auditory cortex

Summary

Summary: Area of the temporal lobe concerned with hearing.

Top Publications

  1. ncbi Increased auditory cortical representation in musicians
    C Pantev
    Biomagnetism Center, Institute of Experimental Audiology, University of Munster, Germany
    Nature 392:811-4. 1998
  2. pmc Dichotomy of functional organization in the mouse auditory cortex
    Sharba Bandyopadhyay
    Department of Biology, University of Maryland, College Park, Maryland, USA
    Nat Neurosci 13:361-8. 2010
  3. ncbi Sensitivity of newborn auditory cortex to the temporal structure of sounds
    Silke Telkemeyer
    Berlin NeuroImaging Center, Charite University Medicine, 10117 Berlin, Germany
    J Neurosci 29:14726-33. 2009
  4. ncbi Correlating stimulus-specific adaptation of cortical neurons and local field potentials in the awake rat
    Wolfger von der Behrens
    Institute for Cell Biology and Neuroscience, Department of Biological Sciences, Goethe University, Frankfurt am Main, Germany
    J Neurosci 29:13837-49. 2009
  5. ncbi Spectral interactions, but no mismatch negativity, in auditory cortex of anesthetized rat
    Ronit Lazar
    Department of Neurobiology and Behavior, University of California, Irvine, 2205 McGaugh Hall, Irvine, CA 92697, USA
    Hear Res 181:51-6. 2003
  6. pmc Maps and streams in the auditory cortex: nonhuman primates illuminate human speech processing
    Josef P Rauschecker
    Laboratory of Integrative Neuroscience and Cognition, Georgetown University Medical Center, Washington, DC, USA
    Nat Neurosci 12:718-24. 2009
  7. doi A disinhibitory microcircuit for associative fear learning in the auditory cortex
    Johannes J Letzkus
    Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH 4058 Basel, Switzerland
    Nature 480:331-5. 2011
  8. pmc Mechanisms and streams for processing of "what" and "where" in auditory cortex
    J P Rauschecker
    Georgetown Institute for Cognitive and Computational Sciences, Georgetown University Medical Center, Washington, DC 20007, USA
    Proc Natl Acad Sci U S A 97:11800-6. 2000
  9. ncbi The processing of temporal pitch and melody information in auditory cortex
    Roy D Patterson
    Centre for the Neural Basis of Hearing, Physiology Department, University of Cambridge, Downing Street, Cambridge, United Kingdom
    Neuron 36:767-76. 2002
  10. pmc Tinnitus intensity dependent gamma oscillations of the contralateral auditory cortex
    Elsa van der Loo
    Brain Research centre Antwerp for Innovative and Interdisciplinary Neuromodulation BRAI 2 N, University Hospital Antwerp, Antwerp, Belgium
    PLoS ONE 4:e7396. 2009

Detail Information

Publications318 found, 100 shown here

  1. ncbi Increased auditory cortical representation in musicians
    C Pantev
    Biomagnetism Center, Institute of Experimental Audiology, University of Munster, Germany
    Nature 392:811-4. 1998
    ....
  2. pmc Dichotomy of functional organization in the mouse auditory cortex
    Sharba Bandyopadhyay
    Department of Biology, University of Maryland, College Park, Maryland, USA
    Nat Neurosci 13:361-8. 2010
    ..The gradient of frequency selectivity (tonotopy) is the dominant organizational feature in the primary auditory cortex, whereas other feature-based organizations are less well established...
  3. ncbi Sensitivity of newborn auditory cortex to the temporal structure of sounds
    Silke Telkemeyer
    Berlin NeuroImaging Center, Charite University Medicine, 10117 Berlin, Germany
    J Neurosci 29:14726-33. 2009
    ..That is, the newborn auditory cortex is sensitive to the temporal structure of the auditory input and shows an emerging tendency for functional ..
  4. ncbi Correlating stimulus-specific adaptation of cortical neurons and local field potentials in the awake rat
    Wolfger von der Behrens
    Institute for Cell Biology and Neuroscience, Department of Biological Sciences, Goethe University, Frankfurt am Main, Germany
    J Neurosci 29:13837-49. 2009
    ..Stimulus-specific adaptation (SSA) of single neurons in the auditory cortex has been proposed to be the cellular substrate of MMN (Nelken and Ulanovsky, 2007)...
  5. ncbi Spectral interactions, but no mismatch negativity, in auditory cortex of anesthetized rat
    Ronit Lazar
    Department of Neurobiology and Behavior, University of California, Irvine, 2205 McGaugh Hall, Irvine, CA 92697, USA
    Hear Res 181:51-6. 2003
    We used an 'oddball' stimulation paradigm to evoke epidural, event-related potentials over auditory cortex in urethane/xylazine-anesthetized rats, in order to study the neural mechanisms underlying the mismatch negativity (MMN)...
  6. pmc Maps and streams in the auditory cortex: nonhuman primates illuminate human speech processing
    Josef P Rauschecker
    Laboratory of Integrative Neuroscience and Cognition, Georgetown University Medical Center, Washington, DC, USA
    Nat Neurosci 12:718-24. 2009
    ..Chief among these are physiological and anatomical studies showing that primate auditory cortex, across species, shows patterns of hierarchical structure, topographic mapping and streams of functional ..
  7. doi A disinhibitory microcircuit for associative fear learning in the auditory cortex
    Johannes J Letzkus
    Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH 4058 Basel, Switzerland
    Nature 480:331-5. 2011
    ..of associative fear memories depends on the recruitment of a disinhibitory microcircuit in the mouse auditory cortex. Fear-conditioning-associated disinhibition in auditory cortex is driven by foot-shock-mediated cholinergic ..
  8. pmc Mechanisms and streams for processing of "what" and "where" in auditory cortex
    J P Rauschecker
    Georgetown Institute for Cognitive and Computational Sciences, Georgetown University Medical Center, Washington, DC 20007, USA
    Proc Natl Acad Sci U S A 97:11800-6. 2000
    The functional specialization and hierarchical organization of multiple areas in rhesus monkey auditory cortex were examined with various types of complex sounds...
  9. ncbi The processing of temporal pitch and melody information in auditory cortex
    Roy D Patterson
    Centre for the Neural Basis of Hearing, Physiology Department, University of Cambridge, Downing Street, Cambridge, United Kingdom
    Neuron 36:767-76. 2002
    ..The results support the view that there is hierarchy of pitch processing in which the center of activity moves anterolaterally away from primary auditory cortex as the processing of melodic sounds proceeds.
  10. pmc Tinnitus intensity dependent gamma oscillations of the contralateral auditory cortex
    Elsa van der Loo
    Brain Research centre Antwerp for Innovative and Interdisciplinary Neuromodulation BRAI 2 N, University Hospital Antwerp, Antwerp, Belgium
    PLoS ONE 4:e7396. 2009
    ..Tinnitus as a phantom phenomenon is related to hyperactivity and reorganization of the auditory cortex. Magnetoencephalography studies demonstrate a correlation between gamma band activity in the contralateral ..
  11. ncbi Rapid task-related plasticity of spectrotemporal receptive fields in primary auditory cortex
    Jonathan Fritz
    Center for Auditory and Acoustic Research, Institute for Systems Research, Electrical and Computer Engineering, University of Maryland, College Park, Maryland 20742, USA
    Nat Neurosci 6:1216-23. 2003
    ..We recorded neuronal responses in the primary auditory cortex of behaving ferrets that were trained to detect a target tone of any frequency...
  12. pmc Synaptic mechanisms of direction selectivity in primary auditory cortex
    Chang quan Ye
    Institute of Neuroscience and State Key Laboratory of Neuroscience, Chinese Academy of Sciences, Shanghai 200031, China
    J Neurosci 30:1861-8. 2010
    ..Although many neurons in the auditory cortex are known to be selective for FM direction, the synaptic mechanisms underlying this selectivity are not well ..
  13. pmc Stimulus-specific adaptation in the auditory thalamus of the anesthetized rat
    Flora M Antunes
    Auditory Neurophysiology Unit, Laboratory for the Neurobiology of Hearing, Institute of Neuroscience of Castilla y Leon, University of Salamanca, Salamanca, Spain
    PLoS ONE 5:e14071. 2010
    ..Previous studies have demonstrated that neurons in the auditory cortex and inferior colliculus show SSA...
