body composition


Summary: The relative amounts of various components in the body, such as percent body fat.

Top Publications

  1. pmc Gender differences in insulin resistance, body composition, and energy balance
    Eliza B Geer
    Division of Endocrinology, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Gend Med 6:60-75. 2009
  2. pmc Comparisons of percentage body fat, body mass index, waist circumference, and waist-stature ratio in adults
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    Am J Clin Nutr 89:500-8. 2009
  3. ncbi Sexual dimorphism of body composition
    Jonathan C K Wells
    Pediatric Nutrition Childhood Nutrition Research Centre, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Best Pract Res Clin Endocrinol Metab 21:415-30. 2007
  4. pmc The environment within: how gut microbiota may influence metabolism and body composition
    A Vrieze
    Department of Internal and Vascular Medicine, Academic Medical Centre, Meibergdreef 9, Room F4 159 2, 1105, AZ Amsterdam, The Netherlands
    Diabetologia 53:606-13. 2010
  5. pmc Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
    Elisa Fabbrini
    Center for Human Nutrition and Atkins Center of Excellence in Obesity Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 106:15430-5. 2009
  6. ncbi Obesity in children and young people: a crisis in public health
    T Lobstein
    IASO International Obesity TaskForce, 231 North Gower Street, London NW1 2NS, UK
    Obes Rev 5:4-104. 2004
  7. pmc High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition
    Morten M Poulsen
    Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
    Diabetes 62:1186-95. 2013
  8. pmc Maternal and child undernutrition: consequences for adult health and human capital
    Cesar G Victora
    Universidade Federal de Pelotas, Pelotas, Brazil
    Lancet 371:340-57. 2008
  9. pmc Genome-wide association study identifies Loci for body composition and structural soundness traits in pigs
    Bin Fan
    Department of Animal Science and Center for Integrated Animal Genomics, Iowa State University, Ames, Iowa, United States of America
    PLoS ONE 6:e14726. 2011
  10. ncbi Effects of active video games on body composition: a randomized controlled trial
    Ralph Maddison
    Clinical Trials Research Unit, University of Auckland, Auckland, New Zealand
    Am J Clin Nutr 94:156-63. 2011

Detail Information

Publications363 found, 100 shown here

  1. pmc Gender differences in insulin resistance, body composition, and energy balance
    Eliza B Geer
    Division of Endocrinology, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Gend Med 6:60-75. 2009
    Men and women differ substantially in regard to degrees of insulin resistance, body composition, and energy balance...
  2. pmc Comparisons of percentage body fat, body mass index, waist circumference, and waist-stature ratio in adults
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    Am J Clin Nutr 89:500-8. 2009
    ..Body mass index (BMI), waist circumference (WC), and the waist-stature ratio (WSR) are considered to be possible proxies for adiposity...
  3. ncbi Sexual dimorphism of body composition
    Jonathan C K Wells
    Pediatric Nutrition Childhood Nutrition Research Centre, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Best Pract Res Clin Endocrinol Metab 21:415-30. 2007
    Sexual dimorphism in human body composition is evident from fetal life, but emerges primarily during puberty. At birth, males have a similar fat mass to females but are longer and have greater lean mass...
  4. pmc The environment within: how gut microbiota may influence metabolism and body composition
    A Vrieze
    Department of Internal and Vascular Medicine, Academic Medical Centre, Meibergdreef 9, Room F4 159 2, 1105, AZ Amsterdam, The Netherlands
    Diabetologia 53:606-13. 2010
    ..This review discusses the relationships between the following: composition of gut microbiota, energy extracted from diet, synthesis of gut hormones involved in energy homeostasis, production of butyrate and the regulation of fat storage...
  5. pmc Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
    Elisa Fabbrini
    Center for Human Nutrition and Atkins Center of Excellence in Obesity Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 106:15430-5. 2009
    ..Furthermore, alterations in tissue fatty acid transport could be involved in the pathogenesis of ectopic triglyceride accumulation by redirecting plasma fatty acid uptake from adipose tissue toward other tissues...
  6. ncbi Obesity in children and young people: a crisis in public health
    T Lobstein
    IASO International Obesity TaskForce, 231 North Gower Street, London NW1 2NS, UK
    Obes Rev 5:4-104. 2004
  7. pmc High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition
    Morten M Poulsen
    Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
    Diabetes 62:1186-95. 2013
    ..The lack of effect disagrees with persuasive data obtained from rodent models and raises doubt about the justification of resveratrol as a human nutritional supplement in metabolic disorders...
  8. pmc Maternal and child undernutrition: consequences for adult health and human capital
    Cesar G Victora
    Universidade Federal de Pelotas, Pelotas, Brazil
    Lancet 371:340-57. 2008
    ..Its prevention will probably bring about important health, educational, and economic benefits. Chronic diseases are especially common in undernourished children who experience rapid weight gain after infancy...
  9. pmc Genome-wide association study identifies Loci for body composition and structural soundness traits in pigs
    Bin Fan
    Department of Animal Science and Center for Integrated Animal Genomics, Iowa State University, Ames, Iowa, United States of America
    PLoS ONE 6:e14726. 2011
    ..The recent completion of the swine genome sequencing project and development of a high density porcine SNP array has made genome-wide association (GWA) studies feasible in pigs...
  10. ncbi Effects of active video games on body composition: a randomized controlled trial
    Ralph Maddison
    Clinical Trials Research Unit, University of Auckland, Auckland, New Zealand
    Am J Clin Nutr 94:156-63. 2011
    Sedentary activities such as video gaming are independently associated with obesity. Active video games, in which players physically interact with images on screen, may help increase physical activity and improve body composition.
  11. ncbi Asians are different from Caucasians and from each other in their body mass index/body fat per cent relationship
    P Deurenberg
    Wageningen University, The Netherlands
    Obes Rev 3:141-6. 2002
    ..Hence, the relationship between BF% and BMI is ethnic-specific. For comparisons of obesity prevalence between ethnic groups, universal BMI cut-off points are not appropriate...
  12. ncbi Body composition, visceral fat, leptin, and insulin resistance in Asian Indian men
    M A Banerji
    Department of Medicine, State University of New York Health Science Center, Brooklyn 11203, USA
    J Clin Endocrinol Metab 84:137-44. 1999
    ..Increased visceral fat is related to dyslipidemia and increased frequency of insulin resistance and may account for the increased prevalence of diabetes mellitus and cardiovascular disease in Asian Indians...
  13. pmc Adult onset global loss of the fto gene alters body composition and metabolism in the mouse
    Fiona McMurray
    MRC Harwell, Harwell Science and Innovation Campus, Harwell, United Kingdom
    PLoS Genet 9:e1003166. 2013
    ..Rodent studies demonstrate a role for FTO in energy homeostasis and body composition. The phenotypes observed in loss of expression studies are complex with perinatal lethality, stunted growth ..
  14. pmc Effect of diet and exercise, alone or combined, on weight and body composition in overweight-to-obese postmenopausal women
    Karen E Foster-Schubert
    Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Obesity (Silver Spring) 20:1628-38. 2012
    ..Among postmenopausal women, lifestyle-change involving diet, exercise, or both combined over 1 year improves body weight and adiposity, with the greatest change arising from the combined intervention...
  15. ncbi Waist circumference and waist-to-height ratio are better predictors of cardiovascular disease risk factors in children than body mass index
    S C Savva
    Research and Education Program of Child Health, Cyprus
    Int J Obes Relat Metab Disord 24:1453-8. 2000
    ..Waist measurement and waist-to-height ratio (WHtR) have been used as proxy measures of visceral adipose tissue, mainly in adults...
