hemodynamic phenomena

..4 These data suggest that miglitol reduces myocardial apoptosis by attenuating production of hydroxyl radicals and suppressing the upregulation of the expression of Bax protein...

..5 These results demonstrate that blocking the JNK pathway may represent a novel therapeutic approach for treating myocardial ischemia/reperfusion-induced cardiomyocyte death...

..A slow wave of PMN accumulation at late R may be involved in the extension of infarction and endothelial dysfunction...

..The purpose of the present study was to assess prospectively the systemic and renal hemodynamic and tubular responses to salt in women taking oral contraceptives...

..CONCLUSIONS: Telmisartan effectively blocked the effects of intravenous Ang II on CI, BP, RI and SI in healthy volunteers. Changes in CI make a major contribution to increase in BP response to intravenous Ang II in normal volunteers...

..Head-up tilting decreases the CBV less in patients with cirrhosis, and the results suggest a differential regulation of central hemodynamics in patients with cirrhosis...

..The effect is independent of infarct size or afterload reduction, indicating a direct effect on the myocardium...

..This model is therefore suitable to study myocardial repair after injury...

..However, the density of the beta-adrenoceptor in the viable ischemic regions can be modified by the presence of GRK2 and tissue catecholamines, an index of regional sympathetic efferent postganglionic nerve terminal activity...

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..The present study suggests that meluadrine tartrate has a mild influence relative to the effects of ritodrine to the maternal metabolic responses and fetal cardiovascular function...

..Thus a stressful stimulus that resulted in cardiovascular changes similar to those seen during freezing behavior enhanced defense of arterial pressure during hemorrhage...

..However, the involvement of endothelin (ET) in this disease process is yet unknown...

..Quinaprilat reduces myocardial infarct size involving NO production and mitochondrial KATP channels in rabbits without collateral circulation...

..3+/-2.5% (P<0.01). Intravenous atenolol and esmolol, independent of timing and mode of administration, does not seem to interfere with protection afforded by ischemic preconditioning in vivo...

..This occurs despite rapid resolution of infection and is associated with an extremely poor prognosis...

..Incomplete PARP inhibition because of dilutional effects and/or an only partial efficacy when used in post-treatment approaches may account for this finding...

..In this study, the effect of TVE on cryosurgical ablation of liver tissue close to the retrohepatic vena cava was investigated with regard to the extent of the cryolesion and complications arising from necrosis of the caval wall...

..We conclude that NO tonically regulates epoxygenase activity and that EETs are renal vaosoconstrictors in vivo and contribute, at least in part, to the renal functional responses following inhibition of NO production...

..The association of AF with a higher incidence of sudden death may be due to an enhanced electrical instability...

..In addition to its beta-adrenergic receptor blockage, antiapoptotic effects have been demonstrated in experimental animals...

..However, the development and regression of pulmonary hypertension and RVH were related to the expression of some PKC isoforms suggesting that pathways other than alpha(1)-AR might be involved in hypoxia-induced ventricular hypertrophy...

..Our novel findings of increased cardiac CNTF and cardiopulmonary MCP-1 mRNA indicate a role for these factors in the pathogenesis of HF...

..These findings suggest that Etr-evoked improvements in coronary function are maintained in small arteries even when exposed to ischemia and reperfusion...

..The aim of the present study was to test whether an analogous leptin effect on glucose transport is detectable in the heart...

..CONCLUSIONS: Simvastatin administration increases the hepatosplanchnic output of nitric oxide products and decreases hepatic resistance in patients with cirrhosis...

..To evaluate the hemodynamics in patients with traumatic brain injury (TBI) during therapeutic hypothermia...

..05 microg x kg(-1) x min(-1) group. CONCLUSIONS: We conclude that the low-dose infusion of hANP in the recipients of renal transplantation is useful for the optimal anesthetic care because of the cardiovascular improvement...

..These results suggest that cardiac overloading and left ventricular remodeling are decreased more by stenting than by POBA alone, probably because stenting prevents decreased myocardial blood flow around the infarct myocardium...

..SIM beneficially affects autonomic tone in CHF as seen by the reversal of depressed HRV and total power of PSA. These data have important implications for the treatment of patients with autonomic imbalance...

