connective tissue

..pathogenesis of chronic low back pain (LBP), there have been no previous studies quantitatively evaluating connective tissue structure in this condition...

..We are concerned that with time the incidence of these pseudotumours may increase. Further investigation is required to define their cause...

..This article presents a new, testable pathophysiological model integrating connective tissue plasticity mechanisms with several well-developed areas of research on cLBP (pain psychology, postural ..

..To identify the structure and composition of the tree shrew optic nerve to determine its potential as a model for glaucoma...

..In the present study, the immunolocalization and mRNA expression of connective tissue growth factor (CTGF) in muscles from normal and dystrophic human muscles were examined with the goal of ..

..This study assesses for the presence and localization of connective tissue growth factor (CTGF) in drug-induced gingival overgrowth tissues...

..exhibited a much broader expression pattern than previously thought: it was ubiquitously expressed in the connective tissue sheaths (fascia) that encase the tissues and organs of the body...

Irreversible connective tissue proliferation in muscle is a pathological hallmark of Duchenne muscular dystrophy (DMD), a genetic degenerative muscle disease due to lack of the sarcolemmal protein dystrophin...

The purpose of this study was to compare the biocompatibility of amalgam, gray MTA and white MTA in the connective tissue of rats. We used 45 Sprague-Dawley rats in this study. The rats were divided into three groups...

To investigate pathologic fibrosis and connective tissue matrix in left ventricular hypertrophy due to chronic arterial hypertension in humans.

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The purpose of this study was to evaluate the subcutaneous connective tissue reactions to ProRoot, mineral trioxide aggregate (MTA; Dentsply), and Oralloy, high-copper amalgam (Coltene)...

..antibodies, which may suggest differences in pathogenesis, were different in basaloid hyperplasia overlying connective tissue/mesenchymal hamartomas and BCC...

BACKGROUND: The clinical outcome of connective tissue grafts in the treatment of gingival recessions has been documented in numerous studies...

The purpose of this paper was to study the reaction of rat subcutaneous connective tissue to the implantation of dentin tubes filled with white mineral trioxide aggregate (MTA), a material that will be marketed...

We examined the epithelial surface and connective tissue cores (CTCs) of each lingual papilla on the Paenungulata, Cape hyrax (Procavia capensis), by scanning electron microscopy and light microscopy...

..The correlation between procollagen-III-N-propeptide and TGF-beta1 emphasizes its role in hepatic fibrogenesis...

..muscles are able to maintain the concentrations of the general protein pools and the main contractile and connective tissue elements...

..The possibility that dietary ingestion of curcumin may have a beneficial effect in degenerative aortic aneurysms warrants further consideration...

The aim of the study was to evaluate the short-term and 1-year follow-up results of connective tissue manipulation and combined ultrasound (US) therapy (US and high-voltage pulsed galvanic stimulation) in terms of pain, complaint of ..

..The observed biophysics seems to indicate that cell-cell and cell-matrix interactions play a major role in ice propagation in TEs...

The arrangement of connective tissue components (i.e...

b>Connective tissue growth factor (CTGF) has been proposed to play a key role in the pathogenesis of hepatic fibrosis in biliary atresia (BA)...

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..The results of this study merit the further investigation of the role of reactive oxidative species with regard to Nfkappab1 in the copper deficient rat heart...

..This information will be fundamental in understanding what holds collagenous tissues together at the fibrillar level, and could have important implications for people with Ehlers-Danlos syndrome...

Because of its distinctive clinical features and histopathological characteristics, zosteriform connective tissue nevus is considered a separate entity from other connective tissue nevi...

..CONCLUSIONS: These serum fibrotic markers, especially the serum HA test, would be clinically useful for assessing staging and grading in patients with chronic hepatitis C...

..Thus, laser photobiomodulation was able to induce several modifications during the cutaneous healing process, especially in favoring newly-formed collagen fibers to be better organized and compactedly disposed...

The dermis of sea cucumbers is a catch connective tissue or mutable collagenous tissue that shows large changes in stiffness...

..Although PLGA-based hybrid scaffolds have earlier been proposed for dense connective tissue engineering, rapid biodegradation of PLGA was a drawback...

Muscle and its connective tissue are intimately linked in the embryo and in the adult, suggesting that interactions between these tissues are crucial for their development...

