recurrent laryngeal nerve

Summary

Summary: Branches of the vagus (tenth cranial) nerve. The recurrent laryngeal nerves originate more caudally than the superior laryngeal nerves and follow different paths on the right and left sides. They carry efferents to all muscles of the larynx except the cricothyroid and carry sensory and autonomic fibers to the laryngeal, pharyngeal, tracheal, and cardiac regions.

Top Publications

  1. pmc Laryngeal recurrent nerve injury in surgery for benign thyroid diseases: effect of nerve dissection and impact of individual surgeon in more than 27,000 nerves at risk
    Michael Hermann
    Department of Surgery, Kaiserin Elisabeth Spital, University of Vienna, Vienna, Austria
    Ann Surg 235:261-8. 2002
  2. ncbi Electrophysiologic recurrent laryngeal nerve monitoring during thyroid and parathyroid surgery: international standards guideline statement
    Gregory W Randolph
    Department of Otology and Laryngology, Division of Thyroid and Parathyroid Surgery, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Laryngoscope 121:S1-16. 2011
  3. ncbi The mechanism of recurrent laryngeal nerve injury during thyroid surgery--the application of intraoperative neuromonitoring
    Feng Yu Chiang
    Department of Otolaryngology Head and Neck Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Surgery 143:743-9. 2008
  4. ncbi Standardization of intraoperative neuromonitoring of recurrent laryngeal nerve in thyroid operation
    Feng Yu Chiang
    Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Kaohsiung Medical University, No 100, Tzyou First Road, Kaohsiung City, 807, Taiwan
    World J Surg 34:223-9. 2010
  5. ncbi Intraoperative recurrent laryngeal nerve monitoring in thyroid surgery: is it really useful?
    P G Calò
    Departments of Surgical Sciences, and School of Specialty in Forensic Medicine, and Public Health, Clinical and Molecular Medicine, University of Cagliari, Italy
    Clin Ter 164:e193-8. 2013
  6. ncbi Intraoperative monitoring of the recurrent laryngeal nerve in thyroid surgery
    H Dralle
    Department of General, Visceral and Vascular Surgery, Martin Luther University of Halle, Ernst Grube Str 40, D 06097 Halle Saale, Germany
    World J Surg 32:1358-66. 2008
  7. ncbi Intraoperative electromyographic monitoring of the recurrent laryngeal nerve in reoperative thyroid and parathyroid surgery
    Donald E Yarbrough
    Department of Surgery, College of Medicine, Mayo Clinic, Mayo Building W6, 200 First Street SW, Rochester, MN 55905, USA
    Surgery 136:1107-15. 2004
  8. ncbi Anatomy of right recurrent nerve node: why does early metastasis of esophageal cancer occur in it?
    Masaomi Mizutani
    Department of Gastroenterological Surgery, Yamagata University School of Medicine, 2 2 2 Iidanishi, Yamagata 990 9585, Japan
    Surg Radiol Anat 28:333-8. 2006
  9. ncbi Pitfalls of intraoperative neuromonitoring for predicting postoperative recurrent laryngeal nerve function during thyroidectomy
    Wai Fan Chan
    Division of Endocrine Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Pokfulam, Hong Kong, China
    World J Surg 30:806-12. 2006
  10. ncbi Anatomical variations of recurrent laryngeal nerve during thyroid surgery: how to identify and handle the variations with intraoperative neuromonitoring
    Feng Yu Chiang
    Department of Otolaryngology, Kaohsiung Medical University Hospital, Taiwan
    Kaohsiung J Med Sci 26:575-83. 2010

Research Grants

Detail Information

Publications272 found, 100 shown here

  1. pmc Laryngeal recurrent nerve injury in surgery for benign thyroid diseases: effect of nerve dissection and impact of individual surgeon in more than 27,000 nerves at risk
    Michael Hermann
    Department of Surgery, Kaiserin Elisabeth Spital, University of Vienna, Vienna, Austria
    Ann Surg 235:261-8. 2002
    To evaluate the effect of recurrent nerve dissection on the incidence of recurrent laryngeal nerve injury (RLNI) and to analyze the performance of individual surgeons.
  2. ncbi Electrophysiologic recurrent laryngeal nerve monitoring during thyroid and parathyroid surgery: international standards guideline statement
    Gregory W Randolph
    Department of Otology and Laryngology, Division of Thyroid and Parathyroid Surgery, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Laryngoscope 121:S1-16. 2011
    ..We hope this work will minimize inappropriate variations in monitoring rather than to dictate practice options...
  3. ncbi The mechanism of recurrent laryngeal nerve injury during thyroid surgery--the application of intraoperative neuromonitoring
    Feng Yu Chiang
    Department of Otolaryngology Head and Neck Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Surgery 143:743-9. 2008
    Identification of recurrent laryngeal nerve (RLN) has decreased the rates of permanent RLN palsy during thyroid operations; however, unexpected RLN palsy still occurs, even though the visual integrity was assured and most nerve injuries ..
  4. ncbi Standardization of intraoperative neuromonitoring of recurrent laryngeal nerve in thyroid operation
    Feng Yu Chiang
    Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Municipal Hsiao Kang Hospital, Kaohsiung Medical University, No 100, Tzyou First Road, Kaohsiung City, 807, Taiwan
    World J Surg 34:223-9. 2010
    ..may lead to highly variable results, and many of these results can cause misleading information and, conversely, increase the risk of recurrent laryngeal nerve (RLN) injury. Therefore, standardization of IONM procedures is necessary.
  5. ncbi Intraoperative recurrent laryngeal nerve monitoring in thyroid surgery: is it really useful?
    P G Calò
    Departments of Surgical Sciences, and School of Specialty in Forensic Medicine, and Public Health, Clinical and Molecular Medicine, University of Cagliari, Italy
    Clin Ter 164:e193-8. 2013
    The aim of this study was to evaluate the ability of intraoperative recurrent laryngeal nerve monitoring to predict the postoperative functional outcome and the potential role of this technique in reducing the postoperative nerve palsy ..
  6. ncbi Intraoperative monitoring of the recurrent laryngeal nerve in thyroid surgery
    H Dralle
    Department of General, Visceral and Vascular Surgery, Martin Luther University of Halle, Ernst Grube Str 40, D 06097 Halle Saale, Germany
    World J Surg 32:1358-66. 2008
    b>Recurrent laryngeal nerve (RLN) palsy ranks among the leading reasons for medicolegal litigation of surgeons because of its attendant reduction in quality of life...
  7. ncbi Intraoperative electromyographic monitoring of the recurrent laryngeal nerve in reoperative thyroid and parathyroid surgery
    Donald E Yarbrough
    Department of Surgery, College of Medicine, Mayo Clinic, Mayo Building W6, 200 First Street SW, Rochester, MN 55905, USA
    Surgery 136:1107-15. 2004
    Injury to the recurrent laryngeal nerve (RLN) is a rare complication of initial thyroid and parathyroid surgery, but the prevalence is much higher in the reoperative setting...
  8. ncbi Anatomy of right recurrent nerve node: why does early metastasis of esophageal cancer occur in it?
    Masaomi Mizutani
    Department of Gastroenterological Surgery, Yamagata University School of Medicine, 2 2 2 Iidanishi, Yamagata 990 9585, Japan
    Surg Radiol Anat 28:333-8. 2006
    ..However, the collateral of the recR and its direct drainage to the venous system suggested that the recR involvement often corresponds to a systemic disease...
