cerebral cortex

Summary

Summary: The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon and folds into gyri. It reaches its highest development in man and is responsible for intellectual faculties and higher mental functions.

Top Publications

  1. pmc Neurophysiological and computational principles of cortical rhythms in cognition
    Xiao Jing Wang
    Department of Neurobiology and Kavli Institute of Neuroscience, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Physiol Rev 90:1195-268. 2010
  2. ncbi The representation of object concepts in the brain
    Alex Martin
    Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, Maryland 20892 1366, USA
    Annu Rev Psychol 58:25-45. 2007
  3. ncbi Human SII and posterior insula differently encode thermal laser stimuli
    Maud Frot
    Institut National de la Santé et de la recherche médicale 342, Bron F 69677, France
    Cereb Cortex 17:610-20. 2007
  4. ncbi Simulation of robustness against lesions of cortical networks
    Marcus Kaiser
    School of Computing Science, University of Newcastle, Claremont Tower, Newcastle upon Tyne NE1 7RU, UK
    Eur J Neurosci 25:3185-92. 2007
  5. pmc Identifying neural drivers with functional MRI: an electrophysiological validation
    Olivier David
    INSERM, U836, Grenoble Institut des Neurosciences, Grenoble, France
    PLoS Biol 6:2683-97. 2008
  6. ncbi Thresholding of statistical maps in functional neuroimaging using the false discovery rate
    Christopher R Genovese
    Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Neuroimage 15:870-8. 2002
  7. ncbi Cortical surface-based analysis. I. Segmentation and surface reconstruction
    A M Dale
    Massachusetts General Hosp Harvard Medical School, Building 149, Charlestown, Massachusetts, 02129, USA
    Neuroimage 9:179-94. 1999
  8. doi How do you feel--now? The anterior insula and human awareness
    A D Bud Craig
    Atkinson Research Laboratory, Barrow Neurological Institute, Phoenix, Arizona 85013, USA
    Nat Rev Neurosci 10:59-70. 2009
  9. pmc Mapping the structural core of human cerebral cortex
    Patric Hagmann
    Department of Radiology, University Hospital Center and University of Lausanne CHUV, Lausanne, Switzerland
    PLoS Biol 6:e159. 2008
  10. ncbi Automated Talairach atlas labels for functional brain mapping
    J L Lancaster
    Research Imaging Center, University of Texas Health Science Center at San Antonio, 78284, USA
    Hum Brain Mapp 10:120-31. 2000

Detail Information

Publications238 found, 100 shown here

  1. pmc Neurophysiological and computational principles of cortical rhythms in cognition
    Xiao Jing Wang
    Department of Neurobiology and Kavli Institute of Neuroscience, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Physiol Rev 90:1195-268. 2010
    ..This review focuses on oscillations in the cerebral cortex that occur during cognition, in alert behaving conditions...
  2. ncbi The representation of object concepts in the brain
    Alex Martin
    Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, Maryland 20892 1366, USA
    Annu Rev Psychol 58:25-45. 2007
    ..However, some property-based regions seem to show a categorical organization, thus providing evidence consistent with category-based, domain-specific formulations as well...
  3. ncbi Human SII and posterior insula differently encode thermal laser stimuli
    Maud Frot
    Institut National de la Santé et de la recherche médicale 342, Bron F 69677, France
    Cereb Cortex 17:610-20. 2007
    ....
  4. ncbi Simulation of robustness against lesions of cortical networks
    Marcus Kaiser
    School of Computing Science, University of Newcastle, Claremont Tower, Newcastle upon Tyne NE1 7RU, UK
    Eur J Neurosci 25:3185-92. 2007
    ..This informs the understanding of the development of connectivity of the brain networks...
  5. pmc Identifying neural drivers with functional MRI: an electrophysiological validation
    Olivier David
    INSERM, U836, Grenoble Institut des Neurosciences, Grenoble, France
    PLoS Biol 6:2683-97. 2008
    ..As such, it has important implications for future studies on brain connectivity using functional neuroimaging...
  6. ncbi Thresholding of statistical maps in functional neuroimaging using the false discovery rate
    Christopher R Genovese
    Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Neuroimage 15:870-8. 2002
    ..We demonstrate this approach using both simulations and functional magnetic resonance imaging data from two simple experiments...
  7. ncbi Cortical surface-based analysis. I. Segmentation and surface reconstruction
    A M Dale
    Massachusetts General Hosp Harvard Medical School, Building 149, Charlestown, Massachusetts, 02129, USA
    Neuroimage 9:179-94. 1999
    Several properties of the cerebral cortex, including its columnar and laminar organization, as well as the topographic organization of cortical areas, can only be properly understood in the context of the intrinsic two-dimensional ..
  8. doi How do you feel--now? The anterior insula and human awareness
    A D Bud Craig
    Atkinson Research Laboratory, Barrow Neurological Institute, Phoenix, Arizona 85013, USA
    Nat Rev Neurosci 10:59-70. 2009
    ..New findings suggest a fundamental role for the AIC (and the von Economo neurons it contains) in awareness, and thus it needs to be considered as a potential neural correlate of consciousness...
  9. pmc Mapping the structural core of human cerebral cortex
    Patric Hagmann
    Department of Radiology, University Hospital Center and University of Lausanne CHUV, Lausanne, Switzerland
    PLoS Biol 6:e159. 2008
    Structurally segregated and functionally specialized regions of the human cerebral cortex are interconnected by a dense network of cortico-cortical axonal pathways...
  10. ncbi Automated Talairach atlas labels for functional brain mapping
    J L Lancaster
    Research Imaging Center, University of Texas Health Science Center at San Antonio, 78284, USA
    Hum Brain Mapp 10:120-31. 2000
    ..Additional suggested applications of the TD system include interactive labeling, anatomical grouping of activation foci, lesion-deficit analysis, and neuroanatomy education...
