assess possible separate effects of EPA and DHA on blood pressure, heart rate, and cardiac mechanics...
  67. ncbi Implementation and interpretation of respiratory sinus arrhythmia measures in psychosomatic medicine: practice against better evidence?
    Thomas Ritz
    Department of Psychology, Southern Methodist University, Dallas, Texas 75205, USA
    Psychosom Med 68:617-27. 2006
    Respiratory sinus arrhythmia (RSA) or high-frequency heart rate variability has been widely used as a noninvasive measure of cardiac vagal tone. However, their dependency on both respiration rate and tidal volume is largely ignored...
  68. pmc Heart rate variability predicts ESRD and CKD-related hospitalization
    Daniel J Brotman
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Am Soc Nephrol 21:1560-70. 2010
    ..We measured resting heart rate and heart rate variability in 13,241 adults (45- to 64-years old) followed for a median of 16 years in the ..
  69. pmc Traffic-related air pollution and acute changes in heart rate variability and respiratory function in urban cyclists
    Scott Weichenthal
    Air Health Sciences Division, Health Canada, Ottawa, Canada
    Environ Health Perspect 119:1373-8. 2011
    ..Few studies have examined the acute health effects of air pollution exposures experienced while cycling in traffic...
  70. ncbi Effects of omega-3 fatty acids on resting heart rate, heart rate recovery after exercise, and heart rate variability in men with healed myocardial infarctions and depressed ejection fractions
    James H O'Keefe
    Mid America Heart Institute, Saint Luke s Hospital, Kansas City, Missouri, USA
    Am J Cardiol 97:1127-30. 2006
    ..At the end of each period, heart rate (HR), HR variability, and rate of HR recovery after exercise were determined, as were effects on arterial ..
  71. ncbi Heart rate variability biofeedback as a behavioral neurocardiac intervention to enhance vagal heart rate control
    Robert P Nolan
    Behavioural Cardiology Research Unit, University Health Network and Faculty of Medicine, University of Toronto, Toronto, Canada
    Am Heart J 149:1137. 2005
    ..heart disease (CHD) who experience depressed mood or psychological stress exhibit decreased vagal control of heart rate (HR), as assessed by spectral analysis of HR variability (HRV)...
  72. doi Exercise training associated with diet improves heart rate recovery and cardiac autonomic nervous system activity in obese children
    D M Prado
    Medical School, Department of Endocrinology, University of Sao Paulo, Brazil
    Int J Sports Med 31:860-5. 2010
    ..The purpose of this study was to test the hypotheses that in obese children: 1) hypocaloric diet (D) improves both heart rate recovery at 1 min (Δ HRR1) cfter an exercise test, and cardiac autonomic nervous system activity (CANSA) in ..
  73. pmc Fractal correlation property of heart rate variability in chronic obstructive pulmonary disease
    Tatiana D Carvalho
    Departamento de Fisioterapia da Faculdade de Ciências e Tecnologia, Universidade Estadual Paulista, Presidente Prudente, Sao Paulo, Brasil
    Int J Chron Obstruct Pulmon Dis 6:23-8. 2011
    It was reported that autonomic nervous system function is altered in subjects with chronic obstructive pulmonary disease (COPD). We evaluated short- and long-term fractal exponents of heart rate variability (HRV) in COPD subjects.
  74. pmc Effect of dietary omega-3 fatty acids on the heart rate and the heart rate variability responses to myocardial ischemia or submaximal exercise
    George E Billman
    Dept of Physiology and Cell Biology, Ohio State Univ, 304 Hamilton Hall, 1645 Neil Ave, Columbus, OH 43210 1218, USA
    Am J Physiol Heart Circ Physiol 300:H2288-99. 2011
    The consumption of omega-3 polyunsaturated fatty acids (n-3 PUFAs) has been reported to decrease resting heart rate (HR) and increase heart rate variability (HRV)...
  75. ncbi Effects of VDT tasks with a bright display at night on melatonin, core temperature, heart rate, and sleepiness
    Shigekazu Higuchi
    Department of Public Health, Akita University School of Medicine, Akita 010 8543, Japan
    J Appl Physiol (1985) 94:1773-6. 2003
    ..tasks with a bright display (BD) at night on nocturnal salivary melatonin concentration, rectal temperature, heart rate, and sleepiness were examined...
  76. ncbi Effects of propranolol on recovery of heart rate variability following acute myocardial infarction and relation to outcome in the Beta-Blocker Heart Attack Trial
    Rachel Lampert
    Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut 06520, USA
    Am J Cardiol 91:137-42. 2003
    This study evaluated the effects of propranolol on recovery of heart rate variability (HRV) after acute myocardial infarction and its relation to outcome in the Beta-blocker Heart Attack Trial (BHAT)...
