Genomes and Genes
Summary: Several groups of nuclei in the thalamus that serve as the major relay centers for sensory impulses in the brain.
Publications203 found, 100 shown here
- Expression of regulatory genes during differentiation of thalamic nuclei in mouse and monkeyEdward G Jones
Center for Neuroscience, University of California, Davis, Davis, California 95616, USA
J Comp Neurol 477:55-80. 2004..in mice at birth (P0) and in adulthood, and in fetal monkeys early and late in the period of gestation when thalamic nuclei are becoming histologically differentiated out of a series of pronuclear masses...
- Diffusion tensor-MRI evidence for extra-axonal neuronal degeneration in caudate and thalamic nuclei of patients with multiple sclerosisS Hannoun
CREATIS, UMR 5220 CNRS and U1044 INSERM, Universite Claude Bernard Lyon1, University of Lyon, France
AJNR Am J Neuroradiol 33:1363-8. 2012..The relationship between diffusivity markers, and atrophy of the caudate and the thalamus, as well as brain lesion load and clinical status of the patients was also explored...
- The effects of selective lesions within the anterior thalamic nuclei on spatial memory in the ratJ P Aggleton
School of Psychology, University of Wales, College of Cardiff, UK
Behav Brain Res 81:189-98. 1996..lesions centred in either the anterior thalamic nucleus (AM), the anterior ventral and anterior dorsal thalamic nuclei (AV/AD), or all three nuclei combined (ANT.T)...
- Contributions of thalamic nuclei to declarative memory functioningYsbrand D Van Der Werf
Dept of Psychology, Cognitive Neuroscience Unit, Montreal Neurological Institute, McGill University, Montreal, Canada
Cortex 39:1047-62. 2003..The two types of function subserved by these groups of thalamic nuclei, focussing on contents vs...
- Automatic segmentation of thalamic nuclei from diffusion tensor magnetic resonance imagingMette R Wiegell
Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13th Street, Room 2301, Charlestown, MA 02129, USA
Neuroimage 19:391-401. 2003..Here, we show that diffusion tensor magnetic resonance imaging (DTI) can noninvasively resolve the major thalamic nuclei based on the characteristic fiber orientation of the corticothalamic/thalamocortical striations within each ..
- Sleep, epilepsy and thalamic reticular inhibitory neuronsMircea Steriade
Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, Canada G1K 7P4
Trends Neurosci 28:317-24. 2005....
- The midline thalamus: alterations and a potential role in limbic epilepsyE H Bertram
Department of Neurology, University of Virginia, Charlottesville, Virginia 22908, USA
Epilepsia 42:967-78. 2001..In this study we examined the midline thalamic regions for involvement in limbic seizures, changes in anatomy and physiology, and the potential role for this region in limbic seizures and epilepsy...
- Intrathalamic sensory connections mediated by the thalamic reticular nucleusJ W Crabtree
Department of Anatomy, School of Medical Sciences, University of Bristol, UK
Cell Mol Life Sci 56:683-700. 1999....
- Segmentation of thalamic nuclei using a modified k-means clustering algorithm and high-resolution quantitative magnetic resonance imaging at 1.5 TSean C L Deoni
Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, PO89, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
Neuroimage 34:117-26. 2007..In this paper we introduce a method for segmenting the individual thalamic nuclei based on high-resolution quantitative magnetic resonance images, providing improved target visualization...
- Thalamic nuclei activity in idiopathic generalized epilepsy: an EEG-fMRI studyL Tyvaert
Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada
Neurology 73:2018-22. 2009..in absence seizures and during spike-and-wave discharges and suggest the involvement of different types of thalamic nuclei. With the development of deep brain stimulation in epilepsy, the role of the thalamic nuclei needs to be ..
- Visualization of thalamic nuclei on high resolution, multi-averaged T1 and T2 maps acquired at 1.5 TSean C L Deoni
Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada
Hum Brain Mapp 25:353-9. 2005..These results confirm our hypothesis and demonstrate the potential high-resolution quantitative imaging for nucleus visualization and surgical planning...
- A morphological analysis of thalamocortical axon fibers of rat posterior thalamic nuclei: a single neuron tracing study with viral vectorsSachi Ohno
Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
Cereb Cortex 22:2840-57. 2012The rostral sector of the posterior thalamic nuclei (POm) is, together with the ventral posterior nuclei (VP), involved in somatosensory information processing in rodents...
- The subcellular organization of neocortical excitatory connectionsLeopoldo Petreanu
Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147, USA
Nature 457:1142-5. 2009..We expressed ChR2 in two thalamic nuclei, the whisker motor cortex and local excitatory neurons and mapped their synapses with pyramidal neurons in ..
- Differential projection of the posterior paralaminar thalamic nuclei to the amygdaloid complex in the ratR Linke
Institut fur Anatomie, Otto von Guericke Universitat, Magdeburg, Germany
Exp Brain Res 134:520-32. 2000..Each of these thalamic nuclei receives a unique pattern of afferent input but an unresolved question is, how each of these thalamic nuclei ..
- Functional organization of the thalamic input to the thalamic reticular nucleusYing Wan Lam
Department of Neurobiology, University of Chicago, Chicago, Illinois 60637, USA
J Neurosci 31:6791-9. 2011....
- Involvement of medial pulvinar thalamic nucleus in human temporal lobe seizuresDominique S Rosenberg
Department of Functional Neurology and Epileptology, Federative Institute of Neurosciences INSERM IFR 19, Bron, France
Epilepsia 47:98-107. 2006..Considering the rich and reciprocal connectivity of the medial pulvinar (PuM) with the temporal lobe, we evaluated a potential participation of this thalamic nucleus in temporal lobe epilepsy (TLE)...
