septal nuclei

Summary

Summary: Neural nuclei situated in the septal region. They have afferent and cholinergic efferent connections with a variety of forebrain and brainstem areas including the hippocampus, the lateral hypothalamus, the tegmentum, and the amygdala. Included are the dorsal, lateral, medial, and triangular septal nuclei, septofimbrial nucleus, nucleus of diagonal band, nucleus of anterior commissure, and the nucleus of stria terminalis.

Top Publications

  1. ncbi Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxiety
    David L Walker
    Department of Psychiatry and Behavioral Sciences and The Center for Behavioral Neuroscience, Emory University School of Medicine, 1639 Pierce Drive, Suite 4000, Atlanta, GA 30322, USA
    Eur J Pharmacol 463:199-216. 2003
  2. ncbi Topography of projections from amygdala to bed nuclei of the stria terminalis
    H W Dong
    Neuroscience Program, University of Southern California, Los Angeles, CA 90089-2520, USA
    Brain Res Brain Res Rev 38:192-246. 2001
  3. doi A switch in the neuromodulatory effects of dopamine in the oval bed nucleus of the stria terminalis associated with cocaine self-administration in rats
    Michal Krawczyk
    Department of Anesthesiology and Perioperative Medicine, Center for Neuroscience Studies, Queen s University, Kingston, Ontario K7L 3N6, Canada
    J Neurosci 31:8928-35. 2011
  4. ncbi Juxtacapsular nucleus of the stria terminalis of the adult rat: extrinsic inputs, cell types, and neuronal modules: a combined Golgi and electron microscopic study
    Jorge Larriva-Sahd
    Instituto de Neurobiologia, Campus UNAM UAQ, Juriquilla, Queretaro, CP 76001 Qro, Mexico
    J Comp Neurol 475:220-37. 2004
  5. pmc Human bed nucleus of the stria terminalis indexes hypervigilant threat monitoring
    Leah H Somerville
    Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire, USA
    Biol Psychiatry 68:416-24. 2010
  6. pmc The bed nucleus of the stria terminalis mediates inter-individual variations in anxiety and fear
    Sevil Duvarci
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
    J Neurosci 29:10357-61. 2009
  7. ncbi Differential projections of dorsal raphe nucleus neurons to the lateral septum and striatum
    Maria Waselus
    Department of Neurosurgery, Thomas Jefferson University, Farber Institute for Neurosciences, 900 Walnut Street, Philadelphia, PA 19107, USA
    J Chem Neuroanat 31:233-42. 2006
  8. ncbi Basic organization of projections from the oval and fusiform nuclei of the bed nuclei of the stria terminalis in adult rat brain
    H W Dong
    Neuroscience Program, University of Southern California, Los Angeles, California 90089-2520, USA
    J Comp Neurol 436:430-55. 2001
  9. pmc Linking context with reward: a functional circuit from hippocampal CA3 to ventral tegmental area
    Alice H Luo
    Behavioral Neuroscience Section, Behavioral Neuroscience Research Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA
    Science 333:353-7. 2011
  10. pmc Consistency and diversity of spike dynamics in the neurons of bed nucleus of stria terminalis of the rat: a dynamic clamp study
    Attila Szucs
    BioCircuits Institute, University of California San Diego, La Jolla, California, United States of America
    PLoS ONE 5:e11920. 2010

