pressoreceptors

Summary

Summary: Receptors in the vascular system, particularly the aorta and carotid sinus, which are sensitive to stretch of the vessel walls.

Top Publications

  1. ncbi A "love triangle" elicited by electrochemistry: complex interactions among cardiac sympathetic afferent, chemo-, and baroreflexes
    Yan hua Du
    J Appl Physiol 102:9-10. 2007
  2. ncbi Differential distribution and function of hyperpolarization-activated channels in sensory neurons and mechanosensitive fibers
    Thanh N Doan
    Rammelkamp Center for Education and Research, MetroHealth Medical Center, and Department of Neurosciences, Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    J Neurosci 24:3335-43. 2004
  3. ncbi Medullary and supramedullary mechanisms regulating sympathetic vasomotor tone
    R A L Dampney
    Department of Physiology and Institute for Biomedical Research, University of Sydney, New South Wales, Australia
    Acta Physiol Scand 177:209-18. 2003
  4. ncbi Baroreceptor function during exercise: resetting the record
    Michael J Joyner
    Department of Anaesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Exp Physiol 91:27-36. 2006
  5. ncbi Baroreceptors and the long-term control of blood pressure
    Terry N Thrasher
    Department of Surgery, School of Medicine, University of Maryland, Baltimore, MD, USA
    Exp Physiol 89:331-5. 2004
  6. ncbi Inhibitory neurotransmission in the nucleus tractus solitarii: implications for baroreflex resetting during exercise
    Jeffrey T Potts
    Department of Biomedical Science, Dalton Cardiovascular Research Center, University of Missouri Columbia, Columbia, MO 65211, USA
    Exp Physiol 91:59-72. 2006
  7. ncbi Vanilloid receptors presynaptically modulate cranial visceral afferent synaptic transmission in nucleus tractus solitarius
    Mark W Doyle
    Department of Physiology and Pharmacology, Oregon Health and Science University, Portland, Oregon 97201 3098, USA
    J Neurosci 22:8222-9. 2002
  8. doi Rheos: an implantable carotid sinus stimulation device for the nonpharmacologic treatment of resistant hypertension
    Maria M Ng
    Department of Medicine, Ronald Reagan UCLA Medical Center, UCLA School of Medicine, Los Angeles, CA, USA
    Cardiol Rev 19:52-7. 2011
  9. doi Responses of neurons in paraventricular nucleus to activation of cardiac afferents and acute myocardial ischaemia in rats
    Bo Xu
    Department of Physiology, Nanjing Medical University, Nanjing 210029, China
    Exp Physiol 96:295-304. 2011
  10. ncbi The influence of low blood pressure and baroreceptor activity on pain responses
    A Angrilli
    Department of General Psychology, University of Padua, Padova, Italy
    Physiol Behav 62:391-7. 1997

Detail Information

Publications170 found, 100 shown here

  1. ncbi A "love triangle" elicited by electrochemistry: complex interactions among cardiac sympathetic afferent, chemo-, and baroreflexes
    Yan hua Du
    J Appl Physiol 102:9-10. 2007
  2. ncbi Differential distribution and function of hyperpolarization-activated channels in sensory neurons and mechanosensitive fibers
    Thanh N Doan
    Rammelkamp Center for Education and Research, MetroHealth Medical Center, and Department of Neurosciences, Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    J Neurosci 24:3335-43. 2004
    ..At the sensory receptor terminal, CsCl decreased the threshold pressure for initiation of mechanoreceptor discharge. Therefore, elimination of the I(H) increases excitability of both the soma and the peripheral sensory terminals...
  3. ncbi Medullary and supramedullary mechanisms regulating sympathetic vasomotor tone
    R A L Dampney
    Department of Physiology and Institute for Biomedical Research, University of Sydney, New South Wales, Australia
    Acta Physiol Scand 177:209-18. 2003
    ..This paper will briefly review some recent findings on the role of glutamate, GABA and angiotensin II (Ang II) receptors in maintaining the tonic activity of RVLM presympathetic neurons...
  4. ncbi Baroreceptor function during exercise: resetting the record
    Michael J Joyner
    Department of Anaesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Exp Physiol 91:27-36. 2006
    ..Additionally, the key contributions of John Shepherd and the late David Donald (along with their colleagues) on related issues are noted...
  5. ncbi Baroreceptors and the long-term control of blood pressure
    Terry N Thrasher
    Department of Surgery, School of Medicine, University of Maryland, Baltimore, MD, USA
    Exp Physiol 89:331-5. 2004
    ..These results strongly suggest that the role of baroreceptors in the long term control of MAP needs to be revisited...
  6. ncbi Inhibitory neurotransmission in the nucleus tractus solitarii: implications for baroreflex resetting during exercise
    Jeffrey T Potts
    Department of Biomedical Science, Dalton Cardiovascular Research Center, University of Missouri Columbia, Columbia, MO 65211, USA
    Exp Physiol 91:59-72. 2006
    ..An understanding of these mechanisms may prove to be essential for future detailed analysis of the cellular and molecular mechanisms underlying sensory integration in the NTS...
  7. ncbi Vanilloid receptors presynaptically modulate cranial visceral afferent synaptic transmission in nucleus tractus solitarius
    Mark W Doyle
    Department of Physiology and Pharmacology, Oregon Health and Science University, Portland, Oregon 97201 3098, USA
    J Neurosci 22:8222-9. 2002
    ..Because the CAP sensitivity of cranial afferents is exclusively associated with unmyelinated axons, VR1 identifies C-fiber afferent pathways within the brainstem...
  8. doi Rheos: an implantable carotid sinus stimulation device for the nonpharmacologic treatment of resistant hypertension
    Maria M Ng
    Department of Medicine, Ronald Reagan UCLA Medical Center, UCLA School of Medicine, Los Angeles, CA, USA
    Cardiol Rev 19:52-7. 2011
    ..Clinical trials designed to evaluate the efficacy and safety of this therapy in patients with treatment resistant hypertension, are now ongoing in both Europe and the United States...
  9. doi Responses of neurons in paraventricular nucleus to activation of cardiac afferents and acute myocardial ischaemia in rats
    Bo Xu
    Department of Physiology, Nanjing Medical University, Nanjing 210029, China
    Exp Physiol 96:295-304. 2011
    ..Acute myocardial ischaemia activates capsaicin-sensitive neurons in PVN and enhances sympathetic outflow...
  10. ncbi The influence of low blood pressure and baroreceptor activity on pain responses
    A Angrilli
    Department of General Psychology, University of Padua, Padova, Italy
    Physiol Behav 62:391-7. 1997
    ..Contrary to expectations, the rate of choice of baroreceptor conditions during painful stimulation did not show, in either group, any preference for baroreceptor activation...
  11. pmc The polyvagal perspective
    Stephen W Porges
    University of Illinois at Chicago, Brain Body Center, Department of Psychiatry, Chicago, IL 60612, USA
    Biol Psychol 74:116-43. 2007
    ....
  12. pmc Effects of baroreceptor activation on respiratory variability in rat
    Simon McMullan
    Australian School of Advanced Medicine, Macquarie University, 3 Innovation Road, Sydney, NSW 2109, Australia
    Respir Physiol Neurobiol 166:80-6. 2009
    ..In contrast to the effects of baroreceptor stimulation on sympathetic nerve activity, the baro-respiratory response is subtle and highly dependent on respiratory drive...
  13. ncbi Modulation of the human nociceptive flexion reflex across the cardiac cycle
    L Edwards
    School of Sport and Exercise Sciences, University of Birmingham, United Kingdom
    Psychophysiology 38:712-8. 2001
    ..Stimulation of baroreceptors by natural changes in blood pressure during the cardiac cycle dampened nociception, and accordingly, the data support the arterial baroreflex mechanism of hypertensive hypoalgesia...
