thalamic nuclei

Summary

Summary: Several groups of nuclei in the thalamus that serve as the major relay centers for sensory impulses in the brain.

Top Publications

  1. ncbi Differential effects mediated by GABAA receptors in thalamic nuclei in lh/lh model of absence seizures
    D A Hosford
    Department of Medicine Neurology, Duke University Medical Center Durham, NC, USA
    Epilepsy Res 27:55-65. 1997
  2. ncbi Dopaminergic abnormalities in select thalamic nuclei in schizophrenia: involvement of the intracellular signal integrating proteins calcyon and spinophilin
    Sarah M Clinton
    Mental Health Research Institute, University of Michigan, 205 Zina Pitcher Place, Ann Arbor, MI 48109 0720, USA
    Am J Psychiatry 162:1859-71. 2005
  3. ncbi Differential activation of anterior and midline thalamic nuclei following retrieval of aversively motivated learning tasks
    Y Yasoshima
    Department of Behavioral Physiology, Graduate School of Human Sciences, Osaka University, 1 2 Yamada oka, Suita 565 0871, Japan
    Neuroscience 146:922-30. 2007
  4. ncbi Unique combination of anatomy and physiology in cells of the rat paralaminar thalamic nuclei adjacent to the medial geniculate body
    Philip H Smith
    Department of Anatomy, University of Wisconsin, Medical School Madison, 53706, USA
    J Comp Neurol 496:314-34. 2006
  5. ncbi The subcellular organization of neocortical excitatory connections
    Leopoldo Petreanu
    Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147, USA
    Nature 457:1142-5. 2009
  6. ncbi Size gradients of barreloids in the rat thalamus
    S Haidarliu
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
    J Comp Neurol 429:372-87. 2001
  7. ncbi Cortical and collicular inputs to cells in the rat paralaminar thalamic nuclei adjacent to the medial geniculate body
    Philip H Smith
    Department of Anatomy, University of Wisconsin Medical School Madison, Madison, Wisconsin 53706, USA
    J Neurophysiol 98:681-95. 2007
  8. ncbi Visualization of thalamic nuclei on high resolution, multi-averaged T1 and T2 maps acquired at 1.5 T
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada
    Hum Brain Mapp 25:353-9. 2005
  9. ncbi Thalamic nuclei activity in idiopathic generalized epilepsy: an EEG-fMRI study
    L Tyvaert
    Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada
    Neurology 73:2018-22. 2009
  10. ncbi Complementary distribution of glutamatergic cerebellar and GABAergic basal ganglia afferents to the rat motor thalamic nuclei
    Eriko Kuramoto
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Eur J Neurosci 33:95-109. 2011

Research Grants

  1. GABA RECEPTORS IN THE THALAMUS
    Yoland Smith; Fiscal Year: 2005
  2. CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISM
    Adolf Pfefferbaum; Fiscal Year: 2010
  3. CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISM
    Adolf Pfefferbaum; Fiscal Year: 2007
  4. CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISM
    Adolf Pfefferbaum; Fiscal Year: 2009
  5. CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISM
    Adolf Pfefferbaum; Fiscal Year: 2009
  6. CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISM
    Adolf Pfefferbaum; Fiscal Year: 2010
  7. The role of prefrontal cortex and thalamus during trace eyeblink conditioning
    Craig Weiss; Fiscal Year: 2009
  8. The role of prefrontal cortex and thalamus during trace eyeblink conditioning
    Craig Weiss; Fiscal Year: 2010
  9. Modulation of subcortical visual information processing
    CHARLES LEROY COX; Fiscal Year: 2010
  10. Medial Pain Inputs to Monkey Anterior Cingulate Cortex
    Brent Vogt; Fiscal Year: 2007

Detail Information

Publications188 found, 100 shown here

  1. ncbi Differential effects mediated by GABAA receptors in thalamic nuclei in lh/lh model of absence seizures
    D A Hosford
    Department of Medicine Neurology, Duke University Medical Center Durham, NC, USA
    Epilepsy Res 27:55-65. 1997
    ..Region-specific GABAA receptor isoforms may underlie the contrasting effects of clonazepam after microinjection into NRT and VLa...
  2. ncbi Dopaminergic abnormalities in select thalamic nuclei in schizophrenia: involvement of the intracellular signal integrating proteins calcyon and spinophilin
    Sarah M Clinton
    Mental Health Research Institute, University of Michigan, 205 Zina Pitcher Place, Ann Arbor, MI 48109 0720, USA
    Am J Psychiatry 162:1859-71. 2005
    ..In this study, the authors studied this question by measuring in postmortem brain the expression of molecules associated with dopaminergic neurotransmission...
  3. ncbi Differential activation of anterior and midline thalamic nuclei following retrieval of aversively motivated learning tasks
    Y Yasoshima
    Department of Behavioral Physiology, Graduate School of Human Sciences, Osaka University, 1 2 Yamada oka, Suita 565 0871, Japan
    Neuroscience 146:922-30. 2007
    Two thalamic nuclear groups, the anterior thalamic nuclei (ATN) and midline and intralaminar thalamic complex (MITC) have connections to the prefrontal cortex, amygdala, hippocampus and accumbens that are important for learning and ..
  4. ncbi Unique combination of anatomy and physiology in cells of the rat paralaminar thalamic nuclei adjacent to the medial geniculate body
    Philip H Smith
    Department of Anatomy, University of Wisconsin, Medical School Madison, 53706, USA
    J Comp Neurol 496:314-34. 2006
    ..As with the labeled paralaminar cells, parafascicular cells had physiological features distinguishing them from typical thalamic neurons...
  5. ncbi The subcellular organization of neocortical excitatory connections
    Leopoldo Petreanu
    Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147, USA
    Nature 457:1142-5. 2009
    ..We expressed ChR2 in two thalamic nuclei, the whisker motor cortex and local excitatory neurons and mapped their synapses with pyramidal neurons in ..
  6. ncbi Size gradients of barreloids in the rat thalamus
    S Haidarliu
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
    J Comp Neurol 429:372-87. 2001
    ..This implies that the extended representation is not merely a reflection of peripheral innervation biases and probably serves an as yet unknown processing function...
  7. ncbi Cortical and collicular inputs to cells in the rat paralaminar thalamic nuclei adjacent to the medial geniculate body
    Philip H Smith
    Department of Anatomy, University of Wisconsin Medical School Madison, Madison, Wisconsin 53706, USA
    J Neurophysiol 98:681-95. 2007
    ..The inhibitory collicular inputs are GABAergic, activate GABA(A) receptors, and terminate on dendrites. Their activation can greatly alter EPSP-generated spike number and timing...
