ear ossicles

Summary

Top Publications

  1. ncbi Ontogenetic and phylogenetic transformations of the ear ossicles in marsupial mammals
    Marcelo R SAnchez-Villagra
    Zoologisches Institut, Spezielle Zoologie, Universitat Tubingen, Auf der Morgenstelle 28, D 72076 Tubingen, Germany
    J Morphol 251:219-38. 2002
  2. ncbi Hystology findings' correlation between the ossicular chain in the transoperative and cholesteatomas
    Cristina Dornelles
    Brazilian Center for Otitis Media
    Braz J Otorhinolaryngol 73:738-43. 2007
  3. ncbi Effect of ossicular prosthesis biofilms on middle ear scarring and hearing outcomes
    Eric M Jaryszak
    Department of Otolaryngology Head and Neck Surgery, University of Florida College of Medicine, Gainesville, Florida, USA
    Otol Neurotol 30:1191-5. 2009
  4. ncbi Biofilm formation by Pseudomonas aeruginosa on ossicular reconstruction prostheses
    Eric M Jaryszak
    Department of Otolaryngology Head and Neck Surgery, University of Florida College of Medicine, Gainesville, FL 32610 0264, USA
    Am J Otolaryngol 30:367-70. 2009
  5. ncbi Probabilities of ossicular discontinuity in chronic suppurative otitis media using pure-tone audiometry
    Ryner Jose C Carrillo
    Department of Anatomy, Philippine General Hospital, Ermita, Manila, Philippines
    Otol Neurotol 28:1034-7. 2007
  6. ncbi Mass distribution and rotational inertia of "microtype" and "freely mobile" middle ear ossicles in rodents
    Danielle Lavender
    University of Cambridge, Department of Physiology, Development and Neuroscience, Downing Street, Cambridge CB2 3EG, UK
    Hear Res 282:97-107. 2011
  7. ncbi Relationship of preoperative findings and ossicular discontinuity in chronic otitis media
    Fuh Cherng Jeng
    Department of Otolaryngology, China Medical College Hospital, Taichung, ROC
    Otol Neurotol 24:29-32. 2003
  8. ncbi Paraganglioma presenting as chronic otitis media with cholesteatoma: pitfalls and strategies
    Jui Lin Hsu
    Department of Otolaryngology, Chang Gung University, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Japan
    Am J Otolaryngol 25:190-4. 2004
  9. ncbi [Post-traumatic cholesteatoma of temporal bone]
    Jerzy Kuczkowski
    Katedra i Klinika Chorób Uszu, Nosa, Gardła i Krtani AM w Gdańsku
    Otolaryngol Pol 61:207-10. 2007
  10. pmc Non-ossicular signal transmission in human middle ears: Experimental assessment of the "acoustic route" with perforated tympanic membranes
    Susan E Voss
    Picker Engineering Program, Smith College, 51 College Lane, Northampton, Massachusetts 01063, USA
    J Acoust Soc Am 122:2135-53. 2007

Research Grants

Detail Information

Publications215 found, 100 shown here

  1. ncbi Ontogenetic and phylogenetic transformations of the ear ossicles in marsupial mammals
    Marcelo R SAnchez-Villagra
    Zoologisches Institut, Spezielle Zoologie, Universitat Tubingen, Auf der Morgenstelle 28, D 72076 Tubingen, Germany
    J Morphol 251:219-38. 2002
    ..skulls representing a wide range of taxa and aims at addressing several issues concerning the evolution of the ear ossicles in marsupials...
  2. ncbi Hystology findings' correlation between the ossicular chain in the transoperative and cholesteatomas
    Cristina Dornelles
    Brazilian Center for Otitis Media
    Braz J Otorhinolaryngol 73:738-43. 2007
    ..Chronic otitis media is hystopathologycaly defined as the presence of irreversible inflammatory tissue changes in the middle ear. Ossicular lesions represent the most prevalent change...
  3. ncbi Effect of ossicular prosthesis biofilms on middle ear scarring and hearing outcomes
    Eric M Jaryszak
    Department of Otolaryngology Head and Neck Surgery, University of Florida College of Medicine, Gainesville, Florida, USA
    Otol Neurotol 30:1191-5. 2009
    ..The purpose of this study was to determine if biofilms are present on ORPs in patients undergoing revision ossicular chain reconstruction and if their presence correlates with middle ear scarring or hearing outcomes...
  4. ncbi Biofilm formation by Pseudomonas aeruginosa on ossicular reconstruction prostheses
    Eric M Jaryszak
    Department of Otolaryngology Head and Neck Surgery, University of Florida College of Medicine, Gainesville, FL 32610 0264, USA
    Am J Otolaryngol 30:367-70. 2009
    ..The purpose of this experiment was to determine if PA forms biofilm on different ossicular chain reconstruction prostheses to a different degree...
  5. ncbi Probabilities of ossicular discontinuity in chronic suppurative otitis media using pure-tone audiometry
    Ryner Jose C Carrillo
    Department of Anatomy, Philippine General Hospital, Ermita, Manila, Philippines
    Otol Neurotol 28:1034-7. 2007
    ..To analyze the likelihood ratios (LRs) and predictive values of preoperative air-bone gap (ABG) levels on the presence of gross ossicular discontinuity (OD) among chronic suppurative otitis media (CSOM) patients...
  6. ncbi Mass distribution and rotational inertia of "microtype" and "freely mobile" middle ear ossicles in rodents
    Danielle Lavender
    University of Cambridge, Department of Physiology, Development and Neuroscience, Downing Street, Cambridge CB2 3EG, UK
    Hear Res 282:97-107. 2011
    ..Functional differences appear to exist even among rodent ears of the same general type, but the adaptive significance of these differences remains enigmatic...
