salivation

Summary

Summary: The secretion of saliva which serves to moisten and soften food and keep the mouth moist. (From Dorland, 28th ed)

Top Publications

  1. ncbi Impact of dry mouth and hyposalivation on oral health-related quality of life of elderly Japanese
    Kazunori Ikebe
    Division of Oromaxillofacial Regeneration Osaka University Graduate School of Dentistry, Suita, Osaka, Japan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:216-22. 2007
  2. pmc M(3) muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice
    Takeshi Nakamura
    Calcium Oscillation Project, Japan Science and Technology Agency, Tokyo, Japan
    J Physiol 558:561-75. 2004
  3. ncbi Radiation-induced xerostomia in patients with head and neck cancer: pathogenesis, impact on quality of life, and management
    Mark S Chambers
    Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, USA
    Head Neck 26:796-807. 2004
  4. ncbi Parotid and submandibular/sublingual salivary flow during high dose radiotherapy
    F R Burlage
    Department of Radiotherapy, University Hospital, P.O. Box 30.0019700 RB, Groningen, The Netherlands
    Radiother Oncol 61:271-4. 2001
  5. ncbi Review: The physiology of saliva and transfer of drugs into saliva
    Johan K M Aps
    UZG P8 Department of Paediatric Dentistry and Centre for Special Care, PaeCaMed Research Unit, Ghent University, De Pintelaan 185, 9000 Gent, Belgium
    Forensic Sci Int 150:119-31. 2005
  6. ncbi Development and evaluation of a comprehensive screening for orofacial dysfunction
    Merete Bakke
    Department of Oral Medicine Clinical Oral Physiology, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    Swed Dent J 31:75-84. 2007
  7. ncbi Sialic acid feeding aged rats rejuvenates stimulated salivation and colon enteric neuron chemotypes
    Norbert Sprenger
    Nestle Research Center, Vers chez les Blanc, Lausanne 26, CH 1000 Switzerland
    Glycobiology 19:1492-502. 2009
  8. ncbi Nicotine delivery and subjective effects of Swedish portion snus compared with 4 mg nicotine polacrilex chewing gum
    Erik Lunell
    CROel AB, Helsingborg, Sweden
    Nicotine Tob Res 13:573-8. 2011
  9. ncbi Radiation-induced xerostomia: pathophysiology, clinical course and supportive treatment
    H J Guchelaar
    Department of Clinical Pharmacy, University of Amsterdam, The Netherlands
    Support Care Cancer 5:281-8. 1997
  10. ncbi Salivary dysfunction associated with systemic diseases: systematic review and clinical management recommendations
    Inger von Bültzingslöwen
    Department of Oral Medicine, Sahlgrenska Academy, Goteborg University, Goteborg, Sweden
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:S57.e1-15. 2007

Detail Information

Publications251 found, 100 shown here

  1. ncbi Impact of dry mouth and hyposalivation on oral health-related quality of life of elderly Japanese
    Kazunori Ikebe
    Division of Oromaxillofacial Regeneration Osaka University Graduate School of Dentistry, Suita, Osaka, Japan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:216-22. 2007
    ..To determine the association of hyposalivation and the perception of dry mouth with oral health-related quality of life for independently living elderly...
  2. pmc M(3) muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice
    Takeshi Nakamura
    Calcium Oscillation Project, Japan Science and Technology Agency, Tokyo, Japan
    J Physiol 558:561-75. 2004
    ..However, despite initial reports of salivation abnormalities in M(3)-knockout (M(3)KO) mice, it is still unclear which subtype is functionally relevant in ..
  3. ncbi Radiation-induced xerostomia in patients with head and neck cancer: pathogenesis, impact on quality of life, and management
    Mark S Chambers
    Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, USA
    Head Neck 26:796-807. 2004
    ..Xerostomia is a common, debilitating complication of radiation therapy (RT) for head and neck cancer. This article reviews the pathogenesis of radiation-induced xerostomia, its impact on quality of life (QOL), and treatment options...
  4. ncbi Parotid and submandibular/sublingual salivary flow during high dose radiotherapy
    F R Burlage
    Department of Radiotherapy, University Hospital, P.O. Box 30.0019700 RB, Groningen, The Netherlands
    Radiother Oncol 61:271-4. 2001
    ..Neither recovery nor significant differences were observed between the production of saliva from the parotid and submandibular/sublingual glands during the 13 weeks observation period...
  5. ncbi Review: The physiology of saliva and transfer of drugs into saliva
    Johan K M Aps
    UZG P8 Department of Paediatric Dentistry and Centre for Special Care, PaeCaMed Research Unit, Ghent University, De Pintelaan 185, 9000 Gent, Belgium
    Forensic Sci Int 150:119-31. 2005
    ..Consequently, it can be used in clinically difficult situations, such as in children, handicapped and anxious patients, where blood sampling could be a difficult act to perform...
  6. ncbi Development and evaluation of a comprehensive screening for orofacial dysfunction
    Merete Bakke
    Department of Oral Medicine Clinical Oral Physiology, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    Swed Dent J 31:75-84. 2007
    ..Kappa values for interexaminer agreement on the NOT-S scores were 0.42-0.44 (i.e. fair), and the method error was 5.3%. To conclude, NOT-S gave a reliable and valid screening for orofacial dysfunction...
  7. ncbi Sialic acid feeding aged rats rejuvenates stimulated salivation and colon enteric neuron chemotypes
    Norbert Sprenger
    Nestle Research Center, Vers chez les Blanc, Lausanne 26, CH 1000 Switzerland
    Glycobiology 19:1492-502. 2009
    Old age is linked to numerous changes of body functions such as salivation, gastrointestinal motility, and permeability all linked to central and enteric nervous system decline. Thus, gut motility and barrier functions suffer...
  8. ncbi Nicotine delivery and subjective effects of Swedish portion snus compared with 4 mg nicotine polacrilex chewing gum
    Erik Lunell
    CROel AB, Helsingborg, Sweden
    Nicotine Tob Res 13:573-8. 2011
    ..Snus availability has been claimed to have contributed to the low rates of smoking among Swedish men and made possible the transfer to a less harmful form of nicotine dependence...
  9. ncbi Radiation-induced xerostomia: pathophysiology, clinical course and supportive treatment
    H J Guchelaar
    Department of Clinical Pharmacy, University of Amsterdam, The Netherlands
    Support Care Cancer 5:281-8. 1997
    ..The hypothesis concerning the existence of early apoptotic and late necrotic effects of irradiation on the salivary glands theoretically offers a way of achieving this goal...
  10. ncbi Salivary dysfunction associated with systemic diseases: systematic review and clinical management recommendations
    Inger von Bültzingslöwen
    Department of Oral Medicine, Sahlgrenska Academy, Goteborg University, Goteborg, Sweden
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:S57.e1-15. 2007
    ..The objective of this study was to identify systemic diseases associated with hyposalivation and xerostomia and develop evidence-based management recommendations for hyposalivation/xerostomia...
