Genomes and Genes
Summary: Area of the temporal lobe concerned with hearing.
Publications351 found, 100 shown here
- Increased auditory cortical representation in musiciansC Pantev
Biomagnetism Center, Institute of Experimental Audiology, University of Munster, Germany
Nature 392:811-4. 1998....
- Sensitivity of newborn auditory cortex to the temporal structure of soundsSilke Telkemeyer
Berlin NeuroImaging Center, Charite University Medicine, 10117 Berlin, Germany
J Neurosci 29:14726-33. 2009..That is, the newborn auditory cortex is sensitive to the temporal structure of the auditory input and shows an emerging tendency for functional ..
- Correlating stimulus-specific adaptation of cortical neurons and local field potentials in the awake ratWolfger von der Behrens
Institute for Cell Biology and Neuroscience, Department of Biological Sciences, Goethe University, Frankfurt am Main, Germany
J Neurosci 29:13837-49. 2009..Stimulus-specific adaptation (SSA) of single neurons in the auditory cortex has been proposed to be the cellular substrate of MMN (Nelken and Ulanovsky, 2007)...
- Spectral interactions, but no mismatch negativity, in auditory cortex of anesthetized ratRonit Lazar
Department of Neurobiology and Behavior, University of California, Irvine, 2205 McGaugh Hall, Irvine, CA 92697, USA
Hear Res 181:51-6. 2003We used an 'oddball' stimulation paradigm to evoke epidural, event-related potentials over auditory cortex in urethane/xylazine-anesthetized rats, in order to study the neural mechanisms underlying the mismatch negativity (MMN)...
- Processing of low-probability sounds by cortical neuronsNachum Ulanovsky
Department of Physiology, Hebrew University, Hadassah Medical School, Box 12272, Jerusalem 91120, Israel
Nat Neurosci 6:391-8. 2003..We report here that neurons in cat primary auditory cortex (A1) responded more strongly to a rarely presented sound than to the same sound when it was common...
- Reconstructing speech from human auditory cortexBrian N Pasley
Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, California, United States of America
PLoS Biol 10:e1001251. 2012..To address this question, we used intracranial recordings from nonprimary auditory cortex in the human superior temporal gyrus to determine what acoustic information in speech sounds can be ..
- Selective cortical representation of attended speaker in multi-talker speech perceptionNima Mesgarani
Departments of Neurological Surgery and Physiology, UCSF Center for Integrative Neuroscience, University of California, San Francisco, California 94143, USA
Nature 485:233-6. 2012..listening task with two simultaneous speakers, we demonstrate that population responses in non-primary human auditory cortex encode critical features of attended speech: speech spectrograms reconstructed based on cortical responses to ..
- Maps and streams in the auditory cortex: nonhuman primates illuminate human speech processingJosef P Rauschecker
Laboratory of Integrative Neuroscience and Cognition, Georgetown University Medical Center, Washington, DC, USA
Nat Neurosci 12:718-24. 2009..Chief among these are physiological and anatomical studies showing that primate auditory cortex, across species, shows patterns of hierarchical structure, topographic mapping and streams of functional ..
- The processing of temporal pitch and melody information in auditory cortexRoy D Patterson
Centre for the Neural Basis of Hearing, Physiology Department, University of Cambridge, Downing Street, Cambridge, United Kingdom
Neuron 36:767-76. 2002..The results support the view that there is hierarchy of pitch processing in which the center of activity moves anterolaterally away from primary auditory cortex as the processing of melodic sounds proceeds.
- A disinhibitory microcircuit for associative fear learning in the auditory cortexJohannes J Letzkus
Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH 4058 Basel, Switzerland
Nature 480:331-5. 2011..of associative fear memories depends on the recruitment of a disinhibitory microcircuit in the mouse auditory cortex. Fear-conditioning-associated disinhibition in auditory cortex is driven by foot-shock-mediated cholinergic ..
- Tinnitus intensity dependent gamma oscillations of the contralateral auditory cortexElsa van der Loo
Brain Research centre Antwerp for Innovative and Interdisciplinary Neuromodulation BRAI 2 N, University Hospital Antwerp, Antwerp, Belgium
PLoS ONE 4:e7396. 2009..Tinnitus as a phantom phenomenon is related to hyperactivity and reorganization of the auditory cortex. Magnetoencephalography studies demonstrate a correlation between gamma band activity in the contralateral ..
- Synaptic mechanisms of direction selectivity in primary auditory cortexChang quan Ye
Institute of Neuroscience and State Key Laboratory of Neuroscience, Chinese Academy of Sciences, Shanghai 200031, China
J Neurosci 30:1861-8. 2010..Although many neurons in the auditory cortex are known to be selective for FM direction, the synaptic mechanisms underlying this selectivity are not well ..
- Rapid task-related plasticity of spectrotemporal receptive fields in primary auditory cortexJonathan Fritz
Center for Auditory and Acoustic Research, Institute for Systems Research, Electrical and Computer Engineering, University of Maryland, College Park, Maryland 20742, USA
Nat Neurosci 6:1216-23. 2003..We recorded neuronal responses in the primary auditory cortex of behaving ferrets that were trained to detect a target tone of any frequency...
- How the brain separates soundsRobert P Carlyon
MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 2EF, UK
Trends Cogn Sci 8:465-71. 2004..Listeners' sensitivity to streaming cues can be captured in the responses of neurons in the primary auditory cortex, and in EEG wave components with a short latency (< 200ms)...
- Stimulus-specific adaptation in the auditory thalamus of the anesthetized ratFlora M Antunes
Auditory Neurophysiology Unit, Laboratory for the Neurobiology of Hearing, Institute of Neuroscience of Castilla y Leon, University of Salamanca, Salamanca, Spain
PLoS ONE 5:e14071. 2010..Previous studies have demonstrated that neurons in the auditory cortex and inferior colliculus show SSA...
- A synaptic memory trace for cortical receptive field plasticityRobert C Froemke
Coleman Memorial Laboratory and W M Keck Foundation Center for Integrative Neuroscience, Department of Otolaryngology, University of California, San Francisco, California 94143, USA
Nature 450:425-9. 2007..Here we determine the dynamics of synaptic receptive field plasticity in the adult primary auditory cortex (also known as AI) using in vivo whole-cell recording...
- Spectral and temporal processing in human auditory cortexR J Zatorre
Montreal Neurological Institute, McGill University, 3801 University St, Montreal, QC H3A 2B4, Canada
Cereb Cortex 11:946-53. 2001We used positron emission tomography to examine the response of human auditory cortex to spectral and temporal variation...
- An oscillatory hierarchy controlling neuronal excitability and stimulus processing in the auditory cortexPeter Lakatos
Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Inst, Orangeburg, New York 10962, USA
J Neurophysiol 94:1904-11. 2005..current source density CSD] and multiunit activity (MUA), both spontaneous and stimulus-driven, in primary auditory cortex of awake macaque monkeys...
- The mechanisms of tinnitus: perspectives from human functional neuroimagingPeyman Adjamian
MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, United Kingdom
Hear Res 253:15-31. 2009....