  14. ncbi How the brain separates sounds
    Robert P Carlyon
    MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 2EF, UK
    Trends Cogn Sci 8:465-71. 2004
    ..Listeners' sensitivity to streaming cues can be captured in the responses of neurons in the primary auditory cortex, and in EEG wave components with a short latency (< 200ms)...
  15. ncbi Processing of low-probability sounds by cortical neurons
    Nachum Ulanovsky
    Department of Physiology, Hebrew University, Hadassah Medical School, Box 12272, Jerusalem 91120, Israel
    Nat Neurosci 6:391-8. 2003
    ..We report here that neurons in cat primary auditory cortex (A1) responded more strongly to a rarely presented sound than to the same sound when it was common...
  16. ncbi Multiple time scales of adaptation in auditory cortex neurons
    Nachum Ulanovsky
    Department of Neurobiology, The Alexander Silberman Institute of Life Sciences, Hebrew University, Jerusalem 91904, Israel
    J Neurosci 24:10440-53. 2004
    Neurons in primary auditory cortex (A1) of cats show strong stimulus-specific adaptation (SSA)...
  17. pmc Auditory cortex tracks both auditory and visual stimulus dynamics using low-frequency neuronal phase modulation
    Huan Luo
    State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    PLoS Biol 8:e1000445. 2010
    ....
  18. ncbi Changes in spontaneous firing rate and neural synchrony in cat primary auditory cortex after localized tone-induced hearing loss
    Satoshi Seki
    Departments of Physiology and Biophysics, and Psychology, University of Calgary, 2500 University Drive N W, Calgary, AB, Canada T2N 1N4
    Hear Res 180:28-38. 2003
    ..The frequency representation in primary auditory cortex was mapped using an eight-electrode array. Single-unit spontaneous activity was recorded for 15 min...
  19. doi "Who" is saying "what"? Brain-based decoding of human voice and speech
    Elia Formisano
    Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, University of Maastricht, 6200 MD Maastricht, Netherlands
    Science 322:970-3. 2008
    ..a person is listening to from the neural fingerprints that speech and voice signals elicit in the listener's auditory cortex. These cortical fingerprints are spatially distributed and insensitive to acoustic variations of the input so ..
  20. pmc Phase patterns of neuronal responses reliably discriminate speech in human auditory cortex
    Huan Luo
    Neuroscience and Cognitive Science Program, Department of Biology, University of Maryland College Park, College Park, MD 20742, USA
    Neuron 54:1001-10. 2007
    How natural speech is represented in the auditory cortex constitutes a major challenge for cognitive neuroscience...
  21. ncbi Visual modulation of neurons in auditory cortex
    Christoph Kayser
    Max Planck Institute for Biological Cybernetics, Spemannstrasse 38, 72076 Tubingen, Germany
    Cereb Cortex 18:1560-74. 2008
    ..These results demonstrate that visual stimuli can modulate the firing of neurons in auditory cortex in a manner that depends on stimulus efficacy and timing...
  22. pmc Residual inhibition functions overlap tinnitus spectra and the region of auditory threshold shift
    Larry E Roberts
    Department of Psychology, Neuroscience, and Behaviour, McMaster University, 1280 Main Street West, Hamilton, ON, Canada, L8S 4K1
    J Assoc Res Otolaryngol 9:417-35. 2008
    ..Animals exposed to noise trauma show augmented synchronous neural activity in tonotopically reorganized primary auditory cortex consequent on hearing loss...
  23. pmc Laminar structure of spontaneous and sensory-evoked population activity in auditory cortex
    Shuzo Sakata
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
    Neuron 64:404-18. 2009
    ..cells, we compare the laminar structure of spontaneous and sensory-evoked population activity in rat auditory cortex. Spontaneous and evoked patterns both exhibited sparse, spatially localized activity in layer 2/3 pyramidal ..
  24. pmc Interactions between the superior temporal sulcus and auditory cortex mediate dynamic face/voice integration in rhesus monkeys
    Asif A Ghazanfar
    Neuroscience Institute and Department of Psychology, Princeton University, Princeton, New Jersey 08540, USA
    J Neurosci 28:4457-69. 2008
    ..To test the hypothesis that multisensory responses in auditory cortex are influenced by visual inputs from the superior temporal sulcus (STS), an association area, we recorded ..
  25. ncbi Dynamics of precise spike timing in primary auditory cortex
    Mounya Elhilali
    Institute for Systems Research, Department of Electrical and Computer Engineering, University of Maryland, College Park, Maryland 20742, USA
    J Neurosci 24:1159-72. 2004
    Although single units in primary auditory cortex (A1) exhibit accurate timing in their phasic response to the onset of sound (precision of a few milliseconds), paradoxically, they are unable to sustain synchronized responses to repeated ..
  26. pmc Attention-driven auditory cortex short-term plasticity helps segregate relevant sounds from noise
    Jyrki Ahveninen
    Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 108:4182-7. 2011
    ..In conclusion, a simple gain model alone cannot explain auditory selective attention. In nonprimary auditory cortices, attention-driven short-term plasticity retunes neurons to segregate relevant sounds from noise...
  27. doi Cortical map plasticity improves learning but is not necessary for improved performance
    Amanda Reed
    School of Behavioral and Brain Sciences, GR41, The University of Texas at Dallas, Richardson, TX 75080 3021, USA
    Neuron 70:121-31. 2011
    ..in perceptual ability after pairing tones with stimulation of the cholinergic nucleus basalis to induce auditory cortex map plasticity outside of a behavioral context...
  28. doi Prior expectation mediates neural adaptation to repeated sounds in the auditory cortex: an MEG study
    Ana Todorović
    Donders Institute for Brain, Cognition, and Behaviour, Radboud University Nijmegen, 6500 HB Nijmegen, The Netherlands
    J Neurosci 31:9118-23. 2011
    ..We found robust repetition suppression in the auditory cortex for repeated tones...
  29. pmc Projections to the inferior colliculus from layer VI cells of auditory cortex
    B R Schofield
    Department of Anatomy and Neurobiology, Northeastern Ohio Universities College of Medicine, 4209 State Route 44, PO Box 95, Rootstown, OH 44272, USA
    Neuroscience 159:246-58. 2009
    ..a retrograde tracer into the inferior colliculus of guinea pigs labeled two bands of cells in the ipsilateral auditory cortex: a dense band of cells in layer V and a second band of cells in layer VI...
  30. pmc Spatial and temporal processing of single auditory cortical neurons and populations of neurons in the macaque monkey
    Gregg H Recanzone
    Center for Neuroscience, Department of Neurobiology, Physiology and Behavior, University of California at Davis, One Shields Avenue, Davis, CA 95616, USA
    Hear Res 271:115-22. 2011
    The auditory cortex is known to be a necessary neural structure for the perception of acoustic signals, particularly the spatial location and the temporal features of complex auditory stimuli...
  31. ncbi Sensory-motor interaction in the primate auditory cortex during self-initiated vocalizations
    Steven J Eliades
    Laboratory of Auditory Neurophysiology, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurophysiol 89:2194-207. 2003
    Little is known about sensory-motor interaction in the auditory cortex of primates at the level of single neurons and its role in supporting vocal communication...
  32. ncbi Physiological and anatomical evidence for multisensory interactions in auditory cortex
    Jennifer K Bizley
    Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford OX1 3PT, UK
    Cereb Cortex 17:2172-89. 2007
    ..recordings and estimates of mutual information that visual stimuli can influence the activity of units in the auditory cortex of anesthetized ferrets...
  33. ncbi Synaptic mechanisms of forward suppression in rat auditory cortex
    Michael Wehr
    Cold Spring Harbor Laboratory, New York 11724, USA
    Neuron 47:437-45. 2005
    In the auditory cortex, brief sounds elicit a powerful suppression of responsiveness that can persist for hundreds of milliseconds...
  34. ncbi Spectral and temporal processing in human auditory cortex
    R J Zatorre
    Montreal Neurological Institute, McGill University, 3801 University St, Montreal, QC H3A 2B4, Canada
    Cereb Cortex 11:946-53. 2001
    We used positron emission tomography to examine the response of human auditory cortex to spectral and temporal variation...