  14. ncbi Sensory detection thresholds are modulated across the cardiac cycle: evidence that cutaneous sensibility is greatest for systolic stimulation
    L Edwards
    Department of Human Sciences, Loughborough University, Leicestershire, UK
    Psychophysiology 46:252-6. 2009
    ..The finding that cutaneous sensibility was greater when stimulated during systole than diastole may be accounted for by a modified afferent feedback hypothesis...
  15. ncbi Acute device-based blood pressure reduction: electrical activation of the carotid baroreflex in patients undergoing elective carotid surgery
    Jurg Schmidli
    Department of Cardiovascular Surgery, University Hospital, Berne, Switzerland
    Vascular 15:63-9. 2007
    ....
  16. ncbi Increased baroreceptor response in mice deficient in monoamine oxidase A and B
    D P Holschneider
    Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, LAC USC Hosp, University of Southern California Los Angeles 90024, USA
    Am J Physiol Heart Circ Physiol 282:H964-72. 2002
    ..These data suggest that prevention of hypertension may occur in chronic states of catecholaminergic/indoleaminergic excess by increased gain of the baroreflex...
  17. ncbi Arterial baroreflex resetting during exercise: a current perspective
    Peter B Raven
    The Department of Integrative Physiology, University of North Texas, Health Science Center, TX 76107, USA
    Exp Physiol 91:37-49. 2006
    ....
  18. ncbi Nitric oxide modulation of glutamatergic, baroreflex, and cardiopulmonary transmission in the nucleus of the solitary tract
    Ana Carolina Rodrigues Dias
    Department of Physiology, Universidade Federal de Sao Paulo Escola Paulista de Medicina, Brazil
    Am J Physiol Heart Circ Physiol 288:H256-62. 2005
    ..Our results indicate that inhibition of NOS within the NTS attenuates baro- and cardiopulmonary reflexes, suggesting that NO plays a physiologically significant neuromodulatory role in cardiovascular regulation...
  19. ncbi The hypo-osmolality of pregnancy does not alter baroreceptor responses to acute changes in osmolality
    Tina Hines
    University of Missouri, Kansas City School of Nursing, Kansas City, MO 64108, USA
    Biol Res Nurs 7:214-21. 2006
    ..Their findings suggest that in vitro data from male rats indicating a correlation between pOsm and baroreceptor discharge are not applicable in anesthetized intact female animals...
  20. ncbi Protamine after heparin produces hypotension resulting from decreased sympathetic outflow secondary to increased nitric oxide in the central nervous system
    Yoshikazu Hamada
    Department of Anesthesiology, Tokyo Medical University, 6 7 1 Nishi shinjuku, Shinjuku, Tokyo, 160 0023 Japan
    Anesth Analg 100:33-7. 2005
    ....
  21. ncbi Impairment of parasympathetic baroreflex responses in migraine patients
    E O Sanya
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Germany
    Acta Neurol Scand 111:102-7. 2005
    ..The aim of this study was to assess baroreflex regulation of the heart rate and blood vessels in migraine patients in comparison with healthy controls...
  22. ncbi Sympathetic nerve activity in response to hypotensive stress in the postural tachycardia syndrome
    Istvan Bonyhay
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass 02215, USA
    Circulation 110:3193-8. 2004
    ..Little is known about sympathetic nerve outflow and its role in hemodynamic control in this disorder...
  23. ncbi Vestibulosympathetic reflex mediates the pressor response to hypergravity in conscious rats: contribution of the diencephalon
    Tomoko Matsuda
    Department of Physiology, Gifu University School of Medicine, 1 1 Yanagido, Gifu 501 1194, Japan
    Brain Res 1028:140-7. 2004
    ..These results indicate that output from the vestibular system project to the diencephalon, and activation of diencephalic nuclei is indispensable to the pressor response via the sympathetic nerve system...
  24. ncbi Direct injection of substance P-antisense oligonucleotide into the feline NTS modifies the cardiovascular responses to ergoreceptor but not baroreceptor afferent input
    Carole A Williams
    Department of Physiology, College of Medicine, East Tennessee State University, P O Box 70576, Johnson City, TN 37614, USA
    Brain Res 963:26-42. 2003
    ..We suggest that the SP released during isometric contractions excites an inhibitory pathway modulating baroreceptor input, thus contributing to the increase in mean blood pressure...
  25. ncbi Dysfunctional baroreflex regulation of sympathetic nerve activity in patients with vasovagal syncope
    Markus Bechir
    Cardiovascular Center, Cardiology, University Hospital, Ramistrasse 100, 8091 Zurich, Switzerland
    Circulation 107:1620-5. 2003
    ..Hence, the aim of the present study was to investigate MSA, baroreceptor sensitivity, heart rate, and blood pressure under resting conditions and during orthostatic stress in patients with a history of vasovagal syncope...
  26. ncbi Dynamic interactions between arterial pressure and sympathetic nerve activity: role of arterial baroreceptors
    Claude Julien
    Départmwnt de Physiologie et Pharmacie Clinique, Faculte de Pharmacie, Université Claude Bernad Lyon, Lyon, France
    Am J Physiol Regul Integr Comp Physiol 285:R834-41. 2003
    ..The weak coupling between slow fluctuations of RSNA and MAP in sham-operated and SAD rats points to the interference of noise sources unrelated to RSNA affecting MAP and of noise sources unrelated to MAP affecting RSNA...
  27. ncbi Baroreflex control of muscle sympathetic nerve activity after carotid body tumor resection
    Henri J L M Timmers
    Department of General Internal Medicine, University Medical Center Nijmegen, Nijmegen, The Netherlands
    Hypertension 42:143-9. 2003
    ..During the Valsalva maneuver, loss of carotid baroreflex control of heart rate is less well compensated for by the extra carotid baroreceptors than the control of muscle sympathetic nerve activity...
  28. ncbi Cardiovascular regulation after destruction of the C1 cell group of the rostral ventrolateral medulla in rats
    Christopher J Madden
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Am J Physiol Heart Circ Physiol 285:H2734-48. 2003
    ..These data suggest that RVLM-C1 cells contribute to the maintenance of baseline arterial pressure and play an integral role in sympathoexcitatory responses...
  29. ncbi Effects of lower body negative pressure on cardiac and vascular responses to carotid baroreflex stimulation
    C M Brown
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Physiol Res 52:637-45. 2003
    ..Enhanced blood pressure responses to neck suction during higher levels of LBNP are not necessarily the result of a reflex interaction but may serve to protect the circulation from fluctuations in blood pressure while standing...
  30. ncbi Steady-state and dynamic responses of renal sympathetic nerve activity to air-jet stress in sinoaortic denervated rats
    Christian Barrès
    Faculte de Pharmacie, 8, avenue Rockefeller, 69373 Lyon Cedex 08, France
    Hypertension 43:629-35. 2004
    ....
  31. ncbi Alpha-2 adrenergic transmission and human baroreflex regulation
    Jens Tank
    Department of Nephrology and Hypertension, Franz Volhard Clinic, Medical Faculty of the Charité and HELIOS Klinikum, Berlin, Germany
    Hypertension 43:1035-41. 2004
    ..alpha-2 Adrenoceptor stimulation greatly augments baroreflex-mediated bradycardia, most likely by parasympathetic activation...
  32. ncbi Brain stem control of arterial pressure in chronic arterial baroreceptor-denervated rats
    Ann M Schreihofer
    Dept of Physiology, Medical College of Georgia, 1120 15th St, Augusta, GA 30912 3000, USA
    Am J Physiol Regul Integr Comp Physiol 289:R1746-55. 2005
    ..Baroreceptor-independent regulation of the ventrolateral medulla may underlie central mechanisms contributing to the long-term control of AP...