- Multiple time scales of adaptation in auditory cortex neuronsNachum Ulanovsky
Department of Neurobiology, The Alexander Silberman Institute of Life Sciences, Hebrew University, Jerusalem 91904, Israel
J Neurosci 24:10440-53. 2004Neurons in primary auditory cortex (A1) of cats show strong stimulus-specific adaptation (SSA)...
- Visual activation of auditory cortex reflects maladaptive plasticity in cochlear implant usersPascale Sandmann
Department of Psychology, Neuropsychology Lab, Carl von Ossietzky University of Oldenburg, Germany
Brain 135:555-68. 2012Cross-modal reorganization in the auditory cortex has been reported in deaf individuals...
- Robustness of cortical topography across fields, laminae, anesthetic states, and neurophysiological signal typesWei Guo
Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
J Neurosci 32:9159-72. 2012..compared the strength of tonotopic organization at various depths within core and belt regions of the auditory cortex using electrophysiological measurements ranging from single units to delta-band local field potentials (LFP) ..
- Developmental sensory experience balances cortical excitation and inhibitionAnja L Dorrn
Department of Neuroscience, Max Delbruck Center for Molecular Medicine, and NeuroCure Neuroscience Research Center NWFZ, Berlin 13125, Germany
Nature 465:932-6. 2010Early in life, neural circuits are highly susceptible to outside influences. The organization of the primary auditory cortex (A1) in particular is governed by acoustic experience during the critical period, an epoch near the beginning of ..
- Auditory cortex is implicated in tinnitus distress: a voxel-based morphometry studyMartin Schecklmann
Department of Psychiatry and Psychotherapy, University of Regensburg, Universitätsstraße 84, 93053 Regensburg, Germany
Brain Struct Funct 218:1061-70. 2013..Our results support the notion that the role of the auditory cortex in tinnitus is not restricted to perceptual aspects...
- Laminar structure of spontaneous and sensory-evoked population activity in auditory cortexShuzo Sakata
Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
Neuron 64:404-18. 2009..cells, we compare the laminar structure of spontaneous and sensory-evoked population activity in rat auditory cortex. Spontaneous and evoked patterns both exhibited sparse, spatially localized activity in layer 2/3 pyramidal ..
- "Sparse" temporal sampling in auditory fMRID A Hall
MRC Institute of Hearing Research, Nottingham, UK
Hum Brain Mapp 7:213-23. 1999..g., attentive effort) induced by the intense background noise. We suggest that sparse imaging is advantageous in auditory experiments as it ensures that the obtained activation depends on the stimulus alone...
- Residual inhibition functions overlap tinnitus spectra and the region of auditory threshold shiftLarry E Roberts
Department of Psychology, Neuroscience, and Behaviour, McMaster University, 1280 Main Street West, Hamilton, ON, Canada, L8S 4K1
J Assoc Res Otolaryngol 9:417-35. 2008..Animals exposed to noise trauma show augmented synchronous neural activity in tonotopically reorganized primary auditory cortex consequent on hearing loss...
- Visual modulation of neurons in auditory cortexChristoph Kayser
Max Planck Institute for Biological Cybernetics, Spemannstrasse 38, 72076 Tubingen, Germany
Cereb Cortex 18:1560-74. 2008..These results demonstrate that visual stimuli can modulate the firing of neurons in auditory cortex in a manner that depends on stimulus efficacy and timing...
- Mechanisms and streams for processing of "what" and "where" in auditory cortexJ P Rauschecker
Georgetown Institute for Cognitive and Computational Sciences, Georgetown University Medical Center, Washington, DC 20007, USA
Proc Natl Acad Sci U S A 97:11800-6. 2000The functional specialization and hierarchical organization of multiple areas in rhesus monkey auditory cortex were examined with various types of complex sounds...
- Phase patterns of neuronal responses reliably discriminate speech in human auditory cortexHuan Luo
Neuroscience and Cognitive Science Program, Department of Biology, University of Maryland College Park, College Park, MD 20742, USA
Neuron 54:1001-10. 2007How natural speech is represented in the auditory cortex constitutes a major challenge for cognitive neuroscience...
- Mismatch negativity (MMN), the deviance-elicited auditory deflection, explainedPatrick J C May
Department of Biomedical Engineering and Computational Science, Helsinki University of Technology, Espoo, Finland
Psychophysiology 47:66-122. 2010..We propose that the MMN is, in essence, a latency- and amplitude-modulated expression of the auditory N1 response, generated by fresh-afferent activity of cortical neurons that are under nonuniform levels of adaptation...
- Human primary auditory cortex follows the shape of Heschl's gyrusSandra Da Costa
Neuropsychology and Neurorehabilitation Service, Lausanne University Hospital CHUV, Switzerland
J Neurosci 31:14067-75. 2011The primary auditory cortex (PAC) is central to human auditory abilities, yet its location in the brain remains unclear...
- "Who" is saying "what"? Brain-based decoding of human voice and speechElia Formisano
Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, University of Maastricht, 6200 MD Maastricht, Netherlands
Science 322:970-3. 2008..a person is listening to from the neural fingerprints that speech and voice signals elicit in the listener's auditory cortex. These cortical fingerprints are spatially distributed and insensitive to acoustic variations of the input so ..
- Preceding inhibition silences layer 6 neurons in auditory cortexYi Zhou
Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
Neuron 65:706-17. 2010..Here, cell-attached recordings in rat primary auditory cortex revealed that for the majority of L6 excitatory neurons, tonal stimuli did not drive spike responses, but ..
- Interactions between the superior temporal sulcus and auditory cortex mediate dynamic face/voice integration in rhesus monkeysAsif A Ghazanfar
Neuroscience Institute and Department of Psychology, Princeton University, Princeton, New Jersey 08540, USA
J Neurosci 28:4457-69. 2008..To test the hypothesis that multisensory responses in auditory cortex are influenced by visual inputs from the superior temporal sulcus (STS), an association area, we recorded ..
- Attention-driven auditory cortex short-term plasticity helps segregate relevant sounds from noiseJyrki Ahveninen
Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
Proc Natl Acad Sci U S A 108:4182-7. 2011..In conclusion, a simple gain model alone cannot explain auditory selective attention. In nonprimary auditory cortices, attention-driven short-term plasticity retunes neurons to segregate relevant sounds from noise...
- Dynamics of precise spike timing in primary auditory cortexMounya Elhilali
Institute for Systems Research, Department of Electrical and Computer Engineering, University of Maryland, College Park, Maryland 20742, USA
J Neurosci 24:1159-72. 2004Although single units in primary auditory cortex (A1) exhibit accurate timing in their phasic response to the onset of sound (precision of a few milliseconds), paradoxically, they are unable to sustain synchronized responses to repeated ..
- Spatial and temporal processing of single auditory cortical neurons and populations of neurons in the macaque monkeyGregg H Recanzone
Center for Neuroscience, Department of Neurobiology, Physiology and Behavior, University of California at Davis, One Shields Avenue, Davis, CA 95616, USA
Hear Res 271:115-22. 2011The auditory cortex is known to be a necessary neural structure for the perception of acoustic signals, particularly the spatial location and the temporal features of complex auditory stimuli...
- Projections to the inferior colliculus from layer VI cells of auditory cortexB R Schofield
Department of Anatomy and Neurobiology, Northeastern Ohio Universities College of Medicine, 4209 State Route 44, PO Box 95, Rootstown, OH 44272, USA
Neuroscience 159:246-58. 2009..a retrograde tracer into the inferior colliculus of guinea pigs labeled two bands of cells in the ipsilateral auditory cortex: a dense band of cells in layer V and a second band of cells in layer VI...
