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| heart rateSummarySummary: The number of times the HEART VENTRICLES contract per unit of time, usually per minute. Top Publications
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Publications
The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factorsJulian F Thayer
The Ohio State University, Department of Psychology, 1835 Neil Avenue, Columbus, Ohio 43210, USA
Int J Cardiol 141:122-31. 2010..b>Heart rate variability (HRV) may be used to assess autonomic imbalances, diseases and mortality...
Cardiac interbeat interval dynamics from childhood to senescence : comparison of conventional and new measures based on fractals and chaos theoryS M Pikkujämsä
Division of Cardiology, Department of Internal Medicine, University of Oulu, Finland
Circulation 100:393-9. 1999..based on fractal scaling and nonlinear dynamics ("chaos theory") may give new insights into heart rate dynamics...
A comparison of rate control and rhythm control in patients with atrial fibrillationD G Wyse
AFFIRM Clinical Trial Center, Axio Research, 2601 4th Ave, Ste. 200, Seattle, WA 98121, USA
N Engl J Med 347:1825-33. 2002..Anticoagulation should be continued in this group of high-risk patients...
Fractal correlation properties of R-R interval dynamics and mortality in patients with depressed left ventricular function after an acute myocardial infarctionH V Huikuri
Division of Cardiology, Department of Medicine, University of Oulu, Finland
Circulation 101:47-53. 2000..The purpose of this study was to compare the prognostic power of new fractal and traditional measures of R-R interval variability as predictors of death after acute myocardial infarction...
Beyond heart rate variability: vagal regulation of allostatic systemsJulian F Thayer
Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
Ann N Y Acad Sci 1088:361-72. 2006..Decreased vagal function and heart rate variability (HRV) were shown to be associated with increased fasting glucose and hemoglobin A1c levels, ..
Physiological background of the loss of fractal heart rate dynamicsMikko P Tulppo
Merikoski Rehabilitation and Research Centre, Kasarmintie 13, PO Box 404, FIN 90101 Oulu, Finland
Circulation 112:314-9. 2005Altered fractal heart rate (HR) dynamics occur during various disease states, but the physiological background of abnormal fractal HR behavior is not well known...
Transcontinental and translational high-tech acupuncture research using computer-based heart rate and "Fire of Life" heart rate variability analysisGerhard Litscher
Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine, TCM Research Center Graz, Medical University of Graz, Auenbruggerplatz 29, Austria
J Acupunct Meridian Stud 3:156-64. 2010..Today, new computer-based methods (e.g., "Fire of Life" analysis) allow quantification of heart rate and heart rate variability during acupuncture...
Nocturnal hypertension in mice consuming a high fructose dietVera Farah
Boonshoft School of Medicine of Wright State University, Department of Pharmacology and Toxicology, Dayton, OH 45401, USA
Auton Neurosci 130:41-50. 2006OBJECTIVE: To investigate the effect of fructose consumption on the light/dark pattern of blood pressure, heart rate and autonomic neural function in mice...
Heart rate variability: a reviewU Rajendra Acharya
Department of ECE, Ngee Ann Polytechnic, 535 Clementi Road, Singapore, Singapore 599 489
Med Biol Eng Comput 44:1031-51. 2006b>Heart rate variability (HRV) is a reliable reflection of the many physiological factors modulating the normal rhythm of the heart...
Randomized trial of rate-control versus rhythm-control in persistent atrial fibrillation: the Strategies of Treatment of Atrial Fibrillation (STAF) studyJorg Carlsson
Department of Internal Medicine II, Klinikum Lippe Detmold, Röntgenstrasse 18, D 32760 Detmold, Germany
J Am Coll Cardiol 41:1690-6. 2003....
Plasma leptin concentrations and cardiac autonomic nervous system in healthy subjects with different body weightsG Paolisso
Department of Geriatric Medicine and Metabolic Diseases II, University of Naples, Italy
J Clin Endocrinol Metab 85:1810-4. 2000Previous studies have shown that leptin stimulates sympathetic nervous system; heart rate variability (HRV) is a widely used technique for assessing the sympathovagal balance at the cardiac level...
An autonomic flexibility-neurovisceral integration model of anxiety and cardiac vagal toneBruce H Friedman
Department of Psychology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 0436, USA
Biol Psychol 74:185-99. 2007Research on heart rate variability (HRV), cardiac vagal tone, and their relationship to anxiety is reviewed in the context of the autonomic flexibility and neurovisceral integration models of adaptive functioning...
Cardiovascular, electrodermal, and respiratory response patterns to fear- and sadness-inducing filmsSylvia D Kreibig
Department of Psychology, Swiss Center for Affective Sciences, University of Geneva, Geneva, Switzerland
Psychophysiology 44:787-806. 2007Responses to fear- and sadness-inducing films were assessed using a broad range of cardiovascular (heart rate, T-wave amplitude, low- and high-frequency heart rate variability, stroke volume, preejection period, left-ventricular ejection ..
Effects of cardiac autonomic dysfunction on mortality risk in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trialRodica Pop-Busui
Division of Metabolism, Endocrinology and Diabetes, University of Michigan, Ann Arbor, Michigan, USA
Diabetes Care 33:1578-84. 2010....
Heart-rate turbulence after ventricular premature beats as a predictor of mortality after acute myocardial infarctionG Schmidt
Erste Medizinische Klinik, Technischen Universitat Munchen, Germany
Lancet 353:1390-6. 1999..Thus, establishment of a new powerful method for risk prediction independent of the available stratifiers is of considerable practical value...
Predicting survival in heart failure case and control subjects by use of fully automated methods for deriving nonlinear and conventional indices of heart rate dynamicsK K Ho
Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Mass 02215 5491, USA
Circulation 96:842-8. 1997Despite much recent interest in quantification of heart rate variability (HRV), the prognostic value of conventional measures of HRV and of newer indices based on nonlinear dynamics is not universally accepted.