  77. ncbi Heart rate, oxygen uptake, and energy cost of ascending and descending the stairs
    Kong Chuan Teh
    Sports Medicine and Research Center, Singapore Sports Council, National Stadium, 15 Stadium Road, Kallang, Singapore 397718
    Med Sci Sports Exerc 34:695-9. 2002
    This study describes the heart rate and oxygen uptake responses during, and the intensity and caloric cost of, ascending and descending a public-access staircase.
  78. doi Long term vagal stimulation in patients with advanced heart failure: first experience in man
    Peter J Schwartz
    Department of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Eur J Heart Fail 10:884-91. 2008
    ..In man, VS is used in refractory epilepsy but has never been used in cardiovascular diseases. Increased sympathetic and reduced vagal activity predict increased mortality in HF...
  79. doi Heart rate variability, overnight urinary norepinephrine and C-reactive protein: evidence for the cholinergic anti-inflammatory pathway in healthy human adults
    J F Thayer
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    J Intern Med 265:439-47. 2009
    ..Therefore, the objective of this study was to assess the immunomodulatory effects of the ANS...
  80. doi Reduced serotonergic functioning changes heart rate in ADHD
    Florian Daniel Zepf
    Department of Child and Adolescent Psychiatry and Psychotherapy, Goethe University of Frankfurt am Main, Deutschordenstr, Frankfurt, Germany
    J Neural Transm 116:105-8. 2009
    Reduced mean heart rate (HR) was shown to be a biophysiological marker for aggression, which in turn was proven to be related to changed serotonergic neurotransmission...
  81. pmc Particulate air pollution, metabolic syndrome, and heart rate variability: the multi-ethnic study of atherosclerosis (MESA)
    Sung Kyun Park
    Department of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA
    Environ Health Perspect 118:1406-11. 2010
    ..5 µm in diameter (PM2.5) and cardiovascular disease (CVD). We examined the associations of PM2.5 with heart rate variability, a marker of autonomic function, and whether metabolic syndrome (MetS) modified these associations.
  82. ncbi Autonomic dysregulation in essential hypertension: insight from heart rate and arterial pressure variability
    M Pagani
    Department of Internal Medicine, University of Milano, Italy
    Auton Neurosci 90:76-82. 2001
    ..In prior studies, we reported that parameters obtained by spectral analysis of heart rate variability (HRV) might furnish useful information on autonomic normal and abnormal nervous system regulation...
  83. doi American Heart Association/American College of Cardiology Foundation/Heart Rhythm Society Scientific Statement on Noninvasive Risk Stratification Techniques for Identifying Patients at Risk for Sudden Cardiac Death. A scientific statement from the America
    Jeffrey J Goldberger
    J Am Coll Cardiol 52:1179-99. 2008
  84. ncbi Adiponectin concentrations in sera from patients with type 2 diabetes are negatively associated with sympathovagal balance as evaluated by power spectral analysis of heart rate variation
    Sadao Wakabayashi
    Department of Internal Medicine, Koshigaya Hospital, Dokkyo University School of Medicine, 2 1 50 Minami Koshigaya, Koshigaya, Saitama 343 8555, Japan
    Diabetes Care 27:2392-7. 2004
    ..whether cardiac autonomic activity, particularly sympathovagal balance as estimated by power spectral analysis (PSA) of heart rate variation (HRV), is associated with serum adiponectin concentrations in patients with type 2 diabetes.
  85. doi Effects of indoor, outdoor, and personal exposure to particulate air pollution on cardiovascular physiology and systemic mediators in seniors
    Ling Liu
    Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada K1A 0K9
    J Occup Environ Med 51:1088-98. 2009
    ..To investigate the associations between exposure to particulate air pollution and changes in cardiovascular function and plasma mediators in seniors...
  86. ncbi Heart rate dependency of pulse pressure amplification and arterial stiffness
    Ian B Wilkinson
    Clinical Pharmacology Unit, University of Edinburgh, Western General Hospital, United Kingdom
    Am J Hypertens 15:24-30. 2002
    ..The aim of the present study was to assess the effect of acute changes in heart rate on arterial stiffness and on peripheral and central pulse pressure in healthy subjects.
  87. ncbi Validity of the polar S810 heart rate monitor to measure R-R intervals at rest
    François Xavier Gamelin
    Faculty of Sport Sciences, University of Lille, Ronchin, France
    Med Sci Sports Exerc 38:887-93. 2006
    This study was conducted to compare R-R intervals and the subsequent analysis of heart rate variability (HRV) obtained from the Polar S810 heart rate monitor (HRM) (Polar Electro Oy) with an electrocardiogram (ECG) (Physiotrace, Estaris, ..
  88. ncbi Reduced heart rate multiscale entropy predicts death in critical illness: a study of physiologic complexity in 285 trauma patients
    Patrick R Norris
    Division of Trauma, Burn, and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    J Crit Care 23:399-405. 2008
    We have shown previously that reduced integer heart rate variability (HRVi) predicts death in trauma patients...