  35. pmc Developmental sensory experience balances cortical excitation and inhibition
    Anja L Dorrn
    Department of Neuroscience, Max Delbruck Center for Molecular Medicine, and NeuroCure Neuroscience Research Center NWFZ, Berlin 13125, Germany
    Nature 465:932-6. 2010
    Early in life, neural circuits are highly susceptible to outside influences. The organization of the primary auditory cortex (A1) in particular is governed by acoustic experience during the critical period, an epoch near the beginning of ..
  36. ncbi Auditory cortex on the human posterior superior temporal gyrus
    M A Howard
    Department of Surgery Division of Neurosurgery, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    J Comp Neurol 416:79-92. 2000
    ..These physiological findings are in accord with anatomic evidence in humans and in nonhuman primates that the superior temporal cortex contains multiple interconnected auditory areas...
  37. pmc GABA shapes selectivity for the rate and direction of frequency-modulated sweeps in the auditory cortex
    Khaleel A Razak
    Department 3166, Zoology and Physiology, University of Wyoming, 1000 E University Ave, Laramie, WY 82071, USA
    J Neurophysiol 102:1366-78. 2009
    In the pallid bat auditory cortex and inferior colliculus (IC), the majority of neurons tuned in the echolocation range is selective for the direction and rate of frequency-modulated (FM) sweeps used in echolocation...
  38. doi Visual enhancement of the information representation in auditory cortex
    Christoph Kayser
    Max Planck Institute for Biological Cybernetics, Spemannstrasse 38, 72076 Tubingen, Germany
    Curr Biol 20:19-24. 2010
    ..By recording in auditory cortex of alert monkeys watching naturalistic audiovisual stimuli, we quantified the effect of visual influences on ..
  39. ncbi A synaptic memory trace for cortical receptive field plasticity
    Robert C Froemke
    Coleman Memorial Laboratory and W M Keck Foundation Center for Integrative Neuroscience, Department of Otolaryngology, University of California, San Francisco, California 94143, USA
    Nature 450:425-9. 2007
    ..Here we determine the dynamics of synaptic receptive field plasticity in the adult primary auditory cortex (also known as AI) using in vivo whole-cell recording...
  40. doi Mismatch negativity (MMN), the deviance-elicited auditory deflection, explained
    Patrick J C May
    Department of Biomedical Engineering and Computational Science, Helsinki University of Technology, Espoo, Finland
    Psychophysiology 47:66-122. 2010
    ..We propose that the MMN is, in essence, a latency- and amplitude-modulated expression of the auditory N1 response, generated by fresh-afferent activity of cortical neurons that are under nonuniform levels of adaptation...
  41. ncbi Non-sensory cortical and subcortical connections of the primary auditory cortex in Mongolian gerbils: bottom-up and top-down processing of neuronal information via field AI
    Eike Budinger
    Leibniz Institute for Neurobiology, Department of Auditory Learning and Speech, Brenneckestrasse 6, D 39118 Magdeburg, Germany
    Brain Res 1220:2-32. 2008
    In the present study, we will provide further anatomical evidence that the primary auditory cortex (field AI) is not only involved in sensory processing of its own modality, but also in complex bottom-up and top-down processing of ..
  42. doi The mechanisms of tinnitus: perspectives from human functional neuroimaging
    Peyman Adjamian
    MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, United Kingdom
    Hear Res 253:15-31. 2009
    ....
  43. ncbi Suppressed responses to self-triggered sounds in the human auditory cortex
    Mika H Martikainen
    Department of Clinical Neurophysiology, Helsinki University Central Hospital, FIN 00290 Helsinki, Finland
    Cereb Cortex 15:299-302. 2005
    ..Here we tested whether responses in the human auditory cortex would differ to self-triggered versus externally triggered tones...
  44. ncbi Activity associated with stream segregation in human auditory cortex is similar for spatial and pitch cues
    Stefan Schadwinkel
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, Heidelberg, Germany
    Cereb Cortex 20:2863-73. 2010
    ..and potential neural correlates for streaming based on spectral and pitch cues have been identified in the auditory cortex. Here, magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) were used to evaluate if ..
  45. pmc Contrast gain control in auditory cortex
    Neil C Rabinowitz
    Department of Physiology, Anatomy, and Genetics, Sherrington Building, Parks Road, University of Oxford, Oxford OX13PT, UK
    Neuron 70:1178-91. 2011
    ..We show that neurons in ferret auditory cortex rescale their gain to partially compensate for the spectrotemporal contrast of recent stimulation...
  46. pmc Functional connectivity and cholinergic modulation in auditory cortex
    Raju Metherate
    Department of Neurobiology and Behavior, Center for Hearing Research, University of California Irvine, CA 92697 4550, United States
    Neurosci Biobehav Rev 35:2058-63. 2011
    Although it is known that primary auditory cortex (A1) contributes to the processing and perception of sound, its precise functions and the underlying mechanisms are not well understood...
  47. doi Human primary auditory cortex follows the shape of Heschl's gyrus
    Sandra Da Costa
    Neuropsychology and Neurorehabilitation Service, Lausanne University Hospital CHUV, Switzerland
    J Neurosci 31:14067-75. 2011
    The primary auditory cortex (PAC) is central to human auditory abilities, yet its location in the brain remains unclear...
  48. doi Effect of auditory cortex deactivation on stimulus-specific adaptation in the medial geniculate body
    Flora M Antunes
    Auditory Neurophysiology Unit, Laboratory for the Neurobiology of Hearing, Institute of Neuroscience of Castilla y Leon, Calle Pintor Fernando Gallego, 1, Spain
    J Neurosci 31:17306-16. 2011
    ..In the auditory system, SSA has been identified in the midbrain, thalamus, and auditory cortex (AC)...
  49. pmc Neural activity in speech-sensitive auditory cortex during silence
    M D Hunter
    Sheffield Cognition and Neuroimaging Laboratory SCANLab, Academic Clinical Psychiatry, Division of Genomic Medicine, University of Sheffield, Sheffield S5 7JT, United Kingdom
    Proc Natl Acad Sci U S A 103:189-94. 2006
    ..heard in the absence of external stimuli implies the existence of endogenous neural activity within the auditory cortex responsible for their perception...
  50. ncbi Redefining the tonotopic core of rat auditory cortex: physiological evidence for a posterior field
    Neot N Doron
    W M Keck Laboratories of Neurobiology, Center for Neural Science, New York University, New York, New York 10003, USA
    J Comp Neurol 453:345-60. 2002
    ..Finally, the physiological data suggest that core auditory cortex (temporal area TE1) is composed not only of AI as previously thought, but also of at least two other ..
  51. doi Cross-modal plasticity in specific auditory cortices underlies visual compensations in the deaf
    Stephen G Lomber
    Centre for Brain and Mind, Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada
    Nat Neurosci 13:1421-7. 2010
    ..In the absence of acoustic input, it has been proposed that cross-modal reorganization of deaf auditory cortex may provide the neural substrate mediating compensatory visual function...
  52. ncbi Birdsong memory: a neural dissociation between song recognition and production
    Sharon M H Gobes
    Behavioural Biology and Helmholtz Institute, Utrecht University, Padualaan 8, P O Box 80086, 3508 TB Utrecht, The Netherlands
    Curr Biol 17:789-93. 2007
    ..Thus, in both humans and songbirds, the cognitive systems of vocal production and auditory recognition memory are subserved by distinct brain regions...
  53. pmc Encoding of learned importance of sound by magnitude of representational area in primary auditory cortex
    Richard G Rutkowski
    Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697 3800, USA
    Proc Natl Acad Sci U S A 102:13664-9. 2005
    We hypothesized that learning-induced representational expansion in the primary auditory cortex (AI) directly encodes the degree of behavioral importance of a sound...
  54. doi Sound categories are represented as distributed patterns in the human auditory cortex
    Noel Staeren
    Faculty of Psychology and Neuroscience, Department of Cognitive Neuroscience, University of Maastricht, 6200 MD Maastricht, The Netherlands
    Curr Biol 19:498-502. 2009
    ....
  55. ncbi Binary spiking in auditory cortex
    Michael R Deweese
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
    J Neurosci 23:7940-9. 2003
    ..We have, therefore, assessed trial-to-trial variability in the auditory cortex of the rat. To ensure single-unit isolation, we used cell-attached recording...
  56. ncbi Auditory plasticity and hyperactivity following cochlear damage
    R J Salvi
    Hearing Research Lab, University of Buffalo, 215 Parker Hall, Buffalo, NY 14214, USA
    Hear Res 147:261-74. 2000
    ..of IHC loss, the IC response shows only a modest amplitude reduction, and remarkably, the response of the auditory cortex is enhanced...
