plasma volume

Summary

Summary: Volume of PLASMA in the circulation. It is usually measured by INDICATOR DILUTION TECHNIQUES.

Top Publications

  1. ncbi Arterial remodeling and plasma volume expansion in caveolin-1-deficient mice
    Sebastian Albinsson
    Department of Experimental Medical Science, Lund University, SE 221 84 Lund, Sweden
    Am J Physiol Regul Integr Comp Physiol 293:R1222-31. 2007
  2. ncbi A novel hydroxyethyl starch (Voluven) for effective perioperative plasma volume substitution in cardiac surgery
    R C Gallandat Huet
    Department of Anesthesiology, University Hospital Groningen, The Netherlands
    Can J Anaesth 47:1207-15. 2000
  3. ncbi Voluven, a lower substituted novel hydroxyethyl starch (HES 130/0.4), causes fewer effects on coagulation in major orthopedic surgery than HES 200/0.5
    O Langeron
    , , Paris, France
    Anesth Analg 92:855-62. 2001
  4. pmc Atrial natriuretic peptide modulation of albumin clearance and contrast agent permeability in mouse skeletal muscle and skin: role in regulation of plasma volume
    Fitz Roy E Curry
    Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, Davis, CA 95616, USA
    J Physiol 588:325-39. 2010
  5. pmc Human circulatory and thermoregulatory adaptations with heat acclimation and exercise in a hot, dry environment
    B Nielsen
    August Krogh Institute, University of Copenhagen, Denmark
    J Physiol 460:467-85. 1993
  6. doi Chronic heart failure leads to an expanded plasma volume and pseudoanaemia, but does not lead to a reduction in the body's red cell volume
    Christopher Adlbrecht
    Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Eur Heart J 29:2343-50. 2008
  7. ncbi Renal function and plasma volume following ultramarathon cycling
    G Neumayr
    Institute of Sports Medicine, University Clinics of Innsbruck, Innsbruck, Austria
    Int J Sports Med 26:2-8. 2005
  8. ncbi Simultaneous determination of total body water and plasma volume in conscious dogs by the indicator dilution principle
    Søren Wamberg
    Department of Physiology and Pharmacology, University of Southern Denmark, Odense, Denmark
    J Nutr 132:1711S-3S. 2002
  9. pmc Atrap deficiency increases arterial blood pressure and plasma volume
    Mona Oppermann
    Children s Hospital, University Medical Center, Germany
    J Am Soc Nephrol 21:468-77. 2010
  10. pmc Relative plasma volume monitoring during hemodialysis AIDS the assessment of dry weight
    Arjun D Sinha
    Division of Nephrology, Indiana University School of Medicine, Indianapolis, Ind 46202, USA
    Hypertension 55:305-11. 2010

Detail Information

Publications222 found, 100 shown here

  1. ncbi Arterial remodeling and plasma volume expansion in caveolin-1-deficient mice
    Sebastian Albinsson
    Department of Experimental Medical Science, Lund University, SE 221 84 Lund, Sweden
    Am J Physiol Regul Integr Comp Physiol 293:R1222-31. 2007
    ..Tracer-dilution experiments showed increased plasma volume in KO...
  2. ncbi A novel hydroxyethyl starch (Voluven) for effective perioperative plasma volume substitution in cardiac surgery
    R C Gallandat Huet
    Department of Anesthesiology, University Hospital Groningen, The Netherlands
    Can J Anaesth 47:1207-15. 2000
    To compare the new hydroxyethyl starch HES 130/0.4 (Voluven) and the standard HES 200/0.5 (pentastarch) regarding effectiveness for plasma volume substitution and safety of large volumes in heart surgery.
  3. ncbi Voluven, a lower substituted novel hydroxyethyl starch (HES 130/0.4), causes fewer effects on coagulation in major orthopedic surgery than HES 200/0.5
    O Langeron
    , , Paris, France
    Anesth Analg 92:855-62. 2001
    Hydroxyethyl starch (HES) solutions are effective plasma volume expanders. Impairment of coagulation occurs with large HES volumes infused perioperatively...
  4. pmc Atrial natriuretic peptide modulation of albumin clearance and contrast agent permeability in mouse skeletal muscle and skin: role in regulation of plasma volume
    Fitz Roy E Curry
    Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, Davis, CA 95616, USA
    J Physiol 588:325-39. 2010
    ..clearance with ANP treatment accounts for at most 30% of whole body clearance required for ANP to regulate plasma volume. Skin microcirculation responded to ANP similarly...
  5. pmc Human circulatory and thermoregulatory adaptations with heat acclimation and exercise in a hot, dry environment
    B Nielsen
    August Krogh Institute, University of Copenhagen, Denmark
    J Physiol 460:467-85. 1993
    ..6 to 21.4 l min-1; this was possibly due to an increased plasma volume and stroke volume. 4...
  6. doi Chronic heart failure leads to an expanded plasma volume and pseudoanaemia, but does not lead to a reduction in the body's red cell volume
    Christopher Adlbrecht
    Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Eur Heart J 29:2343-50. 2008
    ..and kidney function) including red cell volume (RCV) (by a 51 Cr assay) as well as related markers and plasma volume. The influence of each factor on haemoglobin concentrations was determined in a multiple regression model...
  7. ncbi Renal function and plasma volume following ultramarathon cycling
    G Neumayr
    Institute of Sports Medicine, University Clinics of Innsbruck, Innsbruck, Austria
    Int J Sports Med 26:2-8. 2005
    ..Creatinine (CR), urea, haemoglobin (Hb), haematocrit (Hct) and plasma volume (PV) were investigated in 16 male ultramarathon cyclists during the 1st Race Across the Alps in 2001 (distance:..
  8. ncbi Simultaneous determination of total body water and plasma volume in conscious dogs by the indicator dilution principle
    Søren Wamberg
    Department of Physiology and Pharmacology, University of Southern Denmark, Odense, Denmark
    J Nutr 132:1711S-3S. 2002
  9. pmc Atrap deficiency increases arterial blood pressure and plasma volume
    Mona Oppermann
    Children s Hospital, University Medical Center, Germany
    J Am Soc Nephrol 21:468-77. 2010
    ..Dose-response relationships of arterial BP after acute AngII infusion were similar in both genotypes. Plasma volume was significantly higher and plasma renin concentration was markedly lower in Atrap-/- mice compared with wild-..
  10. pmc Relative plasma volume monitoring during hemodialysis AIDS the assessment of dry weight
    Arjun D Sinha
    Division of Nephrology, Indiana University School of Medicine, Indianapolis, Ind 46202, USA
    Hypertension 55:305-11. 2010
    ..The objective of this study was to evaluate and validate relative plasma volume (RPV) monitoring as a marker of dry weight...
  11. doi Hydroxyethyl starch 130/0.42/6:1 for perioperative plasma volume replacement in 1130 children: results of an European prospective multicenter observational postauthorization safety study (PASS)
    Robert Sumpelmann
    Medizinische Hochschule Hannover, Klinik für Anästhesiologie und Intensivmedizin, Hannover, Germany
    Paediatr Anaesth 22:371-8. 2012
    ..42/6:1 in normal saline (ns-HES) or a balanced electrolyte solution (bal-HES) in children undergoing surgery...
  12. pmc Plasma volume, albumin, and fluid status in peritoneal dialysis patients
    Biju John
    Department of Nephrology, University Hospital of North Staffordshire, Stoke on Trent, Staffordshire, United Kingdom
    Clin J Am Soc Nephrol 5:1463-70. 2010
    ..We hypothesized that patients with a plasma albumin below the median value would have measurable overhydration without a proportional increase in plasma volume (PV).
  13. ncbi Plasma volume expansion and transcapillary fluid exchange in skeletal muscle of albumin, dextran, gelatin, hydroxyethyl starch, and saline after trauma in the cat
    Johan Persson
    Department of Anesthesiology and Intensive Care, Lund University and Lund University Hospital, Sweden
    Crit Care Med 34:2456-62. 2006
    To compare 5% albumin, 6% dextran 70, 3.5% gelatin, 6% hydroxyethyl starch 130/0.4, and saline regarding their plasma volume expanding effect after a surgical skeletal muscle trauma and their simultaneous effects on transvascular fluid ..
