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Publications
Increased auditory cortical representation in musiciansC Pantev
Biomagnetism Center, Institute of Experimental Audiology, University of Munster, Germany
Nature 392:811-4. 1998....
Dichotomy of functional organization in the mouse auditory cortexSharba Bandyopadhyay
Department of Biology, University of Maryland, College Park, Maryland, USA
Nat Neurosci 13:361-8. 2010..The gradient of frequency selectivity (tonotopy) is the dominant organizational feature in the primary auditory cortex, whereas other feature-based organizations are less well established...
Sensitivity of newborn auditory cortex to the temporal structure of soundsSilke Telkemeyer
Berlin NeuroImaging Center, Charite University Medicine, 10117 Berlin, Germany
J Neurosci 29:14726-33. 2009..That is, the newborn auditory cortex is sensitive to the temporal structure of the auditory input and shows an emerging tendency for functional ..
Correlating stimulus-specific adaptation of cortical neurons and local field potentials in the awake ratWolfger von der Behrens
Institute for Cell Biology and Neuroscience, Department of Biological Sciences, Goethe University, Frankfurt am Main, Germany
J Neurosci 29:13837-49. 2009..Stimulus-specific adaptation (SSA) of single neurons in the auditory cortex has been proposed to be the cellular substrate of MMN (Nelken and Ulanovsky, 2007)...
Spectral interactions, but no mismatch negativity, in auditory cortex of anesthetized ratRonit Lazar
Department of Neurobiology and Behavior, University of California, Irvine, 2205 McGaugh Hall, Irvine, CA 92697, USA
Hear Res 181:51-6. 2003We used an 'oddball' stimulation paradigm to evoke epidural, event-related potentials over auditory cortex in urethane/xylazine-anesthetized rats, in order to study the neural mechanisms underlying the mismatch negativity (MMN)...
The processing of temporal pitch and melody information in auditory cortexRoy D Patterson
Centre for the Neural Basis of Hearing, Physiology Department, University of Cambridge, Downing Street, Cambridge, United Kingdom
Neuron 36:767-76. 2002..The results support the view that there is hierarchy of pitch processing in which the center of activity moves anterolaterally away from primary auditory cortex as the processing of melodic sounds proceeds.
Maps and streams in the auditory cortex: nonhuman primates illuminate human speech processingJosef P Rauschecker
Laboratory of Integrative Neuroscience and Cognition, Georgetown University Medical Center, Washington, DC, USA
Nat Neurosci 12:718-24. 2009..Chief among these are physiological and anatomical studies showing that primate auditory cortex, across species, shows patterns of hierarchical structure, topographic mapping and streams of functional ..
How the brain separates soundsRobert P Carlyon
MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 2EF, UK
Trends Cogn Sci 8:465-71. 2004..Listeners' sensitivity to streaming cues can be captured in the responses of neurons in the primary auditory cortex, and in EEG wave components with a short latency (< 200ms)...
Stimulus-specific adaptation in the auditory thalamus of the anesthetized ratFlora M Antunes
Auditory Neurophysiology Unit, Laboratory for the Neurobiology of Hearing, Institute of Neuroscience of Castilla y Leon, University of Salamanca, Salamanca, Spain
PLoS ONE 5:e14071. 2010..Previous studies have demonstrated that neurons in the auditory cortex and inferior colliculus show SSA...
Processing of low-probability sounds by cortical neuronsNachum Ulanovsky
Department of Physiology, Hebrew University, Hadassah Medical School, Box 12272, Jerusalem 91120, Israel
Nat Neurosci 6:391-8. 2003..We report here that neurons in cat primary auditory cortex (A1) responded more strongly to a rarely presented sound than to the same sound when it was common...
Sensory-motor interaction in the primate auditory cortex during self-initiated vocalizationsSteven J Eliades
Laboratory of Auditory Neurophysiology, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
J Neurophysiol 89:2194-207. 2003Little is known about sensory-motor interaction in the auditory cortex of primates at the level of single neurons and its role in supporting vocal communication...
Spectral and temporal processing in human auditory cortexR J Zatorre
Montreal Neurological Institute, McGill University, 3801 University St, Montreal, QC H3A 2B4, Canada
Cereb Cortex 11:946-53. 2001We used positron emission tomography to examine the response of human auditory cortex to spectral and temporal variation...
Morphology of Heschl's gyrus reflects enhanced activation in the auditory cortex of musiciansPeter Schneider
Department of Physics, University of Heidelberg, Philosophenweg 12, D 69120 Heidelberg, Germany
Nat Neurosci 5:688-94. 2002Using magnetoencephalography (MEG), we compared the processing of sinusoidal tones in the auditory cortex of 12 non-musicians, 12 professional musicians and 13 amateur musicians...
Tinnitus intensity dependent gamma oscillations of the contralateral auditory cortexElsa van der Loo
Brain Research centre Antwerp for Innovative and Interdisciplinary Neuromodulation BRAI 2 N, University Hospital Antwerp, Antwerp, Belgium
PLoS ONE 4:e7396. 2009..Tinnitus as a phantom phenomenon is related to hyperactivity and reorganization of the auditory cortex. Magnetoencephalography studies demonstrate a correlation between gamma band activity in the contralateral ..
