Genomes and Genes
Summary: Paired anteriolateral evaginations of the prosencephalon plus the lamina terminalis. The cerebral hemispheres are derived from it. Many authors consider cerebrum a synonymous term to telencephalon, though a minority include diencephalon as part of the cerebrum (Anthoney, 1994).
Publications219 found, 100 shown here
- D2-40 antibody immunoreactivity in developing human brain, brain tumors and cultured neural cellsYasuhiro Nakamura
Department of Pathology, St Mary s Hospital, Tsubukuhon Machi, Kurume shi, and Department of Pathology and Biodefense, Saga Medical School, Japan
Mod Pathol 19:974-85. 2006..As D2-40 antibody recognizes cell surface antigen M2A, it might be a candidate cell surface marker for isolation of human neural stem cells/neuronal lineage cells in the fluorescence-activated cell sorting technique...
- Revised nomenclature for avian telencephalon and some related brainstem nucleiAnton Reiner
Department of Anatomy, University of Tennessee Health Science Center, Memphis 38163, USA
J Comp Neurol 473:377-414. 2004..In particular, the outdated terminology implies that most of the avian telencephalon is a hypertrophied basal ganglia, when it is now clear that most of the avian telencephalon is neurochemically,..
- Expression and distribution of JNK/SAPK-associated scaffold protein JSAP1 in developing and adult mouse brainEriko Miura
Department of Anatomy, Hokkaido University School of Medicine, Sapporo, Japan
J Neurochem 97:1431-46. 2006..Therefore, the characteristic cellular expression and subcellular distribution of JSAP1 might be beneficial for cells to efficiently link external stimuli to the JNK MAPK pathway and other intracellular machineries...
- Identification of two novel glial-restricted cell populations in the embryonic telencephalon arising from unique originsFrederick G Strathmann
Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, New York 14642, USA
BMC Dev Biol 7:33. 2007Considerably less attention has been given to understanding the cellular components of gliogenesis in the telencephalon when compared to neuronogenesis, despite the necessity of normal glial cell formation for neurological function...
- Cloning and functional expression of a new epithelial sodium channel delta subunit isoform differentially expressed in neurons of the human and monkey telencephalonTeresa Giraldez
Unidad de Farmacologia, Universidad de La Laguna, La Laguna, Tenerife, Spain
J Neurochem 102:1304-15. 2007..the expression pattern of both the known (delta1) and the new (delta2) isoforms in the human and monkey telencephalon. ENaC delta2 is produced by a combination of alternative transcription start sites, a frame shift in exon 3 ..
- Forebrain gene expression domains and the evolving prosomeric modelLuis Puelles
Department of Human Anatomy and Psychobiology, Faculty of Medicine, University of Murcia, Murcia 30100, Spain
Trends Neurosci 26:469-76. 2003..We sketch a simplified model, in which the secondary prosencephalon (telencephalon plus hypothalamus) is a complex protosegment not subdivided into prosomeres, which exhibits patterning ..
- The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalonW Wisden
Laboratory of Molecular Neuroendocrinology, Zentrum fur Molekulare Biologie, University of Heidelberg, Germany
J Neurosci 12:1040-62. 1992..Based on significant mismatches between alpha 4/delta and gamma mRNAs, we suggest that in vivo, the alpha 4 subunit contributes to GABAA receptors that lack BZ modulation...
- A role for neural determination genes in specifying the dorsoventral identity of telencephalic neuronsC Fode
Institut de G en etique et de Biologie Mol eculaire et Cellulaire, Centre National de la Recherche Scient ifique Institut National de la Sant e et de la Recherche M edicale, Communaut e Urbaine de Strasbourg, France
Genes Dev 14:67-80. 2000..In the telencephalon, the Ngns and Mash1 are expressed at high levels in complementary dorsal and ventral domains, respectively...
- Regulation of mouse embryonic stem cell neural differentiation by retinoic acidMijeong Kim
Department of Cell Biology and Physiology, Washington University Medical School, 660 South Euclid Avenue, St Louis, MO 63110, USA
Dev Biol 328:456-71. 2009..Transcriptional profiling indicates a substantial representation of transit amplifying neuroblasts in SFD cultures not exposed to RA...
- MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factorsMikihito Shibata
Laboratories for Vertebrate Body Plan and Animal Resources and Genetic Engineering, Center for Developmental Biology, RIKEN Kobe, Chuo Ku, Kobe 650 0047, Japan
J Neurosci 31:3407-22. 2011..that microRNA-9 (miR-9) controls neural progenitor proliferation and differentiation in the developing telencephalon by regulating the expression of multiple transcription factors...
- Directed differentiation of telencephalic precursors from embryonic stem cellsKiichi Watanabe
Organogenesis and Neurogenesis Group, Center for Developmental Biology, RIKEN, Kobe 650-0047, Japan
Nat Neurosci 8:288-96. 2005..Thus, in the absence of caudalizing signals, floating aggregates of ES cells generate naive telencephalic precursors that acquire subregional identities by responding to extracellular patterning signals...
- Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fateVishakha S Mangale
Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India
Science 319:304-9. 2008..In addition to providing functional evidence for Lhx2 selector activity, these findings show that the cortical hem is a hippocampal organizer...
- Effects of songs and calls on ZENK expression in the auditory telencephalon of field- and isolate-reared black capped chickadeesLeslie S Phillmore
Department of Psychology, Queen s University, Kingston ON, Canada K7L 3N6
Behav Brain Res 147:125-34. 2003..These findings indicated that the type of conspecific vocalization, as well as the sex of the listener, appear to modulate IEG expression in the songbird ascending auditory pathway...
