collateral circulation

Summary

Summary: Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.

Top Publications

  1. ncbi A new hypothesis of the developmental origin of congenital left anterior descending coronary artery to pulmonary artery fistulas
    Lloyd W Klein
    Rush Medical College, Chicago, Illinois, USA
    Catheter Cardiovasc Interv 71:568-71. 2008
  2. ncbi Endothelium-dependent relaxation of collateral microvessels after intramuscular gene transfer of vascular endothelial growth factor in a rat model of hindlimb ischemia
    S Takeshita
    Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan
    Circulation 98:1261-3. 1998
  3. ncbi Congenital absence of the internal carotid artery: case reports and review of the collateral circulation
    C A Given
    Department of Neuroradiology, Wake Forest University Baptist Medical Center, Winston-Salem, NC 27157, USA
    AJNR Am J Neuroradiol 22:1953-9. 2001
  4. ncbi Carotid artery occlusion and collateral circulation in C57Black/6J mice detected by synchrotron radiation microangiography
    Masahiro Tamaki
    Department of Neurosurgery, Kobe University Graduate School of Medicine
    Kobe J Med Sci 52:111-8. 2006
  5. ncbi Microvascular remodeling and accelerated hyperemia blood flow restoration in arterially occluded skeletal muscle exposed to ultrasonic microbubble destruction
    Ji Song
    Dept. of Biomedical Engineering, Univ. of Virginia, Box 800759, UVA Health System, Charlottesville, VA 22908, USA
    Am J Physiol Heart Circ Physiol 287:H2754-61. 2004
  6. ncbi Therapeutic angiogenesis induced by controlled release of fibroblast growth factor-2 from injectable chitosan/non-anticoagulant heparin hydrogel in a rat hindlimb ischemia model
    Masanori Fujita
    Department of Medical Engineering, National Defense Medical College, Saitama, Japan
    Wound Repair Regen 15:58-65. 2007
  7. ncbi Venous collateral circulation of the extracranial cerebrospinal outflow routes
    Paolo Zamboni
    Vascular Diseases Center, University of Ferrara, Ferrara, Italy
    Curr Neurovasc Res 6:204-12. 2009
  8. ncbi Relationship between pressure-derived collateral blood flow and diabetes mellitus in patients with stable angina pectoris: a study based on coronary pressure measurement
    Yilmaz Nisanci
    Istanbul University, Istanbul Faculty of Medicine, Department of Cardiology, Istanbul, Turkey
    J Invasive Cardiol 14:118-22. 2002
  9. ncbi Conduction performance of collateral vessels induced by vascular endothelial growth factor or basic fibroblast growth factor
    Keisuke Kondoh
    Department of Vascular Regeneration, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Cardiovasc Res 61:132-42. 2004
  10. ncbi Humoral and cellular factors responsible for coronary collateral formation
    Jonathan A Sherman
    Section of Cardiology, Department of Medicine, Dartmouth Medical School, Lebanon, New Hampshire, USA
    Am J Cardiol 98:1194-7. 2006

Research Grants

  1. Quantifying Collateral Perfusion in Cerebrovascular Disease
    GREGORY ZAHARCHUK; Fiscal Year: 2009
  2. Quantifying Collateral Perfusion in Cerebrovascular Disease
    GREGORY GEORGE ZAHARCHUK; Fiscal Year: 2010
  3. Reactive Oxygen Species in Coronary Collateral Growth
    WILLIAM CHILIAN; Fiscal Year: 2009
  4. Reactive Oxygen Species in Coronary Collateral Growth
    William M Chilian; Fiscal Year: 2010
  5. EFFECT OF DRUGS UPON MYOCARDIAL HYPOXIA
    Garrett Gross; Fiscal Year: 1993
  6. PEROXYLIPIDS/NITRIC OXIDE IN THROMBOTIC STROKE
    Brant Watson; Fiscal Year: 1993
  7. Stem cell-based therapy in heart failure: aging effects
    Mohamed Gaballa; Fiscal Year: 2003
  8. Exercise, Antioxidants, and I-R Injury
    Scott Powers; Fiscal Year: 2006
  9. Collateral Circulation in Acute Ischemic Stroke
    David Liebeskind; Fiscal Year: 2007
  10. HYPOXIA INDUCIBLE VEGF PRODUCTION IN SLEEP APNEA
    Andrew Levy; Fiscal Year: 2003

Detail Information

Publications186 found, 100 shown here

  1. ncbi A new hypothesis of the developmental origin of congenital left anterior descending coronary artery to pulmonary artery fistulas
    Lloyd W Klein
    Rush Medical College, Chicago, Illinois, USA
    Catheter Cardiovasc Interv 71:568-71. 2008
    ....
  2. ncbi Endothelium-dependent relaxation of collateral microvessels after intramuscular gene transfer of vascular endothelial growth factor in a rat model of hindlimb ischemia
    S Takeshita
    Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan
    Circulation 98:1261-3. 1998
    ..The purpose of this study was to determine in vivo the extent to which vasomotor responses of collateral microvessels are altered after VEGF treatment...
  3. ncbi Congenital absence of the internal carotid artery: case reports and review of the collateral circulation
    C A Given
    Department of Neuroradiology, Wake Forest University Baptist Medical Center, Winston-Salem, NC 27157, USA
    AJNR Am J Neuroradiol 22:1953-9. 2001
    ..Recognition of this anomaly has important implications during planned carotid or transsphenoidal surgery, in thromboembolic disease, and in the surveillance and detection of associated cerebral aneurysms...
  4. ncbi Carotid artery occlusion and collateral circulation in C57Black/6J mice detected by synchrotron radiation microangiography
    Masahiro Tamaki
    Department of Neurosurgery, Kobe University Graduate School of Medicine
    Kobe J Med Sci 52:111-8. 2006
    ..We could successfully visualize the cerebral vasculature of normal mice and carotid artery occluded mice in an in vivo study. Microangiography can demonstrate the development of vasculature and the blood flow dynamics in mice...