Mechanisms and streams for processing of "what" and "where" in auditory cortexJ P Rauschecker
Georgetown Institute for Cognitive and Computational Sciences, Georgetown University Medical Center, Washington, DC 20007, USA
Proc Natl Acad Sci U S A 97:11800-6. 2000The functional specialization and hierarchical organization of multiple areas in rhesus monkey auditory cortex were examined with various types of complex sounds...
Auditory cortex on the human posterior superior temporal gyrusM A Howard
Department of Surgery Division of Neurosurgery, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
J Comp Neurol 416:79-92. 2000..These physiological findings are in accord with anatomic evidence in humans and in nonhuman primates that the superior temporal cortex contains multiple interconnected auditory areas...
Listening to tailor-made notched music reduces tinnitus loudness and tinnitus-related auditory cortex activityHidehiko Okamoto
Institute for Biomagnetism and Biosignalanalysis, Westfalian Wilhelms University, Malmedyweg 15, Muenster, Germany
Proc Natl Acad Sci U S A 107:1207-10. 2010Maladaptive auditory cortex reorganization may contribute to the generation and maintenance of tinnitus...
Synaptic mechanisms of forward suppression in rat auditory cortexMichael Wehr
Cold Spring Harbor Laboratory, New York 11724, USA
Neuron 47:437-45. 2005In the auditory cortex, brief sounds elicit a powerful suppression of responsiveness that can persist for hundreds of milliseconds...
Multiple time scales of adaptation in auditory cortex neuronsNachum Ulanovsky
Department of Neurobiology, The Alexander Silberman Institute of Life Sciences, Hebrew University, Jerusalem 91904, Israel
J Neurosci 24:10440-53. 2004Neurons in primary auditory cortex (A1) of cats show strong stimulus-specific adaptation (SSA)...
Relationship of imprecise corollary discharge in schizophrenia to auditory hallucinationsTheda H Heinks Maldonado
Department of Neuropsychology, Albert Ludwigs Universitat, Freiburg, Germany
Arch Gen Psychiatry 64:286-96. 2007..Imprecision of the corollary discharge in schizophrenia may contribute to the misperception of inner experiences and thoughts as "voices" or auditory hallucinations...
Temporal and rate representations of time-varying signals in the auditory cortex of awake primatesT Lu
Laboratory of Auditory Neurophysiology, Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 424, Baltimore, Maryland 21205, USA
Nat Neurosci 4:1131-8. 2001..Here we show that there are two largely distinct populations of neurons in the auditory cortex of awake primates: one with stimulus-synchronized discharges that, with a temporal code, explicitly ..
Perceptual learning directs auditory cortical map reorganization through top-down influencesDaniel B Polley
W M Keck Foundation Center for Integrative Neuroscience, Department of Otolaryngology, University of California, San Francisco, California 94143 0732, USA
J Neurosci 26:4970-82. 2006..We tested whether topographic map plasticity in the adult primary auditory cortex and a secondary auditory area, the suprarhinal auditory field, was controlled by the statistics of bottom-up ..
Perceptual organization of tone sequences in the auditory cortex of awake macaquesChristophe Micheyl
Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
Neuron 48:139-48. 2005..formation measured in humans using alternating-tone sequences can be quantitatively accounted for based on single-unit responses recorded in the primary auditory cortex (A1) of awake rhesus monkeys listening to the same sound sequences.
Cortical discrimination of complex natural stimuli: can single neurons match behavior?Le Wang
Hearing Research Center, Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA
J Neurosci 27:582-9. 2007..Specifically, we investigate whether neurons in field L, the homolog of primary auditory cortex, can match behavioral performance in the discrimination of conspecific songs...
Sparse representation of sounds in the unanesthetized auditory cortexTomás Hromádka
Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Cold Spring Harbor, New York, United States of America
PLoS Biol 6:e16. 2008How do neuronal populations in the auditory cortex represent acoustic stimuli? Although sound-evoked neural responses in the anesthetized auditory cortex are mainly transient, recent experiments in the unanesthetized preparation have ..
Columnar connectivity and laminar processing in cat primary auditory cortexCraig A Atencio
Berkeley Bioengineering Graduate Group, University of California, Berkeley, California, United States of America
PLoS ONE 5:e9521. 2010Radial intra- and interlaminar connections form a basic microcircuit in primary auditory cortex (AI) that extracts acoustic information and distributes it to cortical and subcortical networks...
Cross-modal plasticity in specific auditory cortices underlies visual compensations in the deafStephen G Lomber
Centre for Brain and Mind, Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada
Nat Neurosci 13:1421-7. 2010..In the absence of acoustic input, it has been proposed that cross-modal reorganization of deaf auditory cortex may provide the neural substrate mediating compensatory visual function...
Distinct time scales in cortical discrimination of natural sounds in songbirdsRajiv Narayan
Hearing Research Center, Department of Biomedical Engineering, Center of BioDynamics, Program in mathematical and Computational Neuroscience, Boston University, Boston, MA 02215, USA
J Neurophysiol 96:252-8. 2006..However, relatively little is known about discrimination of sounds by auditory cortical neurons. Auditory cortex plays a particularly important role in the discrimination of complex sounds, e.g., vocal communication sounds...
Neural activity in speech-sensitive auditory cortex during silenceM D Hunter
Sheffield Cognition and Neuroimaging Laboratory SCANLab, Academic Clinical Psychiatry, Division of Genomic Medicine, University of Sheffield, Sheffield S5 7JT, United Kingdom
Proc Natl Acad Sci U S A 103:189-94. 2006..heard in the absence of external stimuli implies the existence of endogenous neural activity within the auditory cortex responsible for their perception...