  9. ncbi Pitfalls of intraoperative neuromonitoring for predicting postoperative recurrent laryngeal nerve function during thyroidectomy
    Wai Fan Chan
    Division of Endocrine Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Pokfulam, Hong Kong, China
    World J Surg 30:806-12. 2006
    ..neuromonitoring has been widely adopted to facilitate the identification and preservation of recurrent laryngeal nerve (RLN) function during thyroid surgery...
  10. ncbi Anatomical variations of recurrent laryngeal nerve during thyroid surgery: how to identify and handle the variations with intraoperative neuromonitoring
    Feng Yu Chiang
    Department of Otolaryngology, Kaohsiung Medical University Hospital, Taiwan
    Kaohsiung J Med Sci 26:575-83. 2010
    b>Recurrent laryngeal nerve (RLN) palsy is the most common and serious complication after thyroid surgery...
  11. ncbi Incidence of vocal cord paralysis with and without recurrent laryngeal nerve monitoring during thyroidectomy
    Maisie Shindo
    Division of Otolaryngology Head and Neck Surgery, School of Medicine, State University of New York at Stony Brook, NY 11794 8191, USA
    Arch Otolaryngol Head Neck Surg 133:481-5. 2007
    ..paresis or paralysis in a cohort of patients who underwent thyroidectomy with and without continuous recurrent laryngeal nerve (RLN) monitoring by a single senior surgeon...
  12. ncbi Recurrent laryngeal nerve monitoring versus identification alone on post-thyroidectomy true vocal fold palsy: a meta-analysis
    Thomas S Higgins
    Department of Otolaryngology Head and Neck Surgery, Eastern Virginia Medical School, Norfolk, Virginia 23507, USA
    Laryngoscope 121:1009-17. 2011
    To compare by meta-analysis the effect of recurrent laryngeal nerve (RLN) monitoring versus RLN identification alone on true vocal fold palsy rates after thyroidectomy.
  13. ncbi Role of intraoperative neuromonitoring of the recurrent laryngeal nerve in high-risk thyroid surgery
    Ihab Atallah
    Department of Otolaryngology and Head and Neck Surgery, Hautepierre Hospital, Strasbourg, France
    J Otolaryngol Head Neck Surg 38:613-8. 2009
    Thyroid surgeries associated with an elevated incidence of recurrent laryngeal nerve (RLN) injury are considered high-risk thyroidectomies...
  14. ncbi Recurrent laryngeal nerve paralysis: anatomy and etiology
    David Myssiorek
    Department of Otolaryngology and Communicative Disorders, The Long Island Jewish Medical Center, The Long Island Campus of the Albert Einstein College of Medicine, 270 05 76th Avenue, Suite 1120, New Hyde Park, NY 11040, USA
    Otolaryngol Clin North Am 37:25-44, v. 2004
    ..Recovery is dependent on the type, extent, and site of nerve lesion. Familiarity with this data allows the otolaryngologist to tailor management to suit each patient with vocal fold paralysis...
  15. ncbi Elucidating mechanisms of recurrent laryngeal nerve injury during thyroidectomy and parathyroidectomy
    Samuel K Snyder
    Department of Surgery, Scott and White Memorial Hospital, Temple, TX 76508, USA
    J Am Coll Surg 206:123-30. 2008
    ..parathyroidectomy, or related central neck procedures can elucidate actual or potential mechanisms of recurrent laryngeal nerve (RLN) injury, especially visually intact nerves, which were previously unknown to the endocrine surgeon.
  16. ncbi Advantages of recurrent laryngeal nerve identification in thyroidectomy and parathyroidectomy and the importance of preoperative and postoperative laryngoscopic examination in more than 1000 nerves at risk
    Martin Steurer
    Department of Otorhinolaryngology Head and Neck Surgery, Vienna Medical School, General Hospital Vienna, Waeringer Guertel 18 20, A 1090 Vienna, Austria
    Laryngoscope 112:124-33. 2002
    b>Recurrent laryngeal nerve palsy (RLNP) is a major obstacle in thyroid and parathyroid surgery. Therefore, methods that reduce the number of temporary and, especially, permanent recurrent laryngeal nerve palsies are of great interest...
  17. ncbi Topography of the recurrent laryngeal nerve in relation to the thyroid artery, Zuckerkandl tubercle, and Berry ligament in Kenyans
    W Kaisha
    Department of Human Anatomy, University of Nairobi, Nairobi, Kenya
    Clin Anat 24:853-7. 2011
    Injury to the recurrent laryngeal nerve (RLN) is an important but avoidable complication of thyroidectomy. This complication may be avoided by the identification of the nerve facilitated by important landmarks found along its course...
  18. ncbi The Zuckerkandl's tubercle: a useful anatomical landmark for detecting both the recurrent laryngeal nerve and the superior parathyroid during thyroid surgery
    Ji Sup Yun
    Department of Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
    Endocr J 55:925-30. 2008
    ..This study evaluated ZT anatomical characteristics in terms of the recurrent laryngeal nerve (RLN) and the superior parathyroid (SP)...
  19. ncbi Monitoring of the recurrent laryngeal nerve in totally endoscopic thyroid surgery
    K Witzel
    Minimal Invasiv Center, Huenfeld, Germany
    Eur Surg Res 43:72-6. 2009
    ..the feasibility of the sublingual transoral access for thyroid resection including the monitoring of the recurrent laryngeal nerve (RLN) in a porcine model...
  20. ncbi The role of intraoperative neuromonitoring of recurrent laryngeal nerve during thyroidectomy: a comparative study on 1000 nerves at risk
    Wai Fan Chan
    Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Surgery 140:866-72; discussion 872-3. 2006
    The role of intraoperative neuromonitoring of recurrent laryngeal nerve (RLN) during thyroidectomy has not been well established...
  21. ncbi Risk factors of paralysis and functional outcome after recurrent laryngeal nerve monitoring in thyroid surgery
    Henning Dralle
    Department of General, Visceral and Vascular Surgery, Klinikum Kröllwitz, University of Halle, Ernst Grube Strasse 40, D 06097 Halle, Germany
    Surgery 136:1310-22. 2004
    b>Recurrent laryngeal nerve monitoring (RLNM) has been suspected to reduce postoperative RLN paralysis (RLNP)...
  22. ncbi Recurrent laryngeal nerve in thyroid surgery: a critical appraisal
    Abdullah N Hisham
    Department of Breast and Endocrine Surgery, Putrajaya Hospital, Malaysia
    ANZ J Surg 72:887-9. 2002
    Identification and preservation of the recurrent laryngeal nerve (RLN) is of major concern in surgery of the thyroid gland...
  23. ncbi Extralaryngeal bifurcation of the recurrent laryngeal nerve: a common variation
    Tilan Beneragama
    Breast, Endocrine Surgery and Surgical Oncology Unit and Monash University, Frankston Hospital, Melbourne, Victoria, Australia
    ANZ J Surg 76:928-31. 2006
    Extralaryngeal bifurcation and trifurcation of the recurrent laryngeal nerve (RLN) is not well described in anatomical texts...
  24. ncbi The motor fibers of the recurrent laryngeal nerve are located in the anterior extralaryngeal branch
    Jonathan W Serpell
    Endocrine Surgery Unit, Monash University, The Alfred Hospital, Melbourne, Australia
    Ann Surg 249:648-52. 2009
    This study aimed to establish the prevalence of extralaryngeal bifurcation of the recurrent laryngeal nerve (RLN) and investigate the location of the motor fibers to the intrinsic muscles of the larynx within the branches of the RLN.
