Genomes and Genes
Summary: The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon and folds into gyri. It reaches its highest development in man and is responsible for intellectual faculties and higher mental functions.
Publications198 found, 100 shown here
- Neurophysiological and computational principles of cortical rhythms in cognitionXiao Jing Wang
Department of Neurobiology and Kavli Institute of Neuroscience, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Physiol Rev 90:1195-268. 2010..This review focuses on oscillations in the cerebral cortex that occur during cognition, in alert behaving conditions...
- Modelling the magnetic signature of neuronal tissueK B Blagoev
Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM 87544, USA
Neuroimage 37:137-48. 2007..MRI contrast generation based on neuronal currents depends on the dendritic architecture and we obtained high-resolution optical images of cortical tissue to discuss the spatial structure of the magnetic field in grey matter...
- Neural correlates of regional EEG power changeN Oishi
Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto 606 8507, Japan
Neuroimage 36:1301-12. 2007..The neural network including the prefrontal cortex could play an important role to generate the EEG rhythm...
- Cortical control of zona incertaPeter Bartho
Institute of Experimental Medicine, Hungarian Academy of Sciences, 1450 Budapest, Hungary
J Neurosci 27:1670-81. 2007..We propose that the efferent GABAergic signal of ZI neurons patterned by the cortical activity can play a critical role in synchronizing thalamocortical and brainstem rhythms...
- White matter abnormalities and brain activation in schizophrenia: a combined DTI and fMRI studyRalf G M Schlösser
Department of Psychiatry and Psychotherapy, Friedrich Schiller University, 07743 Jena, Germany
Schizophr Res 89:1-11. 2007..It highlights a potential relationship between anatomical changes in a frontal-temporal anatomical circuit and functional alterations in the prefrontal cortex...
- Control of goal-directed and stimulus-driven attention in the brainMaurizio Corbetta
Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Nat Rev Neurosci 3:201-15. 2002..This ventral frontoparietal network works as a 'circuit breaker' for the dorsal system, directing attention to salient events. Both attentional systems interact during normal vision, and both are disrupted in unilateral spatial neglect...
- Mapping the structural core of human cerebral cortexPatric Hagmann
Department of Radiology, University Hospital Center and University of Lausanne CHUV, Lausanne, Switzerland
PLoS Biol 6:e159. 2008Structurally segregated and functionally specialized regions of the human cerebral cortex are interconnected by a dense network of cortico-cortical axonal pathways...
- Neuronal oscillations in cortical networksGyorgy Buzsaki
Center for Molecular and Behavioral Neuroscience, Rutgers, State University of New Jersey, Newark, NJ 07102, USA
Science 304:1926-9. 2004....
- Cortical surface-based analysis. I. Segmentation and surface reconstructionA M Dale
Massachusetts General Hosp Harvard Medical School, Building 149, Charlestown, Massachusetts, 02129, USA
Neuroimage 9:179-94. 1999Several properties of the cerebral cortex, including its columnar and laminar organization, as well as the topographic organization of cortical areas, can only be properly understood in the context of the intrinsic two-dimensional ..
- How do you feel--now? The anterior insula and human awarenessA D Bud Craig
Atkinson Research Laboratory, Barrow Neurological Institute, Phoenix, Arizona 85013, USA
Nat Rev Neurosci 10:59-70. 2009..New findings suggest a fundamental role for the AIC (and the von Economo neurons it contains) in awareness, and thus it needs to be considered as a potential neural correlate of consciousness...
- A resilient, low-frequency, small-world human brain functional network with highly connected association cortical hubsSophie Achard
Wolfson Brain Imaging Centre, University of Cambridge, Department of Psychiatry, Addenbrooke's Hospital, Cambridge CB2 2QQ, United Kingdom
J Neurosci 26:63-72. 2006..Because the major hubs of this network are critical for cognition, its slow dynamics could provide a physiological substrate for segregated and distributed information processing...
- Mapping anatomical connectivity patterns of human cerebral cortex using in vivo diffusion tensor imaging tractographyGaolang Gong
Department of Biomedical Engineering, 1098 Research Transition Facility, University of Alberta, Edmonton, Alberta, Canada
Cereb Cortex 19:524-36. 2009..to construct a macroscale anatomical network capturing the underlying common connectivity pattern of human cerebral cortex in a large sample of subjects (80 young adults) and further quantitatively analyzed its topological ..
- Predicting human resting-state functional connectivity from structural connectivityC J Honey
Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, USA
Proc Natl Acad Sci U S A 106:2035-40. 2009In the cerebral cortex, the activity levels of neuronal populations are continuously fluctuating...
- The cortical organization of speech processingGregory Hickok
Department of Cognitive Sciences and The Center for Cognitive Neuroscience, University of California, Irvine, California 92697 5100, USA
Nat Rev Neurosci 8:393-402. 2007....
- Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's diseaseRandy L Buckner
Department of Psychology and Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA
J Neurosci 29:1860-73. 2009..To identify regions of high connectivity in the human cerebral cortex, we applied a computationally efficient approach to map the degree of intrinsic functional connectivity ..
- Cortical networks for working memory and executive functions sustain the conscious resting state in manB Mazoyer
Groupe d'Imagerie Neurofonctionnelle, UMR6095, CNRS, LEA, , , Paris, France
Brain Res Bull 54:287-98. 2001....
