- The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society
Neurourol Urodyn 21:167-78. 2002
- Expression of flagella is coincident with uropathogenic Escherichia coli ascension to the upper urinary tract
M Chelsea Lane
Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109 0620, USA
Proc Natl Acad Sci U S A 104:16669-74. 2007
Uropathogenic Escherichia coli (UPEC) cause most uncomplicated urinary tract infections (UTIs) in humans...
- Interstitial cell of Cajal-like cells in the upper urinary tract
R J Lang
Department of Physiology, Faculty of Medicine and Health Sciences, Monash University, Clayton, 3168, Victoria, Australia
J Cell Mol Med 9:543-56. 2005
Autorhythmicity in the upper urinary tract (UUT) has long been considered to arise in specialized atypical smooth muscle cells (SMC) predominately situated in the most proximal regions of the pyeloureteric system...
- Characterization of urine-derived stem cells obtained from upper urinary tract for use in cell-based urological tissue engineering
Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27101, USA
Tissue Eng Part A 17:2123-32. 2011
The goals of this study were to characterize urine-derived stem cells obtained from the upper urinary tract (uUSC), induce these cells to differentiate into urothelial and smooth muscle cells, and determine whether they could serve as a ..
- Human alpha defensin 5 expression in the human kidney and urinary tract
John David Spencer
Pediatric Nephrology Fellowship Program, Nationwide Children s Hospital, Columbus, Ohio, United States of America
PLoS ONE 7:e31712. 2012
The mechanisms that maintain sterility in the urinary tract are incompletely understood. Recent studies have implicated the importance of antimicrobial peptides (AMP) in protecting the urinary tract from infection...
- Ribonuclease 7 is a potent antimicrobial peptide within the human urinary tract
John D Spencer
Pediatric Nephrology Fellowship Program, Nationwide Children s Hospital, The Ohio State University, Columbus, Ohio, USA
Kidney Int 80:174-80. 2011
Although the urinary tract is constantly challenged by microbial invasion, it remains free from colonization...
- Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract
Indira U Mysorekar
Department of Molecular Microbiology, Washington University School of Medicine, Box 8230, 660 South Euclid Avenue, St Louis, MO 63110, USA
Proc Natl Acad Sci U S A 103:14170-5. 2006
Recurrent urinary tract infections (rUTIs) are a source of considerable morbidity in women. The infecting bacteria in both rUTIs and a de novo acute infection have been thought to originate from an extraurinary location...
- Uropathogenic Escherichia coli flagella aid in efficient urinary tract colonization
Kelly J Wright
Department of Molecular Microbiology, Box 8230, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
Infect Immun 73:7657-68. 2005
In the murine model of urinary tract infections (UTI), cystitis by uropathogenic Escherichia coli (UPEC) occurs through an intimate relationship with the bladder superficial umbrella cell entailing cycles of adherence, invasion, ..
- Genetic and developmental basis for urinary tract obstruction
Renal Division, Department of Internal Medicine, Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO 63110, USA
Pediatr Nephrol 24:1621-32. 2009
b>Urinary tract obstruction results in obstructive nephropathy and uropathy. It is the most frequent cause of renal failure in infants and children...
- Phosphodiesterase type 5 expression in human and rat lower urinary tract tissues and the effect of tadalafil on prostate gland oxygenation in spontaneously hypertensive rats
Department of Clinical Physiopathology, Sexual Medicine and Andrology Unit, University of Florence, Florence, Italy
J Sex Med 8:2746-60. 2011
- Fstl1 antagonizes BMP signaling and regulates ureter development
MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China
PLoS ONE 7:e32554. 2012
Bone morphogenetic protein (BMP) signaling pathway plays important roles in urinary tract development although the detailed regulation of its activity in this process remains unclear...
- Lower urinary tract phenotype of experimental autoimmune cystitis in mouse: a potential animal model for interstitial cystitis
Yi Hao Lin
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan
BJU Int 102:1724-30. 2008
..To examine bladder function in a newly developed experimental autoimmune cystitis (EAC) model in female SWXJ strain mice, as a potential animal model for interstitial cystitis (IC)...
- Urinary tract infections caused by Pseudomonas aeruginosa: a minireview
Division of Infectious Diseases, Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA
J Infect Public Health 2:101-11. 2009
b>Urinary tract infections (UTIs) are a serious health problem affecting millions of people each year. Infections of the urinary tract are the second most common type of infection in the body...
- Tailbud-derived mesenchyme promotes urinary tract segmentation via BMP4 signaling
Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, NY 10021, USA
Development 134:1967-75. 2007
b>Urinary tract morphogenesis requires the sub-division of the ureteric bud (UB) into the intra-renal collecting system and ureter, two tissues with unique structural and functional properties...