  8. ncbi Visualization of thalamic nuclei on high resolution, multi-averaged T1 and T2 maps acquired at 1.5 T
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada
    Hum Brain Mapp 25:353-9. 2005
    ..These results confirm our hypothesis and demonstrate the potential high-resolution quantitative imaging for nucleus visualization and surgical planning...
  9. ncbi Thalamic nuclei activity in idiopathic generalized epilepsy: an EEG-fMRI study
    L Tyvaert
    Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada
    Neurology 73:2018-22. 2009
    ..in absence seizures and during spike-and-wave discharges and suggest the involvement of different types of thalamic nuclei. With the development of deep brain stimulation in epilepsy, the role of the thalamic nuclei needs to be ..
  10. ncbi Complementary distribution of glutamatergic cerebellar and GABAergic basal ganglia afferents to the rat motor thalamic nuclei
    Eriko Kuramoto
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Eur J Neurosci 33:95-109. 2011
    Motor thalamic nuclei, ventral anterior (VA), ventral lateral (VL) and ventral medial (VM) nuclei, receive massive glutamatergic and GABAergic afferents from the cerebellum and basal ganglia, respectively...
  11. ncbi Segmentation of thalamic nuclei using a modified k-means clustering algorithm and high-resolution quantitative magnetic resonance imaging at 1.5 T
    Sean C L Deoni
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, PO89, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Neuroimage 34:117-26. 2007
    ..In this paper we introduce a method for segmenting the individual thalamic nuclei based on high-resolution quantitative magnetic resonance images, providing improved target visualization...
  12. ncbi Laminar and modular organization of prefrontal projections to multiple thalamic nuclei
    D Xiao
    Program in Neuroscience, Boston University, Boston, MA 02215, USA
    Neuroscience 161:1067-81. 2009
    The prefrontal cortex projects to many thalamic nuclei, in pathways associated with cognition, emotion, and action...
  13. ncbi Differential projection of the posterior paralaminar thalamic nuclei to the amygdaloid complex in the rat
    R Linke
    Institut fur Anatomie, Otto von Guericke Universitat, Magdeburg, Germany
    Exp Brain Res 134:520-32. 2000
    ..Each of these thalamic nuclei receives a unique pattern of afferent input but an unresolved question is, how each of these thalamic nuclei ..
  14. ncbi The differential distribution of the growth-associated protein-43 in first and higher order thalamic nuclei of the adult rat
    S L Feig
    Department of Anatomy, University of Wisconsin School of Medicine, 1300 University Avenue, Madison, WI 53706, USA
    Neuroscience 136:1147-57. 2005
    ..large terminals that make multiple synaptic contacts on proximal dendrites of relay cells in higher order thalamic nuclei and have been termed "driver" inputs...
  15. ncbi Induction of c-fos in specific thalamic nuclei following stimulation of the pedunculopontine tegmental nucleus
    James A Ainge
    School of Psychology, University of St Andrews, St Andrews, Fife, KY16 9JU, Scotland
    Eur J Neurosci 20:1827-37. 2004
    ..Tracing studies have established that the PPTg has projections to many thalamic nuclei and electrophysiological studies have shown acetylcholine (ACh) to have characteristic effects on thalamic ..
  16. ncbi Expression of regulatory genes during differentiation of thalamic nuclei in mouse and monkey
    Edward G Jones
    Center for Neuroscience, University of California, Davis, Davis, California 95616, USA
    J Comp Neurol 477:55-80. 2004
    ..in mice at birth (P0) and in adulthood, and in fetal monkeys early and late in the period of gestation when thalamic nuclei are becoming histologically differentiated out of a series of pronuclear masses...
  17. ncbi Organization of projections of rat retrosplenial cortex to the anterior thalamic nuclei
    H Shibata
    Department of Veterinary Anatomy, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Japan
    Eur J Neurosci 10:3210-9. 1998
    The organization of the projections from the retrosplenial cortex (Brodmann's area 29) to the anterior thalamic nuclei was examined in the rat with retrograde transport of the cholera toxin B subunit and anterograde transport of ..
  18. ncbi Potentiation of local field potentials in the anterior cingulate cortex evoked by the stimulation of the medial thalamic nuclei in rats
    Jen-Chuang Kung
    Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan, ROC
    Brain Res 953:37-44. 2002
    ..The potentiation of MT-evoked ACC potentials provides a neural basis for synaptic plasticity, which may be essential for the establishment of pain-initiated conditioning behavior and affective responses to noxious stimuli...
  19. ncbi Convergent and complementary projections of the caudal paralaminar thalamic nuclei to rat temporal and insular cortex
    R Linke
    Institut fur Anatomie, Otto von Guericke Universitat Magdeburg, D 39120 Magdeburg, Germany
    Cereb Cortex 10:753-71. 2000
    b>Thalamic nuclei adjacent to the medial geniculate body play a pivotal role in processing of sensory stimuli during emotional situations...
  20. ncbi Synaptic plasticity in thalamic nuclei enhanced by motor skill training in rat with transient middle cerebral artery occlusion
    Yuchuan Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield, Detroit, MI 48201, USA
    Neurol Res 25:189-94. 2003
    ..In treadmill-trained animals, however, similarly intense synaptic plasticity in these two thalamic nuclei was seen only at 28 days...
  21. ncbi Attraction exerted in vivo by grafts of embryonic neocortex on developing thalamic axons
    I Frappé
    Departement des Neurosciences, CNRS, UMR 6558, Universite de Poitiers, 86022 Poitiers Cedex, France
    Exp Neurol 169:264-75. 2001
    ..into the occipital cortex of newborn rats receive inputs from the ventrolateral (VL) and ventromedial (VM) thalamic nuclei which, normally, project to the frontal cortex (25)...
  22. ncbi Rat intralaminar thalamic nuclei projections to the globus pallidus: a biotinylated dextran amine anterograde tracing study
    T Yasukawa
    Department of Anatomy and Neurobiology, College of Medicine, The University of Tennessee Memphis, Memphis, Tennessee 38163, USA
    J Comp Neurol 471:153-67. 2004
    The topographical organization and ultrastructural features of the intralaminar thalamic nuclei (ITN) projections to the globus pallidus (GP) were studied using the biotinylated dextran amine (BDA) anterograde tracing method in the rat...