..Often in skeletal muscle research, immunostaining with antibodies against connective tissue or plasma membrane proteins (collagen 1, laminin, and caveolin 3) are used for this purpose...

..An anatomic study of the posterior midline structures of the cervical spine was performed using a new sheet-plastination (E12) technique in conjunction with gross anatomic dissection...

The visco-elastic behavior of connective tissue is generally attributed to the material properties of the extracellular matrix rather than cellular activity...

..Future studies are needed to investigate the importance of intermuscular force transmission during movement in health and disease...

..The aim of this study was to assess whether levels of a type V collagen fragment, the propeptide CO5-1230, indicate the amount of collagen deposited during liver fibrosis...

..Zinc (Zn) is an essential trace element and it is abundant in connective tissues, however biological roles of Zn and its transporters in those tissues and cells remain unknown...

..a unique wound healing response following spinal cord injury in which the lesion site fills in with a connective tissue matrix...

..a) after full longitudinal compartmental fasciotomy, and (b) after blunt dissection of the intermuscular connective tissue linkages between EDL and TA+EHL...

..Six 1 and Six 2 also are expressed in skeletal and smooth muscle, respectively. These genes may participate in the patterning of the distal tendons of the limb phalanges by setting positional values along the limb axes...

..a possible anabolic effect on myofibrillar muscle protein, we suggest a role for GH as an anabolic agent in connective tissue in human skeletal muscle and tendon...

..In this report, we characterize the morphology and processes that influence the development of nipple connective tissue. The connective tissue of the nipple displayed increased levels of proteoglycans, and collagen bundles with ..

This clinical report describes the use of a subepithelial connective tissue graft to recontour a soft tissue margin discrepancy for a single-implant crown in the anterior maxilla...

..The local increased collagen synthesis was preceded by an elevation of local concentration of IGFBP-4, suggesting that IGFBP-4 may have a key role in the IGF-axis effect on the human collagen synthesis in vivo...

..found in patients suffering premature thrombosis and homocystinuric levels of Hcy but lacking any of the connective tissue disorders typical of homocystinuria due to CBS deficiency...

..The results provide important new information on the changes to the expression of CS GAG chains during disease and development...

..The aim of this study was to compare the clinical results of 2 BTs by autogenous connective tissue (CT) or ADM. METHODS: In 30 systemically healthy, non-smoking patients aged 34.5 +/- 5...

Acellular dermal matrix allograft (ADMA) has successfully been applied as a substitute for free connective tissue grafts (CTG) in various periodontal procedures, including root coverage...

..CONCLUSIONS: Visual acuities remained stable or improved over a 12-month period after posterior subtenon triamcinolone injections for refractory DME. There was a statistically significant improvement in visual acuity at 1 month...

..This case report describes the use of a subepithelial connective tissue graft (SCTG) on a resin ionomer-restored root surface to treat gingival recession that is complicated with ..

..compare the results of vitrectomy with or without arteriovenous (AV) crossing sheathotomy for macular edema associated with branch retinal vein occlusion (BRVO)...

..In TSC associated kidney tumors and sporadic brain tumors the loss/reduction of tuberin has been shown...

..To reconstruct a hard connective tissue using the silk sheet and type-I collagen as the scaffold for fibroblasts, three different three-dimensional ..

..electron microscopic study of cellular interrelations in the process of capillary growth in the regenerating connective tissue. The study was performed in 28 albino rats which have been implanted with different polymer nets in the ..

..of the skin to tensile forces and describes the adaptive phenotype of fibroblasts residing in the dermal connective tissue. Work from a number of different groups suggests that tension induces in these cells many biological ..

Acupuncture needle manipulation has been previously shown to result in measurable changes in connective tissue architecture in animal experiments...

A morphologic study of connective tissue structures in clubfoot, with special emphasis on the presence of myofibroblasts, was undertaken to investigate the theory of retracting fibrosis as an etiologic factor...

..The results demonstrate that vascular adventitial fibroblasts are able to synthesize and release ET-1 in response to ANG II...

..Sensory evaluation showed improvement (P<0.0009) for tenderness and connective tissue component and all except ginger had a lower shear force than the control (P<0.003)...

Fibrillin, a connective tissue macromolecule (Mr = 350,000) which is normally insoluble in its tissue form, has been purified from the medium of human skin fibroblast and ligament cells in culture...