  89. ncbi Deceleration capacity of heart rate as a predictor of mortality after myocardial infarction: cohort study
    Axel Bauer
    Deutsches Herzzentrum Munchen, Klinikum rechts der Isar, Technische Universitat Munchen, Germany
    Lancet 367:1674-81. 2006
    ..variability, we used a signal-processing algorithm to separately characterise deceleration and acceleration of heart rate. We postulated that diminished deceleration-related modulation of heart rate is an important prognostic marker...
  90. ncbi Exercise capacity and mortality among men referred for exercise testing
    Jonathan Myers
    Division of Cardiovascular Medicine, Stanford University Medical Center and the Veterans Affairs Palo Alto Health Care System, Palo Alto, Calif CA 94304, USA
    N Engl J Med 346:793-801. 2002
    ..There is also uncertainty regarding the predictive power of exercise capacity relative to other clinical and exercise-test variables...
  91. doi Heart rate variability explored in the frequency domain: a tool to investigate the link between heart and behavior
    Nicola Montano
    Department of Clinical Science, Luigi Sacco Hospital, University of Milan, Milan, Italy
    Neurosci Biobehav Rev 33:71-80. 2009
    ..Spectral analysis of cardiovascular signal variability, and in particular of RR period (heart rate variability, HRV), is a widely used procedure to investigate autonomic cardiovascular control and/or target ..
  92. doi Longitudinal evidence for unfavorable effects of antidepressants on heart rate variability
    Carmilla M M Licht
    Department of Psychiatry, EMGO Institute for Health and Care Research, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Biol Psychiatry 68:861-8. 2010
    ..It was previously shown that antidepressants are associated with diminished vagal control over the heart. Longitudinal studies are needed to test the causality of this association further...
  93. doi Diesel exhaust inhalation does not affect heart rhythm or heart rate variability
    Nicholas L Mills
    Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, UK
    Heart 97:544-50. 2011
    ..This study was undertaken to determine the effect of diesel exhaust inhalation on heart rhythm and heart rate variability in healthy volunteers and patients with coronary heart disease.
  94. pmc Genome-wide association analysis identifies multiple loci related to resting heart rate
    Mark Eijgelsheim
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Hum Mol Genet 19:3885-94. 2010
    Higher resting heart rate is associated with increased cardiovascular disease and mortality risk. Though heritable factors play a substantial role in population variation, little is known about specific genetic determinants...
  95. ncbi Prediction of mortality using measures of cardiac autonomic dysfunction in the diabetic and nondiabetic population: the MONICA/KORA Augsburg Cohort Study
    Dan Ziegler
    Institute for Clinical Diabetes Research, German Diabetes Center, Leibniz Institute at the Heinrich Heine University, Dusseldorf, Germany
    Diabetes Care 31:556-61. 2008
    To evaluate whether reduced heart rate variability (HRV), prolonged corrected QT (QTc) interval, or increased QT dispersion (QTD) are predictors of mortality in the general diabetic and nondiabetic population.
  96. ncbi Basic notions of heart rate variability and its clinical applicability
    Luiz Carlos Marques Vanderlei
    Faculty of Health and Technology, FCT UNESP, Presidente Prudente, Sao Paulo, SP, Brazil
    Rev Bras Cir Cardiovasc 24:205-17. 2009
    ..Among the techniques used in its evaluation, the heart rate variability (HRV) has arising as a simple and non-invasive measure of the autonomic impulses, representing one ..
  97. doi Clinical impact of evaluation of cardiovascular control by novel methods of heart rate dynamics
    Heikki V Huikuri
    Department of Internal Medicine, Institute of Clinical Medicine, Centre of Excellence in Research, University of Oulu, Oulu 90014, Finland
    Philos Trans A Math Phys Eng Sci 367:1223-38. 2009
    b>Heart rate variability (HRV) has been conventionally analysed with time- and frequency-domain methods, which measure the overall magnitude of RR interval fluctuations around its mean value or the magnitude of fluctuations in some ..
  98. pmc Autonomic effects of controlled fine particulate exposure in young healthy adults: effect modification by ozone
    Asghar A Fakhri
    Cardiovascular Epidemiology Research Unit, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Environ Health Perspect 117:1287-92. 2009
    ..studies have assessed the impact of ambient fine particulate matter on cardiac autonomic function measured by heart rate variability (HRV), but whether these effects are modified by concomitant ozone exposure remains unknown.
  99. ncbi Point: cardiovascular variability is/is not an index of autonomic control of circulation
    Gianfranco Parati
    Department of Clinical Medicine Prevention and Applied Biotechnology University of Milano Bicocca Milan, Italy
    J Appl Physiol 101:676-8; discussion 681-2. 2006
  100. doi Increased sympathetic and decreased parasympathetic activity rather than changes in hypothalamic-pituitary-adrenal axis activity is associated with metabolic abnormalities
    Carmilla M M Licht
    Department of Psychiatry EMGO Institute, Vrije Universiteit Medical Center, AJ Ernststraat 887, 1081 HL Amsterdam, The Netherlands
    J Clin Endocrinol Metab 95:2458-66. 2010
    ..Stress is suggested to lead to metabolic dysregulations as clustered in the metabolic syndrome, but the underlying biological mechanisms are not yet well understood...