  11. ncbi Carbachol improves secretion in the early phase after rabbit submandibular gland transplantation
    L Shi
    Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China
    Oral Dis 16:351-9. 2010
    ..To investigate the changes in the muscarinic receptor signaling pathway with submandibular gland (SMG) transplantation and whether carbachol improves secretion in transplanted SMGs...
  12. ncbi Nicotinic acetylcholine receptor alpha5 subunits modulate oxotremorine-induced salivation and tremor
    Ningshan Wang
    Department of Physiology and Pharmacology, Sackler Medical School, Tel Aviv University, Tel Aviv, Israel
    J Neurol Sci 222:87-91. 2004
    ..The alpha5-/- mice showed significantly increased salivation and tremor responses to OXO...
  13. pmc Pavlov's cockroach: classical conditioning of salivation in an insect
    Hidehiro Watanabe
    Graduate School of Life Sciences, Tohoku University, Sendai, Japan
    PLoS ONE 2:e529. 2007
    ..Pavlov reported classical conditioning of salivation in dogs a century ago...
  14. ncbi Efficacy of pilocarpine lozenge for post-radiation xerostomia in patients with head and neck cancer
    S Taweechaisupapong
    Department of Oral Diagnosis, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand
    Aust Dent J 51:333-7. 2006
    ..However, analysis of pilocarpine lozenges for treatment of post-radiation xerostomia in patients with head and neck cancer has not been reported...
  15. ncbi Botulinum toxin injections for children with excessive drooling
    Sharon Hassin-Baer
    Department of Neurology, Chaim Sheba Medical Center, Tel Hashomer, Israel
    J Child Neurol 20:120-3. 2005
    ..These results underscore the need for further studies to establish the efficacy of this treatment in children...
  16. ncbi Comparative evaluation of exocrine muscarinic receptor binding characteristics and inhibition of salivation of solifenacin in mice
    Tomomi Oki
    Department of Pharmacokinetics and Pharmacodynamics, School of Pharmaceutical Sciences, University of Shizuoka, Japan
    Biol Pharm Bull 29:1397-400. 2006
    ..The aim of the present study was to characterize the suppression of cholinergic salivation and exocrine muscarinic receptor binding of solifenacin on oral administration to mice in comparison with those ..
  17. ncbi Saliva and gastrointestinal functions of taste, mastication, swallowing and digestion
    A M Pedersen
    Copenhagen Gerodontological Oral Health Research Centre, Department of Clinical Oral Physiology, Anatomy, Pathology and Medicine, School of Dentistry, Denmark
    Oral Dis 8:117-29. 2002
    ..Finally, pathophysiological considerations of salivary dysfunction in relation to some GI functions are considered...
  18. ncbi Central muscarinic receptors signal pilocarpine-induced salivation
    A C T Takakura
    Department of Physiology and Pathology, School of Dentistry, Paulista State University UNESP, Rua Humaita, 1680, 14801 903, Araraquara, SP, Brazil
    J Dent Res 82:993-7. 2003
    ..cholinergic agonists such as pilocarpine injected peripherally can act directly on salivary glands to induce salivation, it is possible that their action in the brain may contribute to salivation...
  19. ncbi The cholinesterase inhibitor physostigmine for the local treatment of dry mouth: a randomized study
    Nina Khosravani
    Section of Pharmacology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Goteborg, Sweden
    Eur J Oral Sci 117:209-17. 2009
    ..Physostigmine, applied locally, therefore appears to be a promising modality for dry-mouth treatment...
  20. ncbi Unstimulated salivary flow rate, pH and buffer capacity of saliva in healthy volunteers
    C Fenoll-Palomares
    Medicina Familiar y Comunitaria, Centro de Atención Primaria, Rafelbunyol, Valencia, Spain
    Rev Esp Enferm Dig 96:773-83. 2004
    ....
  21. ncbi Minor gland and whole saliva in postmenopausal women using a low potency oestrogen (oestriol)
    L Eliasson
    Department of Cariology, Faculty of Odontology, Sahlgrenska Academy at Goteborg University, PO Box 450, SE 405 30 Goteborg, Sweden
    Arch Oral Biol 48:511-7. 2003
    ..Thus, the present findings indicate that a low dose oestrogen (oestriol) may affect the flow rate of labial salivary glands and the bacterial aggregation activity of whole saliva...
  22. ncbi Drug effects on salivary glands: dry mouth
    C Scully
    International Centres for Excellence in Dentistry and Department of Oral Medicine, Eastman Dental Institute for Oral Health Care Sciences, University of London, London, UK
    Oral Dis 9:165-76. 2003
    ..To identify drugs associated with the complaint of dry mouth...
  23. ncbi Characterization of muscarinic receptor binding and inhibition of salivation after oral administration of tolterodine in mice
    Tomomi Oki
    Department of Pharmacokinetics and Pharmacodynamics and COE Program in the 21st Century, School of Pharmaceutical Science, University of Shizuoka, Suruga ku, Shizuoka 422 8526, Japan
    Eur J Pharmacol 529:157-63. 2006
    ..oral administration of tolterodine on muscarinic receptor binding in the bladder and submaxillary gland and on salivation in mice...
  24. ncbi Age-related changes in unstimulated salivary function and composition and its relations to medications and oral sensorial complaints
    Rafael M Nagler
    Department of Oral and Maxillofacial Surgery, Oral Biochemistry Laboratory and Salivary Clinic, Rambam Medical Center and Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Aging Clin Exp Res 17:358-66. 2005
    ..OSC cover xerostomia, disturbed sense of taste, or burning mouth sensitivity with no established classical etiology (e.g., Sjogren's syndrome, or a response to radiotherapy)...
  25. ncbi Salivary secretion, taste and hyposalivation
    H Mese
    Department of Oral and Maxillofacial Surgery, and Biopathological Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    J Oral Rehabil 34:711-23. 2007
    ..This article reviews the mechanism of salivary secretion, effect of saliva on taste, importance of saliva in oral health, and hyposalivation in relation to ageing, medicine and/or disease and management of hyposalivation...
  26. ncbi Lesions of the lateral hypothalamus impair pilocarpine-induced salivation in rats
    A Renzi
    Department of Physiology and Pathology, School of Dentistry, Paulista State University, SP, Araraquara, Brazil
    Brain Res Bull 58:455-9. 2002
    In the present study we investigated the effects of electrolytic lesions of the lateral hypothalamus (LH) in the salivation induced by intracerebroventricular (i.c.v.) or intraperitoneal (i.p...
  27. ncbi Salivation pattern of Rhodnius prolixus (Reduviidae; Triatominae) in mouse skin
    Adriana Coelho Soares
    Departamento de Parasitologia, Instituto de Ciências Biológicas da Universidade Federal de Minas Gerais, Avenida Presidente Antonio Carlos, 6627, Campus Pampulha, Belo Horizonte, Minas Gerais, CEP 31270 901, Brazil
    J Insect Physiol 52:468-72. 2006
    The objective of this work was to study the pattern of salivation of triatomines during feeding in mouse skin. Rhodnius prolixus was fed with a solution of the dye acridine orange or fluorescein...
