blood pressure

Summary

Summary: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.

Top Publications

  1. ncbi Role of blood pressure reduction in prevention of cardiac and vascular hypertrophy
    Hiroshi Yokoyama
    Hypertension and Vascular Disease Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA
    Am J Hypertens 18:922-9. 2005
  2. ncbi Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
    Aram V Chobanian
    Boston University School of Medicine, Boston, Mass, USA
    Hypertension 42:1206-52. 2003
  3. ncbi The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report
    Aram V Chobanian
    Department of Medicine, Boston University School of Medicine, Boston, Mass, USA
    JAMA 289:2560-72. 2003
  4. ncbi Prediction of coronary heart disease using risk factor categories
    P W Wilson
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Mass 01701, USA
    Circulation 97:1837-47. 1998
  5. ncbi Expert consensus document on arterial stiffness: methodological issues and clinical applications
    Stephane Laurent
    Department of Pharmacology and Hôpital Européen Georges Pompidou, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, INSERM U652, 20 rue Leblanc, 75015 Paris, France
    Eur Heart J 27:2588-605. 2006
  6. ncbi 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
    Giuseppe Mancia
    Clinica Medica, Ospedale San Gerardo, , Via Pergolesi, 33 - 20052 MONZA (Milano, Italy
    J Hypertens 25:1105-87. 2007
  7. ncbi Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group
    F M Sacks
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, USA
    N Engl J Med 344:3-10. 2001
  8. ncbi A genome-wide association study of hypertension and blood pressure in African Americans
    Adebowale Adeyemo
    Center for Research on Genomics and Global Health, National Human Genome Research Institute, NIH, Bethesda, MD, USA
    PLoS Genet 5:e1000564. 2009
  9. ncbi 2007 ESH-ESC Practice Guidelines for the Management of Arterial Hypertension: ESH-ESC Task Force on the Management of Arterial Hypertension
    Giuseppe Mancia
    University of Milano-Bicocca, Ospedale San Gerardo, Milan, Italy
    J Hypertens 25:1751-62. 2007
  10. ncbi Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies
    M R Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ
    BMJ 338:b1665. 2009

Research Grants

  1. FETAL REFLEX RESPONSES TO CEREBRAL HYPOPERFUSION
    Charles Wood; Fiscal Year: 1999
  2. Mechanims of CNS Autonomic Regulation by EA
    John C Longhurst; Fiscal Year: 2010
  3. The baroreflex in pregnancy: effects of adrenal and placental steroids
    Maureen Keller Wood; Fiscal Year: 2009
  4. The baroreflex in pregnancy: effects of adrenal and placental steroids
    Maureen Keller Wood; Fiscal Year: 2010
  5. Older Mothers and Adult Daughters: High Blood Pressure Self Management Behaviors
    Celeste Shawler; Fiscal Year: 2010
  6. Older Mothers and Adult Daughters: High Blood Pressure Self Management Behaviors
    Celeste Shawler; Fiscal Year: 2009
  7. Chicago Endothelial Function Study
    LOUISE HAWKLEY; Fiscal Year: 2009
  8. Chicago Endothelial Function Study
    Louise C Hawkley; Fiscal Year: 2010
  9. IINFLUENCE OF INSULIN ON BLOOD PRESSURE CHANGE DURING AD
    Alan Sinaiko; Fiscal Year: 1999
  10. CONTROL OF VASCULAR TONE BY CONTINGENT CNS STIMULATION
    Barry Dworkin; Fiscal Year: 2006

Detail Information

Publications255 found, 100 shown here

  1. ncbi Role of blood pressure reduction in prevention of cardiac and vascular hypertrophy
    Hiroshi Yokoyama
    Hypertension and Vascular Disease Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA
    Am J Hypertens 18:922-9. 2005
    ..of cardiac and vascular remodeling associated with inhibition of angiotensin II is independent of the blood pressure (BP)-lowering action of angiotensin II type 1 (AT1) receptor blockade...
  2. ncbi Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
    Aram V Chobanian
    Boston University School of Medicine, Boston, Mass, USA
    Hypertension 42:1206-52. 2003
    The National High Blood Pressure Education Program presents the complete Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure...
  3. ncbi The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report
    Aram V Chobanian
    Department of Medicine, Boston University School of Medicine, Boston, Mass, USA
    JAMA 289:2560-72. 2003
    ..Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure" provides a new guideline for hypertension prevention and management...
  4. ncbi Prediction of coronary heart disease using risk factor categories
    P W Wilson
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Mass 01701, USA
    Circulation 97:1837-47. 1998
    The objective of this study was to examine the association of Joint National Committee (JNC-V) blood pressure and National Cholesterol Education Program (NCEP) cholesterol categories with coronary heart disease (CHD) risk, to incorporate ..
  5. ncbi Expert consensus document on arterial stiffness: methodological issues and clinical applications
    Stephane Laurent
    Department of Pharmacology and Hôpital Européen Georges Pompidou, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, INSERM U652, 20 rue Leblanc, 75015 Paris, France
    Eur Heart J 27:2588-605. 2006
    ....
  6. ncbi 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
    Giuseppe Mancia
    Clinica Medica, Ospedale San Gerardo, , Via Pergolesi, 33 - 20052 MONZA (Milano, Italy
    J Hypertens 25:1105-87. 2007
  7. ncbi Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group
    F M Sacks
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, USA
    N Engl J Med 344:3-10. 2001
    The effect of dietary composition on blood pressure is a subject of public health importance...
  8. ncbi A genome-wide association study of hypertension and blood pressure in African Americans
    Adebowale Adeyemo
    Center for Research on Genomics and Global Health, National Human Genome Research Institute, NIH, Bethesda, MD, USA
    PLoS Genet 5:e1000564. 2009
    ..We sought genetic variants underlying blood pressure (BP) by conducting a genome-wide association study (GWAS) among African Americans, a population group in the ..
  9. ncbi 2007 ESH-ESC Practice Guidelines for the Management of Arterial Hypertension: ESH-ESC Task Force on the Management of Arterial Hypertension
    Giuseppe Mancia
    University of Milano-Bicocca, Ospedale San Gerardo, Milan, Italy
    J Hypertens 25:1751-62. 2007
  10. ncbi Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies
    M R Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ
    BMJ 338:b1665. 2009
    To determine the quantitative efficacy of different classes of blood pressure lowering drugs in preventing coronary heart disease (CHD) and stroke, and who should receive treatment.