  25. ncbi Effects of long-term denervation on the rat thyroarytenoid muscle
    Satoru Miyamaru
    Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kumamoto University, Honjo, Kumamoto, Japan
    Laryngoscope 118:1318-23. 2008
    ..To determine the effects of long-term denervation on the rat thyroarytenoid (TA) muscle and neuromuscular junctions...
  26. ncbi Prospective study on loss of signal on the first side during neuromonitoring of the recurrent laryngeal nerve in total thyroidectomy
    A Sitges-Serra
    Endocrine Surgery Unit, Hospital del Mar, Barcelona, Spain
    Br J Surg 100:662-6. 2013
    ..loss of the signal from intraoperative nerve monitoring is observed after first-side dissection of the recurrent laryngeal nerve. There is no high-quality evidence supporting this recommendation...
  27. ncbi Nimodipine improves reinnervation and neuromuscular function after injury to the recurrent laryngeal nerve in the rat
    Jonas Hydman
    Department of Clinical Neuroscience, Section of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden
    Ann Otol Rhinol Laryngol 116:623-30. 2007
    Injury of the recurrent laryngeal nerve (RLN) is associated with a high degree of neuronal survival, but leads to various levels of vocal fold motion impairment or laryngeal synkinesis, which has been attributed to misdirected ..
  28. ncbi Recurrent laryngeal nerve electrophysiologic monitoring in thyroid surgery: the standard of care?
    Robert L Witt
    The Devon, Wilmington, DE 19806, USA
    J Voice 19:497-500. 2005
    ..Electrophysiologic RLN integrity does not always translate into clinical postoperative vocal fold mobility. Electrophysiologic RLN monitoring may support that the RLN was not severed in the patient with postoperative VFI...
  29. ncbi Neuronal survival and glial reactions after recurrent laryngeal nerve resection in the rat
    J Hydman
    Department of Clinical Neuroscience, Section of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden
    Laryngoscope 115:619-24. 2005
    Complete axonal injury to the recurrent laryngeal nerve (RLN) leads to permanent loss of coordinated function of the intrinsic muscles of the larynx...
  30. ncbi Evaluation of recurrent laryngeal nerve monitoring in thyroid surgery
    Serkan Sari
    Istanbul University, Istanbul Medical Faculty, Department of General Surgery, 34093 Capa, Istanbul, Turkey
    Int J Surg 8:474-8. 2010
    ..Intraoperative nerve monitoring (IONM) has been used as an adjunct to the visual identification of the nerve. The aim of this clinical trial is to evaluate the effect of the identification time of RLN during thyroidectomy using IONM...
  31. ncbi Recurrent laryngeal nerve injury: an experience with 310 thyroidectomies
    Ishtiaq Ahmed Chaudhary
    Department of Surgery, Foundation University Medical College, Rawalpindi
    J Ayub Med Coll Abbottabad 19:46-50. 2007
    ..This study was designed to determine the prevalence of recurrent laryngeal nerve (RLN) injury and duration of recovery following transient recurrent laryngeal nerve injury, during ..
  32. ncbi Using MR imaging to predict invasion of the recurrent laryngeal nerve by thyroid carcinoma
    Shodayu Takashima
    Department of Radiology, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    AJR Am J Roentgenol 180:837-42. 2003
    We evaluated the accuracy of MR imaging findings for predicting invasion of the recurrent laryngeal nerve by thyroid carcinoma and established an optimal criterion on which to base this prediction.
  33. ncbi Lymphadenectomy along the left recurrent laryngeal nerve by a minimally invasive esophagectomy in the prone position for thoracic esophageal cancer
    Hirokazu Noshiro
    Department of Surgery, Faculty of Medicine, Saga University, 5 1 1 Nabeshima, Saga, 849 8501, Japan
    Surg Endosc 24:2965-73. 2010
    ..However, the efficacy of the prone position in an aggressive thoracoscopic esophagectomy with an extensive lymphadenectomy has not been fully documented...
  34. ncbi History of the recurrent laryngeal nerve: from Galen to Lahey
    Edwin L Kaplan
    Department of Surgery, Section of General Surgery, University of Chicago Pritzker School of Medicine, 5841 S Maryland Avenue, MC4052, Chicago, IL 60637, USA
    World J Surg 33:386-93. 2009
    ..Demonstrating before the elders of Rome, he showed that cutting the recurrent laryngeal nerve in the neck caused a live pig to stop squealing-an extraordinary feat...
  35. ncbi Recurrent laryngeal nerve palsy after thyroidectomy with routine identification of the recurrent laryngeal nerve
    Feng Yu Chiang
    Department of Otolaryngology Head and Neck Surgery, Kaohsiung Medical University, Chung Ho Memorial Hospital, Kaohsiung, Taiwan
    Surgery 137:342-7. 2005
    The aim of this study was to assess the risk of recurrent laryngeal nerve palsy (RLNP) after thyroidectomy with routine identification of the recurrent laryngeal nerve (RLN) during the operation.
  36. ncbi Does extensive dissection of recurrent laryngeal nerve during thyroid operation increase the risk of nerve injury? Evidence from the application of intraoperative neuromonitoring
    Feng Yu Chiang
    Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Taiwan
    Am J Otolaryngol 32:499-503. 2011
    Extensive dissection of recurrent laryngeal nerve (RLN) is inevitable in some complicated thyroid operations. The study aimed to determine whether extensive dissection of RLN increases the risk of nerve injury.
  37. ncbi Intraoperative neuromonitoring for early localization and identification of recurrent laryngeal nerve during thyroid surgery
    Feng Yu Chiang
    Department of Otolaryngology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Kaohsiung J Med Sci 26:633-9. 2010
    Early and definite identification of the recurrent laryngeal nerve (RLN) is an important step to avoid inadvertent nerve injury during complicated thyroid operations...
  38. ncbi Voice changes after thyroidectomy without recurrent laryngeal nerve injury
    Diego L Sinagra
    Division of Surgical Oncology, Hospital de Clinicas Jose de San Martin, University of Buenos Aires, Buenos Aires, Argentina
    J Am Coll Surg 199:556-60. 2004
    ..We describe voice changes after total thyroidectomy, without inferior laryngeal nerve injury, using a computer program to objectively compare different patterns of voice...
  39. ncbi Malpractice litigation after thyroid surgery: the role of recurrent laryngeal nerve injuries, 1989-2009
    Shabirhusain S Abadin
    Department of Surgery, St Joseph Hospital, Chicago, IL 60657, USA
    Surgery 148:718-22; discussion 722-3. 2010
    b>Recurrent laryngeal nerve injuries remain a complication that is a source of concern to both surgeons and patients...
  40. ncbi Recurrent laryngeal nerve monitoring: state of the art, ethical and legal issues
    Peter Angelos
    Section of General Surgery and Surgical Oncology, MacLean Center for Clinical Medical Ethics, University of Chicago, Chicago, IL 60637, USA
    Surg Clin North Am 89:1157-69. 2009
    Despite many advances in surgical techniques during the last several decades, the risk for recurrent laryngeal nerve (RLN) injury during thyroid and parathyroid surgery has only declined, not disappeared...