  28. pmc Muscarinic receptor binding, plasma concentration and inhibition of salivation after oral administration of a novel antimuscarinic agent, solifenacin succinate in mice
    Tomomi Oki
    Department of Biopharmaceutical Sciences, School of Pharmaceutical Sciences, University of Shizuoka, 52 1 Yada, Shizuoka 422 8526, Japan
    Br J Pharmacol 145:219-27. 2005
    ..It is concluded that oral solifenacin persistently binds to muscarinic receptors in tissues expressing the M(3) subtype, such as the bladder...
  29. ncbi The relation between saliva flow after different stimulations and the perception of flavor and texture attributes in custard desserts
    Lina Engelen
    Wageningen Centre for Food Sciences, 6700 AN, Wageningen, The Netherlands
    Physiol Behav 78:165-9. 2003
    ..This finding could indicate that subjects are used to their respective amounts of saliva to such a degree that the differences in sensory ratings between subjects cannot be explained by the interindividual difference in saliva flow rate...
  30. ncbi Aging and secretory reserve capacity of major salivary glands
    E M Ghezzi
    University of Michigan School of Dentistry, Department of Cariology, Restorative Sciences, and Endodontics, Ann Arbor, USA
    J Dent Res 82:844-8. 2003
    ..These findings suggest that salivary gland output is more adversely affected by an anti-sialogogue in healthy older vs. younger adults, supporting the secretory reserve hypothesis of salivary function...
  31. ncbi [A case with left mesial temporal lobe epilepsy characterized by abnormal massive salivation]
    M Morita
    Department of Neurology, Jikei University School of Medicine
    Rinsho Shinkeigaku 41:809-12. 2001
    ..Every seizure began with an upper abdominal discomfort, and often followed by massive salivation. Whenever the epileptic salivation happened, the patient lost consciousness, and sometimes she developed ..
  32. ncbi Salivation triggered by pilocarpine involves aquaporin-5 in normal rats but not in irradiated rats
    Tetsuya Asari
    Pharmacology Research Laboratory, Kissei Pharmaceutical Co Ltd, Azumino, Nagano, Japan
    Clin Exp Pharmacol Physiol 36:531-8. 2009
    ....
  33. ncbi Central alpha(2) adrenergic receptors and cholinergic-induced salivation in rats
    Ana Carolina Thomaz Takakura
    Department of Physiology and Pathology, School of Dentistry, Paulista State University, UNESP, Araraquara, SP, Brazil
    Brain Res Bull 59:383-6. 2003
    b>Salivation induced by intraperitoneal (i.p.) injections of pilocarpine (cholinergic agonist) is reduced by intracerebroventricular (i.c.v.) injections of moxonidine (alpha(2) adrenergic and imidazoline receptor agonist)...
  34. ncbi Possible role of nitric oxide in radiation-induced salivary gland dysfunction
    Ienaka Takeda
    Department of Oral Medicine, Tokyo Dental College, Chiba, Japan
    Radiat Res 159:465-70. 2003
    ..The finding that administration of an inhibitor of NO synthesis ameliorated the dysfunction of irradiated salivary glands indicates that NO plays a role as a mediator of the dry mouth symptoms that occur after irradiation...
  35. ncbi Modulation of salivation and heartburn in response to the site of acid infusion in the human oesophagus
    S K Dutta
    Department of Medicine, University of Maryland School of Medicine, Baltimore, USA
    Aliment Pharmacol Ther 32:795-800. 2010
    The pathogenesis of gastro-oesophageal reflux disease includes increased acid reflux, reduced salivation and impaired peristalsis. This may depend upon the height of acid wave and magnitude of oesophageal mucosal exposure...
  36. ncbi The role of age and salivation in acid clearance in symptomatic patients with gastro-oesophageal reflux disease
    W C Orr
    Lynn Institute for Health Care Research, Oklahoma City, OK 73112, USA
    Aliment Pharmacol Ther 15:1385-8. 2001
    ..CONCLUSIONS: Cholinergic stimulation of salivation is an effective means of facilitating oesophageal acid clearance...
  37. ncbi Application of umami taste stimulation to remedy hypogeusia based on reflex salivation
    Takashi Sasano
    Division of Oral Diagnosis and Radiology, Department of Oral Medicine and Surgery, Tohoku University Graduate School of Dentistry, 4 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    Biol Pharm Bull 33:1791-5. 2010
    ..Moreover, clinical studies have shown that treatment of hyposalivation diminishes hypogeusia, indicating that salivation is essential to maintain normal taste function...
  38. ncbi Oral medicine -- update for the dental practitioner: dry mouth and disorders of salivation
    C Scully
    Eastman Dental Institute for Oral Health Care Sciences, 256 Gray s Inn Road, UCL, University of London, London WC1X 8LD, UK
    Br Dent J 199:423-7. 2005
    ..Guidance on management and when to refer is also provided, along with relevant websites which offer further detail...
  39. ncbi Effects of sucking acidic candy on whole-mouth saliva composition
    T Jensdottir
    Department of Oral Medicine, School of Dentistry, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark
    Caries Res 39:468-74. 2005
    ..We conclude that sucking this type of acidic candies changes whole-mouth saliva composition so that it may have erosive potential and that high WSFR and WSbeta have protective effects against these salivary changes...
  40. ncbi Muscarinic receptors and salivary secretion
    Gordon B Proctor
    J Appl Physiol 100:1103-4. 2006
  41. ncbi Severe impairment of salivation in Na+/K+/2Cl- cotransporter (NKCC1)-deficient mice
    R L Evans
    Center for Oral Biology, Aab Institute of Biomedical Sciences and the Eastman Department of Dentistry, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Biol Chem 275:26720-6. 2000
    ..reduction (>60%) in the volume of saliva secreted in response to a muscarinic agonist, the primary in situ salivation signal...
  42. ncbi Investigations into the physiological role of muscarinic M2 and M4 muscarinic and M4 receptor subtypes using receptor knockout mice
    F P Bymaster
    Neuroscience Research Division, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285 0510, USA
    Life Sci 68:2473-9. 2001
    ..M2 and M4 muscarinic receptor knockout mice revealed that M2 receptors mediated tremor and hypothermia, but not salivation. The M4 receptors seem to play a modest role in salivation, but did not alter hypothermia and tremor...
  43. ncbi A simple test for salivary gland hypofunction using Oral Schirmer's test
    Pía López-Jornet
    Department of Oral Medicine, Faculty of Medicine and Dentistry, University of Murcia, Spain
    J Oral Pathol Med 35:244-8. 2006
    ..The objective of this study was to develop a test for detecting salivary gland hypofunction...
  44. ncbi [The role of saliva in maintaining oral health]
    P Defabianis
    Dipartimento di Odontostomatologia, Azienda Ospedaliera S Giovanni Battista di Torino, Universita degli Studi di Torino, Torino, Italy
    Minerva Stomatol 52:301-8. 2003
    ..The action of saliva and the multifunctional aspects of its components in both detrimental and beneficial effects on oral health are underlined...
  45. ncbi Effects of furosemide and bendroflumethiazide on saliva flow rate and composition
    T Nederfors
    Department of Dentistry, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
    Arch Oral Biol 49:507-13. 2004
    ....