  16. ncbi Bioelectrical impedance analysis--part I: review of principles and methods
    Ursula G Kyle
    Geneva University Hospital, Switzerland
    Clin Nutr 23:1226-43. 2004
    ..ESPEN guidelines for the clinical use of BIA measurements are described in a paper to appear soon in Clinical Nutrition...
  17. ncbi Subcutaneous and visceral adipose tissue: structural and functional differences
    M Mohsen Ibrahim
    Cardiology Department, Cairo University, 1 El Sherifein Street, Abdeen, Cairo 11111, Egypt
    Obes Rev 11:11-8. 2010
    ..VAT carries a greater prediction of mortality than SCAT...
  18. pmc Accuracy of body mass index in diagnosing obesity in the adult general population
    A Romero-Corral
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, MN 55905, USA
    Int J Obes (Lond) 32:959-66. 2008
    ..Body mass index (BMI) is the most widely used measure to diagnose obesity. However, the accuracy of BMI in detecting excess body adiposity in the adult general population is largely unknown...
  19. ncbi A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig
    Anne Sophie Van Laere
    Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala University, BMC, Box 597, SE 751 24 Uppsala, Sweden
    Nature 425:832-6. 2003
    ..The result supports the long-held view that regulatory mutations are important for controlling phenotypic variation...
  20. ncbi Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled study
    Upendram Srinivas-Shankar
    Andrology Research Unit, Department of Medicine and Endocrinology, University of Manchester, Manchester Royal Infirmary, Grafton Street, Manchester, United Kingdom M13 9WL
    J Clin Endocrinol Metab 95:639-50. 2010
    ..Testosterone (T) increases muscle mass and strength in hypogonadal patients. It is unclear whether T has similar effects in intermediate-frail and frail elderly men with low to borderline-low T...
  21. ncbi What aspects of body fat are particularly hazardous and how do we measure them?
    M B Snijder
    Institute of Health Sciences, Faculty of Earth and Life Sciences, Vrije Universiteit Amsterdam, The Netherlands
    Int J Epidemiol 35:83-92. 2006
  22. ncbi Visceral adipose tissue accumulation differs according to ethnic background: results of the Multicultural Community Health Assessment Trial (M-CHAT)
    Scott A Lear
    School of Kinesiology, Simon Fraser University, Vancouver, BC, Canada
    Am J Clin Nutr 86:353-9. 2007
    ..Previous studies have not adequately investigated differences in discrete regions of abdominal adiposity across ethnic groups...
  23. ncbi Beyond body mass index
    A M Prentice
    MRC International Nutrition Group, Public Health Nutrition Unit, London School of Hygiene and Tropical Medicine, 49 51 Bedford Square, London, WC1B 3DP, UK
    Obes Rev 2:141-7. 2001
    ..We argue that BMI continues to serve well for many purposes, but that the time is now right to initiate a gradual evolution beyond BMI towards standards based on actual measurements of body fat mass...
  24. ncbi Sarcopenia: alternative definitions and associations with lower extremity function
    Anne B Newman
    Division of Geriatric Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Geriatr Soc 51:1602-9. 2003
    ..two sarcopenia definitions and examine the relationship between them and lower extremity function and other health related factors using data from the baseline examination of the Health Aging and Body Composition (Health ABC) Study.
  25. ncbi Bioelectrical impedance analysis-part II: utilization in clinical practice
    Ursula G Kyle
    Clinical Nutrition Unit, Geneva University Hospital, 1211 Geneva 14, Switzerland
    Clin Nutr 23:1430-53. 2004
    ..Longitudinal follow-up of body composition by BIA is possible in subjects with BMI 16-34 kg/m(2) without abnormal hydration, but must be interpreted ..
  26. ncbi The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study
    Bret H Goodpaster
    Department of Medicine, MUH N809, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Gerontol A Biol Sci Med Sci 61:1059-64. 2006
    ..The loss of muscle mass is considered to be a major determinant of strength loss in aging. However, large-scale longitudinal studies examining the association between the loss of mass and strength in older adults are lacking...
  27. ncbi Variation in FTO contributes to childhood obesity and severe adult obesity
    Christian Dina
    CNRS 8090 Institute of Biology, Pasteur Institute, Lille, France
    Nat Genet 39:724-6. 2007
    ..The at-risk haplotype yields a proportion of attributable risk of 22% for common obesity. We conclude that FTO contributes to human obesity and hence may be a target for subsequent functional analyses...
  28. ncbi Percentage of body fat cutoffs by sex, age, and race-ethnicity in the US adult population from NHANES 1999-2004
    Moonseong Heo
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Am J Clin Nutr 95:594-602. 2012
    ..To date, there is no consensus regarding adult cutoffs of percentage of body fat or estimated cutoffs on the basis of nationally representative samples with rigorous body-composition measurements...
  29. pmc Associations of birth order with early growth and adolescent height, body composition, and blood pressure: prospective birth cohort from Brazil
    Jonathan C K Wells
    Childhood Nutrition Research Centre, Institute of Child Health, University College London, United Kingdom
    Am J Epidemiol 174:1028-35. 2011
    ..was to investigate differences between firstborn and later-born individuals in early growth patterns, body composition, and blood pressure in Brazilian adolescents. The authors studied 453 adolescents aged 13...
  30. pmc Relationship of obesity with osteoporosis
    Lan Juan Zhao
    Department of Orthopedic Surgery, School of Medicine, University of Missouri Kansas City, 2411 Holmes Street, Kansas City, MO 64108, USA
    J Clin Endocrinol Metab 92:1640-6. 2007
    ..Previous analyses, however, did not control for the mechanical loading effects of total body weight on bone mass and may have generated a confounded or even biased relationship between obesity and osteoporosis...
  31. ncbi Weight-reducing effects of the plasma protein encoded by the obese gene
    J L Halaas
    Laboratory of Molecular Genetics, Howard Hughes Medical Institute, Rockfeller University, New York, NY 10021, USA
    Science 269:543-6. 1995
    ..2 to 0.7 percent. These data suggest that the OB protein serves an endocrine function to regulate body fat stores...
  32. ncbi Body composition and mortality in chronic obstructive pulmonary disease
    Annemie M W J Schols
    Department of Respiratory Medicine, University of Maastricht, Maastricht, Netherlands
    Am J Clin Nutr 82:53-9. 2005
    ..Survival studies have consistently shown significantly greater mortality rates in underweight and normal-weight patients with chronic obstructive pulmonary disease (COPD) than in overweight and obese COPD patients...
  33. ncbi Attenuation of skeletal muscle and strength in the elderly: The Health ABC Study
    B H Goodpaster
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Appl Physiol (1985) 90:2157-65. 2001
    ..yr participating in baseline studies of the Health ABC Study, a longitudinal study of health, aging, and body composition. Strength was higher in men than in women (132.3 +/- 34.5 vs. 81.4 +/- 22.0 N x m, P < 0.01)...
  34. ncbi Development of bioelectrical impedance analysis prediction equations for body composition with the use of a multicomponent model for use in epidemiologic surveys
    Shumei S Sun
    Lifespan Research Center, Department of Community Health, Wright State University School of Medicine, Dayton, OH 45420, USA
    Am J Clin Nutr 77:331-40. 2003
    Previous studies to develop and validate bioelectrical impedance analysis (BIA) equations to predict body composition were limited by small sample sizes, sex specificity, and reliance on reference methods that use a 2-component model.