Structural brain alterations following 5 days of intervention: dynamic aspects of neuroplasticityA May
Department of Systems Neuroscience, University of Hamburg, Martinist 52, 20246 Hamburg, Germany
Cereb Cortex 17:205-10. 2007..delivered to the superior temporal cortex causes macroscopic cortical changes in gray matter (GM) in the auditory cortex as early as within 5 days of continuous intervention...
Sound categories are represented as distributed patterns in the human auditory cortexNoel Staeren
Faculty of Psychology and Neuroscience, Department of Cognitive Neuroscience, University of Maastricht, 6200 MD Maastricht, The Netherlands
Curr Biol 19:498-502. 2009....
Laminar and columnar auditory cortex in avian brainYuan Wang
Department of Neurosciences, School of Medicine, University of California San Diego, La Jolla, CA 92093 0608, USA
Proc Natl Acad Sci U S A 107:12676-81. 2010..placed into individual layers of the telencephalon within the cortical region that is similar to mammalian auditory cortex. Distribution of anterograde and retrograde transportable markers revealed extensive interconnections across ..
Pitch processing sites in the human auditory brainDeborah A Hall
MRC Institute of Hearing Research, University Park, Nottingham, UK
Cereb Cortex 19:576-85. 2009Lateral Heschl's gyrus (HG), a subdivision of the human auditory cortex, is commonly believed to represent a general "pitch center," responding selectively to the pitch of sounds, irrespective of their spectral characteristics...
Rapid synaptic depression explains nonlinear modulation of spectro-temporal tuning in primary auditory cortex by natural stimuliStephen V David
Institute for Systems Research, University of Maryland, College Park, Maryland 20742, USA
J Neurosci 29:3374-86. 2009In this study, we explored ways to account more accurately for responses of neurons in primary auditory cortex (A1) to natural sounds...
Effect of the environment on the dendritic morphology of the rat auditory cortexMitali Bose
Laboratory of Cell and Synaptic Physiology, School for Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, Texas, USA
Synapse 64:97-110. 2010..to identify morphological correlates of environment-induced changes at excitatory synapses of the primary auditory cortex (A1)...
Spatial profile and differential recruitment of GABAB modulate oscillatory activity in auditory cortexAnne Marie M Oswald
Center for Neural Science and Courant Institute of Mathematical Sciences, New York University, New York, NY 10003, USA
J Neurosci 29:10321-34. 2009..In many cortices, including auditory cortex (ACx), interactions between excitatory and inhibitory neurons generate synchronous network gamma oscillations ..
Bilateral speech comprehension reflects differential sensitivity to spectral and temporal featuresJonas Obleser
Max Planck Institute for Human Cognitive and Brain Sciences, 04103 Leipzig, Germany
J Neurosci 28:8116-23. 2008..Applying direct manipulations to the speech signal rather than to low-level surrogates, the results lend plausibility to the notion of complementary roles for the left and right superior temporal sulci in comprehending the speech signal...
Functional organization and population dynamics in the mouse primary auditory cortexGideon Rothschild
Department of Neurobiology, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel
Nat Neurosci 13:353-60. 2010..However, the functional organization and dynamics of local populations in the auditory cortex have remained largely unknown...
Linking the response properties of cells in auditory cortex with network architecture: cotuning versus lateral inhibitionJaime de la Rocha
Center for Neural Science, New York University, New York, New York 10003, USA
J Neurosci 28:9151-63. 2008The frequency-intensity receptive fields (RF) of neurons in primary auditory cortex (AI) are heterogeneous. Some neurons have V-shaped RFs, whereas others have enclosed ovoid RFs...
Spectral-temporal receptive fields of nonlinear auditory neurons obtained using natural soundsF E Theunissen
Department of Psychology, University of California, Berkeley, California 94720 1650, USA
J Neurosci 20:2315-31. 2000....
Auditory stream segregation relying on timbre involves left auditory cortexSusann Deike
Leibniz Institute for Neurobiology, Brenneckestr 6, 39118 Magdeburg, Germany
Neuroreport 15:1511-4. 2004..We examined human auditory cortex activity with low noise fMRI in a stream segregation experiment relying on timbre differences of alternating ..
Musical training enhances automatic encoding of melodic contour and interval structureTakako Fujioka
The Rotman Research Institute, Baycrest Centre for Geriatric Care
J Cogn Neurosci 16:1010-21. 2004..demonstrated that people with no formal music education process both contour and interval information in the auditory cortex automatically...
"Who" is saying "what"? Brain-based decoding of human voice and speechElia Formisano
Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, University of Maastricht, 6200 MD Maastricht, Netherlands
Science 322:970-3. 2008..a person is listening to from the neural fingerprints that speech and voice signals elicit in the listener's auditory cortex. These cortical fingerprints are spatially distributed and insensitive to acoustic variations of the input so ..
Hemispheric asymmetry for spectral and temporal processing in the human antero-lateral auditory belt cortexMarc Schönwiesner
Faculty of Biosciences, University of Leipzig, Germany
Eur J Neurosci 22:1521-8. 2005..The findings indicate that asymmetrical processing of complex sounds in the cerebral hemispheres does not depend on semantic, but rather on acoustic stimulus characteristics...