  11. ncbi A resilient, low-frequency, small-world human brain functional network with highly connected association cortical hubs
    Sophie Achard
    Wolfson Brain Imaging Centre, University of Cambridge, Department of Psychiatry, Addenbrooke s Hospital, Cambridge CB2 2QQ, United Kingdom
    J Neurosci 26:63-72. 2006
    ..Because the major hubs of this network are critical for cognition, its slow dynamics could provide a physiological substrate for segregated and distributed information processing...
  12. ncbi The cortical organization of speech processing
    Gregory Hickok
    Department of Cognitive Sciences and The Center for Cognitive Neuroscience, University of California, Irvine, California 92697 5100, USA
    Nat Rev Neurosci 8:393-402. 2007
    ....
  13. pmc A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks
    Devarajan Sridharan
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 105:12569-74. 2008
    ..Our findings have important implications for a unified view of network mechanisms underlying both exogenous and endogenous cognitive control...
  14. pmc Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease
    Randy L Buckner
    Department of Psychology and Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA
    J Neurosci 29:1860-73. 2009
    ..To identify regions of high connectivity in the human cerebral cortex, we applied a computationally efficient approach to map the degree of intrinsic functional connectivity ..
  15. pmc Predicting human resting-state functional connectivity from structural connectivity
    C J Honey
    Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, USA
    Proc Natl Acad Sci U S A 106:2035-40. 2009
    In the cerebral cortex, the activity levels of neuronal populations are continuously fluctuating...
  16. ncbi Empathy for pain involves the affective but not sensory components of pain
    Tania Singer
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College of London, 12 Queen Square, WC1N 3AR London, UK
    Science 303:1157-62. 2004
    ..We conclude that only that part of the pain network associated with its affective qualities, but not its sensory qualities, mediates empathy...
  17. ncbi An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest
    Rahul S Desikan
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, W701, Boston, MA 02118, USA
    Neuroimage 31:968-80. 2006
    ..the validity and reliability of an automated labeling system that we have developed for subdividing the human cerebral cortex on magnetic resonance images into gyral based regions of interest (ROIs)...
  18. ncbi How do you feel? Interoception: the sense of the physiological condition of the body
    A D Craig
    Nat Rev Neurosci 3:655-66. 2002
    ..This system constitutes a representation of 'the material me', and might provide a foundation for subjective feelings, emotion and self-awareness...
  19. ncbi Control of goal-directed and stimulus-driven attention in the brain
    Maurizio Corbetta
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Nat Rev Neurosci 3:201-15. 2002
    ..This ventral frontoparietal network works as a 'circuit breaker' for the dorsal system, directing attention to salient events. Both attentional systems interact during normal vision, and both are disrupted in unilateral spatial neglect...
  20. pmc The organization of the human cerebral cortex estimated by intrinsic functional connectivity
    B T Thomas Yeo
    Harvard University, Department of Psychology, Center for Brain Science, Cambridge, MA 02138, USA
    J Neurophysiol 106:1125-65. 2011
    Information processing in the cerebral cortex involves interactions among distributed areas. Anatomical connectivity suggests that certain areas form local hierarchical relations such as within the visual system...
  21. ncbi Frequencies contributing to functional connectivity in the cerebral cortex in "resting-state" data
    D Cordes
    Department of Medical Physics, University of Wisconsin at Madison, 1300 University Ave, 1530 MSC, Madison, WI 53706, USA
    AJNR Am J Neuroradiol 22:1326-33. 2001
    ..In functionally connected regions, these low frequencies are characterized by a high degree of temporal coherence...
  22. ncbi The small world of the cerebral cortex
    Olaf Sporns
    Department of Psychology, Indiana University, Bloomington 47405, USA
    Neuroinformatics 2:145-62. 2004
    While much information is available on the structural connectivity of the cerebral cortex, especially in the primate, the main organizational principles of the connection patterns linking brain areas, columns and individual cells have ..
  23. ncbi Hemispheric asymmetry reduction in older adults: the HAROLD model
    Roberto Cabeza
    Center for Cognitive Neuroscience, Duke University, Durham, North Carolina 27708, USA
    Psychol Aging 17:85-100. 2002
    ..They may have a cognitive or neural origin, and they may reflect regional or network mechanisms. The HAROLD model is a cognitive neuroscience model that integrates ideas and findings from psychology and neuroscience of aging...
  24. pmc Distinct brain networks for adaptive and stable task control in humans
    Nico U F Dosenbach
    Department of Radiology, Washington University, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 104:11073-8. 2007
    ..These two independent networks appear to operate on different time scales and affect downstream processing via dissociable mechanisms...
  25. pmc Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex
    Giorgio A Ascoli
    Molecular Neuroscience Department and Center for Neural Informatics, Structures, and Plasticity, Krasnow Institute for Advanced Study, George Mason University, MS2A1, 4400 University Drive, Fairfax, Virginia 22030, USA
    Nat Rev Neurosci 9:557-68. 2008
    ..of terms to describe the anatomical, physiological and molecular features of GABAergic interneurons of the cerebral cortex. The resulting terminology might provide a stepping stone towards a future classification of these complex ..
  26. doi Two systems of resting state connectivity between the insula and cingulate cortex
    Keri S Taylor
    Division of Brain, Imaging and Behavior Systems Neuroscience, Toronto Western Research Institute, University Health Network, Toronto, Canada
    Hum Brain Mapp 30:2731-45. 2009
    ....
  27. ncbi Automatically parcellating the human cerebral cortex
    Bruce Fischl
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, MGH MIT Harvard Medical School, Massachusetts General Hospital, 13th Street, Charlestown, MA 02129, USA
    Cereb Cortex 14:11-22. 2004
    ..Examples are given from two different training sets generated using different neuroanatomical conventions, illustrating the flexibility of the algorithm. The technique is shown to be comparable in accuracy to manual labeling...