  35. ncbi Fetal programming and adult health
    K M Godfrey
    MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, UK
    Public Health Nutr 4:611-24. 2001
    ..Although the influences that impair fetal development and programme adult cardiovascular disease remain to be defined, there are strong pointers to the importance of maternal body composition and dietary balance during pregnancy.
  36. ncbi Total-body skeletal muscle mass: estimation by a new dual-energy X-ray absorptiometry method
    Jaehee Kim
    Obesity Research Center, St Luke s Roosevelt Hospital and the Institute of Human Nutrition, Columbia University, College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Clin Nutr 76:378-83. 2002
    ..A large proportion of total-body SM is found in the extremities, and a large proportion of extremity lean soft tissue is SM. A strong link should thus exist between appendicular lean soft tissue (ALST) mass and total-body SM mass...
  37. pmc Metformin in gestational diabetes: the offspring follow-up (MiG TOFU): body composition at 2 years of age
    Janet A Rowan
    Department of Obstetrics, National Women s Health, Auckland, New Zealand
    Diabetes Care 34:2279-84. 2011
    ..Metformin crosses the placenta, so it is important to assess potential effects on growth of the children...
  38. ncbi Body composition of a young, multiethnic, male population
    K J Ellis
    US Department of Agriculture, Agricultural Research Service, Children s Nutrition Research Center, Houston, TX 77030 2600, USA
    Am J Clin Nutr 66:1323-31. 1997
    ..Ethnic-specific equations for the prediction of body composition as a function of age, weight, and height were derived...
  39. pmc Dual energy X-Ray absorptiometry body composition reference values from NHANES
    Thomas L Kelly
    Hologic, Inc, Bedford, Massachusetts, USA
    PLoS ONE 4:e7038. 2009
  40. ncbi Effects of a multidisciplinary inpatient intervention on body composition, aerobic fitness, and quality of life in severely obese girls and boys
    Bruno H KnOpfli
    Alpine Children s Hospital Davos, Switzerland
    J Adolesc Health 42:119-27. 2008
    ..The aim of this study was to evaluate the gender differences of an 8-week multidisciplinary inpatient program on body weight, body composition, aerobic fitness, and quality of life of severely obese children and adolescents.
  41. ncbi Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons
    Marjolein Visser
    Institute for Research in Extramural Medicine, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    J Gerontol A Biol Sci Med Sci 60:324-33. 2005
    ..This study aims to investigate whether low muscle mass, low muscle strength, and greater fat infiltration into the muscle predict incident mobility limitation...
  42. pmc Effect of exercise training intensity on abdominal visceral fat and body composition
    Brian A Irving
    Department of Human Services, Division of Endocrinology and Metabolism, University of Virginia, Charlottesville, VA, USA
    Med Sci Sports Exerc 40:1863-72. 2008
    ..The metabolic syndrome is a complex clustering of metabolic defects associated with physical inactivity, abdominal adiposity, and aging...
  43. ncbi Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons
    Pablo J Enriori
    Division of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97006, USA
    Cell Metab 5:181-94. 2007
    ..These results highlight the physiological importance of leptin sensing in the melanocortin circuits and show that their loss of leptin sensing likely contributes to the pathology of leptin resistance...
  44. ncbi The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity
    Roberto Coppari
    Department of Medicine, Division of Endocrinology, Beth Israel Deaconess Medical Center, Harvard Medical School, 99 Brookline Avenue, Boston, Massachusetts 02215, USA
    Cell Metab 1:63-72. 2005
    ..These data demonstrate that leptin signaling in the ARH is sufficient for mediating leptin's effects on glucose homeostasis and locomotor activity...
  45. ncbi Infant growth and later body composition: evidence from the 4-component model
    Sirinuch Chomtho
    The Medical Research Council, Childhood Nutrition Research Centre, Institute of Child Health, University College London, London, United Kingdom
    Am J Clin Nutr 87:1776-84. 2008
    ..Rapid weight gain in infancy is associated with higher body mass index in later life, but its relation with individual body-composition components remains unclear...
  46. ncbi Body composition in healthy aging
    R N Baumgartner
    Division of Epidemiology and Preventive Medicine, University of New Mexico School of Medicine, Albuquerque 87131, USA
    Ann N Y Acad Sci 904:437-48. 2000
    ..These nonfat components of body composition play critical roles, influencing cognitive and physical functional status, nutritional and endocrine status, ..
  47. ncbi Comparison of 4 diets of varying glycemic load on weight loss and cardiovascular risk reduction in overweight and obese young adults: a randomized controlled trial
    Joanna McMillan-Price
    Human Nutrition Unit, University of Sydney, Sydney, Australia
    Arch Intern Med 166:1466-75. 2006
    ..Despite the popularity of low-glycemic index (GI) and high-protein diets, to our knowledge no randomized, controlled trials have systematically compared their relative effects on weight loss and cardiovascular risk...
  48. ncbi Metabolic and body composition factors in subgroups of obesity: what do we know?
    Antony D Karelis
    Departement de Nutrition, Unité métabolique, Universite de Montreal, Montreal, Quebec, Canada H3T 1A8
    J Clin Endocrinol Metab 89:2569-75. 2004
    ..The purpose of this review was to investigate the roles of metabolic, body composition, and cardiovascular disease risk in subtypes of obesity...
  49. ncbi Vitamin D(3) is more potent than vitamin D(2) in humans
    Robert P Heaney
    Creighton University, 601 North 30th Street, Suite 4841, Omaha, Nebraska 68131, USA
    J Clin Endocrinol Metab 96:E447-52. 2011
    ..Current unitage for the calciferols suggests that equimolar quantities of vitamins D(2) (D2) and D(3) (D3) are biologically equivalent. Published studies yield mixed results...
  50. ncbi Outdoor temperature, age, sex, body mass index, and diabetic status determine the prevalence, mass, and glucose-uptake activity of 18F-FDG-detected BAT in humans
    Veronique Ouellet
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Faculty of Medicine, Universite Laval, Quebec, Quebec, Canada
    J Clin Endocrinol Metab 96:192-9. 2011
  51. ncbi Obesity, regional body fat distribution, and the metabolic syndrome in older men and women
    Bret H Goodpaster
    Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Arch Intern Med 165:777-83. 2005
    ..We determined whether patterns of regional fat deposition are associated with metabolic syndrome in older adults...
  52. pmc Objectively measured physical activity and fat mass in a large cohort of children
    Andy R Ness
    Department of Oral and Dental Science, University of Bristol, United Kingdom
    PLoS Med 4:e97. 2007
    ..Previous studies have been unable to characterise the association between physical activity and obesity, possibly because most relied on inaccurate measures of physical activity and obesity...
  53. ncbi Neonatal anthropometry: the thin-fat Indian baby. The Pune Maternal Nutrition Study
    C S Yajnik
    King Edward Memorial Hospital, Rasta Peth, Pune, India
    Int J Obes Relat Metab Disord 27:173-80. 2003
    ..To examine body size and fat measurements of babies born in rural India and compare them with white Caucasian babies born in an industrialised country...
  54. ncbi Contributions of total body fat, abdominal subcutaneous adipose tissue compartments, and visceral adipose tissue to the metabolic complications of obesity
    S R Smith
    Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Metabolism 50:425-35. 2001
    ..375). These data suggest that total body fat is a major contributor to the metabolic sequelae of obesity, with specific fat depots, VAT, and DSAT also making significant contributions...