  14. pmc Measurement of plasma volume using fluorescent silica-based nanoparticles
    Christoph Eisner
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Appl Physiol (1985) 112:681-7. 2012
    b>Plasma volume (PV) is an important determinant of cardiovascular function and organ perfusion, and it is the target of infusion and diuretic therapies in daily clinical practice...
  15. ncbi Plasma volume expansion of 5% albumin, 4% gelatin, 6% HES 130/0.4, and normal saline under increased microvascular permeability in the rat
    Maris Dubniks
    Department of Anesthesiology and Intensive Care, Lund University Hospital, 22185, Lund, Sweden
    Intensive Care Med 33:293-9. 2007
    ..4 with one another and with normal saline regarding their plasma expanding effects at increased permeability and to compare the results with those from a previous study at normal permeability...
  16. ncbi Technical and physiological background of plasma volume measurement with indocyanine green: a clarification of misunderstandings
    Matthias Jacob
    Klinik fur Anasthesiologie, Ludwig Maximilians Universitat Munchen, Nussbaumstr 20, D 80336 Munich, Germany
    J Appl Physiol (1985) 102:1235-42. 2007
    The indocyanine green (ICG) dilution technique (DT) is frequently used for plasma volume (PV) measurement. However, because of inadequate knowledge about the properties of this dye, lack of accuracy has been attributed to the method...
  17. ncbi Effects of measurement of plasma activity input on normalization of glomerular filtration rate to plasma volume in dogs
    Naruepon Kampa
    Department of Surgery, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, Thailand
    Vet Radiol Ultrasound 48:585-93. 2007
    ..GFR can be normalized to plasma volume by a renographic method that uses the Rutland-Patlak plot with plasma activity and kidney activity inputs...
  18. ncbi Direct and indirect methods for determining plasma volume during thermoneutral and cold-water immersion
    Christopher J Gordon
    Faculty of Health Science, Australian Catholic University, Sydney, Australia
    Eur J Appl Physiol 89:471-4. 2003
    b>Plasma volume (PV), determined indirectly from changes in haematocrit (Hct) and haemoglobin concentration ([Hb]), underestimates the absolute PV change (Evans blue dye) during thermoneutral immersion...
  19. pmc The relationship of plasma volume, sympathetic tone, and proinflammatory cytokines in young healthy nonpregnant women
    Ira M Bernstein
    Department of Obstetrics and Gynecology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    Reprod Sci 16:980-5. 2009
    Preeclampsia has been associated with elevated proinflammatory markers, increased sympathetic activity, and decreased plasma volume (PV). We hypothesized that these associations would be identified in women prior to a first pregnancy.
  20. doi Orthostatic hypercoagulability: a novel physiological mechanism to activate the coagulation system
    Muhannad Masoud
    J Recanati Autonomic Dysfunction Center and the Thrombosis and Hemostasis Unit, Medicine, Rambam Health Care Campus, and Bruce Rappaport Faculty of Medicine, Technion IIT, Haifa, Israel
    Hypertension 51:1545-51. 2008
    ..Thirty minutes of standing caused a decrease in plasma volume by 12.0+/-0.5% and an increase in plasma protein by 13.0+/-0.7%...
  21. doi Hormonal and plasma volume changes after presyncope
    Helmut Hinghofer-Szalkay
    Institute of Adaptive and Spaceflight Physiology, Graz, Austria
    Eur J Clin Invest 41:1180-5. 2011
    ..Aim of this study was to test the hypothesis that after presyncope, some blood hormone pools increase while others decrease...
  22. ncbi Detection of capillary protein leakage by indocyanine green and glucose dilutions in septic patients
    H Ishihara
    Department of Anesthesiology, University of Hirosaki School of Medicine, Hirosaki Shi, Japan
    Crit Care Med 28:620-6. 2000
    ..To determine whether indocyanine green (ICG) and glucose dilutions can detect generalized capillary protein leakage in septic patients without requiring repeated measurements...
  23. ncbi Endothelium-dependent vasodilatation in formerly preeclamptic women correlates inversely with body mass index and varies independently of plasma volume
    Tessa Lommerse
    Department of Obstetrics and Gynecology, University of Maastricht, Maatricht, The Netherlands
    Reprod Sci 14:765-70. 2007
    Endothelial dysfunction and a subnormal plasma volume predispose to preeclampsia...
  24. pmc Erythropoietin treatment elevates haemoglobin concentration by increasing red cell volume and depressing plasma volume
    Carsten Lundby
    Copenhagen Muscle Research Center, Rigshospitalet section 7652, 2100 Copenhagen, Denmark
    J Physiol 578:309-14. 2007
    Erythropoietin (Epo) has been suggested to affect plasma volume, and would thereby possess a mechanism apart from erythropoiesis to increase arterial oxygen content...
  25. ncbi Effects of naloxone on the haemodynamic and renal functional responses to plasma volume expansion in conscious rabbits
    A Shweta
    Department of Physiology, Monash University, Clayton, Victoria, Australia
    Pflugers Arch 439:150-7. 1999
    We tested whether the opioid antagonist naloxone affects responses to plasma volume expansion (PVE) in conscious rabbits. Under basal conditions, naloxone (6 mg x kg-(1) plus 0.3 mg x kg(-1) x min(-1) i.v...
  26. ncbi Postural pseudoanemia: posture-dependent change in hematocrit
    Giris Jacob
    Jacob Recanati Autonomic Dysfunction Center, Internal Medicine C, Rambam Medical Center, Haifa, Israel
    Mayo Clin Proc 80:611-4. 2005
    ..Lying and standing plasma volume (PV) and hematocrit (Hct) values were determined for each subject...
  27. ncbi Oral salt supplementation during ultradistance exercise
    Dale B Speedy
    Department of General Practice and Primary Care, University of Auckland, New Zealand
    Clin J Sport Med 12:279-84. 2002
    The objective of this study was to determine whether sodium supplementation 1) influences changes in body weight, serum sodium [Na], and plasma volume (PV), and 2) prevents hyponatremia in Ironman triathletes.
  28. ncbi Impact of protein and carbohydrate supplementation on plasma volume expansion and thermoregulatory adaptation by aerobic training in older men
    Kazunobu Okazaki
    Department of Sports Medical Sciences, Shinshu University Graduate School of Medicine, Matsumoto 390 8621, Japan
    J Appl Physiol (1985) 107:725-33. 2009
    ..CHO) supplementation immediately after exercise each day during aerobic training facilitated plasma volume (PV) expansion and thermoregulatory and cardiovascular adaptations in older men...
  29. ncbi Pregnant rats treated with a serotonin precursor have reduced fetal weight and lower plasma volume and kallikrein levels
    Sofia P Salas
    Department of Obstetrics and Gynecology, Center for Medical Research, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Hypertension 50:773-9. 2007
    ..In pregnant rats, 5-HTP lowered plasma volume (control: 22+/-1.1; 5-HTP: 17+/-0.7 mL; P<0...
  30. ncbi Plasma volume expansion in pregnancy: implications for biomarkers in population studies
    Jessica M Faupel-Badger
    Mammary Biology and Tumorigenesis Laboratory, Center for Cancer Research, National Cancer Institute, MSC 4254, 37 Convent Drive, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:1720-3. 2007
    ..measurement of the concentration of hormones and other biomarkers in pregnant subjects is influenced by plasma volume expansion (PVE)...
  31. ncbi Low plasma volume coincides with sympathetic hyperactivity and reduced baroreflex sensitivity in formerly preeclamptic patients
    Dorette A Courtar
    Department of Obstetrics and Gynecology, University Hospital Maastricht, Maastricht, The Netherlands
    J Soc Gynecol Investig 13:48-52. 2006
    Preeclampsia is associated with enhanced sympathetic activity as well as subnormal plasma volume. Meanwhile, in over 50% of these complicated pregnancies, the subnormal plasma volume has been found to persist for a prolonged period after ..
  32. ncbi Reliability of peak-lactate, heart rate, and plasma volume following the Wingate test
    Y Weinstein
    The Ribstein Center for Sports Medicine Sciences and Research, The Wingate Institute, Israel
    Med Sci Sports Exerc 30:1456-60. 1998
    ..Additionally, the test-retest reliability of the heart rate (HR) and plasma volume changes (deltaPV) response was also evaluated.