- The neuroscience of tinnitusJos J Eggermont
Department of Physiology and Biophysics, and Department of Psychology, University of Calgary, Alberta, Canada T2N 1N4
Trends Neurosci 27:676-82. 2004..Downregulation of intracortical inhibition induced by damage to the cochlea or to auditory projection pathways highlights neural processes that underlie the sensation of phantom sound...
- The neural bases of momentary lapses in attentionD H Weissman
Center for Cognitive Neuroscience and Department of Psychiatry, Duke University, Durham, North Carolina 27708, USA
Nat Neurosci 9:971-8. 2006..Our findings provide a new, system-wide understanding of the patterns of brain activity that are associated with brief attentional lapses, which informs both theoretical and clinical models of goal-directed behavior...
- Probabilistic decision making by slow reverberation in cortical circuitsXiao Jing Wang
Volen Center for Complex Systems, Brandeis University, Waltham, MA 02254, USA
Neuron 36:955-68. 2002....
- An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interestRahul S Desikan
Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, W701, Boston, MA 02118, USA
Neuroimage 31:968-80. 2006..the validity and reliability of an automated labeling system that we have developed for subdividing the human cerebral cortex on magnetic resonance images into gyral based regions of interest (ROIs)...
- The small world of the cerebral cortexOlaf Sporns
Department of Psychology, Indiana University, Bloomington 47405, USA
Neuroinformatics 2:145-62. 2004While much information is available on the structural connectivity of the cerebral cortex, especially in the primate, the main organizational principles of the connection patterns linking brain areas, columns and individual cells have ..
- Parvalbumin neurons and gamma rhythms enhance cortical circuit performanceVikaas S Sohal
Department of Bioengineering, Stanford University, Stanford, California 94305, USA
Nature 459:698-702. 2009....
- Automatically parcellating the human cerebral cortexBruce Fischl
Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, MGH MIT Harvard Medical School, Massachusetts General Hospital, 13th Street, Charlestown, MA 02129, USA
Cereb Cortex 14:11-22. 2004..Examples are given from two different training sets generated using different neuroanatomical conventions, illustrating the flexibility of the algorithm. The technique is shown to be comparable in accuracy to manual labeling...
- A Population-Average, Landmark- and Surface-based (PALS) atlas of human cerebral cortexDavid C Van Essen
Department of Anatomy and Neurobiology, Washington University School of Medicine, 660 S Euclid Ave, Box 8108, St Louis, MO 63110, USA
Neuroimage 28:635-62. 2005This report describes a new electronic atlas of human cerebral cortex that provides a substrate for a wide variety of brain-mapping analyses...
- Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-betaT Nakagawa
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
Nature 403:98-103. 2000..Thus, caspase-12 mediates an ER-specific apoptosis pathway and may contribute to amyloid-beta neurotoxicity...
- Three-dimensional probabilistic anatomical cranio-cerebral correlation via the international 10-20 system oriented for transcranial functional brain mappingMasako Okamoto
National Food Research Institute, Tsukuba 305-8642, Japan
Neuroimage 21:99-111. 2004..This study provided an initial step toward establishing a three-dimensional probabilistic anatomical platform that enables intra- and intermodal comparisons of NIRS and TMS brain imaging data...
- Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phasesStephen C Noctor
Department of Neurology, Columbia University College of Physicians and Surgeons, 630 W 168th Street, New York, New York 10032, USA
Nat Neurosci 7:136-44. 2004..division and migration are crucial to transform the neuroepithelium of the embryonic forebrain into the adult cerebral cortex. Using time-lapse imaging of clonal cells in rat cortex over several generations, we show here that neurons ..
- The mismatch negativity (MMN) in basic research of central auditory processing: a reviewR Naatanen
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Helsinki, Finland
Clin Neurophysiol 118:2544-90. 2007..In addition, the MMN enables one to establish the brain processes underlying the initiation of attention switch to, conscious perception of, sound change in an unattended stimulus stream...
- Analysis of functional image analysis contest (FIAC) data with brainvoyager QX: From single-subject to cortically aligned group general linear model analysis and self-organizing group independent component analysisRainer Goebel
Brain Innovation, Maastricht, The Netherlands
Hum Brain Mapp 27:392-401. 2006..Using spatially and temporally unsmoothed data, this cortex-based analysis revealed comparable results but with a set of spatially more confined group clusters and more differential group region of interest time courses...
- Neuroanatomy of autismDavid G Amaral
The M I N D Institute, Department of Psychiatry and Behavioral Sciences, University of California, Davis, 2825 50th Street, Sacramento, CA 95817, USA
Trends Neurosci 31:137-45. 2008..Defined phenotypes in larger samples of children and well-characterized brain tissue will be necessary for clarification of the neuroanatomy of autism...
- Circuitry and functional aspects of the insular lobe in primates including humansJ R Augustine
Department of Cell Biology and Neuroscience, University of South Carolina School of Medicine, Columbia 29208, USA
Brain Res Brain Res Rev 22:229-44. 1996..Recent studies have expanded the role of the insula as a somatosensory area, emphasizing its multifaceted, sensory role. The idea of the insula as limbic integration cortex has been affirmed and its role in Alzheimer's disease suggested...
- A theory of cortical responsesKarl Friston
The Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
Philos Trans R Soc Lond B Biol Sci 360:815-36. 2005..The final focus of this article is on perceptual learning as measured with the MMN and the implications for empirical studies of coupling among cortical areas using evoked sensory responses...