  23. ncbi Comparison of oculomotor neuronal activity in paralaminar and mediodorsal thalamus in the rhesus monkey
    Ikuo Tanibuchi
    Department of Physiology, Shiga University of Medical Science, Seta tsukinowa cho, Ohtsu, Shiga 520 2192, Japan
    J Neurophysiol 93:614-9. 2005
    ..In the course of mapping the dorsal thalamus, we also studied neurons in a subset of thalamic nuclei (the caudal part of the ventral lateral nucleus (VLc), the oral part of the ventral posterior lateral nucleus ..
  24. ncbi Differential responses in three thalamic nuclei in moderately disabled, severely disabled and vegetative patients after blunt head injury
    William L Maxwell
    Laboratory of Human Anatomy, Thomson Building, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
    Brain 127:2470-8. 2004
    ..analysis of changes in numbers of neurons within the dorsomedial, ventral posterior and lateral posterior thalamic nuclei in patients assessed by the Glasgow Outcome Scale as moderately disabled (n = 9), severely disabled (n = 12) ..
  25. ncbi Postmortem assessment of thalamic nuclear volumes in subjects with schizophrenia
    William Byne
    Department of Psychiatry and Pathology, Mount Sinai School of Medicine, New York, USA
    Am J Psychiatry 159:59-65. 2002
    ..The authors assessed schizophrenia-associated changes in volume and neuronal number in the mediodorsal nucleus and the pulvinar regions of the thalamus...
  26. ncbi Lesions of specific and nonspecific thalamic nuclei affect prefrontal cortex-dependent aspects of spatial working memory
    Kathleen R Bailey
    Department of Psychology, University of New Hampshire, Durham, NH 03824, USA
    Behav Neurosci 119:410-9. 2005
    ..lesions of specific mediodorsal (MD) and nonspecific midline/intralaminar (M/IL) and ventromedial (VM) thalamic nuclei placed to spare the anterior nuclei...
  27. ncbi Expression of excitatory amino acid transporter transcripts in the thalamus of subjects with schizophrenia
    R E Smith
    Department of Psychiatry Mental Health Research Institute, University of Michigan Medical School, Ann Arbor 48109 0720, USA
    Am J Psychiatry 158:1393-9. 2001
    ....
  28. ncbi Automatic segmentation of thalamic nuclei from diffusion tensor magnetic resonance imaging
    Mette R Wiegell
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13th Street, Room 2301, Charlestown, MA 02129, USA
    Neuroimage 19:391-401. 2003
    ..Here, we show that diffusion tensor magnetic resonance imaging (DTI) can noninvasively resolve the major thalamic nuclei based on the characteristic fiber orientation of the corticothalamic/thalamocortical striations within each ..
  29. ncbi Restricted expression of LGR8 in intralaminar thalamic nuclei of rat brain suggests a role in sensorimotor systems
    Pei Juan Shen
    Howard Florey Institute, The University of Melbourne, Victoria 3010, Australia
    Ann N Y Acad Sci 1041:510-5. 2005
    ....
  30. ncbi Posterior parietal cortex projections to the ventral lateral and some association thalamic nuclei in Macaca mulatta
    Otar Taktakishvili
    Department of Anatomy and Cell Biology, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Brain Res Bull 59:135-50. 2002
    ..The results demonstrate that projections from small loci of the PPC to functionally and connectionally different thalamic nuclei differ anatomically, implying a different functional impact on these diverse targets.
  31. ncbi A possible role of the thalamus in some cases of sudden unexpected death in epilepsy
    Fulvio A Scorza
    Epilepsia 48:1036-7. 2007
  32. ncbi Cellular dynamics of cholinergically induced alpha (8-13 Hz) rhythms in sensory thalamic nuclei in vitro
    Magor L Lorincz
    School of Biosciences, Cardiff University, Cardiff CF10 3US, United Kingdom
    J Neurosci 28:660-71. 2008
    ..of cholinergic activation on the thalamus and, in combination with previous studies, show that sensory thalamic nuclei possess powerful and dynamically reconfigurable mechanisms for generating synchronized alpha activity that ..
  33. ncbi Differences in response to serotonergic activation between first and higher order thalamic nuclei
    C Varela
    Department of Neurobiology, The University of Chicago, 947 E 58th Street, Chicago, IL 60637, USA
    Cereb Cortex 19:1776-86. 2009
    Two types of thalamic nuclei have been recognized: first order, which relay information from subcortical sources, and higher order, which may relay information from one cortical area to another...
  34. ncbi Schizophrenia and sex associated differences in the expression of neuronal and oligodendrocyte-specific genes in individual thalamic nuclei
    William Byne
    Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY, United States
    Schizophr Res 98:118-28. 2008
    ..All markers were differentially expressed across nuclei...
  35. ncbi GABA affinity shapes IPSCs in thalamic nuclei
    Claude M Schofield
    Department of Neurology and Neurological Sciences, Stanford University, Stanford, California 94305, USA
    J Neurosci 27:7954-62. 2007
    ..These results indicate that within thalamic circuits, a powerful diversity of inhibitory function can result from simple differences in underlying GABA(A) receptor affinity...
  36. ncbi Feedforward inhibitory control of sensory information in higher-order thalamic nuclei
    Philippe Lavallée
    Centre de Recherche, Université Laval Robert Giffard, Hôpital Robert Giffard, Quebec, G1J 2G3, Canada
    J Neurosci 25:7489-98. 2005
    ..Instead, we propose that this pathway operates through disinhibition, and that the posterior group forwards to the cerebral cortex sensory information that is contingent on motor instructions...
  37. ncbi Rat PPAR delta contains a CGG triplet repeat and is prominently expressed in the thalamic nuclei
    G Xing
    Unit on Gene Mapping and Expression, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA
    Biochem Biophys Res Commun 217:1015-25. 1995
    ..These results raise the possibility that PPAR delta might play a role in modulating response to thermal and pain sensations...
  38. ncbi Multiarchitectonic and stereotactic atlas of the human thalamus
    A Morel
    Functional Neurosurgery, Neurosurgery Clinic, University Hospital Zurich, Switzerland
    J Comp Neurol 387:588-630. 1997
    ..PV), calbindin D-28K (CB), and calretinin (CR) were used as neurochemical markers to further characterize thalamic nuclei and delimit subterritories of functional significance for stereotactic explorations...
  39. ncbi Lamina-specific deficits in parvalbumin-immunoreactive varicosities in the prefrontal cortex of subjects with schizophrenia: evidence for fewer projections from the thalamus
    D A Lewis
    Department of Psychiatry, University of Pittsburgh, PA 15213, USA
    Am J Psychiatry 158:1411-22. 2001
    ..The authors tested the hypothesis that schizophrenia is associated with a selective deficit in a marker of thalamic axon terminals in the middle layers of the prefrontal cortex, the primary zone of termination of thalamic axons...