  33. ncbi The cardiovascular response to lower body negative pressure in humans depends on seal location
    N Goswami
    Institute of Physiology, Center for Physiological Medicine, Medical University of Graz, Graz, Austria graz at
    Physiol Res 58:311-8. 2009
    ..Plasma density and indocyanine green concentrations assessed plasma volume changes and hepatic perfusion...
  34. ncbi Resuscitation from septic shock with capillary leakage: hydroxyethyl starch (130 kd), but not Ringer's solution maintains plasma volume and systemic oxygenation
    Gernot Marx
    Department of Anaesthesia, University of Liverpool, Liverpool L69 3GA, United Kingdom
    Shock 21:336-41. 2004
    ..synthetic colloid hydroxyethyl starch (HES 130 kD) and a crystalloid regimen with Ringer's solution (RS) on plasma volume (PV) maintenance as well as on systemic and regional hemodynamics...
  35. ncbi Thyroxine treatment induces upregulation of renin-angiotensin-aldosterone system due to decreasing effective plasma volume in patients with primary myxoedema
    C W Park
    Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, 62 Yoido-Dong, Youngdungpo-ku, Seoul 150-713, Korea
    Nephrol Dial Transplant 16:1799-806. 2001
    ..3 months (range, 3-9 months) to normalize thyroid function. The mean reductions of body weight and estimated plasma volume were 1.8+/-1.0 kg (P=0.002) and 8.5% (P<0.001), respectively...
  36. doi A physicochemical approach to acid-base balance in critically ill trauma patients minimizes errors and reduces inappropriate plasma volume expansion
    Lewis J Kaplan
    Department of Surgery, Section of Trauma, Surgical Critical Care and Surgical Emergencies, Yale University School of Medicine, New Haven, Connecticut 06518, USA
    J Trauma 66:1045-51. 2009
    ..This study assesses if a physicochemical (PC) approach to acid-base balance improves the accuracy of acid-base diagnosis, and reduces inappropriate fluid loading...
  37. ncbi Time course variations of haemodynamics, plasma volume and microvascular fluid exchange following surface cooling: an experimental approach to accidental hypothermia
    Stig Morten Hammersborg
    Department of Anaesthesia and Intensive Care, Institute for Surgical Sciences, University of Bergen, Haukeland University Hospital, 5021 Bergen, Norway
    Resuscitation 65:211-9. 2005
    ..To describe how surface cooling influences fluid distribution, vascular capacity and haemodynamic variables...
  38. ncbi Plasma volume expansion in early pregnancy
    I M Bernstein
    Department of Obstetrics and Gynecology, University of Vermont College of Medicine, Burlington, Vermont, USA
    Obstet Gynecol 97:669-72. 2001
    To determine the time course of plasma volume expansion in early pregnancy.
  39. pmc Plasma volume and outcome in pulmonary hypertension
    Karen B James
    Department of Cardiovascular Medicine, Cleveland Clinic, Kaufman Center for Heart Failure, Cleveland, Ohio 44195, USA
    Tex Heart Inst J 30:305-7. 2003
    ..However, the effect of plasma volume on outcome has not been evaluated...
  40. ncbi In vivo mapping of fractional plasma volume (fpv) and endothelial transfer coefficient (Kps) in solid tumors using a macromolecular contrast agent: correlation with histology and ultrastructure
    Pasquina Marzola
    Dipartimento di Scienze Morfologico Biomediche, Sezione di Anatomia ed Istologia, Universita di Verona, Verona, Italy
    Int J Cancer 104:462-8. 2003
    ..were acquired before and after administration of Gd-DTPA-albumin to obtain parametric maps of fractional plasma volume (fpv) and transendothelial permeability (Kps)...
  41. ncbi Time course of maternal plasma volume and hormonal changes in women with preeclampsia or fetal growth restriction
    Sofia P Salas
    Department of Obstetrics and Gynecology, School of Medicine Pontificia Universidad Católica de Chile, Sandiago, Chile
    Hypertension 47:203-8. 2006
    ..hormones, such as aldosterone and estradiol, either preceding or concomitant with the onset of the reduced plasma volume described in these women...
  42. ncbi Plasma volume expansion by albumin in cirrhosis. Relation to blood volume distribution, arterial compliance and severity of disease
    Kim Brinch
    Department of Clinical Physiology, 239, Hvidovre Hospital, University of Copenhagen, DK 2650 Hvidovre, Denmark
    J Hepatol 39:24-31. 2003
    ..The aim of the study was to investigate the effect of a standard albumin load on blood volume distribution, arterial compliance, and the renin-angiotensin-aldosterone system in patients with different degrees of cirrhosis...
  43. ncbi Does albumin and furosemide therapy affect plasma volume in nephrotic children?
    Z Bircan
    Kartal Training and Research Hospital, Istanbul, Turkey
    Pediatr Nephrol 16:497-9. 2001
    Albumin infusions transiently increase plasma volume (PV) and oncotic pressure, and may restore diuretic responsiveness in nephrotic edema...
  44. ncbi Influence of hydrostatic pressure gradients on regulation of plasma volume after exercise
    G W Mack
    John B Pierce Laboratory and Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    J Appl Physiol (1985) 85:667-75. 1998
    ..During exercise, plasma volume (PV) decreased by 5.7 +/- 0.7 and 7. 0 +/- 0...
  45. ncbi Early effects of oral salt on plasma volume, orthostatic tolerance, and baroreceptor sensitivity in patients with syncope
    B L Mtinangi
    Institute for Cardiovascular Research, University of Leeds, UK
    Clin Auton Res 8:231-5. 1998
    Salt loading of patients with orthostatic-related syncope has been shown to increase plasma volume and orthostatic tolerance and to decrease baroreceptor sensitivity...
  46. ncbi Plasma volume changes associated with two hydroxyethyl starch colloids following acute hypovolaemia in volunteers
    M F M James
    Centre for Anaesthesia, University College London, London, UK
    Anaesthesia 59:738-42. 2004
    ..colloid preparations, one a high molecular weight and the other a low molecular weight preparation, on the plasma volume changes over time...
  47. ncbi Does indocyanine green accurately measure plasma volume independently of its disappearance rate from plasma in critically ill patients?
    H Ishihara
    Department of Anesthesiology, University of Hirosaki School of Medicine, Japan
    Intensive Care Med 25:1252-8. 1999
    To determine whether plasma volume determined by the indocyanine green (ICG) dilution method (PV-ICG) is equally accurate independently of its disappearance rate from plasma in the critically ill.
  48. pmc Atrial natriuretic peptide: an essential physiological regulator of transvascular fluid, protein transport, and plasma volume
    Fitz Roy E Curry
    Department of Physiology and Membrane Biology, School of Medicine, University of California Davis, Davis, California 95616, USA
    J Clin Invest 115:1458-61. 2005
    Atrial natriuretic peptide (ANP) acts acutely to reduce plasma volume by at least 3 mechanisms: increased renal excretion of salt and water, vasodilation, and increased vascular permeability...
  49. ncbi Plasma volume restoration with salt tablets and water after bed rest prevents orthostatic hypotension and changes in supine hemodynamic and endocrine variables
    Wendy W Waters
    Human Adaptation and Countermeasures Office, Wyle Laboratories, Inc, Houston, Texas, USA
    Am J Physiol Heart Circ Physiol 288:H839-47. 2005
    ..We hypothesized that restoring plasma volume with salt tablets and water after 12 days of head-down bed rest would result in an absence of hemodynamic and ..
  50. ncbi Colloids versus crystalloids and tissue oxygen tension in patients undergoing major abdominal surgery
    K Lang
    Department of Anesthesiology and Intensive Care Medicine, Klinikum der Stadt Ludwigshafen, Bremserstr. 79, D-67063 Ludwigshafen, Germany
    Anesth Analg 93:405-9 , 3rd contents page. 2001
    ..The ptiO(2) increased in the HES-treated (+59%) but decreased in the RL-treated (-23%) patients. Improved microcirculation may be the mechanism for the better ptiO(2) in the HES group...
  51. ncbi Regional cerebral plasma volume response to carbon dioxide using magnetic resonance imaging
    J F Payen
    INSERM U438, Hopital Albert Michallon, Grenoble, France
    Anesthesiology 88:984-92. 1998
    ..Using steady state contrast-enhanced magnetic resonance imaging, the authors determined regional changes in cerebral plasma volume (CPV) induced by hypercapnia in halothane-anesthetized rats.