- Anorectal malformations caused by defects in sonic hedgehog signaling
Program in Developmental Biology, University of Toronto, Toronto, Ontario, Canada
Am J Pathol 159:765-74. 2001
- Antimicrobial peptides, innate immunity, and the normally sterile urinary tract
Division of Surgical Immunology, Department of Surgery, Georgetown University School of Medicine, Washington, DC, USA
J Am Soc Nephrol 18:2810-6. 2007
..Epithelia lining the urinary tract prevent adhesion of bacteria by release of Tamm-Horsfall protein, lactoferrin, lipocalin, and constitutive and ..
- Genetics of congenital anomalies of the kidney and urinary tract
Section of Pediatric Nephrology, Department of Pediatrics, Hypertension and Renal Center of Excellence, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
Pediatr Nephrol 26:353-64. 2011
Congenital anomalies of the kidney and urinary tract (CAKUT) occur in 1 in 500 births and are a major cause of morbidity in children...
- Muscarinic receptor subtypes in the lower urinary tract
Department of Pharmacology, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Pharmacology 83:259-69. 2009
..review describes signalling mechanisms, expression and functional effects of muscarinic receptors in the lower urinary tract. Their roles in physiological and pathophysiological conditions, as well as clinical implications of the ..
- Vanilloid receptor 1 expression in the rat urinary tract
Institute of Histology and Embryology, Faculty of Medicine of Oporto, IBMC of University of Oporto, Porto, Portugal
Neuroscience 109:787-98. 2002
..the distribution, morphology and the neurochemical content of nerve fibres expressing this receptor in the rat urinary tract. Immunolabelling was performed against the VR1 and the positive fibres were examined by light and electron ..
- Epidemiology of urinary tract infections: transmission and risk factors, incidence, and costs
Department of Epidemiology, Center for Molecular and Clinical Epidemiology of Infectious Diseases, University of Michigan School of Public Health, 109 Observatory Street, Ann Arbor, MI 48109 2029, USA
Infect Dis Clin North Am 17:227-41. 2003
..The benefits of successfully preventing UTI are substantial...
- Innate and adaptive immune responses in the urinary tract
Department of Molecular Genetics and Microbiology, Duke University Medical Centre, Durham, NC 27710, USA
Eur J Clin Invest 38:21-8. 2008
As new and intriguing details of how uropathogens initiate infections and persist within the urinary tract have emerged, so has important information regarding how the immune system functions within the urinary tract...
- Enterococcal aggregation substance and binding substance are not major contributors to urinary tract colonization by Enterococcus faecalis in a mouse model of ascending unobstructed urinary tract infection
James R Johnson
Mucosal and Vaccine Research Center, VA Medical Center and Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55417, USA
Infect Immun 72:2445-8. 2004
..These data suggest that AS and EBS do not contribute to upper or lower urinary tract colonization by E...
- Traditional and targeted exome sequencing reveals common, rare and novel functional deleterious variants in RET-signaling complex in a cohort of living US patients with urinary tract malformations
Department of Internal Medicine Renal Division, Washington University School of Medicine, Box 8126, 660 S Euclid Ave, St Louis, MO 63110, USA
Hum Genet 131:1725-38. 2012
..neurotrophic factor (GDNF)-RET receptor tyrosine kinase and SPRY1, a RET repressor, is essential for early urinary tract development...
- Renal outcome in patients with congenital anomalies of the kidney and urinary tract
Division of Nephrology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
Kidney Int 76:528-33. 2009
Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) are a major cause of morbidity in children...
- Mutations in SOX17 are associated with congenital anomalies of the kidney and the urinary tract
Biologia Generale e Genetica Medica, Universita di Pavia, Pavia, Italy Service of Genetic Medicine, University Hospitals of Geneva, Geneva, Switzerland
Hum Mutat 31:1352-9. 2010
Congenital anomalies of the kidney and the urinary tract (CAKUT) represent a major source of morbidity and mortality in children...
- Immune modulation by group B Streptococcus influences host susceptibility to urinary tract infection by uropathogenic Escherichia coli
Kimberly A Kline
Department of Molecular Microbiology, Center for Women s Infectious Disease Research, Washington University School of Medicine, St Louis, Missouri, USA
Infect Immun 80:4186-94. 2012
b>Urinary tract infection (UTI) is most often caused by uropathogenic Escherichia coli (UPEC)...
- Rates of urinary tract injury from gynecologic surgery and the role of intraoperative cystoscopy
D T Gilmour
Department of Obstetrics and Gynecology, Dalhousie University, Halifax, Nova Scotia, Canada
Obstet Gynecol 107:1366-72. 2006
To estimate the rates of urinary tract injury after benign gynecologic surgery. To explore the role of routine intraoperative cystoscopy at benign gynecologic surgery.