  11. ncbi Lead exposure and cardiovascular disease--a systematic review
    Ana Navas Acien
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Environ Health Perspect 115:472-82. 2007
    ..This systematic review evaluates the evidence on the association between lead exposure and cardiovascular end points in human populations...
  12. ncbi Prevalence and factors associated with circadian blood pressure patterns in hypertensive patients
    Alejandro de la Sierra
    Hypertension Unit, Department of Internal Medicine, Hospital Clinic, University of Barcelona, Villarroel 170, E 08036 Barcelona, Spain
    Hypertension 53:466-72. 2009
    Ambulatory blood pressure (BP) monitoring has become useful in the diagnosis and management of hypertensive individuals...
  13. ncbi Effects of comprehensive lifestyle modification on diet, weight, physical fitness, and blood pressure control: 18-month results of a randomized trial
    Patricia J Elmer
    Kaiser Permanente Northwest, Portland, Oregon 97227, USA
    Ann Intern Med 144:485-95. 2006
    ..PREMIER trial showed that comprehensive behavioral intervention programs improve lifestyle behaviors and lower blood pressure. OBJECTIVE: To compare the 18-month effects of 2 multicomponent behavioral interventions versus advice only on ..
  14. ncbi Effect of aerobic exercise on blood pressure: a meta-analysis of randomized, controlled trials
    Seamus P Whelton
    Tulane University, New Orleans, Louisiana 70112, USA
    Ann Intern Med 136:493-503. 2002
    PURPOSE: Physical activity has been associated with reduced blood pressure in observational epidemiologic studies and individual clinical trials...
  15. ncbi Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States
    Katharina Wolf-Maier
    Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, Ill 60153, USA
    JAMA 289:2363-9. 2003
    ..OBJECTIVE: To determine whether higher blood pressure (BP) levels and hypertension are more prevalent in Europe than in the United States and Canada...
  16. ncbi Role of the WNK-activated SPAK kinase in regulating blood pressure
    Fatema H Rafiqi
    University of Dundee, Scotland, UK
    EMBO Mol Med 2:63-75. 2010
    ..To define the importance of this pathway in regulating blood pressure, we generated knock-in mice in which SPAK cannot be activated by WNKs...
  17. ncbi Ambulatory arterial stiffness index as a predictor of cardiovascular mortality in the Dublin Outcome Study
    Eamon Dolan
    The ADAPT Centre, Beaumont Hospital, Department of Clinical Pharmacology, Royal College of Surgeons in Ireland, Dublin, Ireland
    Hypertension 47:365-70. 2006
    We hypothesized that the dynamic relation between diastolic and systolic blood pressure over 24 hours provides a measure of arterial stiffness and might, therefore, predict cardiovascular mortality over and above pulse pressure...
  18. ncbi Genome-wide association study of blood pressure and hypertension
    Daniel Levy
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts, USA
    Nat Genet 41:677-87. 2009
    b>Blood pressure is a major cardiovascular disease risk factor. To date, few variants associated with interindividual blood pressure variation have been identified and replicated...
  19. ncbi Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice
    F E Rey
    Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, MI 48202-2689, USA
    Circ Res 89:408-14. 2001
    ..kg(-1). d(-1)), or Ang II+scramb-tat intraperitoneally in C57Bl/6 mice and measured systolic blood pressure (SBP) on days 0, 3, 5, and 7 of infusion...
  20. ncbi Insights into the mechanisms and mediators of the effects of air pollution exposure on blood pressure and vascular function in healthy humans
    Robert D Brook
    University of Michigan, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48106, USA
    Hypertension 54:659-67. 2009
    Fine particulate matter air pollution plus ozone impairs vascular function and raises diastolic blood pressure. We aimed to determine the mechanism and air pollutant responsible...
  21. ncbi Long-term effects of parathyroidectomy on hypertension prevalence and circadian blood pressure profile in primary hyperparathyroidism
    Carlos A Feldstein
    Hypertension Program, Hospital de Clinicas Jose de San Martin, School of Medicine, Universidad de Buenos Aires, Buenos Aires 1120, Argentina
    Clin Exp Hypertens 32:154-8. 2010
    ..consecutive parathyroidectomized patients, with normalized biochemical measurements, circadian rhythm of blood pressure was evaluated with ambulatory blood pressure monitoring (ABPM). Prevalence of hypertension in PHPT was 54...
  22. ncbi Stress reduction programs in patients with elevated blood pressure: a systematic review and meta-analysis
    Maxwell V Rainforth
    Institute for Natural Medicine and Prevention, Maharishi University of Management, 2100 Mansion Drive, Suite 211, Maharishi Vedic City, IA 52556, USA
    Curr Hypertens Rep 9:520-8. 2007
    ..Previous meta-analyses of stress reduction and high blood pressure (BP) were outdated and/or methodologically limited...
  23. ncbi Randomized placebo-controlled trial of continuous positive airway pressure on blood pressure in the sleep apnea-hypopnea syndrome
    J F Faccenda
    Respiratory Medicine Unit and Cardiovascular Unit, University of Edinburgh, Royal Infirmary, Edinburgh, Scotland, United Kingdom
    Am J Respir Crit Care Med 163:344-8. 2001
    Arterial blood pressure rises at apnea termination, and there is increasing evidence that the sleep apnea-hypopnea syndrome (SAHS) is associated with daytime hypertension but no randomized controlled trial evidence of whether SAHS ..
  24. ncbi Blood pressure in Canadian adults
    Kathryn Wilkins
    Health Analysis Division, Statistics Canada, Ottawa, Ontario, K1A 0T6
    Health Rep 21:37-46. 2010
    Hypertension is estimated to cause more than one-eighth of all deaths worldwide. In Canada, the last national surveys to include direct measures of blood pressure (BP) took place over the years 1985-1992; hypertension was estimated at 21%.
  25. ncbi Feasibility of treating prehypertension with an angiotensin-receptor blocker
    Stevo Julius
    University of Michigan, Department of Internal Medicine, Division of Cardiovascular Medicine, Ann Arbor, MI 48106, USA
    N Engl J Med 354:1685-97. 2006
    ..Prehypertension is considered a precursor of stage 1 hypertension and a predictor of excessive cardiovascular risk. We investigated whether pharmacologic treatment of prehypertension prevents or postpones stage 1 hypertension...