- Laminar and modular organization of prefrontal projections to multiple thalamic nucleiD Xiao
Program in Neuroscience, Boston University, Boston, MA 02215, USA
Neuroscience 161:1067-81. 2009The prefrontal cortex projects to many thalamic nuclei, in pathways associated with cognition, emotion, and action...
- Thalamic nuclei after human blunt head injuryWilliam L Maxwell
Department of Anatomy, Division of Neuroscience and Biomedical Systems, University of Glasgow, UK
J Neuropathol Exp Neurol 65:478-88. 2006..The study provides novel quantitative evidence for differential neuronal loss, with survival after human head injury, from thalamic nuclei associated with different aspects of cortical activation.
- Segmentation of thalamic nuclei from DTI using spectral clusteringUlas Ziyan
MIT Computer Science and Artificial Intelligence Lab, Cambridge MA, USA
Med Image Comput Comput Assist Interv 9:807-14. 2006Recent work shows that diffusion tensor imaging (DTI) can help resolving thalamic nuclei based on the characteristic fiber orientation of the corticothalamic/thalamocortical striations within each nucleus...
- Impairments of thalamic nuclei in idiopathic generalized epilepsy revealed by a study combining morphological and functional connectivity MRIZhengge Wang
Department of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China
PLoS ONE 7:e39701. 2012Neuroimaging evidence suggested that the thalamic nuclei may play different roles in the progress of idiopathic generalized epilepsy (IGE)...
- The effects of lesions to the anterior thalamic nuclei on object-place associations in ratsV Sziklas
Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada
Eur J Neurosci 11:559-66. 1999..A third experiment examined the effects of damage to the anterior thalamic nuclei on the eight-arm radial maze, a spatial working memory task...
- Self-sustained rhythmic activity in the thalamic reticular nucleus mediated by depolarizing GABAA receptor potentialsM Bazhenov
Howard Hughes Medical Institute, Salk Institute, La Jolla, California 92037, USA
Nat Neurosci 2:168-74. 1999..This model predicts that the isolated reticular nucleus could initiate sequences of spindle oscillations in thalamocortical networks in vivo...
- Different mechanisms of secondary neuronal damage in thalamic nuclei after focal cerebral ischemia in ratsMarcel Dihné
Department of Neurology, Rheinisch Westfälische Technische Hochschule Aachen, Aachen, Germany
Stroke 33:3006-11. 2002..In this study differences in secondary damage of the ventroposterior thalamic nucleus (VPN) and the reticular thalamic nucleus (RTN) were investigated with the use of different ischemia models...
- Observation of glucose metabolism in the thalamic nuclei by fusion PET/MRIZang Hee Cho
Neuroscience Research Institute, Gachon University of Medicine and Science, Incheon, South Korea
J Nucl Med 52:401-4. 2011..The anatomy of the thalamus and its connectivity with surrounding areas are known. Localized metabolic activities at the thalamic substructural level have not been measured in vivo in human brains because of limited resolution and contrast...
- Unique combination of anatomy and physiology in cells of the rat paralaminar thalamic nuclei adjacent to the medial geniculate bodyPhilip H Smith
Department of Anatomy, University of Wisconsin, Medical School Madison, 53706, USA
J Comp Neurol 496:314-34. 2006..As with the labeled paralaminar cells, parafascicular cells had physiological features distinguishing them from typical thalamic neurons...
- Complementary distribution of glutamatergic cerebellar and GABAergic basal ganglia afferents to the rat motor thalamic nucleiEriko Kuramoto
Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Eur J Neurosci 33:95-109. 2011Motor thalamic nuclei, ventral anterior (VA), ventral lateral (VL) and ventral medial (VM) nuclei, receive massive glutamatergic and GABAergic afferents from the cerebellum and basal ganglia, respectively...
- Dopaminergic abnormalities in select thalamic nuclei in schizophrenia: involvement of the intracellular signal integrating proteins calcyon and spinophilinSarah M Clinton
Mental Health Research Institute, University of Michigan, 205 Zina Pitcher Place, Ann Arbor, MI 48109 0720, USA
Am J Psychiatry 162:1859-71. 2005..In this study, the authors studied this question by measuring in postmortem brain the expression of molecules associated with dopaminergic neurotransmission...
- Differential activation of anterior and midline thalamic nuclei following retrieval of aversively motivated learning tasksY Yasoshima
Department of Behavioral Physiology, Graduate School of Human Sciences, Osaka University, 1 2 Yamada oka, Suita 565 0871, Japan
Neuroscience 146:922-30. 2007Two thalamic nuclear groups, the anterior thalamic nuclei (ATN) and midline and intralaminar thalamic complex (MITC) have connections to the prefrontal cortex, amygdala, hippocampus and accumbens that are important for learning and ..
- Induction of c-fos in specific thalamic nuclei following stimulation of the pedunculopontine tegmental nucleusJames A Ainge
School of Psychology, University of St Andrews, St Andrews, Fife, KY16 9JU, Scotland
Eur J Neurosci 20:1827-37. 2004..Tracing studies have established that the PPTg has projections to many thalamic nuclei and electrophysiological studies have shown acetylcholine (ACh) to have characteristic effects on thalamic ..
- Cortical and collicular inputs to cells in the rat paralaminar thalamic nuclei adjacent to the medial geniculate bodyPhilip H Smith
Department of Anatomy, University of Wisconsin Medical School Madison, Madison, Wisconsin 53706, USA
J Neurophysiol 98:681-95. 2007..The inhibitory collicular inputs are GABAergic, activate GABA(A) receptors, and terminate on dendrites. Their activation can greatly alter EPSP-generated spike number and timing...