Short-term heart rate variability strongly predicts sudden cardiac death in chronic heart failure patientsMaria Teresa La Rovere
Divisione di Cardiologia e Bioingegneria, Fondazione Salvatore Maugeri, IRCCS Istituto Scientifico di Montescano, Pavia, Italy
Circulation 107:565-70. 2003The predictive value of heart rate variability (HRV) in chronic heart failure (CHF) has never been tested in a comprehensive multivariate model using short-term laboratory recordings designed to avoid the confounding effects of ..
Heart-rate profile during exercise as a predictor of sudden deathXavier Jouven
Service de cardiologie, Faculté René Descartes, Universite Paris 5, Hopital Europeen Georges Pompidou, Paris, France
N Engl J Med 352:1951-8. 2005Changes in heart rate during exercise and recovery from exercise are mediated by the balance between sympathetic and vagal activity...
Toward understanding respiratory sinus arrhythmia: relations to cardiac vagal tone, evolution and biobehavioral functionsPaul Grossman
Department of Psychosomatic and Internal Medicine, Psychophysiology Research Laboratory, University of Basel Hospital, Hebelstrasse 2, CH 4031 Basel, Switzerland
Biol Psychol 74:263-85. 2007..Finally, a recent hypothesis is expanded upon, in which RSA plays a primary role in regulation of energy exchange by means of synchronizing respiratory and cardiovascular processes during metabolic and behavioral change...
Dronedarone for maintenance of sinus rhythm in atrial fibrillation or flutterBramah N Singh
Cardiology Division, Veterans Affairs Greater Los Angeles Healthcare System and the David Geffen School of Medicine at UCLA, Los Angeles, CA 90073, USA
N Engl J Med 357:987-99. 2007..Dronedarone is a new antiarrhythmic agent pharmacologically related to amiodarone but developed to reduce the risk of side effects...
Heart rate variability, prefrontal neural function, and cognitive performance: the neurovisceral integration perspective on self-regulation, adaptation, and healthJulian F Thayer
Department of Psychology, The Ohio State University, 1835 Neil Avenue, Columbus, OH 43210, USA
Ann Behav Med 37:141-53. 2009In the present paper, we describe a model of neurovisceral integration in which a set of neural structures involved in cognitive, affective, and autonomic regulation are related to heart rate variability (HRV) and cognitive performance.
Circadian profile of cardiac autonomic nervous modulation in healthy subjects: differing effects of aging and gender on heart rate variabilityHendrik Bonnemeier
Medizinische Kinik II, Medizinische Universitat zu Lubeck, Lubeck, Germany
J Cardiovasc Electrophysiol 14:791-9. 2003Circadian Profile of Heart Rate Variability.
Heart rate variability: origins, methods, and interpretive caveatsG G Berntson
Department of Psychology, Ohio State University, Columbus 43210, USA
Psychophysiology 34:623-48. 1997Components of heart rate variability have attracted considerable attention in psychology and medicine and have become important dependent measures in psychophysiology and behavioral medicine...
Effects of different doses of physical activity on cardiorespiratory fitness among sedentary, overweight or obese postmenopausal women with elevated blood pressure: a randomized controlled trialTimothy S Church
Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge 70808 4124, USA
JAMA 297:2081-91. 2007..However, a poor understanding of the physical activity-fitness dose response relation remains...
Software for advanced HRV analysisJuha-Pekka Niskanen
Department of Applied Physics, University of Kuopio, P.O.Box 1627, FIN 70211 Kuopio, Finland
Comput Methods Programs Biomed 76:73-81. 2004A computer program for advanced heart rate variability (HRV) analysis is presented. The program calculates all the commonly used time- and frequency-domain measures of HRV as well as the nonlinear Poincaré plot...
Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trialMichael Bohm
Universitatsklinikum des Saarlandes, Klinik fur Innere Medizin III, Homburg Saar, Germany
Lancet 376:886-94. 2010Raised resting heart rate is a marker of cardiovascular risk. We postulated that heart rate is also a risk factor for cardiovascular events in heart failure...
Bioengineering assessment of acupuncture, part 7: heart rate variabilityGerhard Litscher
Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine and Traditional Chinese Medicine TCM Research Center, Medical University of Graz, Graz, Austria
Crit Rev Biomed Eng 35:183-95. 2007In the seventh part of this review article, preliminary research on the topic of acupuncture and heart rate variability is described. Heart rate variability (HRV) refers to the beat-to-beat alterations in heart rate...
RGS6/Gβ5 complex accelerates IKACh gating kinetics in atrial myocytes and modulates parasympathetic regulation of heart rateEkaterina Posokhova
Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA
Circ Res 107:1350-4. 2010The parasympathetic reduction in heart rate involves the sequential activation of m2 muscarinic cholinergic receptors (m(2)Rs), pertussis toxin-sensitive (Gi/o) heterotrimeric G proteins, and the atrial potassium channel I(KACh)...
Autonomic dysregulation in essential hypertension: insight from heart rate and arterial pressure variabilityM Pagani
Department of Internal Medicine, University of Milano, Italy
Auton Neurosci 90:76-82. 2001..In prior studies, we reported that parameters obtained by spectral analysis of heart rate variability (HRV) might furnish useful information on autonomic normal and abnormal nervous system regulation...
American Heart Association/American College of Cardiology Foundation/Heart Rhythm Society Scientific Statement on Noninvasive Risk Stratification Techniques for Identifying Patients at Risk for Sudden Cardiac Death. A scientific statement from the AmericaJeffrey J Goldberger
J Am Coll Cardiol 52:1179-99. 2008
Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysisAndrew H Kemp
School of Psychology, University of Sydney, Sydney, Australia
Biol Psychiatry 67:1067-74. 2010..in the likelihood of cardiac events; however, studies investigating the relationship between depression and heart rate variability (HRV) have generally focused on patients with cardiovascular disease (CVD)...
Effects of indoor, outdoor, and personal exposure to particulate air pollution on cardiovascular physiology and systemic mediators in seniorsLing Liu
Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada K1A 0K9
J Occup Environ Med 51:1088-98. 2009..To investigate the associations between exposure to particulate air pollution and changes in cardiovascular function and plasma mediators in seniors...