  46. ncbi [Enduring oral dryness after acne treatment]
    C P Bots
    Afdeling Tandheelkundige Basiswetenschappen, Sectie Orale Biochemie van het Academisch Centrum Tandheelkunde Amsterdam ACTA
    Ned Tijdschr Tandheelkd 110:295-7. 2003
    ..It is suggested to register and monitor the use of medication in patients with sudden oral health changes...
  47. ncbi Sialochemical and gustatory analysis in patients with oral sensory complaints
    Rafael M Nagler
    Department of Oral and Maxillofacial Surtery, Oral Biochemistry Laboratory and Salivary Clinic, Rambam Medical Center, Haifa, Israel
    J Pain 5:56-63. 2004
    ..This report might add an important objective diagnostic tool to the clinician treating such patients...
  48. ncbi Evaluation of salivary gland function after treatment of head-and-neck tumors with intensity-modulated radiotherapy by quantitative pertechnetate scintigraphy
    Marc W Munter
    Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center DKFZ, Heidelberg, Germany
    Int J Radiat Oncol Biol Phys 58:175-84. 2004
    ..To evaluate salivary gland function after inversely planned stereotactic intensity-modulated radiotherapy (IMRT) for tumors of the head-and-neck region using quantitative pertechnetate scintigraphy...
  49. ncbi Dental plaque pH and micro-organisms during hyposalivation
    L Eliasson
    Department of Cariology, Faculty of Odontology, The Sahlgrenska Academy at Goteborg University, Box 450, SE 405 30 Goteborg, Sweden
    J Dent Res 85:334-8. 2006
    ..Stepwise regression tests suggested that the buccal minor-salivary-gland secretion rate in the test groups and counts of mutans streptococci in the controls were of significant importance for dental plaque pH...
  50. ncbi Decreased saliva secretion and down-regulation of AQP5 in submandibular gland in irradiated rats
    Zhimin Li
    Department of Oral Radiology, College of Stomatology, Jilin University, Changchun, China
    Radiat Res 165:678-87. 2006
    ..These results suggest that the preferential down-regulation of AQP5 with minor effects on AQP1 and Na(+)/K(+)-ATPase may contribute to radiation-induced salivary dysfunction...
  51. ncbi [Experimental and clinical investigations on the inhibition of secretion of the major salivary glands with botulinum toxin A]
    M Ellies
    HNO Klinik der Georg August Universität Göttingen
    Laryngorhinootologie 82:713-4. 2003
  52. ncbi Salivary gland function and xerostomia in southern Chinese following radiotherapy for nasopharyngeal carcinoma
    Edmond H N Pow
    Oral Rehabilitation, Faculty of Dentistry, University of Hong Kong, 34 Hospital Road, Hong Kong
    Clin Oral Investig 7:230-4. 2003
    ..In irradiated and non-irradiated southern Chinese, subjective dry mouth symptoms appeared to be correlated with actual salivary gland function...
  53. ncbi Saliva secretion and abnormal moistening of oral mucosa after bone marrow transplantation
    Agnieszka Bogusławska-Kapała
    Department of Conservative Dentistry, Medical University of Gdansk, Poland
    Bull Group Int Rech Sci Stomatol Odontol 47:1-5. 2006
    ..Those with normal moistening exhibited average rates of both stimulated and non-stimulated saliva secretion significantly higher than patients with abnormal moistening of oral mucosa...
  54. ncbi Evaluation of salivary flow in patients during head and neck radiotherapy
    Paulo Rogerio Ferreti Bonan
    School of Dentistry, University of Alfenas, USA
    Pesqui Odontol Bras 17:156-60. 2003
    ..0008), which continued low immediately after radiotherapy (p = 0.0009). Our study showed that radiotherapy leads to an important reduction of salivary flow during and after radiotherapy...
  55. ncbi Adjuvant chemotherapy in breast cancer patients induces temporary salivary gland hypofunction
    Siri Beier Jensen
    Department of Oral Medicine, Clinical Oral Physiology, Oral Pathology and Anatomy, Institute of Odontology, Faculty of Health Sciences, University of Copenhagen, Norre Alle 20, DK 2200 Copenhagen N, Denmark
    Oral Oncol 44:162-73. 2008
    ..Thus, the results suggest that acinar and ductal cell functions are affected by adjuvant CT. These adverse drug reactions are temporary, as salivary findings generally returned to baseline values within one year following treatment...
  56. pmc Progression of salivary gland dysfunction in patients with Sjogren's syndrome
    J Pijpe
    University Medical Center Groningen, University of Groningen, PO Box 30001, 9700 RB Groningen, The Netherlands
    Ann Rheum Dis 66:107-12. 2007
    ..Salivary gland dysfunction is one of the key manifestations of Sjögren's syndrome...
  57. ncbi Dramatic and prolonged decrease of whole salivary secretion in nasopharyngeal carcinoma patients treated with radiotherapy
    Yee Min Jen
    Department of Radiation Oncology, Tri Service General Hospital, Taipei, Taiwan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:322-7. 2006
    ....
  58. ncbi Xerostomia: a clinical approach
    David M Lewis
    Department of Oral and Maxillofacial Pathology, OUCOD
    J Okla Dent Assoc 97:22-5. 2005
  59. ncbi Does radiation dose to the salivary glands and oral cavity predict patient-rated xerostomia and sticky saliva in head and neck cancer patients treated with curative radiotherapy?
    Anke Petra Jellema
    Department of Radiation Oncology, VU University Medical Center, Amsterdam, The Netherlands
    Radiother Oncol 77:164-71. 2005
    ..To investigate the association between the mean salivary gland and oral cavity dose, with patient-rated moderate and severe xerostomia and sticky saliva...
  60. ncbi Effect of cevimeline on salivary components in patients with Sjögren syndrome
    Kimihiro Suzuki
    Internal Medicine I, National Defense Medical College, Tokorozawa, Japan
    Pharmacology 74:100-5. 2005
    ..It may be beneficial for SS patients to continue taking cevimeline to prevent oral infections, and other serious sequelae...
  61. ncbi Gland size estimation and body mass index improve salivary flow rate assessment
    C Dawes
    Department of Oral Biology, 780 Bannatyne Avenue, Winnipeg, Man R3E 0W2, Canada
    Arch Oral Biol 52:409-10. 2007
  62. ncbi Efficacy of the BioXtra dry mouth care system in the treatment of radiotherapy-induced xerostomia
    Piet Dirix
    Department of Radiation Oncology, Leuvens Kanker Instituut, University Hospital Gasthuisberg, Herestraat 49, 3000, Leuven, Belgium
    Support Care Cancer 15:1429-36. 2007
    ..Symptomatic treatment consists of stringent oral hygiene to prevent oral infections and saliva substitutes to increase comfort. The aim of the study was to evaluate the clinical effectiveness of the BioXtra (BX) dry mouth care system...
  63. ncbi Intensity-modulated radiation therapy and xerostomia
    Mark S Chambers
    Department of Head and Neck Surgery, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Calif Dent Assoc 34:743-8. 2006
    ....