- Mast cells accumulate in the anogenital region of somatosensory thalamic nuclei during estrus in female miceKatalin J Kovács
Department of Veterinary Biomedical Sciences, University of Minnesota, 1988 Fitch Avenue, Rm 295, St Paul, MN 55108, USA
Brain Res 1114:85-97. 2006..During estrus, mast cells were especially concentrated in those regions within the VPL and posterior thalamic nuclei that receive somatosensory information from the anogenital region...
- Feedforward inhibitory control of sensory information in higher-order thalamic nucleiPhilippe Lavallée
Centre de Recherche, Université Laval Robert Giffard, Hôpital Robert Giffard, Quebec, G1J 2G3, Canada
J Neurosci 25:7489-98. 2005..Instead, we propose that this pathway operates through disinhibition, and that the posterior group forwards to the cerebral cortex sensory information that is contingent on motor instructions...
- Organization of projections of rat retrosplenial cortex to the anterior thalamic nucleiH Shibata
Department of Veterinary Anatomy, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Japan
Eur J Neurosci 10:3210-9. 1998The organization of the projections from the retrosplenial cortex (Brodmann's area 29) to the anterior thalamic nuclei was examined in the rat with retrograde transport of the cholera toxin B subunit and anterograde transport of ..
- Lamina-specific deficits in parvalbumin-immunoreactive varicosities in the prefrontal cortex of subjects with schizophrenia: evidence for fewer projections from the thalamusD A Lewis
Department of Psychiatry, University of Pittsburgh, PA 15213, USA
Am J Psychiatry 158:1411-22. 2001..The authors tested the hypothesis that schizophrenia is associated with a selective deficit in a marker of thalamic axon terminals in the middle layers of the prefrontal cortex, the primary zone of termination of thalamic axons...
- Multiarchitectonic and stereotactic atlas of the human thalamusA Morel
Functional Neurosurgery, Neurosurgery Clinic, University Hospital Zurich, Switzerland
J Comp Neurol 387:588-630. 1997..PV), calbindin D-28K (CB), and calretinin (CR) were used as neurochemical markers to further characterize thalamic nuclei and delimit subterritories of functional significance for stereotactic explorations...
- The differential distribution of the growth-associated protein-43 in first and higher order thalamic nuclei of the adult ratS L Feig
Department of Anatomy, University of Wisconsin School of Medicine, 1300 University Avenue, Madison, WI 53706, USA
Neuroscience 136:1147-57. 2005..large terminals that make multiple synaptic contacts on proximal dendrites of relay cells in higher order thalamic nuclei and have been termed "driver" inputs...
- Size gradients of barreloids in the rat thalamusS Haidarliu
Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
J Comp Neurol 429:372-87. 2001..This implies that the extended representation is not merely a reflection of peripheral innervation biases and probably serves an as yet unknown processing function...
- Differential effects mediated by GABAA receptors in thalamic nuclei in lh/lh model of absence seizuresD A Hosford
Department of Medicine Neurology, Duke University Medical Center Durham, NC, USA
Epilepsy Res 27:55-65. 1997..Region-specific GABAA receptor isoforms may underlie the contrasting effects of clonazepam after microinjection into NRT and VLa...
- Expression of excitatory amino acid transporter transcripts in the thalamus of subjects with schizophreniaR E Smith
Department of Psychiatry Mental Health Research Institute, University of Michigan Medical School, Ann Arbor 48109 0720, USA
Am J Psychiatry 158:1393-9. 2001....
- Postmortem assessment of thalamic nuclear volumes in subjects with schizophreniaWilliam Byne
Department of Psychiatry and Pathology, Mount Sinai School of Medicine, New York, USA
Am J Psychiatry 159:59-65. 2002..The authors assessed schizophrenia-associated changes in volume and neuronal number in the mediodorsal nucleus and the pulvinar regions of the thalamus...
- Restricted expression of LGR8 in intralaminar thalamic nuclei of rat brain suggests a role in sensorimotor systemsPei Juan Shen
Howard Florey Institute, The University of Melbourne, Victoria 3010, Australia
Ann N Y Acad Sci 1041:510-5. 2005....
- Synaptic plasticity in thalamic nuclei enhanced by motor skill training in rat with transient middle cerebral artery occlusionYuchuan Ding
Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield, Detroit, MI 48201, USA
Neurol Res 25:189-94. 2003..In treadmill-trained animals, however, similarly intense synaptic plasticity in these two thalamic nuclei was seen only at 28 days...
- Posterior parietal cortex projections to the ventral lateral and some association thalamic nuclei in Macaca mulattaOtar Taktakishvili
Department of Anatomy and Cell Biology, University of Iowa College of Medicine, Iowa City, IA 52242, USA
Brain Res Bull 59:135-50. 2002..The results demonstrate that projections from small loci of the PPC to functionally and connectionally different thalamic nuclei differ anatomically, implying a different functional impact on these diverse targets.
- A possible role of the thalamus in some cases of sudden unexpected death in epilepsyFulvio A Scorza
Epilepsia 48:1036-7. 2007
- Attraction exerted in vivo by grafts of embryonic neocortex on developing thalamic axonsI Frappé
Departement des Neurosciences, CNRS, UMR 6558, Universite de Poitiers, 86022 Poitiers Cedex, France
Exp Neurol 169:264-75. 2001..into the occipital cortex of newborn rats receive inputs from the ventrolateral (VL) and ventromedial (VM) thalamic nuclei which, normally, project to the frontal cortex (25)...