  28. pmc Identification and classification of hubs in brain networks
    Olaf Sporns
    Department of Psychological and Brain Sciences and Program in Cognitive Science, Indiana University, Bloomington, Indiana, United States of America
    PLoS ONE 2:e1049. 2007
    Brain regions in the mammalian cerebral cortex are linked by a complex network of fiber bundles...
  29. ncbi Neuronal oscillations in cortical networks
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, State University of New Jersey, Newark, NJ 07102, USA
    Science 304:1926-9. 2004
    ....
  30. ncbi Different frequencies for different scales of cortical integration: from local gamma to long range alpha/theta synchronization
    A von Stein
    Institute of Neuroinformatics, ETH University Zurich, Winterthurerstr 190, CH 8057, Zurich, Switzerland
    Int J Psychophysiol 38:301-13. 2000
    ..e. for top-down processing. We propose that large scale integration is performed by synchronization among neurons and neuronal assemblies evolving in different frequency ranges...
  31. pmc Mapping anatomical connectivity patterns of human cerebral cortex using in vivo diffusion tensor imaging tractography
    Gaolang Gong
    Department of Biomedical Engineering, 1098 Research Transition Facility, University of Alberta, Edmonton, Alberta, Canada
    Cereb Cortex 19:524-36. 2009
    ..to construct a macroscale anatomical network capturing the underlying common connectivity pattern of human cerebral cortex in a large sample of subjects (80 young adults) and further quantitatively analyzed its topological ..
  32. ncbi The mismatch negativity (MMN) in basic research of central auditory processing: a review
    R Naatanen
    Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Helsinki, Finland
    Clin Neurophysiol 118:2544-90. 2007
    ..In addition, the MMN enables one to establish the brain processes underlying the initiation of attention switch to, conscious perception of, sound change in an unattended stimulus stream...
  33. ncbi Neural mechanisms of autonomic, affective, and cognitive integration
    Hugo D Critchley
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London UCL Autonomic Unit, Institute of Cognitive Neuroscience, UCL, Queen Square, London WC1N 3BG, United Kingdom
    J Comp Neurol 493:154-66. 2005
    ..Generation of visceral autonomic correlates of control reinforce experiential engagement in simulatory models and underpin concepts such as somatic markers to bridge the dualistic divide...
  34. ncbi Interoception: the sense of the physiological condition of the body
    A D Craig
    Atkinson Pain Research Laboratory, Division of Neurosurgery, Barrow Neurological Institute, Phoenix, AZ 85013, USA
    Curr Opin Neurobiol 13:500-5. 2003
    ....
  35. ncbi Breakdown of cortical effective connectivity during sleep
    Marcello Massimini
    Department of Psychiatry, University of Wisconsin, Madison, 6001 Research Park Boulevard, Madison, WI 53719, USA
    Science 309:2228-32. 2005
    ..Thus, the fading of consciousness during certain stages of sleep may be related to a breakdown in cortical effective connectivity...
  36. ncbi Reliability of MRI-derived measurements of human cerebral cortical thickness: the effects of field strength, scanner upgrade and manufacturer
    Xiao Han
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
    Neuroimage 32:180-94. 2006
    In vivo MRI-derived measurements of human cerebral cortex thickness are providing novel insights into normal and abnormal neuroanatomy, but little is known about their reliability...
  37. pmc A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex
    Hiroki Taniguchi
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    Neuron 71:995-1013. 2011
    A key obstacle to understanding neural circuits in the cerebral cortex is that of unraveling the diversity of GABAergic interneurons...
  38. ncbi Probabilistic decision making by slow reverberation in cortical circuits
    Xiao Jing Wang
    Volen Center for Complex Systems, Brandeis University, Waltham, MA 02254, USA
    Neuron 36:955-68. 2002
    ....
  39. pmc A core system for the implementation of task sets
    Nico U F Dosenbach
    Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 50:799-812. 2006
    ..Prefrontal regions commonly related to task control carried task-set signals in a smaller subset of tasks and lacked convergence across signal types...
  40. doi A link between the systems: functional differentiation and integration within the human insula revealed by meta-analysis
    Florian Kurth
    C and O Vogt Institute of Brain Research, University Düsseldorf, Dusseldorf, Germany
    Brain Struct Funct 214:519-34. 2010
    ....
  41. ncbi The neural bases of momentary lapses in attention
    D H Weissman
    Center for Cognitive Neuroscience and Department of Psychiatry, Duke University, Durham, North Carolina 27708, USA
    Nat Neurosci 9:971-8. 2006
    ..Our findings provide a new, system-wide understanding of the patterns of brain activity that are associated with brief attentional lapses, which informs both theoretical and clinical models of goal-directed behavior...
  42. pmc The neural code between neocortical pyramidal neurons depends on neurotransmitter release probability
    M V Tsodyks
    Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel
    Proc Natl Acad Sci U S A 94:719-23. 1997
    ..We conclude that by setting the rate of synaptic depression, release probability is an important factor in determining the neural code...
  43. ncbi Mapping cortical change across the human life span
    Elizabeth R Sowell
    University of California at Los Angeles, Laboratory of Neuro Imaging, Department of Neurology, 710 Westwood Plaza, Los Angeles, California 90095, USA
    Nat Neurosci 6:309-15. 2003
    ..Our findings also indicate that the posterior temporal cortices, primarily in the left hemisphere, which typically support language functions, have a more protracted course of maturation than any other cortical region...
  44. doi Evidence for segregated and integrative connectivity patterns in the human Basal Ganglia
    Bogdan Draganski
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, UCL, London WC1N 3BG, United Kingdom
    J Neurosci 28:7143-52. 2008
    ..We believe that this method can be used to examine pathophysiological concepts in a number of basal ganglia-related disorders...