- Expression of the genes Emx1, Tbr1, and Eomes (Tbr2) in the telencephalon of Xenopus laevis confirms the existence of a ventral pallial division in all tetrapodsAurora Brox
Department of Human Anatomy, Faculty of Medicine, University of Murcia, 30100 Murcia, Spain
J Comp Neurol 474:562-77. 2004..xTbr1) gene and analyzed its expression compared with that of the genes xEomes (Tbr2) and xEmx1 in the telencephalon of the frog Xenopus laevis during embryonic and larval development...
- Transformation of odor representations in target areas of the olfactory bulbEmre Yaksi
Max Planck Institute for Medical Research, Heidelberg, Germany
Nat Neurosci 12:474-82. 2009..This mechanism can extract information about combinations of molecular features from ensembles of active and inactive mitral cells, suggesting that pattern processing in Dp establishes representations of odor objects...
- Slits are chemorepellents endogenous to hypothalamus and steer thalamocortical axons into ventral telencephalonJanet E Braisted
Molecular Neurobiology Laboratory, The Salk Institute, La Jolla, CA 92037, USA
Cereb Cortex 19:i144-51. 2009..along the lateral thalamic surface, and as they approach hypothalamus make a lateral turn into ventral telencephalon. In vitro studies show that hypothalamus releases a chemorepellent for TCAs, and analyses of knockout mice ..
- FoxG1 and TLE2 act cooperatively to regulate ventral telencephalon formationMartin Roth
Faculty of Life Sciences, Michael Smith Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
Development 137:1553-62. 2010..transcriptional repressor that plays a key role in the specification, proliferation and differentiation of the telencephalon, and is expressed from the earliest stages of telencephalic development through to the adult...
- Heterogeneity in progenitor cell subtypes in the ventricular zone of the zebrafish adult telencephalonMartin März
Institute for Toxicology and Genetics, Forschungszentrum Karlsruhe in the Helmholtz Association, Karlsruhe Institute of Technology, Postfach 3640, 76021 Karlsruhe, Germany
Glia 58:870-88. 2010..In the telencephalon, this complexity is enhanced by an organization of the ventricular zone (VZ) in fast and slow-dividing domains,..
- Topography of thalamic projections requires attractive and repulsive functions of Netrin-1 in the ventral telencephalonAshton W Powell
Neuroscience Center, Department of Pharmacology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America
PLoS Biol 6:e116. 2008..topography of thalamocortical (TC) axon projections is initiated before they reach the cortex, in the ventral telencephalon (VTel)...
- Expression of Meis and Pbx genes and their protein products in the developing telencephalon: implications for regional differentiationH Toresson
Wallenberg Neuroscience Center, Division of Neurobiology, Section for Developmental Neurobiology, Lund University, Sweden
Mech Dev 94:183-7. 2000..Curr. Opin. Genet. Dev. 8, 423-429). We have studied the expression of these genes in the mouse telencephalon and found that Meis1 and Meis2 display region-specific patterns of expression from embryonic day (E)10...
- Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferationJoan Seoane
Cancer Biology and Genetics Program and Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, 1300 York Avenue, New York, NY 1002, USA
Cell 117:211-23. 2004..We suggest that the activity of this network confers resistance to TGF-beta-mediated cytostasis during the development of the telencephalic neuroepithelium and in glioblastoma brain tumor cells...
- Emx1 and Emx2 functions in development of dorsal telencephalonM Yoshida
Department of Morphogenesis, Institute of Molecular Embryology and Genetics IMEG, Kumamoto University School of Medicine, Japan
Development 124:101-11. 1997..In the more lateral region of telencephalon, Emx2-deficiency may be compensated for by Emx1 and vice versa...
- A neuronal migratory pathway crossing from diencephalon to telencephalon populates amygdala nucleiFernando García-Moreno
Instituto Cajal Consejo Superior de Investigaciones Cientificas, Laboratory of Telencephalic Development, Molecular, Cellular and Developmental Neurobiology Department, Madrid, Spain
Nat Neurosci 13:680-9. 2010..The diencephalic transcription factor OTP was necessary for this migratory behavior...
- Genetic mapping of Foxb1-cell lineage shows migration from caudal diencephalon to telencephalon and lateral hypothalamusTianyu Zhao
Department of Genes and Behavior, Brain Development Group, Max Planck Institute of Biophysical Chemistry, Gottingen, Germany
Eur J Neurosci 28:1941-55. 2008..The expanded neuroepithelium generates abundant neurons for the medial hypothalamus at the tuberal level. Finally, we have uncovered novel diencephalon-to-telencephalon migrations into septum, piriform cortex and amygdala.
- Zinc-containing neurons are distinct from GABAergic neurons in the telencephalon of the ratL Slomianka
Department of Anatomy and Human Biology, The University of Western Australia, Nedlands
Anat Embryol (Berl) 195:165-74. 1997..Other strongly calbindin-immunoreactive neurons of the telencephalon were never double-labeled...
- Aggression and vasotocin are associated with dominant-subordinate relationships in zebrafishEarl T Larson
Department of Psychology, Northeastern University, Boston, MA 02115, USA
Behav Brain Res 167:94-102. 2006..These results suggest that the vasotocinergic system may play a role in shaping dominant-subordinate relationships and agonistic behavior in this model organism...
- Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalonDaichi Kawaguchi
Institute of Molecular and Cellular Biosciences, University of Tokyo, 1 1 1 Yayoi, Bunkyo ku, Tokyo 113 0032, Japan
Development 135:3849-58. 2008..evidence that the Notch-Delta pathway plays an important role in this selection in the developing mouse telencephalon. We found that the expression patterns of the Notch ligand delta-like 1 (Dll1) and of the active form of ..
- Connections of the lateral and medial divisions of the goldfish telencephalic palliumR Glenn Northcutt
Neurobiology Unit, Scripps Institution of Oceanography, and Department of Neurosciences, School of Medicine, University of California, San Diego, La Jolla, California 92093 0201, USA
J Comp Neurol 494:903-43. 2006..The topography and connections of Dl are remarkably similar to those of the hippocampus of tetrapods, whereas the topography and connections of Dm are similar to those of the amygdala...