- Neural simulation of action: a unifying mechanism for motor cognitionM Jeannerod
Institut des Sciences Cognitives, 67 Boulevard Pinel, Bron, 69675, France
Neuroimage 14:S103-9. 2001..The function of this process of simulation would be not only to shape the motor system in anticipation to execution, but also to provide the self with information on the feasibility and the meaning of potential actions...
- Distinct brain networks for adaptive and stable task control in humansNico U F Dosenbach
Department of Radiology, Washington University, St Louis, MO 63110, USA
Proc Natl Acad Sci U S A 104:11073-8. 2007..These two independent networks appear to operate on different time scales and affect downstream processing via dissociable mechanisms...
- Neurodevelopmental trajectories of the human cerebral cortexPhilip Shaw
Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
J Neurosci 28:3586-94. 2008Understanding the organization of the cerebral cortex remains a central focus of neuroscience. Cortical maps have relied almost exclusively on the examination of postmortem tissue to construct structural, architectonic maps...
- Neural activity in the human brain relating to uncertainty and arousal during anticipationH D Critchley
Wellcome Department of Cognitive Neurology, 12 Queen Square, Institute of Neurology, University College London, WC1N 3BG, London, United Kingdom
Neuron 29:537-45. 2001..Our findings highlight distinct contributions of cognitive uncertainty and autonomic arousal to anticipatory neural activity in prefrontal cortex...
- Theoretical neuroanatomy: relating anatomical and functional connectivity in graphs and cortical connection matricesO Sporns
The Neurosciences Institute, 10640 John Jay Hopkins Drive, San Diego, CA 92121, USA
Cereb Cortex 10:127-41. 2000Neuroanatomy places critical constraints on the functional connectivity of the cerebral cortex. To analyze these constraints we have examined the relationship between structural features of networks (expressed as graphs) and the patterns ..
- Human insula activation reflects risk prediction errors as well as riskKerstin Preuschoff
Computation and Neural Systems Program and Division of Humanities and Social Sciences, Caltech, Pasadena, California 91125, USA
J Neurosci 28:2745-52. 2008..As such, our findings indicate that our understanding of the neural basis of reward anticipation under uncertainty needs to be expanded to include risk prediction...
- Grouping of brain rhythms in corticothalamic systemsM Steriade
Laboratory of Neurophysiology, Laval University, Faculty of Medicine, Quebec, Canada G1K 7P4
Neuroscience 137:1087-106. 2006....
- Mapping directed influence over the brain using Granger causality and fMRIAlard Roebroeck
Department of Cognitive Neuroscience, Faculty of Psychology, University of Maastricht, The Netherlands
Neuroimage 25:230-42. 2005..The presented exploratory approach of mapping influences between a region of interest and the rest of the brain can form a useful complement to existing models of effective connectivity...
- GABAergic depolarization of the axon initial segment in cortical principal neurons is caused by the Na-K-2Cl cotransporter NKCC1Stanislav Khirug
Department of Biological and Environmental Sciences, University of Helsinki, FIN 00014 Helsinki, Finland
J Neurosci 28:4635-9. 2008..Our findings demonstrate that spatially distinct interneuronal inputs can induce postsynaptic voltage responses with different amplitudes and polarities as governed by the subcellular distributions of plasmalemmal chloride transporters...
- Increased activation in the right insula during risk-taking decision making is related to harm avoidance and neuroticismMartin P Paulus
Laboratory of Biological Dynamics and Theoretical Medicine, Department of Psychiatry, University of California San Diego, La Jolla, CA 92093 0603, USA
Neuroimage 19:1439-48. 2003..These results are consistent with the hypothesis that insula activation serves as a critical neural substrate to instantiate aversive somatic markers that guide risk-taking decision-making behavior...
- The representation of object concepts in the brainAlex Martin
Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, Maryland 20892 1366, USA
Annu Rev Psychol 58:25-45. 2007..However, some property-based regions seem to show a categorical organization, thus providing evidence consistent with category-based, domain-specific formulations as well...
- Dynamic I-V curves are reliable predictors of naturalistic pyramidal-neuron voltage tracesLaurent Badel
Laboratory of Computational Neuroscience, School of Computer and Communication Sciences and Brain Institute, Lausanne, Switzerland
J Neurophysiol 99:656-66. 2008..The predictions of the resulting model are in excellent agreement with experimental data and close to the intrinsic neuronal reproducibility to repeated stimuli...
- Perisomatic inhibitionTamas F Freund
Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
Neuron 56:33-42. 2007Recent evidence supports the hypothesis of a functional dichotomy of perisomatic inhibition in the cerebral cortex: the parvalbumin- and cholecystokinin-containing basket cells that are specialized to control rhythm (as a clockwork) and &..
- Excitatory actions of GABA in the cortexAllan T Gulledge
Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Mills Road, Canberra, ACT 0200, Australia
Neuron 37:299-309. 2003..Our findings demonstrate that under certain circumstances GABA will have an excitatory role in synaptic integration in the cortex...
- Psychological and neural mechanisms of the affective dimension of painD D Price
Department of Oral and Maxillofacial Surgery, University of Florida, Health Science Center, Post Office Box 100416, Gainesville, FL 32610 0416, USA
Science 288:1769-72. 2000..Both direct and cortico-limbic pathways converge on the same anterior cingulate cortical and subcortical structures whose function may be to establish emotional valence and response priorities...