Detail Information

Publications213 found, 100 shown here

  1. ncbi Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxiety
    David L Walker
    Department of Psychiatry and Behavioral Sciences and The Center for Behavioral Neuroscience, Emory University School of Medicine, 1639 Pierce Drive, Suite 4000, Atlanta, GA 30322, USA
    Eur J Pharmacol 463:199-216. 2003
    ....
  2. ncbi Topography of projections from amygdala to bed nuclei of the stria terminalis
    H W Dong
    Neuroscience Program, University of Southern California, Los Angeles, CA 90089-2520, USA
    Brain Res Brain Res Rev 38:192-246. 2001
    ..The functional significance of these projections is discussed with reference to what is known about the output of the bed nuclei...
  3. doi A switch in the neuromodulatory effects of dopamine in the oval bed nucleus of the stria terminalis associated with cocaine self-administration in rats
    Michal Krawczyk
    Department of Anesthesiology and Perioperative Medicine, Center for Neuroscience Studies, Queen s University, Kingston, Ontario K7L 3N6, Canada
    J Neurosci 31:8928-35. 2011
    ..This change was unique to voluntary intake of cocaine and maintained after a withdrawal period, suggesting a mechanism underlying the maintenance of cocaine self-administration and perhaps craving during drug-free periods...
  4. ncbi Juxtacapsular nucleus of the stria terminalis of the adult rat: extrinsic inputs, cell types, and neuronal modules: a combined Golgi and electron microscopic study
    Jorge Larriva-Sahd
    Instituto de Neurobiologia, Campus UNAM UAQ, Juriquilla, Queretaro, CP 76001 Qro, Mexico
    J Comp Neurol 475:220-37. 2004
    ..Additional neural interaction between Ju neurons utilizes gap junction-mediated electrotonic coupling...
  5. pmc Human bed nucleus of the stria terminalis indexes hypervigilant threat monitoring
    Leah H Somerville
    Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire, USA
    Biol Psychiatry 68:416-24. 2010
    ....
  6. pmc The bed nucleus of the stria terminalis mediates inter-individual variations in anxiety and fear
    Sevil Duvarci
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
    J Neurosci 29:10357-61. 2009
    ..Overall, this suggests that inter-individual variations in fear generalization and anxiety phenotype are determined by BNST influences on the amygdala and/or its targets...
  7. ncbi Differential projections of dorsal raphe nucleus neurons to the lateral septum and striatum
    Maria Waselus
    Department of Neurosurgery, Thomas Jefferson University, Farber Institute for Neurosciences, 900 Walnut Street, Philadelphia, PA 19107, USA
    J Chem Neuroanat 31:233-42. 2006
    ..Taken together with previous microdialysis studies, these results support the existence of distinct DRN-5-HT-forebrain projections that are differentially regulated by stress...
  8. ncbi Basic organization of projections from the oval and fusiform nuclei of the bed nuclei of the stria terminalis in adult rat brain
    H W Dong
    Neuroscience Program, University of Southern California, Los Angeles, California 90089-2520, USA
    J Comp Neurol 436:430-55. 2001
    ..These and other results suggest that the BSTov and BSTfu are basal telencephalic parts of a circuit that coordinates autonomic, neuroendocrine, and ingestive behavioral responses during stress...
  9. pmc Linking context with reward: a functional circuit from hippocampal CA3 to ventral tegmental area
    Alice H Luo
    Behavioral Neuroscience Section, Behavioral Neuroscience Research Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA
    Science 333:353-7. 2011
    ..This transsynaptic link between hippocampus and VTA appears to be an important substrate by which environmental context regulates goal-directed behavior...
  10. pmc Consistency and diversity of spike dynamics in the neurons of bed nucleus of stria terminalis of the rat: a dynamic clamp study
    Attila Szucs
    BioCircuits Institute, University of California San Diego, La Jolla, California, United States of America
    PLoS ONE 5:e11920. 2010
    ..The high degree of their dynamical diversity has implications to their cooperative dynamics and synchronization...
  11. ncbi Bed nucleus of the stria terminalis subregions differentially regulate hypothalamic-pituitary-adrenal axis activity: implications for the integration of limbic inputs
    Dennis C Choi
    Neuroscience Program and Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    J Neurosci 27:2025-34. 2007
    ....
  12. pmc The role of the posterior medial bed nucleus of the stria terminalis in modulating hypothalamic-pituitary-adrenocortical axis responsiveness to acute and chronic stress
    Dennis C Choi
    Neuroscience Program, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Psychoneuroendocrinology 33:659-69. 2008
    ..The data further suggest that acute versus chronic stress integration are subserved by different brain circuitry...
  13. ncbi Self-administration enhances excitatory synaptic transmission in the bed nucleus of the stria terminalis
    Eric C Dumont
    The Vollum Institute and Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97239, USA
    Nat Neurosci 8:413-4. 2005
    ..There was no effect when cocaine or food was delivered passively, suggesting that synaptic plasticity in this area is involved in reward-seeking behaviors...
  14. doi Role of the extended amygdala in short-duration versus sustained fear: a tribute to Dr. Lennart Heimer