  5. ncbi Microvascular remodeling and accelerated hyperemia blood flow restoration in arterially occluded skeletal muscle exposed to ultrasonic microbubble destruction
    Ji Song
    Dept. of Biomedical Engineering, Univ. of Virginia, Box 800759, UVA Health System, Charlottesville, VA 22908, USA
    Am J Physiol Heart Circ Physiol 287:H2754-61. 2004
    ..We conclude that ultrasonic microbubble destruction can be tailored to stimulate an arteriogenesis response that restores hyperemia blood flow to skeletal muscle in a rat model of arterial occlusion...
  6. ncbi Therapeutic angiogenesis induced by controlled release of fibroblast growth factor-2 from injectable chitosan/non-anticoagulant heparin hydrogel in a rat hindlimb ischemia model
    Masanori Fujita
    Department of Medical Engineering, National Defense Medical College, Saitama, Japan
    Wound Repair Regen 15:58-65. 2007
    ..These results indicate that the controlled release of biologically active FGF-2 molecules from FGF-2/CH-LA/IO4-heparin induces angiogenesis and possibly collateral circulation in db/db mice and the ischemic limbs of rats.
  7. ncbi Venous collateral circulation of the extracranial cerebrospinal outflow routes
    Paolo Zamboni
    Vascular Diseases Center, University of Ferrara, Ferrara, Italy
    Curr Neurovasc Res 6:204-12. 2009
    ..We review the complex gross and radiological anatomy of collateral circulation found activated by the means of EchoColor-Doppler and selective venography in the event of CCSVI, focusing ..
  8. ncbi Relationship between pressure-derived collateral blood flow and diabetes mellitus in patients with stable angina pectoris: a study based on coronary pressure measurement
    Yilmaz Nisanci
    Istanbul University, Istanbul Faculty of Medicine, Department of Cardiology, Istanbul, Turkey
    J Invasive Cardiol 14:118-22. 2002
    ..Coronary angiography, the most commonly used technique for studying collateral circulation, may not be accurate in assessing collateral circulation because most collaterals are situated ..
  9. ncbi Conduction performance of collateral vessels induced by vascular endothelial growth factor or basic fibroblast growth factor
    Keisuke Kondoh
    Department of Vascular Regeneration, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Cardiovasc Res 61:132-42. 2004
    ....
  10. ncbi Humoral and cellular factors responsible for coronary collateral formation
    Jonathan A Sherman
    Section of Cardiology, Department of Medicine, Dartmouth Medical School, Lebanon, New Hampshire, USA
    Am J Cardiol 98:1194-7. 2006
    ..Rather, cellular properties, such as cell adhesion, or genetic differences between patients may be the driving force for collateral development...
  11. ncbi Association between the dosage and duration of statin treatment with coronary collateral development
    Irem Dincer
    Ankara University Faculty of Medicine, Dikmen, Ankara, Turkey
    Coron Artery Dis 17:561-5. 2006
    The coronary collateral circulation is an alternative source of blood supply to myocardium in the presence of advanced coronary artery disease and the therapeutic promotion of collateral growth appears to be a valuable treatment strategy ..
  12. ncbi Prognostic significance of coronary collaterals in patients with coronary heart disease having percutaneous transluminal coronary angioplasty
    Jeroen Koerselman
    Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands
    Am J Cardiol 96:390-4. 2005
    ..In patients with ischemic heart disease, the angiographic presence of coronary collaterals may mark an unfavorable prognosis, particularly in relatively high-risk patients...
  13. ncbi Coronary collateral circulation: effect on early and midterm outcomes after off-pump coronary artery bypass surgery
    Massimo Caputo
    Bristol Heart Institute, Bristol Royal Infirmary, Bristol, United Kingdom
    Ann Thorac Surg 85:71-9. 2008
    ..The purpose of this study was to assess the prognostic effect of coronary collaterals on early and midterm clinical outcomes in patients undergoing first time isolated off-pump coronary artery bypass (OPCAB) surgery...
  14. ncbi Impact of coronary collaterals on outcome following percutaneous coronary intervention (from the National Heart, Lung, and Blood Institute Dynamic Registry)
    J Dawn Abbott
    Division of Cardiology, Brown University, Rhode Island Hospital, Providence, Rhode Island, USA
    Am J Cardiol 96:676-80. 2005
    Coronary collateral circulation is beneficial in patients with coronary artery disease, but controversy still exists regarding the association between angiographic collaterals and outcome after percutaneous coronary intervention (PCI)...
  15. ncbi Collateral circulation via the ophthalmic artery or leptomeningeal vessels is associated with impaired cerebral vasoreactivity in patients with symptomatic carotid artery occlusion
    J Hofmeijer
    University Department of Neurology, University Medical Center Utrecht, Utrecht, The Netherlands
    Cerebrovasc Dis 14:22-6. 2002
    ..leptomeningeal vessels have been considered secondary collaterals, which are recruited only if the primary collateral circulation via the circle of Willis is insufficient...
  16. ncbi Influence of diabetes mellitus on coronary collateral flow: an answer to an old controversy
    R Zbinden
    Department of Cardiology, University Hospital Bern, Bern, Switzerland
    Heart 91:1289-93. 2005
    ..15). CONCLUSION: Quantitatively measured coronary CFI did not differ between diabetic and non-diabetic patients with stable coronary artery disease...
  17. ncbi Coronary collaterals improve prognosis in patients with ischemic heart disease
    Jakub J Regieli
    Department of Cardiology, University Medical Center Utrecht, The Netherlands
    Int J Cardiol 132:257-62. 2009
    ..We examined the effects of coronary collateral circulation on cardiovascular outcomes, with an emphasis on clinical prognostic value and on a putative role of IHD ..
  18. ncbi Reduced pericardial levels of endostatin correlate with collateral development in patients with ischemic heart disease
    Vipul R Panchal
    Department of Medicine, Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, 46202, USA
    J Am Coll Cardiol 43:1383-7. 2004
    ..growth factor, VEGF) or an anti-angiogenic factor (endostatin) related to the presence of coronary collateral circulation in patients with significant coronary artery disease (CAD)...