Heart rate dependency of pulse pressure amplification and arterial stiffnessIan B Wilkinson
Clinical Pharmacology Unit, University of Edinburgh, Western General Hospital, United Kingdom
Am J Hypertens 15:24-30. 2002..The aim of the present study was to assess the effect of acute changes in heart rate on arterial stiffness and on peripheral and central pulse pressure in healthy subjects.
Insights from the study of heart rate variabilityP K Stein
Division of Cardiology, Barnes Jewish Hospital, Washington University School of Medicine, St Louis, Missouri 63110, USA
Annu Rev Med 50:249-61. 1999Indices of heart rate variability (HRV) provide a window onto autonomic modulation of the heart...
Adiponectin concentrations in sera from patients with type 2 diabetes are negatively associated with sympathovagal balance as evaluated by power spectral analysis of heart rate variationSadao Wakabayashi
Department of Internal Medicine, Koshigaya Hospital, Dokkyo University School of Medicine, 2-1-50 Minami-Koshigaya, Koshigaya, Saitama 343-8555, Japan
Diabetes Care 27:2392-7. 2004..cardiac autonomic activity, particularly sympathovagal balance as estimated by power spectral analysis (PSA) of heart rate variation (HRV), is associated with serum adiponectin concentrations in patients with type 2 diabetes...
Particulate air pollution, metabolic syndrome, and heart rate variability: the multi-ethnic study of atherosclerosis (MESA)Sung Kyun Park
Department of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA
Environ Health Perspect 118:1406-11. 2010..5 µm in diameter (PM2.5) and cardiovascular disease (CVD). We examined the associations of PM2.5 with heart rate variability, a marker of autonomic function, and whether metabolic syndrome (MetS) modified these associations.
Reduced heart rate multiscale entropy predicts death in critical illness: a study of physiologic complexity in 285 trauma patientsPatrick R Norris
Division of Trauma, Burn, and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, TN 37232, USA
J Crit Care 23:399-405. 2008We have shown previously that reduced integer heart rate variability (HRVi) predicts death in trauma patients...
Validity of the polar S810 heart rate monitor to measure R-R intervals at restFrançois Xavier Gamelin
Faculty of Sport Sciences, University of Lille, Ronchin, France
Med Sci Sports Exerc 38:887-93. 2006This study was conducted to compare R-R intervals and the subsequent analysis of heart rate variability (HRV) obtained from the Polar S810 heart rate monitor (HRM) (Polar Electro Oy) with an electrocardiogram (ECG) (Physiotrace, Estaris, ..
Deceleration capacity of heart rate as a predictor of mortality after myocardial infarction: cohort studyAxel Bauer
, Klinikum rechts der Isar, , Germany
Lancet 367:1674-81. 2006..variability, we used a signal-processing algorithm to separately characterise deceleration and acceleration of heart rate. We postulated that diminished deceleration-related modulation of heart rate is an important prognostic marker...
The role of vagal function in the risk for cardiovascular disease and mortalityJulian F Thayer
Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
Biol Psychol 74:224-42. 2007..Using a broad range of indicators of vagal function including resting heart rate, heart rate recovery, heart rate variability, and baroreflex sensitivity we show that decreased vagal function ..
Age-predicted maximal heart rate revisitedH Tanaka
Department of Kinesiology and Applied Physiology, University of Colorado at Boulder, 80309 0354, USA
J Am Coll Cardiol 37:153-6. 2001We sought to determine a generalized equation for predicting maximal heart rate (HRmax) in healthy adults.
Fractal dynamics in physiology: alterations with disease and agingAry L Goldberger
Cardiovascular Division and Margret and H A Rey Laboratory for Nonlinear Dynamics in Medicine, Department of Medicine, Beth Israel Deaconess Medical Center Harvard Medical School, Boston, MA 02215, USA
Proc Natl Acad Sci U S A 99:2466-72. 2002..Elucidating the fractal and nonlinear mechanisms involved in physiologic control and complex signaling networks is emerging as a major challenge in the postgenomic era...
Exercise capacity and mortality among men referred for exercise testingJonathan Myers
Division of Cardiovascular Medicine, Stanford University Medical Center and the Veterans Affairs Palo Alto Health Care System, Palo Alto, Calif CA 94304, USA
N Engl J Med 346:793-801. 2002..There is also uncertainty regarding the predictive power of exercise capacity relative to other clinical and exercise-test variables...
Heart rate variability explored in the frequency domain: a tool to investigate the link between heart and behaviorNicola Montano
Department of Clinical Science, Luigi Sacco Hospital, University of Milan, Milan, Italy
Neurosci Biobehav Rev 33:71-80. 2009..Spectral analysis of cardiovascular signal variability, and in particular of RR period (heart rate variability, HRV), is a widely used procedure to investigate autonomic cardiovascular control and/or target ..
Autonomic effects of controlled fine particulate exposure in young healthy adults: effect modification by ozoneAsghar A Fakhri
Cardiovascular Epidemiology Research Unit, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
Environ Health Perspect 117:1287-92. 2009..studies have assessed the impact of ambient fine particulate matter on cardiac autonomic function measured by heart rate variability (HRV), but whether these effects are modified by concomitant ozone exposure remains unknown.
Basic notions of heart rate variability and its clinical applicabilityLuiz Carlos Marques Vanderlei
Faculty of Health and Technology, FCT UNESP, Presidente Prudente, Sao Paulo, SP, Brazil
Rev Bras Cir Cardiovasc 24:205-17. 2009..Among the techniques used in its evaluation, the heart rate variability (HRV) has arising as a simple and non-invasive measure of the autonomic impulses, representing one ..
Diesel exhaust inhalation does not affect heart rhythm or heart rate variabilityNicholas L Mills
Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, UK
Heart 97:544-50. 2011..This study was undertaken to determine the effect of diesel exhaust inhalation on heart rhythm and heart rate variability in healthy volunteers and patients with coronary heart disease.