- Cellular dynamics of cholinergically induced alpha (8-13 Hz) rhythms in sensory thalamic nuclei in vitroMagor L Lorincz
School of Biosciences, Cardiff University, Cardiff CF10 3US, United Kingdom
J Neurosci 28:660-71. 2008..of cholinergic activation on the thalamus and, in combination with previous studies, show that sensory thalamic nuclei possess powerful and dynamically reconfigurable mechanisms for generating synchronized alpha activity that ..
- Differences in response to serotonergic activation between first and higher order thalamic nucleiC Varela
Department of Neurobiology, The University of Chicago, 947 E 58th Street, Chicago, IL 60637, USA
Cereb Cortex 19:1776-86. 2009Two types of thalamic nuclei have been recognized: first order, which relay information from subcortical sources, and higher order, which may relay information from one cortical area to another...
- Comparison of oculomotor neuronal activity in paralaminar and mediodorsal thalamus in the rhesus monkeyIkuo Tanibuchi
Department of Physiology, Shiga University of Medical Science, Seta tsukinowa cho, Ohtsu, Shiga 520 2192, Japan
J Neurophysiol 93:614-9. 2005..In the course of mapping the dorsal thalamus, we also studied neurons in a subset of thalamic nuclei (the caudal part of the ventral lateral nucleus (VLc), the oral part of the ventral posterior lateral nucleus ..
- Convergent and complementary projections of the caudal paralaminar thalamic nuclei to rat temporal and insular cortexR Linke
Institut fur Anatomie, Otto von Guericke Universitat Magdeburg, D 39120 Magdeburg, Germany
Cereb Cortex 10:753-71. 2000b>Thalamic nuclei adjacent to the medial geniculate body play a pivotal role in processing of sensory stimuli during emotional situations...
- Differential responses in three thalamic nuclei in moderately disabled, severely disabled and vegetative patients after blunt head injuryWilliam L Maxwell
Laboratory of Human Anatomy, Thomson Building, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
Brain 127:2470-8. 2004..analysis of changes in numbers of neurons within the dorsomedial, ventral posterior and lateral posterior thalamic nuclei in patients assessed by the Glasgow Outcome Scale as moderately disabled (n = 9), severely disabled (n = 12) ..
- Potentiation of local field potentials in the anterior cingulate cortex evoked by the stimulation of the medial thalamic nuclei in ratsJen Chuang Kung
Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan, ROC
Brain Res 953:37-44. 2002..The potentiation of MT-evoked ACC potentials provides a neural basis for synaptic plasticity, which may be essential for the establishment of pain-initiated conditioning behavior and affective responses to noxious stimuli...
- Schizophrenia and sex associated differences in the expression of neuronal and oligodendrocyte-specific genes in individual thalamic nucleiWilliam Byne
Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY, United States
Schizophr Res 98:118-28. 2008..All markers were differentially expressed across nuclei...
- Lesions of specific and nonspecific thalamic nuclei affect prefrontal cortex-dependent aspects of spatial working memoryKathleen R Bailey
Department of Psychology, University of New Hampshire, Durham, NH 03824, USA
Behav Neurosci 119:410-9. 2005..lesions of specific mediodorsal (MD) and nonspecific midline/intralaminar (M/IL) and ventromedial (VM) thalamic nuclei placed to spare the anterior nuclei...
- Rat intralaminar thalamic nuclei projections to the globus pallidus: a biotinylated dextran amine anterograde tracing studyT Yasukawa
Department of Anatomy and Neurobiology, College of Medicine, The University of Tennessee Memphis, Memphis, Tennessee 38163, USA
J Comp Neurol 471:153-67. 2004The topographical organization and ultrastructural features of the intralaminar thalamic nuclei (ITN) projections to the globus pallidus (GP) were studied using the biotinylated dextran amine (BDA) anterograde tracing method in the rat...
- Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirementsR B Lotto
Genes and Development Group, Department of Biomedical Sciences, University Medical School, Edinburgh EH8 9XD, United Kingdom
J Neurosci 21:3904-10. 2001..We suggest that the onset of a requirement for cortex-derived neurotrophic factors initiates a competitive mechanism regulating programmed cell death among dorsal thalamic neurons...
- Rat PPAR delta contains a CGG triplet repeat and is prominently expressed in the thalamic nucleiG Xing
Unit on Gene Mapping and Expression, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA
Biochem Biophys Res Commun 217:1015-25. 1995..These results raise the possibility that PPAR delta might play a role in modulating response to thermal and pain sensations...
- GABA affinity shapes IPSCs in thalamic nucleiClaude M Schofield
Department of Neurology and Neurological Sciences, Stanford University, Stanford, California 94305, USA
J Neurosci 27:7954-62. 2007..These results indicate that within thalamic circuits, a powerful diversity of inhibitory function can result from simple differences in underlying GABA(A) receptor affinity...
- Group II and III metabotropic glutamate receptors and the control of the nucleus reticularis thalami input to rat thalamocortical neurones in vitroJ P Turner
Department of Visual Science, Institute of Ophthalmology, University College London, 11 43 Bath Street, London EC1V 9EL, UK
Neuroscience 122:459-69. 2003..In addition, as NAAG is located in the axons and terminals arising from the TRN, there is the possibility that this dipeptide is also released by these terminals to control the release of GABA during periods of high activity in the TRN...
- Orexin (hypocretin) innervation of the paraventricular nucleus of the thalamusGilbert J Kirouac
Division of Basic Medical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St John s, Newfoundland and Labrador, Canada
Brain Res 1059:179-88. 2005..to describe the extent of orexin fiber innervation of the PVT in comparison to other midline and intralaminar thalamic nuclei and to establish the location and proportion of orexin neurons innervating the PVT...