  52. ncbi Long-term exposure to intermittent hypoxia results in increased hemoglobin mass, reduced plasma volume, and elevated erythropoietin plasma levels in man
    Katja Heinicke
    Division of Physiology, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla 92093 0623A, USA
    Eur J Appl Physiol 88:535-43. 2003
    ..b>Plasma volume (PV) and blood volume (BV) decreased at altitude but increased when OI and SI returned to sea level...
  53. pmc Initial distribution volume of glucose can be approximated using a conventional glucose analyzer in the intensive care unit
    Hironori Ishihara
    Department of Anesthesiology, University of Hirosaki School of Medicine, Hirosaki Shi, Japan
    Crit Care 9:R144-9. 2005
    ..The purpose of the present study was to compare approximated IDVG, derived from just two blood samples, versus original IDVG, and to test whether approximated IDVG is an acceptable alternative measure of IDVG in the intensive care unit...
  54. ncbi Red cell mass and plasma volume measurements in polycythemia: evaluation of performance and practical utility
    Shireen Sirhan
    Division of Hematology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 104:213-5. 2005
    ....
  55. ncbi Does indocyanine green accurately measure plasma volume early after cardiac surgery?
    Hironori Ishihara
    Department of Anesthesiology, University of Hirosaki School of Medicine, Hirosaki Shi, Japan
    Anesth Analg 94:781-6, table of contents. 2002
    Potential overestimation of plasma volume (PV) determination by the conventional indocyanine green (ICG) dilution method (PV-ICG) can occur when generalized capillary protein leakage is present, because ICG binds to proteins...
  56. ncbi Plasma volume measurement in septic patients using an albumin dilution technique: comparison with the standard radio-labelled albumin method
    Michael P Margarson
    Magill Department of Anaesthesia, Chelsea and Westminster Hospital, 369 Fulham Road, London, SW10 3NH, UK
    Intensive Care Med 31:289-95. 2005
    To investigate a technique using 20% albumin for measurement of plasma volume in critically ill patients.
  57. ncbi Plasma volume and blood pressure regulation in hypertensive pregnancy
    Wessel Ganzevoort
    Department of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The Netherlands
    J Hypertens 22:1235-42. 2004
    ..Pre-eclampsia is a multisystem disorder, peculiar to and frequent in human pregnancy. It remains a leading cause of maternal and neonatal morbidity and mortality. Hemodynamic disturbances are the most prominent features of the syndrome...
  58. ncbi Possible overestimation of indocyanine green-derived plasma volume early after induction of anesthesia with propofol/fentanyl
    Wei Dong Mi
    Department of Anesthesiology, University of Hirosaki School of Medicine, Hirosaki Shi, Japan
    Anesth Analg 97:1421-7. 2003
    ..9%, 2.2%, and 2.3%, respectively (P < 0.05). Percentile increase in plasma volume calculated from Hb and Hct before and after induction was 4%...
  59. ncbi Can initial distribution volume of glucose predict hypovolemic hypotension after radical surgery for esophageal cancer?
    A Suzuki
    Department of Anesthesiology, University of Hirosaki School of Medicine, 5 Zaifu cho, Hirosaki Shi, 036 8562, Japan
    Anesth Analg 92:1146-51. 2001
    ..IDVG and plasma volume were calculated after measuring cardiac index (CI), central venous pressure, and pulmonary artery wedge ..
  60. ncbi Comparison of initial distribution volume of glucose and plasma volume in thoracic fluid-accumulated patients
    H Ishihara
    Department of Anesthesiology, University of Hirosaki School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    Crit Care Med 29:1532-8. 2001
    ..The purpose of this study was to describe changes in initial distribution volume of glucose, plasma volume determined by the indocyanine green dilution method (PV-ICG), and thoracic fluid content by thoracic ..
  61. ncbi The initial distribution volume of glucose rather than indocyanine green derived plasma volume is correlated with cardiac output following major surgery
    H Ishihara
    Department of Anesthesiology, University of Hirosaki School of Medicine, Japan
    Intensive Care Med 26:1441-8. 2000
    To determine whether the initial distribution volume of glucose (IDVG) rather than plasma volume or blood volume is correlated better with cardiac output during the 4 days following major surgery.
  62. ncbi Effect of endothelin on plasma volume and albumin escape
    R S Zimmerman
    Division of Research, Alton Ochsner Medical Foundation, New Orleans, LA 70121
    Circ Res 70:1027-34. 1992
    ..Red blood cell volume and plasma volume were determined by using chromium-51-labeled erythrocytes and iodine-125-labeled albumin, respectively, in ..
  63. ncbi Effects of exercise on the secondary blood markers commonly used to suspect erythropoietin doping
    Neil Robinson
    Laboratoire Suisse d Analyse du Dopage, Institut Universitaire de Medecine Legale, Lausanne, Switzerland
    Clin Lab 49:57-62. 2003
    ..the necessity of taking pre-analytical precautions to avoid possible suspicious results coming from major plasma volume changes caused notably by dehydration...
  64. ncbi Head down tilt at -6 degrees to -24 degrees can neutralize the cardiovascular effects of LBNP at -15 or -35 mmHg
    Helmut Hinghofer-Szalkay
    Institute for Adaptive and Spaceflight Physiology, Graz, Austria
    Aviat Space Environ Med 75:947-51. 2004
    ....
  65. ncbi Exercise with the intensity of the individual anaerobic threshold in acute hypoxia
    Birgit Friedmann
    Department of Sports Medicine, Medical Clinic and Policlinic, University of Heidelberg, Germany
    Med Sci Sports Exerc 36:1737-42. 2004
    ..15) defines equivalent relative submaximal intensities in these environmental conditions...
  66. ncbi Effect of hypervolemia on heart rate during 4 days of prolonged exercises
    R Mounier
    Laboratoire de Biologie des Activités Physiques et Sportives, Faculte de Medecine, Clermont Ferrand, France
    Int J Sports Med 24:523-9. 2003
    The aim was to evaluate the cardiodynamic adjustment during 4 days of prolonged exercises and to check if the plasma volume (PV) expansion which is observed generally during such events plays a role in this adaptation...
  67. ncbi Elastic stockings, performance and leg pain recovery in 63-year-old sportsmen
    J C Chatard
    Laboratoire de Physiologie, GIP Exercice, Faculte de Medecine, Universite de Saint Etienne, Pavilion 91, Bellevue, 42 055 Saint Etienne 2, France
    Eur J Appl Physiol 93:347-52. 2004
    ..ECS exerted a 44 hPa pressure at the ankle. Blood lactate concentrations, hematocrit, and plasma volume were measured after a 60-min rest and every 20 min during recovery...
  68. ncbi Fluid-regulatory hormone responses during cycling exercise in acute hypobaric hypoxia
    Olivier Bocqueraz
    Department of Human Factors, National Health Research Center for Defense, CRSSA, La Tronche, France
    Med Sci Sports Exerc 36:1730-6. 2004
    ....
  69. ncbi Renal and hormonal responses to isotonic saline infusion after 3 days' head-down tilt vs. supine and seated positions
    P Mauran
    Department de Physioloogie de la Faculté de Médecine de Reims, American Memorial Hospital, France
    Acta Physiol Scand 177:167-76. 2003
    ..The study aimed to determine whether prolonged exposure to simulated microgravity produces a level of thoracic volume receptor loading similar to that seen in the upright position or immediately after lying down...
  70. ncbi The effect of acute plasma volume expansion on venous capacitance
    Y N Boutcher
    De Montfort University, Bedford, UK
    J Sports Med Phys Fitness 43:105-10. 2003
    The purpose of this study was to examine the effect of plasma volume (PV) expansion, induced by 1 single bout of high intensity exercise, on venous capacitance.
  71. ncbi Effect of dietary sodium on fluid/electrolyte regulation during bed rest
    W Jon Williams
    Wyle Laboratories Life Sciences, Systems and Services, Houston, TX, USA
    Aviat Space Environ Med 74:37-46. 2003
    A negative fluid balance during bed rest (BR) is accompanied by decreased plasma volume (PV) which contributes to cardiovascular deconditioning.