- Brain activity varies with modulation of dynamic pitch variance in sentence melodyMartin Meyer
Max Planck Institute of Cognitive Neuroscience, Leipzig, Germany
Brain Lang 89:277-89. 2004..Finally, it appears that brain areas which subserve speech (frontal operculum) and premotor functions (Rolandic operculum) coincidently support the processing of intonation contour in spoken sentence comprehension...
- Thermosensory activation of insular cortexA D Craig
Division of Neurosurgery, Barrow Neurological Institute, 350 West Thomas Rd, Phoenix, Arizona 85013, USA
Nat Neurosci 3:184-90. 2000..Notably, perceived thermal intensity was well correlated with activation in the right (ipsilateral) anterior insular and orbitofrontal cortices...
- From sensation to cognitionM M Mesulam
Department of Neurology, Northwestern University Medical School, Chicago 60611, USA
Brain 121:1013-52. 1998..the primary sensory, upstream unimodal, downstream unimodal, heteromodal, paralimbic and limbic zones of the cerebral cortex. Connections from one zone to another are reciprocal and allow higher synaptic levels to exert a feedback (..
- Cortical midline structures and the selfGeorg Northoff
Laboratory for Magnetic Brain Stimulation, Division of Behavioral Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Trends Cogn Sci 8:102-7. 2004..All of these subfunctions are related to distinct regions within the CMS. This relationship between self-referential processing and CMS might provide novel insight into the neural correlates underlying the constitution of the self...
- Neuronal and glial localization of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter, in human cerebral cortex: with a note on its distribution in monkey cortexF Conti
Institute of Human Physiology, University of Ancona, Italy
J Comp Neurol 396:51-63. 1998..membrane transporters (GATs) influence the action of GABA, the main inhibitory neurotransmitter in the human cerebral cortex. In this study, the cellular expression of GAT-1, the main cortical GABA transporter, was investigated in the ..
- Painful stimuli evoke different stimulus-response functions in the amygdala, prefrontal, insula and somatosensory cortex: a single-trial fMRI studyK Bornhovd
Cognitive Neuroscience Laboratory, Department of Neurology, Hamburg University Medical School, Germany
Brain 125:1326-36. 2002..e. 'uncertain' trials), the evoked signal changes were as great as in P3 trials, indicating that the amygdala is involved in coding 'uncertainty', as has been suggested previously in relation to classical conditioning...
- Dopamine regulates the impact of the cerebral cortex on the subthalamic nucleus-globus pallidus networkP J Magill
Medical Research Council Anatomical Neuropharmacology Unit, University of Oxford, Mansfield Road, Oxford OX1 3TH, UK
Neuroscience 106:313-30. 2001..Furthermore, the relative contribution of rate and pattern to aberrant information coding is intimately related to the state of activation of the cerebral cortex.
- An integrated software suite for surface-based analyses of cerebral cortexD C Van Essen
Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Am Med Inform Assoc 8:443-59. 2001..describe and illustrate an integrated trio of software programs for carrying out surface-based analyses of cerebral cortex. The first component of this trio, SureFit (Surface Reconstruction by Filtering and Intensity Transformations)..
- Simulation of robustness against lesions of cortical networksMarcus Kaiser
School of Computing Science, University of Newcastle, Claremont Tower, Newcastle upon Tyne NE1 7RU, UK
Eur J Neurosci 25:3185-92. 2007..This informs the understanding of the development of connectivity of the brain networks...
- Human SII and posterior insula differently encode thermal laser stimuliMaud Frot
Institut National de la Santé et de la recherche médicale 342, Bron F 69677, France
Cereb Cortex 17:610-20. 2007....
- An intrinsic mechanism of corticogenesis from embryonic stem cellsNicolas Gaspard
IRIBHM Institute for Interdisciplinary Research, Universite Libre de Bruxelles ULB
Nature 455:351-7. 2008The cerebral cortex develops through the coordinated generation of dozens of neuronal subtypes, but the mechanisms involved remain unclear...
- Empathy for pain involves the affective but not sensory components of painTania Singer
Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College of London, 12 Queen Square, WC1N 3AR London, UK
Science 303:1157-62. 2004..quot; We conclude that only that part of the pain network associated with its affective qualities, but not its sensory qualities, mediates empathy...
- Faces and objects in macaque cerebral cortexDoris Y Tsao
Athinoula A Martinos Center, Charlestown, Massachusetts 02129, USA
Nat Neurosci 6:989-95. 2003..Overall, our results suggest that humans and macaques share a similar brain architecture for visual object processing...
- The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cellsYusuke Hirabayashi
Institute of Molecular and Cellular Biosciences, University of Tokyo, 1 1 1 Yayoi, Bunkyo ku, Tokyo 113 0032, Japan
Development 131:2791-801. 2004..These findings may reveal broader and stage-specific physiological roles of Wnt signaling during neural development...
- Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortexJoshua T Trachtenberg
Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
Nature 420:788-94. 2002..Our measurements suggest that sensory experience drives the formation and elimination of synapses and that these changes might underlie adaptive remodelling of neural circuits...
- The determination of projection neuron identity in the developing cerebral cortexDino P Leone
Department of Biology, Stanford University, Stanford, CA 94305, USA
Curr Opin Neurobiol 18:28-35. 2008..Pyramidal neurons in the mammalian cerebral cortex can be classified into two major classes: corticocortical projection neurons, which are concentrated in the ..