  45. ncbi Circuitry and functional aspects of the insular lobe in primates including humans
    J R Augustine
    Department of Cell Biology and Neuroscience, University of South Carolina School of Medicine, Columbia 29208, USA
    Brain Res Brain Res Rev 22:229-44. 1996
    ..Recent studies have expanded the role of the insula as a somatosensory area, emphasizing its multifaceted, sensory role. The idea of the insula as limbic integration cortex has been affirmed and its role in Alzheimer's disease suggested...
  46. doi A common role of insula in feelings, empathy and uncertainty
    Tania Singer
    Laboratory for Social and Neural Systems Research, University of Zurich, Switzerland
    Trends Cogn Sci 13:334-40. 2009
    ..Such mechanisms could facilitate affective learning and regulation of body homeostasis, and could also guide decision making in complex and uncertain environments...
  47. ncbi Cortical midline structures and the self
    Georg Northoff
    Laboratory for Magnetic Brain Stimulation, Division of Behavioral Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Trends Cogn Sci 8:102-7. 2004
    ..All of these subfunctions are related to distinct regions within the CMS. This relationship between self-referential processing and CMS might provide novel insight into the neural correlates underlying the constitution of the self...
  48. ncbi An insular view of anxiety
    Martin P Paulus
    Department of Psychiatry, University of California, San Diego, La Jolla, California 92037, USA
    Biol Psychiatry 60:383-7. 2006
    ....
  49. doi What does the retrosplenial cortex do?
    Seralynne D Vann
    School of Psychology, Cardiff University, Tower Building, Park Place, Cardiff, CF10 3AT, UK
    Nat Rev Neurosci 10:792-802. 2009
    ....
  50. ncbi Intellectual ability and cortical development in children and adolescents
    P Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20182, USA
    Nature 440:676-9. 2006
    ..Here we demonstrate that the trajectory of change in the thickness of the cerebral cortex, rather than cortical thickness itself, is most closely related to level of intelligence...
  51. ncbi Regional and progressive thinning of the cortical ribbon in Huntington's disease
    H D Rosas
    Department of Neurology, Massachusetts General Hospital and Harvard Medical School, 02129 4404, USA
    Neurology 58:695-701. 2002
    ....
  52. pmc The dynamic brain: from spiking neurons to neural masses and cortical fields
    Gustavo Deco
    Institucio Catalana de Recerca i Estudis Avancats ICREA, Universitat Pompeu Fabra, Department of Technology, Computational Neuroscience, Barcelona, Spain
    PLoS Comput Biol 4:e1000092. 2008
    ..We argue that elaborating principled and informed models is a prerequisite for grounding empirical neuroscience in a cogent theoretical framework, commensurate with the achievements in the physical sciences...
  53. doi Human insula activation reflects risk prediction errors as well as risk
    Kerstin Preuschoff
    Computation and Neural Systems Program and Division of Humanities and Social Sciences, Caltech, Pasadena, California 91125, USA
    J Neurosci 28:2745-52. 2008
    ..As such, our findings indicate that our understanding of the neural basis of reward anticipation under uncertainty needs to be expanded to include risk prediction...
  54. ncbi Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation
    Micaela Zonta
    Istituto CNR di Neuroscienze and Dipartimento di Scienze Biomediche Sperimentali, Universita di Padova, Viale G Colombo 3, 35121 Padova, Italy
    Nat Neurosci 6:43-50. 2003
    ..Taken together, our findings show that neuron-to-astrocyte signaling is a key mechanism in functional hyperemia...
  55. pmc Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus
    Tigwa H Davis
    Department of Ophthalmology, University of California, San Francisco, San Francisco, California 94143 0730, USA
    J Neurosci 28:4322-30. 2008
    ....
  56. ncbi Geometrically accurate topology-correction of cortical surfaces using nonseparating loops
    Florent Segonne
    CERTIS Laboratory, ENPC, 19 rue Nobel Cité Descartes, Champs sur Marne 77455, France
    IEEE Trans Med Imaging 26:518-29. 2007
    ..Applied to real data, our method provides topological corrections similar to those made by a trained operator...
  57. pmc Spontaneous cortical activity in awake monkeys composed of neuronal avalanches
    Thomas Petermann
    Section on Critical Brain Dynamics, National Institute of Mental Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 106:15921-6. 2009
    Spontaneous neuronal activity is an important property of the cerebral cortex but its spatiotemporal organization and dynamical framework remain poorly understood...
  58. pmc An integrated software suite for surface-based analyses of cerebral cortex
    D C Van Essen
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Am Med Inform Assoc 8:443-59. 2001
    ..describe and illustrate an integrated trio of software programs for carrying out surface-based analyses of cerebral cortex. The first component of this trio, SureFit (Surface Reconstruction by Filtering and Intensity Transformations)..
  59. ncbi Dynamic statistical parametric mapping: combining fMRI and MEG for high-resolution imaging of cortical activity
    A M Dale
    Massachusetts General Hospital Nuclear Magnetic Resonance Center, Charlestown 02129, USA
    Neuron 26:55-67. 2000
    ..Repetition effects were observed in many of the same areas following this initial wave of activation, providing evidence for the involvement of feedback mechanisms in repetition priming...
  60. doi Neurodevelopmental trajectories of the human cerebral cortex
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Neurosci 28:3586-94. 2008
    Understanding the organization of the cerebral cortex remains a central focus of neuroscience. Cortical maps have relied almost exclusively on the examination of postmortem tissue to construct structural, architectonic maps...
  61. ncbi A Population-Average, Landmark- and Surface-based (PALS) atlas of human cerebral cortex
    David C Van Essen
    Department of Anatomy and Neurobiology, Washington University School of Medicine, 660 S Euclid Ave, Box 8108, St Louis, MO 63110, USA
    Neuroimage 28:635-62. 2005
    This report describes a new electronic atlas of human cerebral cortex that provides a substrate for a wide variety of brain-mapping analyses...