  33. ncbi Frequency-dependent baroreflex control of blood pressure and heart rate during physical exercise
    Giammario Spadacini
    Dipartimento di Medicina Interna IRCCS S Matteo and University of Pavia, Italy
    Int J Cardiol 107:171-9. 2006
    ..We hypothesised that this uncertainty arose from the differing responses of the vagus (fast) and sympathetic (slow) arms of the autonomic effectors, and to differing sympatho-vagal balance at different exercise intensities...
  34. ncbi Baroreflex mechanisms regulating mean level of SNA differ from those regulating the timing and entrainment of the sympathetic discharges in rabbits
    Simon C Malpas
    Circulatory Control Laboratory, Department of Physiology, University of Auckland Medical School, Private Bag 92019, Auckland, New Zealand
    Am J Physiol Regul Integr Comp Physiol 291:R400-9. 2006
    ..This observation has important implications for understanding the origin and regulation of SNA...
  35. doi Analysis of heart period and arterial pressure variability in childhood hypertension: key role of baroreflex impairment
    Simonetta Genovesi
    Clinica Nefrologica, S Gerardo Hospital, University of Milano Bicocca, Milan, Italy
    Hypertension 51:1289-94. 2008
    ..A similar baroreflex impairment is also observed in the prehypertensive state. Baroreflex assessment could furnish additional information in the clinical assessment of pediatric hypertension...
  36. ncbi Estimation of the total peripheral resistance baroreflex impulse response from spontaneous hemodynamic variability
    Xiaoxiao Chen
    Department of Electrical and Computer Engineering, Michigan State University, 2120 Engineering Bldg, East Lansing, MI 48824, USA
    Am J Physiol Heart Circ Physiol 294:H293-301. 2008
    ..7 +/- 0.44 to -1.8 +/- 0.2 (P < 0.05)] following the chronic intervention. Moreover, the technique yielded estimates whose values were consistent with those reported with more invasive and/or experimentally difficult methods...
  37. ncbi Quantification of cardiac baroreflex function at rest and during autonomic stimulation
    Stefan Duschek
    Department Psychologie, Ludwig Maximilians Universitat Munchen, Leopoldstr 13, 80802 Munich, Germany
    J Physiol Sci 57:259-68. 2007
    ..The sensitivity index must be considered the most relevant to quantify baroreflex function among the three parameters...
  38. pmc Circulating angiotensin II attenuates the sympathetic baroreflex by reducing the barosensitivity of medullary cardiovascular neurones in the rat
    Simon McMullan
    Hypertension and Stroke Research Laboratory, University of Sydney, NSW, Australia
    J Physiol 582:711-22. 2007
    ..We suggest that this results from activation by Ang II of a central pathway originating at the circumventricular organs...
  39. doi Reflex control of sympathetic outflow and depressed baroreflex sensitivity following myocardial infarction
    Christine M Jones
    Department of Internal Medicine Cardiology, Medical College of Virginia Campus of Virginia Commonwealth University, United States
    Auton Neurosci 141:46-53. 2008
    ..These results provide additional support for the hypothesis that depressed reflex control of heart rate following myocardial infarction is related to augmented afferent input from the left ventricle...
  40. pmc Intrathecal cGMP elicits pressor responses and maintains mean blood pressure during haemorrhage in anaesthetized rats
    V Malik
    Cardiology Research, Royal Perth Hospital Unit, School of Medicine and Pharmacology, The University of Western Australia, GPO Box X2213, Perth 6487 Australia
    J Physiol 581:543-52. 2007
    ..The results indicate that cGMP increases blood pressure, and thus suggest that cGMP increases SNA. This supports the hypothesis that the sympathoexcitatory effects of spinal delivery of NO are mediated by a cGMP-dependent mechanism...
  41. pmc Targeted deletion of neurokinin-1 receptor expressing nucleus tractus solitarii neurons precludes somatosensory depression of arterial baroreceptor-heart rate reflex
    J T Potts
    Department of Biomedical Science, College of Veterinary Medicine, Dalton Cardiovascular Research Center, University of Missouri, 134 Research Park Drive, Columbia, MO 65211, USA
    Neuroscience 145:1168-81. 2007
    ..These findings indicate that immunolesioning of NK1-R expressing NTS neurons selectively abolishes the depressive effect of somatosensory input on arterial baroreceptor-heart rate reflex function...
  42. pmc Differential effects of cardiac sympathetic afferent stimulation on neurons in the nucleus tractus solitarius
    Wei Zhong Wang
    Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE 68198 5850, USA
    Neurosci Lett 409:146-50. 2006
    ....
  43. ncbi Systemic cholecystokinin differentially affects baro-activated GABAergic neurons in rat caudal ventrolateral medulla
    Susan C Mobley
    Department of Physiology, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912 3000, USA
    J Neurophysiol 96:2760-8. 2006
    ..The differential responses of baro-activated GABAergic CVLM neurons to CCK may contribute to the diverse responses of presympathetic RVLM neurons and sympathetic outflows observed with systemic CCK...
  44. ncbi Effects of nine antihypertensive drugs on blood pressure variability in sinoaortic-denervated rats
    Jin Wang
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 27:1013-7. 2006
    ..The present work was designed to investigate the effects of nine commonly used antihypertensive drugs on blood pressure (BP) and blood pressure variability (BPV) in conscious sinoaortic-denervated (SAD) rats...
  45. ncbi Exercise training improves aortic depressor nerve sensitivity in rats with ischemia-induced heart failure
    Eduardo Rondon
    Heart Institute Instituto do Coração, University of Sao Paulo, Brazil
    Am J Physiol Heart Circ Physiol 291:H2801-6. 2006
    ..05). In conclusion, exercise training improves AODN sensitivity in HF rats...
  46. ncbi Baroreceptor reflex sensitivity estimated by the sequence technique is reliable in rats
    Harald M Stauss
    Am J Physiol Heart Circ Physiol 291:H482-3. 2006
  47. ncbi Evidence for cardiovascular autonomic dysfunction in neonates with coarctation of the aorta
    Jaimie W Polson
    Department of Clinical Sciences at South Bristol, School of Medical Sciences, Bristol Heart Institute, University of Bristol, Bristol, United Kingdom
    Circulation 113:2844-50. 2006
    ..We hypothesized that early pathological adjustment of autonomic cardiovascular function may already be established in the neonate with coarctation...
  48. ncbi Dissociation of blood pressure and sympathetic activation of renin release in sinoaortic-denervated rats
    Marta H Krieger
    Department of Physiology and Biophysics, Institute of Biology, State University of Campinas, Campinas, SP, Brazil
    Clin Exp Pharmacol Physiol 33:471-6. 2006
    ..86 +/- 0.77 ng AngI/mL per h; n = 5; P < 0.05). Renin mRNA levels in the kidneys were unchanged in all groups. 6. These results show that an elevation in BP appears to offset increased renal sympathetic discharge with no change in PRA...
  49. ncbi Differential baroreceptor modulation mediated by the ventrolateral medulla
    Cássia de Toledo Bergamaschi
    Departamento de Fisiologia, Universidade Federal de Sao Paulo Escola Paulista de Medicina, Rua Botucatu, 862, CEP 04023 060, Sao Paulo, SP, Brazil
    Auton Neurosci 126:156-62. 2006
    ..Glutamatergic activation of CPA neurons can cause large increases in the rSNA and BP with a weaker baroreceptor modulation when compared to responses mediated by the RVLM neurons...