- Urinary tract infection
Lindsay E Nicolle
Department of Internal Medicine, Health Sciences Centre, University of Manitoba, Room GG443, 820 Sherbrook Street, Winnipeg, Manitoba R3A 1R9, Canada
Crit Care Clin 29:699-715. 2013
The urinary tract is a common source for life-threatening infections. Most patients with sepsis or septic shock from a urinary source have complicated urinary tract infection...
- Complicated urinary tract infections
Durwood E Neal
Division of Urology, Department of Surgery, University of Missouri, Columbia, MO 65212, USA
Urol Clin North Am 35:13-22; v. 2008
A complicated urinary tract infection is that which occurs in a patient with an anatomically abnormal urinary tract or significant medical or surgical comorbidities...
- Type 1 fimbriae and extracellular polysaccharides are preeminent uropathogenic Escherichia coli virulence determinants in the murine urinary tract
Farah K Bahrani-Mougeot
Division of Infectious Diseases, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Mol Microbiol 45:1079-93. 2002
Escherichia coli is the leading cause of urinary tract infections (UTIs). Despite the association of numerous bacterial factors with uropathogenic E. coli (UPEC), few such factors have been proved to be required for UTI in animal models...
- Polymerase chain reaction-based identification of Propionibacterium acnes types isolated from the male urinary tract: evaluation of adolescents, normal adults and men with prostatic pathology
Beverley A Shannon
Tissugen Pty Ltd, Perth, Western Australia
BJU Int 98:388-92. 2006
To assess whether colonization of the male urinary tract with Propionibacterium acnes, in particular types IB and II (which are associated with inflammation in radical prostatectomy specimens and might be involved in the development of ..
- Maintaining a sterile urinary tract: the role of antimicrobial peptides
Ased S M Ali
Newcastle University, Newcastle upon Tyne, United Kingdom
J Urol 182:21-8. 2009
The normally sterile urinary tract is constantly challenged by microbial invasion leading to a high prevalence of isolated, recurrent and catheter associated urinary tract infection...
- Cre/lox recombination in the lower urinary tract
Department of Internal Medicine, Renal Division, Washington University School of Medicine, St Louis, MO 63110, USA
Genesis 47:409-13. 2009
Tbx18 is a T-Box transcription factor that has specific expression and indispensible function in the lower urinary tract. Here, we report the generation and characterization of a bacterial artificial chromosome (BAC) transgene expressing ..
- Covert operations of uropathogenic Escherichia coli within the urinary tract
Jean M Bower
Pathology Department, Division of Cell Biology and Immunology, University of Utah School of Medicine, 30 North 1900 East, Salt Lake City, Utah 84132 2501, USA
Traffic 6:18-31. 2005
..Among these are strains of uropathogenic Escherichia coli (UPEC), the primary causative agents of urinary tract infections (UTIs)...
- Urinary tract infection due to Achromobacter xylosoxidans: report of 9 cases
Section of Microbiology, University Hospital of Guadalajara, Guadalajara, Spain
Scand J Infect Dis 40:84-7. 2008
b>Urinary tract infection (UTI) due to Achromobacter xylosoxidans is rare. The aims were to know the frequency and clinical characteristics of this infection in our area...
- Hirschsprung disease and congenital anomalies of the kidney and urinary tract (CAKUT): a novel syndromic association
Alessio Pini Prato
Department of Pediatric Surgery, Giannina Gaslini Institute, Genoa, Italy
Medicine (Baltimore) 88:83-90. 2009
Congenital anomalies of the kidney and urinary tract (CAKUT) can be associated with Hirschsprung disease (HSCR)...
- Mutations in DSTYK and dominant urinary tract malformations
Division of Nephrology, Columbia University, New York, NY 10032, USA
N Engl J Med 369:621-9. 2013
Congenital abnormalities of the kidney and the urinary tract are the most common cause of pediatric kidney failure. These disorders are highly heterogeneous, and the etiologic factors are poorly understood.
- CHD1L: a new candidate gene for congenital anomalies of the kidneys and urinary tract (CAKUT)
Institute of Human Genetics, Rheinische Friedrich Wilhelms University, Bonn, Germany
Nephrol Dial Transplant 27:2355-64. 2012
Recently, we identified a microduplication in chromosomal band 1q21.1 encompassing the CHD1L/ALC1 gene encoding a chromatin-remodelling enzyme in congenital anomalies of the kidneys and urinary tract (CAKUT) patient.