  62. ncbi Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage
    Jessica A Gorski
    Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Colorado 80309, USA
    J Neurosci 22:6309-14. 2002
    ..Structures that are located near the basal ganglia (e.g., the amygdala and endopiriform nuclei) are not uniformly derived from Emx1-expressing cells...
  63. ncbi Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2
    M Trommsdorff
    Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas 75235 9046, USA
    Cell 97:689-701. 1999
    Layering of neurons in the cerebral cortex and cerebellum requires Reelin, an extracellular matrix protein, and mammalian Disabled (mDab1), a cytosolic protein that activates tyrosine kinases...
  64. ncbi Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
    Roberta Magliozzi
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Brain 130:1089-104. 2007
    ..disability and death and more pronounced demyelination, microglia activation and loss of neurites in the cerebral cortex. Cortical demyelination in these SPMS cases was also more severe than in PPMS cases...
  65. ncbi Automated manifold surgery: constructing geometrically accurate and topologically correct models of the human cerebral cortex
    B Fischl
    Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Harvard Medical School, Charlestown 02129, USA
    IEEE Trans Med Imaging 20:70-80. 2001
    Highly accurate surface models of the cerebral cortex are becoming increasingly important as tools in the investigation of the functional organization of the human brain...
  66. ncbi Consciousness and complexity
    G Tononi
    Neurosciences Institute, 10640 John J Hopkins Drive, San Diego, CA 92121, USA
    Science 282:1846-51. 1998
    ..Applying measures of neural integration and complexity, together with an analysis of extensive neurological data, leads to a testable proposal-the dynamic core hypothesis-about the properties of the neural substrate of consciousness...
  67. ncbi Reelin and brain development
    Fadel Tissir
    Developmental Genetics Unit, Universite Catholique de Louvain, UCL 7382, 73 Avenue E Mounier, B1200 Brussels, Belgium
    Nat Rev Neurosci 4:496-505. 2003
  68. pmc In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2
    Benjamin R Arenkiel
    Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710, USA
    Neuron 54:205-18. 2007
    ..Using focal illumination of the cerebral cortex and olfactory bulb, we demonstrate a highly reproducible, light-dependent activation of neurons and precise ..
  69. ncbi The sleep slow oscillation as a traveling wave
    Marcello Massimini
    Department of Psychiatry, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
    J Neurosci 24:6862-70. 2004
    ..The orderly propagation of correlated activity along connected pathways may play a role in spike timing-dependent synaptic plasticity during sleep...
  70. ncbi Cortical networks for working memory and executive functions sustain the conscious resting state in man
    B Mazoyer
    Groupe d'Imagerie Neurofonctionnelle, UMR6095, CNRS, LEA, , , Paris, France
    Brain Res Bull 54:287-98. 2001
    ....
  71. ncbi The neuroscience of tinnitus
    Jos J Eggermont
    Department of Physiology and Biophysics, and Department of Psychology, University of Calgary, Alberta, Canada T2N 1N4
    Trends Neurosci 27:676-82. 2004
    ..Downregulation of intracortical inhibition induced by damage to the cochlea or to auditory projection pathways highlights neural processes that underlie the sensation of phantom sound...
  72. doi Parvalbumin neurons and gamma rhythms enhance cortical circuit performance
    Vikaas S Sohal
    Department of Bioengineering, Stanford University, Stanford, California 94305, USA
    Nature 459:698-702. 2009
    ....
  73. ncbi Three-dimensional probabilistic anatomical cranio-cerebral correlation via the international 10-20 system oriented for transcranial functional brain mapping
    Masako Okamoto
    National Food Research Institute, Tsukuba 305 8642, Japan
    Neuroimage 21:99-111. 2004
    ..This study provided an initial step toward establishing a three-dimensional probabilistic anatomical platform that enables intra- and intermodal comparisons of NIRS and TMS brain imaging data...
  74. ncbi Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases
    Stephen C Noctor
    Department of Neurology, Columbia University College of Physicians and Surgeons, 630 W 168th Street, New York, New York 10032, USA
    Nat Neurosci 7:136-44. 2004
    ..division and migration are crucial to transform the neuroepithelium of the embryonic forebrain into the adult cerebral cortex. Using time-lapse imaging of clonal cells in rat cortex over several generations, we show here that neurons ..
  75. ncbi Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
    T Nakagawa
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 403:98-103. 2000
    ..Thus, caspase-12 mediates an ER-specific apoptosis pathway and may contribute to amyloid-beta neurotoxicity...
  76. ncbi Analysis of functional image analysis contest (FIAC) data with brainvoyager QX: From single-subject to cortically aligned group general linear model analysis and self-organizing group independent component analysis
    Rainer Goebel
    Brain Innovation, Maastricht, The Netherlands
    Hum Brain Mapp 27:392-401. 2006
    ..Using spatially and temporally unsmoothed data, this cortex-based analysis revealed comparable results but with a set of spatially more confined group clusters and more differential group region of interest time courses...
  77. ncbi Neural simulation of action: a unifying mechanism for motor cognition
    M Jeannerod
    Institut des Sciences Cognitives, 67 Boulevard Pinel, Bron, 69675, France
    Neuroimage 14:S103-9. 2001
    ..The function of this process of simulation would be not only to shape the motor system in anticipation to execution, but also to provide the self with information on the feasibility and the meaning of potential actions...
  78. doi Neuroanatomy of autism
    David G Amaral
    The M I N D Institute, Department of Psychiatry and Behavioral Sciences, University of California, Davis, 2825 50th Street, Sacramento, CA 95817, USA
    Trends Neurosci 31:137-45. 2008
    ..Defined phenotypes in larger samples of children and well-characterized brain tissue will be necessary for clarification of the neuroanatomy of autism...