  57. pmc Early auditory experience generates long-lasting memories that may subserve vocal learning in songbirds
    Mimi L Phan
    Department of Psychology, Rutgers University, Piscataway, NJ 08854, USA
    Proc Natl Acad Sci U S A 103:1088-93. 2006
    ..Furthermore, the strength of this selectivity shows a striking correlation with the fidelity of vocal imitation, suggesting that this auditory memory may have served as the model for song learning...
  58. pmc Stimulus-specific adaptation and deviance detection in the rat auditory cortex
    Nevo Taaseh
    Department of Neurobiology, Silberman Institute of Life Sciences, Hebrew University, Jerusalem, Israel
    PLoS ONE 6:e23369. 2011
    ..We studied SSA in the auditory cortex of halothane-anesthetized rats, recording local field potentials and multi-unit activity...
  59. ncbi An oscillatory hierarchy controlling neuronal excitability and stimulus processing in the auditory cortex
    Peter Lakatos
    Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Inst, Orangeburg, New York 10962, USA
    J Neurophysiol 94:1904-11. 2005
    ..current source density CSD] and multiunit activity (MUA), both spontaneous and stimulus-driven, in primary auditory cortex of awake macaque monkeys...
  60. pmc Listening to tailor-made notched music reduces tinnitus loudness and tinnitus-related auditory cortex activity
    Hidehiko Okamoto
    Institute for Biomagnetism and Biosignalanalysis, Westfalian Wilhelms University, Malmedyweg 15, Muenster, Germany
    Proc Natl Acad Sci U S A 107:1207-10. 2010
    Maladaptive auditory cortex reorganization may contribute to the generation and maintenance of tinnitus...
  61. pmc Cortical representation of natural complex sounds: effects of acoustic features and auditory object category
    Amber M Leaver
    Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC 20057, USA
    J Neurosci 30:7604-12. 2010
    ..sounds are thought to be represented by neurons responding to increasing degrees of complexity throughout auditory cortex, with complete auditory "objects" encoded by neurons (or small networks of neurons) in anterior superior ..
  62. ncbi Relationship of imprecise corollary discharge in schizophrenia to auditory hallucinations
    Theda H Heinks-Maldonado
    Department of Neuropsychology, Albert Ludwigs Universitat, Freiburg, Germany
    Arch Gen Psychiatry 64:286-96. 2007
    ..Imprecision of the corollary discharge in schizophrenia may contribute to the misperception of inner experiences and thoughts as "voices" or auditory hallucinations...
  63. pmc Rapid synaptic depression explains nonlinear modulation of spectro-temporal tuning in primary auditory cortex by natural stimuli
    Stephen V David
    Institute for Systems Research, University of Maryland, College Park, Maryland 20742, USA
    J Neurosci 29:3374-86. 2009
    In this study, we explored ways to account more accurately for responses of neurons in primary auditory cortex (A1) to natural sounds...
  64. ncbi Human primary auditory cortex: cytoarchitectonic subdivisions and mapping into a spatial reference system
    P Morosan
    Institute of Medicine, , Germany
    Neuroimage 13:684-701. 2001
    The transverse temporal gyrus of Heschl contains the human auditory cortex. Several schematic maps of the cytoarchitectonic correlate of this functional entity are available, but they present partly conflicting data (number and position ..
  65. pmc Sparse representation of sounds in the unanesthetized auditory cortex
    Tomás Hromádka
    Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Cold Spring Harbor, New York, United States of America
    PLoS Biol 6:e16. 2008
    How do neuronal populations in the auditory cortex represent acoustic stimuli? Although sound-evoked neural responses in the anesthetized auditory cortex are mainly transient, recent experiments in the unanesthetized preparation have ..
  66. ncbi Morphology of Heschl's gyrus reflects enhanced activation in the auditory cortex of musicians
    Peter Schneider
    Department of Physics, University of Heidelberg, Philosophenweg 12, D 69120 Heidelberg, Germany
    Nat Neurosci 5:688-94. 2002
    Using magnetoencephalography (MEG), we compared the processing of sinusoidal tones in the auditory cortex of 12 non-musicians, 12 professional musicians and 13 amateur musicians...
  67. ncbi Perceptual learning directs auditory cortical map reorganization through top-down influences
    Daniel B Polley
    W M Keck Foundation Center for Integrative Neuroscience, Department of Otolaryngology, University of California, San Francisco, California 94143 0732, USA
    J Neurosci 26:4970-82. 2006
    ..We tested whether topographic map plasticity in the adult primary auditory cortex and a secondary auditory area, the suprarhinal auditory field, was controlled by the statistics of bottom-up ..
  68. ncbi Temporal and rate representations of time-varying signals in the auditory cortex of awake primates
    T Lu
    Laboratory of Auditory Neurophysiology, Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 424, Baltimore, Maryland 21205, USA
    Nat Neurosci 4:1131-8. 2001
    ..Here we show that there are two largely distinct populations of neurons in the auditory cortex of awake primates: one with stimulus-synchronized discharges that, with a temporal code, explicitly ..
  69. ncbi Perceptual organization of tone sequences in the auditory cortex of awake macaques
    Christophe Micheyl
    Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Neuron 48:139-48. 2005
    ..formation measured in humans using alternating-tone sequences can be quantitatively accounted for based on single-unit responses recorded in the primary auditory cortex (A1) of awake rhesus monkeys listening to the same sound sequences.
  70. ncbi Impaired mismatch negativity (MMN) generation in schizophrenia as a function of stimulus deviance, probability, and interstimulus/interdeviant interval
    D C Javitt
    Nathan Kline Institute for Psychiatric Research New York University School of Medicine, Orangeburg 10962, USA
    Electroencephalogr Clin Neurophysiol 108:143-53. 1998
    ..The pattern of deficit observed in schizophrenia differs from the pattern observed in other conditions associated with MMN dysfunction, including Alzheimer's disease, stroke, and alcohol intoxication...
  71. ncbi The structure and physiology of the rat auditory system: an overview
    Manuel S Malmierca
    Laboratory for the Neurobiology of Hearing, Department of Cellular Biology and Pathology, Faculty of Medicine, University of Salamanca, Institute for Neuroscience of Castilla y León, Campus Miguel de Unamuno, 37007 Salamanca, Spain
    Int Rev Neurobiol 56:147-211. 2003
  72. pmc State-dependent representation of amplitude-modulated noise stimuli in rat auditory cortex
    Stephan L Marguet
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, New Jersey 07102, USA
    J Neurosci 31:6414-20. 2011
    ..stimulus was repeatedly presented while recording neuronal populations and local field potentials (LFPs) in auditory cortex of urethane-anesthetized rats...
  73. pmc Tinnitus suppression by low-rate electric stimulation and its electrophysiological mechanisms
    Fan Gang Zeng
    Department of Otolaryngology Head and Neck Surgery, 110 Medical Science E, University of California, Irvine, CA 92697 5320, USA
    Hear Res 277:61-6. 2011
    ..the low-rate stimulus reduced cortical N100 potentials while increasing the spontaneous alpha power in the auditory cortex. These results are consistent with previous neurophysiological studies employing subjects with and without ..
  74. pmc Single-trial speech suppression of auditory cortex activity in humans
    Adeen Flinker
    Helen Wills Neuroscience Institute and Department of Psychology, University of California, Berkeley, California 94720, USA
    J Neurosci 30:16643-50. 2010
    The human auditory cortex is engaged in monitoring the speech of interlocutors as well as self-generated speech...
  75. ncbi Human cortical activity during streaming without spectral cues suggests a general neural substrate for auditory stream segregation
    Alexander Gutschalk
    Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    J Neurosci 27:13074-81. 2007
    ..We hypothesize that feature-specific forward suppression subserves streaming based on diverse perceptual cues and results in explicit neural representations for auditory streams within auditory cortex.
  76. pmc Recovery of functional and structural age-related changes in the rat primary auditory cortex with operant training
    Etienne de Villers-Sidani
    W M Keck Center for Integrative Neuroscience, Coleman Laboratory, Department of Otolaryngology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 107:13900-5. 2010
    ..We describe here more than 20 age-related cortical processing deficits in the primary auditory cortex of aging versus young rats that appear to be strongly contributed to by altered cortical inhibition...