- Beta-catenin-mediated Wnt signaling regulates neurogenesis in the ventral telencephalonAlexandra A Gulacsi
Department of Psychiatry, Weill Medical College of Cornell University, 1300 York Avenue, Box 244, New York, New York, 10065, USA
Nat Neurosci 11:1383-91. 2008Development of the telencephalon involves the coordinated growth of diversely patterned brain structures...
- LIM-homeodomain gene Lhx2 regulates the formation of the cortical hemS Bulchand
Department of Biological Sciences, Tata Institute of Fundamental Research, 400005, Mumbai, India
Mech Dev 100:165-75. 2001We are interested in the early mechanisms that initiate regional patterning in the dorsal telencephalon, which gives rise to cerebral cortex...
- Expression of neuron-specific tubulin defines a novel population in the proliferative layers of the developing telencephalonJ R Menezes
Department of Anatomy and Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322
J Neurosci 14:5399-416. 1994..and morphology of immature neurons in the proliferative ventricular and subventricular zones of the developing telencephalon. Mouse brains from embryonic day 12 (E12) to postnatal day 5 (P5) were fixed either with a non-cross-linking ..
- Fibroblast growth factor 8 regulates neocortical guidance of area-specific thalamic innervationTomomi Shimogori
Department of Neurobiology, Pharmacology, and Physiology, University of Chicago, Chicago, Illinois 60637, USA
J Neurosci 25:6550-60. 2005..Our findings demonstrate that thalamocortical axons are directed by sequential, positional cues within the cortex and implicate FGF8 as an indirect regulator of thalamocortical innervation...
- Anatomical distribution and cellular basis for high levels of aromatase activity in the brain of teleost fish: aromatase enzyme and mRNA expression identify glia as sourceP M Forlano
Department of Neurobiology and Behavior, Cornell University, Ithaca, New York 14853, USA
J Neurosci 21:8943-55. 2001..activity in a vocal fish, the plainfin midshipman (Porichthys notatus), and found highest levels in the telencephalon and lower levels in the sonic hindbrain, which was dimorphic between and within (males) sexes...
- The cellular fate of cortical progenitors is not maintained in neurosphere culturesOndrej Machon
Institute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 14220 Prague, Czech Republic
Mol Cell Neurosci 30:388-97. 2005..We isolated neural progenitors from the dorsal telencephalon of D6-GFP mice and cultured them in vitro...
- Chronic antidepressant treatment induces contrasting patterns of synaptophysin and PSA-NCAM expression in different regions of the adult rat telencephalonE Varea
Neurobiology Unit and Program in Basic and Applied Neurosciences, Cell Biology Department, Universitat de Valencia, Spain
Eur Neuropsychopharmacol 17:546-57. 2007..The expression of these molecules is also affected in the entorhinal, the visual and the somatosensory cortices...
- The origin and specification of cortical interneuronsCarl P Wonders
Graduate Program in Neuroscience, Weill Medical College of Cornell University, New York 10021, USA
Nat Rev Neurosci 7:687-96. 2006..Here, we discuss recent data that are beginning to illuminate the origins and specification of distinct subgroups of cortical interneurons...
- Evidences for tangential migrations in Xenopus telencephalon: developmental patterns and cell tracking experimentsNerea Moreno
Department of Cell Biology, Faculty of Biology, University Complutense of Madrid, Spain
Dev Neurobiol 68:504-20. 2008..Our findings strongly suggest that the developing Xenopus telencephalon shares many similarities with amniotes in terms of neuronal specification and migrations...
- Neurons lacking huntingtin differentially colonize brain and survive in chimeric miceA Reiner
Department of Anatomy and Neurobiology, College of Medicine, The University of Tennessee, The Health Science Center, Memphis, Tennessee 38163, USA
J Neurosci 21:7608-19. 2001..The Hdh (-/-) cells were, however, 5-10 times more common in hypothalamus, midbrain, and hindbrain than in telencephalon and thalamus...
- An experimental study of the connections of the telencephalon in the rainbow trout (Oncorhynchus mykiss). I: Olfactory bulb and ventral areaMónica Folgueira
Department of Cell and Molecular Biology, Faculty of Sciences, University of A Coruna, 15071 A Coruna, Spain
J Comp Neurol 480:180-203. 2004..The olfactory bulbs maintain reciprocal connections with several regions of the telencephalon [ventral nucleus of V (Vv), supracommissural nucleus (Vs), posterior zone of D (Dp), preoptic nucleus], and ..
- The teleostean forebrain: a comparative and developmental view based on early proliferation, Pax6 activity and catecholaminergic organizationMario F Wullimann
Brain Research Institute, University of Bremen, Bremen, Germany
Brain Res Bull 57:363-70. 2002..Further, early Pax6 protein distribution in the zebrafish telencephalon corresponds to the migrating stream noted at the pallial-subpallial boundary in amniotes, but a ventricular, ..
- Connections of the pallial telencephalon in the Senegal bichir, PolypterusPreston H Holmes
Neurobiology Unit, Scripps Institution of Oceanography, La Jolla, Calif, USA
Brain Behav Evol 61:113-47. 2003The connections of the dorsal telencephalon (pallium) of the Senegal bichir (Polypterus senegalus) were investigated in order to test the hypothesis that the simple everted pallium of polypterid fishes is directly comparable to the ..
- Role of Emx2 in the development of the reciprocal connectivity between cortex and thalamusGuillermina López-Bendito
Department of Human Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, United Kingdom
J Comp Neurol 451:153-69. 2002..proportion of early thalamocortical projections were misrouted at the border between the diencephalon and telencephalon. This abnormality was associated with displaced connectivity of the internal capsule cells at the diencephalic-..