- Taste pathways that mediate accumbens dopamine release by sapid sucroseAndras Hajnal
Department of Neural and Behavioral Sciences H181, The Pennsylvania State University, College of Medicine, Hershey, PA 17033, USA
Physiol Behav 84:363-9. 2005..168+/-9% for sham operated controls; p<0.02). This represents the first demonstration that the affective character of a sensory stimulus might separate from the thalamocortical system as early as the second central synapse...
- FKBP12 mRNA expression is upregulated by intrinsic CNS neurons regenerating axons into peripheral nerve grafts in the brainM R J Mason
Department of Anatomy and Developmental Biology, University College London, Gower Street, UK
Exp Neurol 181:181-9. 2003..No upregulation was seen in neurons in animals that received freeze-killed grafts, which do not support axonal regeneration. We conclude that FKBP12 is a regeneration-associated gene in intrinsic CNS neurons...
- FMRI of brain activation in a genetic rat model of absence seizuresJeffrey R Tenney
Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Epilepsia 45:576-82. 2004..EEG-triggered functional magnetic resonance imaging (fMRI) was used to identify areas of brain activation during spontaneous spike-and-wave discharges (SWDs) in an epileptic rat strain under awake conditions...
- A maternal blood-borne factor promotes survival of the developing thalamusPeter Landgraf
Institute of Physiology, Otto von Guericke University, Magdeburg, Germany
FASEB J 19:225-7. 2005..e., optic nerve crush), which points to a potential role of the factor not only in neuronal development but also in neuroinflammation after white matter injury...
- Dynamic GABA(A) receptor subtype-specific modulation of the synchrony and duration of thalamic oscillationsVikaas S Sohal
Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford, California 94305 5122, USA
J Neurosci 23:3649-57. 2003..These results not only identify a particular anatomical and molecular target for anti-absence drug design, but also elucidate a specific dynamic mechanism by which inhibitory networks control neural oscillations...
- Non-uniformity of extrinsic connections and columnar organizationKathleen S Rockland
Lab for Cortical Organization and Systematics, RIKEN Brain Science Institute, 2 1, Hirosawa, Wako Shi, Saitama, 351 0198, Japan
J Neurocytol 31:247-53. 2002....
- A comparative reappraisal of projections from the superficial laminae of the dorsal horn in the rat: the forebrainCaroline Gauriau
Institut National de la Sante et de la Recherche Medicale, INSERM U 288, F 75013 Paris, France
J Comp Neurol 468:24-56. 2004..restricted portions of the ventral posterolateral and posteromedial (VPL/VPM), and the posterior group (Po) thalamic nuclei. Lamina I also projects to the triangular posterior (PoT) and the ventral posterior parvicellular (VPPC) ..
- Impaired thalamocortical connectivity in humans during general-anesthetic-induced unconsciousnessNathan S White
Department of Anesthesiology, University of California at Irvine, Irvine, CA 92868, USA
Neuroimage 19:402-11. 2003..These findings support the hypothesis that a mechanistic component underlying general-anesthetic-induced unconsciousness involves disruption of functional interactions within thalamocortical neural networks...
- Thalamocortical connections in the pond turtle Pseudemys scripta elegansDantong Zhu
Neuroscience Group, Division of Basic Biomedical Sciences, University of South Dakota School of Medicine, 414 E Clark St, Vermillion, SD 57069, USA
Brain Behav Evol 65:278-92. 2005..Injections of neurobiotin into these thalamic nuclei confirmed the projections to the cortex...
- Sleep oscillations developing into seizures in corticothalamic systemsM Steriade
Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, Canada G1K 7P4
Epilepsia 44:9-20. 2003..5-2.5 Hz, often associated with fast runs at 10-15 Hz, as in the Lennox-Gastaut syndrome...
- Nociceptive stimulation activates locus coeruleus neurones projecting to the somatosensory thalamus in the ratD L Voisin
Inserm E216 Neurobiologie de la douleur trigéminale, Faculte de Chirurgie Dentaire, 11 Boulevard Charles de Gaulle, 63000 Clermont Ferrand, France
J Physiol 566:929-37. 2005..For the first time, it is shown that nociceptive stimulation activates LC neurones projecting to the somatosensory thalamus. This suggests a new role for LC in modulating nociception within the thalamus...
- Cortical contribution to sensory volleys recorded at thalamic nuclei of lemniscal and paralemniscal pathwaysEwa Kublik
Department of Neurophysiology, Nencki Institute of Experimental Biology, 3 Pasteur St, 02 093 Warsaw, Poland
Acta Neurobiol Exp (Wars) 63:377-82. 2003..The latencies and amplitudes of EPs recorded at both nuclei were not significantly different, which might be attributed to urethane anesthesia...
- Chemical stimulation of the thalamic reticular nucleus inhibits the neuronal activity of the posterior insular cortex in ratsTakamitsu Hanamori
Department of Physiology, Miyazaki Medical College, University of Miyazaki, Kiyotake, Miyazaki 889 1692, Japan
Chem Senses 28:717-28. 2003..The results here indicate that neuronal activity in the posterior insular cortex is controlled by the Rt, which has been reported in other sensory systems...
- Corticothalamic projections from the rat primary somatosensory cortexHerbert P Killackey
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92717, USA
J Neurosci 23:7381-4. 2003..We thus suggest that this cortical zone, which is classically considered part of the primary somatosensory cortex, should be reclassified as higher-order cortex...
- A quantitative map of the circuit of cat primary visual cortexTom Binzegger
Institute of Neuroinformatics, University of Zurich, and Eidgenössische Technische Hochschule Zürich, CH 8057 Zurich, Switzerland
J Neurosci 24:8441-53. 2004..The map of the whole cortical circuit shows that there are very few "strong" but many "weak" excitatory projections, each of which may involve only a few percentage of the total complement of excitatory synapses of a single neuron...