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..These results suggest that PC-induced reduction of GJ permeability during ischemia, presumably by PKC-mediated Cx43 phosphorylation, contributes to infarct size limitation...

..Compound 14 showed approximately 5-fold greater selectivity than 1 in vivo and supports the concept that bladder-selective K(ATP) channel openers may have utility in the treatment of overactive bladder...

..CONCLUSION: These findings indicate that continuous PGE1 infusion through the SMA may prove useful in clinical settings to prevent liver damage after HAO...

..The purpose of this study was to provide a detailed morphological evaluation of intestinal surface epithelium after aortic cross-clamping...

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..We conclude that better surfactant distribution achieved by lavage administration can be more effective than bolus administration in this type of non-homogeneous lung injury...

..Hemodynamic, biological and radiological results are similar to those observed in clinical free-islet transplantation...

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..To conclude, a fast beta2 agonist-mediated local release of t-PA into the coronary vasculature was demonstrated. For total t-PA, this response was characterised by a biphasic release profile...

..implicit reliability and reproducibility of the experiments, provided that they are able to reproduce both hemodynamic phenomena and energetic relationships...

..and septomarginal trabecula are common elements of the right ventricle, and determine many hemodynamic phenomena. The morphological analysis of both structures in regard to their mutual relations was the aim of this ..

..The large model exhibits better and more regular hemodynamic phenomena and may be effective in decreasing the probability of the initiation and development of postoperative ..

..These predictions have significant implications for understanding the local hemodynamic phenomena that may contribute to the earliest stage of atherosclerosis, as clinically observed on the inside ..

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..Patent ductus arteriosus (PDA) is a common complication in preterm infants. While two-dimensional echocardiography is the method of choice for diagnosing a PDA, clinical signs are known to be of limited value...

..However, data from the long-term use of COMT inhibitors are needed to confirm these findings...

..CONCLUSIONS: Ultrasound-mediated microbubble destruction may enable myocardial HGF gene transfer with systemic administration of naked plasmid, which enhances angiogenesis, limits infarction size, and prevents LV remodeling after MI...

..In general, the large model exhibits better and more uniform hemodynamic phenomena near the vessel wall and may be effective in preventing the initiation and development of postoperative ..

..All compounds studied showed greater potency to inhibit spontaneous bladder contractions relative to their potencies to inhibit contractions elicited by electrical stimulation...

..are used to identify the normal and the pathological morphology of the valvular segment, and the hemodynamic phenomena occurring at this level...

..CONCLUSION: This study suggests that GSNO can appropriately donate NO to suppress platelet activation and platelet iNOS induction, resulting in less platelet activation, better blood perfusion, and flap survival after I/R injury...

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..These results demonstrate that the alpha 1 isoform regulates cardiac contractility, and that both the alpha 1 and alpha 2 isoforms are functionally and physically coupled with the Na/Ca exchanger in heart...

..At present, it has become crucial to understand the characteristics and clinical implications of these BP measuring techniques for those responsible for the care of hypertensive patients...

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..In contrast, the pulmonary circulation was relatively unresponsive to BK...

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..These results suggest that reactive oxygen species play a role in the regulation of peripheral sympathetic nerve activity, and that at least part of this mechanism is mediated through voltage-gated potassium channels...

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..Our aim was to assess the hemodynamic effects of terlipressin and high somatostatin dose during acute variceal bleeding in nonresponders to the usual somatostatin dose...

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..The results indicate that the hemodynamic effects of i.v. hUCN2, mUCN2, and CRF depend on activation of CRF(2) receptors and do not involve NO or prostanoids...

..0001). CONCLUSIONS: Mothers of SGA fetuses show hemodynamic features similar to those with physiological pregnancies suggesting that their fetuses are likely to be constitutionally small and not pathologically growth-restricted...

..The consistent failure of PGI2 to elicit pulmonary vasodilation in this study suggests fundamental differences in AA metabolism or the etiology of pulmonary hypertension may exist when broilers are compared with mammals...

..Finally, well-known and potential therapeutic strategies targeting each system are discussed, ending with an overall conclusion...

Contradictory reports on the significance of several hemodynamic phenomena, such as femoral vein incompetence and incompetent calf perforators, impede orientation in venous hemodynamics...