- Non-oscillatory discharges of an F-prostaglandin responsive neuron population in the olfactory bulb-telencephalon transition area in lake whitefishF Laberge
Department of Zoology, University of Manitoba, Manitoba, Winnipeg, Canada R3T 2N2
Neuroscience 116:1089-95. 2003..responsive to F-prostaglandins in the ventromedial brain tissue strip connecting the olfactory bulb to the telencephalon. Of the 64 neurons examined in this area, 33% showed excitatory and 11% inhibitory responses to F-..
- Telencephalon enlargement by the convergent evolution of expanded subventricular zonesGeorg F Striedter
Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA 92697 4550, USA
Biol Lett 5:134-7. 2009Some mammals and birds independently evolved an enlarged telencephalon. They appear to have done so, at least in part, by developing a thick telencephalic subventricular zone (SVZ)...
- The integration of song environment by catecholaminergic systems innervating the auditory telencephalon of adult female European starlingsKeith W Sockman
Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599 3280, USA
Dev Neurobiol 68:656-68. 2008..that primarily sing long songs over those that primarily sing short songs, and sensitivity of the auditory telencephalon to song length depends on the prevalence of long songs in the environment...
- Neuronal migration and ventral subtype identity in the telencephalon depend on SOX1Antigoni Ekonomou
Mammalian Neurogenesis Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, London, United Kingdom
PLoS Biol 3:e186. 2005..Several transcription factors that are expressed mainly in precursors of the ventral telencephalon have been shown to control neuronal specification, but it has been unclear whether subtype identity is also ..
- Glutamate and regulation of proliferation in the developing mammalian telencephalonKelvin C Luk
Cone Laboratory, Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Canada
Dev Neurosci 26:218-28. 2004..Cells in neither dorsal nor ventral telencephalon-derived neurospheres showed altered proliferation following exposure to either class of ionotropic glutamate ..
- Microglia in the cerebral wall of the human telencephalon at second trimesterPayam Rezaie
Department of Biological Sciences, Faculty of Science, The Open University, Walton Hall, Milton Keynes, MK7 6AA, UK
Cereb Cortex 15:938-49. 2005..investigated the distribution, morphology and phenotype of microglia specifically within the wall of the human telencephalon from 12 to 24 gestational weeks (gw), a period that corresponds to the development of thalamocortical fibres ..
- Spatial learning deficits after the development of dorsomedial telencephalon lesions in goldfishKotaro Saito
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo 108 8345, Japan
Neuroreport 15:2695-9. 2004The effects of lesions in the dorsal area of the caudal telencephalon (Carassius auratus) on the retention of spatial learning in goldfish were examined...
- CB(1) cannabinoid receptor activation dose dependently modulates neuronal activity within caudal but not rostral song control regions of adult zebra finch telencephalonKen Soderstrom
Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
Psychopharmacology (Berl) 199:265-73. 2008CB(1) cannabinoid receptors are distinctly expressed at high density within several regions of zebra finch telencephalon, including those known to be involved in song learning (lMAN and Area X) and production (HVC and RA) because (1) ..
- Gene regulation by song in the auditory telencephalon of songbirdsClaudio V Mello
Neurological Sciences Institute, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA
Front Biosci 9:63-73. 2004..regulator linked to synaptic plasticity, is rapidly and transiently induced in several discrete areas of the telencephalon. This phenomenon is most marked in the caudomedial neostriatum (NCM), a major auditory processing area...
- Acute in utero morphine exposure slows G2/M phase transition in radial glial and basal progenitor cells in the dorsal telencephalon of the E15.5 embryonic mouseTim J Sargeant
School of Biological Sciences, Wellington 6140, New Zealand
Eur J Neurosci 28:1060-7. 2008..5 mouse increases the length of the G(2)/M phase of the radial glial cell cycle in the dorsal telencephalon, as well as slows interkinetic nuclear migration of radial glial nuclei from the basal ventricular zone to the ..
- Developmental origins of species differences in telencephalon and tectum size: morphometric comparisons between a parakeet (Melopsittacus undulatus) and a quail (Colinus virgianus)Georg F Striedter
Department of Neurobiology and Behavior, University of California, Irvine, California 92697, USA
J Comp Neurol 507:1663-75. 2008..larger brains than other birds, relative to their body size, and they possess a proportionately larger telencephalon. For example, the telencephalon occupies approximately 68% of the brain in parakeets but only 52% in bobwhite ..
- Astroglia-microvessel relationship in the developing human telencephalonD Virgintino
Institute of Human Anatomy, Histology and Embryology, University of Bari Medical School, Italy
Int J Dev Biol 42:1165-8. 1998The telencephalon of 12 and 18 week-old human foetuses was examined for evidence of astroglia-microvessel relationship...
- Hepatocyte growth factor/scatter factor is a motogen for interneurons migrating from the ventral to dorsal telencephalonE M Powell
Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
Neuron 30:79-89. 2001Cortical interneurons arise from the proliferative zone of the ventral telencephalon, the ganglionic eminence, and migrate into the developing neocortex...
- AhR-mediated gene expression in the developing mouse telencephalonJulia M Gohlke
Environmental Systems Biology Group, Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, RTP, NC 27709, USA
Reprod Toxicol 28:321-8. 2009..is modulated through an AhR-dependent interaction with key regulatory neuronal differentiation pathways during telencephalon development...
- Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalonEmmanuelle Huillard
INSERM, U873, CEA, iRTSV LTS, 17 Av des Martyrs, F 38054 Grenoble, France
Mol Cell Biol 30:2737-49. 2010..Thus, CK2beta appears to play an essential and uncompensated role in central nervous system development...