  79. pmc A theory of cortical responses
    Karl Friston
    The Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
    Philos Trans R Soc Lond B Biol Sci 360:815-36. 2005
    ..The final focus of this article is on perceptual learning as measured with the MMN and the implications for empirical studies of coupling among cortical areas using evoked sensory responses...
  80. ncbi Neural activity in the human brain relating to uncertainty and arousal during anticipation
    H D Critchley
    Wellcome Department of Cognitive Neurology, 12 Queen Square, Institute of Neurology, University College London, WC1N 3BG, London, United Kingdom
    Neuron 29:537-45. 2001
    ..Our findings highlight distinct contributions of cognitive uncertainty and autonomic arousal to anticipatory neural activity in prefrontal cortex...
  81. ncbi Grouping of brain rhythms in corticothalamic systems
    M Steriade
    Laboratory of Neurophysiology, Laval University, Faculty of Medicine, Quebec, Canada G1K 7P4
    Neuroscience 137:1087-106. 2006
    ....
  82. ncbi Theoretical neuroanatomy: relating anatomical and functional connectivity in graphs and cortical connection matrices
    O Sporns
    The Neurosciences Institute, 10640 John Jay Hopkins Drive, San Diego, CA 92121, USA
    Cereb Cortex 10:127-41. 2000
    Neuroanatomy places critical constraints on the functional connectivity of the cerebral cortex. To analyze these constraints we have examined the relationship between structural features of networks (expressed as graphs) and the patterns ..
  83. ncbi Dynamic I-V curves are reliable predictors of naturalistic pyramidal-neuron voltage traces
    Laurent Badel
    Laboratory of Computational Neuroscience, School of Computer and Communication Sciences and Brain Institute, Lausanne, Switzerland
    J Neurophysiol 99:656-66. 2008
    ..The predictions of the resulting model are in excellent agreement with experimental data and close to the intrinsic neuronal reproducibility to repeated stimuli...
  84. ncbi Increased activation in the right insula during risk-taking decision making is related to harm avoidance and neuroticism
    Martin P Paulus
    Laboratory of Biological Dynamics and Theoretical Medicine, Department of Psychiatry, University of California San Diego, La Jolla, CA 92093 0603, USA
    Neuroimage 19:1439-48. 2003
    ..These results are consistent with the hypothesis that insula activation serves as a critical neural substrate to instantiate aversive somatic markers that guide risk-taking decision-making behavior...
  85. ncbi Mapping directed influence over the brain using Granger causality and fMRI
    Alard Roebroeck
    Department of Cognitive Neuroscience, Faculty of Psychology, University of Maastricht, The Netherlands
    Neuroimage 25:230-42. 2005
    ..The presented exploratory approach of mapping influences between a region of interest and the rest of the brain can form a useful complement to existing models of effective connectivity...
  86. doi GABAergic depolarization of the axon initial segment in cortical principal neurons is caused by the Na-K-2Cl cotransporter NKCC1
    Stanislav Khirug
    Department of Biological and Environmental Sciences, University of Helsinki, FIN 00014 Helsinki, Finland
    J Neurosci 28:4635-9. 2008
    ..Our findings demonstrate that spatially distinct interneuronal inputs can induce postsynaptic voltage responses with different amplitudes and polarities as governed by the subcellular distributions of plasmalemmal chloride transporters...
  87. ncbi Perisomatic inhibition
    Tamas F Freund
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
    Neuron 56:33-42. 2007
    Recent evidence supports the hypothesis of a functional dichotomy of perisomatic inhibition in the cerebral cortex: the parvalbumin- and cholecystokinin-containing basket cells that are specialized to control rhythm (as a clockwork) and "..
  88. ncbi Brain activity varies with modulation of dynamic pitch variance in sentence melody
    Martin Meyer
    Max Planck Institute of Cognitive Neuroscience, Leipzig, Germany
    Brain Lang 89:277-89. 2004
    ..Finally, it appears that brain areas which subserve speech (frontal operculum) and premotor functions (Rolandic operculum) coincidently support the processing of intonation contour in spoken sentence comprehension...
  89. ncbi Psychological and neural mechanisms of the affective dimension of pain
    D D Price
    Department of Oral and Maxillofacial Surgery, University of Florida, Health Science Center, Post Office Box 100416, Gainesville, FL 32610 0416, USA
    Science 288:1769-72. 2000
    ..Both direct and cortico-limbic pathways converge on the same anterior cingulate cortical and subcortical structures whose function may be to establish emotional valence and response priorities...
  90. ncbi Thermosensory activation of insular cortex
    A D Craig
    Division of Neurosurgery, Barrow Neurological Institute, 350 West Thomas Rd, Phoenix, Arizona 85013, USA
    Nat Neurosci 3:184-90. 2000
    ..Notably, perceived thermal intensity was well correlated with activation in the right (ipsilateral) anterior insular and orbitofrontal cortices...
  91. ncbi Excitatory actions of GABA in the cortex
    Allan T Gulledge
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Mills Road, Canberra, ACT 0200, Australia
    Neuron 37:299-309. 2003
    ..Our findings demonstrate that under certain circumstances GABA will have an excitatory role in synaptic integration in the cortex...
  92. ncbi Dopamine regulates the impact of the cerebral cortex on the subthalamic nucleus-globus pallidus network
    P J Magill
    Medical Research Council Anatomical Neuropharmacology Unit, University of Oxford, Mansfield Road, Oxford OX1 3TH, UK
    Neuroscience 106:313-30. 2001
    ..Furthermore, the relative contribution of rate and pattern to aberrant information coding is intimately related to the state of activation of the cerebral cortex.