  64. ncbi Opposite effects of antidepressants on unstimulated and stimulated salivary flow
    Luciane Kopittke
    Division of Pharmacology, Fundacao Faculdade Federal de Ciencias Medicas de Porto Alegre, Rua Sarmento Leite 245, 3rd Floor, 90050 170 Porto Alegre, RS, Brazil
    Arch Oral Biol 50:17-21. 2005
    ..The same opposite pattern of effects on non-stimulated and pilocarpine-stimulated salivation was seen after chronic treatment with the antidepressants...
  65. ncbi Relationships between age, drugs, oral sensorial complaints and salivary profile
    Rafael M Nagler
    Department of Oral and Maxillofacial Surgery, Oral Biochemistry Laboratory and Salivary Clinic, Rambam Medical Centre and Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Arch Oral Biol 50:7-16. 2005
    ....
  66. ncbi Pathophysiology and management of radiation-induced xerostomia
    Lawrence B Berk
    Newark Radiation Oncology, Newark, Ohio, USA
    J Support Oncol 3:191-200. 2005
    ..This article will review current knowledge concerning the anatomy and function of glands involved with salivation, measurement of salivary gland function, surgical and pharmacologic prevention and treatment of xerostomia, and ..
  67. pmc The impact of dose on parotid salivary recovery in head and neck cancer patients treated with radiation therapy
    Yun Li
    Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI 48109 2029, USA
    Int J Radiat Oncol Biol Phys 67:660-9. 2007
    ..Our purpose is to investigate the relationship between radiation dose and saliva changes in the 2 years after treatment...
  68. ncbi Salivary gland parameters and clinical data related to the underlying disorder in patients with persisting xerostomia
    Ianthe van den Berg
    Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur J Oral Sci 115:97-102. 2007
    ..Xerostomia-inducing medication was used by most patients. It was concluded that gland-specific sialometry and sialochemistry is useful in discriminating between the various disorders causing persisting xerostomia...
  69. ncbi Assessment of the use of sialogogues in the clinical management of patients with xerostomia
    Nita Chainani-Wu
    Department of Orofacial Sciences, University of California, San Francisco, Calif, USA
    Spec Care Dentist 26:164-70. 2006
    ..The observed carryover effect suggests that intermittent treatment may be an alternative to continuous treatment with sialogogues...
  70. ncbi Clinical and biochemical evaluation of the saliva of patients with xerostomia induced by radiotherapy
    Cássio de Barros Pontes
    Department of Physics and Chemistry, School of Pharmaceutical Sciences of Ribeirão Preto, University of Sao Paulo
    Braz Oral Res 18:69-74. 2004
    ..Clinically, patients presenting xerostomia induced by radiotherapy presented an increase in oral tissue injury...
  71. ncbi Gender difference in unstimulated whole saliva flow rate and salivary gland sizes
    H Inoue
    Department of Biosciences, Kyushu Dental College, 2 6 1 Manazuru, Kokurakitaku, Kitakyushu, Fukuoka 803 8580, Japan
    Arch Oral Biol 51:1055-60. 2006
    ..In this study, we investigated the relationships among the UWSFR, gland sizes and body sizes of healthy young adult males and females...
  72. ncbi [Usefulness of pilocarpine in the prevention of xerostomia in patients with head and neck cancer treated with radiotherapy. Assessment with gammagraphy and salivary flow]
    S Fuertes Cabero
    Servicio de Medicina Nuclear Hospital Clínic de Barcelona Universidad de Barcelona Spain
    Rev Esp Med Nucl 23:259-66. 2004
    ..To assess the utility of salivary gland scintigraphy and salivary flow to quantify salivary function and to evaluate the usefulness of pilocarpine in the treatment of radiation-induced xerestomia in head and neck cancer patients...
  73. ncbi Association between regional idiopathic neuropathy and salivary involvement as the possible mechanism for oral sensory complaints
    Michal Granot
    Faculty of Social Welfare and Health Studies, University of Haifa, Haifa, Israel
    J Pain 6:581-7. 2005
    ..Alternatively, a primary idiopathic salivary dysfunction might cause sensory neural dysfunction at the receptor level by changing the oral cavity milieu...
  74. ncbi Salivary enhancement therapies
    Philip C Fox
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Caries Res 38:241-6. 2004
    ..With improved secretagogues, the effects of conditions that result in reduced salivary function and increased caries will be ameliorated...
  75. ncbi The relationship between the levels of salivary cortisol and the presence of xerostomia in menopausal women. A preliminary study
    Begoña Rivera Gómez
    Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontologia, UCM, Madrid
    Med Oral Patol Oral Cir Bucal 11:E407-12. 2006
    ..Xerostomia is a particularly frequent occurrence among menopausal women, and is often associated with depression...
  76. ncbi Changes in salivary gland function after radiotherapy of head and neck tumors measured by quantitative pertechnetate scintigraphy: comparison of intensity-modulated radiotherapy and conventional radiation therapy with and without Amifostine
    Marc W Munter
    Department of Radiation Oncology, University of Heidelberg, Heidelberg, Germany
    Int J Radiat Oncol Biol Phys 67:651-9. 2007
    ....
  77. ncbi Effects of pilocarpine hydrochloride and cevimeline on submandibular/sublingual salivation in rat xerostomia model produced by X-ray irradiation
    Yasuhiro Omori
    Clinical Development, Kissei Pharmaceutical Co, Ltd, Hotaka, Nagano, Japan
    Arzneimittelforschung 53:342-50. 2003
    ..These results suggest that pilocarpine hydrochloride could be used as a sialagogic drug for postirradiation-induced xerostomia with fewer adverse effects on the CNS...
  78. ncbi The effects of duration and intensity of stimulation on total protein and mucin concentrations in resting and stimulated whole saliva
    S A Rayment
    Department of Periodontology and Oral Biology, Goldman School of Dental Medicine, Boston University School of Medicine, Boston University Medical Center, MA 02118, USA
    J Dent Res 80:1584-7. 2001
    ....
  79. ncbi Inadequate salivary flow and poor oral mucosal status in intubated intensive care unit patients
    Paul Dennesen
    Department of Medical Microbiology, University Hospital of Maastricht, The Netherlands
    Crit Care Med 31:781-6. 2003
    ..In addition, the pattern of oropharyngeal colonization was investigated in these patients...
  80. ncbi Effects of homeopathic treatment on salivary flow rate and subjective symptoms in patients with oral dryness: a randomized trial
    S Haila
    Porin Hammaspiste, Pori, Finland
    Homeopathy 94:175-81. 2005
    ..The symptoms of xerostomia improved in both groups. Our results suggest that individually prescribed homeopathic medicine could be a valuable adjunct to the treatment of oral discomfort and xerostomic symptoms...
  81. ncbi Effects of antidepressants and benzodiazepines on stimulated salivary flow rate and biochemistry composition of the saliva
    Patricia Del Vigna de Almeida
    Department of Stomatology, School of Dentistry, Pontificia Universidade Catolica do Parana, Curitiba, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106:58-65. 2008
    ....
  82. ncbi Saliva substitutes: how effective and safe are they?