  77. pmc Multiple mechanisms shape selectivity for FM sweep rate and direction in the pallid bat inferior colliculus and auditory cortex
    Zoltan M Fuzessery
    Department 3166, Zoology and Physiology, University of Wyoming, 1000 E University Ave, Laramie, WY 82071, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 197:615-23. 2011
    The inferior colliculus and auditory cortex of the pallid bat contain a large percentage of neurons that are highly selective for the direction and rate of the downward frequency modulated (FM) sweep of the bat's echolocation pulse...
  78. ncbi Musical training enhances automatic encoding of melodic contour and interval structure
    Takako Fujioka
    The Rotman Research Institute, Baycrest Centre for Geriatric Care
    J Cogn Neurosci 16:1010-21. 2004
    ..demonstrated that people with no formal music education process both contour and interval information in the auditory cortex automatically...
  79. ncbi Bilateral speech comprehension reflects differential sensitivity to spectral and temporal features
    Jonas Obleser
    Max Planck Institute for Human Cognitive and Brain Sciences, 04103 Leipzig, Germany
    J Neurosci 28:8116-23. 2008
    ..Applying direct manipulations to the speech signal rather than to low-level surrogates, the results lend plausibility to the notion of complementary roles for the left and right superior temporal sulci in comprehending the speech signal...
  80. ncbi Cortical discrimination of complex natural stimuli: can single neurons match behavior?
    Le Wang
    Hearing Research Center, Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA
    J Neurosci 27:582-9. 2007
    ..Specifically, we investigate whether neurons in field L, the homolog of primary auditory cortex, can match behavioral performance in the discrimination of conspecific songs...
  81. pmc Laminar and columnar auditory cortex in avian brain
    Yuan Wang
    Department of Neurosciences, School of Medicine, University of California San Diego, La Jolla, CA 92093 0608, USA
    Proc Natl Acad Sci U S A 107:12676-81. 2010
    ..placed into individual layers of the telencephalon within the cortical region that is similar to mammalian auditory cortex. Distribution of anterograde and retrograde transportable markers revealed extensive interconnections across ..
  82. pmc Effect of the environment on the dendritic morphology of the rat auditory cortex
    Mitali Bose
    Laboratory of Cell and Synaptic Physiology, School for Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, Texas, USA
    Synapse 64:97-110. 2010
    ..to identify morphological correlates of environment-induced changes at excitatory synapses of the primary auditory cortex (A1)...
  83. pmc Spatial profile and differential recruitment of GABAB modulate oscillatory activity in auditory cortex
    Anne Marie M Oswald
    Center for Neural Science and Courant Institute of Mathematical Sciences, New York University, New York, NY 10003, USA
    J Neurosci 29:10321-34. 2009
    ..In many cortices, including auditory cortex (ACx), interactions between excitatory and inhibitory neurons generate synchronous network gamma oscillations ..
  84. doi Functional organization and population dynamics in the mouse primary auditory cortex
    Gideon Rothschild
    Department of Neurobiology, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel
    Nat Neurosci 13:353-60. 2010
    ..However, the functional organization and dynamics of local populations in the auditory cortex have remained largely unknown...
  85. pmc Pitch processing sites in the human auditory brain
    Deborah A Hall
    MRC Institute of Hearing Research, University Park, Nottingham, UK
    Cereb Cortex 19:576-85. 2009
    Lateral Heschl's gyrus (HG), a subdivision of the human auditory cortex, is commonly believed to represent a general "pitch center," responding selectively to the pitch of sounds, irrespective of their spectral characteristics...
  86. ncbi Structural brain alterations following 5 days of intervention: dynamic aspects of neuroplasticity
    A May
    Department of Systems Neuroscience, University of Hamburg, Martinist 52, 20246 Hamburg, Germany
    Cereb Cortex 17:205-10. 2007
    ..delivered to the superior temporal cortex causes macroscopic cortical changes in gray matter (GM) in the auditory cortex as early as within 5 days of continuous intervention...
  87. ncbi Distinct time scales in cortical discrimination of natural sounds in songbirds
    Rajiv Narayan
    Hearing Research Center, Department of Biomedical Engineering, Center of BioDynamics, Program in mathematical and Computational Neuroscience, Boston University, Boston, MA 02215, USA
    J Neurophysiol 96:252-8. 2006
    ..However, relatively little is known about discrimination of sounds by auditory cortical neurons. Auditory cortex plays a particularly important role in the discrimination of complex sounds, e.g., vocal communication sounds...
  88. ncbi Auditory stream segregation relying on timbre involves left auditory cortex
    Susann Deike
    Leibniz Institute for Neurobiology, Brenneckestr 6, 39118 Magdeburg, Germany
    Neuroreport 15:1511-4. 2004
    ..We examined human auditory cortex activity with low noise fMRI in a stream segregation experiment relying on timbre differences of alternating ..
  89. ncbi Spectral-temporal receptive fields of nonlinear auditory neurons obtained using natural sounds
    F E Theunissen
    Department of Psychology, University of California, Berkeley, California 94720 1650, USA
    J Neurosci 20:2315-31. 2000
    ....
  90. pmc Columnar connectivity and laminar processing in cat primary auditory cortex
    Craig A Atencio
    Berkeley Bioengineering Graduate Group, University of California, Berkeley, California, United States of America
    PLoS ONE 5:e9521. 2010
    Radial intra- and interlaminar connections form a basic microcircuit in primary auditory cortex (AI) that extracts acoustic information and distributes it to cortical and subcortical networks...
  91. pmc Linking the response properties of cells in auditory cortex with network architecture: cotuning versus lateral inhibition
    Jaime de la Rocha
    Center for Neural Science, New York University, New York, New York 10003, USA
    J Neurosci 28:9151-63. 2008
    The frequency-intensity receptive fields (RF) of neurons in primary auditory cortex (AI) are heterogeneous. Some neurons have V-shaped RFs, whereas others have enclosed ovoid RFs...
  92. ncbi Hemispheric asymmetry for spectral and temporal processing in the human antero-lateral auditory belt cortex
    Marc Schönwiesner
    Faculty of Biosciences, University of Leipzig, Germany
    Eur J Neurosci 22:1521-8. 2005
    ..The findings indicate that asymmetrical processing of complex sounds in the cerebral hemispheres does not depend on semantic, but rather on acoustic stimulus characteristics...
  93. ncbi Functional specificity in the right human auditory cortex for perceiving pitch direction
    I S Johnsrude
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
    Brain 123:155-63. 2000
    ..These findings support a specialization of function linked to right auditory cortical areas for the processing of pitch direction, and specifically suggest a dissociation between simple sensory discrimination and higher order perception...
  94. ncbi Modulation of the auditory cortex during speech: an MEG study
    John F Houde
    Center for Integrative Neuroscience, University of California, San Francisco 94143, USA
    J Cogn Neurosci 14:1125-38. 2002
    ..These data suggest that during speech production, the auditory cortex (1) attenuates its sensitivity and (2) modulates its activity as a function of the expected acoustic feedback.
  95. pmc The role of auditory cortex in the formation of auditory streams
    Christophe Micheyl
    Department of Psychology, University of Minnesota, MN, USA
    Hear Res 229:116-31. 2007
    ..findings concerning the possible neural mechanisms behind this perceptual phenomenon at the level of the auditory cortex. The first part is devoted to intra-cortical recordings, which provide insight into the neural "..
  96. ncbi Functional integration across brain regions improves speech perception under adverse listening conditions
    Jonas Obleser
    Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, United Kingdom
    J Neurosci 27:2283-9. 2007
    ..These results demonstrate that increasing functional connectivity between high-order cortical areas, remote from the auditory cortex, facilitates speech comprehension when the clarity of speech is reduced.
  97. pmc Functional imaging reveals numerous fields in the monkey auditory cortex
    Christopher I Petkov
    Max Planck Institute for Biological Cybernetics, Tubingen, Germany
    PLoS Biol 4:e215. 2006
    Anatomical studies propose that the primate auditory cortex contains more fields than have actually been functionally confirmed or described...
  98. ncbi Structural and functional asymmetry of lateral Heschl's gyrus reflects pitch perception preference
    Peter Schneider
    Department of Neurology, University Hospital Heidelberg, INF 400, D 69120 Heidelberg, Germany
    Nat Neurosci 8:1241-7. 2005
    ..Our data link relative hemispheric lateralization with perceptual stimulus properties, whereas the absolute size of the Heschl's gyrus depends on musical aptitude...