  55. ncbi Body fluid volume determination via body composition spectroscopy in health and disease
    Ulrich M Moissl
    Fresenius Medical Care Deutschland GmbH, Research and Development, Daimlerstrasse 15, D 61352 Bad Homburg, Germany
    Physiol Meas 27:921-33. 2006
    ..terms of usability and reproducibility, but a careful analysis reveals systematic deviations in extremes of body composition and morbid states...
  56. pmc Measuring body composition
    J C K Wells
    MRC Childhood Nutrition Centre, Institute of Child Health, London WC1, UK
    Arch Dis Child 91:612-7. 2006
    Several aspects of body composition, in particular the amount and distribution of body fat and the amount and composition of lean mass, are now understood to be important health outcomes in infants and children...
  57. ncbi Programming of body composition by early growth and nutrition
    Jonathan C K Wells
    Childhood Nutrition Research Centre, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Proc Nutr Soc 66:423-34. 2007
    ..postnatal growth for such associations remains controversial. Body composition may play a key role in the 'programming' of such diseases, through itself being programmed by early growth, ..
  58. ncbi Effects of the amount of exercise on body weight, body composition, and measures of central obesity: STRRIDE--a randomized controlled study
    Cris A Slentz
    Divisions of Cardiology, Geriatric Medicine, and General Internal Medicine, Department of Medicine, Duke Center for Living, Center for Health Policy Research, Durham, NC 27710, USA
    Arch Intern Med 164:31-9. 2004
    ..Obesity is a major health problem due, in part, to physical inactivity. The amount of activity needed to prevent weight gain is unknown...
  59. ncbi Decreased muscle strength and quality in older adults with type 2 diabetes: the health, aging, and body composition study
    Seok Won Park
    Department of Internal Medicine, Pochon CHA University, Pochon, Korea
    Diabetes 55:1813-8. 2006
    ..and muscle mass in 485 older adults with diabetes and 2,133 without diabetes in the Health, Aging, and Body Composition study...
  60. ncbi Visceral fat is an independent predictor of all-cause mortality in men
    Jennifer L Kuk
    School of Physical and Health Education, Queen s University, Kingston, Ontario K7L 3N6, Canada
    Obesity (Silver Spring) 14:336-41. 2006
    ..To examine the independent associations of abdominal fat (visceral and subcutaneous) and liver fat with all-cause mortality...
  61. pmc Physical activity intensity, sedentary time, and body composition in preschoolers
    Paul J Collings
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 97:1020-8. 2013
    Detailed associations between physical activity (PA) subcomponents, sedentary time, and body composition in preschoolers remain unclear.
  62. ncbi Inflammatory markers and depressed mood in older persons: results from the Health, Aging and Body Composition study
    Brenda W J H Penninx
    Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Biol Psychiatry 54:566-72. 2003
    ..Data are from 3024 well-functioning older persons, 70-79 years of age, participating in the Health, Aging and Body Composition study...
  63. pmc Differences in body composition between infants of South Asian and European ancestry: the London Mother and Baby Study
    Kristina M Stanfield
    London School of Hygiene and Tropical Medicine, London, UK
    Int J Epidemiol 41:1409-18. 2012
    South Asian children and adults have a more adipose body composition compared with those of European ancestry. This is thought to be related to their increased risk of metabolic disorders...
  64. ncbi Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition Study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 32608, USA
    J Am Geriatr Soc 53:1675-80. 2005
    ..To define clinically relevant cutpoints for usual gait speed and to investigate their predictive value for health-related events in older persons...
  65. ncbi A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity
    Terry P Combs
    Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Endocrinology 145:367-83. 2004
  66. ncbi Accuracy of direct segmental multi-frequency bioimpedance analysis in the assessment of total body and segmental body composition in middle-aged adult population
    Carolina H Y Ling
    Department of Gerontology and Geriatrics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Clin Nutr 30:610-5. 2011
    b>Body composition measurement is a valuable tool for assessing nutritional status and physical fitness in a variety of clinical settings. Although bioimpedance analysis (BIA) can easily assess body composition, its accuracy remains unclear...
  67. ncbi The effect of active video gaming on children's physical activity, behavior preferences and body composition
    Lee E F Graves
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK
    Pediatr Exerc Sci 22:535-46. 2010
    ..No body fat changes were observed between groups. Targeted changes in video game use did not positively affect PA. Larger trials are needed to verify the impact of active video games on children's PA and health...
  68. ncbi Effects of progressive resistance training on body composition in frail older adults: results of a randomized, controlled trial
    Ellen F Binder
    Division of Geriatrics and Nutritional Sciences, Washington University School of Medicine, 4488 Forest Park Blvd, Suite 201, St Louis, MO 63108, USA
    J Gerontol A Biol Sci Med Sci 60:1425-31. 2005
    ..Limited information is available regarding the effects of PRT on lean and fat mass in frail elderly persons...
  69. ncbi Associations between active school transport and physical activity, body composition, and cardiovascular fitness: a systematic review of 68 studies
    Richard Larouche
    Healthy Active Living and Obesity Research Group, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    J Phys Act Health 11:206-27. 2014
    The impact of active school transport (AST) on daily physical activity (PA) levels, body composition and cardiovascular fitness remains unclear.
  70. ncbi Evaluation of the novel Tanita body-fat analyser to measure body composition by comparison with a four-compartment model
    S A Jebb
    MRC Human Nutrition Research, Cambridge, UK
    Br J Nutr 83:115-22. 2000
    ..0) kg). The present paper also describes the derivation of a new prediction equation for the calculation of body composition from the Tanita body-fat analyser...
  71. ncbi Limits of body mass index to detect obesity and predict body composition
    D C Frankenfield
    Department of Clinical Nutrition, Penn State s Milton S Hershey Medical Center, PO Box 850, Hershey, PA 17033, USA
    Nutrition 17:26-30. 2001
    ..In this study, we determined how accurately BMI could determine body composition and identify obese from non-obese individuals...
  72. pmc A critique of the expression of paediatric body composition data
    J C Wells
    Childhood Nutrition Research Centre, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Arch Dis Child 85:67-72. 2001
    There is increasing interest in body composition in paediatric research, as distinct from growth and nutritional status, as almost all diseases have adverse effects on either fatness or the fat-free mass...
  73. pmc No effects of low and high consumption of dairy products and calcium supplements on body composition and serum lipids in Puerto Rican obese adults
    Cristina Palacios
    Nutrition Program, Graduate School of Public Health, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico
    Nutrition 27:520-5. 2011
    ..The present study was conducted to determine if dairy or calcium supplementation alters body composition or serum lipids in Puerto Rican obese adults without dietary energy restriction or exercise.
  74. ncbi Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance
    V B Matthews
    Cellular and Molecular Metabolism Laboratory, Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Road Central, Melbourne, 3008, Vic, Australia
    Diabetologia 53:2431-41. 2010
    ..We aimed to determine whether global deletion of Il6 in mice (Il6 (-/-)) results in standard chow-induced and high-fat diet (HFD)-induced obesity, hepatosteatosis, inflammation and insulin resistance...
  75. pmc Effect of school-based physical activity interventions on body mass index in children: a meta-analysis
    Kevin C Harris
    Department of Pediatrics, British Columbia Children s Hospital, Vancouver, BC
    CMAJ 180:719-26. 2009
    ..We conducted a systematic review and meta-analysis to determine the effect of school-based physical activity interventions on body mass index (BMI) in children...
  76. ncbi Effect of dairy consumption on weight and body composition in adults: a systematic review and meta-analysis of randomized controlled clinical trials
    A S Abargouei
    Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
    Int J Obes (Lond) 36:1485-93. 2012
    Although several observational and experimental studies have investigated the effect of dairy consumption on weight and body composition, results are inconsistent.