  26. ncbi Environmental mercury exposure and blood pressure among Nunavik Inuit adults
    Beatriz Valera
    Axe Santé des Populations et Environnement, Centre de Recherche du Centre Hospitalier Universitaire de Québec, Quebec, Canada
    Hypertension 54:981-6. 2009
    ..suggests a negative impact of methylmercury on the cardiovascular system, but findings regarding the effect on blood pressure (BP) are not consistent. We aimed to study the impact of mercury levels on BP among Nunavik Inuit adults...
  27. ncbi Trends in blood pressure among children and adolescents
    Paul Muntner
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA
    JAMA 291:2107-13. 2004
    The prevalence of overweight among children and adolescents increased between 1988 and 2000. The change in blood pressure among children and adolescents over that time and the role of overweight is unknown.
  28. ncbi Using pedometers to increase physical activity and improve health: a systematic review
    Dena M Bravata
    Center for Primary Care and Outcomes Research, Stanford University, Stanford, California, USA
    JAMA 298:2296-304. 2007
    ..Without detailed evidence of their effectiveness, pedometers have recently become popular as a tool for motivating physical activity...
  29. ncbi Central pressure more strongly relates to vascular disease and outcome than does brachial pressure: the Strong Heart Study
    Mary J Roman
    Division of Cardiology, Weill Medical College of Cornell University, New York, NY 10021, USA
    Hypertension 50:197-203. 2007
    Brachial blood pressure is predictive of cardiovascular outcome; however central pressure may better represent the load imposed on the coronary and cerebral arteries and thereby bear a stronger relationship to vascular damage and ..
  30. ncbi Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths
    Sarah Lewington
    CTSU, University of Oxford, Oxford OX3 7LF, UK
    Lancet 370:1829-39. 2007
    Age, sex, and blood pressure could modify the associations of total cholesterol (and its main two fractions, HDL and LDL cholesterol) with vascular mortality...
  31. ncbi The effect of walking on fitness, fatness and resting blood pressure: a meta-analysis of randomised, controlled trials
    Marie H Murphy
    Sport and Exercise Sciences Research Institute, School of Health Sciences, University of Ulster at Jordanstown, Newtownabbey Co Antrim, Northern Ireland, BT37 0QB, UK
    Prev Med 44:377-85. 2007
    ..The purpose of this review was to perform a meta-analysis on walking intervention studies in order to quantify the magnitude and direction of walking-induced changes that may alter selected cardiovascular risk factors...
  32. ncbi Telmisartan, ramipril, or both in patients at high risk for vascular events
    Salim Yusuf
    Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada
    N Engl J Med 358:1547-59. 2008
    ..We compared the ACE inhibitor ramipril, the ARB telmisartan, and the combination of the two drugs in patients with vascular disease or high-risk diabetes...
  33. ncbi Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial
    Jackson T Wright
    Case Western Reserve University, Department of Medicine, University Hospitals of Cleveland and the Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH 44106 5014, USA
    JAMA 288:2421-31. 2002
    ..Hypertension is a leading cause of end-stage renal disease (ESRD) in the United States, with no known treatment to prevent progressive declines leading to ESRD...
  34. ncbi Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: principal results of a prospective randomized controlled study (MOSES)
    Joachim Schrader
    Department of Internal Medicine, St. Josefs Hospital, Cloppenburg, Germany
    Stroke 36:1218-26. 2005
    BACKGROUND AND PURPOSE: In hypertensive stroke patients, for the same level of blood pressure control, eprosartan will be more effective than nitrendipine in reducing cerebrovascular and cardiovascular morbidity and mortality...
  35. ncbi Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis
    F G R Fowkes
    JAMA 300:197-208. 2008
    ..CONCLUSION: Measurement of the ABI may improve the accuracy of cardiovascular risk prediction beyond the FRS...
  36. ncbi Prospective evaluation of a method for estimating ascending aortic pressure from the radial artery pressure waveform
    A L Pauca
    Anesthesiology Departmen, Wake Forest University School of Medicine, Winston-Salem, NC, USA
    Hypertension 38:932-7. 2001
    ..5+/-7.3 and 15.1+/-7.3 mm Hg for nitroglycerin). Use of a generalized transfer function to synthesize radial artery pressure waveforms can provide substantially equivalent values of aortic systolic, pulse, mean, and diastolic pressures...
  37. ncbi Effects of diet and sodium intake on blood pressure: subgroup analysis of the DASH-sodium trial
    W M Vollmer
    Center for Health Research, 3800 North Interstate Avenue, Portland, OR 97227, USA
    Ann Intern Med 135:1019-28. 2001
    ..Hypertension (DASH)-Sodium Trial demonstrated that reduction of sodium intake in two different diets decreased blood pressure in participants with and without hypertension...
  38. ncbi The renin inhibitor aliskiren upregulates pro-angiogenic cells and reduces atherogenesis in mice
    Janine Pöss
    Klinik fur Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Kirrbergerstr, 66421, Homburg, Saar, Germany
    Basic Res Cardiol 105:725-35. 2010
    ..c. for 3-6 weeks, reduced systolic and diastolic blood pressure by -11.5 and -13.7% compared to vehicle...
  39. ncbi Clinical risk factors, DNA variants, and the development of type 2 diabetes
    Valeriya Lyssenko
    Department of Clinical Sciences, Lund University, Malmo, Sweden
    N Engl J Med 359:2220-32. 2008
    ..Type 2 diabetes mellitus is thought to develop from an interaction between environmental and genetic factors. We examined whether clinical or genetic factors or both could predict progression to diabetes in two prospective cohorts...
  40. ncbi National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5·4 million participants
    Goodarz Danaei
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Lancet 377:568-77. 2011
    Data for trends in blood pressure are needed to understand the effects of its dietary, lifestyle, and pharmacological determinants; set intervention priorities; and evaluate national programmes...
  41. ncbi Associations of gestational weight gain with offspring body mass index and blood pressure at 21 years of age: evidence from a birth cohort study
    Abdullah A Mamun
    School of Population Health, University of Queensland, Herston Rd, Herston, QLD 4006, Australia
    Circulation 119:1720-7. 2009
    ..with offspring body mass index (BMI) and obesity risk in childhood, but whether this increased risk extends into adulthood or results in increases in other cardiovascular risk factors such as elevated blood pressure (BP) is unclear.
  42. ncbi Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism
    Agnes Machnik
    Department of Nephrology and Hypertension, and Nikolaus Fiebiger Centre for Molecular Medicine, University Clinic and Friedrich Alexander University of Erlangen Nuremberg, Germany
    Nat Med 15:545-52. 2009
    ..interstitial hypertonic volume retention, decreases endothelial nitric oxide synthase expression and elevates blood pressure in response to HSD...