  41. ncbi First experiences in intraoperative neurostimulation of the recurrent laryngeal nerve during thyroid surgery of children and adolescents
    Michael Brauckhoff
    Department of General, Visceral, and Vascular Surgery, Martin Luther University Halle Wittenberg, Halle Saale, Germany
    J Pediatr Surg 37:1414-8. 2002
    Intraoperative neurostimulation of the recurrent laryngeal nerve may reduce nerve palsy during thyroid surgery and is well established in adults...
  42. ncbi Spontaneous regeneration of recurrent laryngeal nerve following long-term vocal fold paralysis in humans: histologic evidence
    Donghui Chen
    Institute of Biomedical Engineering, Second Military Medical University, Shanghai, China
    Laryngoscope 121:1035-9. 2011
    To validate the occurrence of spontaneous regeneration of the recurrent laryngeal nerve (RLN) in patients with symptomatic vocal fold paralysis (VFP).
  43. ncbi Electrophysiologic monitoring characteristics of the recurrent laryngeal nerve preoperatively paralyzed or invaded with malignancy
    Dipti Kamani
    Massachusetts Eye and Ear Infirmary, Division of Thyroid and Parathyroid Surgery, Harvard Medical School, Boston, Massachusetts, USA
    Otolaryngol Head Neck Surg 149:682-8. 2013
    ....
  44. ncbi Should an involved but functioning recurrent laryngeal nerve be shaved or resected in a locally advanced papillary thyroid carcinoma?
    Brian Hung Hin Lang
    Division of Endocrine Surgery, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong SAR
    Ann Surg Oncol 20:2951-7. 2013
    The issue of whether an involved but functioning recurrent laryngeal nerve (RLN) should be shaved or resected in locally advanced papillary thyroid carcinoma (PTC) remains controversial...
  45. ncbi Recurrent laryngeal nerve paralysis in patients with papillary thyroid carcinomas: evaluation and management of resulting vocal dysfunction
    Jong Lyel Roh
    Department of Otolaryngology, Asan Medical Centre, University of Ulsan, College of Medicine, Songpa Gu, Seoul, Republic of Korea
    Am J Surg 197:459-65. 2009
    b>Recurrent laryngeal nerve paralysis (RLNP) occurs in patients with thyroid malignancy. This study prospectively evaluated vocal function and management outcomes of patients with papillary thyroid carcinomas (PTCs) and RLNP.
  46. ncbi Sensitivity and specificity of intraoperative recurrent laryngeal nerve stimulation test for predicting vocal cord palsy after thyroid surgery
    Chisato Tomoda
    Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe, 650 0011, Japan
    World J Surg 30:1230-3. 2006
    b>Recurrent laryngeal nerve (RLN) palsy after thyroidectomy, although infrequently encountered, can decrease quality of life...
  47. ncbi GlideScope-assisted nerve integrity monitoring tube placement for intra-operative recurrent laryngeal nerve monitoring
    S P Kanotra
    Center for Thyroid and Parathyroid Surgery, Department of Otolaryngology Head and Neck Surgery, St Luke s Roosevelt Hospital Center, New York, New York, USA
    J Laryngol Otol 126:1271-3. 2012
    The proper positioning of the Nerve Integrity Monitoring® endotracheal tube during recurrent laryngeal nerve monitoring is of paramount importance...
  48. ncbi Effect of approach side during anterior cervical discectomy and fusion on the incidence of recurrent laryngeal nerve injury
    Craig Kilburg
    Department of Neurosurgery, Gundersen Lutheran Medical Center, Gundersen Lutheran Medical Foundation, La Crosse, Wisconsin 54601, USA
    J Neurosurg Spine 4:273-7. 2006
    ..whether side of approach during instrumented, one- or two-level primary anterior cervical discectomy and fusion (ACDF) affects the incidence of recurrent laryngeal nerve (RLN) injury diagnosed by observation of the vocal cords (OVC).
  49. ncbi Outcome of vocal cord function after partial layer resection of the recurrent laryngeal nerve in patients with invasive papillary thyroid cancer
    Minoru Kihara
    Department of Surgery, Kuma Hospital, Kobe, Japan Electronic address
    Surgery 155:184-9. 2014
    The recurrent laryngeal nerve (RLN) may be involved by thyroid cancer even in patients with functioning vocal cords preoperatively. In such cases, we try to preserve the nerve with sharp dissection...
  50. ncbi Prognosis and prognostic factors of patients with papillary thyroid carcinoma requiring resection of recurrent laryngeal nerve due to carcinoma extension
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Kobe 650 0011, Japan
    Endocr J 59:247-52. 2012
    The recurrent laryngeal nerve (RN) is one of the most common organs to which papillary thyroid carcinoma (PTC) extends. However, the prognosis and prognostic factors for patients with PTC extending to the RN remain unclear...
  51. ncbi Delivery of an adenoviral vector to the crushed recurrent laryngeal nerve
    Adam Rubin
    Department of Otorhinolaryngology, University of Michigan, Ann Arbor, USA
    Laryngoscope 113:985-9. 2003
    Objectives were to create a model of recurrent laryngeal nerve injury for testing the efficacy of potential therapeutic viral gene therapy vectors and to demonstrate that remote injection of a viral vector does not cause significant ..
  52. ncbi Variability in nerve patterns of the adductor muscle group supplied by the recurrent laryngeal nerve
    Eva Maranillo
    Department of Anatomy and Human Embryology, Faculty of Medicine, Complutense University of Madrid, Madrid 28040, Spain
    Laryngoscope 115:358-62. 2005
    ..The aim of the present work was to study the nerve supply of the adductor laryngeal muscles supplied by the recurrent laryngeal nerve.
  53. ncbi A newly identified variation at the entry of the recurrent laryngeal nerve into the larynx
    Tanglei Shao
    Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    J Invest Surg 23:314-20. 2010
    We aimed to highlight a new anatomical variation of the recurrent laryngeal nerve (RLN), and to emphasize its implications for thyroid surgery.
  54. ncbi Recurrent laryngeal nerve: significance of the anterior extralaryngeal branch
    Emad Kandil
    Department of Surgery, Tulane University, School of Medicine, New Orleans, LA
    Surgery 149:820-4. 2011
    Recognition of extralaryngeal branching of the recurrent laryngeal nerve (RLN) is crucial, because inadvertent operative division may lead to significant postoperative morbidity...
  55. ncbi Recurrent laryngeal nerve damage and phonetic modifications after total thyroidectomy: surgical malpractice only or predictable sequence?
    Lodovico Rosato
    Department of Surgery, Endocrine Surgical Unit, Ivrea Hospital, Piazza della Credenza, Ivrea, 2 10015, Italy
    World J Surg 29:780-4. 2005
    ..dysphagia: 4 (2%) monoplegia and 12 (6%) hypomobility of the vocal cords due to impaired function of the recurrent laryngeal nerve (RLN); 6 (3%) cord hypotonia due to impairment of the superior laryngeal nerve (SLN); 34 (16%) dysphagia:..
  56. ncbi Does extralaryngeal branching have an impact on the rate of postoperative transient or permanent recurrent laryngeal nerve palsy?
    Claudio Casella
    Department of General Surgery, University of Brescia School of Medicine, Brescia, Italy
    World J Surg 33:261-5. 2009
    This prospective study assessed the prevalence of the extralaryngeal branching of the recurrent laryngeal nerve (RLN) and its impact on the incidence of postoperative transient or permanent RLN palsy.
  57. ncbi Remote delivery of rAAV-GFP to the rat brainstem through the recurrent laryngeal nerve
    A D Rubin
    Department of Neurology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Laryngoscope 111:2041-5. 2001
    To demonstrate that a recombinant adeno-associated viral vector (rAAV) carrying the gene for green fluorescent protein (GFP) could be delivered to the rat brainstem by remote injection into the recurrent laryngeal nerve.