  7. ncbi Relationship of preoperative findings and ossicular discontinuity in chronic otitis media
    Fuh Cherng Jeng
    Department of Otolaryngology, China Medical College Hospital, Taichung, ROC
    Otol Neurotol 24:29-32. 2003
    ..If preoperative information can be used to determine whether or not the ossicular chain is intact, the patient can be better informed and the surgeon can be better prepared before surgery...
  8. ncbi Paraganglioma presenting as chronic otitis media with cholesteatoma: pitfalls and strategies
    Jui Lin Hsu
    Department of Otolaryngology, Chang Gung University, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Japan
    Am J Otolaryngol 25:190-4. 2004
    ..The patient underwent postauricular tympanomastoidectomy with extended facial recess approach to remove the tumor. No evidence of recurrence and complications were noted...
  9. ncbi [Post-traumatic cholesteatoma of temporal bone]
    Jerzy Kuczkowski
    Katedra i Klinika Chorób Uszu, Nosa, Gardła i Krtani AM w Gdańsku
    Otolaryngol Pol 61:207-10. 2007
    ..We recomend long term follow-up in any patient with longitudinal temporal bone fracture with CT for any new otologic complaints...
  10. pmc Non-ossicular signal transmission in human middle ears: Experimental assessment of the "acoustic route" with perforated tympanic membranes
    Susan E Voss
    Picker Engineering Program, Smith College, 51 College Lane, Northampton, Massachusetts 01063, USA
    J Acoust Soc Am 122:2135-53. 2007
    ..Some features of the frequency dependence of H(P(CAV) ) and H(WPD) can be interpreted in terms of a structure-based lumped-element acoustic model of the perforation and middle-ear cavities...
  11. ncbi Ossicular fixation caused by bone dust after saccus decompression surgery
    P Martinez Devesa
    Royal National Throat, Nose and Ear Hospital, London, UK
    Otol Neurotol 23:949-51; discussion 951-2. 2002
    ..To highlight the clinical and histologic features of ossicular fixation produced by bone dust during mastoid surgery...
  12. ncbi Cartilage ossiculoplasty by lever method
    Hideo Yamane
    Department of Otolaryngology and Head and Neck Surgery, Osaka City University Graduate School, Osaka, Japan
    Acta Otolaryngol 128:744-9. 2008
    ..Postoperative air-bone gaps (ABGs) followed up for 2.1-3.2 years gave satisfactory improvement audiometrically compared with former reports...
  13. ncbi Improvements to staged canal wall up tympanoplasty for middle ear cholesteatoma
    Yasuyuki Hinohira
    Department of Otolaryngology, Takanoko Hospital, Ehime, Japan
    Otolaryngol Head Neck Surg 137:913-7. 2007
    ..To describe our improvements to staged canal wall up tympanoplasty with mastoidectomy (SCUT) for middle ear cholesteatoma, and to show more successful outcomes of the surgery compared with our data previously reported...
  14. ncbi Hearing results for ossicular reconstruction using a cartilage-connecting hydroxyapatite prosthesis with a spearhead
    Tadashi Doi
    The Department of Otolaryngology, Kansai Medical University, Hirakata, Osaka, Japan
    Otol Neurotol 28:1041-4. 2007
    ..Assessment of the efficacy of ossicular reconstruction using a cartilage-connecting hydroxyapatite prosthesis designed with a spearhead to reduce extrusion and dislocation of the implant...
  15. ncbi Traumatic ossicular dislocations: etiology and management
    Sertac Yetiser
    Department of ORL and HNS, Gulhane Medical School, Etlik, Ankara, Turkey
    Am J Otolaryngol 29:31-6. 2008
    ..This study was conducted to discuss the etiologic factors, clinical-radiologic findings, and surgical outcomes in patients with traumatic ossicular pathology...
  16. ncbi To POP or not: ossiculoplasty in congenital aural atresia surgery
    Eric J Dobratz
    Department of Otolaryngology Head and Neck Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Laryngoscope 118:1452-7. 2008
    ..To examine indications for ossiculoplasty (OP) in aural atresia surgery and to compare audiometric results and surgical revision rates between patients undergoing OP and those undergoing intact native chain reconstruction (INCR)...
  17. ncbi [Tympanic-ossicular reconstruction. Functional results using cartilage palisades and titanium prostheses]
    L M Menéndez-Colino
    Servicio de ORL y Patología cérvico facial, Hospital Clinico de Barcelona
    Acta Otorrinolaringol Esp 53:718-24. 2002
    ..Seven out of sixteen canal wall down (43.7%) and three out seven canal wall up (42.9%) had a postoperative air-bone gap between 0 and 10 dB...
  18. ncbi Prognostic factors in ossiculoplasty
    Caroline De Vos
    ENT Department, University Hospital Saint Luc, Brussels, Belgium
    Otol Neurotol 28:61-7. 2007
    ..To analyze predictive factors of outcome after ossiculoplasty using a standard ossicular prosthesis system...
  19. ncbi A new double-cartilage block ossiculoplasty: long-term results
    Giuseppe Malafronte
    Department of Otolaryngology, Head and Neck Surgery, Azienda Ospedaliera G Moscati, Avellino, Italy
    Otol Neurotol 29:531-3. 2008
    ....
  20. ncbi [Imaging in adult chronic otitis]
    M T Williams
    Service d Imagerie Medicale, Fondation Ophtalmologique Adolphe de Rothschild, 25 29, rue Manin, 75940 Paris Cedex 19, France
    J Radiol 87:1743-55. 2006
    ..The objective of this paper is to specify the indications, the results and the limits of pre- and postoperative imaging in COM...
  21. ncbi Aggressiveness and quantification of epithelial proliferation of middle ear cholesteatoma by MIB1
    Y Mallet
    Departments of Otorhinolaryngology, centre hospitalier universitaire Lille, Lille, France
    Laryngoscope 113:328-31. 2003
    ..To assess an easy method that predicts cholesteatoma aggressiveness...