  40. ncbi Tonotopic control of auditory thalamus frequency tuning by reticular thalamic neurons
    Nathalie Cotillon-Williams
    Laboratoire de Neurobiologie de l Apprentissage, de la Memoire et de la Communication, UMR 8620 CNRS, Universite Paris Sud, Batiment 446, Orsay, France
    J Neurophysiol 99:1137-51. 2008
    ..25 octaves; they never occurred for larger distances. This relationship indicates that the functional interactions between TRN cells and ventral MG cells rely on precise topographic connections...
  41. ncbi FMRI of brain activation in a genetic rat model of absence seizures
    Jeffrey R Tenney
    Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Epilepsia 45:576-82. 2004
    ..EEG-triggered functional magnetic resonance imaging (fMRI) was used to identify areas of brain activation during spontaneous spike-and-wave discharges (SWDs) in an epileptic rat strain under awake conditions...
  42. ncbi Cortical contribution to sensory volleys recorded at thalamic nuclei of lemniscal and paralemniscal pathways
    Ewa Kublik
    Department of Neurophysiology, Nencki Institute of Experimental Biology, 3 Pasteur St, 02-093 Warsaw, Poland
    Acta Neurobiol Exp (Wars) 63:377-82. 2003
    ..The latencies and amplitudes of EPs recorded at both nuclei were not significantly different, which might be attributed to urethane anesthesia...
  43. ncbi Electrophysiological characterization of synaptic connections between layer VI cortical cells and neurons of the nucleus reticularis thalami in juvenile rats
    Luc J Gentet
    Institute of Physiology, University of Bern, Buhlplatz 5, 3012 Bern, Switzerland
    Eur J Neurosci 19:625-33. 2004
    ..Our results indicate that the corticoreticular pathway fulfills the criteria for 'modulatory' inputs and is temporally restricted. We suggest that it may be involved in coincidence detection of convergent corticoreticular signals...
  44. ncbi A comparative reappraisal of projections from the superficial laminae of the dorsal horn in the rat: the forebrain
    Caroline Gauriau
    , INSERM U-288, F-75013 Paris, France
    J Comp Neurol 468:24-56. 2004
    ..restricted portions of the ventral posterolateral and posteromedial (VPL/VPM), and the posterior group (Po) thalamic nuclei. Lamina I also projects to the triangular posterior (PoT) and the ventral posterior parvicellular (VPPC) ..
  45. ncbi FKBP12 mRNA expression is upregulated by intrinsic CNS neurons regenerating axons into peripheral nerve grafts in the brain
    M R J Mason
    Department of Anatomy and Developmental Biology, University College London, Gower Street, UK
    Exp Neurol 181:181-9. 2003
    ..No upregulation was seen in neurons in animals that received freeze-killed grafts, which do not support axonal regeneration. We conclude that FKBP12 is a regeneration-associated gene in intrinsic CNS neurons...
  46. ncbi Impaired thalamocortical connectivity in humans during general-anesthetic-induced unconsciousness
    Nathan S White
    Department of Anesthesiology, University of California at Irvine, Irvine, CA 92868, USA
    Neuroimage 19:402-11. 2003
    ..These findings support the hypothesis that a mechanistic component underlying general-anesthetic-induced unconsciousness involves disruption of functional interactions within thalamocortical neural networks...
  47. ncbi Non-uniformity of extrinsic connections and columnar organization
    Kathleen S Rockland
    Lab for Cortical Organization and Systematics, RIKEN Brain Science Institute, 2 1, Hirosawa, Wako Shi, Saitama, 351 0198, Japan
    J Neurocytol 31:247-53. 2002
    ....
  48. ncbi Corticothalamic projections from the rat primary somatosensory cortex
    Herbert P Killackey
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92717, USA
    J Neurosci 23:7381-4. 2003
    ..We thus suggest that this cortical zone, which is classically considered part of the primary somatosensory cortex, should be reclassified as higher-order cortex...
  49. ncbi Group II and III metabotropic glutamate receptors and the control of the nucleus reticularis thalami input to rat thalamocortical neurones in vitro
    J P Turner
    Department of Visual Science, Institute of Ophthalmology, University College London, 11 43 Bath Street, London EC1V 9EL, UK
    Neuroscience 122:459-69. 2003
    ..In addition, as NAAG is located in the axons and terminals arising from the TRN, there is the possibility that this dipeptide is also released by these terminals to control the release of GABA during periods of high activity in the TRN...
  50. ncbi Chemical stimulation of the thalamic reticular nucleus inhibits the neuronal activity of the posterior insular cortex in rats
    Takamitsu Hanamori
    Department of Physiology, Miyazaki Medical College, University of Miyazaki, Kiyotake, Miyazaki 889 1692, Japan
    Chem Senses 28:717-28. 2003
    ..The results here indicate that neuronal activity in the posterior insular cortex is controlled by the Rt, which has been reported in other sensory systems...
  51. ncbi Sleep oscillations developing into seizures in corticothalamic systems
    M Steriade
    Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, Canada G1K 7P4
    Epilepsia 44:9-20. 2003
    ..5-2.5 Hz, often associated with fast runs at 10-15 Hz, as in the Lennox-Gastaut syndrome...
  52. ncbi Nucleus- and species-specific properties of the slow (<1 Hz) sleep oscillation in thalamocortical neurons
    L Zhu
    School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3US, UK
    Neuroscience 141:621-36. 2006
    ..properties of this oscillation and compare them with those observed in thalamocortical neurons of three other thalamic nuclei in the cat (ventrobasal complex, medial geniculate body; ventral lateral nucleus) and two thalamic nuclei in ..
  53. ncbi The trajectory of sensory pathways from the lamina terminalis to the insular and cingulate cortex: a neuroanatomical framework for the generation of thirst
    Jacob H Hollis
    Department of Physiology, Monash University, Victoria, Australia
    Am J Physiol Regul Integr Comp Physiol 294:R1390-401. 2008
    ..had increased numbers of Fos/CTb double-positive neurons in the paraventricular, rhomboid, and reuniens thalamic nuclei, whereas those rats injected with CTb in the cingulate cortex and challenged with hypertonic saline had ..
  54. ncbi A quantitative map of the circuit of cat primary visual cortex
    Tom Binzegger
    Institute of Neuroinformatics, University of Zurich, and Eidgenössische Technische Hochschule Zürich, CH 8057 Zurich, Switzerland
    J Neurosci 24:8441-53. 2004
    ....