  58. ncbi Real-time monitoring of the recurrent laryngeal nerve: an observational clinical trial
    Christoph Ulmer
    Department of General, Visceral, and Trauma Surgery, Robert Bosch Hospital, Stuttgart, Germany
    Surgery 143:359-65. 2008
    ..intermittent electrophysiological tracing of the nerves, but its use is still associated with permanent recurrent laryngeal nerve (RLN) injury...
  59. ncbi Improvement in phonation after reconstruction of the recurrent laryngeal nerve in patients with thyroid cancer invading the nerve
    Akira Miyauchi
    Department of Surgery, Kuma Hospital, Kobe, Japan
    Surgery 146:1056-62. 2009
    We report vocal improvement after reconstruction of the recurrent laryngeal nerve (RLN) in patients with nerve resection, although vocal cord movement was not restored. These methods are not widely recognized.
  60. ncbi Surgical anatomy of the recurrent laryngeal nerve revisited
    Maisie L Shindo
    Division of Otolaryngology Head and Neck Surgery, SUNY at Stony Brook, Stony Brook, NY 11794, USA
    Otolaryngol Head Neck Surg 133:514-9. 2005
    ..The surgical topographical anatomy of the nerve in this region has not been studied in detail, which is the focus of this study...
  61. ncbi Recurrent laryngeal nerve post-natal development in rats
    Nara Terezinha Montali Silva Lima
    Department of Ophthalmology and Otolaryngology, Medical School of Ribeirao Preto, University of Sao Paulo, 14049 900, Ribeirao Preto, Sao Paulo, Brazil
    J Neurosci Methods 165:18-24. 2007
    Studies on the normal pattern of development and post-natal maturation of the recurrent laryngeal nerve in rats are scanty...
  62. ncbi Clinically relevant anatomy of recurrent laryngeal nerve
    Justin M Haller
    Department of Orthopaedic Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA
    Spine (Phila Pa 1976) 37:97-100. 2012
    ..An anatomic study of anterior cervical dissection of 11 embalmed cadavers...
  63. ncbi Palpatory method used to identify the recurrent laryngeal nerve during thyroidectomy
    F Procacciante
    Department of VII Patologia Chirurgica, Policlinico Umberto I, Universita degli Studi di Roma La Sapienza, Rome, Italy
    World J Surg 24:571-3. 2000
    The major complication of thyroid surgery, occurring in 1% to 6% of cases, is injury to the recurrent laryngeal nerve (RLN). A simple method to identify the RLN during thyroid surgery is described by the authors...
  64. ncbi Recurrent laryngeal nerve injury following uncomplicated carotid angioplasty and stenting
    Geetha Jeyabalan
    Division of Vascular Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Endovasc Ther 16:345-8. 2009
    ..To describe a unique instance of cranial nerve injury related to uncomplicated carotid artery stenting (CAS)...
  65. ncbi A new anchor electrode design for continuous neuromonitoring of the recurrent laryngeal nerve by vagal nerve stimulations
    Rick Schneider
    Department of Surgery, University Hospital Leipzig, Leipzig, Germany
    Langenbecks Arch Surg 394:903-10. 2009
    Intraoperative neuromonitoring has the limitation that the recurrent laryngeal nerve (RLN) is still at risk for damage between two stimulations with a handheld bipolar stimulation electrode...
  66. ncbi An applied anatomical study on the recurrent laryngeal nerve and inferior thyroid artery
    Wen Jing Tang
    National Class Preclinical Medicine Experimental Teaching Demonstration Center, Chongqing Medical University, Chongqing 400016, China
    Surg Radiol Anat 34:325-32. 2012
    ..The aim of this study was to provide some important information about the morphology and topography of the recurrent laryngeal nerve (RLN) and inferior thyroid artery (ITA), which significantly helps localize and protect the RLN in neck ..
  67. ncbi Motor and sensory branching of the recurrent laryngeal nerve in thyroid surgery
    Emad Kandil
    Department of Surgery, Tulane University, School of Medicine, New Orleans, LA 70112, USA
    Surgery 150:1222-7. 2011
    Recognition of extralaryngeal bifurcation of the recurrent laryngeal nerve (RLN) is crucial, because inadvertent intraoperative division may lead to significant morbidity...
  68. ncbi Cricotracheal separation: a review and a case with bilateral recovery of recurrent laryngeal nerve function
    D J McCrystal
    Department of ENT Surgery, Ipswich Hospital, Queensland, Australia
    J Laryngol Otol 120:497-501. 2006
    ..Computerized tomography (CT) plays a role in diagnosis but cannot necessarily be relied upon. Bilateral recurrent laryngeal nerve (RLN) palsies are usually associated with this type of injury...
  69. ncbi Robot-assisted thoracoscopic lymphadenectomy along the left recurrent laryngeal nerve for esophageal squamous cell carcinoma in the prone position: technical report and short-term outcomes
    Koichi Suda
    Division of Upper GI, Department of Surgery, Fujita Health University, 1 98 Dengakugakubo, Kutsukake, Toyoake, 470 1192, Aichi, Japan
    World J Surg 36:1608-16. 2012
    Meticulous mediastinal lymphadenectomy frequently induces recurrent laryngeal nerve palsy (RLNP). Surgical robots with impressive dexterity and precise dissection skills have been developed to help surgeons perform operations...
  70. ncbi A case of Hodgkin's disease presenting with recurrent laryngeal nerve palsy and tracheoesophageal fistula
    A Munshi
    Department of Radiotherapy, Institute Rotary Cancer Hospital IRCH, All India Institute of Medical Sciences AIIMS Ansari Nagar, New Delhi, India
    Med J Malaysia 61:97-9. 2006
    ..The patient was treated with systemic chemotherapy and involved field radiotherapy. On follow up 1 year after the completion of treatment, he was clinically and radiologically disease free...
  71. ncbi Evaluating the safety of the Harmonic Scalpel around the recurrent laryngeal nerve
    Hang Jiang
    Minimally Invasive Surgical Centre, Changzheng Hospital, Second Military Medical University, Shanghai, China
    ANZ J Surg 80:822-6. 2010
    The Harmonic Scalpel (HS) is widely used in thyroidectomy. Determining the safety margin of using the HS near the recurrent laryngeal nerve (RLN) is helpful in preventing the injury to this nerve during thyroidectomy.
  72. ncbi Recurrent laryngeal nerve monitoring during thyroidectomy and related cervical procedures in the pediatric population
    W Matthew White
    Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, and Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Arch Otolaryngol Head Neck Surg 135:88-94. 2009
    To gather data on, and assess the applicability of, intraoperative recurrent laryngeal nerve (RLN) monitoring during thyroidectomy and related cervical procedures in children and adolescents...
  73. ncbi Intraoperative neurophysiology testing of the recurrent laryngeal nerve: plaudits and pitfalls
    Samuel K Snyder
    Department of Surgery, Scott and White Memorial Hospital and Clinic, Temple, TX, USA
    Surgery 138:1183-91; discussion 1191-2. 2005
    ..Whether this device enhances or hinders the identification and preservation of the recurrent laryngeal nerve (RLN) is unclear.