  101. ncbi Nitric oxide can increase heart rate by stimulating the hyperpolarization-activated inward current, I(f)
    P Musialek
    University Laboratory of Physiology, Oxford, UK
    Circ Res 81:60-8. 1997
    ..This may contribute to the sinus tachycardia in pathological conditions associated with an increase in myocardial production of NO...

Research Grants83

  1. FETAL REFLEX RESPONSES TO CEREBRAL HYPOPERFUSION
    Charles Wood; Fiscal Year: 1999
    ..We have demonstrated that the reflex vasomotor and heart rate responses and the reflex hormonal responses are mediated by both baroreceptor- and chemoreceptor- reflexes...
  2. The baroreflex in pregnancy: effects of adrenal and placental steroids
    Maureen Keller Wood; Fiscal Year: 2010
    ..In nonpregnant ewes cortisol increases blood pressure and heart rate, and decreases baroreflex sensitvity;adrenalectomy and total withdrawal from adrenal steroids causes decreased ..
  3. Red Blood Cell Fatty Acid Biomarkers and Cardiovascular Disease Risk
    William S Harris; Fiscal Year: 2010
    ..A decrease in heart rate, an increase in heart rate variability, and improved endothelial function have all been associated with higher ..
  4. Sleep and Brain Structure in Heart Failure
    MARY ANN WOO; Fiscal Year: 2010
    ..and changes in tissue properties and function, occurs in areas which regulate mood, memory, blood pressure, heart rate, and breathing. All of these symptoms have been linked to increased morbidity and mortality in HF...
  5. EMA Assessment of Biobehavioral Processes in Human Pregnancy
    Pathik D Wadhwa; Fiscal Year: 2010
    ..Continuous ambulatory measures of maternal heart rate, respiration and physical activity, as well as seven saliva samples over the course of each day, will be ..
  6. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..abstract_text> ..
  7. A Systems Neuroscience Approach for the Study of General Anesthesia
    Emery Brown; Fiscal Year: 2009
    ..This research will also have broad impact on the training of anesthesiologists by placing greater emphasis on systems neuroscience. ..
  8. Cardiac Physiology and Imaging Core for Mouse in Vivo
    Kirk Peterson; Fiscal Year: 2009
    ..Bore temperature is regulated using heated airflow to maintain mice at 36 - 38[unreadable]C, and heart rate is typically 480-520 beats per minute...
  9. Factors that Initiate Arrhythamias in Long QT Syndrome
    Guy Salama; Fiscal Year: 2003
    ..Sympathetic and parasympathetic modulation of heart rate, conduction of the specialized conduction system and ventricular myocardium, AP upstroke velocity, APDs, DOR, ..
  10. Factors that Initiate Arrhythamias in Long QT Syndrome
    Guy Salama; Fiscal Year: 2004
    ..Sympathetic and parasympathetic modulation of heart rate, conduction of the specialized conduction system and ventricular myocardium, AP upstroke velocity, APDs, DOR, ..
  11. Factors that Initiate Arrhythamias in Long QT Syndrome
    Guy Salama; Fiscal Year: 2005
    ..Sympathetic and parasympathetic modulation of heart rate, conduction of the specialized conduction system and ventricular myocardium, AP upstroke velocity, APDs, DOR, ..
  12. Factors that Initiate Arrhythamias in Long QT Syndrome
    Guy Salama; Fiscal Year: 2006
    ..Sympathetic and parasympathetic modulation of heart rate, conduction of the specialized conduction system and ventricular myocardium, AP upstroke velocity, APDs, DOR, ..
  13. The Prevalence of Blood Pressure Abnormalities among Veterans with SCI
    Jill Wecht; Fiscal Year: 2009
    ..Diminished autonomic cardiovascular control following SCI can result in abnormal blood pressure, blood flow and heart rate, the degree of which may or may not be related to the level and completeness of SCI (3, 4)...
  14. ECG-derived cardiopulmonary coupling biomarkers of sleep, sleep-breathing, and ca
    Robert J Thomas; Fiscal Year: 2010
    ..From the ECG, we extract heart rate variability (HRV) and ECG R-wave amplitude fluctuations associated with respiratory tidal volume changes (the ..
  15. ECG-derived cardiopulmonary coupling biomarkers of sleep, sleep-breathing, and ca
    Robert Thomas; Fiscal Year: 2009
    ..From the ECG, we extract heart rate variability (HRV) and ECG R-wave amplitude fluctuations associated with respiratory tidal volume changes (the ..