  43. ncbi Losartan decreases cardiac muscle fibrosis and improves cardiac function in dystrophin-deficient mdx mice
    Christopher F Spurney
    Division of Cardiology, Children s National Medical Center, Washington, DC, USA
    J Cardiovasc Pharmacol Ther 16:87-95. 2011
    ..9% ± 3.5%) mice compared to losartan-treated (32.2% ± 4.2%; P < .01) mice. Systolic blood pressure was significantly reduced in losartan-treated mice (56 ± 6 vs 69 ± 7 mm Hg; P < .0005)...
  44. ncbi Clinical course of advanced non-small-cell lung cancer patients experiencing hypertension during treatment with bevacizumab in combination with carboplatin and paclitaxel on ECOG 4599
    Suzanne E Dahlberg
    Department of Biostatistics and Computational Biology, CLSB 11007, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    J Clin Oncol 28:949-54. 2010
    ..with nonhypertensive patients with respect to overall survival (OS) and progression-free survival (PFS) using blood pressure data and adverse event data separately...
  45. ncbi Effects of environmental noise exposure on ambulatory blood pressure in young adults
    Ta Yuan Chang
    Department of Occupational Safety and Health, College of Public Health, China Medical University, 91 Hsueh Shih Road, Taichung 40402, Taiwan, ROC
    Environ Res 109:900-5. 2009
    ..This panel study investigated effects of environmental noise exposure on 24-h ambulatory blood pressure in 60 adults aged 18-32 years...
  46. ncbi Initial assessment, surveillance, and management of blood pressure in patients receiving vascular endothelial growth factor signaling pathway inhibitors
    Michael L Maitland
    Department of Medicine, University of Chicago Medical Center, 5841Chicago, IL 60637, USA
    J Natl Cancer Inst 102:596-604. 2010
    ..The panel reviewed: the published literature on blood pressure (BP), hypertension, and specific VSP inhibitors; abstracts from major meetings; shared experience with the ..
  47. ncbi Blood pressure and hypertension in relation to levels of serum polychlorinated biphenyls in residents of Anniston, Alabama
    Alexey Goncharov
    Department of Environmental Health Sciences, School of Public Health, University at Albany, Rensselaer, New York 12144, USA
    J Hypertens 28:2053-60. 2010
    To determine risk factors for elevated blood pressure and hypertension in residents of Anniston, Alabama who live near a plant that manufactured polychlorinated biphenyls (PCBs).
  48. ncbi Prehypertension and mortality in a nationally representative cohort
    Arch G Mainous
    Department of Family Medicine, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Cardiol 94:1496-500. 2004
    The Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure 7 recommendations include early identification of prehypertension (120 to 139 mm Hg systolic or 80 to 89 mm Hg diastolic)...
  49. ncbi The sympathetic control of blood pressure
    Patrice G Guyenet
    Department of Pharmacology, Health Sciences Center, University of Virginia, 1300 Jefferson Park Avenue, Charlottesville, Virginia 22908 0735, USA
    Nat Rev Neurosci 7:335-46. 2006
    Hypertension - the chronic elevation of blood pressure - is a major human health problem...
  50. ncbi Metabolic syndrome and salt sensitivity of blood pressure in non-diabetic people in China: a dietary intervention study
    Jing Chen
    Department of Medicine and Tulane Hypertension and Renal Center of Excellence, School of Medicine, Tulane University, New Orleans, LA, USA
    Lancet 373:829-35. 2009
    ..We aimed to examine the association between metabolic syndrome and salt sensitivity of blood pressure.
  51. ncbi C-reactive protein and the risk of developing hypertension
    Howard D Sesso
    Department of Medicine, Center for Cardiovascular Disease Prevention and the Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02215 1204, USA
    JAMA 290:2945-51. 2003
    ..Although it has been hypothesized that hypertension is in part an inflammatory disorder, clinical data linking inflammation with incident hypertension are scarce...
  52. ncbi Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Circulation 113:1213-25. 2006
    BACKGROUND: Different blood pressure (BP)-lowering drugs could have different effects on central aortic pressures and thus cardiovascular outcome despite similar effects on brachial BP...
  53. ncbi Obesity and the metabolic syndrome in Korean adolescents
    So Yeon Ryu
    Department of Preventive Medicine, Chosun University College of Medicine, 375 Seosuk dong, Dong Gu, Gwangju, Korea
    J Korean Med Sci 22:513-7. 2007
    ..mg/dL; fasting glucose > or =110 mg/dL; waist circumference >75th percentile for age and gender; and systolic blood pressure >90th percentile for age, gender, and height...
  54. ncbi Midlife blood pressure and dementia: the Honolulu-Asia aging study
    L J Launer
    Epidemiology, Demography and Biometry Program, National Institute on Aging, National Institutes of Health, Gateway Building 3C 309, 7201 Wisconsin Avenue, Bethesda, MD 20892, USA
    Neurobiol Aging 21:49-55. 2000
    We studied the association of mid-life blood pressure to late age dementia, specifically Alzheimer's disease and vascular dementia...
  55. ncbi Subendocardial viability ratio estimated by arterial tonometry: a critical evaluation in elderly hypertensive patients with increased aortic stiffness
    Denis Chemla
    Paris Sud University, Research Team EA4046, Le Kremlin Bicetre, France
    Clin Exp Pharmacol Physiol 35:909-15. 2008
    ..4. The tonometric SEVR was not impaired in elderly hypertensive patients with increased aortic stiffness. In resting elderly and middle-aged individuals, the tonometric SEVR was mainly related to DT/ST ratio, not to aortic pressure...
  56. ncbi Central but not brachial blood pressure predicts cardiovascular events in an unselected geriatric population: the ICARe Dicomano Study
    Riccardo Pini
    Department of Critical Care Medicine and Surgery Unit of Geriatric Cardiology, University of Firenze and Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    J Am Coll Cardiol 51:2432-9. 2008
    The present study investigated whether central blood pressure (BP) predicts cardiovascular (CV) events better than brachial BP in a cohort of normotensive and untreated hypertensive elderly individuals.
  57. ncbi Association of polychlorinated biphenyls with hypertension in the 1999-2002 National Health and Nutrition Examination Survey
    Charles J Everett
    Department of Family Medicine, Medical University of South Carolina, 295 Calhoun Street, MSC 192, Charleston, SC 9425 1920, USA
    Environ Res 108:94-7. 2008
    ..What clinicians can do, given the results of this study, is limited unless the appropriate laboratory methods can be made more widely available for testing patients...