  55. ncbi A maternal blood-borne factor promotes survival of the developing thalamus
    Peter Landgraf
    Institute of Physiology, Otto-von-Guericke University, Magdeburg, Germany
    FASEB J 19:225-7. 2005
    ..e., optic nerve crush), which points to a potential role of the factor not only in neuronal development but also in neuroinflammation after white matter injury...
  56. ncbi Orexin (hypocretin) innervation of the paraventricular nucleus of the thalamus
    Gilbert J Kirouac
    Division of Basic Medical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St John s, Newfoundland and Labrador, Canada
    Brain Res 1059:179-88. 2005
    ..to describe the extent of orexin fiber innervation of the PVT in comparison to other midline and intralaminar thalamic nuclei and to establish the location and proportion of orexin neurons innervating the PVT...
  57. ncbi Timing of ascending and descending visual signals predicts the response mode of single cells in the thalamic nucleus rotundus of the pigeon (Columba livia)
    Kristian Folta
    Institute for Cognitive Neuroscience, Department of Biopsychology, Faculty of Psychology, Ruhr University Bochum, D 44780 Bochum, Germany
    Brain Res 1132:100-9. 2007
    ..These effects might become mediated by intratectal mechanisms, the nucleus ventrolateralis thalami, or the bed nuclei of the tectothalamic tract and might constitute the neural basis of a bihemispheric gating function...
  58. ncbi Successive neuron loss in the thalamus and cortex in a mouse model of infantile neuronal ceroid lipofuscinosis
    Catherine Kielar
    Pediatric Storage Disorders Laboratory, Box P040, MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, King s College London, London, SE5 8AF, UK
    Neurobiol Dis 25:150-62. 2007
    ..loss occurred only late in disease progression but were preceded by localized astrocytosis within individual thalamic nuclei and the progressive loss of thalamic neurons that relay different sensory modalities to the cortex...
  59. ncbi Substantia nigra compacta neurons that innervate the reticular thalamic nucleus in the rat also project to striatum or globus pallidus: implications for abnormal motor behavior
    V Anaya-Martinez
    , , CINVESTAV, Apartado Postal 14-740, , 07000 Mexico
    Neuroscience 143:477-86. 2006
    ..The fact that lesion of a single dopaminergic neuron can reduce dopamine transmission in more than one structure is probably important in generating the manifestations of Parkinson's disease...
  60. ncbi Distinct electrical and chemical connectivity maps in the thalamic reticular nucleus: potential roles in synchronization and sensation
    Charlotte Deleuze
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
    J Neurosci 26:8633-45. 2006
    ....
  61. ncbi Mapping of the functional interconnections between thalamic reticular neurons using photostimulation
    Ying-Wan Lam
    Department of Neurobiology, Pharmacology and Physiology, Univ. of Chicago, 947 E. 58th St, MC 0926, 316 Abbott, Chicago, IL 60637, USA
    J Neurophysiol 96:2593-600. 2006
    ....
  62. ncbi Coding of stimulus frequency by latency in thalamic networks through the interplay of GABAB-mediated feedback and stimulus shape
    David Golomb
    Center for Theoretical Biological Physics, Ben Gurion University of the Negev, PO Box 653, Beer Sheva 84105, Israel
    J Neurophysiol 95:1735-50. 2006
    ..We suggest that GABAB-mediated inhibition is a substrate of temporal coding in normal brain function...
  63. ncbi Intracellular activity of cortical and thalamic neurones during high-voltage rhythmic spike discharge in Long-Evans rats in vivo
    Pierre-Olivier Polack
    , , 11 place Marcelin Berthelot, 75231 Paris Cedex 05, France
    J Physiol 571:461-76. 2006
    ..Thus, the present study provides an additional support to the hypothesis that HVRS activity in Long-Evans rats is an absence-like seizure activity...
  64. ncbi Imaging the neural substrates involved in the genesis of pentylenetetrazol-induced seizures
    Mathew E Brevard
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. mathew.brevard.umassmed.edu
    Epilepsia 47:745-54. 2006
    ..in blood oxygen level-dependent (BOLD) signal intensity was noted in the thalamus, especially the anterior thalamic nuclei. Activity in the anterior thalamus peaked approximately 15 s before seizure onset and was more than twofold ..
  65. ncbi Higher-order thalamic relays burst more than first-order relays
    E J Ramcharan
    Center for Complex Systems and Brain Sciences, Florida Atlantic University, 777 Glades Road, Boca Raton, FL 33431, USA
    Proc Natl Acad Sci U S A 102:12236-41. 2005
    ..If bursting effectively signals the introduction of new information to a cortical area, as suggested, this increased bursting may be more important in corticocortical transmission than in transmission of primary information to cortex...
  66. ncbi Visual presentation of phobic stimuli: amygdala activation via an extrageniculostriate pathway?
    Liesbet Goossens
    Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlands
    Psychiatry Res 155:113-20. 2007
    ..Moreover, the thalamus findings support the involvement of an extrageniculostriate pathway in the process of phobic fear...
  67. ncbi Thalamocortical connections in the pond turtle Pseudemys scripta elegans
    Dantong Zhu
    Neuroscience Group, Division of Basic Biomedical Sciences, University of South Dakota School of Medicine, 414 E. Clark St, Vermillion, SD 57069, USA
    Brain Behav Evol 65:278-92. 2005
    ..Injections of neurobiotin into these thalamic nuclei confirmed the projections to the cortex...
  68. ncbi Heterogeneous output pathways link the anterior pretectal nucleus with the zona incerta and the thalamus in rat
    Kristóf Giber
    Department of Cellular and Network Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083 Hungary
    J Comp Neurol 506:122-40. 2008
    ..parvalbumin-positive, ventral part of the ZI, which contains ZI neurons with axons projecting to higher order thalamic nuclei. The APT-ZI pathway consisted of both gamma-aminobutyric acid (GABA)-negative and GABA-positive components; ..
  69. ncbi Taste pathways that mediate accumbens dopamine release by sapid sucrose
    Andras Hajnal
    Department of Neural and Behavioral Sciences H181, The Pennsylvania State University, College of Medicine, Hershey, PA 17033, USA
    Physiol Behav 84:363-9. 2005
    ..168+/-9% for sham operated controls; p<0.02). This represents the first demonstration that the affective character of a sensory stimulus might separate from the thalamocortical system as early as the second central synapse...