Modulation of the auditory cortex during speech: an MEG studyJohn F Houde
Center for Integrative Neuroscience, University of California, San Francisco 94143, USA
J Cogn Neurosci 14:1125-38. 2002..These data suggest that during speech production, the auditory cortex (1) attenuates its sensitivity and (2) modulates its activity as a function of the expected acoustic feedback.
Functional specificity in the right human auditory cortex for perceiving pitch directionI S Johnsrude
Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
Brain 123:155-63. 2000..These findings support a specialization of function linked to right auditory cortical areas for the processing of pitch direction, and specifically suggest a dissociation between simple sensory discrimination and higher order perception...
The role of auditory cortex in the formation of auditory streamsChristophe Micheyl
Department of Psychology, University of Minnesota, MN, USA
Hear Res 229:116-31. 2007..findings concerning the possible neural mechanisms behind this perceptual phenomenon at the level of the auditory cortex. The first part is devoted to intra-cortical recordings, which provide insight into the neural "..
Frequency-specific modulation of population-level frequency tuning in human auditory cortexHidehiko Okamoto
Institute for Biomagnetism and Biosignalanalysis, University of Muenster, Malmedyweg 15, 48149 Muenster, Germany
BMC Neurosci 10:1. 2009..random) under auditory focused attention by means of magnetoencephalography (MEG)...
Functional integration across brain regions improves speech perception under adverse listening conditionsJonas Obleser
Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, United Kingdom
J Neurosci 27:2283-9. 2007..These results demonstrate that increasing functional connectivity between high-order cortical areas, remote from the auditory cortex, facilitates speech comprehension when the clarity of speech is reduced.
Structural and functional asymmetry of lateral Heschl's gyrus reflects pitch perception preferencePeter Schneider
Department of Neurology, University Hospital Heidelberg, INF 400, D 69120 Heidelberg, Germany
Nat Neurosci 8:1241-7. 2005..Our data link relative hemispheric lateralization with perceptual stimulus properties, whereas the absolute size of the Heschl's gyrus depends on musical aptitude...
Laminar structure of spontaneous and sensory-evoked population activity in auditory cortexShuzo Sakata
Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
Neuron 64:404-18. 2009..cells, we compare the laminar structure of spontaneous and sensory-evoked population activity in rat auditory cortex. Spontaneous and evoked patterns both exhibited sparse, spatially localized activity in layer 2/3 pyramidal ..
Modular organization of intrinsic connections associated with spectral tuning in cat auditory cortexH L Read
W. M. Keck Center for Integrative Neuroscience, University of California, San Francisco, CA 94143, USA
Proc Natl Acad Sci U S A 98:8042-7. 2001Many response properties in primary auditory cortex (AI) are segregated spatially and organized topographically as those in primary visual cortex...
Tonotopic organization of human auditory cortexColin Humphries
Department of Neurology, Medical College of Wisconsin, Functional Imaging Research Center, Milwaukee, WI 53226, USA
Neuroimage 50:1202-11. 2010The organization of tonotopic fields in human auditory cortex was investigated using functional magnetic resonance imaging...
Cooperative nonlinearities in auditory cortical neuronsCraig A Atencio
University of California, San Francisco University of California, Berkeley Bioengineering Graduate Group, University of California, San Francisco, San Francisco, CA 94143, USA
Neuron 58:956-66. 2008..unclear which features of the acoustic environment are specifically represented by neurons in the primary auditory cortex (AI)...
Visual enhancement of the information representation in auditory cortexChristoph Kayser
Max Planck Institute for Biological Cybernetics, Spemannstrasse 38, 72076 Tubingen, Germany
Curr Biol 20:19-24. 2010..By recording in auditory cortex of alert monkeys watching naturalistic audiovisual stimuli, we quantified the effect of visual influences on ..
Corticofugal modulation of initial sound processing in the brainFeng Luo
Department of Physiology and Biophysics, Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
J Neurosci 28:11615-21. 2008..constitute the neural basis of such top-down selection? Here, we show how focal activation of the auditory cortex with 500 nA electrical pulses influences the auditory information processing in the cochlear nucleus (CN) ..
Enhancement of neuroplastic P2 and N1c auditory evoked potentials in musiciansAntoine Shahin
Unit of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, Ontario, Canada L8S 4K1
J Neurosci 23:5545-52. 2003..N1c components of the auditory evoked potential (AEP) have been shown to be sensitive to remodeling of the auditory cortex by training at pitch discrimination in nonmusician subjects...
Functional imaging reveals numerous fields in the monkey auditory cortexChristopher I Petkov
Max Planck Institute for Biological Cybernetics, Tubingen, Germany
PLoS Biol 4:e215. 2006Anatomical studies propose that the primate auditory cortex contains more fields than have actually been functionally confirmed or described...
The role of predictive models in the formation of auditory streamsS L Denham
Centre for Theoretical and Computational Neuroscience, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK
J Physiol Paris 100:154-70. 2006..We present new computational modelling results which replicate responses in primary auditory cortex [Fishman, Y.I., Arezzo, J.C., Steinschneider, M., 2004...
Neural correlates of auditory stream segregation in primary auditory cortex of the awake monkeyY I Fishman
Department of Neuroscience, Albert Einstein College of Medicine, Rose F Kennedy Center, Bronx, NY 10461, USA
Hear Res 151:167-187. 2001..These results parallel human psychoacoustics of auditory stream segregation and suggest a cortical basis for the perceptual phenomenon...