  22. ncbi [Operative therapy of the adhesive otitis media]
    Li sheng Yu
    Department of Otorhinolaryngology, People s Hospital of Peking University, Beijing, 100044, China
    Zhonghua Er Bi Yan Hou Ke Za Zhi 39:40-3. 2004
    ..To study the operative indications and treatment for adhesive otitis media (AOM)...
  23. ncbi U.S. Phase I preliminary results of use of the Otologics MET Fully-Implantable Ossicular Stimulator
    Herman A Jenkins
    University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Otolaryngol Head Neck Surg 137:206-12. 2007
    ..The safety of the Otologics Fully-Implantable MET Ossicular Stimulator was assessed in adult patients with bilateral moderate to severe sensorineural hearing loss...
  24. ncbi Otologics Middle Ear Transducer Ossicular Stimulator: performance results with varying degrees of sensorineural hearing loss
    Herman A Jenkins
    University of Colorado Health Sciences Center, Denver, CO 80202, USA
    Acta Otolaryngol 124:391-4. 2004
    ....
  25. ncbi [Application of hydroxyapatite in micro-otosurgery: experiment with guinea pigs and clinical application]
    Yang Liu
    Department of Otolaryngology, Navy General Hospital, Beijing 100037, China
    Zhonghua Yi Xue Za Zhi 86:45-7. 2006
    ..To investigate the feasibility of hydroxyapatite (HA) middle ear prostheses in otosurgery...
  26. ncbi Preoperative evaluation of ossicular chain abnormality in patients with conductive deafness without perforation of the tympanic membrane
    Keiji Tabuchi
    Department of Otolaryngology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan
    Arch Otolaryngol Head Neck Surg 131:686-9. 2005
    ..To evaluate the usefulness of pure-tone audiometry, tympanometry, and liquid and acoustic reflex (AR) tests in the differential diagnosis of ossicular fixation and discontinuity...
  27. ncbi Ossiculoplasty with intact stapes and absent malleus: the silastic banding technique
    Robert Vincent
    Jean Causse Ear Clinic, Traverse de Béziers, Colombiers, France
    Otol Neurotol 26:846-52. 2005
    ..Ossiculoplasty is performed with a total ossicular replacement prosthesis positioned from the stapes footplate to the under-surface of the tympanic membrane, using a Silastic banding technique to stabilize the prosthesis...
  28. ncbi Value of digital volume tomography in patients with conductive hearing loss
    C V Dalchow
    Department of Otolaryngology and Head and Neck Surgery, Philipps University of Marburg, Deutschhausstr 3, 35037, Marburg, Germany marburg de
    Eur Arch Otorhinolaryngol 263:92-9. 2006
    ..Digital volume tomography delivers a small radiation dose with a high resolution and a low purchase price for the equipment...
  29. ncbi Bone-conducted sound: physiological and clinical aspects
    Stefan Stenfelt
    Department of Otolaryngology Head and Neck Surgery, Stanford University Medical Center, Stanford, California 94305 5739, USA
    Otol Neurotol 26:1245-61. 2005
    ..Knowledge of the physiology, clinical aspects, and limitations of bone conduction sound is important for clinicians dealing with hearing loss and is the purpose of this review...
  30. ncbi [Revision ossiculoplasty: anatomical and functional results]
    M Folia
    Hopital Edouard Herriot, Service d ORL et de Chirurgie Cervico Faciale et d Audiophonologie, Lyon, France
    Rev Laryngol Otol Rhinol (Bord) 127:121-5. 2006
    ..To analyse the anatomical and functional results after second-look ossiculoplasty using Titanium (TI) and Hydroxyapatite (HA) prosthesis and to study the prognostic factors for good functional results...
  31. ncbi Reconstruction of the tensor tympani tendon
    M Bauer
    Department of Otorhinolaryngology and Head and Neck Surgery, University of Pecs, Pecs, Hungary
    J Laryngol Otol 120:240-3. 2006
    ..The pre-operative 55.0 dB air-bone gap decreased immediately to 3.3 dB, widening after three years to 15.0 dB...
  32. ncbi Predictive role of Carhart's notch in pre-operative assessment for middle-ear surgery
    H Yasan
    Ear Nose and Throat Head and Neck Surgery Department, School of Medicine, Suleyman Demirel University, Isparta, Turkey
    J Laryngol Otol 121:219-21. 2007
    ..To evaluate the predictive role of the audiometric Carhart's notch for the assessment of middle-ear pathology prior to surgical intervention...
  33. ncbi Bone cement ossiculoplasty: incus to stapes versus malleus to stapes cement bridge
    Yildirim A Bayazit
    Department of Otolaryngology, Faculty of Medicine, University of Gaziantep, Turkey
    Otol Neurotol 26:364-7. 2005
    ..In this study, our purpose was to evaluate results of our experience with bone cement repair of ossicular discontinuity between the incus and stapes and between the malleus and stapes...
  34. ncbi Use of Mimix hydroxyapatite bone cement for difficult ossicular reconstruction
    Joel A Goebel
    Department of Otolaryngology Head and Neck Surgery, Washington University in St Louis, 660 S Euclid, Campus Box 8115, St Louis, MO 63110, USA
    Otolaryngol Head Neck Surg 132:727-34. 2005
    ..To describe the advantages of using Mimix hydroxyapatite (HA) bone cement in reconstructing a variety of ossicular chain abnormalities...
  35. ncbi Type III cartilage "shield" tympanoplasty: an effective procedure for hearing improvement
    Efthymios Kyrodimos
    Department of Otolaryngology Head and Neck Surgery, Virginia Commonwealth University Medical Center, Richmond, VA, USA
    Otolaryngol Head Neck Surg 136:982-5. 2007
    ..To report the hearing results following type III cartilage "shield" tympanoplasty...
  36. ncbi Allograft tympanoplasty
    T Somers
    University ENT Department, Sint Augustinus Hospital, Wilrijk Antwerp, Belgium
    Acta Otorhinolaryngol Belg 58:87-96. 2004
    ..The authors believe that the tympano-ossicular allograft is the material of choice in extensively diseased middle ears destroyed by chronic otitis media with or without cholesteatoma...