  16. PTSD Hyperarousal Symptoms Treated with Physiological Stress Management
    Walton Roth; Fiscal Year: 2009
    ..Measurements will be both physiological, using 24 hour ambulatory monitoring of skin conductance, heart rate, and physical activity during waking and sleeping, and psychological, using self-reports and clinician ..
  17. Neuroendocrine Mechanisms of Developmental Massage Therapy in Preterm Infants
    Laurie Moyer Mileur; Fiscal Year: 2009
    ..Our hypothesis will be tested by the following specific aims: #1) We will determine ANS balance, measured by heart rate variability, before, during, and after DMT;#2) We will compare the relationships between ANS balance and HPA ..
  18. Role of Chromogranin A in Metabolic Syndrome
    Sushil K Mahata; Fiscal Year: 2011
    ..We have identified that chromogranin A (Chga)-derived peptide, catestatin (CST), lowers blood pressure (BP) and heart rate (HR) by inhibiting release of catecholamines...
  19. The baroreflex in pregnancy: effects of adrenal and placental steroids
    Maureen Keller Wood; Fiscal Year: 2009
    ..In nonpregnant ewes cortisol increases blood pressure and heart rate, and decreases baroreflex sensitvity;adrenalectomy and total withdrawal from adrenal steroids causes decreased ..
  20. Autonomic consequences of brief seizures
    Mark Stewart; Fiscal Year: 2003
    ..A broader spectrum of autonomic signs, including changes in heart rate and rhythm (most often bradycardia), blood pressure (most often pressure increases), pupillary size, vasomotor ..
  21. Autonomic consequences of brief seizures
    Mark Stewart; Fiscal Year: 2004
    ..A broader spectrum of autonomic signs, including changes in heart rate and rhythm (most often bradycardia), blood pressure (most often pressure increases), pupillary size, vasomotor ..
  22. MUSCARINIC REGULATION OF CARDIAC ION CHANNELS
    Steve Sorota; Fiscal Year: 1992
    The actions of acetylcholine include a decrease in heart rate, force of contraction and conduction through the atrioventricular node...
  23. Use of Interactive Gaming for Enhanced Function after Spinal Cord Injury
    BEATRICE JENNY KIRATLI; Fiscal Year: 2011
    ..The purpose will be to evaluate muscles used, active range of motion, forces generated, heart rate, and other measurable attributes of the actions used during interactive video gaming play...
  24. Factors that Initiate Arrhythmias in lung QT Syndrome
    Guy Salama; Fiscal Year: 2004
    ..Sympathetic and parasympathetic modulation of heart rate, conduction of the specialized conduction system and ventricular myocardium, AP upstroke velocity, APDs, DOR, ..
  25. THE EFFECTS OF COCAINE ON FETAL OXYGENATION
    James Woods; Fiscal Year: 1990
    Cocaine produces increases in blood pressure and heart rate by interfering with the uptake and degradation of norepinephrine at adrenergic nerve terminals...
  26. THE EFFECTS OF COCAINE ON FETAL OXYGENATION
    James Woods; Fiscal Year: 1992
    Cocaine produces increases in blood pressure and heart rate by interfering with the uptake and degradation of norepinephrine at adrenergic nerve terminals...
  27. Lead, Cadmium,Arsenic, and cardiovascular risk in children
    Eliseo Guallar; Fiscal Year: 2010
    ..factor alpha [TNF-alpha]) in children;and 3) Exposures, cadmium, or arsenic are inversely associated with heart rate variability in children...
  28. Lead, Cadmium,Arsenic, and cardiovascular risk in children
    Eliseo Guallar; Fiscal Year: 2009
    ..factor alpha [TNF-alpha]) in children;and 3) Exposures, cadmium, or arsenic are inversely associated with heart rate variability in children...
  29. Lead, Cadmium,Arsenic, and cardiovascular risk in children
    Eliseo Guallar; Fiscal Year: 2011
    ..factor alpha [TNF-alpha]) in children;and 3) Exposures, cadmium, or arsenic are inversely associated with heart rate variability in children...
  30. ATRIAL FIBRILLATION FOLLOW UP OF RHYTHM MANAGEMENT (AFFIRM)
    EDWARD PRITCHETT; Fiscal Year: 2000
    ..leave the patient in atrial fibrillation and use digoxin, beta-blockers, or calcium channel blockers to maintain heart rate in the normal range...
  31. CENTRAL BAROREFLEX MECHANISMS OF ANESTHETIC ACTION
    MICHAEL ANDRESEN; Fiscal Year: 2000
    ..general anesthetics cause cardiovascular dysfunction in part by compromising brainstem baroreflex control of heart rate via actions in the nucleus tractus solitarius (NTS) and nucleus ambiguus (NA)...
  32. CENTRAL BAROREFLEX MECHANISMS OF ANESTHETIC ACTION
    MICHAEL ANDRESEN; Fiscal Year: 1999
    ..general anesthetics cause cardiovascular dysfunction in part by compromising brainstem baroreflex control of heart rate via actions in the nucleus tractus solitarius (NTS) and nucleus ambiguus (NA)...