  58. ncbi Eplerenone prevents salt-induced vascular remodeling and cardiac fibrosis in stroke-prone spontaneously hypertensive rats
    Dierk H Endemann
    CIHR Multidisciplinary Research Group on Hypertension, Clinical Research Institute of Montreal, Canada
    Hypertension 43:1252-7. 2004
    ..A group of high-salt SHRSP was also treated with hydralazine (25 mg/kg per day). Blood pressure increased more in high-salt rats than in other groups (P<0.001)...
  59. ncbi Blood pressure differences between northern and southern Chinese: role of dietary factors: the International Study on Macronutrients and Blood Pressure
    Liancheng Zhao
    Department of Epidemiology, Fu Wai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences, Beijing, People's Republic of China
    Hypertension 43:1332-7. 2004
    b>Blood pressure and prevalence of high blood pressure are greater for northern than southern Chinese. Reasons for these differences are unclear...
  60. ncbi Heart rate dependency of pulse pressure amplification and arterial stiffness
    Ian B Wilkinson
    Clinical Pharmacology Unit, University of Edinburgh, Western General Hospital, United Kingdom
    Am J Hypertens 15:24-30. 2002
    ..The aim of the present study was to assess the effect of acute changes in heart rate on arterial stiffness and on peripheral and central pulse pressure in healthy subjects...
  61. ncbi Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function
    Brit Rentzsch
    Max Delbruck Center for Molecular Medicine, Berlin Buch, Germany
    Hypertension 52:967-73. 2008
    ..Mean arterial blood pressure was reduced in SHRSP-ACE2 compared to SHRSP rats, and the vasoconstrictive response to intraarterial ..
  62. ncbi Salt sensitivity, pulse pressure, and death in normal and hypertensive humans
    M H Weinberger
    Indiana University School of Medicine, The Regenstrief Institute for Health Care, Roudebush Veteran s Administration Medical Center, Indianapolis, Indiana, USA
    Hypertension 37:429-32. 2001
    Although factors such as age, blood pressure, and its responsiveness to changes in sodium balance and extracellular fluid volume status (salt sensitivity) are associated with an increased risk of end-organ disease and cardiovascular ..
  63. ncbi Increase in kinins on post-exercise hypotension in normotensive and hypertensive volunteers
    Milton R Moraes
    Department of Biophysics, Federal University of Sao Paulo, Sao Paulo, Brazil
    Biol Chem 388:533-40. 2007
    Post-exercise hypotension is an important event for blood pressure regulation, especially in hypertensive individuals. Although post-exercise hypotension is a well-known phenomenon, the mechanism responsible is still unclear...
  64. ncbi Contribution of the subfornical organ to angiotensin II-induced hypertension
    Michael D Hendel
    Department of Veterinary and Biomedical Sciences, University of Minnesota, St Paul, Minnesota 55108, USA
    Am J Physiol Heart Circ Physiol 288:H680-5. 2005
    ..venous catheters and radiotelemetric transducers for intravenous administration of ANG II and measurement of blood pressure and heart rate, respectively. Rats were then allowed 1 wk for recovery...
  65. ncbi Amlodipine attenuates oxidative stress-induced hypertension
    Agaba A Ganafa
    Department of Pharmacology/Toxicology, Morehouse School of Medicine, Atlanta, Georgia 30310-1495, USA
    Am J Hypertens 17:743-8. 2004
    ..The control animals received drug-free water. Blood pressure (BP) was measured by tail-cuff plethysmography...
  66. ncbi Predictive adaptive responses to maternal high-fat diet prevent endothelial dysfunction but not hypertension in adult rat offspring
    Imran Khan
    Maternal and Fetal Research Unit, Division of Reproductive Health, Endocrinology, and Development, Kings' College, London, UK
    Circulation 110:1097-102. 2004
    ..Vascular endothelial function and blood pressure were determined in 180-day-old offspring of fat-fed dams raised on standard chow (FC) or on the fat-rich diet (..
  67. ncbi Leptin and heart sympathetic activity in normotensive obese and non-obese subjects
    Norma Amador
    Epidemiology Research Unit, Mexican Institute of Social Security,
    Ital Heart J 5:29-35. 2004
    ..05). The LF/HF index showed a univariate correlation with body mass index, leptin, systolic blood pressure, insulin, age and triglyceride levels...
  68. ncbi Attenuation of insulin-mediated pressor effect and nitric oxide release in rats with fructose-induced insulin resistance
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, National Defense University, Taipei, Taiwan, Republic of China
    Am J Hypertens 17:707-711. 2004
    ..This study aimed to identify the specific effect of hyperinsulinemia on blood pressure and nitric oxide (NO) release in fructose-induced hyperinsulinemic, insulin-resistant rats...
  69. ncbi Disruption of ultradian and circadian rhythms of blood pressure in nondipper hypertensive patients
    Santiago Perez-Lloret
    Department of Physiology, Faculty of Medicine, University of Buenos Aires, Argentina
    Hypertension 44:311-5. 2004
    Ultradian rhythms in blood pressure (BP) are known to exist, but their modification in hypertension is largely unknown...
  70. ncbi Moxonidine in the treatment of overweight and obese patients with the metabolic syndrome: a postmarketing surveillance study
    A M Sharma
    McMaster University, Hamilton, ON, Canada
    J Hum Hypertens 18:669-75. 2004
    Moxonidine is a centrally active imidazoline receptor agonist that effectively lowers blood pressure and has been shown to have beneficial effects on lipid and carbohydrate metabolism...
  71. ncbi Pulse pressure is more susceptible to the white coat effect than is systolic blood pressure: observations from real-life ambulatory blood pressure monitoring
    Iddo Z Ben-Dov
    Department of Internal Medicine, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel
    Am J Hypertens 17:535-9. 2004
    ..We have previously demonstrated ambulatory pulse pressure to be relatively independent from the blood pressure (BP) lowering during sleep, and thus of a neurogenic effect...