  72. pmc Chronic angiotensin II infusion attenuates the renal sympathoinhibitory response to acute volume expansion
    Lila P LaGrange
    Department of Physiology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Am J Physiol Regul Integr Comp Physiol 284:R1098-107. 2003
    ....
  73. ncbi Does resistance exercise prevent body fluid changes after a 90-day bed rest?
    Eric Belin de Chantemele
    Laboratoire de Physiologie de l Environnement, Faculte de Medecine, Lyon Grange Blanche, 8 avenue Rockefeller, 69373, Lyon, Cedex 08, France
    Eur J Appl Physiol 92:555-64. 2004
    ..Total body water (TBW, measured by isotope dilution) and plasma volume (PV, calculated from the haemoglobin and the haematocrit) were measured in a control group (Co, n=9) and a ..
  74. ncbi Rate and amplitude of adaptation to two intensities of exercise in men aged 65-75 yr
    Gregory Gass
    School of Physiotherapy and Exercise Science, Griffith University, Gold Coast, Queensland, Australia
    Med Sci Sports Exerc 36:1811-8. 2004
    ....
  75. ncbi Hemodynamic monitoring in high-risk obstetrics patients, I. Expected hemodynamic changes in pregnancy
    Elizabeth J Bridges
    59th Clinical Research Squadron, 59th Medical Wing, Lackland AFB, San Antonio, Tex, USA
    Crit Care Nurse 23:53-62. 2003
  76. ncbi Effects of human pregnancy on fluid regulation responses to short-term exercise
    Aaron P Heenan
    School of Physical and Health Education, Queen s University, Kingston, Ontario, Canada K7L 3N6
    J Appl Physiol 95:2321-7. 2003
    ..This was attributed to the significantly augmented fluid volume state already present at rest in late gestation...
  77. ncbi Effect of prolonged exercise and carbohydrate on total neutrophil elastase content
    Nicolette C Bishop
    School of Sport and Exercise Sciences, Loughborough University, Loughborough, United Kingdom
    Med Sci Sports Exerc 35:1326-32. 2003
    ....
  78. ncbi Blood rheological responses to running and cycling: a potential effect on the arterial hypoxemia of highly trained athletes?
    O Galy
    UPRES EA 3596, Laboratoire ACTES, UFR STAPS Antilles Guyane, Pointe a Pitre, France
    Int J Sports Med 26:9-15. 2005
    ..H), blood viscosity (etab), plasma viscosity (etapl), index of erythrocyte rigidity (Tk), changes in plasma volume (DeltaPV), pulmonary diffusing capacity (DLco), and arteriolized blood gas (PaO2) were measured before and ..
  79. ncbi Acute hypervolaemia improves arterial oxygen pressure in athletes with exercise-induced hypoxaemia
    Gerald S Zavorsky
    Department of Experimental Medicine, University of British Columbia, Vancouver Hospital and Health Sciences Center, Koerner Pavillion, S154, 2211 Wesbrook Mall, Vancouver, BC, Canada V6T 1Z3
    Exp Physiol 88:555-64. 2003
    The aim of this study was to determine the effect of acute plasma volume expansion on arterial blood-gas status during 6...
  80. pmc Effects of short-term training on plasma acid-base balance during incremental exercise in man
    Charles T Putman
    Exercise Biochemistry Laboratory, Faculty of Physical Education, University of Alberta, Edmonton, Canada
    J Physiol 550:585-603. 2003
    ..in [SID]a, secondary to lower [Cl-]a and [Lac-]a; and second, to a reduction in [Atot]a, due to greater plasma volume and less plasma water flux (Jv) into leg muscle (P<0.05)...
  81. ncbi Plasma lactate and plasma volume recovery in adults and children following high-intensity exercises
    S Berthoin
    Laboratoire d Etudes de la Motricite Humaine, Faculte des Sciences du Sport et de l Education Physique, Universite de Lille, Ronchin, France
    Acta Paediatr 92:283-90. 2003
    To compare plasma lactate concentration recovery kinetics when measured and corrected for variations in plasma volume between children and adults.
  82. ncbi Cardiovascular drift is related to reduced maximal oxygen uptake during heat stress
    Jonathan E Wingo
    Department of Exercise Science, Ramsey Center, 300 River Road, University of Georgia, Athens, GA 30602, USA
    Med Sci Sports Exerc 37:248-55. 2005
    ....
  83. ncbi A subnormal plasma volume in formerly preeclamptic women is associated with a low venous capacitance
    Robert Aardenburg
    Department of Obstetrics and Gynecology, University Hospital Maastricht, Maastricht, The Netherlands
    J Soc Gynecol Investig 12:107-11. 2005
    Pregnancy induces a smaller rise in plasma volume in formerly preeclamptic women with a pre-existent subnormal plasma volume than in their counterparts with a normal plasma volume...
  84. ncbi Comparison of effects of exercise and diuretic on left ventricular geometry, mass, and insulin resistance in older hypertensive adults
    Morton R Rinder
    Applied Physiology Section and Cardiovascular Division, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Physiol Regul Integr Comp Physiol 287:R360-8. 2004
    ..Unlike hydrochlorothiazide, exercise training can improve insulin resistance and aerobic capacity in older hypertensive people...
  85. ncbi Regional hemodynamics during postexercise hypotension. I. Splanchnic and renal circulations
    Mollie P Pricher
    Department of Human Physiology, University of Oregon, Eugene, OR 97403 1240, USA
    J Appl Physiol 97:2065-70. 2004
    ..Thus the splanchnic and renal vascular beds neither directly contribute to nor attenuate postexercise hypotension...
  86. ncbi The role of chloride in deoxycorticosterone hypertension: selective sodium loading by diet or drinking fluid
    J Kunes
    Center for Experimental Cardiovascular Research, Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Physiol Res 53:149-54. 2004
    ..However, the absence of a significant plasma volume expansion together with hypernatremia and increased plasma osmolality suggest a considerable degree of ..
  87. ncbi Change in plasma volume during peak exercise in patients with cyanotic congenital heart disease after definitive operation
    Hideo Ohuchi
    Department of Pediatrics, National Cardiovascular Center, Fujishiro dai, Suita, Osaka 565 8565, Japan
    Int J Cardiol 108:216-23. 2006
    To evaluate changes in plasma volume (deltaPV) during exercise in patients with single ventricular physiology with cyanosis; post-Fontan patients; and in patients after right ventricular outflow tract reconstruction (RVOTR).
  88. ncbi The effects of dehydration on brain volume -- preliminary results
    J M Dickson
    Department of Biomedical Science, The University of Sheffield, Sheffield, UK
    Int J Sports Med 26:481-5. 2005
    ..932, p=0.007). The changes in ventricular volume caused by dehydration were much larger than those seen in day-to-day fluctuations in a normally hydrated healthy control subject...
  89. ncbi Prolonged exercise following diuretic-induced hypohydration effects on fluid and electrolyte hormones
    B D Roy
    Department of Kinesiology, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, N2L 3G1 Canada
    Horm Metab Res 33:540-7. 2001
    To investigate the hypothesis that a reduction in plasma volume (PV) induced by diuretic administration would result in an increase in the fluid and electrolyte hormonal response to exercise, ten untrained males (VO(2) peak = 3.96 +/- 0...
  90. ncbi Benefit of repeated receptor stimulation as a spaceflight medical tool to promote cardiovascular fitness: different orthostatic paradigms compared
    Helmut Hinghofer-Szalkay
    Institute of Physiology, Medical University, Harrachgasse 21, A 8010 Graz, Austria
    Curr Pharm Biotechnol 6:253-66. 2005
    ..Therefore, one of the questions asked in this study were if movement between the two defined body positions produces similar changes when employing Protocol X vs. Protocol Y...
  91. ncbi Formerly preeclamptic women with a subnormal plasma volume are unable to maintain a rise in stroke volume during moderate exercise
    Robert Aardenburg
    Department of Obstetrics and Gynecology, University Hospital Maastricht, Maastricht, The Netherlands
    J Soc Gynecol Investig 12:599-603. 2005
    In formerly preeclamptic women with a low plasma volume, the recurrence rate of preeclampsia is higher than in women with a normal prepregnant plasma volume...