    D Y D Samarawickrama
    Oral Dis 8:177-9. 2002
  83. ncbi Alterations of nitrate and nitrite content in saliva, serum, and urine in patients with salivary dysfunction
    Dengsheng Xia
    Salivary Gland Disease Center, Faculty of Stomatology, Capital University of Medical Sciences, Beijing, 00050, PR China
    J Oral Pathol Med 32:95-9. 2003
    ..The role of the salivary glands in the maintenance of nitrate and nitrite in saliva is poorly understood. The aim was to study alterations of nitrate and nitrite metabolisms in patients with Sjogren's syndrome (SS) or sialosis...
  84. ncbi Nizatidine enhances salivary secretion in patients with dry mouth
    T Nin
    Department of Otolaryngology, Hyogo College of Medicine, 1 1 Mukogawa, Nishinomiya City, Hyogo 663 8501, Japan
    Auris Nasus Larynx 35:224-9. 2008
    ..The aim of the present study was to investigate whether or not nizatidine enhances salivary secretion and improves the function of salivary glands in patients with dry mouth...
  85. ncbi Association of oral yeast carriage with specific host factors and altered mouth sensation
    Chika Shimizu
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:445-51. 2008
    ..The aim of this study was to determine if there was a significant association between the presence of altered mouth and taste sensations with oral carriage of yeasts and to assess the factors that influence the yeast carriage...
  86. ncbi Sialometrical and sialochemical analysis of patients with chronic graft-versus-host disease--a prolonged study
    R M Nagler
    Sheba Medical Center, Tel Hashamer, Israel
    Cancer Invest 21:34-40. 2003
    ....
  87. ncbi Salivary flow rates measured during radiation therapy in head and neck cancer patients: a pilot study assessing salivary sediment formation
    Mark S Chambers
    Department of Head and Neck Surgery, Department of Radiation Oncology, M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Prosthet Dent 100:142-6. 2008
    ..Determining the impact that salivary sediments have on measured salivary flow rates during radiation is important for management of patients...
  88. ncbi A new medication for treatment of dry mouth in Sjögren's syndrome
    I al-Hashimi
    Salivary Dysfunction Clinic, Department of Periodontics, Baylor College of Dentistry, TAMUS-HSC, Dallas, TX, USA
    Tex Dent J 118:262-6. 2001
    ..Both Salagen and Evoxac are FDA approved salivary stimulants. They are effective, and safe given awareness of their indications, contraindications, potential adverse effects, and patient's tolerance...
  89. ncbi Saliva: a fountain of opportunity
    Mahvash Navazesh
    Division of Diagnostic Sciences at University of Southern California School of Dentistry, 90089 0641, USA
    J Calif Dent Assoc 30:783-8. 2002
    ....
  90. ncbi Biochemical analysis of saliva and taste acuity evaluation in patients with burning mouth syndrome, xerostomia and/or gustatory disturbances
    Oded Hershkovich
    Oral Biochemistry Laboratory and Salivary Clinic, Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Rambam Medical Center, Technion Israel Institute of Technology, P O B 9602, Haifa 31096, Israel
    Arch Oral Biol 49:515-22. 2004
    ..In the current study, we performed taste and salivary analysis on patients suffering from burning mouth syndrome and xerostomia or taste disturbances...
  91. ncbi Effect of Pilocarpine on impaired salivary secretion in patients with Sjögren's syndrome
    Lars Jorkjend
    Section of Dental Pharmacology and Pharmacotherapy, University of Oslo, Norway
    Swed Dent J 32:49-56. 2008
    ..05), but not a RWS, rate at baseline. It is concluded that a subgroup of Sjögren patients do not respond to Pilocarpine stimulation. The clinical implications of this finding need further investigation...
  92. ncbi Submandibular and sublingual salivary gland function in familial dysautonomia
    Andy Wolff
    Hospital Dentistry Department, Assuta Hospital and Maccabi Health Services, Tel Aviv, Israel
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:315-9. 2002
    ..Drooling in familial dysautonomia (FD) has been attributed to denervation supersensitivity. The aim of this study was to investigate submandibular and sublingual (SM/SL) gland function in FD...
  93. ncbi In regards to Münter et Al. (Int J Radiat Oncol Biol Phys 2007;67:651-659)
    Michael A Samuels
    Int J Radiat Oncol Biol Phys 69:318; author reply 318-9. 2007
  94. ncbi Evaluation of some oral postradiotherapy sequelae in patients treated for head and neck tumors
    Cássia Maria Fischer Rubira
    Stomatology Department, School of Dentistry of Bauru, University of Sao Paulo, Brazil
    Braz Oral Res 21:272-7. 2007
    ..The main effect of radiotheraphy in the head and neck region was a reduction of the salivary flow rate, even though our study demonstrated that there was a modest late improvement of the salivary flow...
  95. ncbi Up-to-date report of botulinum toxin therapy in patients with drooling caused by different etiologies
    Maik Ellies
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Gottingen, Gottingen, Germany
    J Oral Maxillofac Surg 61:454-7. 2003
    ..We also present a controlled follow-up study documenting efficiency, possible adverse events, and duration of the effect of treatment...
  96. ncbi In regard to Münter et Al. Changes in salivary gland function after radiotherapy of head and neck tumors measured by quantitative pertechnetate scintigraphy: comparison of intensity-modulated radiotherapy and conventional radiation therapy with and withou
    Gerald L Messerschmidt
    Int J Radiat Oncol Biol Phys 69:1651-2; author reply 1652. 2007
  97. ncbi Lack of oncogenicity of wood creosote, the principal active ingredient of Seirogan, an herbal antidiarrheal medication, in Sprague-Dawley rats
    T Kuge
    Taiko Pharmaceutical Company, Ltd, Suita, Osaka, Japan
    Int J Toxicol 20:297-305. 2001
    ..food consumption, as well as increased incidences of clinical signs that included rales, decreased activity, and salivation, were noted at 200 mg/kg bw/day when compared with the control group...
  98. ncbi [Anxiolysis, sedation, and stress reduction following oral premedication with midazolam in adults. A comparison with dipotassium clorazepate and placebo]
    E Berendes
    Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Westfalische Wilhelms Universitat Munster
    Anaesthesist 45:506-11. 1996
    ..room, the following parameters were determined with visual analogue scales (VAS): "asthenia," "depression," oral salivation, muscle tension, motoric restlessness and sweating of the palms...
  99. ncbi Acute toxicity and cholinesterase inhibition in chicks dosed orally with organophosphate insecticides
    Fouad K Mohammad
    Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Mosul, Mosul, Iraq
    Arh Hig Rada Toksikol 59:145-51. 2008
    ..Signs of cholinergic toxicosis in the chicks appeared within two hours after dosing, and they included salivation, lacrimation, gasping, frequent defecation, drooping of wings, tremors, convulsions, and recumbency before death...
  100. ncbi Protection by a transdermal patch containing physostigmine and procyclidine of soman poisoning in dogs
    Wang Soo Kim
    Biomedical Section, Agency for Defense Development, Yuseong P O Box 35 1, Daejeon 305 600, Republic of Korea
    Eur J Pharmacol 525:135-42. 2005
    ..1 microg/kg, and high doses (> or = 1.4 LD50) of soman induced salivation, emesis, defecation and diarrhea, tremors and seizures, and recumbency of dogs, leading to 100% mortality in 24 ..