  74. ncbi The recurrent laryngeal nerve in thyroid surgery
    J P O'Neill
    Department of Otolaryngology, Mid Western Regional Hospital, Dooradoyle, Limerick
    Surgeon 6:373-7. 2008
    The recurrent laryngeal nerve (RLN) is an essential nerve for phonation and psychosocial interaction. Throughout the annals oflaryngological history, vocal cord paralysis has been a well recognised disorder...
  75. ncbi Recurrent laryngeal nerve injury with anterior cervical spine surgery risk with laterality of surgical approach
    W J Beutler
    SUNY Upstate Medical University, Department of Orthopedic Surgery, Syracuse, New York 13202, USA
    Spine (Phila Pa 1976) 26:1337-42. 2001
    ..OBJECTIVES: The primary purpose of the study is to determine whether there is in fact a greater risk of recurrent laryngeal nerve (RLN) injury with approach on the right or left side...
  76. ncbi The use of readily available equipment in a simple method for intraoperative monitoring of recurrent laryngeal nerve function during thyroid surgery: initial experience with more than 300 cases
    Holger K Eltzschig
    Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    Arch Surg 137:452-6; discussion 456-7. 2002
    An inexpensive and widely applicable technique to monitor recurrent laryngeal nerve (RLN) function during thyroid surgery can be safely implemented.
  77. ncbi Ansa-RLN reinnervation for unilateral vocal fold paralysis in adolescents and young adults
    Marshall E Smith
    Division of Otolaryngology, Head and Neck Surgery, Primary Children s Medical Center, University of Utah School of Medicine, The University of Utah, 3C 120 SOM, 50N Medical Dr, Salt Lake City, UT 84132, United States
    Int J Pediatr Otorhinolaryngol 72:1311-6. 2008
    ..To assess the outcomes of management of unilateral vocal fold paralysis by ansa-RLN reinnervation in a series of patients ages 12-21...
  78. ncbi Recurrent laryngeal nerve: a plexus rather than a nerve?
    Claudio R Cernea
    Department of Head and Neck Surgery, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Arch Otolaryngol Head Neck Surg 135:1098-102. 2009
    To analyze the frequency of extralaryngeal branching (ELB) of the recurrent laryngeal nerve (RLN) in a consecutive series of patients undergoing thyroidectomy by the same group of surgeons during an extended period and to compare our ..
  79. ncbi Functional modulation of satellite cells in long-term denervated human laryngeal muscle
    Chen Donghui
    Department of Otorhinolaryngology Head and Neck Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China
    Laryngoscope 120:353-8. 2010
    ..To evaluate the effects of long-term denervation on satellite cells (SCs) as myogenic stem cells in human posterior cricoarytenoid (PCA) muscle...
  80. ncbi Pulmonary mucormycosis presenting with recurrent laryngeal nerve palsy
    V Suresh
    Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India 160012
    J Assoc Physicians India 51:912-3. 2003
    ..We report an instance of polypoid endobronchial mucormycosis and vocal cord paralysis in a patient with type I diabetes and diabetic ketoacidosis...
  81. ncbi New operative surgical concept of two fascial layers enveloping the recurrent laryngeal nerve
    Jonathan W Serpell
    Monash University Endocrine Surgery Unit, The Alfred Hospital, Commercial Road, Melbourne, Vic, Australia
    Ann Surg Oncol 17:1628-36. 2010
    Avoiding recurrent laryngeal nerve (RLN) injury is aided by a precise anatomical understanding of the RLN before entry into the larynx where it is at greatest risk.
  82. ncbi Effect of recurrent laryngeal nerve section on the laryngeal muscles of adult rabbits
    Michael J Shinners
    Department of Otolaryngology, University of Minnesota, Rm 374 Lions Research Building, 2001 6th Street SE, Minneapolis, MN 55455, USA
    Otolaryngol Head Neck Surg 134:413-8. 2006
    To examine the effect of recurrent laryngeal nerve section on myonuclear addition and myofiber remodeling in adult rabbit laryngeal muscles.
  83. ncbi Clinical review: Current concepts in the management of unilateral recurrent laryngeal nerve paralysis after thyroid surgery
    Dana M Hartl
    Department of Otolaryngology and Head and Neck Surgery, Institut Gustave Roussy, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    J Clin Endocrinol Metab 90:3084-8. 2005
    This study was designed to provide an update on the pathophysiological concepts and patient management in a common complication of thyroid surgery, unilateral recurrent laryngeal nerve paralysis (URLNP).
  84. ncbi [The lobe of Zuckerkandl: an important sign of recurrent laryngeal nerve]
    Mario Costanzo
    Dipartimento di Scienze Chirurgiche, Trapianti d Organo e Tecnologie avanzate, P O Garibaldi, Cattedra e Servizio di Endocrinochirurgia, Universita di Catania
    Ann Ital Chir 76:337-40; discussion 340-1. 2005
    ..The identification of Zuckerkandl's tuberculum could reduce the lesions to the recurrent laryngeal nerve, for constant relationship between the recurrent laryngeal nerve and tuberculum.
  85. ncbi Quantitative estimation of the recurrent laryngeal nerve irritation by employing spontaneous intraoperative electromyographic monitoring during anterior cervical discectomy and fusion
    Vasilios G Dimopoulos
    Department of Neurosurgery, Medical Center of Central Georgia, School of Medicine, Mercer University, Macon, GA, USA
    J Spinal Disord Tech 22:1-7. 2009
    ..Prospective, clinical study...
  86. ncbi Ansa cervicalis-to-recurrent laryngeal nerve anastomosis for unilateral vocal fold paralysis: experience of a single institution
    Robert R Lorenz
    Head and Neck Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Ann Otol Rhinol Laryngol 117:40-5. 2008
    One treatment option for unilateral vocal fold paralysis (UVFP) is ansa cervicalis-to-recurrent laryngeal nerve (ansa-RLN) anastomosis to provide reinnervation to the affected vocal fold...
  87. ncbi Immediate recurrent laryngeal nerve reconstruction and vocal outcome
    Eiji Yumoto
    Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kumamoto University, Kumamoto, Japan
    Laryngoscope 116:1657-61. 2006
    The objective of this prospective study was to assess the long-term effects of immediate reconstruction of the recurrent laryngeal nerve (RLN) during thyroid cancer extirpation on postoperative phonatory function.
  88. ncbi Non-recurrent laryngeal nerve related to thyroid surgery: report of three cases
    C Page
    Department of ENT and Head and Neck Surgery, University Hospital of Amiens, Amiens, France
    J Laryngol Otol 122:757-61. 2008
    We aimed to highlight a rare anatomical variation involving the recurrent laryngeal nerve, and to emphasise its implications for thyroid surgery.
  89. ncbi Results of ansa to recurrent laryngeal nerve reinnervation
    Walter T Lee
    Department of Otolaryngology, Head and Neck Surgery, Cleveland Clinic, Cleveland, OH 44195, USA
    Otolaryngol Head Neck Surg 136:450-4. 2007
    We sought to describe the results of ansa cervicalis to recurrent laryngeal nerve (ansa-RLN) reinnervation for unilateral vocal fold paralysis.
  90. ncbi Neurorrhaphy of the recurrent laryngeal nerve
    Fong Fu Chou
    Department of Surgery, Chang Gung Memorial Hospital at Kaohsiung, Chang Gung University, Kaohsiung Hsien, Taiwan, ROC
    J Am Coll Surg 197:52-7. 2003
    It has been controversial to anastomose the severed recurrent laryngeal nerve after transection because when severed recurrent nerves are directly anastomosed, the vocal cords do not regain normal movements and are fixed in the median...