  99. ncbi The role of predictive models in the formation of auditory streams
    S L Denham
    Centre for Theoretical and Computational Neuroscience, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK
    J Physiol Paris 100:154-70. 2006
    ..We present new computational modelling results which replicate responses in primary auditory cortex [Fishman, Y.I., Arezzo, J.C., Steinschneider, M., 2004...
  100. pmc Cooperative nonlinearities in auditory cortical neurons
    Craig A Atencio
    University of California, San Francisco University of California, Berkeley Bioengineering Graduate Group, University of California, San Francisco, San Francisco, CA 94143, USA
    Neuron 58:956-66. 2008
    ..unclear which features of the acoustic environment are specifically represented by neurons in the primary auditory cortex (AI)...
  101. ncbi Enhancement of neuroplastic P2 and N1c auditory evoked potentials in musicians
    Antoine Shahin
    Unit of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    J Neurosci 23:5545-52. 2003
    ..N1c components of the auditory evoked potential (AEP) have been shown to be sensitive to remodeling of the auditory cortex by training at pitch discrimination in nonmusician subjects...

Research Grants97

  1. Brain changes in tinnitus
    JOSEF RAUSCHECKER; Fiscal Year: 2009
    ..touches on the face (which are normally processed in an adjacent area of somatosensory cortex), the areas of auditory cortex affected by hearing loss start responding to hearing-loss edge frequencies...
  2. Brain changes in tinnitus
    Josef P Rauschecker; Fiscal Year: 2010
    ..touches on the face (which are normally processed in an adjacent area of somatosensory cortex), the areas of auditory cortex affected by hearing loss start responding to hearing-loss edge frequencies...
  3. The Impact of Frequency Compression on Cortical Evoked Potentials and Perception
    Benjamin J Kirby; Fiscal Year: 2012
    ..been established that cortical auditory evoked potentials (CAEPs), objective recordings of activity in the auditory cortex, may serve as an alternative to parental report for fitting hearing aids...
  4. Role of serotonin in auditory cortex regulation following early-onset sensorineur
    GREGORY BASURA; Fiscal Year: 2009
    ..Hearing impairments during early postnatal development produce significant changes in the human auditory cortex that may permanently diminish auditory perceptual skills and compromise language acquisition (Psarommatis et ..
  5. Plasticity of Auditory Cortical Circuits in Schizophrenia
    Robert Sweet; Fiscal Year: 2009
    ..Tone discrimination depends on excitatory connections amongst networks of layer 3 pyramidal cells in primary auditory cortex (AI)...
  6. Plasticity of Auditory Cortical Circuits in Schizophrenia
    Robert A Sweet; Fiscal Year: 2010
    ..Tone discrimination depends on excitatory connections amongst networks of layer 3 pyramidal cells in primary auditory cortex (AI)...
  7. AUDITORY TECTO-THALAMIC PATHWAYS: INFORMATION PROCESSING
    Jeffrey Wenstrup; Fiscal Year: 1991
    ..by multiple pathways projecting from the inferior colliculus to the medial geniculate body, and then to the auditory cortex. The long term goal of this research is to evaluate information processing within these auditory pathways...
  8. FUNCTIONAL ORGANIZATION OF PRIMARY AUDITORY CORTEX
    Christoph E Schreiner; Fiscal Year: 2011
    ..We attempt to explore the normal function of the auditory cortex for processing complex signals and signals in different types of background noise in order to ascertain the ..
  9. Parsing the schizophrenia-bipolar spectrum: an MEG based schizoaffective endophen
    Martin Reite; Fiscal Year: 2009
    ..status of GABAergic interneuronal activity regulating firing patterns of layer 3 pyramidal cells in auditory cortex of Heschl's gyrus...
  10. Parsing the schizophrenia-bipolar spectrum: an MEG based schizoaffective endophen
    Martin Reite; Fiscal Year: 2010
    ..status of GABAergic interneuronal activity regulating firing patterns of layer 3 pyramidal cells in auditory cortex of Heschl's gyrus...
  11. Adaptation to Unilateral Hearing Loss in Humans: Cortical and Perceptual Effects
    Peter Gordon; Fiscal Year: 2007
    ..provided by applicant): The goal of this project is to increase understanding of adaptation in human auditory cortex after peripheral hearing loss in adults...
  12. Integration of ascending and descending input to auditory cortex
    Matthew I Banks; Fiscal Year: 2010
    ..Here, we propose to investigate the cellular and circuit mechanisms of this integrative process in auditory cortex and its modulation by general anesthetics...
  13. Integration of ascending and descending input to auditory cortex
    Matthew Banks; Fiscal Year: 2009
    ..Here, we propose to investigate the cellular and circuit mechanisms of this integrative process in auditory cortex and its modulation by general anesthetics...
  14. Cortical Sensitivity to Acoustic Cues for Sound Location
    EWAN MACPHERSON; Fiscal Year: 2006
    ..Sound localization is a fundamental task of the auditory system, and in higher mammals, requires an intact auditory cortex. Many cortical neurons respond over broad regions of space and vary the rate and temporal pattern of their ..
  15. Cortical Sensitivity to Acoustic Cues for Sound Location
    EWAN MACPHERSON; Fiscal Year: 2004
    Sound localization is a fundamental task of the auditory system, and in higher mammals, requires an intact auditory cortex. Many cortical neurons respond over broad regions of space and vary the rate and temporal pattern of their ..
  16. HUMAN AUDITORY CORTEX PHYSIOLOGY
    Matthew Howard; Fiscal Year: 2000
    The unifying focus of the proposed research is the study of human auditory cortex. The two specific areas of investigation will be: l) Cellular electrophysiology of human auditory cortex, 2) Feasibility studies of an auditory cortex ..
  17. HUMAN AUDITORY CORTEX PHYSIOLOGY
    Matthew Howard; Fiscal Year: 1999
    The unifying focus of the proposed research is the study of human auditory cortex. The two specific areas of investigation will be: l) Cellular electrophysiology of human auditory cortex, 2) Feasibility studies of an auditory cortex ..
  18. Cortical Sensitivity to Acoustic Cues for Sound Location
    EWAN MACPHERSON; Fiscal Year: 2005
    Sound localization is a fundamental task of the auditory system, and in higher mammals, requires an intact auditory cortex. Many cortical neurons respond over broad regions of space and vary the rate and temporal pattern of their ..
  19. Feature selectivity of auditory thalamus
    Edward Bartlett; Fiscal Year: 2003
    ..arise from the MGB representations, given the comparatively large body of knowledge regarding responses of auditory cortex neurons to auditory stimuli...
  20. Feature selectivity of auditory thalamus
    Edward Bartlett; Fiscal Year: 2004
    ..arise from the MGB representations, given the comparatively large body of knowledge regarding responses of auditory cortex neurons to auditory stimuli...
  21. Feature selectivity of auditory thalamus
    Edward Bartlett; Fiscal Year: 2005
    ..arise from the MGB representations, given the comparatively large body of knowledge regarding responses of auditory cortex neurons to auditory stimuli...
  22. GABAergic Circuits in Auditory Cortex
    Matthew Banks; Fiscal Year: 2003
    ..In this proposal, we seek to understand how GABAergic cells control the timing of action potentials in auditory cortex (ACx)...
  23. GABAergic Circuits in Auditory Cortex
    Matthew Banks; Fiscal Year: 2006
    ..In this proposal, we seek to understand how GABAergic cells control the timing of action potentials in auditory cortex (ACx)...
  24. Anatomical analysis of cortical projections to the auditory midbrain
    KYLE TOKUICHI NAKAMOTO; Fiscal Year: 2010
    ..The auditory cortex is the source of massive descending projections that are considered to play a role in a wide range of ..
  25. Technological Development Towards a Cortical Prosthesis
    Patrick Rousche; Fiscal Year: 2004
    ..Preliminary evidence suggests that direct electrical stimulation of the human auditory cortex can induce auditory perceptions...
  26. Technological Development Towards a Cortical Prosthesis
    Patrick Rousche; Fiscal Year: 2005
    ..Preliminary evidence suggests that direct electrical stimulation of the human auditory cortex can induce auditory perceptions...