Clinical impact of evaluation of cardiovascular control by novel methods of heart rate dynamicsHeikki V Huikuri
Department of Internal Medicine, Institute of Clinical Medicine, Centre of Excellence in Research, University of Oulu, Oulu 90014, Finland
Philos Trans A Math Phys Eng Sci 367:1223-38. 2009b>Heart rate variability (HRV) has been conventionally analysed with time- and frequency-domain methods, which measure the overall magnitude of RR interval fluctuations around its mean value or the magnitude of fluctuations in some ..
Genome-wide association analysis identifies multiple loci related to resting heart rateMark Eijgelsheim
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
Hum Mol Genet 19:3885-94. 2010Higher resting heart rate is associated with increased cardiovascular disease and mortality risk. Though heritable factors play a substantial role in population variation, little is known about specific genetic determinants...
Longitudinal evidence for unfavorable effects of antidepressants on heart rate variabilityCarmilla M M Licht
Department of Psychiatry, EMGO Institute for Health and Care Research, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
Biol Psychiatry 68:861-8. 2010..It was previously shown that antidepressants are associated with diminished vagal control over the heart. Longitudinal studies are needed to test the causality of this association further...
Effect of dietary omega-3 fatty acids on the heart rate and the heart rate variability responses to myocardial ischemia or submaximal exerciseGeorge E Billman
Dept of Physiology and Cell Biology, Ohio State Univ, 304 Hamilton Hall, 1645 Neil Ave, Columbus, OH 43210 1218, USA
Am J Physiol Heart Circ Physiol 300:H2288-99. 2011The consumption of omega-3 polyunsaturated fatty acids (n-3 PUFAs) has been reported to decrease resting heart rate (HR) and increase heart rate variability (HRV)...
Prediction of mortality using measures of cardiac autonomic dysfunction in the diabetic and nondiabetic population: the MONICA/KORA Augsburg Cohort StudyDan Ziegler
Institute for Clinical Diabetes Research, German Diabetes Center, Leibniz Institute at the Heinrich Heine University, Dusseldorf, Germany
Diabetes Care 31:556-61. 2008To evaluate whether reduced heart rate variability (HRV), prolonged corrected QT (QTc) interval, or increased QT dispersion (QTD) are predictors of mortality in the general diabetic and nondiabetic population.
Point: cardiovascular variability is/is not an index of autonomic control of circulationGianfranco Parati
Department of Clinical Medicine Prevention and Applied Biotechnology University of Milano-Bicocca Milan, Italy
J Appl Physiol 101:676-8; discussion 681-2. 2006
Increased sympathetic and decreased parasympathetic activity rather than changes in hypothalamic-pituitary-adrenal axis activity is associated with metabolic abnormalitiesCarmilla M M Licht
Department of Psychiatry EMGO Institute, Vrije Universiteit Medical Center, AJ Ernststraat 887, 1081 HL Amsterdam, The Netherlands
J Clin Endocrinol Metab 95:2458-66. 2010..Stress is suggested to lead to metabolic dysregulations as clustered in the metabolic syndrome, but the underlying biological mechanisms are not yet well understood...
Relationship between major depression and heart rate variability. Clinical consequences and implications for antidepressive treatmentMarcus W Agelink
Department of Biological Psychiatry and Neuroscience, Evangl Clinics Gelsenkirchen, Ruhr-University of Bochum, Munckelstr. 27, D-45879, Gelsenkirchen, Germany
Psychiatry Res 113:139-49. 2002..Standardized tests of heart rate variability (HRV) allow a quantitative estimation of autonomic nervous system function...
Cardiovascular effects of human insular cortex stimulationS M Oppenheimer
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205
Neurology 42:1727-32. 1992..These findings may be of relevance in predicting the autonomic effects of stroke in humans and in the explanation of sudden unexpected epileptic death...
Hypothalamic arcuate nucleus mediates the sympathetic and arterial pressure responses to leptinKamal Rahmouni
Center on Functional Genomics of Hypertension, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
Hypertension 49:647-52. 2007..These results also suggest that the cardiovascular effects of leptin might be evoked by the action of this hormone in the arcuate nucleus of the hypothalamus...
Progression of large artery structural and functional alterations in Type I diabetesC Giannattasio
Internal Medicine, , S.Gerardo Hospital, Monza, Milano, Italy
Diabetologia 44:203-8. 2001..CONCLUSION/INTERPRETATION: The early reduction in arterial distensibility and increase in arterial wall thickness characterizing uncomplicated normotensive Type I diabetes patients shows a measurable worsening over the short term...
How accurately can we estimate energetic costs in a marine top predator, the king penguin?Lewis G Halsey
Centre for Ornithology, School of Biosciences, University of Birmingham, Edgbaston B15 2TT, UK
Zoology (Jena) 110:81-92. 2007..Energy consumption has been estimated for many marine species using the heart rate-rate of oxygen consumption (f(H) - V(O2)) technique, and the technique has been applied successfully to answer ..
Periodic variation in R-R intervals and cardiovascular autonomic regulation in young adult Syrian hamstersH Mongue-Din
Institut de Myologie INSERM, Groupe Hospitalier Pitie Salpetriere, Paris, France
Am J Physiol Regul Integr Comp Physiol 296:R610-7. 2009..However, little is known about heart rate variability (HRV) in this species...
Nitric oxide can increase heart rate by stimulating the hyperpolarization-activated inward current, I(f)P Musialek
University Laboratory of Physiology, Oxford, UK
Circ Res 81:60-8. 1997..This may contribute to the sinus tachycardia in pathological conditions associated with an increase in myocardial production of NO...
Circadian control of mouse heart rate and blood pressure by the suprachiasmatic nuclei: behavioral effects are more significant than direct outputsW John Sheward
Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom
PLoS ONE 5:e9783. 2010..The aim of this study was to assess the influence of the suprachiasmatic nucleus (SCN) circadian clock on cardiovascular function...