  92. ncbi Effect of centrifuge-induced artificial gravity and ergometric exercise on cardiovascular deconditioning, myatrophy, and osteoporosis induced by a -6 degrees head-down bedrest
    Satoshi Iwase
    Dept Physiol II, Aichi Med Univ, Aichi, Japan
    J Gravit Physiol 11:P243-4. 2004
    ..The combination of high/low G-load with low/high intensity exercise will determine the optimal protocol for prevention of cardiovascular deconditioning, myatrophy, and osteoporosis...
  93. ncbi Acute plasma volume expansion in the untrained alters the hormonal response to prolonged moderate-intensity exercise
    B D Roy
    Dept. of Kinesiology, University of Waterloo, ON, Canada
    Horm Metab Res 33:238-45. 2001
    To investigate the role of an increase in plasma volume (PV), characteristically observed with short-term endurance training, on the endocrine response to prolonged moderate intensity exercise, eight untrained males (VO2 peak = 3...
  94. ncbi Splenic denervation worsens lipopolysaccharide-induced hypotension, hemoconcentration, and hypovolemia
    P S Andrew
    Departments of Physiology and Medicine, University of Alberta, Edmonton, Alberta T6G 2S2, Canada
    Am J Physiol Regul Integr Comp Physiol 280:R1564-72. 2001
    ..LPS)-induced endotoxemia, increased intrasplenic fluid efflux contributes to a reduction in plasma volume. We hypothesized that splenic sympathetic nerve activity (SSNA), which increases during endotoxemia, limits ..
  95. ncbi Genomic and non-genomic effects of aldosterone on the individual variation of the sweat Na+ concentration during exercise in trained athletes
    Tetsuya Yoshida
    Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto, 606 8585, Japan
    Eur J Appl Physiol 98:466-71. 2006
    ..As a result, the genomic action of ALD may be affected more by the sweat Na+ variation than by the rapidly non-genomic action during exercise in humans...
  96. ncbi Total haemoglobin mass and spleen contraction: a study on competitive apnea divers, non-diving athletes and untrained control subjects
    Nicole Prommer
    Arbeitsbereich Sportmedizin, Universitat, 95440, Bayreuth, Germany
    Eur J Appl Physiol 101:753-9. 2007
    ..tHb-mass and plasma volume were measured using the CO-rebreathing method...
  97. ncbi Chronic activation of plasma renin is log-linearly related to dietary sodium and eliminates natriuresis in response to a pulse change in total body sodium
    Mads Kjolby
    Department of Physiology and Pharmacology, Institute of Medical Biology, University of Southern Denmark, Odense, Denmark
    Am J Physiol Regul Integr Comp Physiol 294:R17-25. 2008
    ..that sodium excretion is controlled by neurohumoral mechanisms that are quite resistant to acute changes in plasma volume and colloid osmotic pressure and are not down-regulated within 2 h...
  98. ncbi Angiotensin-(1-7) serves as an aquaretic by increasing water intake and diuresis in association with downregulation of aquaporin-1 during pregnancy in rats
    J Joyner
    Hypertension and Vascular Research Center, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1032, USA
    Am J Physiol Regul Integr Comp Physiol 294:R1073-80. 2008
    ..In virgin and pregnant animals, A-779 administration had no effect on blood pressure, plasma volume, blood volume, or urinary electrolytes...
  99. doi Intensity and physiological strain of competitive ultra-endurance exercise in humans
    Samuel J E Lucas
    School of Physical Education, University of Otago, Dunedin, New Zealand
    J Sports Sci 26:477-89. 2008
    ..01), and increased plasma volume (25 +/- 10%; P < 0.01) with a stable sodium concentration...
  100. doi The natriuretic and diuretic response to dopamine is maintained during rat pregnancy
    Jennifer M Sasser
    Dept of Physiology and Functional Genomics, Univ of Florida, PO Box 100274, Gainesville, FL 32610, USA
    Am J Physiol Renal Physiol 294:F1342-4. 2008
    During pregnancy, there is a marked plasma volume expansion due to renal sodium retention...
  101. ncbi Change in plasma volume from a state of hyper-, normo- or hypovolemia with or without noradrenalin infusion in the rat
    Maris Dubniks
    Department of Anesthesiology and Intensive Care, University and University Hospital of Lund, Sweden
    Microvasc Res 76:75-9. 2008
    ..The present study on the rat aims at evaluating the change in plasma volume after 2.5 h from a state of hyper- and hypovolemia...

Research Grants76

  1. The baroreflex in pregnancy: effects of adrenal and placental steroids
    Maureen Keller Wood; Fiscal Year: 2010
    ..We have found that reduction in maternal cortisol results in a deficiency in the normal expansion of maternal plasma volume. This model also causes reduced fetal blood pressure and increased incidence of fetal hypoxia and fetal and ..
  2. The baroreflex in pregnancy: effects of adrenal and placental steroids
    Maureen Keller Wood; Fiscal Year: 2009
    ..We have found that reduction in maternal cortisol results in a deficiency in the normal expansion of maternal plasma volume. This model also causes reduced fetal blood pressure and increased incidence of fetal hypoxia and fetal and ..
  3. HEMODYNAMIC & AUTONOMIC MECHANISMS OF SYNCOPE SUSCEPTIBILITY IN CFS
    Barry Hurwitz; Fiscal Year: 1999
    ..b>Plasma volume expansion is associated with a reduction or resolution of orthostatic hypotensive symptoms in some but not all ..
  4. HEMATOCRIT & BLOOD VOLUME--EFFECTS OF MAXIMAL 02 INTAKE
    Robert Johnson; Fiscal Year: 1999
    ..Maximal O2 uptake (VO2max); circulating plasma volume and Hct at rest and heavy exercise. 2...
  5. HYPOTHALAMIC OPIATES IN OBESITY-ACCELERATED HYPERTENSION
    Robin Rockhold; Fiscal Year: 1990
    ..abnormalities associated with obesity-accelerated hypertension will be identified by measuring alterations in plasma volume (radio-iodinated serum albumin dilution) and baroreflex sensitivity in conscious, unrestrained rats following ..
  6. ROLE OF CHLORIDE IN SODIUM-DEPENDENT HYPERTENSION
    Theodore Kurtz; Fiscal Year: 1990
    ..The changes in body weight, extracellular fluid volume, plasma volume, external balances of minerals and electrolytes, and plasma concentrations of renin, aldosterone, ..
  7. MATERNAL DEHYDRATION--FETAL/AMNIOTIC FLUID HOMEOSTASIS
    Michael Ross; Fiscal Year: 2002
    ..Long term studies will examine the effects of hyponatremia on ovine AF volume, maternal plasma volume and umbilical and uterine blood flows in both normal and oligohydramnios ovine pregnancies...
  8. MATERNAL DEHYDRATION--FETAL/AMNIOTIC FLUID HOMEOSTASIS
    Michael Ross; Fiscal Year: 2000
    ..Long term studies will examine the effects of hyponatremia on ovine AF volume, maternal plasma volume and umbilical and uterine blood flows in both normal and oligohydramnios ovine pregnancies...
  9. MATERNAL DEHYDRATION--FETAL/AMNIOTIC FLUID HOMEOSTASIS
    Michael Ross; Fiscal Year: 1999
    ..Long term studies will examine the effects of hyponatremia on ovine AF volume, maternal plasma volume and umbilical and uterine blood flows in both normal and oligohydramnios ovine pregnancies...
  10. MATERNAL DEHYDRATION--FETAL/AMNIOTIC FLUID HOMEOSTASIS
    Michael Ross; Fiscal Year: 2001
    ..Long term studies will examine the effects of hyponatremia on ovine AF volume, maternal plasma volume and umbilical and uterine blood flows in both normal and oligohydramnios ovine pregnancies...
  11. Aldosterone and Sodium Regulation in Postural Tachycardia Syndrome
    Satish R Raj; Fiscal Year: 2012
    ..We have found low plasma volume in the majority of patients with POTS. This can trigger the sympathetic activation that drives the tachycardia...
  12. HYPOPROTEINEMIA AND MODULATION OF VASCULAR FILTRATION
    Bruce Harms; Fiscal Year: 1992
    b>Plasma volume expanders are often required in the management of critical care patients, who are frequently hypoproteinemic, or who have sepsis- induced increases in microvascular permeability...