  37. ncbi A new L-shaped titanium prosthesis for total reconstruction of the ossicular chain
    Ugo Fisch
    ORL Center, Klinik Hirslanden, Zurich
    Otol Neurotol 25:891-902. 2004
    ..To describe the technique used for total ossiculoplasty with the Fisch titanium total prosthesis and evaluate the 1-year postoperative functional results in patients presenting with the stapes (or footplate) without the malleus handle...
  38. ncbi Hydroxyapatite versus titanium ossiculoplasty
    Eric Truy
    Department of Otolaryngology, Head and Neck Surgery and Phoniatrics, Edouard Herriot Hospital, Lyon, France
    Otol Neurotol 28:492-8. 2007
    ..To compare the results of ossicular chain reconstruction using hydroxyapatite (HA) and titanium (TI) prostheses...
  39. ncbi Initial experiments to develop a MEMS transducer for a new implantable audioprosthesis to substitute the tympanic-ossicular system
    Rafael Urquiza de la Rosa
    Department of Otolaryngology, University of Malaga, Malaga, Spain
    Acta Otolaryngol 127:389-94. 2007
    ....
  40. ncbi Intraoperative ossicular loading with the Otologics fully implantable hearing device
    Herman A Jenkins
    Department of Otolaryngology, University of Colorado, Denver, CO, USA
    Acta Otolaryngol 127:360-4. 2007
    ....
  41. ncbi Applicability of autologous incus: the influence of age and localization of cholesteatoma
    Milan Stankovic
    ORL Clinic, Bul Z Djindjica 52, 18 000, Nis, Serbia
    Eur Arch Otorhinolaryngol 264:995-8. 2007
    ..Defects of long process with external osteitis of incudes and more intense pathological changes demand their removal and use of other reconstructive materials for tympanoplasties in order to avoid tympanoplasty failure...
  42. ncbi [Analysis of preoperative findings and ossicular condition in chronic suppurative otitis media]
    Hongyun Feng
    Department of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan, 250012, China
    Lin Chuang Er Bi Yan Hou Ke Za Zhi 19:7-8, 11. 2005
    ..To discussion the relationship of preoperative findings and ossicular condition in chronic suppurative otitis media...
  43. ncbi Should ossicular reconstruction be staged following tympanomastoidectomy
    Harold H Kim
    Wilson Ear Clinic, Portland, Oregon 97209, USA
    Laryngoscope 116:47-51. 2006
    ..To determine whether ossicular reconstruction (OCR) performed concurrent with tympanomastoidectomy for cholesteatoma results in significantly different hearing results when compared to OCR performed in a separate, staged procedure...
  44. ncbi Cathepsin L activity and its inhibitor in human otitis media
    T Kusunoki
    Department of Otolaryngology, Kinki University School of Medicine, Osakasayama, Osaka, Japan
    J Otolaryngol 30:157-61. 2001
    ..The relationships of our findings to clinical findings (e.g., grade of bone destruction) were also studied...
  45. ncbi Laser stapedotomy minus prosthesis (laser STAMP): absence of refixation
    Herbert Silverstein
    Ear Research Foundation, Sarasota, Florida, USA
    Otol Neurotol 23:152-7. 2002
    ..To determine what percentage of patients with otosclerosis could successfully undergo a laser stapedotomy minus prosthesis over a 5-year period, and to determine the percentage of patients in whom refixation develops during follow-up...
  46. ncbi Mass loading on the ossicles and middle ear function
    R Z Gan
    Hough Ear Institute, Oklahoma City, OK 73112, USA
    Ann Otol Rhinol Laryngol 110:478-85. 2001
    ..We conclude that there is a quantitative limit to increased mass on the ossicular chain above which the mass will remarkably impair hearing thresholds...
  47. pmc Diagnostic utility of laser-Doppler vibrometry in conductive hearing loss with normal tympanic membrane
    John J Rosowski
    Department of Otology and Laryngology, Harvard Medical School, Boston, MA, USA
    Otol Neurotol 24:165-75. 2003
    ..More generally, we hypothesize that laser-Doppler vibrometry measurements of umbo velocity can give information about how differences in the impedance that the ossicles work against affect middle-ear function...
  48. ncbi Posterior and attic wall osteoplasty: hearing results and recurrence rates in cholesteatoma
    Gregorio Babighian
    Department of Otosurgery and Otoneurosurgery, Az Ospedaliera Università, Padua, Italy
    Otol Neurotol 23:14-7. 2002
    ..To assess the efficacy of a surgical technique, the temporary attic and posterior canal wall osteoplasty, in preventing cholesteatoma recurrence...
  49. ncbi [Revision tympanoplasty]
    G Geyer
    Klinik für Hals Nasen Ohren Heilkunde, Kopf und Halschirurgie, Städtisches Klinikum, Gotenstrasse 1, 42653 Solingen
    HNO 50:76-89; quiz 90-1. 2002
  50. ncbi Surgical repair of bone defects of the ear canal wall with flexible hydroxylapatite sheets: a pilot study
    D Zanetti
    Otolaryngology Department, University of Brescia, Piazzale Spedali Civili 1, 25100 Brescia, Italy
    Otol Neurotol 22:745-53. 2001
    ..Complete protection with a connective tissue graft is essential to avoid extrusion of the implant. The failure rate is significantly higher if otorrhea is present at the time of the operation...
  51. ncbi Mastoid obliteration: autogenous cranial bone pAte reconstruction
    Joseph B Roberson
    Otology, Neurotology, Skull Base Surgery, California Ear Institute at Stanford, Palo Alto, California 94304, USA
    Otol Neurotol 24:132-40. 2003
    ..To review the outcome in consecutive patients who have undergone complete epitympanic and mastoid obliteration and concurrent tympanic membrane reconstruction over a 53-month period...