  33. Transcutaneous vagus nerve stimulation in cerebral ischemia
    Ilknur Ay; Fiscal Year: 2012
    ..To determine their safety, we will monitor physiological parameters (e.g., arterial blood pressure, heart rate, heart rate variability, and respiration rate) during an immediately after stimulation and will follow-up ..
  34. AGE-RELATED CHANGES IN ALERTNESS AND VISUAL PROCESSING
    Barry Oken; Fiscal Year: 1991
    ..system activity (skin blood flow based, on laser Doppler velocimetry); parasympathetic nervous system activity (heart rate, variability)...
  35. EPIDEMIOLOGY OF LONG QT AND ASIAN SUDDEN DEATH IN SLEEP
    Ronald Munger; Fiscal Year: 1993
    ..SE Asian refugee men in Thailand with the highest known risk of SUDS we documented high-prevalences of prolonged heart rate corrected QT interval (QTc), thiamine deficiency, hypokalemia, and a positive association between poor thiamine ..
  36. Integrative Cardiovascular Control During Exercise in Hypertension
    DONAL S O apos LEARY; Fiscal Year: 2010
    ..with established hypertension abnormally large increases in sympathetic nerve activity, arterial pressure and heart rate often occur in response to exercise which precludes advisement of any strenuous physical activity due to the ..
  37. Integrative Cardiovascular Control During Exercise in Hypertension
    DONAL O LEARY; Fiscal Year: 2009
    ..with established hypertension abnormally large increases in sympathetic nerve activity, arterial pressure and heart rate often occur in response to exercise which precludes advisement of any strenuous physical activity due to the ..
  38. Amygdala Priming Mechanism Underlying the Panic Response
    SHELLEY THIELEN; Fiscal Year: 2001
    ..maximum of 6 days with a subthreshold dose of the GABAA antagonist bicuculline methiodide exhibit an increase in heart rate (> 50 beats per minute), blood pressure, respiratory rate, and anxiety- like behavior, measured using the ..
  39. Efficacy of Yoga for Treatment-Resistant PTSD
    Bessel Van der Kolk; Fiscal Year: 2009
    ..of affect and mood regulation, 4) body awareness, 5) quality of life, 6) health care utilization, 7) resting heart rate (HR) and heart rate variability (HRV). 1 Saper, R.B., Eisenberg, D.M., Davis, R.B., Culpepper, L., Phillips, R.S...
  40. Efficacy of Yoga for Treatment-Resistant PTSD
    Bessel Van der Kolk; Fiscal Year: 2010
    ..of affect and mood regulation, 4) body awareness, 5) quality of life, 6) health care utilization, 7) resting heart rate (HR) and heart rate variability (HRV). 1 Saper, R.B., Eisenberg, D.M., Davis, R.B., Culpepper, L., Phillips, R.S...
  41. Sleep and Brain Structure in Heart Failure
    Mary Woo; Fiscal Year: 2009
    ..and changes in tissue properties and function, occurs in areas which regulate mood, memory, blood pressure, heart rate, and breathing. All of these symptoms have been linked to increased morbidity and mortality in HF...
  42. Human circadian sensitivity to very short light pulses
    ELIZABETH KLERMAN; Fiscal Year: 2009
    ..include melatonin suppression (signal for seasonal reproductive changes), pupillary reflexes, and changes in heart rate, performance, and alertness...
  43. Human circadian sensitivity to very short light pulses
    Elizabeth B Klerman; Fiscal Year: 2010
    ..include melatonin suppression (signal for seasonal reproductive changes), pupillary reflexes, and changes in heart rate, performance, and alertness...
  44. The Role of Melatonin in Natural Neuroprotection
    Christine Schwartz; Fiscal Year: 2012
    ..Arousal from torpor to IBA, where body temperature increases from 5 to 37oC and heart rate explodes from 3 to 300-400 beats/min, takes an average of just 2.8 hours...
  45. The role of dynamic changes in repolarization and calcium transients in Long QT r
    Bum Rak Choi; Fiscal Year: 2010
    ..In addition, heart rate variation such as short-long-short cycle length (pause-dependent mode) or acceleration of heart rates often ..
  46. The role of dynamic changes in repolarization and calcium transients in Long QT r
    Bum Rak Choi; Fiscal Year: 2009
    ..In addition, heart rate variation such as short-long-short cycle length (pause-dependent mode) or acceleration of heart rates often ..
  47. Epigenetic Effects of Particles and Metals on Cardiac Health of an Aging Cohort
    Joel Schwartz; Fiscal Year: 2009
    ..particulate air pollution exposures are associated with specific cardiovascular outcomes, such as decreased heart rate variability, arterial stiffness, and ST-segment depression, resulting in increased death rates for CVD...