  70. ncbi Cerebellar thalamic activity in the macaque monkey encodes the duration but not the force or velocity of wrist movement
    J J Ivanusic
    School of Medical Sciences, The University of New South Wales, Sydney, New South Wales 2052, Australia
    Brain Res 1041:181-97. 2005
    ....
  71. ncbi Properties of tactile responses of neurons in rat thalamic ventroposterolateral nucleus
    Jing Bai
    Shanghai Institute of Brain Functional Genomics, the Key Laboratories of Ministry of Education of China, East China Normal University, Shanghai 200062, China
    Neurosci Bull 23:300-6. 2007
    ..To determine whether the convergences of tactile information also occur at thalamic ventroposterolateral nucleus in rats, we investigated the properties of tactile responses of the thalamic ventroposterolateral nucleus in rats...
  72. ncbi Different topography of the reticulothalmic inputs to first- and higher-order somatosensory thalamic relays revealed using photostimulation
    Ying Wan Lam
    Department of Neurobiology, University of Chicago, IL 60637, USA
    J Neurophysiol 98:2903-9. 2007
    ....
  73. ncbi Nociceptive stimulation activates locus coeruleus neurones projecting to the somatosensory thalamus in the rat
    D L Voisin
    Inserm E216 Neurobiologie de la douleur trigéminale, Faculte de Chirurgie Dentaire, 11 Boulevard Charles de Gaulle, 63000 Clermont Ferrand, France
    J Physiol 566:929-37. 2005
    ..For the first time, it is shown that nociceptive stimulation activates LC neurones projecting to the somatosensory thalamus. This suggests a new role for LC in modulating nociception within the thalamus...
  74. ncbi Sleep, epilepsy and thalamic reticular inhibitory neurons
    Mircea Steriade
    Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, Canada G1K 7P4
    Trends Neurosci 28:317-24. 2005
    ....
  75. ncbi Cortical, callosal, and thalamic connections from primary somatosensory cortex in the naked mole-rat (Heterocephalus glaber), with special emphasis on the connectivity of the incisor representation
    Erin C Henry
    Neuroscience Graduate Program, Vanderbilt University, Nashville, Tennessee 37235, USA
    Anat Rec A Discov Mol Cell Evol Biol 288:626-45. 2006
    ....
  76. ncbi Dynamic GABA(A) receptor subtype-specific modulation of the synchrony and duration of thalamic oscillations
    Vikaas S Sohal
    Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford, California 94305-5122, USA
    J Neurosci 23:3649-57. 2003
    ..These results not only identify a particular anatomical and molecular target for anti-absence drug design, but also elucidate a specific dynamic mechanism by which inhibitory networks control neural oscillations...
  77. ncbi Spikes and bursts in two types of thalamic projection neurons differentially shape sleep patterns and auditory responses in a songbird
    Richard H R Hahnloser
    Institute of Neuroinformatics, University of Zurich Swiss Federal Institute of Technology Zurich, 8057 Zurich, Switzerland
    J Neurosci 28:5040-52. 2008
    ..Our results reveal that cerebral sleep-burst epochs and arousal-related burst suppression are both shaped by sophisticated polysynaptic thalamic mechanisms...
  78. ncbi Electrical synapses in the thalamic reticular nucleus
    Carole E Landisman
    Department of Neuroscience, Division of Biology and Medicine, Brown University, Providence, Rhode Island 02912, USA
    J Neurosci 22:1002-9. 2002
    ..When combined with recent observations from the cerebral cortex, our results imply that electrical synapses are a common mechanism for generating synchrony within networks of inhibitory neurons in the mammalian forebrain...
  79. ncbi Intrinsic and synaptic properties of neurons in an avian thalamic nucleus during song learning
    Minmin Luo
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurophysiol 88:1903-14. 2002
    ..Our findings suggest that the signal-processing role of DLM during sensorimotor learning is generally similar to that in adulthood but that quantitative changes in synaptic transmission accompany the development of stereotyped song...
  80. ncbi New intrathalamic pathways allowing modality-related and cross-modality switching in the dorsal thalamus
    John W Crabtree
    Medical Research Council Centre for Synaptic Plasticity, Department of Anatomy, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom
    J Neurosci 22:8754-61. 2002
    ..Here we show that stimulation of cells in specific dorsal thalamic nuclei evokes robust IPSCs or IPSPs in other specific dorsal thalamic nuclei and vice versa...
  81. ncbi Selective action of orexin (hypocretin) on nonspecific thalamocortical projection neurons
    Laurence Bayer
    , , 1211 Geneva 4, Switzerland
    J Neurosci 22:7835-9. 2002
    ..Among these are the intralaminar and midline thalamic nuclei, which project in turn in a widespread manner to the cerebral cortex within the nonspecific thalamocortical ..
  82. ncbi Do nociceptive signals from the pancreas travel in the dorsal column?
    A K Houghton
    Department of Anatomy and Neurosciences, Marine Biomedical Institute, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 1069, USA
    Pain 89:207-20. 2001
    ..However, the dorsal column pathway may not be the sole route for relaying information about noxious stimulation of the pancreas, particularly that impacting complex behavioral responses...
  83. ncbi Thalamocortical dysrhythmia and the thalamic reticular nucleus in behaving rats
    G Marini
    INB, C N R, 20090 Segrate, Milano, Italy
    Clin Neurophysiol 113:1152-64. 2002
    ....
  84. ncbi Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirements
    R B Lotto
    Genes and Development Group, Department of Biomedical Sciences, University Medical School, Edinburgh EH8 9XD, United Kingdom
    J Neurosci 21:3904-10. 2001
    ..We suggest that the onset of a requirement for cortex-derived neurotrophic factors initiates a competitive mechanism regulating programmed cell death among dorsal thalamic neurons...
  85. ncbi The role of intra-thalamic and thalamocortical circuits in action selection
    M D Humphries
    Department of Psychology, University of Sheffield, UK
    Network 13:131-56. 2002
    ..Thus, we conclude that the results are consistent with these structures having clearly defined functions in action selection...
  86. ncbi Zona incerta: Substrate for contralateral interconnectivity in the thalamus of rats
    B D Power
    Department of Anatomy and Histology, University of Sydney, 2006 Sydney, Australia
    J Comp Neurol 436:52-63. 2001
    ..the different ZI sectors (rostral, dorsal, ventral, and caudal) and into intralaminar and higher order dorsal thalamic nuclei of Sprague-Dawley rats by using stereotaxic coordinates...