- Sensory-motor interaction in the primate auditory cortex during self-initiated vocalizationsSteven J Eliades
Laboratory of Auditory Neurophysiology, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
J Neurophysiol 89:2194-207. 2003Little is known about sensory-motor interaction in the auditory cortex of primates at the level of single neurons and its role in supporting vocal communication...
- Functional organization and population dynamics in the mouse primary auditory cortexGideon Rothschild
Department of Neurobiology, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel
Nat Neurosci 13:353-60. 2010..However, the functional organization and dynamics of local populations in the auditory cortex have remained largely unknown...
- Human primary auditory cortex: cytoarchitectonic subdivisions and mapping into a spatial reference systemP Morosan
Institute of Medicine, , Germany
Neuroimage 13:684-701. 2001The transverse temporal gyrus of Heschl contains the human auditory cortex. Several schematic maps of the cytoarchitectonic correlate of this functional entity are available, but they present partly conflicting data (number and position ..
- Precise inhibition is essential for microsecond interaural time difference codingAntje Brand
Max Planck Institute of Neurobiology, Am Klopferspitz 18a, 82152 Martinsried, Germany
Nature 417:543-7. 2002..A computer model, simulating the response of a coincidence-detector neuron with bilateral excitatory inputs and a temporally precise contralateral inhibitory input, supports this conclusion...
- Synaptic mechanisms of forward suppression in rat auditory cortexMichael Wehr
Cold Spring Harbor Laboratory, New York 11724, USA
Neuron 47:437-45. 2005In the auditory cortex, brief sounds elicit a powerful suppression of responsiveness that can persist for hundreds of milliseconds...
- Homeostatic plasticity drives tinnitus perception in an animal modelSungchil Yang
Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720, USA
Proc Natl Acad Sci U S A 108:14974-9. 2011..Enhancing sensory input through map reorganization may plausibly alleviate phantom sensation...
- Timbre-specific enhancement of auditory cortical representations in musiciansC Pantev
Biomagnetism Center, Institute for Experimental Audiology, , Germany
Neuroreport 12:169-74. 2001..Timbre specificity is predicted by a principle of use-dependent plasticity and imposes new requirements on nativistic accounts of brain attributes associated with musical skill...
- Activation of auditory cortex during silent lipreadingG A Calvert
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK
Science 276:593-6. 1997..magnetic resonance imaging it was found that these linguistic visual cues are sufficient to activate auditory cortex in normal hearing individuals in the absence of auditory speech sounds...
- Auditory cortex tracks both auditory and visual stimulus dynamics using low-frequency neuronal phase modulationHuan Luo
State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
PLoS Biol 8:e1000445. 2010....
- Auditory cortex on the human posterior superior temporal gyrusM A Howard
Department of Surgery Division of Neurosurgery, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
J Comp Neurol 416:79-92. 2000..These physiological findings are in accord with anatomic evidence in humans and in nonhuman primates that the superior temporal cortex contains multiple interconnected auditory areas...
- Motor-induced suppression of the auditory cortexSheye O Aliu
University of California San Francisco, USA
J Cogn Neurosci 21:791-802. 2009..In three MEG experiments, we characterize the properties of MIS by examining the M100 response from the auditory cortex to a simple tone triggered by a button press...
- Temporal predictive codes for spoken words in auditory cortexPierre Gagnepain
MRC Cognition and Brain Sciences Unit, Cambridge, UK
Curr Biol 22:615-21. 2012..This prediction error signal explains the efficiency of human word recognition and simulates neural responses in auditory regions...
- Tuning for spectro-temporal modulations as a mechanism for auditory discrimination of natural soundsSarah M N Woolley
Helen Wills Neuroscience Institute and Department of Psychology, University of California at Berkeley, Berkeley, California 94720, USA
Nat Neurosci 8:1371-9. 2005..Additionally, auditory neurons discriminate among zebra finch song segments better than among synthetic sound segments...
- Sparse representation of sounds in the unanesthetized auditory cortexTomás Hromádka
Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Cold Spring Harbor, New York, United States of America
PLoS Biol 6:e16. 2008How do neuronal populations in the auditory cortex represent acoustic stimuli? Although sound-evoked neural responses in the anesthetized auditory cortex are mainly transient, recent experiments in the unanesthetized preparation have ..
- Multiplexed and robust representations of sound features in auditory cortexKerry M M Walker
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK
J Neurosci 31:14565-76. 2011..In this study, we investigate whether neurons in both core and belt areas of ferret auditory cortex can robustly represent the pitch, formant frequencies, or azimuthal location of artificial vowel sounds while ..
- Auditory cortex activation is modulated by emotion: a functional near-infrared spectroscopy (fNIRS) studyM M Plichta
Central Institute of Mental Health, Mannheim, Germany
Neuroimage 55:1200-7. 2011..Pleasant and unpleasant sounds led to increased auditory cortex activation as compared to neutral sounds...
- The spectrotemporal filter mechanism of auditory selective attentionPeter Lakatos
Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Institute, Orangeburg, NY 10962, USA
Neuron 77:750-61. 2013..evidence that attention to auditory stimuli modulates neuronal responses at or before the level of primary auditory cortex (A1), the underlying physiological mechanisms are unknown...
- Cortical activity patterns predict robust speech discrimination ability in noiseJai A Shetake
The University of Texas at Dallas, School of Behavioral Brain Sciences, 800 West Campbell Road, GR41 Richardson, TX 75080 3021, USA
Eur J Neurosci 34:1823-38. 2011..We tested speech sound discrimination in rats and recorded primary auditory cortex (A1) responses to speech sounds in background noise of different intensities and spectral compositions...
- Physiological and anatomical evidence for multisensory interactions in auditory cortexJennifer K Bizley
Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford OX1 3PT, UK
Cereb Cortex 17:2172-89. 2007..recordings and estimates of mutual information that visual stimuli can influence the activity of units in the auditory cortex of anesthetized ferrets...
- Impaired mismatch negativity (MMN) generation in schizophrenia as a function of stimulus deviance, probability, and interstimulus/interdeviant intervalD C Javitt
Nathan Kline Institute for Psychiatric Research New York University School of Medicine, Orangeburg 10962, USA
Electroencephalogr Clin Neurophysiol 108:143-53. 1998..The pattern of deficit observed in schizophrenia differs from the pattern observed in other conditions associated with MMN dysfunction, including Alzheimer's disease, stroke, and alcohol intoxication...
- Learning-stage-dependent, field-specific, map plasticity in the rat auditory cortex during appetitive operant conditioningH Takahashi
Research Center for Advanced Science and Technology, The University of Tokyo, Komaba 4 6 1, Meguro ku, Tokyo 153 8904, Japan
Neuroscience 199:243-58. 2011..In the present study, microelectrode mapping characterized plasticity in the rat auditory cortex, including primary, anterior, and ventral/suprarhinal auditory fields (A1, AAF, and VAF/SRAF), at the early ..