  52. ncbi Hearing results of ossiculoplasty in Austin-Kartush group A patients
    S Iurato
    Department of Ophthalmology and Otolaryngology, University of Bari, Italy
    Otol Neurotol 22:140-4. 2001
    ..With alloplastic total prostheses, 36% of patients have a postoperative air-bone gap of 0 to 10 dB, and 74% have a postoperative air-bone gap of 0 to 20 dB...
  53. ncbi Bapx1 regulates patterning in the middle ear: altered regulatory role in the transition from the proximal jaw during vertebrate evolution
    Abigail S Tucker
    Department of Craniofacial Development and Orthodontics, Kings College London, Floor 28, Guy s Tower, Guy s Hospital, London SE1 9RT, UK
    Development 131:1235-45. 2004
    ..In non-mammalian jawed vertebrates, the bones homologous to the mammalian middle ear ossicles compose the proximal jaw bones that form the jaw articulation (primary jaw joint)...
  54. ncbi Lateralization during the Weber test: animal experiments
    Jean Yves Sichel
    Department of Otolaryngology Head and Neck Surgery, Hadassah University Hospital, Jerusalem, Israel
    Laryngoscope 112:542-6. 2002
    ..Thus, the out-of-phase signal arriving through the bony pathways will be decreased, hence increasing the resultant sound intensity stimulating the cochlea...
  55. pmc Fully implantable Otologics MET Carina device for the treatment of sensorineural hearing loss. Preliminary surgical and clinical results
    L Bruschini
    Otology and Cochlear Implants Division, University of Pisa, Italy
    Acta Otorhinolaryngol Ital 29:79-85. 2009
    ..severe sensorineural hearing loss and normal middle ears, providing a mechanical direct stimulation of middle ear ossicles. Recently, it has been successfully used also in patients with conductive hearing loss...
  56. ncbi Assembling a functional tympanic membrane: signals from the external acoustic meatus coordinate development of the malleal manubrium
    M Mallo
    Department of Developmental Biology, Max Planck Institute of Immunobiology, Stubeweg 51, D 79108 Freiburg, Germany
    Development 127:4127-36. 2000
    ..In addition, when the middle ear ossicles are allowed to develop in vitro under conditions that do not support further EAM development, the manubrium ..
  57. ncbi Otosclerosis of the incus
    Pedro Alberto Escada
    Departments of Otolaryngology, Egas Moniz Universitary Hospital, Lisbon, Portugal
    Otol Neurotol 28:301-3. 2007
    ..To report a case of a patient with otosclerosis of the incus...
  58. pmc Soft tissue morphometry of the malleus-incus complex from micro-CT imaging
    Jae Hoon Sim
    Department of Mechanical Engineering, Stanford University, Stanford, CA 94305, USA
    J Assoc Res Otolaryngol 9:5-21. 2008
    ..micro-CT) imaging, which is known to be a suitable method for imaging high-density tissue such as middle-ear ossicles and surrounding bones, is used in this study to determine the three-dimensional (3-D) morphometry of the soft ..
  59. ncbi How reproducibly can human ear ossicles be measured? A study of inter-observer error
    Stefan Flohr
    Department of Biology, University of Hildesheim, Hildesheim, Germany
    Anat Rec (Hoboken) 293:2094-106. 2010
    b>Ear ossicles have thus far received little attention in biological anthropology. For the use of these bones as a source of biological information, it is important to know how reproducibly they can be measured...
  60. ncbi Sound transmission in archaic and modern whales: anatomical adaptations for underwater hearing
    Sirpa Nummela
    Department of Anatomy, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio, USA
    Anat Rec (Hoboken) 290:716-33. 2007
    ..Measurements were made on 60 fossils of whole or partial skulls, isolated tympanics, middle ear ossicles, and mandibles from all six archaeocete families...
  61. ncbi Development of the dynamic structure (force lines) of the middle ear ossicles in human foetuses
    J Whyte
    Department of Human Anatomy and Histology, School of Medicine, University of Zaragoza, Spain
    Histol Histopathol 23:1049-60. 2008
    To study the ontogenic development of the organisation of the human middle ear ossicles structure.
  62. ncbi Eya1 expression in the developing ear and kidney: towards the understanding of the pathogenesis of Branchio-Oto-Renal (BOR) syndrome
    V Kalatzis
    Unité de Génétique des Déficits Sensoriels, URA CNRS 1968, Institut Pasteur Paris, France
    Dev Dyn 213:486-99. 1998
    ..canal and the surrounding mesenchyme to the auricular hillocks) and surrounding the primordia of the middle ear ossicles, and in the epithelium of the tubotympanic recess (the future tympanic cavity)...
  63. ncbi Development of tissue-engineered substitutes of the ear ossicles: PORP-shaped poly(propylene fumarate)-based scaffolds cultured with human mesenchymal stromal cells
    Serena Danti
    Center for Clinical Use of Stem Cells CUCCS RRMR, University of Pisa, Italy
    J Biomed Mater Res A 92:1343-56. 2010
    ..These preliminarily obtained outcomes may launch a new trend in otology dedicated to TE ossicle development to improve on the performance of current prosthetic replacements...
  64. ncbi Age-dependent effects of the onset of a conductive hearing loss on the volume of the cochlear nucleus subdivisions and the expression of c-fos in the mongolian gerbil (Meriones unguiculatus)
    O Gleich
    ENT Department, University of Regensburg, Germany
    Audiol Neurootol 2:113-27. 1997
    A monaural conductive hearing loss was induced by interrupting the chain of the middle ear ossicles on the right side in gerbils of four different age groups (P12-14, P20-21, P42 and P84)...
  65. ncbi Remarks on the inner ear of elasmobranchs and its interpretation from skeletal labyrinth morphology
    J G Maisey
    Division of Paleontology, American Museum of Natural History, Central Park West and 79th Street, New York, NY 10024 5192, USA
    J Morphol 250:236-64. 2001
    ..semi-directional phonoreception, even in the absence of any pressure-to-displacement transducer such as ear ossicles. The endolymphatic (parietal) fossa, semicircular canals, and crista (macula) neglecta are all adapted toward ..