  27. Cortical Electrical Suppression of Noise-Induced Tinnitus
    Jinsheng Zhang; Fiscal Year: 2009
    ..Among numerous management strategies being sought, auditory cortex electrical stimulation (ACES) has recently been used clinically to suppress tinnitus...
  28. Population code for sound localization in auditory cortex
    Khaleel A Razak; Fiscal Year: 2010
    ..The auditory cortex is involved in sound localization behavior...
  29. ROLE OF VISUAL INPUTS IN THALAMIC & CORTICAL DEVELOPMENT
    Mriganka Sur; Fiscal Year: 1992
    ..The MGN with retinal input retains its projections to auditory cortex. We have shown that retinal input to the MGN in "rewired" animals arises from small retinal ganglion cells ..
  30. Population code for sound localization in auditory cortex
    KHALEEL RAZAK; Fiscal Year: 2009
    ..The auditory cortex is involved in sound localization behavior...
  31. Cortical Electrical Suppression of Noise-Induced Tinnitus
    Jinsheng Zhang; Fiscal Year: 2010
    ..Among numerous management strategies being sought, auditory cortex electrical stimulation (ACES) has recently been used clinically to suppress tinnitus...
  32. Cortical Electrical Suppression of Noise-Induced Tinnitus
    Jinsheng Zhang; Fiscal Year: 2009
    ..Among numerous management strategies being sought, auditory cortex electrical stimulation (ACES) has recently been used clinically to suppress tinnitus...
  33. Neural mechanisms of auditory feedback during speech
    Srikantan Nagarajan; Fiscal Year: 2005
    ..Recent studies have shown that in auditory cortex and other areas in the superior temporal plane, speaking causes "speaking-induced suppression" (SIS): ..
  34. Neural mechanisms of auditory feedback during speech
    Srikantan Nagarajan; Fiscal Year: 2004
    ..Recent studies have shown that in auditory cortex and other areas in the superior temporal plane, speaking causes "speaking-induced suppression" (SIS): ..
  35. Neural mechanisms of auditory feedback during speech
    Srikantan Nagarajan; Fiscal Year: 2006
    ..Recent studies have shown that in auditory cortex and other areas in the superior temporal plane, speaking causes "speaking-induced suppression" (SIS): ..
  36. Neural mechanisms of auditory feedback during speech
    Srikantan Nagarajan; Fiscal Year: 2007
    ..Recent studies have shown that in auditory cortex and other areas in the superior temporal plane, speaking causes "speaking-induced suppression" (SIS): ..
  37. Influences of developmental hearing loss on auditory perception and neural coding
    MERRI ROSEN; Fiscal Year: 2007
    ..is that mild to moderate conductive HL during development permanently disrupts coding properties in the auditory cortex, leading to measurable deficits in perceptual performance. There are three related experimental aims...
  38. FUNCTIONAL ORGANIZATION--NONPRIMARY AUDITORY CORTEX
    JOSEF RAUSCHECKER; Fiscal Year: 2000
    ..Much less is known about multiple representations in the auditory cortex. This is surprising because a thorough knowledge of nonprimary auditory cortex is undoubtedly necessary for ..
  39. FUNCTIONAL ORGANIZATION--NONPRIMARY AUDITORY CORTEX
    JOSEF RAUSCHECKER; Fiscal Year: 2001
    ..Much less is known about multiple representations in the auditory cortex. This is surprising because a thorough knowledge of nonprimary auditory cortex is undoubtedly necessary for ..
  40. FUNCTIONAL ORGANIZATION--NONPRIMARY AUDITORY CORTEX
    JOSEF RAUSCHECKER; Fiscal Year: 1999
    ..Much less is known about multiple representations in the auditory cortex. This is surprising because a thorough knowledge of nonprimary auditory cortex is undoubtedly necessary for ..
  41. FUNCTIONAL ORGANIZATION--NONPRIMARY AUDITORY CORTEX
    JOSEF RAUSCHECKER; Fiscal Year: 1999
    ..Much less is known about multiple representations in the auditory cortex. This is surprising because a thorough knowledge of nonprimary auditory cortex is undoubtedly necessary for ..
  42. ACTIVITY OF AI NEURONS IN LOCALIZING SOUNDS
    Gregg Recanzone; Fiscal Year: 2000
    ..An apparent paradox exists, where lesions of the auditory cortex result in profound sound localization deficits, but the spatial selectivity of most cells in auditory cortex ..
  43. Functional organization of auditory corticothalamic projection systems
    Daniel Llano; Fiscal Year: 2006
    ..Summary: The objective of the proposed studies is to understand the functional relationships between the auditory cortex and thalamus, and ultimately to uncover the neural substrates for auditory cognition...
  44. ACTIVITY OF AI NEURONS IN LOCALIZING SOUNDS
    Gregg Recanzone; Fiscal Year: 1999
    ..An apparent paradox exists, where lesions of the auditory cortex result in profound sound localization deficits, but the spatial selectivity of most cells in auditory cortex ..
  45. Functional organization of auditory corticothalamic projection systems
    Daniel Llano; Fiscal Year: 2007
    ..Summary: The objective of the proposed studies is to understand the functional relationships between the auditory cortex and thalamus, and ultimately to uncover the neural substrates for auditory cognition...
  46. SPEECH SOUND PROCESSING IN AUDITORY CORTEX
    Mitchell Steinschneider; Fiscal Year: 1990
    ..of this project is to employ electrophysiological responses to human speech sounds within monkey primate auditory cortex (AI) as a model of neural mechanisms that underlie cortical processing of acoustic and phonetic features of ..
  47. Effects of Spectral Context on Responses in Auditory Cortex
    DENNIS BARBOUR; Fiscal Year: 2009
    ..and communication sound encoding in the mammalian auditory system by evaluating how neurons in primate auditory cortex integrate sound energy over a wide range of frequencies...
  48. Effects of Spectral Context on Responses in Auditory Cortex
    DENNIS BARBOUR; Fiscal Year: 2009
    ..and communication sound encoding in the mammalian auditory system by evaluating how neurons in primate auditory cortex integrate sound energy over a wide range of frequencies...
  49. PARALLEL AUDITORY PATHWAYS IN THE BRAIN STEM
    Ellen Covey; Fiscal Year: 2006
    ..multiple auditory centers in the lower brainstem, from non-ascending auditory inputs from the opposite IC and auditory cortex and from motor-related structures...
  50. PARALLEL AUDITORY PATHWAYS IN THE BRAIN STEM
    JOHN CASSEDAY; Fiscal Year: 2003
    ..multiple auditory centers in the lower brainstem, from non-ascending auditory inputs from the opposite IC and auditory cortex and from motor-related structures...
  51. PARALLEL AUDITORY PATHWAYS IN THE BRAIN STEM
    JOHN CASSEDAY; Fiscal Year: 2004
    ..multiple auditory centers in the lower brainstem, from non-ascending auditory inputs from the opposite IC and auditory cortex and from motor-related structures...
  52. PARALLEL AUDITORY PATHWAYS IN THE BRAIN STEM
    JOHN CASSEDAY; Fiscal Year: 2005
    ..multiple auditory centers in the lower brainstem, from non-ascending auditory inputs from the opposite IC and auditory cortex and from motor-related structures...
  53. PARALLEL AUDITORY PATHWAYS IN THE BRAIN STEM
    JOHN CASSEDAY; Fiscal Year: 2002
    ..multiple auditory centers in the lower brainstem, from non-ascending auditory inputs from the opposite IC and auditory cortex and from motor-related structures...
  54. Speech sound processing within human auditory cortex during self-vocalization
    JEREMY GREENLEE; Fiscal Year: 2009
    ..Despite the importance of this neural system, little is known about how auditory cortex functions when humans vocalize...
  55. STRUCTURE OF PRIMARY AUDITORY CORTEX
    JEFFERY WINER; Fiscal Year: 2007
    ..experiments will chart the connections between the inferior colliculus (IC), medial geniculate body (MGB) and auditory cortex (AC), three structures essential for normal hearing...
  56. STRUCTURE OF PRIMARY AUDITORY CORTEX
    JEFFERY WINER; Fiscal Year: 2006
    ..experiments will chart the connections between the inferior colliculus (IC), medial geniculate body (MGB) and auditory cortex (AC), three structures essential for normal hearing...