  50. ncbi Effects of high NaCl diet on arterial pressure in Sprague-Dawley rats with hepatic and sinoaortic denervation
    Shuang Gao
    Department of Physiology, Gifu University School of Medicine, 1 1 Yanagido, Gifu 501 1194, Japan
    Jpn J Physiol 55:229-34. 2005
    ..e., in SAD+HD rats, mean arterial pressure increased by 13 +/- 1 mmHg. In conclusion, sinoaortic baroreceptor, but not hepatic Na(+) receptor, has a significant role in the long-term regulation of arterial pressure on a high NaCl diet...
  51. ncbi Muscle mechanoreflex augments arterial baroreflex-mediated dynamic sympathetic response to carotid sinus pressure
    Kenta Yamamoto
    Consolidated Research Institute for Advanced Science and Medical Care, Waseda University, 513 Wasedatsurumakicho, Tokyo 162 0041, Japan
    Am J Physiol Heart Circ Physiol 295:H1081-H1089. 2008
    ..3.1 +/- 1.5 au; P < 0.05, control vs. stretch) in the SNA step response. A simulation experiment using the results indicated that the muscle mechanoreflex would accelerate the closed-loop AP regulation via the arterial baroreflex...
  52. ncbi Verapamil protective effect on natural and artificial magnetic field cardiovascular impact
    Juraj Gmitrov
    Department of Physiological Hygiene, The National Institute of Public Health, Tokyo, Japan
    Bioelectromagnetics 23:531-41. 2002
    ..SMF and GMF probably affect baroreceptor sensory transduction, modulating baroreceptor membranes' Ca(2+) channel permeability...
  53. ncbi Artificial static and geomagnetic field interrelated impact on cardiovascular regulation
    Juraj Gmitrov
    Department of Physiological Hygiene, National Institute of Public Health, Tokyo, Japan
    Bioelectromagnetics 23:329-38. 2002
    ....
  54. ncbi Influence of vestibulo-sympathetic reflex on muscle sympathetic outflow during head-down tilt
    J Kawanokuchi
    Department of Neuroimmunology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan
    Environ Med 45:66-8. 2001
    ..1 G. It is estimated that the vestibulo-sympathetic reflex may suppress sympathetic outflow to muscles in humans...
  55. ncbi Both central command and exercise pressor reflex reset carotid sinus baroreflex
    S A McIlveen
    Division of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, California 95616, USA
    Am J Physiol Heart Circ Physiol 280:H1454-63. 2001
    ..Our findings show that central command arising from the MLR as well as the exercise pressor reflex are capable of resetting the carotid baroreflex...
  56. ncbi Baroreceptor reflex function
    Harald M Stauss
    Johannes Müller Institut für Physiologie, Humboldt Universität zu Berlin Charité, 10117 Berlin, Germany
    Am J Physiol Regul Integr Comp Physiol 283:R284-6. 2002
  57. ncbi Acute sympathoexcitatory action of angiotensin II in conscious baroreceptor-denervated rats
    Ling Xu
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Am J Physiol Regul Integr Comp Physiol 283:R451-9. 2002
    ..Furthermore, these studies highlight the importance of fully characterizing sinoaortic-denervated rats used in experiments examining the role of baroreceptor reflexes...
  58. ncbi Reflex control of arterial pressure and heart rate in short-term streptozotocin diabetic rats
    P Dall'Ago
    Departamento de Fisiologia, Instituto de Ciencias Basicas da Saude, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil
    Braz J Med Biol Res 35:843-9. 2002
    ....
  59. ncbi [Baroreflexes and congestive heart failure]
    M C Aumont
    Service de cardiologie A, , Paris
    Arch Mal Coeur Vaiss 88:555-8. 1995
    ..Aldosterone is one of the factors which could activate the Na-K ATPase, as this hormone directly increases pump activity and favorizes the synthesis of new pumps in the vascular smooth muscle cells.(ABSTRACT TRUNCATED AT 250 WORDS)..
  60. pmc Two sites for modulation of human sympathetic activity by arterial baroreceptors?
    P Kienbaum
    Institute of Clinical Neuroscience, Unit of Clinical Neurophysiology, Sahlgren Hospital, University of Goteborg, Sweden
    J Physiol 531:861-9. 2001
    ..We suggest that the modulation occurs at two sites, one which determines whether or not a burst will occur, and another at which the strength of the discharge is determined...
  61. ncbi Effects of head-up tilting on baroreceptor control in subjects with different tolerances to orthostatic stress
    V L Cooper
    Institute for Cardiovascular Research, University of Leeds, Leeds LS2 9JT, U K
    Clin Sci (Lond) 103:221-6. 2002
    ....
  62. ncbi Dynamic analysis of renal nerve activity responses to baroreceptor denervation in hypertensive rats
    G F DiBona
    Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    Hypertension 37:1153-63. 2001
    ....
  63. ncbi AT(1)-receptor blockade in the hypothalamic PVN reduces central hyperosmolality-induced renal sympathoexcitation
    Q H Chen
    Department of Physiology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA
    Am J Physiol Regul Integr Comp Physiol 281:R1844-53. 2001
    ..Results suggest that elevated RSNA after central sodium/osmotic activation is mediated, at least in part, by a synaptic mechanism involving AT(1)-receptor activation within the PVN...
  64. ncbi Reduced baroreceptor reflex sensitivity and increased blood pressure variability at 2400 m simulated cabin altitude
    Knut Sevre
    Department of Cardiology, Ulleval University Hospital, Oslo, Norway
    Aviat Space Environ Med 73:632-4. 2002
    ..5 +/- 3.1 vs. 13.2 +/- 2.0 ms x mm Hg(-1) and 5.4 +/- 1.3 vs. 8.2 +/- 1.1 mm Hg, respectively; p < 0.05). We conclude that autonomic cardiovascular control was disturbed during acute exposure to an air pressure corresponding to 2400 m...
  65. ncbi Haemorrhage-evoked compensation and decompensation are mediated by distinct caudal midline medullary regions in the urethane-anaesthetised rat
    D J Heslop
    Department of Anatomy and Histology, The University of Sydney, Sydney, NSW 2006, Australia
    Neuroscience 113:555-67. 2002
    ....
  66. ncbi Central hypercapnic chemoreflex modulation of renal sympathetic nerve activity in experimental heart failure
    A V Kristen
    Abteilung Innere Medizin III, Kardiologie, Angiologie, Pulmologie, Universitat Heidelberg, Germany
    Basic Res Cardiol 97:177-86. 2002
    ....
  67. ncbi Forebrain renin-angiotensin system has a tonic excitatory influence on renal sympathetic nerve activity
    Shun Guang Wei
    Research Service, Veterans Affairs Medical Center and Department of Internal Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Am J Physiol Heart Circ Physiol 282:H890-5. 2002
    ..g., heart failure) in which baroreflex mechanisms are impaired and RAS activity is augmented...
  68. ncbi [Representation of the pulse wave of blood pressure by the series of impulses of the pulse-rhythmic neurons in the nucleus tractus solitarii]
    Vytautas Miliukas
    Kauno medicinos universiteto Biomedicininiu tyrimu institutas, Kaunas
    Medicina (Kaunas) 38:553-8. 2002
    ..The similarity of the histograms to the pulse wave shows that the pulse-rhythmic neurons integrate mostly the afferent input received from the arterial baroreceptors...
  69. ncbi High-cut characteristics of the baroreflex neural arc preserve baroreflex gain against pulsatile pressure
    Toru Kawada
    Department of Cardiovascular Dynamics, National Cardiovascular Center Research Institute, Osaka 565 8565, Japan
    Am J Physiol Heart Circ Physiol 282:H1149-56. 2002
    ..8 Hz. A numerical simulation indicated that the high-cut characteristics above 0.8 Hz were effective to attenuate the pulsatile signal and preserve the open-loop gain when the baroreflex dynamic range was finite...