  66. ncbi Prenatal diagnosis by isoenzymic differentiation of Treacher Collins' syndrome induced by retinoids in rats
    G Granstrom
    Department of Oto Rhino Laryngology, University of Gothenburg, Sweden
    Scand J Plast Reconstr Surg Hand Surg 24:177-83. 1990
    ..developed several malformations, including microtia, low set and dorsally placed outer ears, defective middle ear ossicles, short cochleas, defectively differentiated Meckel's cartilages, micrognathia, rudimentary malar bones, lateral ..
  67. ncbi Glass-ionomers: bioactive implant materials
    I M Brook
    Biomaterials Research Group, School of Clinical Dentistry, University of Sheffield, UK
    Biomaterials 19:565-71. 1998
    ..otologic surgery (Cochlear implant fixation, repair of the tympanic chain, eustation tube obliteration and as ear ossicles), and oral and reconstructive surgery...
  68. ncbi Elasticity modulus of rabbit middle ear ossicles determined by a novel micro-indentation technique
    Joris A M Soons
    Laboratory of Biomedical Physics, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Hear Res 263:33-7. 2010
    ..No significant differences between measurement locations were found, and we found an average Young's modulus of 16+/-3 GPa...
  69. ncbi High-frequency hearing in phocid and otariid pinnipeds: an interpretation based on inertial and cochlear constraints (L)
    Simo Hemilä
    Department of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland
    J Acoust Soc Am 120:3463-6. 2006
    ..Phocids, however, have massive middle ear ossicles, and underwater hearing has radically shifted towards higher frequencies...
  70. ncbi Evolution of sound localisation in land vertebrates
    Christine Köppl
    Sydney Medical School Physiology and Bosch Institute, University of Sydney, NSW 2006, Australia
    Curr Biol 19:R635-9. 2009
    ..the mammalian medial superior olive and the avian nucleus laminaris, need to be questioned and that important insights may arise from unexpected directions, such as the paleontology of middle-ear ossicles. There is still much to discover.
  71. ncbi Parental origin-specific developmental defects in mice with uniparental disomy for chromosome 12
    P Georgiades
    Department of Anatomy, University of Cambridge, Downing St, Cambridge CB2 3DY, UK
    Development 127:4719-28. 2000
    ..In embryos with mUPD12, the development of the neural crest-derived middle ear ossicles is defective...
  72. ncbi Middle ear defects associated with the double knock out mutation of murine goosecoid and Msx1 genes
    S Kuratani
    Dept of Biology, Fac of Sciences, Okayama University, Japan
    Cell Mol Biol (Noisy-le-grand) 45:589-99. 1999
    ..development and each mutant mouse displays intriguing facial abnormalities including those of middle ear ossicles, suggesting that both genes play roles in spatial programming of craniofacial regions...
  73. ncbi Three-dimensional finite element modeling of human ear for sound transmission
    Rong Z Gan
    School of Aerospace and Mechanical Engineering, University of Oklahoma, Norman, OK 73019, USA
    Ann Biomed Eng 32:847-59. 2004
    ..The acoustic-structural coupled FE analysis between the ear canal air column and middle ear ossicles was also conducted and the results revealed that the peak responses of both tympanic membrane and stapes ..
  74. ncbi Recombinant human bone morphogenetic protein-2/atelocollagen composite as a new material for ossicular reconstruction
    Ayako Takeuchi
    Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
    J Biomed Mater Res A 89:36-45. 2009
    ..There are many different prosthesis and techniques used to reconstruct the middle ear ossicles. However, precision in the surgical procedures and prostheses used for ossiculoplasty are still imperfect...
  75. ncbi Shrapnell's membrane in a mammal exposed to extreme pressure variations: morphological and radiological observations in the hooded seal
    Lars Eric Stenfors
    Department of Otolaryngology, Institute of Clinical Medicine, University of Tromsø, Tromsø, Norway
    J Laryngol Otol 117:756-62. 2003
    ..The main function of the lateral wall of the attic, including the minimal PF, appears to be to protect the middle-ear ossicles and allow movement of the malleus.
  76. ncbi Refining the locus of branchio-otic syndrome 2 (BOS2) to a 5.25 Mb locus on chromosome 1q31.3q32.1
    Bernard Thienpont
    Center for Human Genetics, University of Leuven, Leuven, Belgium
    Eur J Med Genet 52:393-7. 2009
    ..the other patient manifests mild conductive hearing loss resulting from bilaterally malformed middle ear ossicles, as well as a preauricular pit...
  77. ncbi Formation of the middle ear: recent progress on the developmental and molecular mechanisms
    M Mallo
    Department of Developmental Biology, Max Planck Institute of Immunobiology, Stubeweg 51, Freiburg, D 79108, Germany
    Dev Biol 231:410-9. 2001
    ..Gsc and Prx1 are essential for tympanic ring development. While invaginating, the EAM controls skeletogenesis in the underlying mesenchyme to form the manubrium of the malleus, the link between the membrane and the middle ear ossicles.
  78. ncbi Effect of bisphosphonate treatment in patients with Paget's disease of the skull
    J Donath
    National Institute of Rheumatology and Physiotherapy, Budapest, Hungary
    Rheumatology (Oxford) 43:89-94. 2004
    ..Hearing loss has long been known to be a complication of Paget's disease of bone. The aim of this study was to investigate Paget's disease of the temporal bone with special attention to hearing loss...
  79. ncbi Shape and derived geometrical parameters of the adult, human tympanic membrane measured with a phase-shift moiré interferometer
    W F Decraemer
    Laboratory of Biomedical Physics, University of Antwerp, Belgium
    Hear Res 51:107-21. 1991
    ..importance in the coupling of the acoustic sound pressure in the external ear canal to the motion of the middle ear ossicles. A moiré shift interferometer was used to measure with great precision the shape of the external surface of ..