  19. ncbi Extrahepatic collateral supply of hepatocellular carcinoma by the intercostal arteries
    Sung Il Park
    Department of Diagnostic Radiology, Soonchunhyang University Chonan Hospital, Chonan, South Korea
    J Vasc Interv Radiol 14:461-8. 2003
    ..CONCLUSION: ICA collateral supply of HCC usually occurs in advanced HCC or after multiple sessions of TACE. When there are suggestive CT findings, ICA collaterals should be sought when TACE is performed in the management of HCC...
  20. ncbi Relation of various plasma growth factor levels in patients with stable angina pectoris and total occlusion of a coronary artery to the degree of coronary collaterals
    Carlo Briguori
    Laboratory of Interventional Cardiology and Department of Cardiology, Clinica Mediterranea, Naples, Italy
    Am J Cardiol 97:472-6. 2006
    ..In conclusion, plasma levels of angiogenic growth factors differ among patients with stable angina pectoris and longstanding total coronary occlusion...
  21. ncbi Determinants and prognostic significance of collaterals in patients undergoing coronary revascularization
    Hendrik M Nathoe
    Department of Cardiology, Heart Lung Center Utrecht, Utrecht
    Am J Cardiol 98:31-5. 2006
    ..Variables that reflect the duration and severity of the atherosclerotic and ischemic burden determine their presence...
  22. ncbi Territorial arterial spin labeling in the assessment of collateral circulation: comparison with digital subtraction angiography
    Soke Miang Chng
    Department of Neuroradiology, National Neuroscience Institute, Singapore
    Stroke 39:3248-54. 2008
    b>Collateral circulation plays a vital role in patients with steno-occlusive disease, in particular for predicting stroke outcome...
  23. ncbi Cross-sectional pattern of collateral vessels in patients with superficial femoral artery occlusion
    M B Wecksell
    Department of Radiology, Weill Medical College of Cornell University, New York, NY, USA
    Invest Radiol 36:422-9. 2001
    ..CONCLUSIONS: The majority of collateral vessels in the thigh are located in the fat or muscle within the posterior compartment near the femur at the level of the adductor canal...
  24. ncbi Differential effects of MCP-1 and leptin on collateral flow and arteriogenesis
    Stephan H Schirmer
    Research Group for Experimental and Clinical Arteriogenesis, Department of Internal Medicine III Cardiology and Angiology, University Hospital Freiburg, Breisacher Strasse 66 ZKF, D 79106 Freiburg, Germany
    Cardiovasc Res 64:356-64. 2004
    ....
  25. ncbi The human coronary collateral circulation
    Christian Seiler
    Cardiology, University Hospital, Bern, Switzerland
    Eur J Clin Invest 40:465-76. 2010
    ..Well-developed coronary collateral arteries in patients with coronary artery disease (CAD) mitigate myocardial infarcts and improve survival...
  26. ncbi Growth factors in the collateral circulation of chronic total coronary occlusions: relation to duration of occlusion and collateral function
    Gerald S Werner
    Clinic for Internal Medicine I, Friedrich Schiller University Jena, Jena, Germany
    Circulation 110:1940-5. 2004
    ..Despite extensive animal experimental evidence, there are few data on the relation of growth factors and collateral function in humans...
  27. ncbi Pharmacodynamics of basic fibroblast growth factor: route of administration determines myocardial and systemic distribution
    D F Lazarous
    Experimental Physiology and Pharmacology Section, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Cardiovasc Res 36:78-85. 1997
    ..This study evaluated differential regional uptake of 125I labeled bFGF following bolus intravenous, Swan Ganz, left atrial, intracoronary, and pericardial delivery...
  28. ncbi Effect of coronary collaterals on long-term prognosis in patients undergoing primary angioplasty for acute ST-elevation myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am J Cardiol 106:605-11. 2010
    ..In conclusion, the presence of a well-developed collateral network before mechanical reperfusion in patients with STEMI is associated with improved long-term survival and lower major adverse cardiovascular event rates...
  29. ncbi Role of coronary collaterals in off-pump and on-pump coronary bypass surgery
    Hendrik M Nathoe
    Department of Cardiology, Heart Lung Center Utrecht, Utrecht, The Netherlands
    Circulation 110:1738-42. 2004
    ..CONCLUSIONS: Collaterals protect against perioperative myocardial infarction during off-pump surgery but not during on-pump surgery and are associated with a better 1-year event-free survival...
  30. ncbi Leg ischemia: assessment with MR angiography and spectroscopy
    Iris Baumgartner
    Swiss Cardiovascular Center, Division of Angiology and Departments of Diagnostic, Interventional, and Pediatric Radiology, University Hospital Bern, Freiburgstrasse 10, 3010 Bern, Switzerland
    Radiology 234:833-41. 2005
    ..03; distal calf, P=.005). CONCLUSION: MR angiography and MR spectroscopy of deoxymyoglobin can help document changes in visualization of collateral vessels and tissue perfusion in patients with CLI...
  31. ncbi Stimulation of collateral artery growth: travelling further down the road to clinical application
    S H Schirmer
    Department of Cardiology, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Heart 95:191-7. 2009
    ..Future directions in the translation from bench to bedside and potential new approaches to the stimulation of vascular growth are discussed...
  32. ncbi Comparison of the cardioprotective effect of prodromal angina pectoris and collateral circulation in patients with a first anterior wall acute myocardial infarction
    Masaharu Ishihara
    Department of Cardiology, Hiroshima City Hospital, Hiroshima, Japan
    Am J Cardiol 95:622-5. 2005
    To compare the cardioprotective effect of prodromal angina pectoris and collateral circulation, 245 patients with first anterior acute myocardial infarction who underwent coronary angioplasty within 12 hours of symptoms were studied...