- Abolition of biofilm formation in urinary tract Escherichia coli and Klebsiella isolates by metal interference through competition for fur
Microbial Adhesion Group, DTU Food, Bldg 301, Technical University of Denmark, DK 2800 Lyngby, Denmark
Appl Environ Microbiol 76:3836-41. 2010
..In the urinary tract, free iron is strictly limited but is critical for bacterial growth...
- Sacral neuromodulation for neurogenic lower urinary tract dysfunction: systematic review and meta-analysis
Thomas M Kessler
Department of Urology, University of Bern, Bern, Switzerland
Eur Urol 58:865-74. 2010
Treatment of neurogenic lower urinary tract dysfunction (LUTD) is a challenge, because conventional therapies often fail...
- Mutation analysis of the Uromodulin gene in 96 individuals with urinary tract anomalies (CAKUT)
Matthias T F Wolf
Department of Pediatrics, University of Michigan, Ann Arbor, MI, USA
Pediatr Nephrol 24:55-60. 2009
..Mutations in HNF1B cause a phenotype similar to FJHN/GCKD but also congenital anomalies of the kidney and the urinary tract (CAKUT). Moreover, we recently detected UMOD mutations in two patients with CAKUT...
- Immunohistochemical analysis of Sonic hedgehog signalling in normal human urinary tract development
Nephro Urology, and Clinical and Molecular Genetics Units, UCL Institute of Child Health, UK
J Anat 211:620-9. 2007
..signalling has a functional role in morphogenesis and differentiation at multiple sites within the forming urinary tract, and urinary tract malformations have been reported in humans with mutations that disrupt SHH signalling...
- Toll-like receptors recognize uropathogenic Escherichia coli and trigger inflammation in the urinary tract
Hans Joachim Anders
Nephrol Dial Transplant 20:1529-32. 2005
- Emerging antibiotic resistance in urinary tract pathogens
Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington School of Medicine, BB1221, Box 356523, Seattle, WA 98195, USA
Infect Dis Clin North Am 17:243-59. 2003
..In the meantime, ongoing surveillance of resistance trends and enhanced understanding of the determinants of resistance are crucial for optimal management of UTIs...
- Outcome of isolated antenatal hydronephrosis: a prospective cohort study
Graziela M Coelho
Pediatric Nephrourology Unit, Department of Pediatrics, Hospital das Clinicas, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil
Pediatr Nephrol 22:1727-34. 2007
..The events of interest were: presence of uropathy, need for surgical intervention, RPD resolution, urinary tract infection (UTI), and hypertension. RPD was classified as mild (5-9.9 mm), moderate (10-14...
- Mapping candidate regions and genes for congenital anomalies of the kidneys and urinary tract (CAKUT) by array-based comparative genomic hybridization
Division of Pediatric Nephrology, University Children s Hospital, University of Heidelberg, Heidelberg, Germany
Nephrol Dial Transplant 26:136-43. 2011
Congenital anomalies of the kidneys and urinary tract (CAKUT) are frequently associated with malformations of other organs.
- HNF1B alterations associated with congenital anomalies of the kidney and urinary tract
Department of Nephrology, National Center for Child Health and Development, Tokyo, Japan
Pediatr Nephrol 25:1073-9. 2010
..factor 1beta (HNF1beta) abnormalities have been recognized to cause congenital anomalies of the kidney and urinary tract (CAKUT), predominantly affecting bilateral renal malformations...
- Contribution of siderophore systems to growth and urinary tract colonization of asymptomatic bacteriuria Escherichia coli
Rebecca E Watts
Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia
Infect Immun 80:333-44. 2012
The molecular mechanisms that define asymptomatic bacteriuria (ABU) Escherichia coli colonization of the human urinary tract remain to be properly elucidated. Here, we utilize ABU E...
- Maternal risk factors for congenital urinary anomalies: results of a population-based case-control study
Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
Urology 78:1156-61. 2011
Epidemiologic data addressing maternal risk factors for congenital urinary tract anomalies (CUTA) are limited, with conflicting results for preexisting diabetes mellitus, gestational diabetes, and tobacco and alcohol use...
- Ontogeny of congenital anomalies of the kidney and urinary tract, CAKUT
Departments of Pediatrics and Medicine, Vanderbilt University Medical Center Nashville, TN, USA
Pediatr Int 45:598-604. 2003
..the Wolffian duct is the first ontogenic misstep that leads to many congenital anomalies of the kidney and urinary tract (CAKUT)...
- A comparison of urinary tract pathology and morbidity in adult populations from endemic and non-endemic zones for urinary schistosomiasis on Unguja Island, Zanzibar
School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
BMC Infect Dis 9:189. 2009
..The aim of this study was to assess the burden of urinary tract pathology and morbidity due to schistosomiasis in Zanzibar and identify reliable clinical predictors of ..
- Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women
Thomas R Hawn
Department of Medicine, University of Washington, Seattle, Washington, USA
PLoS ONE 4:e8300. 2009
..We examined whether candidate gene polymorphisms were associated with altered urine inflammatory profiles in asymptomatic women with or without bacteriuria...
- Vesico-ureteric reflux and urinary tract development in the Pax2 1Neu+/- mouse
Inga J Murawski
Department of Pediatrics, Montreal Children s Hospital, McGill University, Quebec, Canada
Am J Physiol Renal Physiol 293:F1736-45. 2007
Vesico-ureteric reflux (VUR) is a urinary tract abnormality that affects roughly one-third of patients with renal-coloboma syndrome, an autosomal dominant condition caused by a mutation in PAX2...
- The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection
Department of Clinical Microbiology, Microbiology and Tumorbiology Center, Karolinska University Hospital and Karolinska Institutet, SE 171 76 Stockholm, Sweden
Nat Med 12:636-41. 2006
The urinary tract functions in close proximity to the outside environment, yet must remain free of microbial colonization to avoid disease...
- The destruction of the lower urinary tract by ketamine abuse: a new syndrome?
Peggy Sau Kwan Chu
Division of Urology, Department of Surgery, Tuen Mun Hospital, Hong Kong, China
BJU Int 102:1616-22. 2008
..young abusers of street-ketamine (regular recreational abusers of street-ketamine, for its hallucinogenic effects) in Hong Kong, presenting with significant lower urinary tract symptoms (LUTS) but with no evidence of bacterial infection.
- Increased prevalence of renal and urinary tract anomalies in children with congenital hypothyroidism
Division of Pediatric Nephrology, The Children s Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY 10467, USA
J Pediatr 154:263-6. 2009
..We investigated the prevalence of congenital renal and urologic anomalies in children with congenital hypothyroidism to determine whether further renal and urologic investigations would be of benefit...
- Differentiation of epithelial cells in the urinary tract
Medical Faculty, Institute of Cell Biology, Ljubljana, Slovenia
Cell Tissue Res 320:259-68. 2005
Uroplakins, cytokeratins and the apical plasma membrane were studied in the epithelia of mouse urinary tract. In the simple epithelium covering the inner medulla of the renal pelvis, no uroplakins or cytokeratin 20 were detected and ..
- Effects of inhibition of the L-arginine/nitric oxide pathway in the rat lower urinary tract in vivo and in vitro
Department of Clinical Pharmacology, Lund University Hospital, Sweden
Br J Pharmacol 107:178-84. 1992
..to investigate how blockade of the L-arginine/nitric oxide (NO) pathway influences the function of the lower urinary tract in vivo, as studied by cystometry in conscious rats and in vitro, in isolated muscle preparations from the rat ..
- Pathogenic potential of environmental Klebsiella pneumoniae isolates
Department of Gastrointestinal and Parasitic Infections, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
Environ Microbiol 6:584-90. 2004
..K. pneumoniae infections can occur at nearly any body site; however, urinary tract infections and infections of the respiratory tract predominate...
- Roles of serine accumulation and catabolism in the colonization of the murine urinary tract by Escherichia coli CFT073
Andrew T Anfora
Department of Medical Microbiology and Immunology, University of Wisconsin Madison, 1300 University Ave, Room 481 MSC, Madison, WI 53706, USA
Infect Immun 75:5298-304. 2007
..mutant of uropathogenic Escherichia coli strain CFT073 has a hypercolonization phenotype in a murine model of urinary tract infection (UTI) due to increased virulence gene expression by an unknown mechanism (B. J. Haugen et al...
- Physiopathology and etiology of stone formation in the kidney and the urinary tract
Andrew P Evan
Department of Anatomy and Cell Biology, Indiana University School of Medicine, Ms 5055, Indianapolis, IN 46220, USA
Pediatr Nephrol 25:831-41. 2010
- Association of lower urinary tract symptoms and chronic ischaemia of the lower urinary tract in elderly women and men: assessment using colour Doppler ultrasonography
Germar Michael Pinggera
Department of Urology, Medical University of Innsbruck, Austria
BJU Int 102:470-4. 2008
..TRCDUS) whether perfusion of the bladder and prostate is reduced in elderly patients with lower urinary tract symptoms (LUTS), common in later life, as experimental data suggest that chronic ischaemia has a key role in ..
- High urea and creatinine concentrations and urea transporter B in mammalian urinary tract tissues
David A Spector
Division of Renal Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Physiol Renal Physiol 292:F467-74. 2007
Although the mammalian urinary tract is generally held to be solely a transit and storage vehicle for urine made by the kidney, in vivo data suggest reabsorption of urea and other urine constituents across urinary tract epithelia...