  93. ncbi Painful stimuli evoke different stimulus-response functions in the amygdala, prefrontal, insula and somatosensory cortex: a single-trial fMRI study
    K Bornhovd
    Cognitive Neuroscience Laboratory, Department of Neurology, Hamburg University Medical School, Germany
    Brain 125:1326-36. 2002
    ..e. 'uncertain' trials), the evoked signal changes were as great as in P3 trials, indicating that the amygdala is involved in coding 'uncertainty', as has been suggested previously in relation to classical conditioning...
  94. ncbi From sensation to cognition
    M M Mesulam
    Department of Neurology, Northwestern University Medical School, Chicago 60611, USA
    Brain 121:1013-52. 1998
    ..the primary sensory, upstream unimodal, downstream unimodal, heteromodal, paralimbic and limbic zones of the cerebral cortex. Connections from one zone to another are reciprocal and allow higher synaptic levels to exert a feedback (..
  95. ncbi Neuronal and glial localization of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter, in human cerebral cortex: with a note on its distribution in monkey cortex
    F Conti
    Institute of Human Physiology, University of Ancona, Italy
    J Comp Neurol 396:51-63. 1998
    ..membrane transporters (GATs) influence the action of GABA, the main inhibitory neurotransmitter in the human cerebral cortex. In this study, the cellular expression of GAT-1, the main cortical GABA transporter, was investigated in the ..
  96. doi An intrinsic mechanism of corticogenesis from embryonic stem cells
    Nicolas Gaspard
    IRIBHM Institute for Interdisciplinary Research, Universite Libre de Bruxelles ULB
    Nature 455:351-7. 2008
    The cerebral cortex develops through the coordinated generation of dozens of neuronal subtypes, but the mechanisms involved remain unclear...
  97. pmc The determination of projection neuron identity in the developing cerebral cortex
    Dino P Leone
    Department of Biology, Stanford University, Stanford, CA 94305, USA
    Curr Opin Neurobiol 18:28-35. 2008
    ..Pyramidal neurons in the mammalian cerebral cortex can be classified into two major classes: corticocortical projection neurons, which are concentrated in the ..
  98. ncbi Faces and objects in macaque cerebral cortex
    Doris Y Tsao
    Athinoula A Martinos Center, Charlestown, Massachusetts 02129, USA
    Nat Neurosci 6:989-95. 2003
    ..Overall, our results suggest that humans and macaques share a similar brain architecture for visual object processing...
  99. ncbi The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells
    Yusuke Hirabayashi
    Institute of Molecular and Cellular Biosciences, University of Tokyo, 1 1 1 Yayoi, Bunkyo ku, Tokyo 113 0032, Japan
    Development 131:2791-801. 2004
    ..These findings may reveal broader and stage-specific physiological roles of Wnt signaling during neural development...
  100. doi Object recognition memory: neurobiological mechanisms of encoding, consolidation and retrieval
    Boyer D Winters
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Neurosci Biobehav Rev 32:1055-70. 2008
    ..Recent studies in rodents have begun to indicate the remarkable complexity of the neural substrates underlying this seemingly simple aspect of declarative memory...
  101. ncbi Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex
    Joshua T Trachtenberg
    Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
    Nature 420:788-94. 2002
    ..Our measurements suggest that sensory experience drives the formation and elimination of synapses and that these changes might underlie adaptive remodelling of neural circuits...

Research Grants85

  1. Basal Ganglia and Higher Cortical Function
    Peter L Strick; Fiscal Year: 2010
    ..We and others have argued that abnormal activity in BG loops with the cerebral cortex could lead not only to motor disorders, but also to the behavioral symptoms associated with neuropsychiatric ..
  2. Cortical connections with the limbic territory of the basal ganglia
    Michelle Morrow; Fiscal Year: 2007
    ..We and others have argued that abnormal activity in BG loops with the cerebral cortex could lead not only to motor disorders, but also to non-motor symptoms like those associated with Obsessive-..
  3. Inhibitory Interneurons in Tourette Syndrome
    Flora M Vaccarino; Fiscal Year: 2010
    ..The cerebral cortex-basal ganglia circuitry regulates motor habits and goal-directed behavior...
  4. INTERACTION OF THE ESTROGEN RECEPTOR WITH DNA
    ANN NARDULLI; Fiscal Year: 2010
    ..thioredoxin reductase (TrxR), protein disulfide isomerase (PDI), and apurinic endonuclease 1 (APE1) in the cerebral cortex of C57BL/6 mice, (2) define whether estrogens and/or progestins alter the expression of oxidative stress ..
  5. Molecular Control of Progenitor Cell Polarity and Cortical Neurogenesis
    Song Hai Shi; Fiscal Year: 2010
    Proper formation of the cerebral cortex depends on an orderly production of a large number of neurons during embryonic development...
  6. Basal Ganglia and Higher Cortical Function
    PETER STRICK; Fiscal Year: 2009
    ..We and others have argued that abnormal activity in BG loops with the cerebral cortex could lead not only to motor disorders, but also to the behavioral symptoms associated with neuropsychiatric ..
  7. Structural determinants of DTI observations in developing cortex and white matter
    Christopher D Kroenke; Fiscal Year: 2010
    ..Based on preliminary observations of changes in both WM and cerebral cortex FA in neonatally enucleated ferrets, we hypothesize that changes in WM FA arise from abnormalities of myelin/..
  8. Connexins in Neuronal and Glial Gap Junctions in the Central Nervous System
    John E Rash; Fiscal Year: 2010
    ..throughout the complex circuitry of the mouse brain, to make detailed measurements of "mini" gap junctions in cerebral cortex and hippocampus of both mouse and human brain, and to identify the neuronal subtypes linked by "mini" gap ..
  9. Roles of Gsh1 & 2 genes in telencephalic neurogenesis
    Kenneth Campbell; Fiscal Year: 2006
    ..Two of the major telencephalic regions controlling these processes are the cerebral cortex and the striatum (also known as the caudate-putamen)...