  80. ncbi Comprehensive and interpretative radiology of middle ear malformations
    S M Louryan
    Laboratoire d'Anatomie et Embryologie Humaines, , Belgium
    Acta Otorhinolaryngol Belg 43:569-77. 1989
    ..and study of radioactive sulphur uptake in the mouse embryo permit to characterize some factors of middle ear ossicles formation...
  81. ncbi Ultraminiature encapsulated accelerometers as a fully implantable sensor for implantable hearing aids
    Woo Tae Park
    Department of Mechanical Engineering, Stanford University, Stanford, CA 94305, USA
    Biomed Microdevices 9:939-49. 2007
    ..The sensor is attached on the middle ear ossicles and measures the vibration transmitted from the tympanic membrane due to the sound in the ear canal...
  82. ncbi An ossified Meckel's cartilage in two Cretaceous mammals and origin of the mammalian middle ear
    Y Wang
    Institute of Vertebrate Paleontology and Paleoanthropology IVPP, Chinese Academy of Sciences, Post Office Box 643, Beijing, 100044, China
    Science 294:357-61. 2001
    ..may not be the initial factor that caused the separation of postdentary bones from the dentary as middle ear ossicles during mammalian evolution...
  83. ncbi Volumetric sub-surface imaging using spectrally encoded endoscopy
    D Yelin
    Department of Biomedical Engineering, Technion Israel Institute of Technology, Haifa 32000, Israel
    Opt Express 16:1748-57. 2008
    ..target through intralipid solution, and conduct volumetric imaging of a mouse embryo and excised human middle-ear ossicles. Our results demonstrate that real-time subsurface imaging is possible with this miniature endoscopy technique.
  84. ncbi [The deaf child: anatomy, etiologies and management]
    M Elmaleh-Berges
    Service d imagerie pédiatrique, Hopital Robert Debre, 48, boulevard Serurier, 75019 Paris, France
    J Radiol 87:1795-812. 2006
    ..Sensorineural hearing loss, even when unilateral, is predominantly due to malformation or infection and in rare cases to posterior fossa tumor...
  85. ncbi Is it the middle ear disease or the reconstruction material that determines the functional outcome in ossicular chain reconstruction?
    Uygar Levent Demir
    Department of Otolaryngology, Uludag University Medical School, Bursa, Turkey
    Otol Neurotol 33:580-5. 2012
    ..To evaluate the effects and the predictive value of environmental risk factors on the success of different reconstruction materials used in ossiculoplasty...
  86. ncbi Influence of the middle ear anatomy on the performance of a membrane sensor in the incudostapedial joint gap
    Martin Koch
    Clinic of Otorhinolaryngology, Department of Medicine, Technische Universitaet Dresden, Universitatsklinik Carl Gustav Carus, Fetscherstraße 74, 01307 Dresden, Haus 5, Germany
    Hear Res 301:35-43. 2013
    ..Measurements of the implanted sensor in temporal bone specimens showed a microphone sensitivity in the order of 1 mV/Pa. This article is part of a special issue entitled "MEMRO 2012"...
  87. ncbi [Implantable hearing aids]
    J C Luers
    HNO Klinik, Universitätsklinik Köln, 50924, Koln, Deutschland
    HNO 59:980-7. 2011
    ..Because the performance of the different implantable and nonimplantable hearing systems together with various surgical procedures are currently undergoing major changes, audiological indications may also develop in the future...
  88. ncbi [The avian middle ear (Struthio camelus). Data for the physiology of sound transmission in systems with a single ossicle in the chain]
    Luis Angel Vallejo Valdezate
    Universidad de Valladolid, Valladolid, Espana
    Acta Otorrinolaringol Esp 58:246-51. 2007
    ..The columella of birds, often cited in the literature, has yet to be adequately described. We aim to give an account of this transmission element, describing its anchoring systems and detailing the muscle associated to it...
  89. ncbi The effect of static force on round window stimulation with the direct acoustic cochlea stimulator
    Hannes Maier
    Institute of Audioneurotechnology VIANNA, Department of Experimental Otology, ENT Clinics, Medical University Hannover, Hannover, Germany
    Hear Res 301:115-24. 2013
    ..This article is part of a Special Issue entitled "MEMRO 2012"...
  90. ncbi [On the clinical application of spiral CT three-dimensional reconstruction of middle ear ossicles]
    Jie Sun
    Department of Otorhinolaryngology, First Affiliated Hospital, Xinjiang Medical University, Urumqi, 830054, China
    Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 26:865-7. 2012
    ....
  91. ncbi Congenital cholesteatoma clinical features and surgical results
    Hiromi Kojima
    Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan
    Am J Otolaryngol 27:299-305. 2006
    ..5% of the patients, so the columella on the foot plate method was most frequently used for ossiculoplasty, followed by the columella on the stapes method and the Wullstein type I method...
  92. ncbi A study on reconstruction of ossicular chain by an in situ bone tissue engineering technique
    Jian Jun Sun
    Center of Otorhinolaryngology of PLA, Naval General Hospital, Beijing, China
    Acta Otolaryngol 129:507-11. 2009
    ..The acellular cancellous bone with recombinant bone morphogenetic proteins 2 (rhBMP-2) could induce osteogenesis in the acoustic vesicle; this material might be used to reconstruct defects of the ossicular chain...
  93. ncbi [Advance or stabilization in the middle ear surgery]
    Tomasz Durko
    Klinika Otiatrii Katedry Otolaryngologii UM w Lodzi
    Otolaryngol Pol 60:501-6. 2006
  94. ncbi The relationship between individual ossicular status and conductive hearing loss in cholesteatoma
    Olga Martins
    Department of Neurology and Neuroscience, Weill Cornell Medical College, New York, New York 10065, USA
    Otol Neurotol 33:387-92. 2012
    ..To investigate and analyze the relationship between individual ossicular erosion and air-bone gap (ABG) among patients with cholesteatoma...