- Non-sensory cortical and subcortical connections of the primary auditory cortex in Mongolian gerbils: bottom-up and top-down processing of neuronal information via field AIEike Budinger
Leibniz Institute for Neurobiology, Department of Auditory Learning and Speech, Brenneckestrasse 6, D 39118 Magdeburg, Germany
Brain Res 1220:2-32. 2008In the present study, we will provide further anatomical evidence that the primary auditory cortex (field AI) is not only involved in sensory processing of its own modality, but also in complex bottom-up and top-down processing of ..
- GABA shapes selectivity for the rate and direction of frequency-modulated sweeps in the auditory cortexKhaleel A Razak
Department 3166, Zoology and Physiology, University of Wyoming, 1000 E University Ave, Laramie, WY 82071, USA
J Neurophysiol 102:1366-78. 2009In the pallid bat auditory cortex and inferior colliculus (IC), the majority of neurons tuned in the echolocation range is selective for the direction and rate of frequency-modulated (FM) sweeps used in echolocation...
- Activity associated with stream segregation in human auditory cortex is similar for spatial and pitch cuesStefan Schadwinkel
Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, Heidelberg, Germany
Cereb Cortex 20:2863-73. 2010..and potential neural correlates for streaming based on spectral and pitch cues have been identified in the auditory cortex. Here, magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) were used to evaluate if ..
- Suppressed responses to self-triggered sounds in the human auditory cortexMika H Martikainen
Department of Clinical Neurophysiology, Helsinki University Central Hospital, FIN 00290 Helsinki, Finland
Cereb Cortex 15:299-302. 2005..Here we tested whether responses in the human auditory cortex would differ to self-triggered versus externally triggered tones...
- Effect of auditory cortex deactivation on stimulus-specific adaptation in the medial geniculate bodyFlora M Antunes
Auditory Neurophysiology Unit, Laboratory for the Neurobiology of Hearing, Institute of Neuroscience of Castilla y Leon, Calle Pintor Fernando Gallego, 1, Spain
J Neurosci 31:17306-16. 2011..In the auditory system, SSA has been identified in the midbrain, thalamus, and auditory cortex (AC)...
- Visual enhancement of the information representation in auditory cortexChristoph Kayser
Max Planck Institute for Biological Cybernetics, Spemannstrasse 38, 72076 Tubingen, Germany
Curr Biol 20:19-24. 2010..By recording in auditory cortex of alert monkeys watching naturalistic audiovisual stimuli, we quantified the effect of visual influences on ..
- Functional connectivity and cholinergic modulation in auditory cortexRaju Metherate
Department of Neurobiology and Behavior, Center for Hearing Research, University of California Irvine, CA 92697 4550, United States
Neurosci Biobehav Rev 35:2058-63. 2011Although it is known that primary auditory cortex (A1) contributes to the processing and perception of sound, its precise functions and the underlying mechanisms are not well understood...
- Contrast gain control in auditory cortexNeil C Rabinowitz
Department of Physiology, Anatomy, and Genetics, Sherrington Building, Parks Road, University of Oxford, Oxford OX13PT, UK
Neuron 70:1178-91. 2011..We show that neurons in ferret auditory cortex rescale their gain to partially compensate for the spectrotemporal contrast of recent stimulation...
- Tone-evoked excitatory and inhibitory synaptic conductances of primary auditory cortex neuronsAndrew Y Y Tan
Coleman Memorial Laboratory and W M Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco, CA 94143, USA
J Neurophysiol 92:630-43. 2004In primary auditory cortex (AI) neurons, tones typically evoke a brief depolarization, which can lead to spiking, followed by a long-lasting hyperpolarization...
- Morphology of Heschl's gyrus reflects enhanced activation in the auditory cortex of musiciansPeter Schneider
Department of Physics, University of Heidelberg, Philosophenweg 12, D 69120 Heidelberg, Germany
Nat Neurosci 5:688-94. 2002Using magnetoencephalography (MEG), we compared the processing of sinusoidal tones in the auditory cortex of 12 non-musicians, 12 professional musicians and 13 amateur musicians...
- Mirror-symmetric tonotopic maps in human primary auditory cortexElia Formisano
Department of Cognitive Neuroscience, Faculty of Psychology, Universiteit Maastricht, Postbus 616, 6200MD Maastricht, The Netherlands
Neuron 40:859-69. 2003Understanding the functional organization of the human primary auditory cortex (PAC) is an essential step in elucidating the neural mechanisms underlying the perception of sound, including speech and music...
- Changes in spontaneous firing rate and neural synchrony in cat primary auditory cortex after localized tone-induced hearing lossSatoshi Seki
Departments of Physiology and Biophysics, and Psychology, University of Calgary, 2500 University Drive N W, Calgary, AB, Canada T2N 1N4
Hear Res 180:28-38. 2003..The frequency representation in primary auditory cortex was mapped using an eight-electrode array. Single-unit spontaneous activity was recorded for 15 min...
- Topography and synaptic shaping of direction selectivity in primary auditory cortexLi I Zhang
Coleman Memorial Laboratory and W M Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco, California 94143, USA
Nature 424:201-5. 2003..FM direction-selective neurons are found in the primary auditory cortex (A1), but their topography and the mechanisms underlying their selectivity remain largely unknown...
- Repetition suppression and plasticity in the human brainMarta I Garrido
Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, UK
Neuroimage 48:269-79. 2009..It is remarkable that distinct changes in intrinsic and extrinsic connections could be quantified so reliably and non-invasively using EEG...
- Lateral sharpening of cortical frequency tuning by approximately balanced inhibitionGuangying K Wu
Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, 1501 San Pablo Street, Los Angeles, CA 90033, USA
Neuron 58:132-43. 2008..Here, in vivo whole-cell recordings from neurons in the rat primary auditory cortex revealed that the frequency tuning curve of inhibitory input was broader than that of excitatory input...
- Redefining the tonotopic core of rat auditory cortex: physiological evidence for a posterior fieldNeot N Doron
W M Keck Laboratories of Neurobiology, Center for Neural Science, New York University, New York, New York 10003, USA
J Comp Neurol 453:345-60. 2002..Finally, the physiological data suggest that core auditory cortex (temporal area TE1) is composed not only of AI as previously thought, but also of at least two other ..
- Neural activity in speech-sensitive auditory cortex during silenceM D Hunter
Sheffield Cognition and Neuroimaging Laboratory SCANLab, Academic Clinical Psychiatry, Division of Genomic Medicine, University of Sheffield, Sheffield S5 7JT, United Kingdom
Proc Natl Acad Sci U S A 103:189-94. 2006..heard in the absence of external stimuli implies the existence of endogenous neural activity within the auditory cortex responsible for their perception...
- Early auditory experience generates long-lasting memories that may subserve vocal learning in songbirdsMimi L Phan
Department of Psychology, Rutgers University, Piscataway, NJ 08854, USA
Proc Natl Acad Sci U S A 103:1088-93. 2006..Furthermore, the strength of this selectivity shows a striking correlation with the fidelity of vocal imitation, suggesting that this auditory memory may have served as the model for song learning...
- Listening to tailor-made notched music reduces tinnitus loudness and tinnitus-related auditory cortex activityHidehiko Okamoto
Institute for Biomagnetism and Biosignalanalysis, Westfalian Wilhelms University, Malmedyweg 15, Muenster, Germany
Proc Natl Acad Sci U S A 107:1207-10. 2010Maladaptive auditory cortex reorganization may contribute to the generation and maintenance of tinnitus...