- The forebrain of actinopterygians revisitedRudolf Nieuwenhuys
The Netherlands Institute for Neuroscience, Amsterdam, The Netherlands
Brain Behav Evol 73:229-52. 2009..Further, it is proposed that the lateral olfactory tract in teleosts, which supplies most of the olfactory fibers to Dp, is not homologous to the same-named tract in the inverted forebrains of most other vertebrates...
- Clonal analysis by distinct viral vectors identifies bona fide neural stem cells in the adult zebrafish telencephalon and characterizes their division properties and fateIna Rothenaigner
Zebrafish Neurogenetics Group, Laboratory of Neurobiology and Development, Institute of Neurobiology Alfred Fessard, Avenue de la Terrasse, Gif sur Yvette Cedex, France
Development 138:1459-69. 2011..These results characterize fundamental aspects of adult progenitor cells and neurogenesis, and open the way to using virus-based technologies for stable genetic manipulations and clonal analyses in the zebrafish adult brain...
- Cadherin expression by embryonic divisions and derived gray matter structures in the telencephalon of the chickenC Redies
Institute of Anatomy, University of Essen, School of Medicine, D 45122 Essen, Germany
J Comp Neurol 438:253-85. 2001..of three cadherins (cadherin-6B, cadherin-7, and R-cadherin) was studied by immunohistochemistry in the telencephalon of chicken embryos at intermediate stages of development (11 and 15 days of incubation)...
- Stalking the everted telencephalon: comparisons of forebrain organization in basal ray-finned fishes and teleostsMark R Braford
Neuroscience Department, Oberlin College, Oberlin, Ohio 44074, USA
Brain Behav Evol 74:56-76. 2009..These hypotheses are evaluated and some persisting problems are enumerated...
- Integrating microRNA and mRNA expression profiles of neuronal progenitors to identify regulatory networks underlying the onset of cortical neurogenesisJoseph A Nielsen
Section of Developmental Genetics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
BMC Neurosci 10:98. 2009....
- Developmental basis for telencephalon expansion in waterfowl: enlargement prior to neurogenesisChristine J Charvet
Department of Neurobiology, 100 Qureshey Research Laboratory, University of California, Irvine, CA 92697, USA
Proc Biol Sci 276:3421-7. 2009..e. altricial) state, enlarged their telencephalon by delaying telencephalic neurogenesis. To determine whether species that hatch in a relatively mature (i.e...
- Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behaviorGiuliana Caronia
Department of Neurobiology, University of Chicago, Chicago, Illinois 60637, USA
J Neurosci 30:6291-301. 2010..mice that were deficient in Bmpr1b constitutively, and deficient in Bmpr1a conditionally in the dorsal telencephalon. In double mutant male and female mice, the dentate gyrus (DG) was dramatically smaller than in control mice, ..
- Basic helix-loop-helix transcription factors cooperate to specify a cortical projection neuron identityPierre Mattar
Institute of Maternal and Child Health, Hotchkiss Brain Institute, University of Calgary, 2277 HSC, 3330 Hospital Dr NW, Calgary, Alberta, Canada
Mol Cell Biol 28:1456-69. 2008..Strikingly, cortical gene expression was much more rapidly induced by Ngn2 in the dorsal telencephalon (within 12 to 24 h)...
- Asymmetric production of surface-dividing and non-surface-dividing cortical progenitor cellsTakaki Miyata
Laboratory for Cell Culture Development, Brain Science Institute, RIKEN, Saitama 351 0198, Japan
Development 131:3133-45. 2004Mature neocortical layers all derive from the cortical plate (CP), a transient zone in the dorsal telencephalon into which young neurons are continuously delivered...
- Selective expression of presenilin 1 in neural progenitor cells rescues the cerebral hemorrhages and cortical lamination defects in presenilin 1-null mutant micePaul H Wen
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
Development 132:3873-83. 2005..Collectively, these studies demonstrate that Psen1 expression in neural progenitor cells is crucial for cortical development and reveal a novel role for neuroectodermal expression of Psen1 in development of the brain vasculature...
- Selective lengthening of the cell cycle in the neurogenic subpopulation of neural progenitor cells during mouse brain developmentFederico Calegari
Max Planck Institute of Molecular Cell Biology and Genetics, D-01307 Dresden, Germany
J Neurosci 25:6533-8. 2005....
- Neuronal and glial differentiation within expanded glial cultures derived from the lateral and medial ganglionic eminencesCecilia Eriksson
Wallenberg Neuroscience Center, Division of Neurobiology, Lund University, Lund, Sweden
Exp Neurol 184:1058-63. 2003..The present results demonstrate that cells of expanded glial cultures from both the LGE and MGE can give rise to significant and, to a certain extent, region-specific neuronal and glial cell types under differentiating conditions...
- Subventricular zone-derived neuronal progenitors migrate into the subcortical forebrain of postnatal miceSilvia De Marchis
Department of Human and Animal Biology, University of Torino, Torino 10123, Italy
J Comp Neurol 476:290-300. 2004..These data demonstrate that in early postnatal and, to a minor extent in adult mice, SVZ-derived cells contribute new neurons to the subcortical forebrain...
- Members of the NF-kappaB family expressed in zones of active neurogenesis in the postnatal and adult mouse brainSuzanne Denis-Donini
Department of Biology, Section of Zoology and Cytology, University of Milan, Milan, Italy
Brain Res Dev Brain Res 154:81-9. 2005..we examined by immunohistochemistry the expression pattern of various members of this family during postnatal telencephalon development and during adulthood, and we used neuronal and glial markers to identify the cells types where ..
- The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient miceE A Grove
Department of Pharmacological and Physiological Sciences, University of Chicago, Chicago, IL, USA
Development 125:2315-25. 1998..To identify candidate signaling centers in the telencephalon, we isolated Wnt gene fragments from cDNA derived from embryonic mouse telencephalon...