  13. Aldosterone and Sodium Regulation in Postural Tachycardia Syndrome
    Satish R Raj; Fiscal Year: 2010
    ..We have found low plasma volume in the majority of patients with POTS. This can trigger the sympathetic activation that drives the tachycardia...
  14. Targeted Overexpression and Ablation of Renin in Connecting Tubule
    Jean Marc Lalouel; Fiscal Year: 2007
    ..The work should help defining the physiological role of CNT renin in sodium balance, plasma volume and arterial pressure regulation...
  15. Keratin biomaterial-based fluid for trauma resuscitation
    LUKE RUSSELL BURNETT; Fiscal Year: 2012
    ..These include the ability to restore plasma volume, microcirculation, and oxygen delivery as well as practical items such as a low cost, low to no side effects, ..
  16. CONTROL OF SODIUM INTAKE IN THE HINDLIMB UNWEIGHTED RAT
    J Cunningham; Fiscal Year: 2003
    ..HU results in a central movement of body fluid, diuresis and natriuresis, resulting in a decrease in plasma volume. We have observed that rats increase ingestion of saline solution during 24h HU...
  17. CONTROL OF SODIUM INTAKE IN THE HINDLIMB UNWEIGHTED RAT
    J Cunningham; Fiscal Year: 2001
    ..HU results in a central movement of body fluid, diuresis and natriuresis, resulting in a decrease in plasma volume. We have observed that rats increase ingestion of saline solution during 24h HU...
  18. Neural and non-neural modulators of skin blood flow and sweating in humans
    CRAIG CRANDALL; Fiscal Year: 2007
    ..Moreover, profuse sweating that occurs during heat stress contributes to impaired blood pressure control if plasma volume is sufficiently reduced...
  19. Neural and non-neural modulators of skin blood flow and sweating in humans
    CRAIG CRANDALL; Fiscal Year: 2009
    ..Moreover, profuse sweating that occurs during heat stress contributes to impaired blood pressure control if plasma volume is sufficiently reduced...
  20. Neural and non-neural modulators of skin blood flow and sweating in humans
    CRAIG CRANDALL; Fiscal Year: 2006
    ..Moreover, profuse sweating that occurs during heat stress contributes to impaired blood pressure control if plasma volume is sufficiently reduced...
  21. Prepregnancy Phenotype and Predisposition to Preeclampsia
    IRA MARK BERNSTEIN; Fiscal Year: 2010
    ..We suggested that low prepregnancy plasma volume was an important marker for those at risk and that volume expansion was the critical pregnancy specific ..
  22. CARDIAC RECEPTOR ACTIVITY IN PREGNANCY
    Mary Hines; Fiscal Year: 1999
    b>Plasma volume expands by approximately 50% in normal pregnancy...
  23. VASOTOCIN RECEPTORS
    PATRICK EGGENA; Fiscal Year: 1990
    The antidiuretic hormone, vasopressin (AVP), plays an important role in the regulation of plasma volume and osmolality by triggering the reabsorption of water, urea, and sodium from the forming uring in the kidney...
  24. DETERMINANTS OF SODIUM RETENTION IN CIRRHOSIS
    WILLIAM RECTOR; Fiscal Year: 1992
    ..hypothesis is that renal sodium retention is caused by impaired liver metabolic function, ascites" as plasma volume expands...
  25. DETERMINANTS OF RENAL SODIUM RETENTION IN CIRRHOSIS
    WILLIAM RECTOR; Fiscal Year: 1990
    ..hypothesis is that renal sodium retention is caused by impaired liver metabolic function, ascites" as plasma volume expands...
  26. Studies on Serial Phlebotomy in Voluntary Blood Donors
    Stuart Katz; Fiscal Year: 2009
    ..transient hyperhomocysteinemia, serum and urinary measures of iron stores and oxidative stress, red cell and plasma volume, regional arterial wall shear stress, and erythropoietin levels will be obtained before and after the assigned ..
  27. Studies on Serial Phlebotomy in Voluntary Blood Donors
    Stuart D Katz; Fiscal Year: 2010
    ..transient hyperhomocysteinemia, serum and urinary measures of iron stores and oxidative stress, red cell and plasma volume, regional arterial wall shear stress, and erythropoietin levels will be obtained before and after the assigned ..
  28. CONTROL OF SODIUM INTAKE IN THE HINDLIMB UNWEIGHTED RAT
    J Cunningham; Fiscal Year: 2005
    ..HU results in a central movement of body fluid, diuresis and natriuresis, resulting in a decrease in plasma volume. We have observed that rats increase ingestion of saline solution during 24h HU...
  29. CONTROL OF SODIUM INTAKE IN THE HINDLIMB UNWEIGHTED RAT
    J Cunningham; Fiscal Year: 2003
    ..HU results in a central movement of body fluid, diuresis and natriuresis, resulting in a decrease in plasma volume. We have observed that rats increase ingestion of saline solution during 24h HU...
  30. CONTROL OF SODIUM INTAKE IN THE HINDLIMB UNWEIGHTED RAT
    J Cunningham; Fiscal Year: 2002
    ..HU results in a central movement of body fluid, diuresis and natriuresis, resulting in a decrease in plasma volume. We have observed that rats increase ingestion of saline solution during 24h HU...
  31. CONTROL OF SODIUM INTAKE IN THE HINDLIMB UNWEIGHTED RAT
    J Cunningham; Fiscal Year: 2004
    ..HU results in a central movement of body fluid, diuresis and natriuresis, resulting in a decrease in plasma volume. We have observed that rats increase ingestion of saline solution during 24h HU...
  32. Sodium Transport Inhibitors for Hypertension and Cystic Fibrosis
    Erik Schwiebert; Fiscal Year: 2009
    ..in vascular physiology is that 2 x plasma Na+ concentration equates with normal plasma osmolality and sets plasma volume and blood pressure, the physiological parameter that is elevated in hypertension...
  33. Baroreflex failure: Mechanisms and therapy
    ROSE ROBERTSON; Fiscal Year: 2002
    ..alter baroreflex function in diabetics, utilizing direct assessment of baroreflex function, and blood and plasma volume determination during insulin clamp studies...
  34. Prepregnancy Phenotype & Predisposition to Pre-eclampsia
    Ira Bernstein; Fiscal Year: 2007
    ..One feature is a pre-pregnancy phenotype that includes reduced plasma volume, elevated sympathetic tone, reduced utenne blood flow and enhanced platelet activation...
  35. Prepregnancy Phenotype & Predisposition to Pre-eclampsia
    Ira Bernstein; Fiscal Year: 2004
    ..One feature is a pre-pregnancy phenotype that includes reduced plasma volume, elevated sympathetic tone, reduced utenne blood flow and enhanced platelet activation...
  36. Prepregnancy Phenotype & Predisposition to Pre-eclampsia
    Ira Bernstein; Fiscal Year: 2006
    ..One feature is a pre-pregnancy phenotype that includes reduced plasma volume, elevated sympathetic tone, reduced utenne blood flow and enhanced platelet activation...
  37. Prepregnancy Phenotype & Predisposition to Pre-eclampsia
    Ira Bernstein; Fiscal Year: 2005
    ..One feature is a pre-pregnancy phenotype that includes reduced plasma volume, elevated sympathetic tone, reduced utenne blood flow and enhanced platelet activation...
  38. NUCLEAR DIAGNOSTIC METHODS FOR RENAL DISEASE
    JOHN MC AFEE; Fiscal Year: 1990
    ..Because of the abnormal capillary permeability and resultant fluid shift from plasma volume to extravascular spaces, conventional measurements of GFR and ERPF by single injection of c-99m DTPA and I-131 ..
  39. Exppression and function of two paracrine hormonal regulation of nephron
    Jean Marc Lalouel; Fiscal Year: 2001
    ..balance will be disrupted by manipulations of dietary sodium with concordant or discordant alteration of plasma volume; (2) segmental sodium and fluid delivery at various sites along the nephron will be manipulated by selective ..
  40. Exppression and function of two paracrine hormonal regulation of nephron
    Jean Marc Lalouel; Fiscal Year: 2005
    ..balance will be disrupted by manipulations of dietary sodium with concordant or discordant alteration of plasma volume; (2) segmental sodium and fluid delivery at various sites along the nephron will be manipulated by selective ..