  48. MOLECULAR DISSECTION OF DOPAMINE D5 RECEPTOR ACTIONS
    David Grandy; Fiscal Year: 1993
    In addition to its importance as a neurotransmitter, dopamine has profound effects on heart rate, blood pressure, renal blood flow, sodium absorption and water retention...
  49. Epigenetic Effects of Particles and Metals on Cardiac Health of an Aging Cohort
    Joel Schwartz; Fiscal Year: 2007
    ..particulate air pollution exposures are associated with specific cardiovascular outcomes, such as decreased heart rate variability, arterial stiffness, and ST-segment depression, resulting in increased death rates for CVD...
  50. Epigenetic Effects of Particles and Metals on Cardiac Health of an Aging Cohort
    Joel Schwartz; Fiscal Year: 2006
    ..particulate air pollution exposures are associated with specific cardiovascular outcomes, such as decreased heart rate variability, arterial stiffness, and ST-segment depression, resulting in increased death rates for CVD...
  51. Physiological and Emotional Reactivity to Pain after Physical and Sexual Abuse
    KARIN N WESTLUND-HIGH; Fiscal Year: 2011
    ..Coincident physiological response changes in these chronic pain sufferers include decreased heart rate variability (HRV)...
  52. NEUROPHYSIOLOGY OF PARASYMPATHETIC CARDIAC NEURONS
    David Mendelowitz; Fiscal Year: 2012
    ..CIH impairs the baroreflex control of heart rate and diminishes cardioprotective parasympathetic activity to the heart and current research indicates these ..
  53. Red Blood Cell Fatty Acid Biomarkers and Cardiovascular Disease Risk
    William Harris; Fiscal Year: 2009
    ..A decrease in heart rate, an increase in heart rate variability, and improved endothelial function have all been associated with higher ..
  54. The Effects of Docosahexaenoic acid (DHA) on fetal cardiac outcomes
    Kathleen M Gustafson; Fiscal Year: 2010
    ..has been shown to lower triglycerides and is important to cardiovascular health and autonomic control, lowering heart rate (HR) and blood pressure and increasing heart rate variability (HRV)...
  55. Nicotine Modulation of Parasympathetic Cardiac Neurons
    David Mendelowitz; Fiscal Year: 2010
    ..Electrical or mechanical stimulation of the trigeminal nerve evokes a dramatic decrease in heart rate in animals including man, and has often been termed the `trigeminocardiac reflex'in the clinical literature,..
  56. The Effects of Docosahexaenoic acid (DHA) on fetal cardiac outcomes
    Kathleen Gustafson; Fiscal Year: 2009
    ..has been shown to lower triglycerides and is important to cardiovascular health and autonomic control, lowering heart rate (HR) and blood pressure and increasing heart rate variability (HRV)...
  57. Nicotine Modulation of Parasympathetic Cardiac Neurons
    David Mendelowitz; Fiscal Year: 2009
    ..Electrical or mechanical stimulation of the trigeminal nerve evokes a dramatic decrease in heart rate in animals including man, and has often been termed the `trigeminocardiac reflex'in the clinical literature,..
  58. PREDICTING FETAL ACIDEMIA WITH INTRAPARTUM ELECTRONIC FETAL HEART RATE MONITORING
    George A Macones; Fiscal Year: 2010
    DESCRIPTION (provided by investigator): Intrapartum electronic fetal heart rate monitoring (EFM) has become the most frequently used instrument in obstetrics in the United States, despite its classification as a "D" by the U.S...
  59. HEART RATE RECOVERY AND MORTALITY
    Michael Lauer; Fiscal Year: 2001
    Although there has been considerable attention paid to the prognostic significance of the heart rate rise during exercise, only recently has it been noted that the heart rate fall after exercise, or "heart-rate recovery," may be an even ..
  60. HEART RATE RECOVERY AND MORTALITY
    Michael Lauer; Fiscal Year: 2002
    Although there has been considerable attention paid to the prognostic significance of the heart rate rise during exercise, only recently has it been noted that the heart rate fall after exercise, or "heart-rate recovery," may be an even ..
  61. BEHAVIORAL TREATMENT OF HYPERTENSION
    James Blumenthal; Fiscal Year: 1999
    ..mechanisms responsible for BP changes, subjects underwent glucose tolerance testing, lipid analysis, studies of heart rate variability, and hemodynamic and neuroendocrine assessments...
  62. BEHAVIORAL TREATMENT OF HYPERTENSION
    James Blumenthal; Fiscal Year: 2001
    ..mechanisms responsible for BP changes, subjects underwent glucose tolerance testing, lipid analysis, studies of heart rate variability, and hemodynamic and neuroendocrine assessments...
  63. CNS MEDIATION OF CONDITIONED BRADYCARDIA
    PHILIP MC CABE; Fiscal Year: 1990
    The proposed behavioral experiments will explore the CNS pathways involved in the classical conditioning of heart rate responses in rabbits...