- Auditory plasticity and hyperactivity following cochlear damageR J Salvi
Hearing Research Lab, University of Buffalo, 215 Parker Hall, Buffalo, NY 14214, USA
Hear Res 147:261-74. 2000..of IHC loss, the IC response shows only a modest amplitude reduction, and remarkably, the response of the auditory cortex is enhanced...
- Encoding of learned importance of sound by magnitude of representational area in primary auditory cortexRichard G Rutkowski
Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697 3800, USA
Proc Natl Acad Sci U S A 102:13664-9. 2005We hypothesized that learning-induced representational expansion in the primary auditory cortex (AI) directly encodes the degree of behavioral importance of a sound...
- Birdsong memory: a neural dissociation between song recognition and productionSharon M H Gobes
Behavioural Biology and Helmholtz Institute, Utrecht University, Padualaan 8, P O Box 80086, 3508 TB Utrecht, The Netherlands
Curr Biol 17:789-93. 2007..Thus, in both humans and songbirds, the cognitive systems of vocal production and auditory recognition memory are subserved by distinct brain regions...
- Cortical representation of natural complex sounds: effects of acoustic features and auditory object categoryAmber M Leaver
Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC 20057, USA
J Neurosci 30:7604-12. 2010..sounds are thought to be represented by neurons responding to increasing degrees of complexity throughout auditory cortex, with complete auditory "objects" encoded by neurons (or small networks of neurons) in anterior superior ..
- Binary spiking in auditory cortexMichael R Deweese
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
J Neurosci 23:7940-9. 2003..We have, therefore, assessed trial-to-trial variability in the auditory cortex of the rat. To ensure single-unit isolation, we used cell-attached recording...
- Cross-modal plasticity in specific auditory cortices underlies visual compensations in the deafStephen G Lomber
Centre for Brain and Mind, Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada
Nat Neurosci 13:1421-7. 2010..In the absence of acoustic input, it has been proposed that cross-modal reorganization of deaf auditory cortex may provide the neural substrate mediating compensatory visual function...
- Stimulus-specific adaptation and deviance detection in the rat auditory cortexNevo Taaseh
Department of Neurobiology, Silberman Institute of Life Sciences, Hebrew University, Jerusalem, Israel
PLoS ONE 6:e23369. 2011..We studied SSA in the auditory cortex of halothane-anesthetized rats, recording local field potentials and multi-unit activity...
- Relationship of imprecise corollary discharge in schizophrenia to auditory hallucinationsTheda H Heinks-Maldonado
Department of Neuropsychology, Albert Ludwigs Universitat, Freiburg, Germany
Arch Gen Psychiatry 64:286-96. 2007..Imprecision of the corollary discharge in schizophrenia may contribute to the misperception of inner experiences and thoughts as "voices" or auditory hallucinations...
- Prior expectation mediates neural adaptation to repeated sounds in the auditory cortex: an MEG studyAna Todorović
Donders Institute for Brain, Cognition, and Behaviour, Radboud University Nijmegen, 6500 HB Nijmegen, The Netherlands
J Neurosci 31:9118-23. 2011..We found robust repetition suppression in the auditory cortex for repeated tones...
- Balanced inhibition underlies tuning and sharpens spike timing in auditory cortexMichael Wehr
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA
Nature 426:442-6. 2003Neurons in the primary auditory cortex are tuned to the intensity and specific frequencies of sounds, but the synaptic mechanisms underlying this tuning remain uncertain...
- Sound categories are represented as distributed patterns in the human auditory cortexNoel Staeren
Faculty of Psychology and Neuroscience, Department of Cognitive Neuroscience, University of Maastricht, 6200 MD Maastricht, The Netherlands
Curr Biol 19:498-502. 2009....
- Fine-tuning of pre-balanced excitation and inhibition during auditory cortical developmentYujiao J Sun
Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
Nature 465:927-31. 2010..Here we apply in vivo whole-cell voltage-clamp recordings to the recipient layer 4 neurons in the rat primary auditory cortex (A1) to determine the developmental changes in the frequency-intensity tonal receptive fields (TRFs) of their ..
- Rapid synaptic depression explains nonlinear modulation of spectro-temporal tuning in primary auditory cortex by natural stimuliStephen V David
Institute for Systems Research, University of Maryland, College Park, Maryland 20742, USA
J Neurosci 29:3374-86. 2009In this study, we explored ways to account more accurately for responses of neurons in primary auditory cortex (A1) to natural sounds...
- Perceptual organization of tone sequences in the auditory cortex of awake macaquesChristophe Micheyl
Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
Neuron 48:139-48. 2005..formation measured in humans using alternating-tone sequences can be quantitatively accounted for based on single-unit responses recorded in the primary auditory cortex (A1) of awake rhesus monkeys listening to the same sound sequences.
- Perceptual learning directs auditory cortical map reorganization through top-down influencesDaniel B Polley
W M Keck Foundation Center for Integrative Neuroscience, Department of Otolaryngology, University of California, San Francisco, California 94143 0732, USA
J Neurosci 26:4970-82. 2006..We tested whether topographic map plasticity in the adult primary auditory cortex and a secondary auditory area, the suprarhinal auditory field, was controlled by the statistics of bottom-up ..
- Temporal and rate representations of time-varying signals in the auditory cortex of awake primatesT Lu
Laboratory of Auditory Neurophysiology, Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 424, Baltimore, Maryland 21205, USA
Nat Neurosci 4:1131-8. 2001..Here we show that there are two largely distinct populations of neurons in the auditory cortex of awake primates: one with stimulus-synchronized discharges that, with a temporal code, explicitly ..
- Altered low-γ sampling in auditory cortex accounts for the three main facets of dyslexiaKatia Lehongre
Inserm U960 École Normale Supérieure, 75005 Paris, France
Neuron 72:1080-90. 2011..bias for phonemic processing, reflected in less entrainment to ≈30 Hz acoustic modulations in left auditory cortex. This deficit correlates with measures of phonological processing and rapid naming...
- Neuronal representations of distance in human auditory cortexNorbert Kopco
Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School Massachusetts General Hospital, Charlestown, MA 02129, USA
Proc Natl Acad Sci U S A 109:11019-24. 2012....
- Altered cross-modal processing in the primary auditory cortex of congenitally deaf adults: a visual-somatosensory fMRI study with a double-flash illusionChristina M Karns
Department of Psychology and Institute of Neuroscience, University of Oregon, Eugene, Oregon 97403, USA
J Neurosci 32:9626-38. 2012..cross-modal neuroplasticity in anatomically defined subregions of Heschl's gyrus, the site of human primary auditory cortex, in congenitally deaf humans by measuring the fMRI signal change in response to spatially coregistered visual,..
- Evidence for opponent-channel coding of interaural time differences in human auditory cortexDavid A Magezi
MRC Institute of Hearing Research, University Park, Nottingham, NG7 2RD, UK
J Neurophysiol 104:1997-2007. 2010..The hemispheric distributions of the ITD change responses suggest that the majority of ITD-sensitive neurons in each hemisphere are tuned to ITDs from the contralateral hemifield...