- Object recognition memory: neurobiological mechanisms of encoding, consolidation and retrievalBoyer D Winters
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
Neurosci Biobehav Rev 32:1055-70. 2008..Recent studies in rodents have begun to indicate the remarkable complexity of the neural substrates underlying this seemingly simple aspect of declarative memory...
- Identifying neural drivers with functional MRI: an electrophysiological validationOlivier David
INSERM, U836, Grenoble Institut des Neurosciences, Grenoble, France
PLoS Biol 6:2683-97. 2008..As such, it has important implications for future studies on brain connectivity using functional neuroimaging...
- A surface-based analysis of hemispheric asymmetries and folding of cerebral cortex in term-born human infantsJason Hill
Departments of Pediatrics, Anatomy and Neurobiology, and Mechanical, Aerospace, and Structural Engineering, Washington University School of Medicine, St Louis, Missouri 63108, USA
J Neurosci 30:2268-76. 2010We have established a population average surface-based atlas of human cerebral cortex at term gestation and used it to compare infant and adult cortical shape characteristics...
- Cellular and network mechanisms of spike-wave seizuresHal Blumenfeld
Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520 8018, USA
Epilepsia 46:21-33. 2005..It is hoped that improved understanding of the heterogeneous defects and selective brain regions involved will ultimately lead to more effective treatments for spike-wave seizures...
- Images of desire: food-craving activation during fMRIMarcia Levin Pelchat
Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
Neuroimage 23:1486-93. 2004..Craving-related changes in fMRI signal were identified in the hippocampus, insula, and caudate, three areas reported to be involved in drug craving. Thus, this work supports the common substrate hypothesis for food and drug cravings...
- Intrinsic epileptogenicity in polymicrogyric cortex suggested by EEG-fMRI BOLD responsesE Kobayashi
Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada
Neurology 64:1263-6. 2005..Sixteen of 18 studies showed responses, with maximum activation involving the lesion in 61.5%, but often limited to a small fraction of that lesion, suggesting intrinsic epileptogenicity in small areas of the PMG cortex...
- Overlap and interdigitation of cortical and thalamic afferents to dorsocentral striatum in the ratJ L Cheatwood
Department of Physiological Sciences and McKnight Brain Institute, University of Florida, Gainesville, FL 32610, USA
Brain Res 1036:90-100. 2005..These results extend previous findings that DCS receives input from diverse cortical areas and thalamic nuclei which are themselves interconnected...
- Temporal lobe activations of "feeling-of-knowing" induced by face-name associationsHideyuki Kikyo
Department of Physiology, The University of Tokyo School of Medicine, Bunkyo ku, Tokyo 113 0033, Japan
Neuroimage 23:1348-57. 2004....
- To act or not to act. Neural correlates of executive control of learned motor behaviorFriedhelm Hummel
Cortical Physiology Research Group, Department of Neurology, Hertie Institute for Clinical Brain Research, , , Germany
Neuroimage 23:1391-401. 2004....
- Viewing facial expressions of pain engages cortical areas involved in the direct experience of painMatthew Botvinick
Department of Psychiatry, University of Pennsylvania, PA 19104 6241, USA
Neuroimage 25:312-9. 2005..In addition, they lend support to the idea that common neural substrates are involved in representing one's own and others' affective states...
- Neuromagnetic localization of rhythmic activity in the human brain: a comparison of three methodsM Liljestrom
Brain Research Unit, Low Temperature Laboratory, Helsinki University of Technology, P O BOX 2200, FIN 02015 HUT, Espoo, Finland
Neuroimage 25:734-45. 2005..MCE(FD) provides simultaneous localization of sources and was found to give a good overview of the data. With DICS, it was possible to separate close-by sources that were not retrieved by the other two methods...
- Neuronal correlates of consistency and frequency effects on Chinese character naming: an event-related fMRI studyChia-Ying Lee
The Institute of Linguistics, Academia Sinica, Taipei, Taiwan
Neuroimage 23:1235-45. 2004....
- Spatiotemporal brain dynamics in response to muscle stimulationDavid M Niddam
Center for Neuroscience, National Yang-Ming University, Taipei, Taiwan
Neuroimage 25:942-51. 2005..The two streams might on one hand involve sensory discrimination via SI and SII and on the other hand integration of sensory feedback for further motor processing via MI, lateral PM area, and caudal CMA...
- Estimation of the cortical functional connectivity with the multimodal integration of high-resolution EEG and fMRI data by directed transfer functionF Babiloni
Department of Human Physiology and Pharmacology, University La Sapienza, Rome, Italy
Neuroimage 24:118-31. 2005..several types of brain imaging device are available to provide images of the functional activity of the cerebral cortex based on hemodynamic, metabolic, or electromagnetic measurements...
- Cortical/subcortical BOLD changes associated with epileptic discharges: an EEG-fMRI study at 3 TPaolo Federico
Brain Research Institute, Heidelberg West, Victoria, Australia
Neurology 64:1125-30. 2005..The results suggest that EEG-fMRI studies might help elucidate the mechanisms of epileptic discharges in humans...