  70. ncbi Arterial baroreceptors mediate the inhibitory effect of acute increases in arterial blood pressure on thirst
    Sean D Stocker
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Am J Physiol Regul Integr Comp Physiol 282:R1718-29. 2002
    ..Thus it appears that arterial baroreceptor afferents mediate the inhibitory effect of an acute increase in AP on thirst stimulated by ANG II or hyperosmolality...
  71. pmc Characteristics of ongoing and reflex discharge of single splenic and renal sympathetic postganglionic fibres in cats
    R L Meckler
    Department of Physiology, Michigan State University, East Lansing 48824 1101
    J Physiol 396:139-53. 1988
    ..4. Firing of splenic fibres was less inhibited than that of renal fibres by stimulation of pressoreceptors with phenylephrine-induced increases in blood pressure...
  72. ncbi Modeling arterial hypotension during hemodialysis
    M Ursino
    Department of Electronics, Computer Science and Systems, University of Bologna, Italy
    Artif Organs 21:873-90. 1997
    ..The control mechanisms are triggered by information coming from both arterial and cardiopulmonary pressoreceptors, and they work on systemic arterial resistance, heart rate, and systemic venous unstressed volume...
  73. doi Elderly hypertensives: how are they different?
    Stanley S Franklin
    Heart Disease Prevention Program, University of California, Irvine, CA 92697, USA
    J Clin Hypertens (Greenwich) 14:779-86. 2012
    ..The emphasis will be on the multiple ways that increased artery stiffness affects the natural history and clinical manifestations of hypertension in the elderly...
  74. doi Experimental hyperleptinemia acutely increases vasoconstrictory sympathetic nerve activity in healthy humans
    Felix Machleidt
    Department of Internal Medicine I, University Hospital of Schleswig Holstein, Campus Lubeck, D 23538 Lubeck, Germany
    J Clin Endocrinol Metab 98:E491-6. 2013
    ..In the present study, we characterize the effects of acute hyperleptinemia on microneurographically recorded SNA in humans...
  75. pmc Spinal cord GABA receptors modulate the exercise pressor reflex in decerebrate rats
    Han Jun Wang
    Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE 68198 5850, USA
    Am J Physiol Regul Integr Comp Physiol 305:R42-9. 2013
    ....
  76. ncbi Effects of antihypertensive drugs on ultrasound production and cardiovascular responses in 15-day-old rats
    Mark S Blumberg
    Program in Behavioral and Cognitive Neuroscience, Department of Psychology, The University of Iowa, E11 Seashore Hall, Iowa City, IA 52242, USA
    Behav Brain Res 131:37-46. 2002
    ....
  77. ncbi Beat-to-beat blood pressure analysis after premature ventricular contraction indicates sensitive baroreceptor dysfunction in Parkinson's disease
    Carl Albrecht Haensch
    Autonomic Laboratory, Department of Neurology of the University of Witten Herdecke, HELIOS Klinikum Wuppertal, Germany
    Mov Disord 21:486-91. 2006
    ..The advantage of this method results from the independence of patients cooperation and the high sensitivity to prove a sympathetic neurocirculatory failure within 10 heart beats...
  78. ncbi Cardiovascular effects of beta-blockers with and without intrinsic sympathomimetic activity. A comparison between celiprolol and metoprolol
    K Heusser
    Human Cardiovascular Physiology Laboratory, Medical Clinic IV, Department of Internal Medicine, University of Erlangen Nuremberg, Erlangen, Germany
    Kidney Blood Press Res 25:34-41. 2002
    ..Celiprolol, a newer beta-blocking agent, has been reported to have vasodilatory capacity which may be due to partial beta-2-receptor agonistic activity or to alpha-receptor antagonistic or central sympathoinhibitory effects...
  79. ncbi Distribution and amino acid content of enkephalin-immunoreactive inputs onto juxtacellularly labelled bulbospinal barosensitive neurons in rat rostral ventrolateral medulla
    I J Llewellyn-Smith
    Department of Medicine, Flinders University, Bedford Park, SA, Australia
    Neuroscience 108:307-22. 2001
    ..The data suggest that endogenous enkephalin inhibits amino acid release from terminals that innervate bulbospinal barosensitive neurons of the rostral ventrolateral medulla...
  80. doi Episodic syncope in hypertrophic cardiomyopathy: evidence for inappropriate vasodilation
    K Prasad
    Department of Cardiovascular Medicine, University of Birmingham, Edgbaston, Birmingham, UK
    Heart 94:1312-7. 2008
    ..12 We hypothesised that abnormal vasodepressor-mediated hypotension may also occur during daily life in patients with HCM, and that this may be an important mechanism of syncope when conventional investigations fail to reveal a cause...
  81. ncbi Central cardiovascular actions of vasopressin in the rat
    C Lebrun
    German Institute for High Blood Pressure Research, University of Heidelberg, F R G
    Can J Physiol Pharmacol 65:1712-6. 1987
    ....
  82. ncbi Effects of smoking on cardiopulmonary baroreceptor activation and peripheral vascular resistance
    E Arosio
    Division of Cardiovascular Rehabilitation, University of Verona, Valeggio Hospital, Verona, Italy
    Eur J Clin Invest 36:320-5. 2006
    ..We calculated forearm resistance and carotid wall tension. We also studied R-R variability, calculating the ratio between low frequency (LF) and high frequency (HF) R-R interval variability...
  83. ncbi Persistence of baroreceptor control of cerebral blood flow velocity at a simulated altitude of 5000 m
    Claudio Passino
    Department of Internal Medicine, University of Pavia and IRCCS S Matteo, Pavia, and Department of Internal Medicine, Unita Ospedaliera S Maria Nuova, Firenze, Italy
    J Hypertens 25:1862-70. 2007
    ..To assess the effects of acute exposure to simulated high altitude on baroreflex control of mean cerebral blood flow velocity (MCFV)...
  84. ncbi Mechanism of the hypotensive action of anandamide in anesthetized rats
    K Varga
    Department of Pharmacology and Toxicology, Virginia, Commonwealth University, Medical College of Virginia, Richmond 23298, USA
    Hypertension 28:682-6. 1996
    ....
  85. ncbi Role of angiotensin II receptor subtypes in mediating the sympathoexcitatory effects of exogenous and endogenous angiotensin peptides in the rostral ventrolateral medulla of the rabbit
    Y Hirooka
    Department of Physiology and Institute for Biomedical Research, University of Sydney, N S W, Australia
    Brain Res 772:107-14. 1997
    ....
  86. ncbi Sympathetic influence on cardiovascular responses to sustained head-up tilt in humans
    M Pedersen
    Department of Anaesthesia, University of Copenhagen, Denmark
    Acta Physiol Scand 155:435-44. 1995
    ..In conclusion, sympathetic activation was crucial for the heart rate elevation during normotensive head-up tilt, but not for tilt tolerance or for the associated hypotension and bradycardia...
  87. ncbi The effects of patterned breathing and continuous positive airway pressure on cardiovascular regulation in healthy volunteers
    T Torok
    Medical Intensive Care Unit, Albert Szent Gyorgyi Medical University, Szeged, Hungary
    Acta Physiol Hung 85:1-10. 1997
    ..In contrast the active breathing with CPAP exerts mechanical effects which in turn present an augmented systemic baroreflex trigger, however, the baroreflex sensitivity remains unchanged...
  88. ncbi Responses of lumbar vasoconstrictor neurons supplying different vascular beds to graded baroreceptor stimuli in the cat
    M Michaelis
    Physiologisches Institut, , Kiel, FRG
    J Auton Nerv Syst 42:241-9. 1993
    ..In contrast, two-thirds of the postganglionic cutaneous vasoconstrictor (CVC2) neurons exhibited a significantly weaker barosensitivity. The functional implications are discussed...