- Neurons with stereotyped and rapid responses provide a reference frame for relative temporal coding in primate auditory cortexRomain Brasselet
Max Planck Institute for Biological Cybernetics, 72076 Tubingen, Germany
J Neurosci 32:2998-3008. 2012..Studying the encoding of naturalistic sounds in primate (Macaca mulatta) auditory cortex we here investigate potential intrinsic references for decoding temporally precise information...
- Cortical map plasticity improves learning but is not necessary for improved performanceAmanda Reed
School of Behavioral and Brain Sciences, GR41, The University of Texas at Dallas, Richardson, TX 75080 3021, USA
Neuron 70:121-31. 2011..in perceptual ability after pairing tones with stimulation of the cholinergic nucleus basalis to induce auditory cortex map plasticity outside of a behavioral context...
- CODING IN AUDITORY NEURONS: EFFECTS OF AMINO ACIDSDonald M Caspary; Fiscal Year: 2013..in GABA- and glycinergic inhibitory pharmacology and physiology in the dorsal cochlear nucleus and primary auditory cortex. Proposal studies will examine the nature of GABAA receptors (GABAARs) at the level of the medial geniculate ..
- Brain changes in tinnitusJosef P Rauschecker; Fiscal Year: 2010..touches on the face (which are normally processed in an adjacent area of somatosensory cortex), the areas of auditory cortex affected by hearing loss start responding to hearing-loss edge frequencies...
- CRCNS: Gamma Rhythms and Cell AssembliesNancy Kopell; Fiscal Year: 2013..We will use in vitro models of the primary auditory cortex, with gamma oscillations induced using the glutamatergic agonist kainate or the cholinergic agonist carbachol...
- Auditory Cortex Plasticity and TinnitusBrian Allman; Fiscal Year: 2012..intramodal cortical plasticity), and in the case of profound deafness caused by ototoxicity, neurons in the auditory cortex becoming responsive to somatosensory stimulation (i.e., crossmodal cortical plasticity)...
- Effectiveness of Therapy via Telemedicine following Cochlear ImplantsAnu Sharma; Fiscal Year: 2013..nerve, allowing auditory input to circumvent damaged hair cells in the cochlea, and hence to stimulate the auditory cortex. CI can facilitate normal speech/language development during the first 3...
- Synaptic basis of perceptual learning in primary auditory cortexROBERT CROOKS FROEMKE; Fiscal Year: 2013..This plasticity is essential for learning and memory, and is an important feature of the auditory cortex, especially for learning the significance of sensory signals such as speech, for the use of devices such as ..
- Cholinergic inputs to excitatory and inhibitory midbrain auditory circuitsJEFFREY GARRETT MELLOTT; Fiscal Year: 2013..Descending projections from auditory cortex to the inferior colliculus of the midbrain play a role in a wide range of auditory functions, including ..
- Cross-modal re-organization in children with cochlear implantsJulia Dee Campbell; Fiscal Year: 2013..Indeed, cases of visual-to-auditory cross-modal re-organization (visual cortical recruitment via auditory cortex) have been found via high-density electroencephalography (EEG) recordings in adults who received cochlear ..
- Anatomical analysis of cortical projections to the auditory midbrainKYLE TOKUICHI NAKAMOTO; Fiscal Year: 2012..The auditory cortex is the source of massive descending projections that are considered to play a role in a wide range of ..
- Electrophysiological mapping of corticocollicular projections involved with tonotHUBERT HYUNGIL LIM; Fiscal Year: 2013..electrophysiological techniques to map out the functional and anatomical projection patterns from the primary auditory cortex (A1) to the central nucleus of the inferior colliculus (ICC)...
- FUNCTIONAL ORGANIZATION OF PRIMARY AUDITORY CORTEXChristoph E Schreiner; Fiscal Year: 2013..We attempt to explore the normal function of the auditory cortex for processing complex signals and signals in different types of background noise in order to ascertain the ..
- Auditory Cortex: Synaptic organization and plasticityPaul B Manis; Fiscal Year: 2013..we will explore local circuit organization within and orthogonal to the tonotopic axes of the primary auditory cortex, the mechanisms regulating synaptic plasticity in those circuits, and the effects of hearing loss on circuit ..
- Integration of ascending and descending input to auditory cortexMatthew I Banks; Fiscal Year: 2013..Here, we propose to investigate the cellular and circuit mechanisms of this integrative process in auditory cortex and its modulation by general anesthetics...
- AUDITORY MEMORIES AND VOCAL LEARNINGFrederic E Theunissen; Fiscal Year: 2013..we have characterized responses in the avian auditory midbrain, thalamus and in the primary and secondary auditory cortex. We have shown that auditory neurons are specialized to represent natural sounds and that we can explain this ..
- The Impact of Frequency Compression on Cortical Evoked Potentials and PerceptionBenjamin J Kirby; Fiscal Year: 2013..been established that cortical auditory evoked potentials (CAEPs), objective recordings of activity in the auditory cortex, may serve as an alternative to parental report for fitting hearing aids...
- Cortical Responses to Cochlear Implant Stimulation LUKE AARON JOHNSON; Fiscal Year: 2012..Its hearing range is similar to that of humans and its auditory cortex shares similar organizations as humans, making it a valuable model to address issues in CI research ..
- The effects of aging and hearing loss on human auditory cortexDavid L Woods; Fiscal Year: 2013DESCRIPTION (provided by applicant): Human auditory cortex (HAC) is a complex area that contains multiple, functionally specialized auditory cortical fields (ACFs)...
- Epigenetics of neuronal plasticity in auditory cortex in a sensory memory modelKerry J Ressler; Fiscal Year: 2013..auditory learning and memory, behavioral and electrophysiological evidence point to a key role played by the auditory cortex, but the molecular mechanisms operating there to enable memory formation and maintenance are unknown...
- Parsing the schizophrenia-bipolar spectrum: an MEG based schizoaffective endophenMartin Reite; Fiscal Year: 2010..status of GABAergic interneuronal activity regulating firing patterns of layer 3 pyramidal cells in auditory cortex of Heschl's gyrus...
- Contributions of peripheral spatial resolution to speech perception in CI usersRachel A Scheperle; Fiscal Year: 2013..resolution (ECAP forward masking), we propose using two electrophysiological measures of processing at the auditory cortex: a measure of spatial resolution (discrimination between two electrodes) and a measure of spectral resolution ..
- Towards understanding cellular mechanisms of positive symptoms of schizophreniaStanislav S Zakharenko; Fiscal Year: 2013..of 22q11DS have substantial deficits in synaptic transmission and short-term plasticity at TC pathways to the auditory cortex. In this proposal, we will use single-cell electrophysiology, 2-photon imaging, 2-photon glutamate uncaging, ..
- Amygdalar modulation of processing in auditory cortexDIANA COOMES PETERSON; Fiscal Year: 2012..processes the emotional significance of sensory stimuli) influences the processing of auditory information in auditory cortex (AC). Individuals/animals pay more attention to significant versus insignificant stimuli...
- Somatosensory-to-auditory cross-modal plasticity in cochlear implanted childrenGARRETT JOSEPH CARDON; Fiscal Year: 2013..have demonstrated convincing evidence in both animals and humans that the visual system can recruit the auditory cortex in deafness...