Unspecialized "loose" connective tissue forms an anatomical network throughout the body. This paper presents the hypothesis that, in addition, connective tissue functions as a body-wide mechanosensitive signaling network...

..The aim of this study is to compare the ADMA with the conventional subepithelial connective tissue graft (SCTG) in the treatment of gingival recession."

..In comparison to triangular and diamond tips, a bevel tip causes more needle bending and is more easily affected by tissue density variations. Forces for larger diameter needles are higher due to increased cutting and friction forces...

..The observed negative storage moduli are predicted by the new model when the relaxation time of the material is large and the working frequency is high. The model is fitted to experimental data to obtain values for material constants...

..The results show the excellent performance of our method. The accuracy of the estimation is better than 15%, and the reproducibility of the deformation is better than 0.4 mm even for an FE analysis with different boundary condition...

..The estimated material coefficients varied with test location and subject indicating that these coefficients cannot be readily extrapolated to other sites or individuals...

..Model predictions are in good agreement with experimental observations for mitral-valve chordae tendinece...

..It is also argued that this microplane formulation could be modified or extended to model many other phenomena of interest in biomechanics...

..CONCLUSION: In the early and intermediate stages of cystic growth, osmotic pressure differences play an important role; however, in very large cysts, this role becomes negligible, and cell birth in the lining dominates growth...

..Osmotic pressure in the ECM is found to contribute significantly to the viscoelastic characteristics of soft tissues during their deformation...

..In order to validate the proposed approach, unconfined compressive tests of rubber have been performed...

..The system was built and validated using phantom experiments...

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..Since the discrete material node point forces typically point in the direction of potential material deposition, they can be interpreted as a driving force for the healing mechanism...

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..The combined influences of out-of-plane diffraction, beam shape, and shear viscosity on the shape of transient waves are carefully studied as they represent a major issue in ultrasound-based viscoelasticity imaging techniques...

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..8 mm). The model predictions are consistent with the published experimental observations...

..The purpose of this meta-analysis was to compare the efficacy of ADM-based root coverage (RC) and ADM-based increase in keratinized tissues to other commonly used mucogingival surgeries...

..This concept is used in conjunction with a potential-field-based path planning technique to demonstrate needle tip placement and obstacle avoidance. Results from open loop insertion experiments are provided...

..Relationship between Meff and knee angle provides insights into how changes in posture moderate impact transients at different gaits...

..A real-time and realisti finite-element simulation of viscoelastic tissue behavior using experimental data collected by a robotic indenter offers one solution...

..Future work on these models includes incorporation of viscous material properties and modeling the ultrasonic tracking of displaced scatterers...

..Jitter and bias associated with the ultrasonic displacement tracking also impact the estimation of a tissue's dynamic response to acoustic radiation force excitation...

..The present analysis provided a theoretical explanation, from a biomechanical point-of-view, for the inconsistencies in the published experimental data for the biodynamic responses of fingerpad...

..We propose thumbrules to estimate the correlation between the two models for specific problems...

..Peak bone stress was found at the third metatarsal in all calculated cases with a minimal increase of about 7% with soft tissue stiffening...

..The selection of a model system (connective tissue) is described along with a corresponding gelatin-based system in which the make-up of the material can be &..

..Thus, the data demonstrate that the structural properties of the foot can vary across regions, but careful consideration must be given to the applied loads and the manner in which the loads were applied...

..This method is promising for improving the fitting of prostheses in the clinical setting and for protecting the residual limb from pressure ulcers and DTI...

..Moreover, glycerol protects cleared tissue by increasing its thermal stability and minimizing thermal alterations of mechanical properties...

..The maximum signal-to-noise ratio is 3 times as high as that of the CC method, showing higher sensitivity as well. The method is computationally efficient, achieving 0.7 msec/RF line on a standard personal computer...

..Therefore, this method for normalizing stress data was proposed for future studies of incremental stress-relaxation, or whenever comparing stress-relaxation at different strains...

..The aspiration method is validated experimentally with a synthetic material. In vivo (intra-operatively during surgical interventions) and ex vivo experiments were performed on human uteri...

..The model predictions for one-dimensional tissue shrinkage and the corresponding mechanical property degradation agreed well with the experimental data, showing that the gross tissue behavior is dictated by molecular-level phenomena...