  33. ncbi Role of collateral circulation in the acute phase of ST-segment-elevation myocardial infarction treated with primary coronary intervention
    P Elsman
    Department of Cardiology, Isala Klinieken, locatie Weezenlanden, Groot Wezenland 20, 8011 JW Zwolle, The Netherlands
    Eur Heart J 25:854-8. 2004
    ....
  34. ncbi [A case of repeated intracerebral hemorrhage due to a ruptured aneurysm of collateral circulation from the posterior cerebral artery to the middle cerebral artery]
    Ayumi Narisawa
    Department of Neurosurgery, Saitama Red Cross Hospital, Japan
    No Shinkei Geka 37:787-92. 2009
    ..Even if intraparenchymal hematoma presents without SAH, and even if it is located at a rare site for aneurysms, we should inspect the source of bleeding considering factors preventing SAH arising from aneurysms...
  35. ncbi Magnetic resonance angiography of collateral blood supply to spinal cord in thoracic and thoracoabdominal aortic aneurysm patients
    Walter H Backes
    Department of Radiology, Maastricht University Hospital, Maastricht, The Netherlands
    J Vasc Surg 48:261-71. 2008
    ....
  36. ncbi Importance of collateral circulation in coronary heart disease
    Colin Berry
    Department of Medicine, Institut de Cardiologie de Montreal, Montreal, Quebec, Canada
    Eur Heart J 28:278-91. 2007
    ..We endeavoured to review the methods for coronary artery collateral assessment, the predictors and clinical importance of collateral blood flow, and the potential for therapeutic augmentation of collateral anastomoses...
  37. ncbi Effect of glucometabolic disorders on the formation of coronary collaterals in occlusive coronary artery disease
    Zekeriya Nurkalem
    Siyami Ersek Thoracic and Cardiovascular Surgery Center, Cardiology Department, Istanbul, Turkey
    Acta Cardiol 63:141-6. 2008
    ..The primary aim of this study was to assess the effect of glucometabolic disorders on coronary collateral vessels in patients with occlusive coronary artery disease...
  38. ncbi Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2
    Renhai Cao
    Laboratory of Angiogenesis Research, Microbiology and Tumor Biology Center, Karolinska Institutet, Stockholm, Sweden
    Nat Med 9:604-13. 2003
    ..Our data show that a specific combination of angiogenic factors establishes functional and stable vascular networks, and provides guidance for the ongoing clinical trials of angiogenic factors for the treatment of ischemic diseases...
  39. ncbi Collateral artery growth (arteriogenesis) after experimental arterial occlusion is impaired in mice lacking CC-chemokine receptor-2
    Matthias Heil
    Department of Experimental Cardiology, Max Planck Institute for Physiological and Clinical Research, Bad Nauheim, Germany
    Circ Res 94:671-7. 2004
    ..In conclusion, our results demonstrate that the CCR2 signaling pathway is essential for efficient collateral artery growth...
  40. ncbi Risk factors for poor collateral development in claudication
    Salvatore De Vivo
    Department of Vascular Surgery, Karolinska Hospital, Stockholm, Sweden
    Vasc Endovascular Surg 39:519-24. 2005
    ..In patients with claudication and SFA occlusion, few collaterals from the deep femoral artery appear to be associated with having diabetes and a short duration of symptoms...
  41. ncbi Beta-blockers, myocardial ischaemia and collateral circulation
    M Sato
    Eur Heart J 25:537-9. 2004
  42. ncbi Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice
    Radia Tamarat
    , , Institut Federatif de Recherche Circulation-Paris 7, , 75475 Paris Cedex 10, France
    Proc Natl Acad Sci U S A 100:8555-60. 2003
    ..This effect is probably mediated by restoration of matrix degradation processes that are disturbed as a result of AGE accumulation...
  43. ncbi The human coronary collateral circulation
    Christian Seiler
    Heart 89:1352-7. 2003
  44. ncbi Elevated fluid shear stress enhances postocclusive collateral artery growth and gene expression in the pig hind limb
    Frederic Pipp
    Max-Planck-Institute for Physiological and Clinical Research, Bad Nauheim, D-61231 Germany
    Arterioscler Thromb Vasc Biol 24:1664-8. 2004
    ..The role of fluid shear stress on the development of a collateral circulation was studied by abruptly increasing collateral blood flow by a distal femoral artery-to-vein anastomosis...
  45. ncbi Low-level laser therapy accelerates collateral circulation and enhances microcirculation
    F R Mohammed Ihsan
    Department of Anatomy, Al-Kindy College of Medicine, University of Baghdad, Iraq
    Photomed Laser Surg 23:289-94. 2005
    OBJECTIVE: To evaluate the efficacy of low-level laser therapy (LLLT) on collateral circulation and microcirculation if a blood vessel is occluded...
  46. ncbi High blood pressure is inversely related with the presence and extent of coronary collaterals
    J Koerselman
    1Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    J Hum Hypertens 19:809-17. 2005
    ..There is an inverse relationship between BP and the presence and extent of CC circulation in patients with ischaemic heart disease...
  47. ncbi Portosystemic shunts in a large cohort of patients with liver cirrhosis: detection rate and clinical relevance
    Enrico Maria Zardi
    Department of Clinical Medicine, Campus Bio Medico University, Via Alvaro del Portillo, Rome, 200 00128, Italy
    J Gastroenterol 44:76-83. 2009
    ..This study aimed to determine the detection rate and clinical relevance of portosystemic collaterals...
  48. ncbi The relationship of chronic angiotensin converting enzyme inhibitor use and coronary collateral vessel development
    Timucin Altin
    Department of Cardiology, Ankara University School of Medicine, Ankara, Turkey
    Int Heart J 48:435-42. 2007
    ..We hypothesized that the blockage of angiotensin II production by ACE inhibitors might interfere with collateral development in patients with coronary occlusion...
  49. ncbi [Dissecting aneurysm of the anterior cerebral artery with later development of collateral circulation: a case report]
    K Nakanishi
    Department of Neurosurgery, Kinki University School of Medicine, 377-2, Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan
    No Shinkei Geka 29:781-5. 2001
    ..Its etiology remains uncertain, and its natural course is unclear. Surgical intervention is recommended for patients with intracranial hemorrhage, while non surgical therapies have achieved good outcomes in ischemic cases...