Vocalization-induced enhancement of the auditory cortex responsiveness during voice F0 feedback perturbationRoozbeh Behroozmand
Speech Physiology Laboratory, Department of Communication Science and Disorders, Northwestern University, 2240 Campus Drive, Evanston, IL 60208, USA
Clin Neurophysiol 120:1303-12. 2009....
Auditory cortex stimulation for tinnitusD de Ridder
Department of Neurosurgery and Otorhinolaryngology, University Hospital Antwerp, Belgium
Acta Neurochir Suppl 97:451-62. 2007..demonstrated a relationship between the intensity of tinnitus and the degree of reorganization of the primary auditory cortex. Studies in experimental animals and humans have revealed that tinnitus is associated with a synchronized ..
Dichotic pitch activates pitch processing centre in Heschl's gyrusSebastian Puschmann
Cognitive Neurobiology, Institute of Psychology, Carl von Ossietzky University Oldenburg, Oldenburg, Germany
Neuroimage 49:1641-9. 2010..These results support the view of a general representation of pitch in auditory cortex, irrespective of the physical attributes of the pitch-evoking sound.
Synaptic mechanisms underlying auditory processingAnne Marie M Oswald
Center for Neural Science, New York University, 4 Washington Place, Room 809, New York, NY 10003, USA
Curr Opin Neurobiol 16:371-6. 2006..recordings have provided new insights into the synaptic mechanisms that underlie processing in the primary auditory cortex. Of particular importance are the discoveries that excitatory and inhibitory inputs have similar frequency ..
A simple model of cortical dynamics explains variability and state dependence of sensory responses in urethane-anesthetized auditory cortexCarina Curto
Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
J Neurosci 29:10600-12. 2009..We show here that in auditory cortex of urethane-anesthetized rats, population responses to click stimuli can be quantitatively predicted on a ..
Changes of AI receptive fields with sound densityDavid T Blake
Coleman Laboratory and Keck Center for Integrative Neuroscience, Department of Otolaryngology, University of California, San Francisco, California 94143 0732, USA
J Neurophysiol 88:3409-20. 2002..In this study, optimal linear receptive fields were measured in alert primate primary auditory cortex (A1) in response to stimuli that vary in spectrotemporal density...
Associative learning shapes the neural code for stimulus magnitude in primary auditory cortexDaniel B Polley
Coleman Memorial Laboratory, W M Keck Center for Integrative Neuroscience, and Department of Otolaryngology, University of California, San Francisco, CA 94143, USA
Proc Natl Acad Sci U S A 101:16351-6. 2004..In the present study, we have investigated sound intensity coding in the rat primary auditory cortex (AI) and describe its plasticity by following paired stimulus reinforcement and instrumental conditioning ..
Modality-independent role of the primary auditory cortex in time estimationRyota Kanai
Institute of Cognitive Neuroscience and Department of Psychology, University College London, 17 Queen Square, London WC1N 3AR, UK
Exp Brain Res 209:465-71. 2011..time estimation, we hypothesized that early sensory areas such as the primary visual cortex or the auditory cortex might be involved in time perception independently of the sensory modality of the input...
Stimulus-specific adaptation and deviance detection in the rat auditory cortexNevo Taaseh
Department of Neurobiology, Silberman Institute of Life Sciences, Hebrew University, Jerusalem, Israel
PLoS ONE 6:e23369. 2011..We studied SSA in the auditory cortex of halothane-anesthetized rats, recording local field potentials and multi-unit activity...
Experience-dependent adult cortical plasticity requires cognitive association between sensation and rewardDavid T Blake
Center for Synapses and Cognitive Neuroscience, Department of Neurology, Medical College of Georgia, Augusta, Georgia 30912, USA
Neuron 52:371-81. 2006..These studies demonstrate that cognitive association between sensory stimuli and reinforcers accompanies adult experience-dependent cortical plasticity and suggest that selectivity in representation and action are linked...
Stimulus-specific adaptation in auditory cortex is an NMDA-independent process distinct from the sensory novelty encoded by the mismatch negativityBrandon J Farley
Department of Neuroscience, AstraZeneca Pharmaceuticals LP, Wilmington, Delaware 19850, USA
J Neurosci 30:16475-84. 2010..A leading candidate is stimulus-specific adaptation (SSA) in auditory cortex units, which shares several characteristics with the MMN...
An oscillatory hierarchy controlling neuronal excitability and stimulus processing in the auditory cortexPeter Lakatos
Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Inst, Orangeburg, New York 10962, USA
J Neurophysiol 94:1904-11. 2005..current source density CSD] and multiunit activity (MUA), both spontaneous and stimulus-driven, in primary auditory cortex of awake macaque monkeys...
Effect of behavioral context on representation of a spatial cue in core auditory cortex of awake macaquesBrian H Scott
Center for Neural Science, New York University, New York, New York 10003, USA
J Neurosci 27:6489-99. 2007Primary auditory cortex plays a crucial role in spatially directed behavior, but little is known about the effect of behavioral state on the neural representation of spatial cues...
Early stages of melody processing: stimulus-sequence and task-dependent neuronal activity in monkey auditory cortical fields A1 and RPingbo Yin
Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
J Neurophysiol 100:3009-29. 2008To explore the effects of acoustic and behavioral context on neuronal responses in the core of auditory cortex (fields A1 and R), two monkeys were trained on a go/no-go discrimination task in which they learned to respond selectively to ..