- Biofilms and catheter-associated urinary tract infections
Ann Arbor VA Medical Center, Ann Arbor, MI, USA
Infect Dis Clin North Am 17:411-32. 2003
..Future research should focus on additional methods for preventing this common infection...
- Uncomplicated urinary tract infection in adults including uncomplicated pyelonephritis
Lindsay E Nicolle
Departments of Internal Medicine and Medical Microbiology, Health Sciences Centre, University of Manitoba, Winnipeg, MB, Canada
Urol Clin North Am 35:1-12, v. 2008
Acute uncomplicated urinary tract infection and acute pyelonephritis are very common infections affecting many women throughout their lives...
- C-Kit receptor (CD117) in the porcine urinary tract
Department of Pediatric Surgery, University of Leipzig, Leipzig, Germany
Pediatr Surg Int 24:67-76. 2008
..been shown in the genitourinary tract, but systematic studies on the distribution and density of IC within the urinary tract are still lacking...
- Maternal residence near municipal waste incinerators and the risk of urinary tract birth defects
Inserm U625, Universite Rennes I, Campus de Beaulieu, Rennes Cedex, France
Occup Environ Med 67:493-9. 2010
..In a previous ecological study we found an association between the risk of urinary tract birth defects and residence in the vicinity of municipal solid waste incinerators (MSWIs)...
- Increased prevalence of renal and urinary tract anomalies in children with Down syndrome
Juan C Kupferman
Divisions of Pediatric Nephrology and Hypertension, Maimonides Infants and Children s Hospital, Brooklyn, New York 11219, USA
Pediatrics 124:e615-21. 2009
The goal was to investigate the prevalence of renal and urinary tract anomalies (RUTAs) in a Down syndrome (DS) population.
- Pharmacologic perspective on the physiology of the lower urinary tract
Karl Erik Andersson
Department of Clinical Pharmacology, Lund University Hospital, Lund, Sweden
Urology 60:13-20; discussion 20-1. 2002
..However, a selective action on the lower urinary tract may be difficult to obtain...
- Drug Insight: biological effects of botulinum toxin A in the lower urinary tract
Michael B Chancellor
Department of Urology, William Beaumont Hospital in Royal Oak, MI 8073, USA
Nat Clin Pract Urol 5:319-28. 2008
..feedback loops might not only help to explain the mechanism of BTX-A in relieving symptoms of overactive bladder, but also suggest a potential role for BTX-A in the relief of hyperalgesia associated with lower urinary tract disorders.
- Novel genetic aspects of congenital anomalies of kidney and urinary tract
Pediatrics II, University Children s Hospital Essen, Essen, Germany
Curr Opin Pediatr 24:212-8. 2012
Congenital anomalies of the kidney and urinary tract (CAKUT) are among the most frequent organ malformations. They are a relevant cause of chronic renal failure in children...
- Functional analysis of BMP4 mutations identified in pediatric CAKUT patients
Pediatric Nephrology, University of Heidelberg Children s Hospital, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany
Pediatr Nephrol 24:2361-8. 2009
Human congenital anomalies of the kidney and urinary tract (CAKUT) represent the major causes of chronic renal failure (CRF) in children...
- The role of P fimbriae for Escherichia coli establishment and mucosal inflammation in the human urinary tract
Division of Clinical Immunology, Department of Laboratory Medicine, Lund University, Lund, Sweden
Int J Antimicrob Agents 19:522-38. 2002
- Pelvic floor training for lower urinary tract dysfunction in MS
Glasgow Caledonian University, Glasgow, UK
Nurs Times 105:45-7. 2009
The aim of this study was to determine if pelvic floor muscle training (PFMT) improves lower urinary tract function in people with multiple sclerosis (MS)...
- Transcriptome of Proteus mirabilis in the murine urinary tract: virulence and nitrogen assimilation gene expression
Melanie M Pearson
Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
Infect Immun 79:2619-31. 2011
The enteric bacterium Proteus mirabilis is a common cause of complicated urinary tract infections. In this study, microarrays were used to analyze P. mirabilis gene expression in vivo from experimentally infected mice...
- Lithiasis in cystic kidney disease and malformations of the urinary tract
Divisione di Nefrologia, Dipartimento di Scienze Biomediche e Chirurgiche, Universita di Verona, Ospedale Maggiore, P le Stefani 1, 37126, Verona, Italy
Urol Res 34:102-7. 2006
..A proper metabolic evaluation should be conducted to diagnose specific, treatable metabolic disorders, thereby reducing the frequency of recurrent stone disease in these conditions as well...