  87. ncbi Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha(1G) T-type Ca(2+) channels
    D Kim
    National Creative Research Initiative Center, for Calcium and Learning, Department of Life Science, Pohang University of Science and Technology, 790 784, Pohang, South Korea
    Neuron 31:35-45. 2001
    ..Thus, the modulation of the intrinsic firing pattern mediated by alpha(1G) T-type Ca(2+) channels plays a critical role in the genesis of absence seizures in the thalamocortical pathway...
  88. ncbi Axonal connections of thalamic posterior paralaminar nuclei with amygdaloid projection neurons to the cholinergic basal forebrain in the rat
    E Wilhelmi
    , , Leipziger Strasse 44, D-39120 Magdeburg, Germany
    Neurosci Lett 315:121-4. 2001
    ..These contacts may constitute the morphological substrate for the induction of fast cortical arousal and attention triggered by emotional events...
  89. ncbi Miswiring of limbic thalamocortical projections in the absence of ephrin-A5
    Daniela Uziel
    Universitat Jena, Institut für Allgemeine Zoologie und Tierphysiologie, 07743 Jena, Germany
    J Neurosci 22:9352-7. 2002
    ..test whether ephrin-mediated repulsive cues participate in sorting the projections originating from distinct thalamic nuclei, we analyzed the organization of somatosensory and anterior cingulate afferents postnatally in mice lacking ..
  90. ncbi Reciprocal inhibitory connections and network synchrony in the mammalian thalamus
    M M Huntsman
    Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford University, Stanford, CA 94305, USA
    Science 283:541-3. 1999
    ..In addition, oscillatory synchrony was dramatically intensified. Thus, recurrent inhibitory connections within reticular nucleus act as "desynchronizers."..
  91. ncbi Degeneration of thalamic neurons in "Purkinje cell degeneration" mutant mice. I. Distribution of neuron loss
    R L Sidman
    J Comp Neurol 234:277-97. 1985
    ..The pcd allele affects a diverse assortment of specific relay nuclei; degeneration has not been recognized in thalamic nuclei characterized primarily or exclusively by subcortical projections or by cortical projections directed ..
  92. ncbi Anterior thalamic mediation of experimental seizures: selective EEG spectral coherence
    Marek A Mirski
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Epilepsia 44:355-65. 2003
    ..We show that the EEG recorded from AN is highly coherent with surface cortical (CTX) EEG during the immediate preconvulsant period and during the ictal stateough...
  93. ncbi Strong, reliable and precise synaptic connections between thalamic relay cells and neurones of the nucleus reticularis in juvenile rats
    Luc J Gentet
    Institute of Physiology, University of Bern, , 3012 Bern, Switzerland
    J Physiol 546:801-11. 2003
    ..8 mV and were completely abolished in the presence of 10 microM bicuculline. Thus, synaptic connections from VB cells to nRT neurones are mainly 'drivers', while a small subset of cells form closed disynaptic loops...
  94. ncbi Organization of reciprocal connections between the perigeniculate nucleus and dorsal lateral geniculate nucleus in the cat: a transneuronal transport study
    T Fitzgibbon
    Department of Anatomy and Histology, Institute for Biomedical Research and Department of Clinical Ophthalmology, Save Sight Institute, The University of Sydney, NSW 2006, Australia
    Vis Neurosci 19:511-20. 2002
    ..However, parts of the PGN immediately adjacent to the LGNd appear devoid of connections with lamina A1 thus creating a thin monocular segment for the contralateral eye...
  95. ncbi Different mechanisms of secondary neuronal damage in thalamic nuclei after focal cerebral ischemia in rats
    Marcel Dihné
    Department of Neurology, Rheinisch Westfälische Technische Hochschule Aachen, Aachen, Germany
    Stroke 33:3006-11. 2002
    ..In this study differences in secondary damage of the ventroposterior thalamic nucleus (VPN) and the reticular thalamic nucleus (RTN) were investigated with the use of different ischemia models...
  96. ncbi Efferent projections of infralimbic and prelimbic areas of the medial prefrontal cortex in the Japanese monkey, Macaca fuscata
    T Chiba
    Department of Anatomy and Neurobiology, Chiba University School of Medicine, Inohana 1 8 1, Chuo Ku, 260 8670, Chiba, Japan
    Brain Res 888:83-101. 2001
    ..nucleus (TM), medial part of the magnocellular and dorsal part of the parvicellular (MDpc) dorsomedial thalamic nuclei, reunience and medial part of the medial pulvinar nucleus, and dorso-lateral part of the periaqueductal gray (..
  97. ncbi Brain and sense organ anatomy and histology of two species of phyletically basal non-Antarctic thornfishes of the Antarctic suborder Notothenioidei (Perciformes: Bovichtidae)
    Joseph T Eastman
    Department of Biomedical Sciences, College of Osteopathic Medicine, Ohio University, Athens, Ohio 45701 2979, USA
    J Morphol 268:485-503. 2007
    ..Typical of perciforms, the brains of both species have a well-developed tectum and telencephalon and robust thalamic nuclei. The telencephalon of C...
  98. ncbi Awakenings and awareness recovery in disorders of consciousness: is there a role for drugs?
    Francesca Pistoia
    Hospital San Raffaele, Cassino, Italy
    CNS Drugs 24:625-38. 2010
    ..to the ascending reticular system (which is functionally connected to the cerebral cortex by intralaminar thalamic nuclei)...
  99. ncbi Regional (14C) 2-deoxyglucose uptake during forelimb movements evoked by rat motor cortex stimulation: cortex, diencephalon, midbrain
    F R Sharp
    Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla, California 92093, USA
    J Comp Neurol 224:259-85. 1984
    ..b>Thalamic nuclei that increased (14C) 2DG uptake included anterior dorsolateral reticular (R), ventral and central ..
  100. ncbi Experimental localization of muscarinic receptor subtypes to cingulate cortical afferents and neurons
    B A Vogt
    Department of Anatomy, Boston University School of Medicine, Massachusetts 02118
    J Neurosci 8:643-52. 1988
    ..2. Terminal axons of neurons in the anterior thalamic nuclei (ATN) have M2 receptors based on the following observations...
  101. ncbi Sexual dimorphism in the response to N-methyl-D-aspartate receptor antagonists and morphine on behavior and c-Fos induction in the rat brain
    D N D'Souza
    Department of Anatomy, Tulane University School of Medicine, New Orleans, LA 70112, USA
    Neuroscience 93:1539-47. 1999
    ..In the midline intralaminar thalamic nuclei, female rats showed less induction than males...

Research Grants72

  1. GABA RECEPTORS IN THE THALAMUS
    Yoland Smith; Fiscal Year: 2005
    ..In addition, neurons in CM/Pf, as in most thalamic nuclei, are endowed with intrinsic GABAergic influences from the reticular nucleus and local interneurons...