  41. HORMONAL-SYMPATHETIC INTERACTIONS IN HYPERTENSION
    John Osborn; Fiscal Year: 1993
    ..b>Plasma volume and systemic hemodynamics will be measured before and during increased dietary salt in rats with surgical and ..
  42. Resuscitating Blood-Substituted Hypothermic Dogs
    Hal Sternberg; Fiscal Year: 2004
    ..combining very low temperatures with total exsanguination and blood substitution with BioTime's FDA-approved plasma volume expander Hextend(r)...
  43. Resuscitating Blood-Substituted Hypothermic Dogs
    Hal Sternberg; Fiscal Year: 2005
    ..combining very low temperatures with total exsanguination and blood substitution with BioTime's FDA-approved plasma volume expander Hextend(r)...
  44. Imprint Osmoregulation/Maternally-Dehydrated Offspring
    Mina Desai; Fiscal Year: 2005
    ..such that the female offspring may not appropriately reset their plasma osmolality and adequately expand their plasma volume during their subsequent pregnancies...
  45. Imprint Osmoregulation/Maternally-Dehydrated Offspring
    Mina Desai; Fiscal Year: 2006
    ..such that the female offspring may not appropriately reset their plasma osmolality and adequately expand their plasma volume during their subsequent pregnancies...
  46. Imprint Osmoregulation/Maternally-Dehydrated Offspring
    Mina Desai; Fiscal Year: 2003
    ..such that the female offspring may not appropriately reset their plasma osmolality and adequately expand their plasma volume during their subsequent pregnancies...
  47. Imprint Osmoregulation/Maternally-Dehydrated Offspring
    Mina Desai; Fiscal Year: 2004
    ..such that the female offspring may not appropriately reset their plasma osmolality and adequately expand their plasma volume during their subsequent pregnancies...
  48. Imprint Osmoregulation/Maternally-Dehydrated Offspring
    Mina Desai; Fiscal Year: 2007
    ..such that the female offspring may not appropriately reset their plasma osmolality and adequately expand their plasma volume during their subsequent pregnancies...
  49. CARDIAC AND ARTERIAL BAROREFLEXES IN HEART FAILURE
    Irving Zucker; Fiscal Year: 1991
    ..These studies will be carried out in the basal state and during plasma volume expansion in order to augment sodium excretion...
  50. CARDIAC AND ARTERIAL BAROREFLEXES IN HEART FAILURE
    Irving Zucker; Fiscal Year: 1990
    ..These studies will be carried out in the basal state and during plasma volume expansion in order to augment sodium excretion...
  51. SODIUM CHLORIDE AND HYPERTENSION
    Theodore Kotchen; Fiscal Year: 1990
    ..In the rat and man, we will measure cardiac output, ECF volume, and plasma volume. Sympathetic tone will be assessed by basal and stimulated plasma catecholamines (rat and man), tissue ..
  52. CARDIOVASCULAR PHARMACOLOGY OF ATRIAL NATRIURETIC FACTOR
    ALAN HOLLISTER; Fiscal Year: 1990
    ..We plan to systematically manipulate atrial pressure, test a series of vasoactive agonists and manipulate plasma volume and osmolarity to determine the contribution of each of these stimuli to the regulation of plasma ANF ..
  53. VASCULAR ADAPTATIONS IN PREGNANCY
    SHARON NELSON; Fiscal Year: 1993
    ..hypertension (preeclampsia), is characterized by vascular hyperreactivity, vasoconstriction and a fall in plasma volume. Thus, pregnancy-induced hypertension, in some respects, can be considered a condition in which there is a ..
  54. VASCULAR ADAPTATIONS IN PREGNANCY
    SHARON NELSON; Fiscal Year: 1991
    ..hypertension (preeclampsia), is characterized by vascular hyperreactivity, vasoconstriction and a fall in plasma volume. Thus, pregnancy-induced hypertension, in some respects, can be considered a condition in which there is a ..
  55. Dopamine-B-Hydroxylase in Human Cardiovascular Control
    David Robertson; Fiscal Year: 2006
    ..in neural regulation of blood pressure, while dopamine (DA) plays an important depressor role via renal and plasma volume mechanisms. Dopaminebeta-hydroxylase (DBH) is the enzyme responsible for the conversion of DA to NE...
  56. Dopamine-B-Hydroxylase in Human Cardiovascular Control
    David Robertson; Fiscal Year: 2003
    ..in neural regulation of blood pressure, while dopamine (DA) plays an important depressor role via renal and plasma volume mechanisms. Dopaminebeta-hydroxylase (DBH) is the enzyme responsible for the conversion of DA to NE...
  57. Dopamine-B-Hydroxylase in Human Cardiovascular Control
    David Robertson; Fiscal Year: 2004
    ..in neural regulation of blood pressure, while dopamine (DA) plays an important depressor role via renal and plasma volume mechanisms. Dopaminebeta-hydroxylase (DBH) is the enzyme responsible for the conversion of DA to NE...
  58. Dopamine-B-Hydroxylase in Human Cardiovascular Control
    David Robertson; Fiscal Year: 2005
    ..in neural regulation of blood pressure, while dopamine (DA) plays an important depressor role via renal and plasma volume mechanisms. Dopaminebeta-hydroxylase (DBH) is the enzyme responsible for the conversion of DA to NE...
  59. PRELOAD CHANGE UTILIZING LOW BODY NEGATIVE PRESSURE ON LEFT VENTRICULAR MASS
    Rodney Falk; Fiscal Year: 2000
    ..Whether this is a true decrease or is related to change in circulating plasma volume with a secondary change in the geometry of the heart is unknown...
  60. ROLE OF VASOPRESSIN IN HUMAN HYPERTENSION
    DAVID STREETEN; Fiscal Year: 1980
    ..This will be ascertained by observing the responses in blood pressure, fluid balance, plasma volume and extracellular fluid volume, to the administration of AVP by acute intravenous infusion and by chronic (2 ..
  61. PREVENTION AND TREATMENT OF HUMAN OLIGOHYDRAMNIOS
    Michael Ross; Fiscal Year: 1999
    Early in normal human pregnancy, maternal plasma osmolality decreases and plasma volume increases...
  62. BLOOD VOLUME AND VENOUS RETURN IN THERMAL STRAIN
    ETHAN NADEL; Fiscal Year: 1991
    Uncovering the mechanisms accounting for the plasma volume expansion that occurs with training is the primary, long-term goal of this renewal application...
  63. Sodium Transport Inhibitors for Hypertension and Cystic Fibrosis
    John H Streiff; Fiscal Year: 2010
    ..rule in vascular physiology is that 2x plasma Na+ concentration equates with normal plasma osmolality and sets plasma volume and blood pressure, the physiological parameter that is elevated in hypertension...
  64. Sodium Transport Inhibitors for Hypertension and Cystic Fibrosis
    Erik Schwiebert; Fiscal Year: 2009
    ..rule in vascular physiology is that 2x plasma Na+ concentration equates with normal plasma osmolality and sets plasma volume and blood pressure, the physiological parameter that is elevated in hypertension...
  65. PREVENTION AND TREATMENT OF HUMAN OLIGOHYDRAMNIOS
    Michael Ross; Fiscal Year: 2001
    Early in normal human pregnancy, maternal plasma osmolality decreases and plasma volume increases...
  66. PREVENTION AND TREATMENT OF HUMAN OLIGOHYDRAMNIOS
    Michael Ross; Fiscal Year: 2000
    Early in normal human pregnancy, maternal plasma osmolality decreases and plasma volume increases...
  67. EXERCISE TRAINING AND BARORECEPTOR FUNCTION
    Peter Raven; Fiscal Year: 1990
    ..Endurance exercise training is known to produce an increase in total blood volume, primarily plasma volume and a parasympathetically dominated autonomic nervous system (ANS)...
  68. NEURAL SYSTEMS REGULATING VASOPRESSIN RELEASE
    J Cunningham; Fiscal Year: 2002
    ..Changes in blood pressure, plasma volume, osmolality and the concentration of circulating hormones all influence the activity of vasopressin neurons in ..
  69. NEURAL SYSTEMS REGULATING VASOPRESSIN RELEASE
    J Cunningham; Fiscal Year: 1999
    ..Changes in blood pressure, plasma volume, osmolality and the concentration of circulating hormones all influence the activity of vasopressin neurons in ..