  72. ncbi Amlodipine decreases fibrosis and cardiac hypertrophy in spontaneously hypertensive rats: persistent effects after withdrawal
    Maria A Sevilla
    Laboratorio de Farmacognosia y Farmacología, Facultad de Farmacia, Departamento de Fisiologia y Farmacologia, Universidad de Salamanca, Campus Miguel de Unamuno, Salamanca 37007, Spain
    Life Sci 75:881-91. 2004
    Our objective was to examine the effect of chronic treatment with amlodipine on blood pressure, left ventricular hypertrophy, and fibrosis in spontaneously hypertensive rats and the persistence of such an effect after drug withdrawal...
  73. ncbi Functional interaction of AT1 and AT2 receptors in fructose-induced insulin resistance and hypertension in rats
    Po Shiuan Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, National Defense University, Taipei, Taiwan 114
    Metabolism 54:157-64. 2005
    ..role and functional interaction of angiotensin II AT1 and AT2 receptors (AT1R and AT2R) in the regulation of blood pressure and glucose homeostasis in fructose-induced insulin-resistant, hypertensive rats...
  74. ncbi Triple vasopeptidase inhibition of angiotensin-converting enzyme/neutral endopeptidase/endothelin-converting enzyme activities on the hemodynamic profile of chronically instrumented unrestrained conscious spontaneously hypertensive rats
    Philippe Daull
    Laval Hospital Research Center, Quebec Heart and Lung Institute, Laval University, Quebec, QC, Canada
    J Cardiovasc Pharmacol 44:S398-401. 2004
    ..After 15 days, drugs administration was stopped for 3 days. ACEi (1 mg/kg per day) reduced the mean arterial blood pressure by 8.4%. The addition of a NEPi and an ECEi at the same dose did not shown any added benefit...
  75. ncbi Amlodipine/benazepril combination therapy for hypertensive patients nonresponsive to benazepril monotherapy
    Steven G Chrysant
    Oklahoma Cardiovascular and Hypertension Center and the University of Oklahoma School of Medicine, Oklahoma City, Oklahoma 73132, USA
    Am J Hypertens 17:590-6. 2004
    Most patients with hypertension require two or more antihypertensive medications to achieve blood pressure (BP) goals...
  76. ncbi Cardiorenal protective effects of year-long antihypertensive therapy with an angiotensin-converting enzyme inhibitor or a calcium channel blocker in spontaneously hypertensive rats
    Toshihiko Ishimitsu
    Department of Hypetension and Cardiorenal Medicine, Dokkyo Medical University, Mibu, Tochigi, Japan
    Am J Hypertens 19:1233-40. 2006
    ..The objective of this study was to evaluate the effect of year-long antihypertensive therapy with a calcium channel blocker and an angiotensin-converting enzyme (ACE) inhibitor on cardiac and renal injury...
  77. ncbi Ovariectomy augments hypertension through rho-kinase activation in the brain stem in female spontaneously hypertensive rats
    Koji Ito
    Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan
    Hypertension 48:651-7. 2006
    ....
  78. ncbi Cardiovascular excitatory effect on rats of a fraction isolated from the eyestalk of shrimp: Peneaus vanameii
    Francisco Rosa
    Departamento de Ciencias Fisiologicas, Escuela de Ciencias de la Salud, Nucleo Bolivar, Universidad Central de Venezuela, Caracas
    Invest Clin 47:133-41. 2006
    ..2 mL) reduced the effect of CES on mean blood pressure, but not on heart rate. Propranolol pretreatment (4 microg/0...
  79. ncbi Effects of nine antihypertensive drugs on blood pressure variability in sinoaortic-denervated rats
    Jin Wang
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 27:1013-7. 2006
    AIM: The present work was designed to investigate the effects of nine commonly used antihypertensive drugs on blood pressure (BP) and blood pressure variability (BPV) in conscious sinoaortic-denervated (SAD) rats...
  80. ncbi Effects of angiotensin II type 1 receptor blockade on the systemic blood nitric oxide dynamics in Nomega-nitro-L-arginine methyl ester-treated rats
    Yasuhisa Kanematsu
    Department of Pharmacology, Institute of Health Biosciences, The University of Tokushima Graduate School of Medical Sciences, Japan
    Hypertens Res 29:369-74. 2006
    ..In conclusion, our findings suggested that chronic administration of olmesartan ameliorated the endothelial dysfunction in L-NAME-treated rats...
  81. ncbi Effects of the angiotensin receptor blocker candesartan on arterial stiffness and markers of extracellular matrix metabolism in patients with essential hypertension
    Hiroyuki Sasamura
    Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
    Clin Exp Hypertens 28:511-20. 2006
    ..e., after achieving blood pressure reduction) and one year after the initiation of therapy...
  82. ncbi Antihypertensive responses elicited by central moxonidine in rats: possible role of nitric oxide
    Thiago Santos Moreira
    Department of Physiology, , 04023-060, , Brazil
    J Cardiovasc Pharmacol 47:780-7. 2006
    ..Therefore, these data indicate that nitric oxide mechanisms are involved in hypotension and mesenteric, renal, and hindquarter vasodilation induced by central moxonidine in normotensive and in acute hypertensive rats...
  83. ncbi Angiotensin II type 1 receptor blocker prevents atrial structural remodeling in rats with hypertension induced by chronic nitric oxide inhibition
    Hidetoshi Okazaki
    Department of Structural Analysis, National Cardiovascular Center Research Institute, Suita, Japan
    Hypertens Res 29:277-84. 2006
    ..Eight weeks after treatment, the L-NAME group showed significantly higher systolic blood pressure than the control group (197 +/- 12 vs.138 +/- 5 mmHg, p < 0.05)...
  84. ncbi Calcium channel blockades exhibit anti-inflammatory and antioxidative effects by augmentation of endothelial nitric oxide synthase and the inhibition of angiotensin converting enzyme in the N(G)-nitro-L-arginine methyl ester-induced hypertensive rat aorta
    Hiroe Toba
    Department of Clinical Pharmacology, Kyoto Pharmaceutical University, Kyoto, Japan
    Hypertens Res 28:689-700. 2005
    ..To investigate the vasoprotective effects beyond the blood pressure-lowering effects of these agents, amlodipine (20 mg/kg/ day) and manidipine (10 mg/kg/day) were administered ..
  85. ncbi Central actions of agmatine in conscious spontaneously hypertensive rats
    S Briaud
    Institut de Recherche Neurologique et Cardiovasculaire, , Tours, France
    Clin Exp Hypertens 27:619-27. 2005
    ..Agmatine, when administered in low doses (30-100 microg/kg) into the fourth ventricle had no effect on blood pressure and caused an increase in heart rate...