- Engraftment and differentiation of neocortical progenitor cells transplanted to the embryonic brain in uteroBarbara Carletti
Department of Neuroscience and Rita Levi Montalcini Centre for Brain Repai, University of Turin, Italy
J Neurocytol 33:309-19. 2004..to integrate into foreign brain regions, here we examined the fate of precursor cells isolated from the dorsal telencephalon of E12 ss-actin-EGFP transgenic mouse embryos after heterotopic/heterochronic transplantation to the E16 rat ..
- Loss- and gain-of-function analyses reveal targets of Pax6 in the developing mouse telencephalonPontus C Holm
Institute for Stem Cell Research, National Research Center for Environment and Health, Ingolstadter Landstrasse 1, D 85764 Neuherberg Munich, Germany
Mol Cell Neurosci 34:99-119. 2007..murine forebrain neurogenesis, we performed microarray analysis with tissue from the dorsal Pax6-dependent telencephalon and the ventral Pax6-negative telencephalon at the onset of neurogenesis (E12) and at mid-neurogenesis (E15) ..
- Mash1 specifies neurons and oligodendrocytes in the postnatal brainCarlos M Parras
Institut de Génétique et de Biologie Cellulaire et Moléculaire, Illkirch, France
EMBO J 23:4495-505. 2004..Here we show that Mash1, an important proneural gene in the embryonic telencephalon, is broadly expressed in the postnatal SVZ, in progenitors for both neuronal and oligodendrocyte lineages...
- A cell-autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migrationKerry L Ferguson
Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
EMBO J 24:4381-91. 2005..role of the cell cycle regulator, retinoblastoma (Rb) protein, in forebrain development, we studied mice with telencephalon-specific Rb deletions...
- Molecular characterization of adult mouse subventricular zone progenitor cells during the onset of differentiationTimothy P Bonnert
Molecular and Cellular Neuroscience Department, Merck Sharp and Dohme, The Neuroscience Research Centre, Terlings Park, Harlow, Essex CM20 2QR, UK
Eur J Neurosci 24:661-75. 2006..Further characterization of these components could provide greater insight into the mechanisms involved in the regulation of neurogenesis in the adult brain...
- Sexually dimorphic expression of the genes encoding ribosomal proteins L17 and L37 in the song control nuclei of juvenile zebra finchesYu Ping Tang
Michigan State University, Department of Psychology, 108 Giltner Hall, East Lansing, MI 48824-1101, USA
Brain Res 1126:102-8. 2006..Therefore, in a previous study we initiated a screen for differential gene expression in the telencephalon of developing male and female zebra finches...
- Distinct but overlapping functions for the closely related p190 RhoGAPs in neural developmentStephen F Matheson
Department of Biology, Calvin College, Grand Rapids, MI, USA
Dev Neurosci 28:538-50. 2006..We conclude that p190 RhoGAPs control pivotal aspects of neural development, including neuronal differentiation and process outgrowth, and that these effects are mediated by signaling systems that include, but are not limited to, RhoA...
- Origins and migratory routes of murine Cajal-Retzius cellsFernando García Moreno
Instituto Cajal CSIC, Avenida del Doctor Arce 37, 28002 Madrid, Spain
J Comp Neurol 500:419-32. 2007..From their site of origin in the medial wall of the telencephalon, they spread in a caudorostral direction, following an oblique migratory path toward the lateral part of the ..
- Distinct adhesive behaviors of neurons and neural precursor cells during regional differentiation in the mammalian forebrainJ G Whitesides
Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
Dev Biol 169:229-41. 1995..Furthermore, cells from the lateral telencephalon can specifically sort out from medial cells...
- Comparative aspects of p73 and Reelin expression in Cajal-Retzius cells and the cortical hem in lizard, mouse and humanAlfredo Cabrera-Socorro
Departamento de Anatomia, Facultad de Medicina, Universidad de La Laguna, 38071 La Laguna, Tenerife, Spain
Brain Res 1132:59-70. 2007..We analyzed the distribution of Reelin and p73 immunoreactive (ir) neurons in the telencephalon of Lacerta galloti from early embryonic stages to hatching...
- Detection of bone marrow-derived cells expressing a neural phenotype in the human brainPetra Sostak
Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
J Neuropathol Exp Neurol 66:110-6. 2007..Cells with this specific phenotype may contribute to tissue repair in brain regions remote from neurogenic zones...
- Steroidogenic enzymes along the ventricular proliferative zone in the developing songbird brainSarah E London
Interdepartmental Program in Neuroscience, Department of Physiological Science, Laboratory of Neuroendocrinology, University of California, Los Angeles, California 90095 1606, USA
J Comp Neurol 502:507-21. 2007....
- p75 neurotrophin receptor expression defines a population of BDNF-responsive neurogenic precursor cellsKaylene M Young
Queensland Brain Institute, The University of Queensland, Brisbane QLD 4072, Australia
J Neurosci 27:5146-55. 2007....
- Directing neurotransmitter identity of neurones derived from expanded adult neural stem cellsBenedikt Berninger
Department of Physiological Genomics, Institute of Physiology, Ludwig Maximilians University Munich, Munich, Germany
Eur J Neurosci 25:2581-90. 2007..Thus, in-vitro expanded adult NSCs have the competence to become directed towards distinct functional neurotransmitter phenotypes when the appropriate transcriptional cues are provided...
- Cloned multipotential precursors from the mouse cerebrum require FGF-2, whereas glial restricted precursors are stimulated with either FGF-2 or EGFT J Kilpatrick
Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Australia
J Neurosci 15:3653-61. 1995....
- Multiphoton microscope imaging: the behavior of neural progenitor cells in the rostral migratory streamLi Ru Zhao
Department of Neurology, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Chicago, IL 60611, USA
Neurosci Lett 425:83-8. 2007..Cell-cell contacts and microenvironmental changes influence NPC behavior in the RMS. This study may provide insights to help in understanding NPC biology...
- Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrainMagdalena A Petryniak
Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94158 2611, USA
Neuron 55:417-33. 2007Progenitors within the ventral telencephalon can generate GABAergic neurons and oligodendrocytes, but regulation of the neuron-glial switch is poorly understood...
- Basic fibroblast growth factor endows dorsal telencephalic neural progenitors with the ability to differentiate into oligodendrocytes but not gamma-aminobutyric acidergic neuronsMasahiko Abematsu
Department of Cell Fate Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan
J Neurosci Res 83:731-43. 2006....
- Notch3 signaling promotes radial glial/progenitor character in the mammalian telencephalonLouis Dang
Institute for Cell Engineering, Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Dev Neurosci 28:58-69. 2006..Previous work in the mouse telencephalon has shown that activated Notch1 promotes radial glial and astrocytic character in vivo, and fibroblast growth ..
- Neogenin is expressed on neurogenic and gliogenic progenitors in the embryonic and adult central nervous systemDaniel P Fitzgerald
Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia
Gene Expr Patterns 7:784-92. 2007..In summary, this study demonstrates that Neogenin expression is a hallmark of many neural precursor populations (neurogenic and gliogenic) in both the embryonic and adult mammalian central nervous system...
- Alpha 1-adrenoceptor agonists protect against stress-induced death of neural progenitor cellsHiroki Ohashi
Department of Degenerative Neurological Diseases, National Institute of Neuroscience, NCNP, Kodaira, Tokyo 187 8502, Japan
Eur J Pharmacol 573:20-8. 2007....
- Foxg1 suppresses early cortical cell fateCarina Hanashima
Developmental Genetics Program and the Department of Cell Biology, The Skirball Institute of Biomolecular Medicine, New York University Medical Center, 540 First Avenue, New York, NY 10016, USA
Science 303:56-9. 2004..Hence, the competence to generate the earliest born neurons during later cortical development is actively suppressed but not lost...
- The caudal ganglionic eminence is a source of distinct cortical and subcortical cell populationsSusana Nery
Developmental Genetics Program and the Department of Cell Biology, The Skirball Institute of Biomolecular Medicine, New York University Medical Center, 540 First Avenue, New York, New York 10016, USA
Nat Neurosci 5:1279-87. 2002During development, the mammalian ventral telencephalon is comprised of three major proliferative zones: the medial (MGE), lateral (LGE) and caudal (CGE) ganglionic eminences...
- Characterization of CNS precursor subtypes and radial gliaE Hartfuss
Max Planck Institute of Neurobiology, Am Klopferspitz 18a, Martinsried, D 82152, Germany
Dev Biol 229:15-30. 2001..Here we examined the composition of radial glial cells and their proliferation in the mouse telencephalon during development. We found that almost all radial glial cells proliferate throughout neurogenesis...
- Loss of polysialic residues accelerates CNS neural precursor differentiation in pathological conditionsLaurence Decker
INSERM U 546, Laboratoire des Affections la Myéline et des Canaux Ioniques Musculaires, IFRNS, CHU Pitie Salpetriere, Paris, France
Mol Cell Neurosci 19:225-38. 2002....
- The differentiation potential of precursor cells from the mouse lateral ganglionic eminence is restricted by in vitro expansionC Skogh
Wallenberg Neuroscience Center, Division of Neurobiology, Lund University, Solvegatan 17, BMC A11, S-221 84 Lund, Sweden
Neuroscience 120:379-85. 2003..Thus the restriction in differentiation potential of the expanded LGE cultures likely reflects deficiencies in the differentiation conditions used...
- Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalonMalin Parmar
Wallenberg Neuroscience Center, Division of Neurobiology, Lund University, Solvegatan 17, BMC A11, S 221 84 Lund, Sweden
Mol Cell Neurosci 21:645-56. 2002..of precursor cells in expanded neurosphere cultures derived from distinct subregions of the embryonic mouse telencephalon. These regionally derived cultures exhibited differential responses to the mitogens EGF and bFGF, suggesting ..
- Neurotrophins facilitate neuronal differentiation of cultured neural stem cells via induction of mRNA expression of basic helix-loop-helix transcription factors Mash1 and Math1Hisanori Ito
Laboratory of Molecular Biology, Gifu Pharmaceutical University, Gifu, Japan
J Neurosci Res 71:648-58. 2003..Our present results suggest that neurotrophins stimulate neuronal differentiation by altering the balance of expression of various bHLH transcription factors...
- Molecular specification and patterning of progenitor cells in the lateral and medial ganglionic eminencesEric S Tucker
Department of Cell and Molecular Physiology, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, USA
J Neurosci 28:9504-18. 2008..Thus, extrinsic and intrinsic forebrain patterning mechanisms cooperate to establish LGE and MGE progenitor identity, and presumably their capacities to generate distinct classes of neuronal progeny...
- CIRCADIAN SYSTEM AND PRENATAL COCAINE IN ZEBRAFISHIrina Zhdanova; Fiscal Year: 2009..to cocaine during the major periods of cortical (pallium) and limbic system (dorsomedial and dorsolateral telencephalon) development, synchronized with either the nighttime or daytime circadian phase...
- Genetic Control of Basal Telencephalic DevelopmentJohn Rubenstein; Fiscal Year: 2009..The embryonic basal telencephalon generates subcortical nuclei and cortical interneurons that are required for the function of these circuits...
- MYELIN PROTEIN GENE EXPRESSION IN DYSMYELINATING MUTANTSWendy B Macklin; Fiscal Year: 2010..for migration of neurons and oligodendrocyte progenitor cells in cerebellum, optic nerve and embryonic telencephalon, using real time imaging...