Architectonic identification of the core region in auditory cortex of macaques, chimpanzees, and humansT A Hackett
Department of Hearing and Speech Sciences, Vanderbilt University, 301 Wilson Hall, 111 21st Avenue South, Nashville, TN 37203, USA
J Comp Neurol 441:197-222. 2001....
Music and learning-induced cortical plasticityChristo Pantev
The Rotman Research Institute, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
Ann N Y Acad Sci 999:438-50. 2003Auditory stimuli are encoded by frequency-tuned neurons in the auditory cortex. There are a number of tonotopic maps, indicating that there are multiple representations, as in a mosaic...
Speaking modifies voice-evoked activity in the human auditory cortexG Curio
Low Temperature Laboratory, Helsinki University of Technology, Espoo, Finland
Hum Brain Mapp 9:183-91. 2000..Using magnetoencephalograpy we show here that self-uttered syllables transiently activate the speaker's auditory cortex around 100 ms after voice onset...
Timbre-specific enhancement of auditory cortical representations in musiciansC Pantev
Biomagnetism Center, Institute for Experimental Audiology, , Germany
Neuroreport 12:169-74. 2001..Timbre specificity is predicted by a principle of use-dependent plasticity and imposes new requirements on nativistic accounts of brain attributes associated with musical skill...
Novelty detector neurons in the mammalian auditory midbrainDavid Pérez-González
Auditory Neurophysiology Unit, Laboratory for the Neurobiology of Hearing, Faculty of Medicine, University of Salamanca and Institute for Neuroscience of Castilla y León, Salamanca, Spain
Eur J Neurosci 22:2879-85. 2005..The finding of neurons that respond selectively to novel stimuli in the mammalian auditory midbrain suggests that they may contribute to a rapid subcortical pathway for directing attention and/or orienting responses to novel sounds...
A neural representation of pitch salience in nonprimary human auditory cortex revealed with functional magnetic resonance imagingHector Penagos
Speech and Hearing Bioscience and Technology Program, Harvard Massachusetts Institute of Technology, Division of Health Sciences and Technology, Cambridge, Massachusetts 02139, USA
J Neurosci 24:6810-5. 2004..Cochlear nucleus, inferior colliculus, and primary auditory cortex did not show significant differences in activation level between conditions...
Endogenous cortical rhythms determine cerebral specialization for speech perception and productionAnne Lise Giraud
INSERM, U742, Paris, F 75005, France
Neuron 56:1127-34. 2007..These data show that endogenous cortical rhythms provide temporal and spatial constraints on the neuronal mechanisms underlying speech perception and production...
Selectivity and localization of cortical response to auditory and visual stimulation in awake infants aged 2 to 4 monthsGentaro Taga
Graduate School of Education, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
Neuroimage 36:1246-52. 2007..These results indicate that localized areas of the primary auditory cortex and the auditory association cortex are involved in auditory perception in infants as young as 2 months of ..
Subdivisions of auditory cortex and processing streams in primatesJ H Kaas
Department of Psychology, Vanderbilt University, Nashville, TN 37240, USA
Proc Natl Acad Sci U S A 97:11793-9. 2000..Histochemically, chimpanzees and humans have an auditory core that closely resembles that of monkeys. The challenge for future researchers is to understand how this complex system in monkeys analyzes and utilizes auditory information...
Specific long-term memory traces in primary auditory cortexNorman M Weinberger
Center for the Neurobiology of Learning and Memory and Department of Neurobiology and Behavior, University of California Irvine, Irvine, California 92797-3800, USA
Nat Rev Neurosci 5:279-90. 2004
Cortical convergence from different frequency domains in the cat primary auditory cortexH Ojima
Cortical Organization and Systematics, RIKEN, BSI, 2 1 Hirosawa, Wako, Saitama, 351 0198 Japan
Neuroscience 126:203-12. 2004Primary auditory cortex (AI) has a tonotopic map consisting of orderly isofrequency (IF) bands, and cortical connections are commonly supposed to link domains preferring similar characteristic frequencies (CFs) within AI and in auditory ..
Effects of feature-selective attention on auditory pattern and location processingChristian F Altmann
Institute of Medical Psychology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
Neuroimage 41:69-79. 2008..Given that the location matching task was significantly more difficult than the pattern matching, our data suggest that frontal and insular regions were modulated by task difficulty rather than feature-specific attention...
Motor-induced suppression of the auditory cortexSheye O Aliu
University of California San Francisco, USA
J Cogn Neurosci 21:791-802. 2009..In three MEG experiments, we characterize the properties of MIS by examining the M100 response from the auditory cortex to a simple tone triggered by a button press...
Task difficulty and performance induce diverse adaptive patterns in gain and shape of primary auditory cortical receptive fieldsSerin Atiani
Neuroscience and Cognitive Sciences Program, University of Maryland, College Park, MD 20742, USA
Neuron 61:467-80. 2009..of this perceptual ability by measuring rapid changes of spectrotemporal receptive fields (STRFs) in primary auditory cortex during detection of a target tone embedded in noise...
Neuromagnetic correlates of streaming in human auditory cortexAlexander Gutschalk
Department of Neurology, University of Heidelberg, 69120 Heidelberg, Germany
J Neurosci 25:5382-8. 2005..correlation between listeners' perception and long-latency (>60 ms) activity that likely arises in nonprimary auditory cortex. The second demonstrated a covariation between this activity and listeners' perception in the absence of ..