  86. ncbi Neuroprotective effects of candesartan against cerebral ischemia in spontaneously hypertensive rats
    Qing Lu
    Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Neuroreport 16:1963-7. 2005
    ....
  87. ncbi Role of the renal nerves in gamma-aminobutyric acid-induced antihypertensive effect in spontaneously hypertensive rats
    Kazuhito Hayakawa
    Yakult Central Institute for Microbiological Research, Kunitachi shi, Tokyo, Japan
    Eur J Pharmacol 524:120-5. 2005
    ..These results suggest that a reduction in the effects induced by the renal nerves may play an important role in the hypotensive effect induced in spontaneously hypertensive rats by chronic dietary administration of GABA...
  88. ncbi Attenuated pressor responses to amino acids in the rostral ventrolateral medulla after swimming training in conscious rats
    Marli Cardoso Martins-Pinge
    Department of Physiological Sciences, Center of Biological Sciences, State University of Londrina, Londrina, Parana, Brazil
    Auton Neurosci 122:21-8. 2005
    ..These findings suggest that RVLM is involved in the modulation of the sympathetic outflow to the cardiovascular system during exercise training...
  89. ncbi Increased expression of gp91phox homologues of NAD(P)H oxidase in the aortic media during chronic hypertension: involvement of the renin-angiotensin system
    Takashi Akasaki
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertens Res 29:813-20. 2006
    ..5 mg/kg/day). The high-dose candesartan or the hydralazine plus hydrochlorothiazide decreased the blood pressure of SHRSP to that of WKY, whereas the low-dose candesartan exerted no significant antihypertensive action...
  90. ncbi Neonatal chemical sympathectomy attenuates fructose-induced hypertriglyceridemia and hypertension in rats
    P S Hsieh
    Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan, ROC
    Chin J Physiol 44:25-31. 2001
    ..Both groups of rats were fed a fructose-enriched diet for 9 weeks. The systolic blood pressure (SBP) and body weight were measured weekly and arterial blood samples were taken weekly for determinations of ..
  91. ncbi Atorvastatin causes depressor and sympatho-inhibitory effects with upregulation of nitric oxide synthases in stroke-prone spontaneously hypertensive rats
    Takuya Kishi
    Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    J Hypertens 21:379-86. 2003
    OBJECTIVE: Recent studies have suggested that statins decrease blood pressure in hypertensive animals and upregulate endothelial nitric oxide synthase (eNOS) expression...
  92. ncbi Downregulation of basal iNOS at the rostral ventrolateral medulla is innate in SHR
    Julie Y H Chan
    Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, Republic of China
    Hypertension 41:563-70. 2003
    ..hypertensive rats (SHR) treated for 4 weeks with the antihypertensive captopril to normalize elevated blood pressure or in young prehypertensive SHR, the significantly lower iNOS mRNA and protein levels at the ventrolateral ..
  93. ncbi Antihypertensive action and blockade of alpha1-adrenoceptors by DL-017, a quinazoline derivative
    L M Tsai
    Department of Physiology and Biophysics, National Defense Medical Center, National Defense University, Taipei, Taiwan
    J Cardiovasc Pharmacol 38:893-9. 2001
    ..Intravenous administration of DL-017 induced dose-dependent reductions of heart rate and blood pressure, which persisted over 2 h. DL-017 exerted a maximal antihypertensive effect at 0...
  94. ncbi Heart rate and pulse pressure amplification in hypertensive subjects
    Pierre Laurent
    Department of Internal Medicine, Broussais Hospital, Paris, France
    Am J Hypertens 16:363-70. 2003
    BACKGROUND: Although mean blood pressure (MBP) remains unmodified along the arterial tree, pulse pressure (PP) increases physiologically from the central to the peripheral arteries...
  95. ncbi Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats
    Mohamed A Bayorh
    Department of Pharmacology and Toxicology, Morehouse School of Medicine, Atlanta, Georgia 30310 1495, USA
    Am J Hypertens 16:387-92. 2003
    ....
  96. ncbi Antihypertensive therapy with verapamil SR plus trandolapril versus atenolol plus chlorthalidone on glycemic control
    Heinrich Holzgreve
    Medizinische Poliklinik HH, University of Munich, Munich, Germany
    Am J Hypertens 16:381-6. 2003
    ....
  97. ncbi Enhanced angiotensin-mediated responses in the nucleus tractus solitarii of spontaneously hypertensive rats
    Nobuhide Katsunuma
    Second Department of Internal Medicine, Nihon University School of Medicine, 30-1, Oyaguchi-Kamichou, Itabashi-ku, Tokyo 173-8610, Japan
    Brain Res Bull 60:209-14. 2003
    ..Thus, stimulation of AT(1) receptors within the NTS contributes to cardiovascular regulation independently of the baroreceptor reflex and the glutamatergic system. This angiotensinergic system in SHR acts tonically to reduce AP...
  98. ncbi [Depressive effect of total flavonoid fraction of Asttragalus complanatus R. Br and its influence upon hemodynamics in SHR]
    Bing Xue
    Department of Pathophysiology, School of Medicine, Shandong University, Jinan, 250012, Shandong, China
    Zhongguo Zhong Yao Za Zhi 27:855-8. 2002
    OBJECTIVE: To investigate effects of total flavonoid fraction of Asttragalus complanatus on blood pressure in conscious spontaneously hypertensive rats(SHR) and hemodynamics in anesthetized SHR...
  99. ncbi Determinants of ambulatory blood pressure response to physical activity
    Marinel Cavelaars
    Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
    J Hypertens 20:2009-15. 2002
    ..that the association between physical activity, measured with a wrist-worn accelerometer, and ambulatory blood pressure is rather weak and that the inter-individual variation in the degree of association is high...
  100. ncbi Effects of chronic treatment with cromakalim and glibenclamide in alloxan-induced diabetic rats
    Jayant S Kulkarni
    Cadila Pharmaceuticals, Dholka, Ahmedabad 387810, India
    Pharmacol Res 46:101-5. 2002
    ..Injection of alloxan (60 mg kg(-1)/i.v., single dose) produced a significant increase in the blood pressure, bradycardia, hyperglycemia, hypoinsulinemia, hyperlipidemia, hypothyroidism and depression in left ..