- Disturbance in the neural circuitry underlying positive emotional processing in post-traumatic stress disorder (PTSD). An fMRI studyAlexander Jatzko
Central Institute of Mental Health (ZI) NMR-Research, 122120, 68072, Mannheim, Germany
Eur Arch Psychiatry Clin Neurosci 256:112-4. 2006..This pilot study is the first to reveal alterations in the processing of positive emotions in PTSD possibly reflecting a neuronal correlate of the symptom of emotional numbness in PTSD...
- Large-scale neural models and dynamic causal modellingLucy Lee
Wellcome Department of Imaging Neuroscience, 12 Queen Square, London WC1N 3BG, UK
Neuroimage 30:1243-54. 2006..Specifically, Bayesian model comparison confirms the validity of DCM in relation to a well-characterised and comprehensive neuronal model...
- Neural representation of language: activation versus long-range connectivityRiitta Salmelin
Brain Research Unit, Low Temperature Laboratory, Helsinki University of Technology, PO Box 2200, FIN 02015 HUT, Finland
Trends Cogn Sci 10:519-25. 2006..Analysis of long-range connectivity might clarify and expand the view provided by traditional neurophysiological and hemodynamic activation studies. Here, we use silent reading as the example process...
- Evidence for acquired pregenual anterior cingulate gray matter loss from a twin study of combat-related posttraumatic stress disorderKiyoto Kasai
Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Biol Psychiatry 63:550-6. 2008..We employed a case-control design in monozygotic twin pairs discordant for combat exposure to address the preexisting versus acquired origin of brain morphometric abnormalities in PTSD...
- Neuronal correlates of obsessions in the caudate nucleusDominique Guehl
Department of Clinical Neurophysiology, CHU de Bordeaux, Place Amelie Rabat Leon, Centre National de Recherche Scientifique Unité Mixte de Recherche 5543, Universite Victor Segalen, Bordeaux, France
Biol Psychiatry 63:557-62. 2008..We tested the hypothesis that obsessions or compulsions might be associated with particular features of neuronal activity in the CN of OCD patients...
- Exploring cortical subplate evolution using magnetic resonance imaging of the fetal brainL Perkins
Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College, Hammersmith Campus, London, UK
Dev Neurosci 30:211-20. 2008..The disappearance of the subplate was regional, involuting most rapidly in the parietal lobe and remaining prominent in the anterior temporal lobe up to 35 weeks. x..
- Tonotopic control of auditory thalamus frequency tuning by reticular thalamic neuronsNathalie Cotillon-Williams
Laboratoire de Neurobiologie de l Apprentissage, de la Memoire et de la Communication, UMR 8620 CNRS, Universite Paris Sud, Batiment 446, Orsay, France
J Neurophysiol 99:1137-51. 2008..nucleus (TRN) can potentially exert strong control over transmission of information through thalamus to the cerebral cortex. Anatomical studies have shown that the reticulo-thalamic connections are spatially organized in the visual, ..
- Associative image analysis: a method for automated quantification of 3D multi-parameter images of brain tissueChristopher S Bjornsson
Center for Neural Communication Technology, New York State Department of Health, Wadsworth Center, Albany, NY 12201 0509, USA
J Neurosci Methods 170:165-78. 2008..Its output is a detailed XML file containing measurements that may be used for diverse quantitative hypothesis-driven and exploratory studies of the central nervous system...
- Characterization of flexible ECoG electrode arrays for chronic recording in awake ratsJohn D Yeager
School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA
J Neurosci Methods 173:279-85. 2008....
- The empathic brain: how, when and why?Frederique de Vignemont
Institut des Sciences Cognitives, 67 Boulevard Pinel, 69675 Bron Cedex, France
Trends Cogn Sci 10:435-41. 2006..Its social role is to serve as the origin of the motivation for cooperative and prosocial behavior, as well as help for effective social communication...
- A stereotaxic MRI template set for the rat brain with tissue class distribution maps and co-registered anatomical atlas: application to pharmacological MRIAdam J Schwarz
Department of Neuroimaging, Psychiatry Centre of Excellence in Drug Discovery, GlaxoSmithKline Medicines Research Centre, Via Fleming 4, 37135 Verona, Italy
Neuroimage 32:538-50. 2006..These developments allow a closer alignment of pre-clinical and clinical analysis techniques...
- Distributed BOLD-response in association cortex vector state space predicts reaction time during selective attentionFrancesco Musso
Laboratory of Molecular Neuroimaging and Electrophysiology, Department of Psychiatry, Johannes Gutenberg-University Hospital, Untere Zahlbacherstr. 8, 55131 Mainz, Germany
Neuroimage 29:1311-8. 2006....
- Frequency flows and the time-frequency dynamics of multivariate phase synchronization in brain signalsDavid Rudrauf
LENA, MEG EEG Center Pitié Salpêtrière, CNRS UPR 640, Universite Pierre et Marie Curie, 47 bd de l Hopital, 75651 Paris Cedex 13, France
Neuroimage 31:209-27. 2006....
- Processing stages underlying word recognition in the anteroventral temporal lobeEric Halgren
Multimodal Imaging Laboratory, Department of Radiology, University of California at San Diego, La Jolla, CA 92093 0841, USA
Neuroimage 30:1401-13. 2006....
- Dynamic causal modelling of evoked responses in EEG/MEG with lead field parameterizationStefan J Kiebel
Wellcome Department of Imaging Neuroscience, Functional Imaging Laboratory, 12 Queen Square, London WC1N 3BG, UK
Neuroimage 30:1273-84. 2006..Using synthetic and real data, we show that this approach furnishes accurate and robust conditional estimates of coupling among sources and their orientations...