- Higher-order thalamic relays burst more than first-order relaysE J Ramcharan
Center for Complex Systems and Brain Sciences, Florida Atlantic University, 777 Glades Road, Boca Raton, FL 33431, USA
Proc Natl Acad Sci U S A 102:12236-41. 2005..If bursting effectively signals the introduction of new information to a cortical area, as suggested, this increased bursting may be more important in corticocortical transmission than in transmission of primary information to cortex...
- Electrophysiological characterization of synaptic connections between layer VI cortical cells and neurons of the nucleus reticularis thalami in juvenile ratsLuc J Gentet
Institute of Physiology, University of Bern, Buhlplatz 5, 3012 Bern, Switzerland
Eur J Neurosci 19:625-33. 2004..Our results indicate that the corticoreticular pathway fulfills the criteria for 'modulatory' inputs and is temporally restricted. We suggest that it may be involved in coincidence detection of convergent corticoreticular signals...
- Cerebellar thalamic activity in the macaque monkey encodes the duration but not the force or velocity of wrist movementJ J Ivanusic
School of Medical Sciences, The University of New South Wales, Sydney, New South Wales 2052, Australia
Brain Res 1041:181-97. 2005....
- Anterior thalamic mediation of experimental seizures: selective EEG spectral coherenceMarek A Mirski
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA
Epilepsia 44:355-65. 2003..We show that the EEG recorded from AN is highly coherent with surface cortical (CTX) EEG during the immediate preconvulsant period and during the ictal stateough...
- Distinct electrical and chemical connectivity maps in the thalamic reticular nucleus: potential roles in synchronization and sensationCharlotte Deleuze
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
J Neurosci 26:8633-45. 2006....
- Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha(1G) T-type Ca(2+) channelsD Kim
National Creative Research Initiative Center, for Calcium and Learning, Department of Life Science, Pohang University of Science and Technology, 790 784, Pohang, South Korea
Neuron 31:35-45. 2001..Thus, the modulation of the intrinsic firing pattern mediated by alpha(1G) T-type Ca(2+) channels plays a critical role in the genesis of absence seizures in the thalamocortical pathway...
- Zona incerta: Substrate for contralateral interconnectivity in the thalamus of ratsB D Power
Department of Anatomy and Histology, University of Sydney, 2006 Sydney, Australia
J Comp Neurol 436:52-63. 2001..the different ZI sectors (rostral, dorsal, ventral, and caudal) and into intralaminar and higher order dorsal thalamic nuclei of Sprague-Dawley rats by using stereotaxic coordinates...
- Substantia nigra compacta neurons that innervate the reticular thalamic nucleus in the rat also project to striatum or globus pallidus: implications for abnormal motor behaviorV Anaya-Martinez
Departamento de Fisiologia, Biofisica y Neurociencias, CINVESTAV, Apartado Postal 14 740, Mexico D F, 07000 Mexico
Neuroscience 143:477-86. 2006..The fact that lesion of a single dopaminergic neuron can reduce dopamine transmission in more than one structure is probably important in generating the manifestations of Parkinson's disease...
- Successive neuron loss in the thalamus and cortex in a mouse model of infantile neuronal ceroid lipofuscinosisCatherine Kielar
Pediatric Storage Disorders Laboratory, Box P040, MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, King s College London, London, SE5 8AF, UK
Neurobiol Dis 25:150-62. 2007..loss occurred only late in disease progression but were preceded by localized astrocytosis within individual thalamic nuclei and the progressive loss of thalamic neurons that relay different sensory modalities to the cortex...
- Timing of ascending and descending visual signals predicts the response mode of single cells in the thalamic nucleus rotundus of the pigeon (Columba livia)Kristian Folta
Institute for Cognitive Neuroscience, Department of Biopsychology, Faculty of Psychology, Ruhr University Bochum, D 44780 Bochum, Germany
Brain Res 1132:100-9. 2007..These effects might become mediated by intratectal mechanisms, the nucleus ventrolateralis thalami, or the bed nuclei of the tectothalamic tract and might constitute the neural basis of a bihemispheric gating function...
- Visual presentation of phobic stimuli: amygdala activation via an extrageniculostriate pathway?Liesbet Goossens
Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlands
Psychiatry Res 155:113-20. 2007..Moreover, the thalamus findings support the involvement of an extrageniculostriate pathway in the process of phobic fear...
- Different topography of the reticulothalmic inputs to first- and higher-order somatosensory thalamic relays revealed using photostimulationYing Wan Lam
Department of Neurobiology, University of Chicago, IL 60637, USA
J Neurophysiol 98:2903-9. 2007....
- Properties of tactile responses of neurons in rat thalamic ventroposterolateral nucleusJing Bai
Shanghai Institute of Brain Functional Genomics, the Key Laboratories of Ministry of Education of China, East China Normal University, Shanghai 200062, China
Neurosci Bull 23:300-6. 2007..To determine whether the convergences of tactile information also occur at thalamic ventroposterolateral nucleus in rats, we investigated the properties of tactile responses of the thalamic ventroposterolateral nucleus in rats...
- Reciprocal inhibitory connections and network synchrony in the mammalian thalamusM M Huntsman
Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford University, Stanford, CA 94305, USA
Science 283:541-3. 1999..In addition, oscillatory synchrony was dramatically intensified. Thus, recurrent inhibitory connections within reticular nucleus act as "desynchronizers."..
- Heterogeneous output pathways link the anterior pretectal nucleus with the zona incerta and the thalamus in ratKristóf Giber
Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083 Hungary
J Comp Neurol 506:122-40. 2008..parvalbumin-positive, ventral part of the ZI, which contains ZI neurons with axons projecting to higher order thalamic nuclei. The APT-ZI pathway consisted of both gamma-aminobutyric acid (GABA)-negative and GABA-positive components; ..