  10. Correlation of Functional and Structural Units in Cerebral Cortex
    Noam Harel; Fiscal Year: 2010
    Correlation of Functional and Structural Units in Cerebral Cortex This proposal is an expansion of our earlier NIH R21 project that explored the spatial relationship between functional magnetic resonance imaging (fMRI) signals and the ..
  11. MECHANISMS OF MOTOR RECOVERY AFTER SUBTOTAL BRAIN INJURY
    Robert J Morecraft; Fiscal Year: 2010
    Stroke and traumatic brain injury often involve the cerebral cortex and are leading causes of functional disability collectively affecting greater than 2 million people per year in the United States...
  12. Correlation of Functional and Structural Units in Cerebral Cortex
    Noam Harel; Fiscal Year: 2009
    Correlation of Functional and Structural Units in Cerebral Cortex This proposal is an expansion of our earlier NIH R21 project that explored the spatial relationship between functional magnetic resonance imaging (fMRI) signals and the ..
  13. Basal Ganglia, Cerebellum, and Higher Cortical Function
    PETER STRICK; Fiscal Year: 2007
    ..In contrast, the basal ganglia and cerebellum receive input from multiple areas of the cerebral cortex located in the frontal, parietal, and temporal lobes...
  14. Basal Ganglia, Cerebellum, and Higher Cortical Function
    PETER STRICK; Fiscal Year: 2003
    ..In contrast, the basal ganglia and cerebellum receive input from multiple areas of the cerebral cortex located in the frontal, parietal, and temporal lobes...
  15. Inhibitory Interneurons in Tourette Syndrome
    Flora Vaccarino; Fiscal Year: 2009
    ..The cerebral cortex-basal ganglia circuitry regulates motor habits and goal-directed behavior...
  16. Inhibitory Interneurons in Tourette Syndrome
    Flora Vaccarino; Fiscal Year: 2007
    ..The cerebral cortex-basal ganglia circuitry regulates motor habits and goal-directed behavior...
  17. FIBROBLAST GROWTH FACTOR CEREBRAL CORTICAL DEVELOPMENT
    Flora Vaccarino; Fiscal Year: 2002
    The size of the cerebral cortex increases during mammalian evolution, underlying an increased complexity of cognitive operations and specialization of functions...
  18. In Vivo Imaging of Neuronal Plasticity in Mouse Visual Cortex
    Elly Nedivi; Fiscal Year: 2011
    ..provide a baseline for future testing of molecules with therapeutic potential for promoting plasticity in the cerebral cortex. Such molecules may be used to compensate for insults or deterioration at multiple levels of the visual ..
  19. In Vivo Imaging of Neuronal Plasticity in Mouse Visual Cortex
    Elly Nedivi; Fiscal Year: 2010
    ..provide a baseline for future testing of molecules with therapeutic potential for promoting plasticity in the cerebral cortex. Such molecules may be used to compensate for insults or deterioration at multiple levels of the visual ..
  20. Morphogenesis and function of the cerebral cortex
    Flora M Vaccarino; Fiscal Year: 2010
    ..This proposal investigates how growth factors of the FGF family establish the primary structure of the cerebral cortex by controlling the genesis of cortical projection neurons from SVZ precursors...
  21. Sentinel cells that report neural and neurovascular signaling
    David Kleinfeld; Fiscal Year: 2007
    ..addiction may be considerably increased if we know how neurotransmitter levels vary in select regions of cerebral cortex. In particular, it is believed that using addictive drug alters attentional processing mediated by ..
  22. Molecular Control of Progenitor Cell Polarity and Cortical Neurogenesis
    Song Hai Shi; Fiscal Year: 2009
    Proper formation of the cerebral cortex depends on an orderly production of a large number of neurons during embryonic development...
  23. Radial Glial Development And Differentiation
    Eva S Anton; Fiscal Year: 2010
    Polarized radial glial cells provide a template for the formation of cerebral cortex. Initially, they function as a source of new neurons and provide a permissive and instructive scaffold for neuronal migration...
  24. NEURAL GENE EXPRESSION IN SLEEP DEPRIVATION AND RECOVERY
    Thomas S Kilduff; Fiscal Year: 2010
    ..During the previous funding period, we identified a population of cells in the cerebral cortex that express the neuronal nitric oxide synthase (nNos) within which the transcription factor Fos is expressed ..
  25. RECONSTRUCTIONS AND REPRESENTATIONS OF CEREBRAL CORTEX
    David C Van Essen; Fiscal Year: 2010
    ..Much of this information pertains to the cerebral cortex and cerebellar cortex, the dominant structures of the human brain...
  26. Molecular Mechanisms of Cerebral Cortical Patterning
    Elizabeth Grove; Fiscal Year: 2005
    The broad goal of this research is to identify the mechanisms that generate the area map of the mammalian cerebral cortex. Using the innovative method of in utero electroporation in living mouse embryos we have found evidence that the ..
  27. REGULATION IN MAMMALIAN NEURAL PROGENITOR CELLS
    Qiang Lu; Fiscal Year: 2009
    ..the growth and maintenance, differentiation, and migration of neural progenitor cells in the mammalian cerebral cortex. During development, neurons of the cerebral cortex arise from neural progenitor cells in the neuroepithelium,..
  28. CELL IDENTITY DETERMINATION IN CEREBRAL CORTEX
    Christopher A Walsh; Fiscal Year: 2010
    ..Proper development of the cerebral cortex is essential for normal cognitive function, and requires the precise completion of a series of developmental ..
  29. Morphogenesis and function of the cerebral cortex
    Flora Vaccarino; Fiscal Year: 2007
    ..focus on the role of Fibroblast Growth Factors (Fgf) receptors on the morphogenesis and function of the cerebral cortex, and particularly frontal regions, whose development is disrupted in schizophrenia...