Oral clonidine premedication preserves heart rate variability for patients undergoing larparoscopic cholecystectomyH-P Yu
Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Department of Anesthesiology, Veterans General Hospital-Taipei, Taipei, Taiwan
Acta Anaesthesiol Scand 47:185-90. 2003..Analysis of heart rate variability was used to quantify the control of heart rate at baseline, and during the pneumoperitoneum and ..
Stretch-induced changes in heart rate and rhythm: clinical observations, experiments and mathematical modelsP Kohl
University Laboratory of Physiology, Oxford, UK
Prog Biophys Mol Biol 71:91-138. 1999..MEF is thought to be involved in the adjustment of heart rate to changes in mechanical load and would help to explain the precise beat-to-beat regulation of cardiac ..
Measurement of heart rate variability by methods based on nonlinear dynamicsHeikki V Huikuri
Division of Cardiology, Department of Internal Medicine, University of Oulu, Finland
J Electrocardiol 36:95-9. 2003b>Heart rate (HR) variability has been conventionally analyzed with time and frequency domain methods, which measure the overall magnitude of R-R interval fluctuations around its mean value or the magnitude of fluctuations in some ..
Short-term fasting-induced autonomic activation and changes in catecholamine levels are not mediated by changes in leptin levels in healthy humansJean L Chan
Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Clin Endocrinol (Oxf) 66:49-57. 2007..We evaluated whether inducing hypoleptinaemia (with and without administration of leptin at replacement doses) for 3 days would influence catecholamine levels and sympathetic and parasympathetic activity in healthy humans...
Cardiovascular autonomic dysregulation and fatigue in multiple sclerosisS Merkelbach
Department of Neurology, University Hospital, Homburg/Saar, Germany
Mult Scler 7:320-6. 2001..Thus, autonomic disturbances might contribute to fatigue symptoms in a MS subgroup, but the overall influence of the autonomic cardiovascular regulation towards fatigue experience seems to be of minor relevance...
Heart rate multiscale entropy at three hours predicts hospital mortality in 3,154 trauma patientsPatrick R Norris
Division of Trauma, Burn, and Surgical Critical Care, Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA
Shock 30:17-22. 2008..Previously, we have shown integer heart rate (HR) multiscale entropy (MSE), an indicator of complexity, predicts death based on long duration (12 h) and ..
Heart rate and blood pressure responses to tobacco smoking among African-American adolescentsEric T Moolchan
National Institute on Drug Abuse, Intramural Research Program National Institutes of Health, U S Department of Health and Human Services, S 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
J Natl Med Assoc 96:767-71. 2004..Blood pressure, heart rate, and exhaled carbon monoxide (CO) concentrations were measured before and after smoking; mean puff volume (mL), ..
Decrease in the heart rate complexity prior to the onset of atrial fibrillationVolkan Tuzcu
Department of Pediatrics, Division of Cardiology, Arkansas Children s Hospital, University of Arkansas for Medical Sciences, 800 Marshall Street, Slot 512 3, Little Rock, AR 72202, USA
Europace 8:398-402. 2006To assess heart rate complexity changes prior to the onset of atrial fibrillation (AF) using sample entropy. It has been proposed that the autonomic nervous system might have a role in the initiation of AF.
Low dose mercury and heart rate variability among community residents nearby to an industrial complex in KoreaSinye Lim
Department of Occupational and Environmental Medicine, College of Medicine, Kyunghee University, Seoul, Republic of Korea
Neurotoxicology 31:10-6. 2010..In this cross-sectional study, the hair mercury was analyzed in relation to the cardiac autonomic activity among community residents nearby to an industrial complex in Korea...
Diabetic hypertensive leptin receptor-deficient db/db mice develop cardioregulatory autonomic dysfunctionAndrey C da Costa Goncalves
Max Delbruck Center for Molecular Medicine, Robert Rossle Strasse 10, 13125 Berlin, Germany
Hypertension 53:387-92. 2009..The resting period BP (117+/-3 versus 108+/-1.0 mm Hg) and heart rate (HR; 488+/-12 versus 436+/-8 bpm) were higher in db/db mice compared with db/+ mice...
Brain and autonomic association accompanying stochastic decision-makingHideki Ohira
Department of Psychology, Nagoya University, Furo, Chikusa, Nagoya, Japan
Neuroimage 49:1024-37. 2010..These findings suggest that the prefrontal-striatal network provides a neural basis for decision-making and modulation over the peripheral autonomic activity accompanying decision-making...
Limbic dysregulation is associated with lowered heart rate variability and increased trait anxiety in healthy adultsLilianne R Mujica-Parodi
Department of Biomedical Engineering, Stony Brook University, Stony Brook, New York 11794 8181, USA
Hum Brain Mapp 30:47-58. 2009....
Insulin regulation of heart function in aging fruit fliesRobert J Wessells
The Burnham Institute, Center for Neuroscience and Aging, 10901 Torrey Pines Road, La Jolla, California 92037, USA
Nat Genet 36:1275-81. 2004..progressive changes of heart function in aging fruit flies: from one to seven weeks of a fly's age, the resting heart rate decreases and the rate of stress-induced heart failure increases...
A comparison of rate control and rhythm control in patients with recurrent persistent atrial fibrillationIsabelle C Van Gelder
Department of Cardiology, Thoraxcenter, University Hospital, Groningen, The Netherlands
N Engl J Med 347:1834-40. 2002..We hypothesized that ventricular rate control is not inferior to the maintenance of sinus rhythm for the treatment of atrial fibrillation...
Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome: a pilot studyArnt Erik Tjønna
Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway
Circulation 118:346-54. 2008..We compared moderate and high exercise intensity with regard to variables associated with cardiovascular function and prognosis in patients with the metabolic syndrome...
From mental power to muscle power--gaining strength by using the mindVinoth K Ranganathan
Department of Biomedical Engineering/ND20, The Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Neuropsychologia 42:944-56. 2004..We conclude that the mental training employed by this study enhances the cortical output signal, which drives the muscles to a higher activation level and increases strength...