  89. ncbi Seidel-Herzel model of human baroreflex in cardiorespiratory system with stochastic delays
    Aleksandra Dudkowska
    Institute of Theoretical Physics and Astrophysics, University of Gdańsk ul, Wita Stwosza 57, 80 952, Gdansk, Poland
    J Math Biol 57:111-37. 2008
    ..Moreover, in the case of stochastic model the bifurcation points vanish and Mayer oscillations in heart period and blood pressure are observed for whole considered space of sympathetic time delays...
  90. ncbi Effects of physical training on cardiovascular control after heart transplantation
    Luciano Bernardi
    Department of Internal Medicine, IRCCS Policlinico S Matteo, University of Pavia, Italy
    Int J Cardiol 118:356-62. 2007
    ..We tested the effects of physical training on baroreceptors-mediated control of heart rate and blood pressure in recently heart-transplanted subjects...
  91. ncbi Effects of long-term vasodilator therapy in patients with carotid sinus hypersensitivity
    M Brignole
    Section of Arrhythmology, Ospedali Riuniti, Lavagna, Italy
    Am Heart J 136:264-8. 1998
    ..In patients affected by carotid sinus hypersensitivity, long-term vasodilator therapy might increase the risk of syncopal episodes by reducing systolic blood pressure and venous return to the heart...
  92. ncbi Enhanced baroreceptor control of the cardiovascular system by polyunsaturated Fatty acids in heart failure patients
    Alberto Radaelli
    Divisione di Riabilitazione Cardiologica, Ospedale San Gerardo, Monza, Italy
    J Am Coll Cardiol 48:1600-6. 2006
    ..The intention of this study was to test the hypothesis that, in heart failure patients, dietary supplementation of polyunsaturated fatty acids (PUFA) enhances arterial baroreceptor control of the cardiovascular system...
  93. ncbi Computational modeling of the baroreflex arc: nucleus tractus solitarius
    R F Rogers
    Central Research and Development, E I du Pont de Nemours and Co, Inc, Wilmington, DE 19880 0328, USA
    Brain Res Bull 51:139-50. 2000
    ..Our results demonstrate that modeling can be a useful tool in analysis of (and examination of underlying mechanisms for) NTS behavior on many levels...
  94. ncbi Arterial pulse pressure and vasopressin release during graded water immersion in humans
    A Gabrielsen
    Danish Aerospace Medical Centre of Research, National University Hospital, Rigshospitalet, Copenhagen, Denmark
    Am J Physiol Regul Integr Comp Physiol 278:R1583-8. 2000
    ..We suggest that when arterial pulse pressure is increased, graded distension of cardiopulmonary receptors modulate AVP release...
  95. ncbi Unloading of baroreceptors by carotid occlusion does not increase heart rate in fetal sheep
    H J Schröder
    Abteilung für experimentelle Medizin, Martinistr 52, 20246, Hamburg, Germany
    Eur J Obstet Gynecol Reprod Biol 92:265-72. 2000
    ..Unloading of baroreceptors by carotid occlusion does not increase heart rate in fetal sheep;..
  96. ncbi A mathematical model for fundamental regulation processes in the cardiovascular system
    F Kappel
    Institut für Mathematik, Universitat Graz, Austria
    J Math Biol 31:611-31. 1993
    ..Simulation results show that the model provides a satisfactory description of data obtained in bicycle ergometer tests...
  97. ncbi Mechano- and chemoreceptor modulation of renal sympathetic nerve activity at birth in fetal sheep
    J L Segar
    Department of Pediatrics and Cardiovascular Center, University of Iowa, Iowa City, Iowa 52242, USA
    Am J Physiol 276:R1295-301. 1999
    ..On the other hand, these peripheral mechanisms appear to be involved in modulating endocrine responses at birth...
  98. ncbi The sensory psychobiology of thirst and salt appetite
    Alan Kim Johnson
    Department of Psychology, University of Iowa, Iowa City, IA 52242 1407, USA
    Med Sci Sports Exerc 39:1388-400. 2007
    ..This information is important for appreciating the extent to which thirst and sodium appetite motivational states and behaviors can be relied on to maintain and repair disruptions of body fluid homeostasis...
  99. ncbi [Baroreflexes originated in vertebral artery zones upon peripheral vein tonus, systemic arterial blood pressure, and external respiration]
    N A Agadzhanian
    Ross Fiziol Zh Im I M Sechenova 94:661-9. 2008
    ..These reflexes of capacity vessels tonic activity changes are part of cardio-respiratory responses of maintaining the tissue gaseous exchange...
  100. doi Hypoventilation during passive leg movement in spinal cord-injured humans
    Hisayoshi Ogata
    Department of Rehabilitation for Movement Functions, Research Institute of National Rehabilitation Center for Persons with Disabilities, 4 1 Namiki, Tokorozawa, Saitama, 359 8555, Japan
    Clin Auton Res 20:101-3. 2010
    ....
  101. ncbi Capsaicin facilitates carotid sinus baroreceptor activity in anesthetized rats
    Hao Zhang
    Department of Physiology, Institute of Basic Medicine, Hebei Medical University, Shijiazhuang, China
    Acta Pharmacol Sin 25:1439-43. 2004
    ..To study the effect of capsaicin on carotid sinus baroreceptor activity (CBA)...

Research Grants110 found, 100 shown here

  1. CONTROLS OF ANTICIPATORY, MEAL-RELATED WATER DRINKING
    THOMAS HOUPT; Fiscal Year: 1990
    ..The control pathway from hypovolemia to increased drinking may include stimulation of pressoreceptors in arteries, large veins and right and left atria...
  2. Neuromechanical basis of baroreceptor function
    John H Schild; Fiscal Year: 2010
    ..The data quantifying the properties of these pressoreceptors and the reflexogenic consequences of BR function and dysfunction are extensive...
  3. Neuromechanical basis of baroreceptor function
    JOHN SCHILD; Fiscal Year: 2009
    ..The data quantifying the properties of these pressoreceptors and the reflexogenic consequences of BR function and dysfunction are extensive...
  4. Arterial baroreceptor unloading causes hypertension
    TERRY THRASHER; Fiscal Year: 2003
    ..These studies will provide a new framework for understanding the development and maintenance of hypertension. ..
  5. Arterial baroreceptor unloading causes hypertension
    TERRY THRASHER; Fiscal Year: 2004
    ..These studies will provide a new framework for understanding the development and maintenance of hypertension. ..
  6. Arterial baroreceptor unloading causes hypertension
    TERRY THRASHER; Fiscal Year: 2002
    ..These studies will provide a new framework for understanding the development and maintenance of hypertension. ..
  7. Arterial baroreceptor unloading causes hypertension
    TERRY THRASHER; Fiscal Year: 2005
    ..These studies will provide a new framework for understanding the development and maintenance of hypertension. ..
  8. BLOOD PRESSURE CONTROL BY FOREBRAIN & BRAINSTEM NEURONS
    SUSAN BARMAN; Fiscal Year: 1991
    ..These studies will enhance our understanding of the central circuitry responsible for generating resting SND in the absence of the effects of anesthesia...
  9. BLOOD PRESSURE CONTROL BY FOREBRAIN & BRAINSTEM NEURONS
    SUSAN BARMAN; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  10. BLOOD PRESSURE CONTROL BY FOREBRAIN & BRAINSTEM NEURONS
    SUSAN BARMAN; Fiscal Year: 1992
    ..These studies will enhance our understanding of the central circuitry responsible for generating resting SND in the absence of the effects of anesthesia...
  11. BLOOD PRESSURE CONTROL BY FOREBRAIN & BRAINSTEM NEURONS
    SUSAN BARMAN; Fiscal Year: 2005
    ..These studies are expected to show that medullary circuits regulating SND are more complexly organized than depicted in most current reviews and that the LTF plays a hitherto unrecognized role in regulating the respiratory rhythm. ..