Functional role of auditory cortex in frequency processing and pitch perceptionMark Jude Tramo
Department of Neurology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts 02114 2696, USA
J Neurophysiol 87:122-39. 2002Microelectrode studies in nonhuman primates and other mammals have demonstrated that many neurons in auditory cortex are excited by pure tone stimulation only when the tone's frequency lies within a narrow range of the audible spectrum...
Left auditory cortex gamma synchronization and auditory hallucination symptoms in schizophreniaKevin M Spencer
Research Service, Veterans Affairs Boston Healthcare System and Department of Psychiatry, Harvard Medical School, Research 151C, 150 S, Huntington Ave, Boston, MA 02130, USA
BMC Neurosci 10:85. 2009..hypothesis by examining whether the 40 Hz auditory steady-state response (ASSR) generated in the left primary auditory cortex is positively correlated with auditory hallucination symptoms in schizophrenia...
Environmental noise retards auditory cortical developmentEdward F Chang
W M Keck Center for Integrative Neuroscience, University of California, San Francisco, CA, USA
Science 300:498-502. 2003The mammalian auditory cortex normally undergoes rapid and progressive functional maturation...
Spinogenesis and pruning in the primary auditory cortex of the macaque monkey (Macaca fascicularis): an intracellular injection study of layer III pyramidal cellsGuy N Elston
Centre for Cognitive Neuroscience, 60 Duke Rd, Doonan, Sunshine Coast, Queensland, 4562, Australia
Brain Res 1316:35-42. 2010..in pyramidal cell growth profiles we expanded the bases for comparison by studying neurons in the primary auditory cortex (A1)...
Tone-sequence analysis in the auditory cortex of awake macaque monkeysMichael Brosch
Leibniz Institut für Neurobiologie, Brenneckestrasse 6, 3911, Magdeburg, Germany
Exp Brain Res 184:349-61. 2008The present study analyzed neuronal responses to two-tone sequences in the auditory cortex of three awake macaque monkeys...
Active stream segregation specifically involves the left human auditory cortexSusann Deike
Leibniz Institute for Neurobiology, Brenneckestr 6, 39118 Magdeburg, Germany
Hear Res 265:30-7. 2010..the active segregation of the A from the B stream led to a selective increase of activation in the left auditory cortex (AC)...
Auditory temporal resolution in children assessed by magnetoencephalographyJennifer Diedler
Department of Neurology, Section of Biomagnetism, University of Heidelberg, Heidelberg, Germany
Neuroreport 18:1691-5. 2007..AEFs thus provide an objective tool to assess auditory temporal resolution in children. Children's neuromagnetic response patterns differed significantly from the adult responses under the same experimental conditions...
A recovery from enhancement of activation in auditory cortex of patients with idiopathic sudden sensorineural hearing lossT Morita
Department of Otolaryngology, Shizuoka General Hospital, 420 8527 Shizuoka, Japan
Neurosci Res 58:6-11. 2007We previously reported enhanced activation of auditory cortex in patients with bilateral chronic inner-ear hearing loss...
Influence of physical parameters of sound on the sensory gating effects of N40 in ratsDongming Zhou
State Key Laboratory of Brain and Cognitive Science, Graduate University, Chinese Academy of Sciences and Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, PR China
Neurosci Lett 432:100-4. 2008..The greater the physical difference between S1 and S2, the more the gating effect was affected...
Human cortical activity during streaming without spectral cues suggests a general neural substrate for auditory stream segregationAlexander Gutschalk
Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
J Neurosci 27:13074-81. 2007..We hypothesize that feature-specific forward suppression subserves streaming based on diverse perceptual cues and results in explicit neural representations for auditory streams within auditory cortex.
Primary motor area contribution to attentional reorienting after distractionJános Horváth
Institute for Psychology I, University of Leipzig, Germany
Neuroreport 19:443-6. 2008..In the reorienting negativity interval, significant activity was located in the primary motor area. This suggests that action-selection-related activity also contributes to attentional reorientation after distraction...
Depth electrode recordings show double dissociation between pitch processing in lateral Heschl's gyrus and sound onset processing in medial Heschl's gyrusMarc Schönwiesner
Laboratory for Brain, Music and Sound Research BRAMS, Montreal, Canada
Exp Brain Res 187:97-105. 2008..Our results provide direct evidence for a pitch-specific area on lateral STP with intracranial recordings from the human auditory cortex.
Research Grants
- Plasticity of Auditory Cortical Circuits in SchizophreniaRobert Sweet; Fiscal Year: 2009..Tone discrimination depends on excitatory connections amongst networks of layer 3 pyramidal cells in primary auditory cortex (AI)...
- Plasticity of Auditory Cortical Circuits in SchizophreniaRobert A Sweet; Fiscal Year: 2010..Tone discrimination depends on excitatory connections amongst networks of layer 3 pyramidal cells in primary auditory cortex (AI)...
- FUNCTIONAL ORGANIZATION OF PRIMARY AUDITORY CORTEXChristoph E Schreiner; Fiscal Year: 2011..We attempt to explore the normal function of the auditory cortex for processing complex signals and signals in different types of background noise in order to ascertain the ..