- Assessing and improving the spatial accuracy in MEG source localization by depth-weighted minimum-norm estimatesFa Hsuan Lin
MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Building 149 13th St Charlestown, MA 02129, USA
Neuroimage 31:160-71. 2006..The application of depth weighting to auditory and somatosensory experimental data illustrated the beneficial effect of depth weighting on the accuracy of spatiotemporal mapping of neuronal sources...
- Segregation of visceral and somatosensory afferents: an fMRI and cytoarchitectonic mapping studySimon B Eickhoff
Institut for Medizin, Research Centre Julich, Germany
Neuroimage 31:1004-14. 2006..Rather, they evoked activation at a more anterior location on the precentral operculum. These results demonstrate a functionally and anatomically distinct processing of somatosensory and visceral afferents in the human cerebral cortex.
- Neurobehavioral profiles during the acute phase of ethanol withdrawal in adolescent and adult Sprague-Dawley ratsCraig J Slawecki
The Scripps Research Institute, Molecular and Integrative Neuroscience Department, La Jolla, CA 92037, USA
Behav Brain Res 170:41-51. 2006..Adolescent and adult rats show differential sensitivity to many of the effects of ethanol...
- BOLD correlates of EMG spectral density in cortical myoclonus: description of method and case reportMark P Richardson
Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, UK
Neuroimage 32:558-65. 2006....
- Testing anatomically specified hypotheses in functional imaging using cytoarchitectonic mapsSimon B Eickhoff
Institut fur Medizin, Forschungszentrum Julich, Julich, Germany
Neuroimage 32:570-82. 2006..In combination with thresholding based on the Gaussian random field theory, these ROIs can then be applied to test anatomically specified hypotheses in functional neuroimaging studies...
- Testing for nested oscillationW D Penny
Wellcome Trust Centre for Neuroimaging, University College, London, UK
J Neurosci Methods 174:50-61. 2008..Our overall conclusion is that the GLM measure is the best all-round approach for detecting nested oscillation...
- Cerebral perfusion changes in mesial temporal lobe epilepsy: SPM analysis of ictal and interictal SPECTWoo Suk Tae
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 135-710, Republic of Korea
Neuroimage 24:101-10. 2005..In summary, the cerebral perfusion patterns of mTLE suggest interictal hypofunction and ictal activation of the cortico-thalamo-hippocampal-insular network and ictal hypoperfusion of the anterior frontal cortex...
- Relating neuronal dynamics for auditory object processing to neuroimaging activity: a computational modeling and an fMRI studyF T Husain
Brain Imaging and Modeling Section, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892, USA
Neuroimage 21:1701-20. 2004We investigated the neural basis of auditory object processing in the cerebral cortex by combining neural modeling and functional neuroimaging...
- Basal Ganglia and Higher Cortical FunctionPeter L Strick; Fiscal Year: 2010..We and others have argued that abnormal activity in BG loops with the cerebral cortex could lead not only to motor disorders, but also to the behavioral symptoms associated with neuropsychiatric ..
- Cortical connections with the limbic territory of the basal gangliaMichelle Morrow; Fiscal Year: 2007..We and others have argued that abnormal activity in BG loops with the cerebral cortex could lead not only to motor disorders, but also to non-motor symptoms like those associated with Obsessive-..
- Inhibitory Interneurons in Tourette SyndromeFlora M Vaccarino; Fiscal Year: 2010..The cerebral cortex-basal ganglia circuitry regulates motor habits and goal-directed behavior...
- INTERACTION OF THE ESTROGEN RECEPTOR WITH DNAANN NARDULLI; Fiscal Year: 2010..thioredoxin reductase (TrxR), protein disulfide isomerase (PDI), and apurinic endonuclease 1 (APE1) in the cerebral cortex of C57BL/6 mice, (2) define whether estrogens and/or progestins alter the expression of oxidative stress ..
- Molecular Control of Progenitor Cell Polarity and Cortical NeurogenesisSong Hai Shi; Fiscal Year: 2010Proper formation of the cerebral cortex depends on an orderly production of a large number of neurons during embryonic development...
- Basal Ganglia and Higher Cortical FunctionPETER STRICK; Fiscal Year: 2009..We and others have argued that abnormal activity in BG loops with the cerebral cortex could lead not only to motor disorders, but also to the behavioral symptoms associated with neuropsychiatric ..
- Structural determinants of DTI observations in developing cortex and white matterChristopher D Kroenke; Fiscal Year: 2010..Based on preliminary observations of changes in both WM and cerebral cortex FA in neonatally enucleated ferrets, we hypothesize that changes in WM FA arise from abnormalities of myelin/..
- Connexins in Neuronal and Glial Gap Junctions in the Central Nervous SystemJohn E Rash; Fiscal Year: 2010..throughout the complex circuitry of the mouse brain, to make detailed measurements of "mini" gap junctions in cerebral cortex and hippocampus of both mouse and human brain, and to identify the neuronal subtypes linked by "mini" gap ..
- Roles of Gsh1 & 2 genes in telencephalic neurogenesisKenneth Campbell; Fiscal Year: 2006..Two of the major telencephalic regions controlling these processes are the cerebral cortex and the striatum (also known as the caudate-putamen)...