  95. ncbi High-frequency ex vivo ultrasound imaging of the auditory system
    Jeremy A Brown
    Dalhousie University, Halifax Nova Scotia, Canada B3H 1V7
    Ultrasound Med Biol 35:1899-907. 2009
    ..These images demonstrate that high-frequency ultrasound imaging of the middle and inner ear can provide valuable diagnostic information using minimally invasive techniques that could potentially be implemented in vivo...
  96. ncbi Quality-of-life assessment after primary and revision ear surgery using the chronic ear survey
    Kyu Hwan Jung
    Department of Otorhinolaryngology Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Arch Otolaryngol Head Neck Surg 136:358-65. 2010
    ..To measure subjective outcomes after primary and revision surgery for chronic ear disease...
  97. ncbi [Virtual endoscopy view of ossicular chain in the congenital aural atresia]
    Lixin Jiang
    Department of Otorhinolaryngology, The First Affiliated Hospital, Jinan University, Guangzhou, 510630, China
    Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 21:301-3. 2007
    ..To investigate the function of virtual endoscopy in assessing ossicular chain deformity in the congenital ear malformation...
  98. ncbi The impact of fixated glass ionomer cement and springy cortical bone incudostapedial joint reconstruction on hearing results
    Hatice Celik
    Department of Otorhinolaryngology and Head and Neck Surgery, Ministry of Health Ankara Training and Research Hospital, Ankara University School of Medicine, Ankara, Turkey
    Acta Otolaryngol 129:1368-73. 2009
    ..Although it abolishes the incudostapedial joint, use of glass ionomer cement to repair the defect between the stapes head and the long process of the incus is a successful procedure when the hearing results are considered...
  99. ncbi Time trend analysis of otological procedures performed in England, 1989 to 2005
    C K Hari
    Department of Otolaryngology Head and Neck Surgery, Royal Devon and Exeter Hospital, Exeter, UK
    J Laryngol Otol 121:1135-9. 2007
    ..To observe trends in the number of major otological procedures performed in England, in the context of advances in the understanding of disease...
  100. ncbi A self-adjusting ossicular prosthesis containing polyurethane sponge
    Hiroyuki Yamada
    Stanford University Medical Center, Department of Otolaryngology Head and Neck Surgery, Stanford, CA 94305 5328, USA
    Otol Neurotol 31:1404-8. 2010
    ..Middle ear ossicular replacement prostheses whose length can adjust in vivo to changes in middle ear dimensions following insertion may have acoustic advantages...
  101. ncbi Ossicular chain reconstruction using titanium versus hydroxyapatite implants
    Yuri M Gelfand
    Department of Otorhinolaryngology, University of Texas at Houston Medical School, Houston, Texas 77030, USA
    Otolaryngol Head Neck Surg 144:954-8. 2011
    ..Compare the efficacy of total and partial ossicular chain reconstruction using hydroxyapatite (HA) implants versus titanium (Ti) implants...

Research Grants12

  1. CLONING OF THE Hol MUTATION
    Licia Selleri; Fiscal Year: 2009
    ..Additionally, 04/014 mutants exhibit low-set and hypoplastic ear pinnae and their middle ear ossicles are severely affected...
  2. From infra- to ultrasound: Diversity in acoustic processing by the vertebrate ear
    Peter M Narins; Fiscal Year: 2010
    ..of four detailed investigations will be performed in order to (a) directly measure the motion of the middle ear ossicles in a "low-frequency" animal, the golden mole, in order to characterize the directional responses of the middle ..
  3. Genetic regulation of Inner and Middle Ear Development
    Andrew K Groves; Fiscal Year: 2013
    ..Moreover, the mesenchyme of the first and second branchial arches that generate the middle ear ossicles and the pinna begins to form in Foxi3 mutants, but rapidly succumbs to massive cell death...
  4. Magnetic Nanoparticles for Advanced Hearing Devices
    Charles Seeney; Fiscal Year: 2002
    ..1 will demonstrate feasibility of preparing hermetic ferromagnetic nanoparticles and attaching them to middle ear ossicles. Two different encapsulation technologies will be evaluated: 1) Thermal Plasma Deposition (TPD): rf-Inductive ..
  5. Exploring otoacoustic emissions with intracochlear pressure measurements
    Wei Dong; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  6. Ear Biomechanics for Restoration of Hearing
    RONG GAN; Fiscal Year: 2009
    ..Thus, the results will be essential for improving the diagnosis of OME, assessing surgical treatment for conductive hearing loss, and potentially improve the quality of life for millions of people. ..
  7. Sound Source Segregation and Determination
    Richard Fay; Fiscal Year: 2007
    ..We will focus on understanding the dimensions of neural activity that the brain could use in segregating and integrating simultaneous acoustic components from one or more sources. [unreadable] [unreadable]..
  8. Origins of Binaural Processing in Vertebrates
    Richard Fay; Fiscal Year: 2008
    ..abstract_text> ..
  9. Middle-ear assessment via reflectance measurements
    Susan Voss; Fiscal Year: 2005
    ..This work will both strengthen the research environment at Smith College and provide substantial research experiences for undergraduate students. ..
  10. Aged Middle Ear
    MICHAELANNE GRATTON; Fiscal Year: 2002
    ..These experiments may reveal a heretofore unrecognized component of the hearing loss seen in the elderly population. ..
  11. Development of a laser holography otoscope for diagnosis in the clinic
    John J Rosowski; Fiscal Year: 2010
    ..abstract_text> ..
  12. NEURAL MECHANISMS OF SOUND SOURCE IN VERTEBRATES
    Richard Fay; Fiscal Year: 2002
    ..These results will help in the development and evaluation of animal models for human hearing and help establish the comparative and evolutionary contexts within which the human sense of hearing can be better understood. ..