  50. ncbi Impaired acute collateral recruitment as a possible mechanism for increased cardiac adverse events in patients with diabetes mellitus
    Gerald S Werner
    Clinic for Internal Medicine III, Friedrich Schiller University, Jena, Germany
    Eur Heart J 24:1134-42. 2003
    ..An impaired collateral function is considered a possible explanation. This study should assess the influence of diabetes on collaterals by direct invasive assessment of collateral function...
  51. ncbi Vascular endothelial growth factor-A-induced chemotaxis of monocytes is attenuated in patients with diabetes mellitus: A potential predictor for the individual capacity to develop collaterals
    J Waltenberger
    Department of Internal Medicine II, Ulm University Medical Center, Ulm, Germany
    Circulation 102:185-90. 2000
    ..Thus far, it has not been possible to identify differences in individual responses to VEGF-A stimulation because of the lack of an ex vivo assay...
  52. ncbi Exogenous application of transforming growth factor beta 1 stimulates arteriogenesis in the peripheral circulation
    Niels van Royen
    Max Planck Institute for Physiological and Clinical Research, Department of Experimental Cardiology, Bad Nauheim, Germany
    FASEB J 16:432-4. 2002
    ..led to an increase in both the number of visible collateral arteries as well as the conductance of the collateral circulation (4.0 +/- 0.5 ml/min/100 mmHg vs. 28.9 +/- 3.7 ml/min/100 mmHg, P<0.05)...
  53. ncbi Time course of arteriogenesis following femoral artery occlusion in the rabbit
    I E Hoefer
    Department of Experimental Cardiology, Max Planck Institute for Physiological and Clinical Research, Benekestr 2, D 61231, Bad Nauheim, Germany
    Cardiovasc Res 49:609-17. 2001
    ..We examined the time course of arteriogenesis (collateral artery growth) after femoral artery ligation and the effect of monocyte chemoattractant protein-1 (MCP-1)...
  54. ncbi Ultrastructure and molecular histology of rabbit hind-limb collateral artery growth (arteriogenesis)
    D Scholz
    Department of Experimental Cardiology, Max Planck Institute, Bad Nauheim, Germany
    Virchows Arch 436:257-70. 2000
    ..We conclude that the process of arteriogenesis, which leads to the positive remodeling of an arteriole into an artery up to 12 times its original size, can be modified by modulators of inflammation...
  55. ncbi Absence of myocardial ischemia during sudden controlled occlusion of coronary arteries in patients with well-developed collateral vessels
    K Miwa
    Second Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Japan
    Coron Artery Dis 10:459-63. 1999
    ....
  56. ncbi MR regional perfusion imaging: visualizing functional collateral circulation
    C C T Lim
    Department of Neuroradiology, National Neuroscience Institute, Singapore
    AJNR Am J Neuroradiol 28:447-8. 2007
    ..RPI may be useful to study functional collateral circulation and hence guide therapy in ischemic disease.
  57. ncbi Coronary collateralization: determinants of adequate distal vessel filling after arterial occlusion
    Jens G Kilian
    Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Coron Artery Dis 13:155-9. 2002
    ..b>Collateral circulation to the occluded artery was graded as 'poor' (no or incomplete filling) or 'rich' (complete filling)...
  58. ncbi [Development of pre-hepatic portal hypertension of the rat]
    M A Aller Reyero
    Facultad de Medicina, Universidad Complutense, Pza Ramón y Cajal s n, 28040 Madrid
    An Med Interna 19:341-51. 2002
    ..A long-term study of the prehepatic portal hypertension model by triple stenosing ligation of the portal vein in the rat...
  59. ncbi Therapeutic angiogenesis in peripheral arterial disease: can biotechnology produce an effective collateral circulation?
    D J Collinson
    Centre for Integrated Systems Biology and Medicine, School of Medical and Surgical Sciences University of Nottingham, Nottingham, UK
    Eur J Vasc Endovasc Surg 28:9-23. 2004
    ....
  60. ncbi Coronary collateral quantitation in patients with coronary artery disease using intravascular flow velocity or pressure measurements
    C Seiler
    Department of Cardiology, University Hospital, Bern, Switzerland
    J Am Coll Cardiol 32:1272-9. 1998
    ..This study evaluated two methods for the quantitative measurement of collaterals using intracoronary (IC) blood flow velocity or pressure measurements...
  61. ncbi Monocyte chemotactic protein-1 increases collateral and peripheral conductance after femoral artery occlusion
    W D Ito
    Department of Experimental Cardiology, Max Planck Institute for Physiological and Clinical Research, Bad Nauheim, Germany
    Circ Res 80:829-37. 1997
    ..01; peripheral conductance, 119.3 +/- 22.37 versus 45.4 +/- 6.80 mL/min per 100 mm Hg; P < .05). These results suggest that activation of monocytes plays an important role in collateral growth as well as in capillary sprouting...
  62. ncbi Elevated levels of C-reactive protein are associated with impaired coronary collateral development
    S Gulec
    Department of Cardiology, School of Medicine, Ankara University, Ankara, Turkey
    Eur J Clin Invest 36:369-75. 2006
    ..The aim of this study was to investigate the association between high sensitivity CRP (hsCRP) levels and the extent of coronary collaterals...
  63. ncbi Physiologically assessed coronary collateral flow and adverse cardiac ischemic events: a follow-up study in 403 patients with coronary artery disease
    Michael Billinger
    Division of Cardiology, Swiss Cardiovascular Center Bern, CH-3010 Bern, Switzerland
    J Am Coll Cardiol 40:1545-50. 2002
    ....
  64. ncbi Blocking thrombospondin-1/CD47 signaling alleviates deleterious effects of aging on tissue responses to ischemia
    Jeff S Isenberg
    MPH, Laboratory of Pathology, Building 10, 2A33, National Cancer Institute, Bethesda, Maryland 20892 1500, USA
    Arterioscler Thromb Vasc Biol 27:2582-8. 2007
    ..In this study we investigate the role TSP1 plays in regulating blood flow in the presence of advanced age and atherosclerotic vascular disease...