  101. ncbi Local administration of ETA (but not ETB) blockers into the PAG area of the brain decreases blood pressure of DOCA-salt rats
    Clara Di Filippo
    Department of Experimental Medicine, Section of Pharmacology L. Donatelli, Research Center for Cardiovascular Diseases, Faculty of Medicine and Surgery, Second University of Naples, Via Costantinopoli 16, Italy
    Naunyn Schmiedebergs Arch Pharmacol 366:123-6. 2002
    ..possibly played by ET-receptor antagonism at periaqueductal grey (PAG) area level in decreasing the arterial blood pressure and heart rate values reached in DOCA-salt hypertensive rats...

Research Grants80

  1. FETAL REFLEX RESPONSES TO CEREBRAL HYPOPERFUSION
    Charles Wood; Fiscal Year: 1999
    Fetal sheep respond to hypotension with reflex hormonal and hemodynamic responses which return blood pressure to normal levels...
  2. Mechanims of CNS Autonomic Regulation by EA
    John C Longhurst; Fiscal Year: 2010
    ..Small trails further suggest that EA can lower elevated blood pressure. Studies conducted in the last two grant cycles have evaluated supra-spinal mechanisms underlying EA's ..
  3. The baroreflex in pregnancy: effects of adrenal and placental steroids
    Maureen Keller Wood; Fiscal Year: 2009
    ..This model also causes reduced fetal blood pressure and increased incidence of fetal hypoxia and fetal and maternal death...
  4. The baroreflex in pregnancy: effects of adrenal and placental steroids
    Maureen Keller Wood; Fiscal Year: 2010
    ..This model also causes reduced fetal blood pressure and increased incidence of fetal hypoxia and fetal and maternal death...
  5. Older Mothers and Adult Daughters: High Blood Pressure Self Management Behaviors
    Celeste Shawler; Fiscal Year: 2010
    ..strength, perceived control, and the quality of the relationship of older mothers and their adult daughters on blood pressure self management behaviors and health related quality of life...
  6. Older Mothers and Adult Daughters: High Blood Pressure Self Management Behaviors
    Celeste Shawler; Fiscal Year: 2009
    ..strength, perceived control, and the quality of the relationship of older mothers and their adult daughters on blood pressure self management behaviors and health related quality of life...
  7. Chicago Endothelial Function Study
    LOUISE HAWKLEY; Fiscal Year: 2009
    _' High blood pressure is a strong, modifiable, independent risk factor for cardiovascular and renal disease, and was a primary or contributing cause of 11% of U.S. deaths in 2003 (American Heart Association, 2006)...
  8. Chicago Endothelial Function Study
    Louise C Hawkley; Fiscal Year: 2010
    _' High blood pressure is a strong, modifiable, independent risk factor for cardiovascular and renal disease, and was a primary or contributing cause of 11% of U.S. deaths in 2003 (American Heart Association, 2006)...
  9. IINFLUENCE OF INSULIN ON BLOOD PRESSURE CHANGE DURING AD
    Alan Sinaiko; Fiscal Year: 1999
    The primary objective of this research project is to define the relation of insulin resistance to blood pressure in children and to changes in blood pressure that occur during adolescence...
  10. CONTROL OF VASCULAR TONE BY CONTINGENT CNS STIMULATION
    Barry Dworkin; Fiscal Year: 2006
    ..by the applicant): These multi-disciplinary studies target the long-sought physiological link between blood pressure variability and blood pressure regulation...
  11. The Renal Medulla and Hypertension
    David Stec; Fiscal Year: 2009
    This project will test the central hypothesis that increased HO-1 in the renal medulla lowers blood pressure in angiotensin II (Ang II) hypertension by inhibiting Ang II induced increases in NADPH oxidase and superoxide production via ..
  12. The Renal Medulla and Hypertension
    David E Stec; Fiscal Year: 2010
    This project will test the central hypothesis that increased HO-1 in the renal medulla lowers blood pressure in angiotensin II (Ang II) hypertension by inhibiting Ang II induced increases in NADPH oxidase and superoxide production via ..
  13. Genotypes, Haplotypes, and Blood Pressure Change from Childhood to Adulthood
    DAVID MICHAEL HALLMAN; Fiscal Year: 2010
    ..While hypertension is found in <10% in adults 20 - 34 years of age, it develops over a period of years, and blood pressure levels in children and adolescents are correlated with levels in adults...
  14. Genotypes, Haplotypes, and Blood Pressure Change from Childhood to Adulthood
    DAVID HALLMAN; Fiscal Year: 2009
    ..While hypertension is found in <10% in adults 20 - 34 years of age, it develops over a period of years, and blood pressure levels in children and adolescents are correlated with levels in adults...
  15. Paraventricular nucleus regulatory mechanisms in stress and hypertension
    COLIN contact SUMNERS; Fiscal Year: 2010
    It is established that the central nervous system (CNS) contributes to the long-term regulation of blood pressure in both health and disease via effects on neuroendocrine mechanisms and sympathetic outflow...
  16. Mechanisms of Meditation in Hypertension in Blacks
    Robert Schneider; Fiscal Year: 2010
    ..Previous randomized controlled trials in African American populations with high blood pressure conducted by the Center team have demonstrated that stress reduction intervention with the Transcendental ..
  17. Mechanisms of Meditation in Hypertension in Blacks
    Robert Schneider; Fiscal Year: 2007
    ..Previous randomized controlled trials in African American populations with high blood pressure conducted by the Center team have demonstrated that stress reduction intervention with the Transcendental ..
  18. Mechanisms of Meditation in Hypertension in Blacks
    Robert Schneider; Fiscal Year: 2009
    ..Previous randomized controlled trials in African American populations with high blood pressure conducted by the Center team have demonstrated that stress reduction intervention with the Transcendental ..
  19. Angiotensin: A Link Between Obesity and Hypertension
    Lisa Cassis; Fiscal Year: 2007
    ..fat diet (MHF) stimulates the adipose renin-angiotensin system, contributing to obesity-related elevations in blood pressure. Preliminary data demonstrates that rats fed a MHF diet segregate into obesity prone (OP) versus obesity-..
  20. Behavioral and Physiological Responses to Race-Related Stress in Diabetic Women
    Julie Wagner; Fiscal Year: 2007
    ..The stress of exposure to discrimination may contribute to altered blood pressure, glycemia, insulin resistance, and self-care behaviors, thereby increasing risk for complications...
  21. VESTIBULAR INFLUENCES ON THE SYMPATHETIC NERVOUS SYSTEM
    Bill Yates; Fiscal Year: 2003
    ..Abstract) Research over the past decade has demonstrated that the vestibular system influences the control of blood pressure, both in humans and in animal models...