  77. ncbi Testosterone treatment improves body composition and sexual function in men with COPD, in a 6-month randomized controlled trial
    J Svartberg
    Department of Medicine, University Hospital of North Norway, N 9038 Tromsø, Norway
    Respir Med 98:906-13. 2004
    The aim of this study was to assess the effect of a low-dose testosterone on body composition and pulmonary function, as well as on quality of life, sexuality, and psychological symptoms in patients with chronic obstructive pulmonary ..
  78. pmc Fluid status in peritoneal dialysis patients: the European Body Composition Monitoring (EuroBCM) study cohort
    Wim Van Biesen
    University Hospital Ghent, Ghent, Belgium
    PLoS ONE 6:e17148. 2011
    ..However, accurate tools to evaluate volume status in clinical practice and data on volume status in PD patients as compared to healthy population, and the associated factors, have not been available so far...
  79. ncbi Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society
    Dennis T Villareal
    Division of Geriatrics and Nutritional Sciences, Center for Human Nutrition, Washington University School of Medicine, St Louis, MO 63110, USA
    Obes Res 13:1849-63. 2005
    ..Therefore, weight-loss therapy that minimizes muscle and bone losses is recommended for older persons who are obese and who have functional impairments or medical complications that can benefit from weight loss...
  80. ncbi Body composition and quality of life in adults treated with GH therapy: a systematic review and meta-analysis
    Ahmad Hazem
    Knowledge and Evaluation Research Unit, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Eur J Endocrinol 166:13-20. 2012
    To summarise the evidence about the efficacy and safety of using GH in adults with GH deficiency focusing on quality of life and body composition.
  81. ncbi Early development of adiposity and insulin resistance after catch-up weight gain in small-for-gestational-age children
    Lourdes Ibanez
    Endocrinology Unit, Hospital Sant Joan de Deu, University of Barcelona, Passeig de Sant Joan de Déu, 2, 08950 Esplugues, Barcelona, Spain
    J Clin Endocrinol Metab 91:2153-8. 2006
    ..Low birth weight followed by rapid postnatal weight gain is associated with long-term risks for central obesity and insulin resistance. However, the timing of these changes is unclear...
  82. ncbi The relationship between BMI and percent body fat, measured by bioelectrical impedance, in a large adult sample is curvilinear and influenced by age and sex
    S Meeuwsen
    Bodystat Ltd, P O Box 50, Douglas, Isle of Man IM99 1DQ, United Kingdom
    Clin Nutr 29:560-6. 2010
    ..The study aimed to establish the effects of age, gender and age-gender interactions on BMI-% fat relationships over a wide range of BMI and age. It also aimed to examine controversies regarding linear or curvilinear BMI-% fat relationships...
  83. ncbi Variations in infant feeding practice are associated with body composition in childhood: a prospective cohort study
    Sian M Robinson
    Medical Research Council Epidemiology Resource Centre, University of Southampton, Southampton General Hospital, Southampton, United Kingdom
    J Clin Endocrinol Metab 94:2799-805. 2009
    Most studies of infant diet and later body composition focus on milk feeding; few consider the influence of variations in the weaning diet.
  84. pmc Effect of dietary protein content on weight gain, energy expenditure, and body composition during overeating: a randomized controlled trial
    George A Bray
    Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    JAMA 307:47-55. 2012
    ..The role of diet composition in response to overeating and energy dissipation in humans is unclear...
  85. ncbi BMI, fat mass, abdominal adiposity and visceral fat: where is the 'beef'?
    C Bouchard
    Pennington Biomedical Research Center, Baton Rouge, LA, USA
    Int J Obes (Lond) 31:1552-3. 2007
  86. ncbi Effect of a multistage ultra-endurance triathlon on body composition: World Challenge Deca Iron Triathlon 2006
    B Knechtle
    Gesundheitszentrum St Gallen, St Gallen, Switzerland
    Br J Sports Med 42:121-5; discussion 125. 2008
    To investigate the effect of a multistage ultra-endurance triathlon on body composition in ultra-triathletes.
  87. ncbi The emergence of the metabolic syndrome with menopause
    Molly C Carr
    Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle, Washington 98195 6426, USA
    J Clin Endocrinol Metab 88:2404-11. 2003
    ..A better understanding of these metabolic changes with menopause will aid in the recognition and treatment of women at risk for future CVD, leading to appropriate interventions...
  88. ncbi Body composition in psychotic disorders: a general population survey
    S E Saarni
    National Public Health Institute, Department for Mental Health and Alcohol Research, Mannerheimintie 166, 00300 Helsinki, Finland
    Psychol Med 39:801-10. 2009
    ..We examined the detailed body composition of people with different psychotic disorders in a large population-based sample.
  89. ncbi Time spent being sedentary and weight gain in healthy adults: reverse or bidirectional causality?
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 88:612-7. 2008
    ..Whether obesity is a cause or a consequence of a sedentary lifestyle has not yet been fully elucidated, which leaves uncertainty about the direction of causality...
  90. ncbi Evaluation of waist circumference, waist-to-hip ratio, and the conicity index as screening tools for high trunk fat mass, as measured by dual-energy X-ray absorptiometry, in children aged 3-19 y
    R W Taylor
    Departments of Human Nutrition, Medicine, and Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    Am J Clin Nutr 72:490-5. 2000
    ..Because adiposity tracks from childhood into adulthood, the ability of simple anthropometric techniques to correctly measure truncal adiposity in childhood needs to be assessed...
  91. ncbi The role of diet and exercise for the maintenance of fat-free mass and resting metabolic rate during weight loss
    Petra Stiegler
    Department of Human and Health Sciences, University of Westminster, London, UK
    Sports Med 36:239-62. 2006
    ..Exercise training is associated with an increase in energy expenditure, thus promoting changes in body composition and bodyweight while keeping dietary intake constant...
  92. pmc A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults
    Kim S Stote
    Beltsville Human Nutrition Research Center, US Department of Agriculture, Agriculture Research Service, Beltsville, MD, USA
    Am J Clin Nutr 85:981-8. 2007
    ..A diet with less meal frequency can improve the health and extend the lifespan of laboratory animals, but its effect on humans has never been tested...
  93. ncbi Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men
    A W van den Beld
    Department of Internal Medicine III, Erasmus University Rotterdam, The Netherlands
    J Clin Endocrinol Metab 85:3276-82. 2000 of 403 independently living elderly men, we tested the hypothesis that the decreases in bone mass, body composition, and muscle strength with age are related to the fall in circulating endogenous testosterone (T) and estrogen ..
  94. ncbi Relations of moderate and vigorous physical activity to fitness and fatness in adolescents
    Bernard Gutin
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, GA, USA
    Am J Clin Nutr 81:746-50. 2005
    ..It is unclear how moderate and vigorous intensities of physical activity (PA) are associated with cardiovascular fitness (CVF) and percentage of body fat (%BF) in adolescents...
  95. ncbi Programmed obesity in intrauterine growth-restricted newborns: modulation by newborn nutrition
    Mina Desai
    Perinatal Research Laboratories, Department of Obstetrics and Gynecology, David Geffen School of Medicine at University of California Los Angeles, Torrance, CA, USA
    Am J Physiol Regul Integr Comp Physiol 288:R91-6. 2005
    ..of nutrient enhancement during the newborn period may modulate programming of appetite-regulating hormones, body composition, and propensity to adult obesity in intrauterine growth-restricted (IUGR) newborns...