Heart rate as a predictor of energy expenditure in undisturbed fasting and incubating penguinsR Groscolas
Institut Pluridisciplinaire Hubert Curien, Departement d Ecologie, Physiologie et Ethologie, UMR 7178, 23 rue Becquerel, 67087 Strasbourg Cedex 02, France
J Exp Biol 213:153-60. 2010b>Heart rate (f(H)) measurement offers the possibility to monitor energy expenditure (EE) in wild animals if the EE/f(H) relationship for the species, physiological stages and activities of interest is known...
Autonomic specificity of basic emotions: evidence from pattern classification and cluster analysisChad L Stephens
Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 0436, USA
Biol Psychol 84:463-73. 2010..women) listened to emotion-inducing music and viewed affective films while a montage of ANS variables, including heart rate variability indices, peripheral vascular activity, systolic time intervals, and electrodermal activity, were ..
Multivariate short-term heart rate variability: a pre-diagnostic tool for screening heart diseaseAndreas Heitmann
Department of Medical Engineering and Biotechnology, University of Applied Sciences Jena, Jena, Germany
Med Biol Eng Comput 49:41-50. 2011..develop a novel pre-diagnostic tool for primary care screening of heart disease based on multivariate short-term heart rate variability (HRV) analyzed by linear (time and frequency domain) and nonlinear methods (compression entropy (CE),..
Insulin resistance and circadian rhythm of cardiac autonomic modulationSol M Rodriguez-Colon
Department of Public Health Sciences, Penn State University College of Medicine, 600 Centerview Dr, Suite 2200, A210, Hershey, PA, USA
Cardiovasc Diabetol 9:85. 2010Insulin resistance (IR) has been associated with cardiovascular diseases (CVD). Heart rate variability (HRV), an index of cardiac autonomic modulation (CAM), is also associated with CVD mortality and CVD morbidity...
Determination of exercise training heart rate in patients on beta-blockers after myocardial infarctionJean Yves Tabet
Les Grands Prés, Villeneuve Saint Denis, France
Eur J Cardiovasc Prev Rehabil 13:538-43. 2006In patients with coronary artery disease, the target intensity-level of exercise training is usually based on a training heart rate that aims to be close to the upper level of metabolic aerobic exercise.
Reduced heart rate variability predicts poor sleep quality in a case-control study of chronic fatigue syndromeA R Burton
School of Psychiatry, University of NSW, Sydney, Australia
Exp Brain Res 204:71-8. 2010..We examined whether nocturnal vagal modulation of heart rate is related to the poor sleep quality commonly reported in chronic fatigue syndrome (CFS)...
The cardiomyocyte circadian clock: emerging roles in health and diseaseDavid J Durgan
Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, 703 19th Street S, Birmingham, AL 35294, USA
Circ Res 106:647-58. 2010..The purpose of this review is therefore to highlight recent advances regarding the roles of the cardiomyocyte circadian clock in both myocardial physiology and pathophysiology (ie, health and disease)...
Executive and motivational control of performance task behavior, and autonomic heart-rate regulation in children: physiologic validation of two-factor solution inhibitory controlE Mezzacappa
Judge Baker Children s Center, Boston, MA 02115, USA
J Child Psychol Psychiatry 39:525-31. 1998..children underwent physiologic challenges of paced breathing and supine to standing postural change, while heart rate was continuously monitored...
Blood pressure and heart rate effects following a single dose of bitter orangeLinda T Bui
School of Pharmacy, University of California, San Francisco, CA, USA
Ann Pharmacother 40:53-7. 2006..Due to the similarity in chemical structure to ephedrine and the potential sympathomimetic effects of synephrine, it is hypothesized that bitter orange may increase blood pressure (BP) and heart rate (HR).
Cardiac autonomic functions are altered in patients with acute leukemia, assessed by heart rate variabilityOral Nevruz
Department of Hematology, Gulhane Military Medical School, Ankara, Turkey
Tohoku J Exp Med 211:121-6. 2007..designed to investigate the cardiac autonomic disturbances in acute leukemias by using time-domain indices of heart rate variability (HRV)...
Inhibition of THC-induced effects on the central nervous system and heart rate by a novel CB1 receptor antagonist AVE1625L Zuurman
Centre for Human Drug Research, Leiden, The Netherlands
J Psychopharmacol 24:363-71. 2010..was observed on Visual Analogue Scales 'alertness', 'feeling high', 'external perception', 'body sway' and 'heart rate'. Even the lowest dose of AVE1625 20 mg inhibited most of THC-induced effects...
Diurnal fluctuations of heart rate, body temperature and locomotor activity in the house musk shrew (Suncus murinus)Keiji Ishii
Department of Comparative Pathophysiology, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan
Exp Anim 51:57-62. 2002Diurnal fluctuations of heart rate (HR), body temperature (BT) and locomotor activity (LA) in the unanaesthetized and unrestrained house musk shrew (Suncus murinus) were studied using a telemetry system...
Combining GPS with heart rate monitoring to measure physical activity in children: A feasibility studyJ Scott Duncan
Centre for Physical Activity and Nutrition Research, Auckland University of Technology, New Zealand
J Sci Med Sport 12:583-5. 2009The recent development of global positioning system (GPS) receivers with integrated heart rate (HR) monitoring has provided a new method for estimating the energy expenditure associated with children's movement...
Cannabis coadministration potentiates the effects of "ecstasy" on heart rate and temperature in humansG J Dumont
Department of Psychiatry, Donders Institute for Brain, Cognition, and Behavior, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Clin Pharmacol Ther 86:160-6. 2009..Both single-drug conditions robustly increased heart rate, and coadministration showed additive effects...
Maximal exercise oxygen pulse as a predictor of mortality among male veterans referred for exercise testingRicardo B Oliveira
Gama Filho University, Rio de Janeiro, Brazil
Eur J Cardiovasc Prev Rehabil 16:358-64. 2009..Maximal oxygen pulse (O(2) pulse) mirrors the stroke volume response to exercise, and should therefore be a strong predictor of mortality. Limited and conflicting data are, however, available on this issue...