- Integration of ascending and descending input to auditory cortexMatthew I Banks; Fiscal Year: 2010..Here, we propose to investigate the cellular and circuit mechanisms of this integrative process in auditory cortex and its modulation by general anesthetics...
- Adaptation to Unilateral Hearing Loss in Humans: Cortical and Perceptual EffectsPeter Gordon; Fiscal Year: 2007The goal of this project is to increase understanding of adaptation in human auditory cortex after peripheral hearing loss in adults...
- Integration of ascending and descending input to auditory cortexMatthew Banks; Fiscal Year: 2009..Here, we propose to investigate the cellular and circuit mechanisms of this integrative process in auditory cortex and its modulation by general anesthetics...
- Cortical Sensitivity to Acoustic Cues for Sound LocationEWAN MACPHERSON; Fiscal Year: 2006Sound localization is a fundamental task of the auditory system, and in higher mammals, requires an intact auditory cortex. Many cortical neurons respond over broad regions of space and vary the rate and temporal pattern of their ..
- Feature selectivity of auditory thalamusEdward Bartlett; Fiscal Year: 2005..arise from the MGB representations, given the comparatively large body of knowledge regarding responses of auditory cortex neurons to auditory stimuli...
- GABAergic Circuits in Auditory CortexMatthew Banks; Fiscal Year: 2006..In this proposal, we seek to understand how GABAergic cells control the timing of action potentials in auditory cortex (ACx)...
- GABAergic Circuits in Auditory CortexMatthew Banks; Fiscal Year: 2003..In this proposal, we seek to understand how GABAergic cells control the timing of action potentials in auditory cortex (ACx)...
- Technological Development Towards a Cortical ProsthesisPatrick Rousche; Fiscal Year: 2005..Preliminary evidence suggests that direct electrical stimulation of the human auditory cortex can induce auditory perceptions...
- Neural mechanisms of auditory feedback during speechSrikantan Nagarajan; Fiscal Year: 2007..Recent studies have shown that in auditory cortex and other areas in the superior temporal plane, speaking causes "speaking-induced suppression" (SIS): ..
- Influences of developmental hearing loss on auditory perception and neural codingMERRI ROSEN; Fiscal Year: 2007..is that mild to moderate conductive HL during development permanently disrupts coding properties in the auditory cortex, leading to measurable deficits in perceptual performance. There are three related experimental aims...
- Functional organization of auditory corticothalamic projection systemsDaniel Llano; Fiscal Year: 2007..Summary: The objective of the proposed studies is to understand the functional relationships between the auditory cortex and thalamus, and ultimately to uncover the neural substrates for auditory cognition...
- PARALLEL AUDITORY PATHWAYS IN THE BRAIN STEMEllen Covey; Fiscal Year: 2006..multiple auditory centers in the lower brainstem, from non-ascending auditory inputs from the opposite IC and auditory cortex and from motor-related structures...
- PARALLEL AUDITORY PATHWAYS IN THE BRAIN STEMJOHN CASSEDAY; Fiscal Year: 2005..multiple auditory centers in the lower brainstem, from non-ascending auditory inputs from the opposite IC and auditory cortex and from motor-related structures...
- STRUCTURE OF PRIMARY AUDITORY CORTEXJEFFERY WINER; Fiscal Year: 2007..experiments will chart the connections between the inferior colliculus (IC), medial geniculate body (MGB) and auditory cortex (AC), three structures essential for normal hearing...
- STRUCTURE OF PRIMARY AUDITORY CORTEXJEFFERY WINER; Fiscal Year: 2000This is a proposal to study the structure, connections, and neurochemical organization of the primary auditory cortex (AI), medial geniculate body, and inferior colliculus in several species...
- GABAergic Circuits in Auditory CortexMatthew Banks; Fiscal Year: 2007..In this proposal, we seek to understand how GABAergic cells control the timing of action potentials in auditory cortex (ACx)...
- CRCNS: Dynamics of the auditory cortical columnGyorgy Buzsaki; Fiscal Year: 2010The auditory cortex is a critical structure for processing of sound information in mammals...
- STRUCTURE OF PRIMARY AUDITORY CORTEXJEFFERY WINER; Fiscal Year: 2005DESCRIPTION: (Adapted from applicant's abstract): A series of studies are proposed that will analyze how auditory cortex, the medial geniculate body, and the inferior colliculus are interrelated anatomically...
- Single-unit response to AM sound in the auditory cortex.Mamiko Niwa; Fiscal Year: 2007..We will record single-units responses in the primary auditory cortex (A1) and the middle-lateral field of the auditory cortex (ML) of non-human subjects while they actively ..
- CRCNS: Dynamics of the auditory cortical columnKenneth Harris; Fiscal Year: 2009The auditory cortex is a critical structure for processing of sound information in mammals...
- Auditory Cortical Processing of Communication SoundsKamal Sen; Fiscal Year: 2009b>Auditory cortex plays an important role in the processing of complex sounds e.g., vocal communication sounds and human speech...
- Auditory Cortical Processing of Communication SoundsKamal Sen; Fiscal Year: 2007b>Auditory cortex plays an important role in the processing of complex sounds e.g., vocal communication sounds and human speech...
- Auditory Cortical Processing of Communication SoundsKAMAL K SEN; Fiscal Year: 2010b>Auditory cortex plays an important role in the processing of complex sounds e.g., vocal communication sounds and human speech...