  2. CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISM
    Adolf Pfefferbaum; Fiscal Year: 2010
    ..lesion pattern involving the mammillothalamic tract, including the mammillary bodies, fornix, anterior thalamic nuclei, in addition to the superior and inferior colliculi and anterior superior vermis...
  3. CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISM
    Adolf Pfefferbaum; Fiscal Year: 2007
    ..lesion pattern involving the mammillothalamic tract, including the mammillary bodies, fornix, anterior thalamic nuclei, in addition to the superior and inferior colliculi and anterior superior vermis...
  4. CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISM
    Adolf Pfefferbaum; Fiscal Year: 2009
    ..lesion pattern involving the mammillothalamic tract, including the mammillary bodies, fornix, anterior thalamic nuclei, in addition to the superior and inferior colliculi and anterior superior vermis...
  5. CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISM
    Adolf Pfefferbaum; Fiscal Year: 2009
    ..lesion pattern involving the mammillothalamic tract, including the mammillary bodies, fornix, anterior thalamic nuclei, in addition to the superior and inferior colliculi and anterior superior vermis...
  6. CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISM
    Adolf Pfefferbaum; Fiscal Year: 2010
    ..lesion pattern involving the mammillothalamic tract, including the mammillary bodies, fornix, anterior thalamic nuclei, in addition to the superior and inferior colliculi and anterior superior vermis...
  7. The role of prefrontal cortex and thalamus during trace eyeblink conditioning
    Craig Weiss; Fiscal Year: 2009
    ..The goal of this proposal is to define the role of interactions between the prefrontal cortex and thalamic nuclei in mediating acquisition and consolidation of the trace eyeblink conditioning task in rabbits...
  8. The role of prefrontal cortex and thalamus during trace eyeblink conditioning
    Craig Weiss; Fiscal Year: 2010
    ..The goal of this proposal is to define the role of interactions between the prefrontal cortex and thalamic nuclei in mediating acquisition and consolidation of the trace eyeblink conditioning task in rabbits...
  9. Modulation of subcortical visual information processing
    CHARLES LEROY COX; Fiscal Year: 2010
    ..The gating properties of thalamic nuclei, including the dLGN, result from the concerted integration of the intrinsic properties of thalamic neurons, ..
  10. Medial Pain Inputs to Monkey Anterior Cingulate Cortex
    Brent Vogt; Fiscal Year: 2007
    ..Nociceptive information passes through the midline and intralaminar thalamic nuclei, however, links between the spinothalamic tract and spinoreticulothalamic system to the midline nuclei has ..
  11. THALAMOSTRIATAL MECHANISMS OF MORPHINE ACTION
    Richard Harlan; Fiscal Year: 2003
    ..Rich in mu opiate receptors, the midline-intralaminar thalamic nuclei regulate affective responses to visceral stimuli, relaying this information to specific regions of the ..
  12. THE CONNECTIONAL ORGANIZATION OF THE THALAMUS
    JOHN HARTING; Fiscal Year: 2001
    ..Rls in CM-Pf come from the cortex, and share the major synaptic relationships of primary afferents in other thalamic nuclei, we will have a strong argument for changing contemporary views regarding the functions of the CM-Pf (and ..
  13. NEUROBIOLOGICAL MECHANISMS OF DIENCEPHALIC AMNESIA
    Robert Mair; Fiscal Year: 2002
    ..In contrast Korsakoff's disease and similar amnesia result presumably from damage to thalamic nuclei. The previous 10-years of this project have shown that in a rodent model of thiamine-deficiency amnesia (..
  14. METHAMPHETAMINE TOXICITY AND CORTICOSTRIATAL GLUTAMATE
    Bryan Yamamoto; Fiscal Year: 1999
    ..second specific aim will be to disrupt corticostriatal glutamatergic transmission by lesioning the ventral thalamic nuclei. The effects of these lesions on METH induced increases in striatal extra cellular glutamate concentrations ..
  15. Cortico-thalamic Glutamate/GABA mRNA in schizophrenia
    Vahram Haroutunian; Fiscal Year: 2007
    ..cortex (DLPFC) and the mediodorsal nucleus (MDN) of the thalamus; Cingulate cortex and the anterior group of thalamic nuclei; Precentral cortex (Brodmann 4/6) and the ventrolateral nuclear group of the thalamus; Inferior temporal ..
  16. Functional organization of auditory corticothalamic projection systems
    Daniel Llano; Fiscal Year: 2007
    ..with layer 5 auditory corticothalamic projections providing feedforward driving input to the nonlemniscal thalamic nuclei while layer 6 corticothalamic projections provide feedback to all areas of the auditory thalamus...
  17. Neural Pathways for Conditioned Stimuli in Eyeblink Conditioning
    John H Freeman; Fiscal Year: 2010
    ..The PI's laboratory recently discovered that the medial auditory thalamic nuclei (medial division of the medial geniculate, posterior intralaminar nucleus, and suprageniculate nucleus) are ..
  18. Neural Pathways for Conditioned Stimuli in Eyeblink Conditioning
    John Freeman; Fiscal Year: 2007
    ..The PI's laboratory recently discovered that the medial auditory thalamic nuclei (medial division of the medial geniculate, posterior intralaminar nucleus, and suprageniculate nucleus) are ..
  19. VISUAL SYSTEM ORGANIZATION AND DEVELOPMENT
    Vivien Casagrande; Fiscal Year: 2009
    ..Our specific thesis for this proposal is that all thalamic nuclei contain some cell groups that act as drivers and some that act as modulators for multiple cortical areas, ..
  20. NEURAL CONTROL OF VOLUNTARY MOVEMENT
    JEFFREY SCHALL; Fiscal Year: 2000
    ..eye field, two cortical areas at the interface of perceptual processing and motor output, and in the thalamic nuclei innervating these areas...
  21. ANATOMY AND FUNCTION OF THE THALAMUS IN SCHIZOPHRENIA
    Monte Buchsbaum; Fiscal Year: 2001
    ..relationships between volume loss in specific nuclei of the thalamus and cortical areas associated with these thalamic nuclei. The project brings the resources and the imaging/anatomical researchers of the Mount Sinai Department of ..
  22. Thalamic Glutamate Dysregulation in Schizophrenia
    James Meador Woodruff; Fiscal Year: 2007
    ..postsynaptic receptor complex, by measuring transcript and protein levels expressed in functionally distinct thalamic nuclei. Further, we will perform cell level studies that will permit comparisons of changes in mRNA expression by ..