..In a research experiment involving 10 surgeons, the system's tissue discriminatory power was three times more sensitive, and 10% less specific than surgeon's hand...

..g., magnetic resonance, computed tomography, ultrasound. etc) that have sufficient anatomically-based intensity heterogeneity and remain consistent from a pre- to a post-deformed state could be used in this paradigm...

..The method is simple and accurate and is believed to be generally useful for anyone who wishes to model biologic membranes with an experimentally driven strain-energy function...

The matrix metalloproteinases (MMPs) are a group of zinc enzymes secreted from connective tissue cells and phagocytes...

Scleroderma is a progressive, potentially life-threatening disease of the connective tissue that can cause hardening of the skin, and damage to lungs, heart, kidney, and gastrointestinal tract, The disease may also affect blood vessels, ..

..have been reported between prolapse, joint hypermobility and abdominal striac suggesting a generalized connective tissue defect affecting pelvic organ support, joints and skin. One explanation is a defect in collagen biosynthesis...

..Type I-IV) classes and the three more recent (Type V-VII) novel OI categories demonstrate various skeletal, connective tissue, and neuromuscular manifestations...

..According to this hypothesis, the amount of connective tissue in the lung is increased when Pc is elevated for several days...

..According to this hypothesis, the amount of connective tissue in the lung is increased when Pc is elevated for several days...

The long-term goal of the proposed research is to understand molecular basis and functional impact of skin connective tissue aging. Skin, like all human organs, undergoes deleterious alterations as a consequence of the passage of time...

The long-term goal of the proposed research is to understand molecular basis and functional impact of skin connective tissue aging. Skin, like all human organs, undergoes deleterious alterations as a consequence of the passage of time...

..All of these features are attributable, at least in part, to impairment of the structural integrity of skin connective tissue. The structural component of skin connective tissue is the dermal extracellular matrix (ECM), which is ..

..is largely caused by irreversible destruction of fibrillar collagen, the major structural protein in skin connective tissue (dermis)...

..is largely caused by irreversible destruction of fibrillar collagen, the major structural protein in skin connective tissue (dermis)...

..is largely caused by irreversible destruction of fibrillar collagen, the major structural protein in skin connective tissue (dermis)...

..Now, robust evidence linking connective tissue to acupuncture structures has changed the research landscape and offers a new testable hypothesis: ..

..Long-term exposure to UV irradiation damages human skin connective tissue and promotes formation of skin cancer, the most common form of human cancer...

..project is to establish the usefulness of needle torque measurements for the diagnosis and monitoring of connective tissue pathology associated with chronic musculoskeletal conditions treated by manual therapies...

Cardiac valve thickening is a major cardiovascular manifestation of connective tissue disorders (e.g., Marfan syndrome (MFS) and Ehlers-Danlos syndrome (EDS)), and non-syndromic valvular diseases...

Cardiac valve thickening is a major cardiovascular manifestation of connective tissue disorders (e.g., Marfan syndrome (MFS) and Ehlers-Danlos syndrome (EDS)), and non-syndromic valvular diseases...

Proteochondroitin sulfate is a major structural constituent of connective tissue, and occurs as an ubiquitous component of cell surface, where it is considered to be involved in specific cell-cell, cell-matrix and cell-receptor functions...

..Recent evidence suggests that the connective tissue in the vicinity of an acupuncture point plays a critical role in the local tissue response to in vivo ..

Ultraviolet (UV) irradiation from the sun damages human skin connective tissue and causes premature skin aging (photoaging). Photoaging exists in nearly all adult individuals and is therefore a significant public health concern...

The mucopolysaccharidoses (MPS) are inherited, connective tissue disorders that result from the deficient activities of specific lysosomal enzymes required for glycosaminoglycan (GAG) degradation...

Ultraviolet (UV) irradiation from the sun damages human skin connective tissue and causes premature skin aging (photoaging). Photoaging exists in nearly all adult individuals and is therefore a significant public health concern...

..model in which an inflammatory microenvironment caused by soft tissue injury mobilizes resident Tie2+ connective tissue progenitor cells of vascular origin...

..model in which an inflammatory microenvironment caused by soft tissue injury mobilizes resident Tie2+ connective tissue progenitor cells of vascular origin...