  96. ncbi Body-composition assessment via air-displacement plethysmography in adults and children: a review
    David A Fields
    Department of Internal Medicine, The Center for Human Nutrition, Washington University, St Louis, USA
    Am J Clin Nutr 75:453-67. 2002
    ..Wide intersubject variations between methods are partly attributed to technical precision and biological error but to a large extent remain unexplained. On the basis of this review, future research goals are suggested...
  97. ncbi Pediatric reference data for lean tissue properties: density and hydration from age 5 to 20 y
    Jonathan C K Wells
    Institute of Child Health, London, UK
    Am J Clin Nutr 91:610-8. 2010
    Hydrometry and densitometry are widely used to assess pediatric body composition due to their ease of application...
  98. pmc DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status
    Kevin D Sinclair
    School of Biosciences and School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Leicestershire LE12 5RD, United Kingdom
    Proc Natl Acad Sci U S A 104:19351-6. 2007
  99. ncbi Age and sex effects on the association between body composition and bone mineral density in healthy Chinese men and women
    Qun Cheng
    Shanghai Geriatric Institute, Department of Osteoporosis, Research Section of Geriatric Metabolic Bone Disease, Huadong Hospital, Fudan University, Shanghai, People s Republic of China
    Menopause 19:448-55. 2012
    Many studies have examined the relationships between body composition and bone mineral density (BMD), but little attention has been given to how these relationships vary by age and sex...
  100. pmc Effects of metformin on body weight and body composition in obese insulin-resistant children: a randomized clinical trial
    Jack A Yanovski
    Unit on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD, Bethesda, Maryland, USA
    Diabetes 60:477-85. 2011
    ..Our objective was to determine whether metformin treatment causes weight loss and improves obesity-related comorbidities in obese children, who are insulin-resistant...

Research Grants73

  1. Bone Deficits and Excess Adiposity after Pediatric Bone Marrow Transplantation
    Sogol Mostoufi-Moab; Fiscal Year: 2013
    ..published the first comprehensive studies of trabecular bone mineral density (BMD), cortical structure, and body composition in 55 long-term survivors of childhood HSCT...
  2. Effects of Evoked Resistance Training and Testosterone after Spinal Cord Injury
    Ashraf Gorgey; Fiscal Year: 2012
    ..disorders such as glucose intolerance, insulin resistance and dyslipidemia secondary to deterioration in body composition. Within few weeks of injury, there are significant decrease in whole body fat-free mass (FFM), particularly ..
  3. Pituitary dysfunction, behavioral symptoms, and quality of life after blast mTBI
    ..anxiety, depression, irritability, insomnia, and decreased quality of life (QoL), as well as changes in body composition including increased fat percentage, hyperlipidemia, and a decrease in muscle mass...
  4. Response to and signals of caloric restriction and intermittent feeding regimens
    MARC KOPEL HELLERSTEIN; Fiscal Year: 2010
    ..fasting (mADF) reproduce many of the benefits of true CR in mice, without weight loss or change in body composition. Biomarkers that respond to CR and certain mADF regimens include global cell proliferation (mammary, prostate,..
  5. Comparative Resistance Exercise Effects on Knee Osteoarthritis Pain, Functional I
    KEVIN ROBERT VINCENT; Fiscal Year: 2013
    ..Men and women with OA related knee pain will be eligible for this study. Demographics, body composition, OA history and severity will be collected as descriptive variables...
    Michael J LaMonte; Fiscal Year: 2013
    ..radiographs for alveolar crestal height (ACH);dual energy x-ray absorptiometry (DXA) for bone density and body composition;questionnaires on lifestyle habits, oral hygiene and medical history;resting blood pressure;and a fasting ..
  7. Pathogenesis of the Metabolic Syndrome
    W Timothy Garvey; Fiscal Year: 2013
    ..resistant subjects, and patients with T2DM will be metabolically characterized by hyperinsulinemic clamps, body composition, IMCL, energy expenditure and substrate oxidation rates, and will be studied before and after perturbations ..
  8. Weight Loss &Exercise Effects on Telomere Length in Postmenopausal Women
    ANNE M MCTIERNAN; Fiscal Year: 2012
    ..effects of dietary weight loss and exercise on telomere length and 2) the amount of weight loss, or change in body composition that may be necessary to effect changes in telomere length...
    Jessica A Whiteley; Fiscal Year: 2011
    ..control have identified a number of limitations including 1) small sample sizes, 2) inadequate measures of body composition, 3) inattention to the impact of physical development in the analyses, 4) failure to disaggregate results for ..
  10. Undercarboxylated osteocalcin, body fat, and diabetes in older adults
    Ann V Schwartz; Fiscal Year: 2010
    ..of older adults, this research project will use data and biological specimens from the Health, Aging and Body Composition (Health ABC) study, a cohort of 3,075 men and women, white and African-American, aged 70-79 years at baseline...
  11. Effects of Gastric Bypass Surgery on Calcium Metabolism and the Skeleton
    ANNE LOUISE SCHAFER; Fiscal Year: 2013
    ..decreased skeletal loading, and changes in fat-secreted hormones or estrogen (due to changes in fat mass and body composition). Dr...
  12. Maternal One Carbon Metabolism and Low Birth Weight Infant
    Satish C Kalhan; Fiscal Year: 2013
    ..These physiological data will be related to fetal growth as assessed by birth weight and body composition, and metabolic and hormonal assessments in the cord blood...
  13. Secondary Muscle Pathology &Metabolic Dysregulation in Adult with Cerebral Palsy
    Mark Peterson; Fiscal Year: 2013
    ..Research Unit (MCRU) to learn dual-energy X-ray absorptiometry quantification of whole body and regional body composition, 3) Dr...
  14. Lifespan Extension Despite Greatly Elevated Insulin and Body Fat
    David E Harrison; Fiscal Year: 2013
    ..The following will be determined: body composition and subcutaneous/visceral fat tissue distribution (using computerized tomography imaging);circulating ..
  15. Calorie Restriction &Body Composition, Function, &QoL in Older Adults
    Julie L Locher; Fiscal Year: 2013
    ..minimize risk with weight reducing diets in older adults may be in understanding how age-related changes in body composition, in addition to excess weight gain, affect cardiometabolic risk factors and functional status...
  16. A Prospective Study of Adiposity and Subclinical Coronary Artery Disease
    CHRISTINA LYNN WASSEL; Fiscal Year: 2010
    ..Recent studies indicate that other measures of body composition, including lean muscle and intermuscular, liver and pericardial fat, are correlated with adipocytokines and ..
  17. Metabolic Actions of Omega-3 Fatty Acids on Inflammation
    Michael Miller; Fiscal Year: 2013
    ..quantified as, visceral and subcutaneous adipose volumes and muscle lipid accumulation by CT-scan and body composition (total and regional fat mass) by dual energy absorptiometry (DXA)...
  18. Masked Hypertension in Chronic Kidney Disease
    Rajiv Agarwal; Fiscal Year: 2013
    ..Sleep will be measured using portable multichannel overnight sleep monitoring. Body composition will be measured by the gold-standard measurement of air-displacement plethysmography (Bod Pod)...
  19. Body composition, bone structure, and joint damage in rheumatoid arthritis
    Joshua F Baker; Fiscal Year: 2013 includes additional NIH-funded leaders in biostatistics, epidemiology, bone metabolism, body composition, and rheumatic disease, each of whom is dedicated to a coordinated effort to ward the success of his career...