  65. ncbi [Arteriogenesis: a new strategy of therapeutic intervention in chronic arterial disorders. Cellular mechanism and experimental models]
    Franciska Erdo
    IVAX Gyógyszerkutató Intézet Kft, Farmakológia Osztály, Budapest
    Orv Hetil 148:633-42. 2007
    ....
  66. ncbi Congenital absence of the right pulmonary artery with coronary collaterals supplying the affected lung: effect on coronary perfusion
    Hasan Kadi
    Department of Cardiology, Gebze State Hospital, Istanbul, Turkey
    Cardiology 108:314-6. 2007
    ..In conclusion, clinicians should be aware of the possibility of undiagnosed cases of unilateral pulmonary artery agenesis presenting with chest pain in advanced age...
  67. ncbi Coronary ectasia with slow flow related to apical hypertrophic cardiomyopathy--a case report
    Masao Saotome
    Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, Hamamatsu, Japan
    Angiology 56:103-6. 2005
    ..This is the first case report that a mild apical hypertrophy induced severe CE with slow coronary flow. The authors recommend a long-term prophylaxis of thrombotic complications with antiplatelet agents in patients with CE...
  68. ncbi Aneurysm of the Vieussens' arterial ring
    Vishal Gupta
    Department of Interventional Cardiology, Division of Cardiology, Massachusetts General Hospital, Harvard School of Medicine, Boston, Massachusetts, USA
    J Invasive Cardiol 19:282-3. 2007
  69. ncbi Synchrotron radiation coronary microangiography for morphometric and physiological evaluation of myocardial neovascularization induced by endothelial progenitor cell transplantation
    Hiroto Iwasaki
    Stem Cell Translational Research, Kobe Institute of Biomedical Research and Innovation RIKEN Center for Developmental Biology, 2 2 Minatojima Minamimachi, Chuo Ku, Kobe 650 0047, Japan
    Arterioscler Thromb Vasc Biol 27:1326-33. 2007
    ..However, it has been technically difficult to obtain imaging evidence of collateral formation by conventional angiography...
  70. ncbi Pressure and flow across severe stenoses: does the intra-aortic balloon pump do its job?
    Morton J Kern
    Am Heart J 154:615-6. 2007
  71. ncbi Transthoracic echocardiographic visualization of a right coronary to left anterior descending artery collateral
    Albert Yuh-Jer Shen
    Department of Cardiology and the Center for Medical Education, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California 90027, USA
    Echocardiography 23:162-3. 2006
  72. ncbi Optimal reactive oxygen species concentration and p38 MAP kinase are required for coronary collateral growth
    Petra Rocic
    Department of Physiology, Louisiana State Univeristy Health Sciences Center, New Orleans, Louisiana, USA
    Am J Physiol Heart Circ Physiol 292:H2729-36. 2007
    ..p38 MAP kinase inhibition prevented HCAEC tube formation and partially blocked RI-induced CCG (42 +/- 7% of normal zone flow), indicating that p38 MAP kinase is a critical signaling mediator of CCG...
  73. ncbi Significant correlation of recruitable coronary collateral blood flow determined by coronary wedge pressure with ST-segment elevation during coronary occlusion
    Shigeshi Kamikawa
    Department of Medicine and Medical Science, Okayama University Graduates School of Medicine and Dentistry, Japan
    Coron Artery Dis 16:231-6. 2005
    ..Repeat transient coronary occlusion during PCI did not lead to increased collateral blood flow...
  74. ncbi The effect of electrical neurostimulation on collateral perfusion during acute coronary occlusion
    Jessica de Vries
    Dept of Cardiology, Thoraxcenter, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    BMC Cardiovasc Disord 7:18. 2007
    ..We sought to study the effect of electrical neurostimulation on collateral perfusion...
  75. ncbi Anomalous origin of the left coronary artery from the pulmonary artery in an elderly patient, football player in youth
    Antonio Facciorusso
    Department of Cardiology, IRCCS Casa Sollievo, della Sofferenza, San Giovanni Rotondo FG, Italy
    J Cardiovasc Med (Hagerstown) 9:1066-9. 2008
    ..However, the exact reason why these favourable evolutions (both vascular and clinical) occur only in some individuals remains largely unknown...
  76. ncbi Branching of main trunk of left coronary artery and importance of her diagonal branch in cases of coronary insufficiency
    Almira Lujinovic
    Institute of Anatomy, Faculty of Medicine, University of Sarajevo, Cekalusa 90, 71000 Sarajevo, Bosnia and Herzegovina
    Bosn J Basic Med Sci 5:69-73. 2005
    ..This branch, including its anastomoses, presents important pattern of the collateral blood flow, which has special meaning, under conditions of coronary insufficiency...
  77. ncbi Percutaneous coronary intervention and the no-reflow phenomenon
    William J van Gaal
    Department of Cardiology, Level 2, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Expert Rev Cardiovasc Ther 5:715-31. 2007
    ..Compared with patients in whom no-reflow is transient, refractory no-reflow is associated with a markedly increased risk of 30-day mortality...
  78. ncbi Angiopoietin-2 stimulates blood flow recovery after femoral artery occlusion by inducing inflammation and arteriogenesis
    Sarah L Tressel
    Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Emory University, Atlanta, GA 30322, USA
    Arterioscler Thromb Vasc Biol 28:1989-95. 2008
    ..We hypothesized that Ang2 plays an important role in blood flow recovery after arterial occlusion in vivo by regulating angiogenesis and arteriogenesis...
  79. ncbi Use and limitations of magnetic resonance phase-contrast assessment of coronary flow reserve in a model of collateral dependence
    Jamil A Malik
    BrookeArmy Medical Center, Fort Sam Houston, Texas 78234, USA
    Comp Med 55:317-25. 2005
    ..It also demonstrates the disparity between epicardial and myocardial measures of coronary flow reserve with collateral dependence and the caveats for PC-MRI use in models of progressive coronary constriction...