  57. EARLY CORTICAL PROCESSING IN SCHIZOPHRENIA
    Daniel Javitt; Fiscal Year: 1993
    ..stimulus delivery, and indexes the automatic detection of stimulus deviance by neural structures within auditory cortex or surrounding regions of the superior temporal plane...
  58. Speech sound processing within human auditory cortex during self-vocalization
    JEREMY GREENLEE; Fiscal Year: 2010
    ..Despite the importance of this neural system, little is known about how auditory cortex functions when humans vocalize...
  59. GABAergic Circuits in Auditory Cortex
    Matthew Banks; Fiscal Year: 2007
    ..In this proposal, we seek to understand how GABAergic cells control the timing of action potentials in auditory cortex (ACx)...
  60. STRUCTURE OF PRIMARY AUDITORY CORTEX
    JEFFERY WINER; Fiscal Year: 1990
    This is a proposal to study the structure, connections, and neurochemical organization of the primary auditory cortex (AI), medial geniculate body, and inferior colliculus in several species...
  61. STRUCTURE OF PRIMARY AUDITORY CORTEX
    JEFFERY WINER; Fiscal Year: 2000
    This is a proposal to study the structure, connections, and neurochemical organization of the primary auditory cortex (AI), medial geniculate body, and inferior colliculus in several species...
  62. STRUCTURE OF PRIMARY AUDITORY CORTEX
    JEFFERY WINER; Fiscal Year: 1999
    This is a proposal to study the structure, connections, and neurochemical organization of the primary auditory cortex (AI), medial geniculate body, and inferior colliculus in several species...
  63. Optogenetic analysis of circuits for vocal recognition
    Richard Mooney; Fiscal Year: 2009
    ..Most of these conditions involve damage or dysfunction in the auditory cortex, indicating that this structure plays an essential role in vocal perception...
  64. CRCNS: Dynamics of the auditory cortical column
    Gyorgy Buzsaki; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): The auditory cortex is a critical structure for processing of sound information in mammals...
  65. STRUCTURE OF PRIMARY AUDITORY CORTEX
    JEFFERY WINER; Fiscal Year: 2002
    DESCRIPTION: (Adapted from applicant's abstract): A series of studies are proposed that will analyze how auditory cortex, the medial geniculate body, and the inferior colliculus are interrelated anatomically...
  66. STRUCTURE OF PRIMARY AUDITORY CORTEX
    JEFFERY WINER; Fiscal Year: 2003
    DESCRIPTION: (Adapted from applicant's abstract): A series of studies are proposed that will analyze how auditory cortex, the medial geniculate body, and the inferior colliculus are interrelated anatomically...
  67. STRUCTURE OF PRIMARY AUDITORY CORTEX
    JEFFERY WINER; Fiscal Year: 2004
    DESCRIPTION: (Adapted from applicant's abstract): A series of studies are proposed that will analyze how auditory cortex, the medial geniculate body, and the inferior colliculus are interrelated anatomically...
  68. STRUCTURE OF PRIMARY AUDITORY CORTEX
    JEFFERY WINER; Fiscal Year: 2005
    DESCRIPTION: (Adapted from applicant's abstract): A series of studies are proposed that will analyze how auditory cortex, the medial geniculate body, and the inferior colliculus are interrelated anatomically...
  69. Amygdalar modulation of processing in auditory cortex
    DIANA COOMES PETERSON; Fiscal Year: 2010
    ..processes the emotional significance of sensory stimuli) influences the processing of auditory information in auditory cortex (AC). Individuals/animals pay more attention to significant versus insignificant stimuli...
  70. STRUCTURE OF PRIMARY AUDITORY CORTEX
    JEFFERY WINER; Fiscal Year: 2001
    DESCRIPTION: (Adapted from applicant's abstract): A series of studies are proposed that will analyze how auditory cortex, the medial geniculate body, and the inferior colliculus are interrelated anatomically...
  71. CRCNS: Dynamics of the auditory cortical column
    Gyorgy Buzsaki; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): The auditory cortex is a critical structure for processing of sound information in mammals...
  72. Single-unit response to AM sound in the auditory cortex.
    Mamiko Niwa; Fiscal Year: 2009
    ..We will record single-units responses in the primary auditory cortex (A1) and the middle-lateral field of the auditory cortex (ML) of non-human subjects while they actively ..
  73. CRCNS: Dynamics of the auditory cortical column
    Kenneth Harris; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): The auditory cortex is a critical structure for processing of sound information in mammals...
  74. Single-unit response to AM sound in the auditory cortex.
    Mamiko Niwa; Fiscal Year: 2007
    ..We will record single-units responses in the primary auditory cortex (A1) and the middle-lateral field of the auditory cortex (ML) of non-human subjects while they actively ..
  75. Targeted Neural Plasticity for the Treatment of Tinnitus
    Richard S Tyler; Fiscal Year: 2012
    ..The tinnitus field generally accepts that elevated synchronous spontaneous activity in the auditory cortex may account for the tinnitus percept that arises following hearing loss...
  76. CORTICAL REPRESENTATION OF AUDITORY SPACE
    JOHN MIDDLEBROOKS; Fiscal Year: 1990
    Clinical and animal studies indicate that lesions of the auditory cortex can result in deficits in the ability to localize a sound...
  77. CORTICAL REPRESENTATION OF AUDITORY SPACE
    JOHN MIDDLEBROOKS; Fiscal Year: 1991
    Clinical and animal studies indicate that lesions of the auditory cortex can result in deficits in the ability to localize a sound...
  78. Functional neuroanatomy of auditory object perception
    Amber Leaver; Fiscal Year: 2009
    ..in visual neuroscience, leaving significant gaps in our understanding of functional organization of human auditory cortex. The work proposed here will answer important questions regarding representation of auditory objects (i.e...
  79. Auditory Cortical Processing of Communication Sounds
    Kamal Sen; Fiscal Year: 2007
    unreadable] DESCRIPTION (provided by applicant): Auditory cortex plays an important role in the processing of complex sounds e.g., vocal communication sounds and human speech...
  80. Auditory Cortical Processing of Communication Sounds
    Kamal Sen; Fiscal Year: 2009
    b>Auditory cortex plays an important role in the processing of complex sounds e.g., vocal communication sounds and human speech...
  81. Targeted Neural Plasticity for the Treatment of Tinnitus
    NAVZER ENGINEER; Fiscal Year: 2009
    ..Recent studies suggest that pathological reorganization of frequency mapping in the auditory cortex is a major contributor to the symptoms of tinnitus in many patients...
  82. Targeted Neural Plasticity for the Treatment of Tinnitus
    NAVZER ENGINEER; Fiscal Year: 2009
    ..Recent studies suggest that pathological reorganization of frequency mapping in the auditory cortex is a major contributor to the symptoms of tinnitus in many patients...
  83. CEREBRAL ORGANIZATION FOLLOWING COCHLEAR IMPLANT
    STEPHEN LOMBER; Fiscal Year: 2003
    Following implantation of a cochlear prosthetic, auditory cortex exhibits a remarkable plasticity in its ability to establish auditory signal processing after a period of deprivation...
  84. Auditory Cortical Processing of Communication Sounds
    Kamal Sen; Fiscal Year: 2006
    unreadable] DESCRIPTION (provided by applicant): Auditory cortex plays an important role in the processing of complex sounds e.g., vocal communication sounds and human speech...
  85. Age related effects on macaque auditory cortex
    Gregg Recanzone; Fiscal Year: 2006
    ..is due in large part to the lack of an effective animal model that (1) shares many organizational features of auditory cortex with humans, (2) has a reasonably long life span such that age-related hearing deficits progress over the ..
  86. CEREBRAL ORGANIZATION FOLLOWING COCHLEAR IMPLANT
    STEPHEN LOMBER; Fiscal Year: 2004
    Following implantation of a cochlear prosthetic, auditory cortex exhibits a remarkable plasticity in its ability to establish auditory signal processing after a period of deprivation...
  87. Auditory Cortical Processing of Communication Sounds
    KAMAL K SEN; Fiscal Year: 2010
    b>Auditory cortex plays an important role in the processing of complex sounds e.g., vocal communication sounds and human speech...
  88. Targeted Neural Plasticity for the Treatment of Tinnitus
    NAVZER ENGINEER; Fiscal Year: 2009
    ..Recent studies suggest that pathological reorganization of frequency mapping in the auditory cortex is a major contributor to the symptoms of tinnitus in many patients...