  20. VITamin D and OmegA-3 TriaL: Effects on Bone Structure and Architecture
    MERYL SUSAN LEBOFF; Fiscal Year: 2013
    ..placebo on bone health and body composition outcomes...
  21. Effect of Perinatal Diet on Developmental Programming of the Skeleton
    Mary L Bouxsein; Fiscal Year: 2010
    ..Bone mineral density and body composition will be measured in vivo using peripheral dual-energy X-ray absorptiometry;cortical and trabecular bone ..
  22. Metabolic Syndrome and Breast Cancer: Effects of a Combined Exercise Intervention
    Christina Dieli-Conwright; Fiscal Year: 2013
    ..whether a 16-week exercise intervention will improve components of metabolic syndrome by measuring changes in body composition, waist circumference, blood pressure, resting energy expenditure (REE), and serum levels of insulin, glucose, ..
  23. Vitamin D Effect on Body Composition During Behavioral Weight Loss in Women
    ANNE M MCTIERNAN; Fiscal Year: 2013
    ..However, the relationships between vitamin D and specific components of body composition have not been well characterized in older populations...
  24. Mechanisms for the Effects of Hypothalamic PTP1B on Energy Balance
    KARYN JOANNE CATALANO; Fiscal Year: 2010
    ..the role of PTP1B regulation in these neurons by looking at the effect of PTP1B deletion on body weight, body composition using dual energy x-ray absorptiometry, energy expenditure using indirect calorimetry, and glucose metabolism ..
  25. NKT cells, fatty acids, and insulin resistance
    CURTIS LEE GABRIEL; Fiscal Year: 2010
    ..Specifically, we will measure weight gain, body composition, insulin resistance, and expression of pro-inflammatory genes in adipose tissue...
  26. Conservative Versus Dialytic Management in Stage V Chronic Kidney Disease
    GLENN MATTHEW CHERTOW; Fiscal Year: 2010
    ..physical function, physical activity, cognitive function, mental health, nutritional and inflammatory status, body composition, blood pressure and pulse wave velocity, hospitalization rate and number of hospital days...
  27. Prenatal stress biology, infant body composition and obesity risk
    Sonja Entringer; Fiscal Year: 2013 to examine the influence of adverse intrauterine conditions, or prenatal stress, on newborn and infant body composition and obesity risk. Obesity is one of the most important health issues facing our nation...
  28. Role of Sirt1 in Regulating Glucose Homeostasis and Insulin Action in Aging
    COLETTE M KNIGHT; Fiscal Year: 2012
    ..Finally, we will also administer resveratrol orally over several weeks to determine its effects on body composition, insulin sensitivity, metabolic markers and inflammation in adipose tissue and adispose tissue macrophages in ..
  29. Neonatal Programming of Growth and Maturation in Rhesus Monkeys
    Andrew Muir; Fiscal Year: 2013
    ..In rhesus monkeys, maternal body composition and gestational diet alter the growth and metabolism of the infants...
  30. The Effect of Behavioral and Physiological Factors on Obesity Risk in Children
    Karen B Dorsey; Fiscal Year: 2012
    ..on exercise tests relates to directly measured physical activity levels and to clinical measures of body composition. She will use a longitudinal analysis to determine whether performance on exercise tests and/or directly ..
  31. Exploring the Impact of Negative Energy Balance in Men with Prostate Cancer
    Wendy Demark-Wahnefried; Fiscal Year: 2013
    ..wait-list control arms, and also monitor changes in body composition, energy intake and PA;these changes will be studied in relation to the following endpoints: a) changes in ..
  32. Saliva and Serum Inflammatory Biomarkers in Periodontitis: A Study in Older Women
    Jean Wactawski Wende; Fiscal Year: 2010
    ..Assessments of bone density (DXA), body composition and other physical measures were obtained...
  33. Growth and Cardiometabolic Risk Among In Utero Drug Exposed Children
    SARAH ELIZABETH MESSIAH; Fiscal Year: 2013
    ..To longitudinally compare anthropometric measures (height, weight, body mass index, waist circumference, and body composition) among urban, African American children and adolescents who were or were not prenatally exposed to cocaine ..
  34. Attenuation of androgen deprivation therapy-induced metabolic syndrome by diet
    Oleg Varlamov; Fiscal Year: 2013
    ..Changes in energy balance, cytokine levels, insulin sensitivity, and body composition will be monitored in a longitudinal fashion, and the metabolic function of subcutaneous and visceral WAT will ..
  35. New Approaches to the Evaluation and Treatment of Acromegaly
    Pamela U Freda; Fiscal Year: 2013
    ..This recent work has identified novel changes in body composition in patients with acromegaly...
  36. Phosphoprotein CDP138 regulates glucose metabolism
    ZHEN YUE JIANG; Fiscal Year: 2013
    ..the physiological significance of CDP138 in vivo, by comparing insulin sensitivity, glucose disposal, body composition and metabolic rate in CDP138 knockout mice and their wild-type littermates fed with a normal chow or a high-..
  37. Role of maternal exercise environment on transgenerational offspring health
    Stephen M Roth; Fiscal Year: 2010
    ..The offspring of exercised rodent dams or human mothers have altered body composition, organ weights, metabolism and/or behavioral patterns...
  38. Proinflammatory Biomarkers and Post-Breast CancerLymphedema
    Mei Rosemary Fu; Fiscal Year: 2012
    ..period, including: (1) measuring and comparing LVC using the infra-red perometer, LE symptoms, BMI and body composition;(2) evaluating levels and patterns of proinflammatory biomarkers in relation to LVC;and (3) evaluating ..
  39. Regulation of Maternal Fuel Supply and Neonatal Adiposity
    LINDA ANNE BARBOUR; Fiscal Year: 2013
    ..that maternal obesity and diabetes create an intrauterine environment promoting fetal overgrowth which alters body composition at birth and may potentiate the risk of childhood obesity...
  40. The altered lipid and protein metabolism of pediatric patients with HIV infection
    Farook Jahoor; Fiscal Year: 2010
    ..Measure body composition by DEXA, plasma lipid profile, plasma fatty acid appearance rate in the fasted and fed states, fatty acid ..
  41. Safe and Effective Vitamin D Supplementation in HIV
    Virginia A Stallings; Fiscal Year: 2012 160 ng/mL), improved cathecidin mRNA expression, and measures of bone, muscle, inflammation, growth and body composition status, and HIV/AIDS disease severity...
  42. The Role of FoxO1 in the Regulation of the Adipocyte Browning Response
    JOSHUA ROBERT COOK; Fiscal Year: 2013
    ..g., body weight, body composition, adipose-tissue depot weights) and assays of insulin sensitivity at both the levels of whole-body (e.g...
  43. Eicosapentaenoic acid and protein modulation to induce anabolism in COPD
    MARIELLE PKJ ENGELEN; Fiscal Year: 2012
    ..The combination of plasma and muscle tissue sampling, stable isotope methodology, and assessment of body composition, functional status and quality of life will enable quantification of all endpoints...
  44. Metabolic and Energetic Consequences of Fatherhood
    Wendy Saltzman; Fiscal Year: 2013
    ..hormones, one possibility is that these endocrine profiles influence energy homeostasis, metabolism, and body composition, which in turn can affect health and longevity...
  45. Modulation of PPAR-gamma phosphorylation at S273 regulates insulin sensitivity
    ALEXANDER BANKS; Fiscal Year: 2013
    ..Following the induction of diet-induced obesity in these mice, we will examine body composition, glucose homeostasis and PPAR-gamma target gene expression in adipose tissue from obese mice...