Accumulation of physical activity: blood pressure reduction between 10-min walking sessionsS Park
Division of Sports Science, Korea Institute of Sport Science, Seoul, Korea
J Hum Hypertens 22:475-82. 2008..7/82.5+/-6.4 mm Hg) participated in the study. BP using ambulatory monitoring and autonomic modulation through heart rate variability (HRV) using Holter monitoring were measured at baseline and during the rest periods following three ..
Evaluation of baroreceptor reflex function in the chronic mild stress rodent model of depressionAngela J Grippo
Department of Psychology, University of Iowa, Iowa City, IA 52242 1407, USA
Psychosom Med 70:435-43. 2008..The purpose of the present study was to more fully characterize baroreceptor reflex function in rats with experimentally induced depression...
Endurance training improves post-exercise cardiac autonomic modulation in obese women with and without type 2 diabetesArturo Figueroa
Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL 32306, USA
Eur J Appl Physiol 100:437-44. 2007..b>Heart rate (HR) variability (HRV) and baroreflex sensitivity (BRS) were measured at rest and 20 min after a 20 min bout of ..
Recovery pattern of baroreflex sensitivity after exerciseTeemu H Niemelä
Department of Exercise and Medical Physiology, Verve, Oulu, Finland
Med Sci Sports Exerc 40:864-70. 2008..To test the association between exercise mode and the recovery pattern of baroreflex sensitivity (BRS) after exercise...
Oxyntomodulin increases intrinsic heart rate in mice independent of the glucagon-like peptide-1 receptorGillian L Sowden
Department of Biology, Williams College, Williamstown, MA 01267, USA
Am J Physiol Regul Integr Comp Physiol 292:R962-70. 2007..Using telemetry to measure heart rate (HR), body temperature (Tb), and activity in conscious and freely moving mice, we tested 1) whether OXM affects ..
Autonomic compensation to simulated hemorrhage monitored with heart period variabilityWilliam H Cooke
Department of Health and Kinesiology, University of Texas at San Antonio, San Antonio, TX 78249, USA
Crit Care Med 36:1892-9. 2008..To test the hypothesis that components of heart period variability track autonomic function during simulated hemorrhage in humans...
Autonomic nervous function at rest in aerobically trained and untrained older menS H Boutcher
University of Exeter, Exeter, UK
Clin Physiol 17:339-46. 1997..aerobic training, vagal influence on the heart and ageing was examined by assessing aerobic fitness and resting heart rate variability in trained and untrained older men...
Variability of ventricular excitation interval does not reflect fluctuation in atrial excitation interval during exercise in humans: AV nodal function as stabilizerTomoko Nakamoto
Department of Physiology, Graduate School of Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, 734-8551 Japan
J Physiol Sci 56:67-77. 2006..However, it remained unknown at which level of heart rate (HR) this mechanism started to operate and whether fluctuation in the interval might influence AV conduction ..
Research Grants
- FETAL REFLEX RESPONSES TO CEREBRAL HYPOPERFUSIONCharles Wood; Fiscal Year: 1999..We have demonstrated that the reflex vasomotor and heart rate responses and the reflex hormonal responses are mediated by both baroreceptor- and chemoreceptor- reflexes...
- The baroreflex in pregnancy: effects of adrenal and placental steroidsMaureen Keller Wood; Fiscal Year: 2010..In nonpregnant ewes cortisol increases blood pressure and heart rate, and decreases baroreflex sensitvity;adrenalectomy and total withdrawal from adrenal steroids causes decreased ..
- Red Blood Cell Fatty Acid Biomarkers and Cardiovascular Disease RiskWilliam S Harris; Fiscal Year: 2010..A decrease in heart rate, an increase in heart rate variability, and improved endothelial function have all been associated with higher ..
- Sleep and Brain Structure in Heart FailureMARY ANN WOO; Fiscal Year: 2010..and changes in tissue properties and function, occurs in areas which regulate mood, memory, blood pressure, heart rate, and breathing. All of these symptoms have been linked to increased morbidity and mortality in HF...
- EMA Assessment of Biobehavioral Processes in Human PregnancyPathik D Wadhwa; Fiscal Year: 2010..Continuous ambulatory measures of maternal heart rate, respiration and physical activity, as well as seven saliva samples over the course of each day, will be ..
- Factors that Initiate Arrhythamias in Long QT SyndromeGuy Salama; Fiscal Year: 2006..Sympathetic and parasympathetic modulation of heart rate, conduction of the specialized conduction system and ventricular myocardium, AP upstroke velocity, APDs, DOR, ..
- The baroreflex in pregnancy: effects of adrenal and placental steroidsMaureen Keller Wood; Fiscal Year: 2009..In nonpregnant ewes cortisol increases blood pressure and heart rate, and decreases baroreflex sensitvity; adrenalectomy and total withdrawal from adrenal steroids causes decreased ..
- Autonomic consequences of brief seizuresMark Stewart; Fiscal Year: 2004..A broader spectrum of autonomic signs, including changes in heart rate and rhythm (most often bradycardia), blood pressure (most often pressure increases), pupillary size, vasomotor ..
- Factors that Initiate Arrhythmias in lung QT SyndromeGuy Salama; Fiscal Year: 2004..Sympathetic and parasympathetic modulation of heart rate, conduction of the specialized conduction system and ventricular myocardium, AP upstroke velocity, APDs, DOR, ..
- Lead, Cadmium,Arsenic, and cardiovascular risk in childrenEliseo Guallar; Fiscal Year: 2009..factor alpha [TNF-alpha]) in children; and 3) Exposures, cadmium, or arsenic are inversely associated with heart rate variability in children...
- Lead, Cadmium,Arsenic, and cardiovascular risk in childrenEliseo Guallar; Fiscal Year: 2011..factor alpha [TNF-alpha]) in children;and 3) Exposures, cadmium, or arsenic are inversely associated with heart rate variability in children...