  80. ncbi [Objective methods of assessment of coronary angiogenesis]
    A E Semenova
    Kardiologiia 48:19-23. 2008
    ....
  81. ncbi A potential evidence to explain the reason behind the devastating prognosis of coronary artery disease in uraemic patients: renal insufficiency is associated with poor coronary collateral vessel development
    Murat Sezer
    Istanbul University, Istanbul Faculty of Medicine, Department of Cardiology, 34390, Capa Istanbul, Turkey
    Int J Cardiol 115:366-72. 2007
    The potential of individuals to develop coronary collateral circulation is often neglected but is of potential major importance in myocardial vulnerability...
  82. ncbi [Correlation between pressure-derived coronary collateral flow and Rentrop grade after primary percutaneous intervention of acute myocardial infarction]
    Zhi xiong Cai
    Affiliated Shantou Hospital of Sun Yat sen University, Shantou 515031, China
    Nan Fang Yi Ke Da Xue Xue Bao 26:799-801. 2006
    ..To analyze the correlation between pressure-derived collateral coronary flow (PDCF) and Rentrop grade of patients with acute myocardial infarction (AMI)...
  83. ncbi Functional assessment of the collateral-dependent circulation in chronic total coronary occlusion using transthoracic Doppler ultrasound and venous adenosine infusion
    Francesco Pizzuto
    Department of Cardiology, Tor Vergata University, Rome, Italy
    Am J Cardiol 98:197-203. 2006
    ..patients with chronic total coronary occlusion had collateral flow withdrawal at stress, which occurs when collateral circulation is poor and when the donor artery is stenotic...
  84. ncbi Cut-off value of coronary flow velocity reserve by transthoracic Doppler echocardiography for the assessment of significant donor left anterior descending artery stenosis in patients with spontaneously visible collaterals
    Shinichi Iwata
    The Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    Am J Cardiol 98:298-302. 2006
    We evaluated the influence of collateral circulation on a donor left anterior descending artery and an appropriate cut-off value of coronary flow velocity reserve for the diagnosis of significant donor left anterior descending artery ..
  85. ncbi Impaired coronary collateral vessel development in patients with metabolic syndrome
    Hasan Turhan
    Department of Cardiology, Inonu University, Malatya and Department of Cardiology, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey
    Coron Artery Dis 16:281-5. 2005
    ..and evidence of myocardial ischemia suggest that some other factors may affect the development of collateral circulation. In the present study we aimed to evaluate coronary collateral circulation in patients with metabolic ..
  86. ncbi the coronary venous system: an alternative route of access to the myocardium
    Ajay K Jain
    Department of Cardiology, London Chest Hospital, London, United Kingdom
    J Invasive Cardiol 18:563-8. 2006
    ..Finally, the use of the coronary venous system by the cardiac electrophysiologist is reviewed...
  87. ncbi Transesophageal Doppler echocardiographic detection of intramyocardial collateral flow to the right coronary artery and changes in the flow to the inferior left ventricular wall immediately after coronary artery bypass grafting
    Jianwen Wang
    Department of Anesthesia, University Hospital of Basel, Basel, Switzerland
    Am J Cardiol 98:1587-92. 2006
    ..In conclusion, these findings indicate that Doppler TEE may detect collateral flow in the inferior left ventricular wall, and that there are typical changes in collateral and physiologic flow after CABG...
  88. ncbi Kugel's artery: an anatomical and angiographic study using a new technique
    Christos E Nerantzis
    Forensic Medical Services of Athens, Greece
    Tex Heart Inst J 31:267-70. 2004
    ..Kugel's artery provides an additional direct arterial anastomosis in the same area in 6% of the hearts...
  89. ncbi Coronary collateral flow in response to endurance exercise training
    Rainer Zbinden
    Department of Cardiology, University Hospital, Bern, Switzerland
    Eur J Cardiovasc Prev Rehabil 14:250-7. 2007
    ....
  90. ncbi New look at an old ring
    Larry A Latson
    Cleveland Clinic, Center for Pediatric and Congenital Heart Diseases, Cleveland, Ohio 44195, USA
    Catheter Cardiovasc Interv 71:572. 2008
  91. ncbi Direct assessment of coronary steal and associated changes of collateral hemodynamics in chronic total coronary occlusions
    Gerald S Werner
    Clinic for Internal Medicine III, Friedrich Schiller University, Jena, Germany
    Circulation 106:435-40. 2002
    ..Coronary steal can occur in collateral-dependent myocardium during pharmacologically induced vasodilation. This study assessed coronary steal invasively in chronic total coronary occlusions (TCOs)...
  92. ncbi Myocardial viability, coronary flow reserve, and in-hospital predictors of late recovery of contractility following successful primary stenting for acute myocardial infarction
    F Beygui
    Adult Cardiology Department, Necker University Hospital, 149, rue de Sevres, 75015, Paris, France
    Heart 89:179-83. 2003
    ..To assess the relation between myocardial viability, coronary flow reserve, and recovery of myocardial contractility after stenting for acute myocardial infarction...
  93. ncbi Acquired coropulmonary and bronchopulmonary anastomoses occurring in association with pulmonary arterial occlusion and veno-occlusive disease generating potential coronary steal
    Robert J MacFadyen
    Cardiac Unit, Raigmore Hospital, Inverness, UK
    Int J Cardiovasc Intervent 5:40-3. 2003
    The development of collateral circulation is a general vascular response which is well characterised in the heart. The most common precipitant of this is ischaemia and the most common manifestation is intra coronary collateralisation...
  94. ncbi Differential response of coronary collateral channels to atrial pacing and balloon occlusion at angioplasty
    Mark J Mason
    Department of Cardiology, Harefield Hospital, Royal Brompton and Harefield NHS Trust, Harefield, Middlesex, UB9 6JH, UK
    Coron Artery Dis 14:81-7. 2003
    ..Ischaemic symptoms are attenuated with repetitive pacing independent of collateral flow, suggesting an additional preconditioning response...