- Embryonic regulation of GnRH neuron migration and functionDavid J Kozlowski; Fiscal Year: 2010..These GnRH neurons originate outside the CNS and migrate into the ventral telencephalon and hypothalamus during embryogenesis...
- The Morphogen and Selector Gene Network in the Dorsal Telencephalic MidlineEdwin S Monuki; Fiscal Year: 2010..this project is to better understand the network that governs development of the dorsal midline region in the telencephalon. The proposal is based on a signaling network model we developed that can explain holoprosencephaly, the most ..
- TRANSCRIPTIONAL CONTROL OF MAMMALIAN BRAIN DEVELOPMENTEseng Lai; Fiscal Year: 2001..Results suggested that BF-1 was essential for growth of the telencephalon because at early stages, no significant differences in size of the telencephalic vesicles were apparent...
- Molecular Mechanisms Controlling Formation of Basal Ganglia CircuitryKENNETH J CAMPBELL; Fiscal Year: 2010..PUBLIC HEALTH RELEVANCE: The telencephalon represents the region of the brain most concerned with cognition and voluntary movement...
- Roles of Gsh1 & Gsh2 in Telencephalic NeurogenesisKENNETH J CAMPBELL; Fiscal Year: 2010The mammalian telencephalon represents the region of the brain that displays the most cellular diversity, particularly with respect to neuronal subtypes...
- Roles of Gsh1 & 2 genes in telencephalic neurogenesisKenneth Campbell; Fiscal Year: 2006The telencephalon represents the region of the brain most concerned with cognition and voluntary movement...
- CIRCADIAN SYSTEM AND PRENATAL COCAINE IN ZEBRAFISHIrina V Zhdanova; Fiscal Year: 2010..to cocaine during the major periods of cortical (pallium) and limbic system (dorsomedial and dorsolateral telencephalon) development, synchronized with either the nighttime or daytime circadian phase...
- NEURAL MECHANISMS OF ANOREXIAALAN WATTS; Fiscal Year: 2009..In particular, studies will focus on interactions between the telencephalon, and the hypothalamus and hindbrain, since the telencephalon likely plays a critical role in clinically-..
- NEURAL MECHANISMS OF ANOREXIAAlan G Watts; Fiscal Year: 2010..In particular, studies will focus on interactions between the telencephalon, and the hypothalamus and hindbrain, since the telencephalon likely plays a critical role in clinically-..
- Regulation of GABAergic Neuron DifferentiationBrian Condie; Fiscal Year: 2005..The factors being tested are expressed in the developing mesencephalon, diencephalon and telencephalon and are involved in GABAergic development...
- FIBROBLAST GROWTH FACTOR CEREBRAL CORTICAL DEVELOPMENTFlora Vaccarino; Fiscal Year: 2002..and FGF2 transgenic mice with regard to volume, cell number and apoptosis within histogenic domains of the telencephalon containing neuronal and glial progenitor cells...
- CONNECTIONS OF THE LIMBIC SYSTEM AND HYPOTHALAMUSLARRY SWANSON; Fiscal Year: 2005..each of these broadly defined functions, and has shown that they-along with closely associated limbic telencephalon regions-project topographically to the lateral hypothalamic area (LHA)...
- MYELIN PROTEIN GENE EXPRESSION IN DYSMYELINATING MUTANTSWendy Macklin; Fiscal Year: 2009..for migration of neurons and oligodendrocyte progenitor cells in cerebellum, optic nerve and embryonic telencephalon, using real time imaging...
- TECTOPULVINAR SYSTEM: MOTION DETECTION AND EVOLUTIONHarvey Karten; Fiscal Year: 2004..suggest that the tectopulvinar system is one of the most ancient components of the ascending pathways to the telencephalon and is vital to the process of motion detection...
- Molecular Mechanisms of Cerebral Cortical PatterningElizabeth Grove; Fiscal Year: 2005..that the signaling molecule FGF8 specifies positional identity in the neocortex from a source in the anterior telencephalon. Modifying the endogenous anterior FGF8 signal shifts areas along the anterior/posterior (A/P) axis of the ..
- AUDITORY EXPERIENCE AND ADULT NEURON TURNOVER IN BIRDSJOHN KIRN; Fiscal Year: 2003..In adult warm-blooded vertebrates, the most widespread production of neurons occurs in the avian telencephalon. In songbirds, many new neurons are inserted into the High Vocal Center (HVC), a region necessary for the ..
- Generation of Cortical Motoneurons from Embryonic Stem CellsXue Jun Li; Fiscal Year: 2007..be assessed by their interaction with lower motoneurons in culture and following transplantation to dorsal telencephalon of a chick embryo...
- Morphogenesis and function of the cerebral cortexFlora Vaccarino; Fiscal Year: 2007..test these hypotheses, we will use mice lacking the Fgfr-1 gene product in neuroepithelial cells of the dorsal telencephalon by site-specific recombination (conditional knockout) beginning at either E9.5 or E13.5 stages of development...
- CONVERGENT VS.PARALLEL STRIATAL DOPAMINERGIC AFFERENTSDANIEL ZAHM; Fiscal Year: 2005This project addresses fundamental neuroantomical issues about parts of the telencephalon, diencephalon and brainstem that are strongly influenced by mesotelencephalic dopamine and subserve spontaneous, purposeful behaviors...
- Genetic Control of Basal Telencephalic DevelopmentJohn L R Rubenstein; Fiscal Year: 2010..The embryonic basal telencephalon generates subcortical nuclei and cortical interneurons that are required for the function of these circuits...
- Development of the primary olfactory pathwayHelen Treloar; Fiscal Year: 2009..Axons penetrate the telencephalon, forming a presumptive olfactory nerve layer (pONL)...
- Development of the primary olfactory pathwayHelen Treloar; Fiscal Year: 2007..Axons penetrate the telencephalon, forming a presumptive olfactory nerve layer (pONL)...