- Lead, Cadmium,Arsenic, and cardiovascular risk in childrenEliseo Guallar; Fiscal Year: 2010..factor alpha [TNF-alpha]) in children;and 3) Exposures, cadmium, or arsenic are inversely associated with heart rate variability in children...
- CENTRAL BAROREFLEX MECHANISMS OF ANESTHETIC ACTIONMICHAEL ANDRESEN; Fiscal Year: 2000..general anesthetics cause cardiovascular dysfunction in part by compromising brainstem baroreflex control of heart rate via actions in the nucleus tractus solitarius (NTS) and nucleus ambiguus (NA)...
- Integrative Cardiovascular Control During Exercise in HypertensionDONAL S O apos LEARY; Fiscal Year: 2010..with established hypertension abnormally large increases in sympathetic nerve activity, arterial pressure and heart rate often occur in response to exercise which precludes advisement of any strenuous physical activity due to the ..
- Sleep and Brain Structure in Heart FailureMary Woo; Fiscal Year: 2009..and changes in tissue properties and function, occurs in areas which regulate mood, memory, blood pressure, heart rate, and breathing. All of these symptoms have been linked to increased morbidity and mortality in HF...
- The role of dynamic changes in repolarization and calcium transients in Long QT rBum Rak Choi; Fiscal Year: 2009..In addition, heart rate variation such as short-long-short cycle length (pause-dependent mode) or acceleration of heart rates often ..
- The role of dynamic changes in repolarization and calcium transients in Long QT rBum Rak Choi; Fiscal Year: 2010..In addition, heart rate variation such as short-long-short cycle length (pause-dependent mode) or acceleration of heart rates often ..
- Epigenetic Effects of Particles and Metals on Cardiac Health of an Aging CohortJoel Schwartz; Fiscal Year: 2009..particulate air pollution exposures are associated with specific cardiovascular outcomes, such as decreased heart rate variability, arterial stiffness, and ST-segment depression, resulting in increased death rates for CVD...
- Epigenetic Effects of Particles and Metals on Cardiac Health of an Aging CohortJoel Schwartz; Fiscal Year: 2007..particulate air pollution exposures are associated with specific cardiovascular outcomes, such as decreased heart rate variability, arterial stiffness, and ST-segment depression, resulting in increased death rates for CVD...
- Red Blood Cell Fatty Acid Biomarkers and Cardiovascular Disease RiskWilliam Harris; Fiscal Year: 2009..A decrease in heart rate, an increase in heart rate variability, and improved endothelial function have all been associated with higher ..
- Nicotine Modulation of Parasympathetic Cardiac NeuronsDavid Mendelowitz; Fiscal Year: 2009..Electrical or mechanical stimulation of the trigeminal nerve evokes a dramatic decrease in heart rate in animals including man, and has often been termed the `trigeminocardiac reflex' in the clinical ..
- Nicotine Modulation of Parasympathetic Cardiac NeuronsDavid Mendelowitz; Fiscal Year: 2010..Electrical or mechanical stimulation of the trigeminal nerve evokes a dramatic decrease in heart rate in animals including man, and has often been termed the `trigeminocardiac reflex'in the clinical literature,..
- PREDICTING FETAL ACIDEMIA WITH INTRAPARTUM ELECTRONIC FETAL HEART RATE MONITORINGGeorge A Macones; Fiscal Year: 2010DESCRIPTION (provided by investigator): Intrapartum electronic fetal heart rate monitoring (EFM) has become the most frequently used instrument in obstetrics in the United States, despite its classification as a "D" by the U.S...
- HEART RATE RECOVERY AND MORTALITYMichael Lauer; Fiscal Year: 2002Although there has been considerable attention paid to the prognostic significance of the heart rate rise during exercise, only recently has it been noted that the heart rate fall after exercise, or "heart-rate recovery," may be an even ..
- Spontaneous Arousals in "CHIME" Infants at Risk for SIDSROBERT DARNALL; Fiscal Year: 2006..Subcortical arousals associated with changes in breathing, blood pressure, heart rate, and heart rate variability, may be particularly important in infants...
- Y Receptor In and Cardiovascular Function From the PHNJohn Martin; Fiscal Year: 2004..by the pancreatic polypeptide neuropeptide Y (NPY) that mediates increases in mean arterial pressure (MAP) and heart rate (HR), and to explore the mechanism by which the related pancreatic polypeptide PYY, which appears to stimulate a ..
- IN VITRO MODEL OF PRECONDITIONING WITH ISOLATED MYOCYTESCHARLES GANOTE; Fiscal Year: 2001..of ischemic preconditioning using isolated cardiac myocytes from rabbits, as an example of an animal with a fast heart rate, and from pigs, as an example of an animal with a slow heart rate...
- Role of Sterols and Insulin in Cardiac Autonomic ResponseJONAS BERNARD GALPER; Fiscal Year: 2010..IKACh, the hyperpolarizing K+ current that causes a hyperpolarization of the cardiac membrane and a decrease in heart rate. Sterol regulatory element binding proteins (SREBPs) are the transcription factors that regulate genes involved ..
- Biobehavioral Cardiovascular Health Promotion Intervention in a State Prison SystDebra Moser; Fiscal Year: 2009..e., Cooper Clinic Mortality Risk Index [a composite index that includes heart rate, blood pressure, diabetes, smoking status, body mass index, age, and cardio-respiratory fitness], lipid profile, ..
- Spiral Electrode Sensor for Intrapartum Fetal OximetryJONAS POLOGE; Fiscal Year: 2003Fetal heart rate monitoring is intended to detect signs of fetal distress due to oxygen starvation of the fetus...
- Physiologic Responses to Simulated Care Activities in Older Surgical PatientsColleen Casey; Fiscal Year: 2007..This study aims to evaluate the utility of using the ActiHeart(tm), a type of actigraph that measures motion and heart rate simultaneously, to measure simulated clinical care activities with older adults prior to their hospitalization ..