- Rescue of cortical inhibitory synapses following developmental hearing lossDAN HARVEY SANES; Fiscal Year: 2013..related aims: Aim 1 will first determine whether the effect of developmental conductive hearing loss (CHL) on auditory cortex inhibitory synapse function persists into adulthood...
- Neural Correlates of Streaming of Complex SoundsShihab A Shamma; Fiscal Year: 2013..Neural responses to sound streams will be measured in different fields of the ferret auditory cortex (spanning both primary or "core" and secondary or "belt" areas) under different attentional conditions, ..
- Behavioral and physiological studies of sound localizationTom C T Yin; Fiscal Year: 2013..The other circuit involves projections from the inferior colliculus to the medial geniculate and primary auditory cortex. By inactivating the cortex or the midbrain, the relative roles of these two circuits in orienting behavior ..
- Information Processing in Auditory CortexXiaoqin Wang; Fiscal Year: 2013..both neural mechanisms for processing communication sounds and fundamental neural coding mechanisms in auditory cortex that subserve cortical representations of biologically relevant sounds...
- Pilot Clinical Trial of Deep Brain Stimulation for TinnitusPaul Larson; Fiscal Year: 2013..such as hearing aids, neurobehavioral sound extinction procedures, and magnetic or electrical stimulation of auditory cortex. Those tinnitus sufferers have little therapeutic recourse...
- Floating Light Activated Micro-Electrical Stimulators for Neural ProstheticsMesut Sahin; Fiscal Year: 2012..locomotion or micturition in spinal cord injury, microstimulation of the cochlear nucleus, midbrain, or auditory cortex to restore hearing, and stimulation of the visual cortex in the blind subjects...
- Functions of Associative Auditory Cortical PlasticityNorman M Weinberger; Fiscal Year: 2013..The rich and complex domain of auditory memory is enabled by the plasticity of the auditory cortex. For example, learning is accompanied by shifts of frequency tuning to emphasize sounds that become ..
- Activity-Dependent Influences on Auditory CircuitsDaniel B Polley; Fiscal Year: 2013..period regulation of binaural processing in the inferior colliculus, medial geniculate body and primary auditory cortex. Continuing studies will compare the effects of unilateral versus bilateral CHL on the functional ..
- Auditory Cortical Processing of Communication SoundsKAMAL K SEN; Fiscal Year: 2010b>Auditory cortex plays an important role in the processing of complex sounds e.g., vocal communication sounds and human speech...
- Songbird Neurogenomics InitiativeDavid F Clayton; Fiscal Year: 2010..how they compare to other regions including brain areas that correspond to parts of human brain (such as auditory cortex and cortical regions for the control of speech production)...
- Effects of language experience on early cortical and subcortical pitch encodingAnanthanarayan Krishnan; Fiscal Year: 2013..approach to evaluate pitch representations at the brainstem (frequency following response, FFR) and auditory cortex (cortical pitch response, CPR) concurrently...
- Neural mechanisms of speech learning in older adultsPATRICK C WONG; Fiscal Year: 2012..in the decline-compensation model of the aging brain, which postulates that decline in sensory abilities (auditory cortex) can be compensated by increased engagement of general cognitive cortical regions such as the prefrontal ..
- Gene Expression During Postnatal Development of the Central Auditory PathwayTroy A Hackett; Fiscal Year: 2013..in situ hybridization, and immunohistochemistry to: (1) identify genes that are differentially expressed in auditory cortex, medial geniculate, and inferior colliculus during postnatal development;and (2) localize the transcripts of ..
- Critical Periods of Recovery from Hearing Loss in the Developing Auditory CortexTodd Mowery; Fiscal Year: 2013..e., earplug removal) during development will influence cellular properties in auditory cortex. Both the onset of earplug insertion and the time of earplug removal will be varied as a function of ..
- Synaptic mechanisms of auditory memoryStanislav S Zakharenko; Fiscal Year: 2013..The auditory cortex (ACx) acquires and retains specific memory traces about the behavioral significance of selected sounds...
- Voltage-sensitive dye imaging setupDieter Jaeger; Fiscal Year: 2013..allow this work to progress towards a better understanding of spatial and temporal signal flow beyond primary auditory cortex. For both Dr Jaeger and Dr...
- Cross-modal changes in auditory cortex circuitry after visual deprivationEMILY ROSE PETRUS; Fiscal Year: 2013..Results from this work will directly impact our understanding of how spared sensory modalities become enhanced following the loss of one sense. ..
- Multisensory integration of faces and voices in the primate temporal lobeASIF GHAZANFAR; Fiscal Year: 2013..The focus of our work will be on what role the auditory cortex plays in integrating faces and voices, and how its role may different from that of the more traditional ..
- CRCNS: Optimality principles of auditory representationsKechen Zhang; Fiscal Year: 2013..we also obtain a plausible network explanation of how complex response properties in inferior colliculus and auditory cortex might arise from combining multiple sound localization cues at lower levels in the auditory pathway...
- Cortical correlates of age-related hearing deficitsGREGG HOWARD RECANZONE; Fiscal Year: 2013..is due in large part to the lack of an effective animal model that (1) shares many organizational features of auditory cortex with humans, (2) has a reasonably long life span such that age-related hearing deficits progress over the ..
- Neural Encoding and Connectivity in human speech perceptionBRIAN PASLEY; Fiscal Year: 2013..K99 phase, the first specific aim will investigate the neural representation of speech in higher order auditory cortex using a neural encoding model approach...
- The role of cortico-hippocampal interactions in encoding auditory memoriesDANIEL A BENDOR; Fiscal Year: 2012..hippocampus for recall;however, this memory eventually becomes hippocampus-independent and consolidated in auditory cortex. Interactions between the hippocampus and cortex during sleep are thought to be critical for this process of ..
- Neurophysiology and Anatomy of Multisensory ProcessingCharles E Schroeder; Fiscal Year: 2013DESCRIPTION (provided by applicant): Multisensory Integration begins at or before the level of primary auditory cortex (A1) and builds over higher stages...
- FUNCTIONS OF NICOTINE RECEPTORS IN SENSORY NEOCORTEXRaju Metherate; Fiscal Year: 2012..a potential cellular link: functional impairment of nicotinic acetylcholine receptors (nAChRs) in primary auditory cortex (A1)...
- The Neural Correlates and Mechanisms of Spatial Stream Segregation in Rat PrimaryJUSTIN DANIEL YAO; Fiscal Year: 2013..stream segregation, we propose three specific aims: 1) Evaluate the spatial sensitivity of rat primary auditory cortex (A1);2) Characterize spatial stream segregation in rat A1;3) Determine the neural mechanisms of spatial ..
- Neuronal oscillations as a tool for attentional stream selectionElana Zion Golumbic; Fiscal Year: 2013..these ideas, I will record electroencephalographic (EEG) signals from implanted electrodes in and surrounding auditory cortex in surgical epilepsy patients, while they engage in a series of auditory stream selection tasks...
- Impact of early auditory training on developemental hearing lossEMMA CHRISTINE SARRO; Fiscal Year: 2010..How neural coding properties in auditory cortex (ACx) respond to early sensory experience will then be correlated to behavioral performance...