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..Understanding the role of hemodynamics in atherogenesis may lead to the improvement of minimally invasive endovascular therapy and noninvasive strategies...

..Thus genetic overexpression of eNOS in mice attenuates myocardial infarction after MI/R but fails to significantly protect against postischemic myocardial contractile dysfunction in mice...

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..CONCLUSIONS: A continuous infusion of remifentanil allowed optimal control of surgical stress and a return to preoperative status and ventilatory settings without side-effects...

..The increase in MMP-9 activity is associated with endocardial endothelial apoptosis and dysfunction in diabetes mellitus...

..The aim of this study was to investigate both the hemodynamic profile and the clinical consequences of plateau waves...

..CONCLUSION: This is the first successful case of cellular cardiomyoplasty without any conjunctional procedure for patient with severe coronary heart disease and heart failure...

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..Our data demonstrate that, in contrast to NE, administration of AVP effectively restores renal blood flow and Do2 with comparable systemic and splanchnic hemodynamic and metabolic effects in endotoxin-induced circulatory shock...

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..An impaired hemodynamic response to nitric oxide synthesis inhibition in diabetes is therefore not caused by a primary defect but rather due to altered vascular responsiveness secondary to long-standing disease...

..In particular, there are cases of pure geometric ED which, potentially, is surgically curable. These cases should not be erroneously labelled as psychogenic cases...

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..The lack of response to ET-A receptor blockade suggests that the beneficial effect of ET receptor antagonists in this model is likely to be due to improvement of renal morphology...

..banding-induced deterioration of LV systolic function is associated with LV eccentric remodelling and (iii) the antihypertrophic effect of propranolol is due to a selective action on cardiomyocytes rather than on collagen accumulation..

..The extent of these interactions is dependent on the duration of ischemia, but not on reperfusion time. Adherent platelets seem to participate in the development of sinusoidal perfusion failure in the postischemic liver...

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..This novel model offers a robust, clinically relevant, statistically powerful small animal model for evaluation of high- and low-shear-regulated VG remodeling...

..The most important studies of the long-term treatment of stable cardiac failure with pimobendan and on the short-term treatment of unstable cardiac failure with levosimendan are presented...

..However, the increases in postsinusoidal resistance and Pdo cause hepatic congestion. Endogenously produced NO, but not CO, modulates these responses...

..3 +/- 11.1 to 66.2 +/- 10.8 pmol/10(5) cells). CONCLUSION: The stimulatory effect of uremic plasma on endothelial NO synthesis was augmented during dialysis-37.5 degrees C but not during cool dialysis...

..These grafts are prone to the development of stenosis in the vein due to intimal hyperplasia, subsequently leading to thrombosis and graft failure...

..These results suggest that olprinone hydrochloride 15 micrograms.kg-1 bolus plus 0.1 microgram.kg-1.min-1 continuous administration may be effective for improvement of hemodynamics and peripheral circulation after CPB...

..In vitro studies suggest that these hemodynamic responses are related to direct modulation of the vascular tone...

..The proposed technique is especially suitable for observations of the microcirculation under intravital fluorescence microscopy...

..The accuracy of SpaceLabs 90207 is altered by venous blood redistribution. These inaccuracies may constitute an additional limitation of oscillometric ambulatory BP monitoring...

..Thus atrial wall stress from contraction during ventricular systole even for a short period of time modifies atrial electrophysiology. Deficient AV synchrony may immediately contribute to the development of atrial arrhythmias...

..To investigate clinical features of pheochromocytoma and summarize experiences of anesthetic management during the perioperative period...

..In contrast, HR in KS-mut animals did not change after either treatment. Except for cardiac hypertrophy, the presence of a germline TR-beta mutation had surprisingly little effect on cardiac function...

..CONCLUSION: The present study demonstrates the potential role of mitochondrial PTP after long- time hypothermic preservation of the heart, and therefore, regulation of PTP would prolong the preservation time of donor hearts...

..Practical training for aircrew, and research on clinically relevant hypoxic conditions frequently rely exclusively on large, expensive hypobaric chambers...

..The long-term objective of this project is to apply DOI to the study of normal brain development in infants, and to the diagnosis and follow-up of cerebrovascular diseases and psychiatric syndromes in adults and children. ..

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