  101. ncbi Calcitonin gene-related peptide in rat salivary glands: neuronal localization, depletion upon nerve stimulation, and effects on salivation in relation to substance P
    J Ekstrom
    Department of Physiology, University of Lund, Sweden
    Neuroscience 26:933-49. 1988
    ..CGRP may interact positively with acetylcholine and certain nonclassical transmitters, and it may be involved (together with other neuropeptides) in the atropine-resistant parasympathetic secretion occurring in the glands under study...

Research Grants55

  1. Intranasal CNS delivery of drugs against organophosphorous threat agents
    ARYAN MANGALAM NAMBOODIRI; Fiscal Year: 2013
    ..of acetylcholine at synaptic and neuromuscular junctions leading to symptoms of acute CTA poisoning including salivation, lacrimation, defecation, muscular twitching, seizures/status epilepticus and ultimately rapid death due to ..
  2. PKC delta and cell renewal in irradiated taste epithelium
    MARY ELAINE REYLAND; Fiscal Year: 2012
    ..Plausible explanations have been put forth, including indirect effects, i.e., reduced salivation and oral blistering, and direct mechanisms such as disruption of taste bud innervation, loss of particular taste ..
  3. Effect of Baclofen on Alcohol Cue-Elicited Urges to Drink and Smoke
    GEORGE ANTHONY KENNA; Fiscal Year: 2011
    ..to the sight and smell of cues and psychophysiological responses (heart rate, mean arterial pressure and salivation changes) will also be assessed during the CR experiment...
  4. B Cell Expressed COX2 and AID Dependent Sjogrens Syndrome Autoimmunity
    PATRICIA K MONGINI; Fiscal Year: 2013
    ..disease characterized by salivary gland inflammation, AID-expressing B cells, pathogenic IgG autoAbs that impair salivation, and a high rate of B cell lymphoma...
  5. Improving Oral Health and Quality of Life After Oral Cancer: A Web-based Approach
    HODA J BADR; Fiscal Year: 2012
    ..provided by applicant): Survivors of oral cancers experience persistent sequelae, including abnormally reduced salivation or difficulty swallowing related to their disease and treatment...
  6. Adenosine Receptors and Restoration of Salivary Gland in Sjogren's Syndrome
    Umesh S Deshmukh; Fiscal Year: 2013
    ..treated with AR agonists and restoration of salivary gland function monitored by measuring pilocarpine induced salivation. Systemic immunosuppressive effects of AR agonists will be monitored by measuring autoantibody responses and ..
  7. NEURAL CONTROL OF TEMPERATURE REGULATION
    JACK BOULANT; Fiscal Year: 2006
    ..Responses include skin blood flow, evaporative heat loss (e.g., salivation/skin wetting, panting, sweating), shivering and non-shivering thermogenesis (via metabolic hormones and brown ..
  8. Habituation to food as a risk factor for pediatric obesity
    Leonard H Epstein; Fiscal Year: 2013
    ..in habituation over time (Specific Aim 3), to test the relationship between reflexive, physiological (salivation) and behavioral (responding for food) measures of habituation (Specific Aim 4), and assess whether relative ..
  9. Learning Theory to Improve Obesity Treatments
    Kerri N Boutelle; Fiscal Year: 2013
    ..We will evaluate pertinent outcomes related to overeating, including psychophysiological measurements of salivation and heart rate variability, self-reported cravings and a laboratory paradigm measuring overeating to determine ..
  10. HOST-REGULATED DEVELOPMENT IN ARTHROPOD VECTORS
    Dov Borovsky; Fiscal Year: 1993
    ..These include vitellogenesis, oogenesis, pheromone production, digestion, salivation, mating, sperm activation and development of pathogens...
  11. ALPHA-ADRENOCEPTOR SUBTYPE & CL CURRENT IN PAROTID ACINI
    CHARLES BOCKMAN; Fiscal Year: 2000
    ..Physiologic regulation of salivation results from release of norepinephrine from nerves supplying the parotid gland, which subsequently activates ..
  12. Utility of Muscarinic Agonists in Schizopherenia
    Edward McGuire; Fiscal Year: 2005
    ..function, and the lowest activity at M3 receptors, which mediate a variety of unwanted actions, including salivation and diarrhea...
  13. Ethnopharmacological Studies in Oral Medicine
    Michael Colvard; Fiscal Year: 2004
    ..extracted, the extracts tested in oral related affections, such as pain, inflammation, cancerous growth, and salivation. An Agreement will be set up between the University of Illinois at Chicago and the Universidad Latina of Costa ..
  14. Utility of Muscarinic Agonists for Alzheimer's disease
    DEBASIS GHOSH; Fiscal Year: 2002
    ..Alzheimer's disease have been based on compounds that mimic acetylcholine without producing side effects such as salivation or diarrhea...
  15. MECHANISMS OF ANION TRANSPORT IN SALIVARY GLANDS
    James E Melvin; Fiscal Year: 2010
    ..b>Salivation is a two step process...
  16. Mixture Modeling: Pesticide Drug Interactions
    Charles Timchalk; Fiscal Year: 2009
    ..It is fully anticipated that this approach will facilitate the understanding of a variety of complex chemical interactions as it relates to the occupational health implications of working with insecticides. ..
  17. Development of Selective Nanoporous Sorbents for Radionuclide Decorporation
    Charles Timchalk; Fiscal Year: 2008
    ..abstract_text> ..
  18. Saliva and Salivary Gland Function Research Conference
    JAMES MELVIN; Fiscal Year: 2008
    ..It is the goal of the organizing team to encourage both growth and enrichment of this important field and to stimulate new strategies for studying salivary glands. [unreadable] [unreadable] [unreadable]..
  19. The Future of Salivary Gland Research
    JAMES MELVIN; Fiscal Year: 2003
    ....
  20. 2005 Salivary Glands & Exocrine Secretion
    JAMES MELVIN; Fiscal Year: 2005
    ..It is the goal of the organizing team to encourage both growth and enrichment of this important field and to stimulate new strategies for studying salivary glands. ..
  21. INNOVATIVE BIOMONITORING FOR LEAD IN SALIVA
    Charles Timchalk; Fiscal Year: 2006
    ..It is reasonable to speculate that once this model system has been adequately validated it can readily be employed to screen sensitive populations (e.g. children) that are at greatest risk from chronic Pb exposure. ..
  22. Modifying the home T.V. watching environment
    Leonard Epstein; Fiscal Year: 2005
    ..abstract_text> ..
  23. Electroyte Transport in Small Airways
    Paul Quinton; Fiscal Year: 2009
    ..Correctly understanding this fundamental structure/function is critical to developing effective therapies. ..
  24. Affect Regulation Training for Alcoholics
    PAUL STASIEWICZ; Fiscal Year: 2009
    ..The long-term objective of this line of research is to make available to clinicians a brief, effective affect regulation intervention that can be added to enhance existing empirically-supported treatments for alcohol dependence. ..