  95. ncbi Is there functional collateral flow during vascular occlusion in angiographically normal coronary arteries?
    Kerstin Wustmann
    Department of Cardiology, Swiss Cardiovascular Center Bern, University Hospital, Bern, Switzerland
    Circulation 107:2213-20. 2003
    ..Such preformed coronary collateral vessels could form the basis for subsequently developing protective natural bypasses in the presence of coronary artery disease...
  96. ncbi Endogenous myocardial angiogenesis and revascularization using a gastric submucosal patch
    Marc A Ruel
    Center for Minimally Invasive Surgery, Harvard Medical School, Boston, Massachusetts, USA
    Ann Thorac Surg 75:1443-9. 2003
    ..CONCLUSIONS: This model results in an angiogenic process of significantly greater magnitude than that resulting from chronic myocardial ischemia alone, without the need for exogenous angiogenic agents...
  97. ncbi Promotion of collateral growth by granulocyte-macrophage colony-stimulating factor in patients with coronary artery disease
    Gerald S Werner
    Circulation 105:e175; author reply e175. 2002
  98. ncbi Can thrombolytic therapy provide beneficial effects additional to epicardial coronary artery recanalization? A study based on coronary pressure measurement
    Murat Sezer
    Department of Cardiology, Istanbul School of Medicine, Istanbul University, Capa, Turkey
    Coron Artery Dis 13:125-30. 2002
    ....
  99. ncbi Through the back door - retrograde stenting in chronic total occlusions
    Christoph Hehrlein
    Catheter Cardiovasc Interv 72:370. 2008
  100. ncbi Collateral channels from the superior caval vein to the cardiac veins after atrial repair for transposition
    Gabriella Agnoletti
    , , Paris, France
    Cardiol Young 18:353-4. 2008
  101. ncbi Assessment of ischemia-induced microvascular remodeling using contrast-enhanced ultrasound vascular anatomic mapping
    Marco Pascotto
    Cardiovascular Division, University of Virginia, Charlottesville, Virginia, USA
    J Am Soc Echocardiogr 20:1100-8. 2007
    ..We conclude that CEU can separately assess collateral development, more distal arteriogenesis, and secondary changes in capillary perfusion that occur differentially with ischemia and growth factor therapy...

Research Grants70

  1. Quantifying Collateral Perfusion in Cerebrovascular Disease
    GREGORY ZAHARCHUK; Fiscal Year: 2009
    ..population for this study, as they tend to be young and otherwise healthy, but typically have extensive collateral circulation. We also aim to demonstrate that ASL CBF measurements sensitive to slow flow, such as long post-label ..
  2. Quantifying Collateral Perfusion in Cerebrovascular Disease
    GREGORY GEORGE ZAHARCHUK; Fiscal Year: 2010
    ..population for this study, as they tend to be young and otherwise healthy, but typically have extensive collateral circulation. We also aim to demonstrate that ASL CBF measurements sensitive to slow flow, such as long post-label ..
  3. Reactive Oxygen Species in Coronary Collateral Growth
    WILLIAM CHILIAN; Fiscal Year: 2009
    ..the cell type or types in the heart responsible for redox signaling in the growth of the coronary collateral circulation in response to repetitive ischemia...
  4. Reactive Oxygen Species in Coronary Collateral Growth
    William M Chilian; Fiscal Year: 2010
    ..the cell type or types in the heart responsible for redox signaling in the growth of the coronary collateral circulation in response to repetitive ischemia...
  5. EFFECT OF DRUGS UPON MYOCARDIAL HYPOXIA
    Garrett Gross; Fiscal Year: 1993
    ..collateral blood flow, a second major objective will be to determine the effects of KCOs on the coronary collateral circulation in dogs with different degrees of collateral development...
  6. PEROXYLIPIDS/NITRIC OXIDE IN THROMBOTIC STROKE
    Brant Watson; Fiscal Year: 1993
    ..Observation of infarct mitigation by EDRF stimulation would suggest that EDRF-induced activation of collateral circulation be used clinically to reduce infarct volume, even if the MCA (or other intracranial artery) remains ..
  7. Stem cell-based therapy in heart failure: aging effects
    Mohamed Gaballa; Fiscal Year: 2003
    Induction of collateral circulation after myocardial infarction (MI) is impaired in aging. However, the mechanisms of this impairment are unclear...
  8. Exercise, Antioxidants, and I-R Injury
    Scott Powers; Fiscal Year: 2006
    ..Potential mechanisms to explain the protective effect of exercise include improved collateral circulation, elevation of cardiac heat shock proteins, and increased myocardial antioxidant capacity...
  9. Collateral Circulation in Acute Ischemic Stroke
    David Liebeskind; Fiscal Year: 2007
    b>Collateral circulation is a fundamental component of stroke pathophysiology that has been relatively unexplored...
  10. HYPOXIA INDUCIBLE VEGF PRODUCTION IN SLEEP APNEA
    Andrew Levy; Fiscal Year: 2003
    Angiogenesis is the physiological adaptive response of a tissue to hypoxia. The coronary collateral circulation of the heart represents such an adaptive response and is an important determinant in the extent of tissue damage following ..
  11. Angiogenesis in Diseased Model
    Nilanjana Maulik; Fiscal Year: 2010
    ..Abnormalities of the coronary collateral circulation have been reported in clinical and experimental diabetes mellitus...
  12. NOVEL ANGIOGENESIS INHIBITOR FROM CARTILAGE
    Marsha Moses; Fiscal Year: 2002
    ..these latter cases, the ability to induce neovascularization, revascularize damaged tissue and develop the collateral circulation would be desirable...
  13. MRI OF COLLATERAL DEVELOPMENT IN THE HEART
    Michael Jerosch Herold; Fiscal Year: 2001
    DESCRIPTION (Adapted from Applicants Abstract): In ischemic heart disease the presence and extent of collateral circulation can prevent myocardial infarction, or at least limit the damage and reduce the size of infarcts...