- Intermediate-term outcomes of robot-assisted laparoscopic nephroureterectomy in upper urinary tract urothelial carcinoma
Sey Kiat Lim
Department of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, South Korea
Clin Genitourin Cancer 11:515-21. 2013
..The purpose of this study was to evaluate the intermediate-term oncological outcomes after (RAL-NU) for UUT-UC...
- Predicting the need for radiologic imaging in adults with febrile urinary tract infection
C van Nieuwkoop
Departments of Infectious Diseases, Leiden University Medical Center, Diaconessenhuis Hospital, Leiden, The Netherlands
Clin Infect Dis 51:1266-72. 2010
Radiologic evaluation of adults with febrile urinary tract infection (UTI) is frequently performed to exclude urological disorders. This study aims to develop a clinical rule predicting need for radiologic imaging.
- Development and differentiation of the ureteric bud into the ureter in the absence of a kidney collecting system
Kevin T Bush
Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0693, and Urological Diseases Research Center, Department of Urology, Children s Hospital, Boston, MA 02115, USA
Dev Biol 298:571-84. 2006
..a lumen lined by cells expressing uroplakin (a protein exclusively expressed in the epithelium of the lower urinary tract)...
- [Gestational diabetes and urinary tract malformations: a hospital case-control study]
Arnaud Fotso Kamdem
Service de Chirurgie Pédiatrique et Orthopédique, Hopital Saint Jacques, Besancon, France
Prog Urol 15:53-8. 2005
b>Urinary tract malformations represent the leading cause of renal failure in children. Gestational diabetes plays a controversial role in the development of urinary tract malformations...
- Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection
Drew J Schwartz
Department of Pediatrics, Molecular Genetics, and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA
Infect Immun 79:4250-9. 2011
b>Urinary tract infections (UTIs) have complex dynamics, with uropathogenic Escherichia coli (UPEC), the major causative agent, capable of colonization from the urethra to the kidneys in both extracellular and intracellular niches while ..
- Alterations in the formation of cyclic nucleotides and prostaglandins in the lower urinary tract of the diabetic rabbit
F H Mumtaz
Department of Urology, Royal Free and University Medical School University College London and The Royal Free Hampstead NHS Trust, UK
Urol Res 27:470-5. 1999
..to forskolin and sodium nitroprusside, respectively, was significantly reduced in the DM tissues of the lower urinary tract compared to the control...
- Urinary tract anomalies and dysfunctional voiding: a spectrum dictated by the influence of amniotic pressure upon fetal urodynamics
F C Tanyel
Department of Pediatric Surgery, Hacettepe University, Institute of Child Health, Ankara, Turkey
Med Hypotheses 54:140-5. 2000
The etiologic basis of urinary tract anomalies and dysfunctional voiding largely remain unknown...
- Extracellular ATP and P2Y receptor activation induce a proinflammatory host response in the human urinary tract
School of Natural Sciences, Linnaeus University, Kalmar, Sweden
Infect Immun 78:3609-15. 2010
..The present study suggests that enhanced ATP release and P2Y receptor activation during urinary tract infection may represent a novel, non-TLR4-mediated mechanism for production of proinflammatory IL-8 in human ..
- Ultrasonographic screening of newborns for congenital anomalies of the kidney and the urinary tracts
Department of Pediatric Nephrology, Turgut Ozal Medical Center, Inonu University, Malatya, Turkey
Urol J 7:161-7. 2010
..To search for the efficiency of scanning the newborns with routine urinary system ultrasonography...
- Proteus mirabilis isolates of different origins do not show correlation with virulence attributes and can colonize the urinary tract of mice
Laboratorio de Microbiologia, Instituto de Investigaciones Biologicas Clemente Estable, Montevideo, Uruguay
Microbiology 152:2149-57. 2006
..has been described as an aetiological agent in a wide range of infections, playing an important role in urinary tract infections (UTIs). In this study, a collection of P...
- Challenges facing renal transplantation in pediatric patients with lower urinary tract dysfunction
Academic Foundation Year Two, London South Thames Deanery, London, United Kingdom
Transplantation 89:1299-1307. 2010
..The commonest cause is a congenital abnormality of the kidneys and urinary tract, often associated with lower urinary tract dysfunction (LUTD)...
- [Recurrent urinary tract infections]
Servicio de Enfermedades Infecciosas, Hospital Universitari Vall d Hebron, Universidad Autonoma, Barcelona, Espana
Enferm Infecc Microbiol Clin 23:28-39. 2005
Recurrent urinary tract infections (RUTI) are a frequent clinical problem in sexually active young women, pregnant or postmenopausal women and in patients with underlying urological abnormalities...