- Functional Neuroimaging and Transcranial Magnetic Stimulation in Mal de DebarquemYOON HEE K CHA; Fiscal Year: 2012..Studies on tinnitus show that there is an area of heightened baseline activity in the auditory cortex and that this activity can be dampened with rTMS...
- Phonetic influences on auditory feedback controlCaroline Niziolek; Fiscal Year: 2013..On the other hand, a speaker may monitor his output at a sub-categorical level, before high-level auditory cortex imposes phonetic structure on the acoustic signal...
- CORTICAL REPRESENTATION OF AUDITORY SPACEJohn C Middlebrooks; Fiscal Year: 2012..It will test the hypothesis that informational masking arises at the level of auditory cortex and that spatial masking release is enhanced in auditory cortical belt areas...
- Targeted Neural Plasticity for the Treatment of TinnitusRichard S Tyler; Fiscal Year: 2013..The tinnitus field generally accepts that elevated synchronous spontaneous activity in the auditory cortex may account for the tinnitus percept that arises following hearing loss...
- Animal Model of Speech Sound Processing in AutismMichael P Kilgard; Fiscal Year: 2013..that in utero VPA exposure severely degrades the precise spatiotemporal patterns evoked by speech sounds in auditory cortex. As in autism, the longer latency in our animal model is significantly greater for speech sounds compared to ..
- Neurophysiology of somatosensory influences on auditory cortical processingGabriella Musacchia; Fiscal Year: 2010..questions by characterizing how vibrotactile inputs impact on the discriminative processing of sounds in auditory cortex. I will record neuronal activity from depth electrodes placed in primary and non-primary auditory cortices of ..
- Effects of Spectral Context on Responses in Auditory CortexDENNIS BARBOUR; Fiscal Year: 2009..and communication sound encoding in the mammalian auditory system by evaluating how neurons in primate auditory cortex integrate sound energy over a wide range of frequencies...
- The role of dendrite-targeting interneurons in auditory cortexBRYAN SEYBOLD; Fiscal Year: 2013....
- Neural Correlates of Auditory ContinuityPOPPY A CRUM; Fiscal Year: 2010..This proposal aims to study the neural correlates of auditory continuity in single neurons in the auditory cortex of the awake behaving common marmoset (Callithrix Jacchus) to understand how patterns of neural response ..
- Organization and experience-dependence of auditory coding in forebrainALLISON JANE DOUPE; Fiscal Year: 2013..hierarchical network of auditory areas that sub serve these tasks, including the avian equivalent of primary auditory cortex, field L, and several secondary areas that are the likely equivalent of belt cortex...
- FUNCTIONS OF NICOTINE RECEPTORS IN SENSORY NEOCORTEXRaju Metherate; Fiscal Year: 2013..We hypothesize that activation of nAChRs will narrow RF tuning in primary auditory cortex (A1) and enhance processing within narrowed RFs, and that these cellular actions of nAChRs contribute to ..
- The Neural Basis of Perceptually-Relevant Auditory Modulations in HumansJonathan Z Simon; Fiscal Year: 2012..neuroscience is to understand how speech and other natural sounds are analyzed and encoded in the human auditory cortex. One major finding is that perception and speech processing are crucially affected by temporal modulations in ..
- Role of serotonin in auditory cortex regulation following early-onset sensorineurGREGORY BASURA; Fiscal Year: 2009..Hearing impairments during early postnatal development produce significant changes in the human auditory cortex that may permanently diminish auditory perceptual skills and compromise language acquisition (Psarommatis et ..
- HUMAN AUDITORY CORTEX PHYSIOLOGYMatthew Howard; Fiscal Year: 2000The unifying focus of the proposed research is the study of human auditory cortex. The two specific areas of investigation will be: l) Cellular electrophysiology of human auditory cortex, 2) Feasibility studies of an auditory cortex ..
- Cortical Sensitivity to Acoustic Cues for Sound LocationEWAN MACPHERSON; Fiscal Year: 2006..Sound localization is a fundamental task of the auditory system, and in higher mammals, requires an intact auditory cortex. Many cortical neurons respond over broad regions of space and vary the rate and temporal pattern of their ..
- Feature selectivity of auditory thalamusEdward Bartlett; Fiscal Year: 2005..arise from the MGB representations, given the comparatively large body of knowledge regarding responses of auditory cortex neurons to auditory stimuli...
- Technological Development Towards a Cortical ProsthesisPatrick Rousche; Fiscal Year: 2005..Preliminary evidence suggests that direct electrical stimulation of the human auditory cortex can induce auditory perceptions...
- Cortical Electrical Suppression of Noise-Induced TinnitusJinsheng Zhang; Fiscal Year: 2010..Among numerous management strategies being sought, auditory cortex electrical stimulation (ACES) has recently been used clinically to suppress tinnitus...
- ACTIVITY OF AI NEURONS IN LOCALIZING SOUNDSGregg Recanzone; Fiscal Year: 2000..An apparent paradox exists, where lesions of the auditory cortex result in profound sound localization deficits, but the spatial selectivity of most cells in auditory cortex ..
- Functional organization of auditory corticothalamic projection systemsDaniel Llano; Fiscal Year: 2007..Summary: The objective of the proposed studies is to understand the functional relationships between the auditory cortex and thalamus, and ultimately to uncover the neural substrates for auditory cognition...
- PARALLEL AUDITORY PATHWAYS IN THE BRAIN STEMEllen Covey; Fiscal Year: 2006..multiple auditory centers in the lower brainstem, from non-ascending auditory inputs from the opposite IC and auditory cortex and from motor-related structures...
- STRUCTURE OF PRIMARY AUDITORY CORTEXJEFFERY WINER; Fiscal Year: 1993This is a proposal to study the structure, connections, and neurochemical organization of the primary auditory cortex (AI), medial geniculate body, and inferior colliculus in several species...
- Optogenetic analysis of circuits for vocal recognitionRichard Mooney; Fiscal Year: 2009..Most of these conditions involve damage or dysfunction in the auditory cortex, indicating that this structure plays an essential role in vocal perception...
- CRCNS: Dynamics of the auditory cortical columnGyorgy Buzsaki; Fiscal Year: 2012DESCRIPTION (provided by applicant): The auditory cortex is a critical structure for processing of sound information in mammals...
- Single-unit response to AM sound in the auditory cortex.Mamiko Niwa; Fiscal Year: 2009..We will record single-units responses in the primary auditory cortex (A1) and the middle-lateral field of the auditory cortex (ML) of non-human subjects while they actively ..
- CORTICAL REPRESENTATION OF AUDITORY SPACEJOHN MIDDLEBROOKS; Fiscal Year: 1991Clinical and animal studies indicate that lesions of the auditory cortex can result in deficits in the ability to localize a sound...
- Functional neuroanatomy of auditory object perceptionAmber Leaver; Fiscal Year: 2009..in visual neuroscience, leaving significant gaps in our understanding of functional organization of human auditory cortex. The work proposed here will answer important questions regarding representation of auditory objects (i.e...
- Targeted Neural Plasticity for the Treatment of TinnitusNAVZER ENGINEER; Fiscal Year: 2009..Recent studies suggest that pathological reorganization of frequency mapping in the auditory cortex is a major contributor to the symptoms of tinnitus in many patients...