- Tonotopic control of auditory thalamus frequency tuning by reticular thalamic neuronsNathalie Cotillon-Williams
Laboratoire de Neurobiologie de l Apprentissage, de la Memoire et de la Communication, UMR 8620 CNRS, Universite Paris Sud, Batiment 446, Orsay, France
J Neurophysiol 99:1137-51. 2008..25 octaves; they never occurred for larger distances. This relationship indicates that the functional interactions between TRN cells and ventral MG cells rely on precise topographic connections...
- The trajectory of sensory pathways from the lamina terminalis to the insular and cingulate cortex: a neuroanatomical framework for the generation of thirstJacob H Hollis
Department of Physiology, Monash University, Victoria, Australia
Am J Physiol Regul Integr Comp Physiol 294:R1390-401. 2008..had increased numbers of Fos/CTb double-positive neurons in the paraventricular, rhomboid, and reuniens thalamic nuclei, whereas those rats injected with CTb in the cingulate cortex and challenged with hypertonic saline had ..
- Spikes and bursts in two types of thalamic projection neurons differentially shape sleep patterns and auditory responses in a songbirdRichard H R Hahnloser
Institute of Neuroinformatics, University of Zurich Swiss Federal Institute of Technology Zurich, 8057 Zurich, Switzerland
J Neurosci 28:5040-52. 2008..Our results reveal that cerebral sleep-burst epochs and arousal-related burst suppression are both shaped by sophisticated polysynaptic thalamic mechanisms...
- Mapping of the functional interconnections between thalamic reticular neurons using photostimulationYing Wan Lam
Department of Neurobiology, Pharmacology and Physiology, Univ of Chicago, 947 E 58th St, MC 0926, 316 Abbott, Chicago, IL 60637, USA
J Neurophysiol 96:2593-600. 2006....
- Nucleus- and species-specific properties of the slow (<1 Hz) sleep oscillation in thalamocortical neuronsL Zhu
School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3US, UK
Neuroscience 141:621-36. 2006..properties of this oscillation and compare them with those observed in thalamocortical neurons of three other thalamic nuclei in the cat (ventrobasal complex, medial geniculate body; ventral lateral nucleus) and two thalamic nuclei in ..
- Axonal connections of thalamic posterior paralaminar nuclei with amygdaloid projection neurons to the cholinergic basal forebrain in the ratE Wilhelmi
, , Leipziger Strasse 44, D-39120 Magdeburg, Germany
Neurosci Lett 315:121-4. 2001..These contacts may constitute the morphological substrate for the induction of fast cortical arousal and attention triggered by emotional events...
- Strong, reliable and precise synaptic connections between thalamic relay cells and neurones of the nucleus reticularis in juvenile ratsLuc J Gentet
Institute of Physiology, University of Bern, Buhlplatz 5, 3012 Bern, Switzerland
J Physiol 546:801-11. 2003..8 mV and were completely abolished in the presence of 10 microM bicuculline. Thus, synaptic connections from VB cells to nRT neurones are mainly 'drivers', while a small subset of cells form closed disynaptic loops...
- Organization of reciprocal connections between the perigeniculate nucleus and dorsal lateral geniculate nucleus in the cat: a transneuronal transport studyT Fitzgibbon
Department of Anatomy and Histology, Institute for Biomedical Research and Department of Clinical Ophthalmology, Save Sight Institute, The University of Sydney, NSW 2006, Australia
Vis Neurosci 19:511-20. 2002..However, parts of the PGN immediately adjacent to the LGNd appear devoid of connections with lamina A1 thus creating a thin monocular segment for the contralateral eye...
- Miswiring of limbic thalamocortical projections in the absence of ephrin-A5Daniela Uziel
Universitat Jena, Institut für Allgemeine Zoologie und Tierphysiologie, 07743 Jena, Germany
J Neurosci 22:9352-7. 2002..test whether ephrin-mediated repulsive cues participate in sorting the projections originating from distinct thalamic nuclei, we analyzed the organization of somatosensory and anterior cingulate afferents postnatally in mice lacking ..
- Coding of stimulus frequency by latency in thalamic networks through the interplay of GABAB-mediated feedback and stimulus shapeDavid Golomb
Center for Theoretical Biological Physics, Ben Gurion University of the Negev, PO Box 653, Beer Sheva 84105, Israel
J Neurophysiol 95:1735-50. 2006..We suggest that GABAB-mediated inhibition is a substrate of temporal coding in normal brain function...
- Intrinsic and synaptic properties of neurons in an avian thalamic nucleus during song learningMinmin Luo
Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Neurophysiol 88:1903-14. 2002..Our findings suggest that the signal-processing role of DLM during sensorimotor learning is generally similar to that in adulthood but that quantitative changes in synaptic transmission accompany the development of stereotyped song...
- New intrathalamic pathways allowing modality-related and cross-modality switching in the dorsal thalamusJohn W Crabtree
Medical Research Council Centre for Synaptic Plasticity, Department of Anatomy, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom
J Neurosci 22:8754-61. 2002..Here we show that stimulation of cells in specific dorsal thalamic nuclei evokes robust IPSCs or IPSPs in other specific dorsal thalamic nuclei and vice versa...
- GABA RECEPTORS IN THE THALAMUSYoland Smith; Fiscal Year: 2005..In addition, neurons in CM/Pf, as in most thalamic nuclei, are endowed with intrinsic GABAergic influences from the reticular nucleus and local interneurons...
- CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMAdolf Pfefferbaum; Fiscal Year: 2007..lesion pattern involving the mammillothalamic tract, including the mammillary bodies, fornix, anterior thalamic nuclei, in addition to the superior and inferior colliculi and anterior superior vermis...
- CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMAdolf Pfefferbaum; Fiscal Year: 2009..lesion pattern involving the mammillothalamic tract, including the mammillary bodies, fornix, anterior thalamic nuclei, in addition to the superior and inferior colliculi and anterior superior vermis...
- CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMAdolf Pfefferbaum; Fiscal Year: 2010..lesion pattern involving the mammillothalamic tract, including the mammillary bodies, fornix, anterior thalamic nuclei, in addition to the superior and inferior colliculi and anterior superior vermis...
- CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMAdolf Pfefferbaum; Fiscal Year: 2010
- CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMAdolf Pfefferbaum; Fiscal Year: 2009
- The role of prefrontal cortex and thalamus during trace eyeblink conditioningCraig Weiss; Fiscal Year: 2009..The goal of this proposal is to define the role of interactions between the prefrontal cortex and thalamic nuclei in mediating acquisition and consolidation of the trace eyeblink conditioning task in rabbits...
- The role of prefrontal cortex and thalamus during trace eyeblink conditioningCraig Weiss; Fiscal Year: 2010..The goal of this proposal is to define the role of interactions between the prefrontal cortex and thalamic nuclei in mediating acquisition and consolidation of the trace eyeblink conditioning task in rabbits...
- Modulation of subcortical visual information processingCHARLES LEROY COX; Fiscal Year: 2010..The gating properties of thalamic nuclei, including the dLGN, result from the concerted integration of the intrinsic properties of thalamic neurons, ..
- Medial Pain Inputs to Monkey Anterior Cingulate CortexBrent Vogt; Fiscal Year: 2007..Nociceptive information passes through the midline and intralaminar thalamic nuclei, however, links between the spinothalamic tract and spinoreticulothalamic system to the midline nuclei has ..
- THALAMOSTRIATAL MECHANISMS OF MORPHINE ACTIONRichard Harlan; Fiscal Year: 2003..Rich in mu opiate receptors, the midline-intralaminar thalamic nuclei regulate affective responses to visceral stimuli, relaying this information to specific regions of the ..
- THE CONNECTIONAL ORGANIZATION OF THE THALAMUSJOHN HARTING; Fiscal Year: 2001..Rls in CM-Pf come from the cortex, and share the major synaptic relationships of primary afferents in other thalamic nuclei, we will have a strong argument for changing contemporary views regarding the functions of the CM-Pf (and ..
- NEUROBIOLOGICAL MECHANISMS OF DIENCEPHALIC AMNESIARobert Mair; Fiscal Year: 2002..In contrast Korsakoff's disease and similar amnesia result presumably from damage to thalamic nuclei. The previous 10-years of this project have shown that in a rodent model of thiamine-deficiency amnesia (..
- METHAMPHETAMINE TOXICITY AND CORTICOSTRIATAL GLUTAMATEBryan Yamamoto; Fiscal Year: 1999..second specific aim will be to disrupt corticostriatal glutamatergic transmission by lesioning the ventral thalamic nuclei. The effects of these lesions on METH induced increases in striatal extra cellular glutamate concentrations ..
- Cortico-thalamic Glutamate/GABA mRNA in schizophreniaVahram Haroutunian; Fiscal Year: 2007..cortex (DLPFC) and the mediodorsal nucleus (MDN) of the thalamus; Cingulate cortex and the anterior group of thalamic nuclei; Precentral cortex (Brodmann 4/6) and the ventrolateral nuclear group of the thalamus; Inferior temporal ..
- Functional organization of auditory corticothalamic projection systemsDaniel Llano; Fiscal Year: 2007..with layer 5 auditory corticothalamic projections providing feedforward driving input to the nonlemniscal thalamic nuclei while layer 6 corticothalamic projections provide feedback to all areas of the auditory thalamus...
- Neural Pathways for Conditioned Stimuli in Eyeblink ConditioningJohn Freeman; Fiscal Year: 2007..The PI's laboratory recently discovered that the medial auditory thalamic nuclei (medial division of the medial geniculate, posterior intralaminar nucleus, and suprageniculate nucleus) are ..
- Neural Pathways for Conditioned Stimuli in Eyeblink ConditioningJohn H Freeman; Fiscal Year: 2010..The PI's laboratory recently discovered that the medial auditory thalamic nuclei (medial division of the medial geniculate, posterior intralaminar nucleus, and suprageniculate nucleus) are ..
- VISUAL SYSTEM ORGANIZATION AND DEVELOPMENTVivien Casagrande; Fiscal Year: 2009..Our specific thesis for this proposal is that all thalamic nuclei contain some cell groups that act as drivers and some that act as modulators for multiple cortical areas, ..
- NEURAL CONTROL OF VOLUNTARY MOVEMENTJEFFREY SCHALL; Fiscal Year: 2000..eye field, two cortical areas at the interface of perceptual processing and motor output, and in the thalamic nuclei innervating these areas...
- ANATOMY AND FUNCTION OF THE THALAMUS IN SCHIZOPHRENIAMonte Buchsbaum; Fiscal Year: 2001..relationships between volume loss in specific nuclei of the thalamus and cortical areas associated with these thalamic nuclei. The project brings the resources and the imaging/anatomical researchers of the Mount Sinai Department of ..
- Thalamic Glutamate Dysregulation in SchizophreniaJames Meador Woodruff; Fiscal Year: 2007..postsynaptic receptor complex, by measuring transcript and protein levels expressed in functionally distinct thalamic nuclei. Further, we will perform cell level studies that will permit comparisons of changes in mRNA expression by ..