- Correlation of Functional and Structural Units in Cerebral CortexNoam Harel; Fiscal Year: 2010Correlation of Functional and Structural Units in Cerebral Cortex This proposal is an expansion of our earlier NIH R21 project that explored the spatial relationship between functional magnetic resonance imaging (fMRI) signals and the ..
- Correlation of Functional and Structural Units in Cerebral CortexNoam Harel; Fiscal Year: 2009Correlation of Functional and Structural Units in Cerebral Cortex This proposal is an expansion of our earlier NIH R21 project that explored the spatial relationship between functional magnetic resonance imaging (fMRI) signals and the ..
- MECHANISMS OF MOTOR RECOVERY AFTER SUBTOTAL BRAIN INJURYRobert J Morecraft; Fiscal Year: 2010Stroke and traumatic brain injury often involve the cerebral cortex and are leading causes of functional disability collectively affecting greater than 2 million people per year in the United States...
- Basal Ganglia, Cerebellum, and Higher Cortical FunctionPETER STRICK; Fiscal Year: 2007..In contrast, the basal ganglia and cerebellum receive input from multiple areas of the cerebral cortex located in the frontal, parietal, and temporal lobes...
- Basal Ganglia, Cerebellum, and Higher Cortical FunctionPETER STRICK; Fiscal Year: 2003..In contrast, the basal ganglia and cerebellum receive input from multiple areas of the cerebral cortex located in the frontal, parietal, and temporal lobes...
- Inhibitory Interneurons in Tourette SyndromeFlora Vaccarino; Fiscal Year: 2007..The cerebral cortex-basal ganglia circuitry regulates motor habits and goal-directed behavior...
- Inhibitory Interneurons in Tourette SyndromeFlora Vaccarino; Fiscal Year: 2009..The cerebral cortex-basal ganglia circuitry regulates motor habits and goal-directed behavior...
- FIBROBLAST GROWTH FACTOR CEREBRAL CORTICAL DEVELOPMENTFlora Vaccarino; Fiscal Year: 2002The size of the cerebral cortex increases during mammalian evolution, underlying an increased complexity of cognitive operations and specialization of functions...
- In Vivo Imaging of Neuronal Plasticity in Mouse Visual CortexElly Nedivi; Fiscal Year: 2010..provide a baseline for future testing of molecules with therapeutic potential for promoting plasticity in the cerebral cortex. Such molecules may be used to compensate for insults or deterioration at multiple levels of the visual ..
- In Vivo Imaging of Neuronal Plasticity in Mouse Visual CortexElly Nedivi; Fiscal Year: 2011..provide a baseline for future testing of molecules with therapeutic potential for promoting plasticity in the cerebral cortex. Such molecules may be used to compensate for insults or deterioration at multiple levels of the visual ..
- Morphogenesis and function of the cerebral cortexFlora M Vaccarino; Fiscal Year: 2010..This proposal investigates how growth factors of the FGF family establish the primary structure of the cerebral cortex by controlling the genesis of cortical projection neurons from SVZ precursors...
- Sentinel cells that report neural and neurovascular signalingDavid Kleinfeld; Fiscal Year: 2007..addiction may be considerably increased if we know how neurotransmitter levels vary in select regions of cerebral cortex. In particular, it is believed that using addictive drug alters attentional processing mediated by ..
- Molecular Control of Progenitor Cell Polarity and Cortical NeurogenesisSong Hai Shi; Fiscal Year: 2009Proper formation of the cerebral cortex depends on an orderly production of a large number of neurons during embryonic development...
- Radial Glial Development And DifferentiationEva S Anton; Fiscal Year: 2010Polarized radial glial cells provide a template for the formation of cerebral cortex. Initially, they function as a source of new neurons and provide a permissive and instructive scaffold for neuronal migration...
- NEURAL GENE EXPRESSION IN SLEEP DEPRIVATION AND RECOVERYThomas S Kilduff; Fiscal Year: 2010..During the previous funding period, we identified a population of cells in the cerebral cortex that express the neuronal nitric oxide synthase (nNos) within which the transcription factor Fos is expressed ..
- RECONSTRUCTIONS AND REPRESENTATIONS OF CEREBRAL CORTEXDavid C Van Essen; Fiscal Year: 2010..Much of this information pertains to the cerebral cortex and cerebellar cortex, the dominant structures of the human brain...
- Molecular Mechanisms of Cerebral Cortical PatterningElizabeth Grove; Fiscal Year: 2005The broad goal of this research is to identify the mechanisms that generate the area map of the mammalian cerebral cortex. Using the innovative method of in utero electroporation in living mouse embryos we have found evidence that the ..
- REGULATION IN MAMMALIAN NEURAL PROGENITOR CELLSQiang Lu; Fiscal Year: 2009..the growth and maintenance, differentiation, and migration of neural progenitor cells in the mammalian cerebral cortex. During development, neurons of the cerebral cortex arise from neural progenitor cells in the neuroepithelium,..
- CELL IDENTITY DETERMINATION IN CEREBRAL CORTEXChristopher A Walsh; Fiscal Year: 2010..Proper development of the cerebral cortex is essential for normal cognitive function, and requires the precise completion of a series of developmental ..
- Morphogenesis and function of the cerebral cortexFlora Vaccarino; Fiscal Year: 2007..focus on the role of Fibroblast Growth Factors (Fgf) receptors on the morphogenesis and function of the cerebral cortex, and particularly frontal regions, whose development is disrupted in schizophrenia...