  46. Inflammatory Cytokine regulation of POMC and Orexin neurons in cachexia.
    AARON GROSSBERG; Fiscal Year: 2012
    ..neurons will be evauated histochemically and correlated to measurements of motor activity, food intake, and body composition. A central cytokine administration model of cachexia will also be utilized, and the effectiveness of orexin ..
  47. Impact of Exercise on Body Composition in Premature Infants: New Approaches
    Dan M Cooper; Fiscal Year: 2013
    ..The potential beneficial impact of augmented physical activity on 1) body composition, 2) associated biochemical and cellular mechanisms of growth and inflammation, and 3) quality of maternal ..
    JASON J HASSENSTAB; Fiscal Year: 2013
    ..At baseline and follow- up, all participants will complete glucose clamp testing, body composition assessment, blood tests, blood pressure checks, comprehensive psychometric assessment, brief psychiatric ..
  49. The Role of Mitochondrial Toxicity in Metabolic Complications of Pediatric HIV
    TANVI SHAH SHARMA; Fiscal Year: 2013
    ..Our aims are to first characterize body composition abnormalities, nutritional issues, and metabolic complications in HIV-infected children by analyzing a large, ..
  50. Insulin Resistance in Chronic Kidney Disease
    Ian H De Boer; Fiscal Year: 2013
    ..These include the Institute for Translational Health Sciences Clinical Research Center, Nutrition and Body Composition Core, and Center for Biomedical Statistics.
  51. Insulin Resistance in Chronic Heart Failure: pathophysiology and potential for re
    Nir Uriel; Fiscal Year: 2013
    ..Total body fat, organ specific fat, and muscle mass will be measured in HF subjects to control for body composition. We will then evaluate exercise-induced changes in circulating FFA using cardiopulmonary exercise testing (..
  52. Maternal Overweight: Consequences for Insulin Signaling in the Offspring
    Kartik Shankar; Fiscal Year: 2013
    ..composition and life-style factors such as physical activity undoubtedly have important roles in determining body composition, maternal overweight (OW) status ( BMI >25) at conception may be a critical synergizing factor...
  53. Body Composition and Energy Utilization in Spinal Muscular Atrophy
    Douglas Michael Sproule; Fiscal Year: 2012
    ..Unfortunately, although nutrition and body composition are a modifiable factors of potential importance in the optimal clinical management of patients with SMA, ..
    Clinton T Rubin; Fiscal Year: 2012
    ..Three specific aims are designed to better understand the means by which LMMS influences the body composition of the growing, aging, obese and diseased animal: 1...
  55. Regulation of Brain Signaling After Bariatric Surgery
    Jonathan Q Purnell; Fiscal Year: 2010
    ..They will also complete measures of body composition, visual analog scores for hunger and satiety, and adlibitum food intake...
  56. Do Genotype Patterns Predict Weight Loss Success for Low Carb vs. Low Fat Diets?
    Christopher D Gardner; Fiscal Year: 2013
    ..24-hour recalls, NDS-R), appetite/satiety/hunger, energy expenditure (resting energy expenditure), body composition (DEXA), and blood variables (lipids, insulin, glucose, OGTT)...
  57. Bone Marrow Adiposity, Bone and Body Composition
    Ann V Schwartz; Fiscal Year: 2012
    ..A better understanding of the process underlying the accumulation of marrow fat with age and osteoporosis may provide new targets for treatments to prevent bone loss. ..
  58. Genetic analysis fo metabolic syndrome by admixture mapping in African Americans
    Ludmila Pawlikowska; Fiscal Year: 2012
    ..cohort of 2000 African-Americans from the Cardiovascular Health Study (CHS) and the Health, Aging and Body Composition Study (HABC)...
  59. Mitochondrial Determinants of Metabolic Disease in HIV-Infected Children
    Tracie L Miller; Fiscal Year: 2013
    ..complications, including metabolic abnormalities such as insulin resistance, diabetes mellitus, and body composition changes...
  60. Effects of gastric bypass on the gut microbiota and energy balance
    Alice Liou; Fiscal Year: 2012
    ..gut microbial contributions to multiple aspects of metabolic regulation on both a physiological and molecular level, including food intake, fat deposition and body composition, energy expenditure, lipid metabolism and glucose metabolism.
  61. Mechanisms of Cancer Treatment Related Symptoms
    Lisa J Wood; Fiscal Year: 2013
    ..decreased appetite, sleep disturbance, difficulty thinking, anemia, pain, depressed mood and changes in body composition. These symptoms can greatly influence the subjective sensation of cancer treatment related fatigue (CTRF) ..
  62. Stimulated by Retinoic Acid (STra6) in Energy Homeostasis
    LAURA H ZEMANY; Fiscal Year: 2013
    ..Glucose metabolism, insulin sensitivity, body composition, and energy expenditure will be studied in mice treated with STRA6 antisense oligonucleotides and in the ..
  63. Fetal Programming and Human Physical Performance
    Tom Brutsaert; Fiscal Year: 2009
    ..We will also measure body composition via hydro-densitometry and insulin resistance via an oral glucose tolerance test, both before and after ..
    Alan Rogol; Fiscal Year: 1999
    We hypothesize that alterations in growth, 4 compartment of body composition (BC), regional distribution of body fat (RDBF; via MRI, anthropometry), and bone mineralization (BM; via DEXA) in boys and girls are driven by alterations in GH ..
  65. Childhood Origins for Cardiac Structure and Function
    Shumei S Sun; Fiscal Year: 2012
    ..portion of the FLS data set includes serial anthropometric and blood pressure measurements from birth---and body composition measurements from age eight years---through adulthood in 750 participants who consented to undergo ..
  66. Nutritional Intervention for Age-Related Muscular Function and Strength Losses
    John A Rathmacher; Fiscal Year: 2010
    ..0 g/d + 2,000 IU Vitamin D. The subjects will undergo a 3-day per week exercise program, and body composition and strength will be measured at four week intervals...
    Scott Going; Fiscal Year: 1991
    Accurate estimation of body composition in middle-aged and elderly individuals is limited by a lack of knowledge of the fat free body (FFB) composition in this age group...
    Richard Boileau; Fiscal Year: 1992
    b>Body composition assessment is an important aspect in evaluating health, nutritional status and physical fitness...
    Barbara Sternfeld; Fiscal Year: 2001
    Vigorous physical training, either independently or in conjunction with factors such as weight, body composition and/or energy intake, is associated with various disruptions in ovarian function, including oligo/amenorrhea, shortened ..
    Linda Van Eldik; Fiscal Year: 2009
    ..Phenotyping will includeanthropometry and body composition, as well as factors associated with the development of obesity: energy partitioning during growth, energy ..
  71. Metabolic and Nutritional Effects of ART in Children
    Meera Chhagan; Fiscal Year: 2009
    ..Specific aims of this study are to: 1) describe growth and body composition changes in the 2 years following initiation of ART;2) describe the incidence of metabolic derangements and ..
  72. Weight Loss and Exercise in Frail Obese Elderly Subjects
    DENNIS VILLAREAL; Fiscal Year: 2009
    ..are to evaluate the independent and combined effects of weight loss and exercise on physical function, body composition, bone and muscle metabolism, and quality of life in frail, obese elderly men and women...
  73. Genetic and Environmental Influences on Childhood Growth
    Bradford Towne; Fiscal Year: 2006 regular intervals from approximately 900 boys and girls a comprehensive battery of growth, maturation, body composition, and health status measures, as well as information on specific environmental factors that likely impact the ..