  91. ncbi Unilateral recurrent laryngeal nerve neuropraxia following placement of a ProSeal laryngeal mask airway in a patient with CREST syndrome
    Y Kawauchi
    Department of Anesthesiology and Critical Care Medicine, Tokyo Medical and Dental University, Tokyo, Japan
    Acta Anaesthesiol Scand 49:576-8. 2005
    We report a severe unilateral recurrent laryngeal nerve neuropraxia following use of the ProSeal laryngeal mask airway (PLMA) in a 71-year-old female patient with CREST syndrome...
  92. ncbi Intrinsic muscles and distribution of the recurrent laryngeal nerve in the pig larynx
    Melanie J Knight
    Division of Surgery of the Department of Anatomy and Clinical Medicine, University of Bristol, Bristol, UK
    Eur Arch Otorhinolaryngol 262:281-5. 2005
    ..We aimed to define the macroscopic anatomy of the intrinsic muscles and the course of the recurrent laryngeal nerve (RLN) in the pig larynx. Twelve large white pig larynges were used...
  93. ncbi On the incidence, cause, and prevention of recurrent laryngeal nerve palsies during anterior cervical spine surgery
    R I Apfelbaum
    Department of Neurosurgery, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Spine (Phila Pa 1976) 25:2906-12. 2000
    ..A retrospective review of contemporaneously acquired clinical data supplemented by experimental cadaver dissection...
  94. ncbi The inferior non recurrent laryngeal nerve: a major surgical risk during thyroidectomy
    T Defechereux
    Department of Transplant and Endocrine Surgery, CHU du Sart Tilman, University of Liege, Belgium
    Acta Chir Belg 100:62-7. 2000
    ..and 1997 for at least right thyroid lobe excision or parathyroid glands exploration, 20 cases of non recurrent laryngeal nerve were identified (0.79%)...
  95. ncbi Relative direction and position of recurrent laryngeal nerve for anatomical configuration
    Mi Sun Lee
    Catholic Institute for Applied Anatomy, Department of Anatomy, College of Medicine, The Catholic University of Korea, 505 Banpo Dong, Seocho Gu, Seoul 137 701, Republic of Korea
    Surg Radiol Anat 31:649-55. 2009
    The present study aims to describe the course of the recurrent laryngeal nerve (RLN) using the tracheoesophageal groove (TEG) at the cricothyroid joint as a base line, and the configuration of RLN and inferior thyroid artery (ITA) for ..
  96. ncbi Thyroid fine needle cytology complicated by recurrent laryngeal nerve palsy and unnecessary radical surgery
    S J Hulin
    Department of General Surgery, North Hants Hospital, Basingstoke, UK
    J Laryngol Otol 120:970-1. 2006
    ..We present the first report of recurrent laryngeal nerve palsy arising as a complication of thyroid nodule FNAC...
  97. ncbi An unusual course of the left recurrent laryngeal nerve
    Amir A Khaki
    Department of Neurosurgery and Anatomy, Tabriz University of Medical Sciences, Tabriz, Iran
    Clin Anat 20:344-6. 2007
    Variation in the course of the left recurrent laryngeal nerve is seemingly very rare...
  98. ncbi Intraoperative monitoring of the recurrent laryngeal nerve in 151 consecutive patients undergoing thyroid surgery
    T M Hemmerling
    Department of Anesthesiology, University Erlangen Nuremberg, Erlangen, Germany
    Anesth Analg 93:396-9 , 3rd contents page. 2001
    We present a technique of intraoperative monitoring of the recurrent laryngeal nerve using a surface electrode attached to a routine endotracheal tube...
  99. pmc Neuromonitoring in thyroid surgery: prospective evaluation of intraoperative electrophysiological responses for the prediction of recurrent laryngeal nerve injury
    Michael Hermann
    Department of Surgery, Kaiserin Elisabeth Spital, University of Vienna, Vienna, Austria
    Ann Surg 240:9-17. 2004
    ..We evaluated the ability of neuromonitoring to predict postoperative outcome in patients undergoing thyroid surgery for different indications...
  100. ncbi Recurrent laryngeal nerve palsy during anterior cervical spine surgery: a prospective study
    Axel Jung
    Departments of Neurosurgery and Ear, Nose, and Throat Surgery, Rheinische Friedrich Wilhelms Universitat Bonn, Germany
    J Neurosurg Spine 2:123-7. 2005
    b>Recurrent laryngeal nerve (RLN) palsy is a well-known complication of cervical spine surgery. Nearly all previous studies were performed without laryngoscopy in asymptomatic patients...
  101. ncbi Lateral mobilization of the recurrent laryngeal nerve to facilitate tracheal surgery in patients with thyroid cancer invading the trachea near Berry's ligament
    Akira Miyauchi
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    World J Surg 31:2081-4. 2007
    Thyroid cancer often invades the trachea and the recurrent laryngeal nerve (RLN) at or near Berry's ligament, which fixes the thyroid gland to the trachea...

Research Grants36

  1. Neurotrophin-Secreting Muscle Stem Cell Therapy for Laryngeal Paralysis
    Stacey L Halum; Fiscal Year: 2013
    ..Recent studies suggest that persistent vocal fold immobility after recurrent laryngeal nerve (RLN) injury is not due to lack of reinnervation, but due to aberrant, spontaneous reinnervation which ..
  2. Manipulating Macrophage Phenotype in Laryngeal Nerve Repair
    Jonathan Cheetham; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Vocal fold paralysis occurs when the recurrent laryngeal nerve (RLN) is injured, most commonly during surgery of the neck or thorax...
  3. Recurrent laryngeal nerve connective tissues as a factor in vocal fold paralysis
    Julie M Barkmeier-Kraemer; Fiscal Year: 2013
    ....
  4. Molecular Imaging of Retrograde Nerve Transport
    DAWID NONE SCHELLINGERHOUT; Fiscal Year: 2013
    ..Preventing loss of voice after neck surgery due to recurrent laryngeal nerve damage. Correctly diagnosing pinched nerves due to herniated disks in the spine...
  5. Neuromuscular control of the larynx
    DINESH KHATRI CHHETRI; Fiscal Year: 2013
    ..For conditions related to unilateral laryngeal paralysis and paresis of the recurrent laryngeal nerve (RLN), the same measurements will be repeated following variations of common surgical interventions for ..
  6. SELECTIVE ADDUCTOR RECOVERY AFTER LARYNGEAL NERVE INJURY
    Randal C Paniello; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Vocal fold paralysis occurs when the recurrent laryngeal nerve (RLN) is injured, frequently during surgery in the neck or chest...
  7. Adjustable balloon implant for medialization thyroplasty
    Matthew R Hoffman; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Vocal fold paralysis (VFP) is a disorder caused by damage to the recurrent laryngeal nerve. VFP impairs breathing, swallowing, and vocal function...
  8. Dysphagia and Recovery After Vagal or Laryngeal Nerve Injury
    Rebecca Z German; Fiscal Year: 2013
    ..of the impact of three independent, unilateral nerve injuries, superior laryngeal nerve (SA1), recurrent laryngeal nerve (SA2) and proximal vagus (SA3), on swallowing in an infant pig model...
  9. CRICOTHYROID REFLEX/RECURRENT LARYNGEAL NERVE PARALYSIS
    Gayle Woodson; Fiscal Year: 1992
    The proposed research will test the hypothesis that airway obstruction in bilateral recurrent laryngeal nerve paralysis is due to reflex stimulation of the cricothyroid muscle, and that suppression of this reflex would significantly ..