  12. BLOOD PRESSURE CONTROL BY FOREBRAIN & BRAINSTEM NEURONS
    SUSAN BARMAN; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  13. BLOOD PRESSURE CONTROL BY FOREBRAIN & BRAINSTEM NEURONS
    SUSAN BARMAN; Fiscal Year: 1993
    ..These studies will enhance our understanding of the central circuitry responsible for generating resting SND in the absence of the effects of anesthesia...
  14. BLOOD PRESSURE CONTROL BY FOREBRAIN & BRAINSTEM NEURONS
    SUSAN BARMAN; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  15. BLOOD PRESSURE CONTROL BY FOREBRAIN & BRAINSTEM NEURONS
    SUSAN BARMAN; Fiscal Year: 1990
    ..The electrophysiological techniques to be used include spike-triggered averaging of SND, antidromic mapping and tests for axonal branching, and unit minus or greater than unit crosscorrelation analysis...
  16. CENTRAL NEURAL CONTROL OF CARDIOVASCULAR FUNCTION
    GERARD GEBBER; Fiscal Year: 2000
    ..The above listed hypotheses will be tested by examining the interrelations of these signals using computational methods including spike-triggered averaging, phase plane, ordinary and partial coherence and bicoherence analyses. ..
  17. CENTRAL NEURAL CONTROL OF CARDIOVASCULAR FUNCTION
    GERARD GEBBER; Fiscal Year: 2001
    ..The above listed hypotheses will be tested by examining the interrelations of these signals using computational methods including spike-triggered averaging, phase plane, ordinary and partial coherence and bicoherence analyses. ..
  18. CENTRAL NEURAL CONTROL OF CARDIOVASCULAR FUNCTION
    GERARD GEBBER; Fiscal Year: 2002
    ..The above listed hypotheses will be tested by examining the interrelations of these signals using computational methods including spike-triggered averaging, phase plane, ordinary and partial coherence and bicoherence analyses. ..
  19. CENTRAL NEURAL CONTROL OF CARDIOVASCULAR FUNCTION
    GERARD GEBBER; Fiscal Year: 1999
    ..The above listed hypotheses will be tested by examining the interrelations of these signals using computational methods including spike-triggered averaging, phase plane, ordinary and partial coherence and bicoherence analyses. ..
  20. CENTRAL NEURAL CONTROL OF CARDIOVASCULAR FUNCTION
    GERARD GEBBER; Fiscal Year: 1980
    ....
  21. Regulation of Fetal Myocyte Development
    Jeffrey L Segar; Fiscal Year: 2010
    ....
  22. Circulatory Dysfunction in Chronic Fatigue Syndrome
    Julian Stewart; Fiscal Year: 2003
    ....
  23. Regulation of Fetal Myocyte Development
    JEFFREY SEGAR; Fiscal Year: 2008
    ....
  24. Fetal Cardiac Hypertrophy: Vascular/Metabolic Adaptation
    JEFFREY SEGAR; Fiscal Year: 2003
    ..The end result is hoped to be that the infant with a more 'normal' heart and circulatory physiology will have improved survival with less morbidity. ..
  25. Vascular Dysfunction in CFS
    Julian M Stewart; Fiscal Year: 2010
    ..These may be due to defects in a fundamental signaling molecule called nitric oxide (NO). In the current application we will determine how NO produces POTS in CFS patients and whether drugs that alter NO can improve patient health. ..
  26. Fetal Cardiac Hypertrophy: Vascular/Metabolic Adaptation
    JEFFREY SEGAR; Fiscal Year: 2004
    ..The end result is hoped to be that the infant with a more 'normal' heart and circulatory physiology will have improved survival with less morbidity. ..
  27. Regulation of Fetal Myocyte Development
    JEFFREY SEGAR; Fiscal Year: 2007
    ....
  28. Local Vasoconstriction in Postural Tachycardia Syndrome
    Julian Stewart; Fiscal Year: 2004
    ..Verifying these hypotheses will improve our ability to diagnose and treat an important cause of vascular pathophysiology in man. ..
  29. Local Vasoconstriction in Postural Tachycardia Syndrome
    Julian M Stewart; Fiscal Year: 2010
    ..In the current proposal we will perform sophisticated tests of the circulation and nervous systems to study the causes and mechanisms in these patients and we will test drug treatments. ..
  30. Local Vasoconstriction in Postural Tachycardia Syndrome
    Julian Stewart; Fiscal Year: 2006
    ..Verifying these hypotheses will improve our ability to diagnose and treat an important cause of vascular pathophysiology in man. ..
  31. Local Vasoconstriction in Postural Tachycardia Syndrome
    Julian Stewart; Fiscal Year: 2005
    ..Verifying these hypotheses will improve our ability to diagnose and treat an important cause of vascular pathophysiology in man. ..
  32. Fetal Cardiac Hypertrophy: Vascular/Metabolic Adaptation
    JEFFREY SEGAR; Fiscal Year: 2002
    ..The end result is hoped to be that the infant with a more 'normal' heart and circulatory physiology will have improved survival with less morbidity. ..
  33. Local Vasoconstriction in Postural Tachycardia Syndrome
    Julian Stewart; Fiscal Year: 2007
    ..Verifying these hypotheses will improve our ability to diagnose and treat an important cause of vascular pathophysiology in man. ..
  34. Regulation of Fetal Myocyte Development
    JEFFREY SEGAR; Fiscal Year: 2009
    ....
  35. SYMPATHETIC EXCITATORY RESPONSE AT BIRTH
    JEFFREY SEGAR; Fiscal Year: 2000
    ....
  36. Circulatory Dysfunction in Chronic Fatigue Syndrome
    Julian Stewart; Fiscal Year: 2001
    ....
  37. Local Vasoconstriction in Postural Tachycardia Syndrome
    Julian Stewart; Fiscal Year: 2008
    ..Verifying these hypotheses will improve our ability to diagnose and treat an important cause of vascular pathophysiology in man. ..
  38. Fetal Programming of Coronary Artery Disease
    JEFFREY SEGAR; Fiscal Year: 2005
    ..Only when the causes and mechanisms of hypertension and cardiovascular disease are understood in the context of a developmental process will it be possible to develop strategies for primary prevention. ..
  39. SYMPATHETIC EXCITATORY RESPONSE AT BIRTH
    JEFFREY SEGAR; Fiscal Year: 2001
    ....
  40. Hyperpnea in Orthostatic Intolerance
    Julian Stewart; Fiscal Year: 2008
    ..In the current proposal we will perform sophisticated tests of the circulation and respiration systems to study the causes, mechanisms and potential treatments of upright hyperventilation in POTS. ..
  41. Fetal Cardiac Hypertrophy: Vascular/Metabolic Adaptation
    JEFFREY SEGAR; Fiscal Year: 2001
    ..The end result is hoped to be that the infant with a more 'normal' heart and circulatory physiology will have improved survival with less morbidity. ..
  42. Vascular Dysfunction in CFS
    Julian Stewart; Fiscal Year: 2009
    ..These may be due to defects in a fundamental signaling molecule called nitric oxide (NO). In the current application we will determine how NO produces POTS in CFS patients and whether drugs that alter NO can improve patient health. ..
  43. Circulatory Dysfunction in Chronic Fatigue Syndrome
    Julian Stewart; Fiscal Year: 2002
    ....
  44. Continuation of the Urinary Incontinence Treatment Network (UITN)
    Linda Brubaker; Fiscal Year: 2007
    ..We believe that we can continue to be a productive member of the UITN, with the ultimate objective of improving quality of life for adults through the conduct of high impact clinical research in urinary incontinence. ..