  25. Blueprints for Transforming Research at UIC College of Dentistry
    Christine Wu; Fiscal Year: 2003
    ..With the systematic infrastructure improvement initiative, and through integration of interdisciplinary research and creation of critical mass, UIC COD will play a leading role in US academic dentistry. ..
  26. CONTEXTUAL CONTROL OF CRAVING FOR ALCOHOL
    PAUL STASIEWICZ; Fiscal Year: 2002
    ..abstract_text> ..
  27. Neural basis of learned food aversion and nausea
    CHARLES HORN; Fiscal Year: 2009
    ..Effective treatment of nausea may substantially improve the quality of life for patients with chronic disease. ..
  28. Brief Alcohol Intervention for School-to-Work Transitions
    Suzanne M Colby; Fiscal Year: 2010
    ..The proposed research would test the effects of BMI specifically in the under-studied and under-treated population of heavy drinking non-college young adults. ..
  29. Insecticide Action at the Local Anesthetic Receptor
    David M Soderlund; Fiscal Year: 2011
    ..This research will provide new insight into the structure of the local anesthetic receptor and its role in the neurotoxic actions of PTIs. ..
  30. GENETICS OF PARKINSON DISEASE IN THE AMISH
    Brad Racette; Fiscal Year: 2006
    ..abstract_text> ..
  31. Microbiology/Immunology of Periodontal Disease in T1DM
    Paul Moore; Fiscal Year: 2002
    ..An integrated multidisciplinary effort provides significant data collection capabilities essential for understanding the complex multifactorial etiology of periodontal disease in Type 1 diabetes. ..
  32. CONTROL OF FEEDING BEHAVIOR--HEPATIC AFFERENT SIGNALING
    CHARLES HORN; Fiscal Year: 2002
    ..Results from this project may contribute to a better understanding of metabolic stimuli that are sensed by the nervous system, and may elucidate neural controls that are involved in obesity, anorexia, and diabetes. ..
  33. GOLDENSEAL(HYDRASTIS CANADENSIS)REMEDY FOR ORAL DISEASES
    Christine Wu; Fiscal Year: 2002
    ..This application of CAM research will help to achieve better oral health and oral disease prevention, one of the to priority areas of focus specified b the U.S. Public Health Service in "Health People 2000." ..
  34. CL-/HCO3- EXCHANGE IN CYSTIC FIBROSIS SWEAT GLANDS
    Paul Quinton; Fiscal Year: 2001
    ..Defining HCO3 ion-transport and its relevance to CFTR function should lend much to explaining, and hopefully, ameliorating these problems. ..
  35. Habituation to food in children
    Leonard Epstein; Fiscal Year: 2009
    ..These studies are designed to understand how individual differences in habituation may be an important factor that differentiates overweight and non-overweight youth. ..
  36. Food reinforcement-genotype interactions and eating
    Leonard H Epstein; Fiscal Year: 2010
    ..The findings are relevant to a greater understanding of behavioral and genetic factors related to obesity, as well as providing ideas that may be relevant for treatment interventions for those high in food reinforcement. ..
  37. Obesity as a Risk Factor for Adolescent Psychopathology
    Kerri Boutelle; Fiscal Year: 2005
    ..The overall purpose of these analyses is to evaluate the weight-related etiological risk factors for psychopathology, and to identify intervention opportunities to prevent the development of psychopathology in adolescents. ..
  38. A BEHAVIORAL ECONOMIC APPROACH TO CHILDHOOD OBESITY
    Leonard Epstein; Fiscal Year: 2005
    ..This study will yield important information on new ways to treat pediatric obesity, minimizing dietary restriction and maximizing children learning healthier eating habits. ..
  39. Contingency Management and MET for Adolescent Smoking
    PETER MONTI; Fiscal Year: 2006
    ..By integrating two behavioral interventions, this work has the potential to reduce smoking rates among heavier smoking adolescents and enhance our understanding of mechanisms of action. ..
  40. Improving Generalizability of Extinction to Alcohol Cues
    James MacKillop; Fiscal Year: 2004
    ..This study attempts to extend this latter finding to a human population and evaluate whether multiple context exposure will enhance extinction to alcohol cues, toward ultimately enhancing CET for alcohol dependence. ..
  41. Smoking Versus Alternative Reinforcers in Adolescents
    Suzanne Colby; Fiscal Year: 2007
    ..Study findings will advance our understanding of reinforcement mechanisms underlying adolescent smoking, which could also have implications for understanding and treating adolescent drug use more generally. ..
  42. EFFECTS OF CHANGING SEDENTARY BEHAVIOR IN OBESE CHILDREN
    Leonard Epstein; Fiscal Year: 2008
    ..Developing a better understanding of why obese youth increase physical activity or decrease energy intake when sedentary behaviors are reduced is important for the treatment of pediatric obesity. [unreadable] [unreadable] [unreadable]..
  43. Salivary Stem Cell Identification for Tissue Restoration
    Chih ko Yeh; Fiscal Year: 2004
    ..The results of these studies will ultimately lead to revolutionary treatment of salivary gland diseases. ..
  44. Emotional Processing as a Change Mechanism in Alcohol Treatment
    PAUL STASIEWICZ; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  45. World Workshop in Oral Medicine IV
    Peter Lockhart; Fiscal Year: 2005
    ..The proceedings will be published as evidence-based recommendations for best clinical practice in Oral Medicine as well as providing suggestions for future basic science and clinical research. ..
  46. Bacteremia from Dental Extraction vs. Oral Hygiene
    Peter Lockhart; Fiscal Year: 2004
    ..Additionally, we will have unique and critical data for the development of both future research and evidence-based guidelines concerning antibiotic prophylaxis for individuals currently felt to be at risk for DSI. ..
  47. ORAL HEALTH OF OLDER TYPE 1 DIABETIC PATIENTS
    Paul Moore; Fiscal Year: 2003
    ..This overall plan will permit us to understand the etiology of these complications and to define specific subpopulations and risk factors appropriate for future prospective oral health prevention and intervention trials. ..
  48. Epidemilogy of Parkinsonism in Welders
    Brad A Racette; Fiscal Year: 2011
    ..The cohort assembled will provide unique opportunities for future research projects into gene-environment interactions and exposure related neuroimaging changes. ..
  49. Supplementing Relaxation & Music for Postoperative Pain
    Marion Good; Fiscal Year: 2004
    ..Knowledge of the effects of patient teaching and non-invasive methods to reduce post-operative pain, stress, and immune function may facilitate postoperative recovery with lower health-care cost. ..
  50. Oral Health Outcomes of Early Childhood Malnutrition
    Walter Psoter; Fiscal Year: 2006
    ..Given the universality of PEM pathophysiology, this study's findings will be generalizable to subsets of U.S. children having 9 oral health disparities. [unreadable] [unreadable]..
  51. MEASURING DEPENDENCE AND WITHDRAWAL IN TEEN SMOKERS
    Suzanne Colby; Fiscal Year: 2001
    ..Thus, it will provide a greater understanding of nicotine withdrawal as a maintaining factor of adolescent smoking, and thereby provide an empirical basis for enhancing smoking cessation approaches for youth. ..
  52. Stress and Subsequent Drinking in Individuals with Different Drinking Motives
    Suzanne Thomas; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..