  10. Dynamic Vocal Fold Abduction for Bilateral Paralysis
    Michael Broniatowski; Fiscal Year: 2006
    ..It can follow as a complication of thyroid surgery, other trauma to the recurrent laryngeal nerve in the neck, base of skull or chest, by motor vehicle or other accidents, compression by lung or thyroid ..
  11. ANESTHESIA RESEARCH CENTER
    William Hamilton; Fiscal Year: 1980
    ..Spectral analysis of the phrenic and recurrent laryngeal nerve in the cat. MF Roizen: The effect of anesthetics on adrenergic activity...
  12. Medialization VS. Reinnervation For Vocal Cord Paralysis
    Jay Piccirillo; Fiscal Year: 2004
    Unilateral vocal fold paralysis (UVFP) is caused by injury to the recurrent laryngeal nerve. Patients with UVFP may have significant impairment of vocal cord function, including a breathy paralytic dysphonia...
  13. IMPLANTABLE STIMULATOR FOR PREVENTING ASPIRATION
    DUSTIN TYLER; Fiscal Year: 1999
    ..Recently, however, several animal studies have shown that electrical stimulation of the recurrent laryngeal nerve (RLN) can cause strong vocal cord adduction (VCA) and closure of the airway...
  14. LARYNGEAL REINNERVATION--CHARACTERIZATION OF SYNKINESIS
    Randal Paniello; Fiscal Year: 2000
    ..Synkinesis occurs when a severed recurrent laryngeal nerve (RLN) is repaired; the adductor and abductor fibers, which are intermixed within the common nerve trunk, ..
  15. Human Laryngeal Pacing for Aspiration
    Michael Broniatowski; Fiscal Year: 2005
    ..receive a stimulator implanted on the chest wall, linked to an electrode passed around the ipsilateral recurrent laryngeal nerve. Aspiration will be prevented by voluntary triggering glottic closure from a switch on an external ..
  16. NEURAL MECHANISMS IMPLICATED IN SUDDEN INFANT DEATH
    GREGORY LUCIER; Fiscal Year: 1980
    ..mechanisms regulating the activity of the laryngeal motoneurones recorded in nucleus ambiguous and the recurrent laryngeal nerve in the infant animal will also be studied for comparison with those presently under study in the adult.
  17. Electrode Array Reanimation of the Paralyzed Larynx
    Marshall Smith; Fiscal Year: 2006
    ..The hypothesis driving this project is that an implanted electrode array in the peripheral recurrent laryngeal nerve (RLN) can selectively stimulate laryngeal adductor muscles and abductor muscles...
  18. PHONATION AND PHONATORY CONTROL IN VOCAL TREMORS
    Marshall Smith; Fiscal Year: 2002
    ..The experimental phase consists of studies of neuromuscular and respiratory input to the larynx. This information about vocal tremor will be applied to model simulations with the use of physiological signals as input model parameters. ..
  19. DEVELOPING CIRCADIAN RHYTHMICITY
    Scott Rivkees; Fiscal Year: 2002
    ..These studies may also lead to the development of new care practices in Neonatal Intensive Care Units and extend the field of developmental chronobiology to the bedside. ..
  20. Adenosinergic Mechanisms of Intrauterine Growth Retardation
    Scott A Rivkees; Fiscal Year: 2010
    ..The goals of this proposal are to identify the mechanisms by which adenosine acts to protect the embryo in utero and how altered embryonic adenosine action leads to long-term adverse effects in adulthood. ..
  21. Radioactive Iodide Therapy of Pediatric Graves' Disease
    Scott A Rivkees; Fiscal Year: 2010
    ....
  22. The Role of Adenosine in Hypoglycemic Brain Injury
    Scott Rivkees; Fiscal Year: 2003
    ..We anticipate that these studies will yield new insights into the mechanisms of hypoglycemic brain injury and may lead to the development of practical strategies for reducing hypoglycemic brain injury. ..
  23. A1-ADENOSINE RECEPTOR ACTION IN HIPPOCAMPUS
    Scott Rivkees; Fiscal Year: 2003
    ..We anticipate these studies will lead to new insights into the mechanisms of A1AR action. We also anticipate that these studies will identify A1ARs as an important regulator of axon growth. ..
  24. CB1 Receptor Action on the Developing Hippocampus
    Scott Rivkees; Fiscal Year: 2005
    ..We anticipate that these studies will result in new insights into the potential effects of cannabinoid action on the developing brain. ..
  25. Vaccine therapy of congenital adrenal Hyperplasia
    Scott Rivkees; Fiscal Year: 2003
    ..We also anticipate being able to extend this novel approach to the treatment of other receptor-mediated endocrine disorders, such as hyperthyroidism. ..
  26. A-1 Adenosine Receptor Action in Developing Heart
    Scott Rivkees; Fiscal Year: 2005
    ..We anticipate that these studies will identify Rho and ROCK as critical signaling molecules in heart development and reveal that cardiac GTPase activity transduces the effects of adenosine. ..
  27. Anti-Adenosine Therapy of Neonatal Brain Injury
    Scott Rivkees; Fiscal Year: 2007
    ..It is anticipated that these studies will lead to novel and practical strategies for directly preventing brain injury. [unreadable] [unreadable]..
  28. Reflexes and Supraesophageal Consequences of Reflux Disease
    Brendan J Canning; Fiscal Year: 2010
    ..This research may also help identify novel therapeutic strategies for treating both GERD and chronic cough. ..
  29. AUTONOMIC REGULATION OF AIRWAY SMOOTH MUSCLE TONE
    BRENDAN CANNING; Fiscal Year: 2001
    ..It is anticipated that this information will improve our understanding of the role of the autonomic innervation of the healthy and diseased lung. ..
  30. KININS AS MEDIATORS OF HUMAN REACTIONS
    BRENDAN CANNING; Fiscal Year: 2003
    ..These rigorous studies will not only clarify the role of BK in airway diseases, but will also have broader relevance by providing new and important insights into how neural function is altered in asthma and rhinitis. ..
  31. Extracellular matrix and protease markers of malignant thyroid neoplasm
    Electron Kebebew; Fiscal Year: 2007
    ..We will use these results to design a multicenter clinical trial evaluating the diagnostic and prognostic value of ECM1 and TMPRSS4 expression in patients with thyroid neoplasm. [unreadable] [unreadable] [unreadable]..
  32. CONTROL-RESPIRATORY MODULATION OF SYMPATHETIC ACTIVITY
    Thomas Dick; Fiscal Year: 2003
    ..These proposed studies examine the mechanism of up-regulation of sympathetic nerve activity that is associated with sleep apnea. ..
  33. Cardiorespiratory Afferent Control in Heart Failure
    Thomas Dick; Fiscal Year: 2008
    ..These studies will demonstrate the role of pontine conditioning of afferent input in determining the effect pulmonary, baro-and chemo-sensory information on sympatho-respiratory rhythm in health and in HF. ..
  34. Limbic & Motor System Interaction in Laryngeal Function
    Douglas Van Daele; Fiscal Year: 2008
    ..It will promote a better understanding of how speech is acquired and generated at the cortical level, of voice disorders such as spasmodic dysphonia, of the focal dystonias, and of speech recovery after brain injury. ..
  35. Computer-Based Tools for Medialization Laryngoplasty
    Steven Bielamowicz; Fiscal Year: 2008
    ..abstract_text> ..