- Diuresis renography for differentiation of upper urinary tract dilatation from obstruction: F+20 and F-15 methods
Department of Urology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
Urol J 4:36-40. 2007
..was to evaluate diuresis renography with an intravenous injection of furosemide 20 minutes after administering the radiopharmaceutical (F+20 protocol) or 15 minutes before (F-15 protocol) in patients with upper urinary tract dilatation.
- Strategies to treat children with end-stage renal dysfunction and severe lower urinary tract anomalies for receiving a kidney transplant
Wlliam C Nahas
Division of Urology, Renal Transplant Unit, University of Sao Paulo, Sao Paulo, Brazil
Pediatr Transplant 13:524-35. 2009
..Patients with severe lower urinary tract abnormalities and ESRD may receive a kidney transplant with comparable success.
- Urinary tract biomaterials
Darren T Beiko
Department of Urology, Queen s University, Kingston, University of Western Ontario, London, Ontario, Canada
J Urol 171:2438-44. 2004
As a result of endourological advances, biomaterials have become increasingly used within the urinary tract. This review article provides an update on the current status of urinary tract biomaterials, discussing issues of ..
- Ultrasound monitoring of structural urinary tract disease in Schistosoma haematobium infection
Charles H King
Division of Geographic Medicine, Case Western Reserve University SOM, Cleveland, Ohio 44106, USA
Mem Inst Oswaldo Cruz 97:149-52. 2002
..Results indicate that urinary tract abnormalities are common (18% overall prevalence) in S...
- Urinary tract infection: one lingering effect of childhood kidney diseases--review of the literature
Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand
J Nephrol 20:21-8. 2007
b>Urinary tract infection (UTI) is a possible warning sign of the presence of anomalies of the urinary tract...
- Unilateral multicystic dysplastic kidney: a meta-analysis of observational studies on the incidence, associated urinary tract malformations and the contralateral kidney
Michiel F Schreuder
Department of Pediatric Nephrology, Radboud University Nijmegen Medical Centre, Amsterdam, The Netherlands
Nephrol Dial Transplant 24:1810-8. 2009
..multicystic dysplastic kidney (MCDK) patients, but show variable results as to the incidence of associated urinary tract abnormalities...
- A molecular and genetic view of human renal and urinary tract malformations
A S Woolf
Nephro Urology Unit, Institute of Child Health, University College London, England, United Kingdom
Kidney Int 58:500-12. 2000
Malformations of the kidney and lower urinary tract are common causes of chronic renal failure in infants and young children, but little is known about the molecular pathogenesis of these disorders...
- Alfuzosin, a selective alpha 1-adrenoceptor antagonist in the lower urinary tract
Department of Biology, Synthelabo Recherche, Bagneux, France
Br J Pharmacol 109:1282-9. 1993
..5. Alfuzosin is a potent selective alpha1-adrenoceptor antagonist in tissues of the lower urinary tract including the human prostate...
- Plasticity in reflex pathways to the lower urinary tract following spinal cord injury
William C de Groat
Department of Pharmacology and Chemical Biology, University of Pittsburgh Medical School, Pittsburgh, PA 15261, USA
Exp Neurol 235:123-32. 2012
The lower urinary tract has two main functions, storage and periodic expulsion of urine, that are regulated by a complex neural control system in the brain and lumbosacral spinal cord...
- Adult care of children from pediatric urology
Christopher R J Woodhouse
Centre for Urology, University College London Hospitals and the Centre for Nephrology, University College London Royal Free Campus, London, United Kingdom
J Urol 187:1164-71. 2012
..We review some abnormalities of the kidneys, progressive renal failure and disorders of bladder function from which general conclusions can be drawn...
- The role of magnetic resonance imaging in pediatric urology
Andrew J Kirsch
Departments of Pediatric Urology, Emory University School of Medicine, Atlanta, Georgia 30342, USA
Curr Opin Urol 16:283-90. 2006
..The aim of this review is to familiarize the reader with the current applications and basic techniques utilizing magnetic resonance imaging in pediatric uroradiology...
- MR urography in children: how we do it
J Damien Grattan-Smith
Department of Radiology, Children s Healthcare of Atlanta, 1001 Johnson Ferry Road, Atlanta, GA 30342, USA
Pediatr Radiol 38:S3-17. 2008
..This paper provides an overview of the practical issues associated with obtaining high-quality scans as well as an introduction into the interpretation of MR urograms...
- Fungal infections of the urinary tract
J D Sobel
Department of Medicine, Detroit Medical Center, Wayne State University School of Medicine, Michigan, USA
World J Urol 17:410-4. 1999
Funguria, fungal urinary tract infections, are most commonly caused by Candida species but may also be caused by Cryptococcus neoformans, Aspergillus species, and the endemic mycoses...