  64. Spontaneous Arousals in "CHIME" Infants at Risk for SIDS
    ROBERT DARNALL; Fiscal Year: 2004
    ..Subcortical arousals associated with changes in breathing, blood pressure, heart rate, and heart rate variability, may be particularly important in infants...
  65. Spontaneous Arousals in "CHIME" Infants at Risk for SIDS
    ROBERT DARNALL; Fiscal Year: 2006
    ..Subcortical arousals associated with changes in breathing, blood pressure, heart rate, and heart rate variability, may be particularly important in infants...
  66. Spontaneous Arousals in "CHIME" Infants at Risk for SIDS
    ROBERT DARNALL; Fiscal Year: 2005
    ..Subcortical arousals associated with changes in breathing, blood pressure, heart rate, and heart rate variability, may be particularly important in infants...
  67. IN VITRO MODEL OF PRECONDITIONING WITH ISOLATED MYOCYTES
    CHARLES GANOTE; Fiscal Year: 1999
    ..of ischemic preconditioning using isolated cardiac myocytes from rabbits, as an example of an animal with a fast heart rate, and from pigs, as an example of an animal with a slow heart rate...
  68. IN VITRO MODEL OF PRECONDITIONING WITH ISOLATED MYOCYTES
    CHARLES GANOTE; Fiscal Year: 2000
    ..of ischemic preconditioning using isolated cardiac myocytes from rabbits, as an example of an animal with a fast heart rate, and from pigs, as an example of an animal with a slow heart rate...
  69. Y Receptor In and Cardiovascular Function From the PHN
    John Martin; Fiscal Year: 2004
    ..by the pancreatic polypeptide neuropeptide Y (NPY) that mediates increases in mean arterial pressure (MAP) and heart rate (HR), and to explore the mechanism by which the related pancreatic polypeptide PYY, which appears to stimulate a ..
  70. IN VITRO MODEL OF PRECONDITIONING WITH ISOLATED MYOCYTES
    CHARLES GANOTE; Fiscal Year: 2001
    ..of ischemic preconditioning using isolated cardiac myocytes from rabbits, as an example of an animal with a fast heart rate, and from pigs, as an example of an animal with a slow heart rate...
  71. REGULATION OF CARDIAC RHYTHM & CONDUCTION WITH AGING
    JANICE SCHWARTZ; Fiscal Year: 1991
    ..humans and right atria from senescent Fischer 344 rats, striking and consistent age-related differences in heart rate were seen between senescent and mature humans and in tissues from senescent vs...
  72. Role of Sterols and Insulin in Cardiac Autonomic Response
    JONAS BERNARD GALPER; Fiscal Year: 2010
    ..IKACh, the hyperpolarizing K+ current that causes a hyperpolarization of the cardiac membrane and a decrease in heart rate. Sterol regulatory element binding proteins (SREBPs) are the transcription factors that regulate genes involved ..
  73. Biobehavioral Cardiovascular Health Promotion Intervention in a State Prison Syst
    Debra Moser; Fiscal Year: 2009
    ..e., Cooper Clinic Mortality Risk Index [a composite index that includes heart rate, blood pressure, diabetes, smoking status, body mass index, age, and cardio-respiratory fitness], lipid profile, ..
  74. Spiral Electrode Sensor for Intrapartum Fetal Oximetry
    JONAS POLOGE; Fiscal Year: 2003
    Fetal heart rate monitoring is intended to detect signs of fetal distress due to oxygen starvation of the fetus...
  75. ABDOMINAL FAT AND AUTONOMIC CIRCULATORY CONTROL IN HUMAN
    Kevin Davy; Fiscal Year: 2000
    ..Basal cardiac vagal modulation of heart rate is reduced and muscle sympathetic nerve activity (MSNA) is increased in obese individuals...
  76. ABDOMINAL FAT AND AUTONOMIC CIRCULATORY CONTROL IN HUMAN
    Kevin Davy; Fiscal Year: 2003
    ..Basal cardiac vagal modulation of heart rate is reduced and muscle sympathetic nerve activity (MSNA) is increased in obese individuals...
  77. Physiologic Responses to Simulated Care Activities in Older Surgical Patients
    Colleen Casey; Fiscal Year: 2007
    ..This study aims to evaluate the utility of using the ActiHeart(tm), a type of actigraph that measures motion and heart rate simultaneously, to measure simulated clinical care activities with older adults prior to their hospitalization ..
  78. ABDOMINAL FAT AND AUTONOMIC CIRCULATORY CONTROL IN HUMAN
    Kevin Davy; Fiscal Year: 2002
    ..Basal cardiac vagal modulation of heart rate is reduced and muscle sympathetic nerve activity (MSNA) is increased in obese individuals...
  79. ABDOMINAL FAT AND AUTONOMIC CIRCULATORY CONTROL IN HUMAN
    Kevin Davy; Fiscal Year: 2001
    ..Basal cardiac vagal modulation of heart rate is reduced and muscle sympathetic nerve activity (MSNA) is increased in obese individuals...