  45. The Stress of Chronic Disease: Mineralocorticoid Mediation of Mood
    Alan Kim Johnson; Fiscal Year: 2011
    ..The proposed experiments will investigate the role of heart failure-induced aldosterone release as a depressivogenic hormonal mechanism. ..
  46. Blood flow and structural adaptation in microcirculation
    TIMOTHY SECOMB; Fiscal Year: 2008
    ..This will be facilitated by well-established and active collaborations with experimental physiologists. ..
  47. Anger Expression, Opioid Dysfunction, and Chronic Pain
    Stephen Bruehl; Fiscal Year: 2008
    ....
  48. Neurovascular Control and Blood Pressure Regulation in Humans
    Michael J Joyner; Fiscal Year: 2010
    ..In summary, this overall approach will permit us to understand how normotensive is maintained in humans with high baseline sympathetic activity and set the stage for understanding how these mechanisms might fail in hypertension. ..
  49. Neurobehavioral Control of Body Fluid Balance in Mouse
    Alan Johnson; Fiscal Year: 2008
    ..heat) challenges. These studies will be especially important for understanding mechanisms underlying pathological conditions such as hypertension and congestive heart failure where excess thirst and sodium intake have been documented. ..
  50. Anger Expression, Opioid Dysfunction, and Chronic Pain
    Stephen Bruehl; Fiscal Year: 2007
    ....
  51. Perfusion of Active Muscles: Metabolites and Nerves
    Michael Joyner; Fiscal Year: 2009
    ..We propose novel and innovative strategies to address a number of currently unresolved issues and controversies related to these topics in humans. ..
  52. Flow regulation and Oxygen transpot in microcirculation
    TIMOTHY SECOMB; Fiscal Year: 2008
    ..Predictions will be compared with experimentally measured distributions in the same vascular networks. ..
  53. Flow regulation and oxygen transport in microcirculation
    TIMOTHY SECOMB; Fiscal Year: 2003
    ..This will be facilitated by the investigator's longstanding and close collaboration with experimental physiologists. ..
  54. Arterial Baroreflex Control of Blood Pressure (Exercise)
    Peter Raven; Fiscal Year: 2003
    ..These findings will have implications for the care of patients suffering from non-insulin dependent diabetes mellitus (NIDDM), hypertension and cardiac failure. ..
  55. Estrogen and Sympathetically Mediated Vasoconstriction
    PAUL FADEL; Fiscal Year: 2004
    ..abstract_text> ..
  56. Psychobiological Mechanisms of Stress & Smoking Relapse
    MUSTAFA AL ABSI; Fiscal Year: 2003
    ..Reducing relapse rates will contribute significantly towards decreasing tobacco use and its devastating effects. ..
  57. MICROVASCULAR BLOOD RHEOLOGY & RED BLOOD CELL MECHANICS
    TIMOTHY SECOMB; Fiscal Year: 2000
    ..This will be facilitated by well-established and active collaborations with experimental hemorheologists and physiologists. ..
  58. NEUROPEPTIDES AND CARDIOVASCULAR REGULATION
    VIRGINIA BROOKS; Fiscal Year: 2000
    ....
  59. Muscle Mechanosensitivity in Heart Failure
    Holly Middlekauff; Fiscal Year: 2004
    ..After a 4 week conditioning program, which reverses the myopathy of HF, the above testing repeated to determine if the muscle mechanoreceptor sensitization is reversible. ..
  60. BIOBEHAVIORAL FACTORS IN ATHEROSCLEROTIC PROGRESSION
    Thomas Kamarck; Fiscal Year: 1999
    ..These recent measurement innovations, as employed in the present study, should significantly enhance our current understanding of the role of behavioral processes in coronary heart disease risk. ..
  61. Perfusion of Active Muscles: Metabolites and Nerves
    Michael Joyner; Fiscal Year: 2004
    ..abstract_text> ..
  62. PERFUSION OF ACTIVE MUSCLES--METABOLITES AND NERVES
    Michael Joyner; Fiscal Year: 2001
    ..These vasodilating mechanisms may have significance in a variety of disease states associated with endothelial and autonomic dysfunction. ..
  63. NEUROPEPTIDES AND CARDIOVASCULAR REGULATION
    VIRGINIA BROOKS; Fiscal Year: 2001
    ....
  64. Patient-Oriented Models for Urinary Function in Women
    Linda Brubaker; Fiscal Year: 2008
    ..unreadable] b. To model urinary storage in health and disease [unreadable] c. To model urinary emptying in health and diseas [unreadable] [unreadable]..
  65. Neurobehavioral Control of Body Fluid Balance in Mouse
    Alan Johnson; Fiscal Year: 2009
    ..heat) challenges. These studies will be especially important for understanding mechanisms underlying pathological conditions such as hypertension and congestive heart failure where excess thirst and sodium intake have been documented. ..
  66. CARDIAC AND ARTERIAL BAROREFLEXES IN HEART FAILURE
    Irving Zucker; Fiscal Year: 1991
    ..This 5-year program represents a multidisciplinary approach to investigate the reflex abnormalities which may contribute to the symptomatology of chronic heart failure...
  67. CARDIOPULMONARY REFLEXES IN HEART FAILURE
    Irving Zucker; Fiscal Year: 1992
    ..Mechanical stimuli will include ascending aortic and vena caval occlusions. Chemical stimuli will include intracoronary and topical application of prostaglandins, arachidonic acid and bradykinin...
  68. NO AND EXERCISE VASODILATION IN HUMAN HYPERLIPIDEMIA
    Michael Joyner; Fiscal Year: 2001
    ..Data from these patient- oriented studies have implications related to understanding the contribution of endothelial function in a variety of common diseases. ..
  69. Pain Regulatory Dysfunction in Chronic Pain
    Stephen Bruehl; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  70. PHARMACOLOGIC PROBES IN NEURALLY-MEDIATED SYNCOPE
    Italo Biaggioni; Fiscal Year: 2003
    ..These studies will be directly applicable to the evaluation and treatment of patients with these incapacitating disorders. ..
  71. Limb Neurovascular Control and Aging
    KEVIN MONAHAN; Fiscal Year: 2007
    ..3) The mechanisms underlying age- and limb-related differences in [NE]i involve modulators of synaptic norepinephrine levels (uptake 1), but not presynaptic alpha-2 adrenergic modulation of NE release. ..
  72. Neuronal Mechanisms of Opioid Action
    Hong Zhu; Fiscal Year: 2004
    ..These experiments will improve our understanding of neuronal mechanisms of opioid action, which is crucial for understanding and perhaps treating of opioid addiction. ..
  73. NO AND EXERCISE VASODILATION IN HUMAN HYPERLIPIDEMIA
    Michael Joyner; Fiscal Year: 2004
    ..Data from these patient- oriented studies have implications related to understanding the contribution of endothelial function in a variety of common diseases. ..
  74. Neurobehavioral Control of Body Fluid Balance in Mouse
    Alan Johnson; Fiscal Year: 2007
    ..heat) challenges. These studies will be especially important for understanding mechanisms underlying pathological conditions such as hypertension and congestive heart failure where excess thirst and sodium intake have been documented. ..
  75. Neurovascular Control and Blood Pressure Regulation in Humans
    Michael Joyner; Fiscal Year: 2009
    ..In summary, this overall approach will permit us to understand how normotensive is maintained in humans with high baseline sympathetic activity and set the stage for understanding how these mechanisms might fail in hypertension. ..
  76. The Renal Medulla and Hypertension
    David Stec; Fiscal Year: 2009
    ..A better understanding of the how the kidney controls blood pressure may provide an opportunity to develop new drugs to treat people with hypertension who are resistant to current therapies. ..