    David L Walker
    Yerkes National Primate Center and the Center for Behavioral Neuroscience, Emory University, 954 Gatewood Drive, Atlanta, GA 30329, USA
    Brain Struct Funct 213:29-42. 2008
    ..The generality of this idea is illustrated by selective studies looking at context conditioning, social defeat, drug withdrawal and stress induced reinstatement...
  15. ncbi Differential expression of intrinsic membrane currents in defined cell types of the anterolateral bed nucleus of the stria terminalis
    Sayamwong E Hammack
    Department of Psychiatry and Behavioral Science, Center for Behavioral Neuroscience, Emory University, Atlanta, Georgia 30329, USA
    J Neurophysiol 98:638-56. 2007
    ..The functional relevance of each cell type is discussed in relation to prior anatomical studies, as well as how these currents may interact to modulate neuronal activity within the BNST(ALG)...
  16. ncbi Activation of ventral tegmental area cells by the bed nucleus of the stria terminalis: a novel excitatory amino acid input to midbrain dopamine neurons
    François Georges
    Laboratory for Neuromodulation and Behavior, Department of Psychiatry, Veterans Affairs Medical Center, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 22:5173-87. 2002
    ..These results reveal that inputs from the vBNST exert a strong excitatory influence on VTA DA neurons mediated by both NMDA and non-NMDA receptors...
  17. doi Dissociation of the morphological correlates of stress-induced anxiety and fear
    J M Pego
    Life and Health Sciences Research Institute ICVS, School of Health Sciences, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal
    Eur J Neurosci 27:1503-16. 2008
    ..In conclusion, this study shows that chronic stress impacts on BNST structure and function; its findings pertain to the modulation of emotional behaviour and the maladaptive response to stress...
  18. ncbi Does the bed nucleus of the stria terminalis mediate fear behaviors?
    D Treit
    Department of Psychology, University of Alberta, Edmonton, Canada
    Behav Neurosci 112:379-86. 1998
    ..However, BNST lesions produced none of these anti-fear effects; thus, its involvement in the behavioral expression of fear is questionable...
  19. pmc Protracted withdrawal from alcohol and drugs of abuse impairs long-term potentiation of intrinsic excitability in the juxtacapsular bed nucleus of the stria terminalis
    Walter Francesconi
    Molecular and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, California 92037, USA
    J Neurosci 29:5389-401. 2009
    ..Thus, changes in the intrinsic properties of jcBNST neurons mediated by chronic activation of the CRF system may contribute to the persistent emotional dysregulation associated with protracted withdrawal...
  20. pmc Role of the bed nucleus of the stria terminalis in the control of ventral tegmental area dopamine neurons
    Marion Jalabert
    INSERM, U862, Neurocentre Magendie, Pathophysiology of Synaptic Plasticity Group, Bordeaux, F 33000, France
    Prog Neuropsychopharmacol Biol Psychiatry 33:1336-46. 2009
    ..We will discuss how changes in the activity of BST neurons projecting to the VTA could participate in the development or exacerbation of psychiatric conditions such as drug addiction...
  21. pmc Serotonin transporter availability in the amygdala and bed nucleus of the stria terminalis predicts anxious temperament and brain glucose metabolic activity
    Jonathan A Oler
    Departments of Psychiatry, HealthEmotions Research Institute, University of Wisconsin Madison, 53719, USA
    J Neurosci 29:9961-6. 2009
    ..Collectively, these findings suggest that serotonergic modulation of neuronal excitability in the neural circuitry associated with anxiety mediates the developmental risk for affect-related psychopathology...
  22. pmc Inputs to the ventrolateral bed nucleus of the stria terminalis
    Jung Won Shin
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Comp Neurol 511:628-57. 2008
    ..In summary, the BSTvl receives inputs from a variety of brain sites implicated in hunger, salt and water intake, stress, arousal, and reward...
  23. ncbi Modulation of anxiety by mu-opioid receptors of the lateral septal region in mice
    Julie Le Merrer
    Laboratoire de Neurosciences Cognitives, CNRS UMR 5106, Universite Bordeaux I, Avenue des Facultes, 33405 Talence, France
    Pharmacol Biochem Behav 83:465-79. 2006
    ..Taken together, these results suggest that LS mu-opioid receptors participate to the modulation of anxiety...
  24. ncbi Reduction of arginine vasopressin binding sites in mouse lateral septum by treatment with 6-hydroxydopamine
    H Ishizawa
    Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institute of Mental Health, Bethesda, MD 20892
    Brain Res 507:189-94. 1990
    ..In contrast to the results with 6-hydroxydopamine, treatment of mice with 5,7-dihydroxytryptamine, to destroy serotonergic terminals, did not alter vasopressin binding in the lateral septum...
  25. pmc A transcriptomic analysis of type I-III neurons in the bed nucleus of the stria terminalis
    Rimi Hazra
    Department of Psychiatry and Division of Behavioral Neuroscience and Psychiatric Disorders, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA
    Mol Cell Neurosci 46:699-709. 2011
    ....
  26. pmc Bi-directional modulation of bed nucleus of stria terminalis neurons by 5-HT: molecular expression and functional properties of excitatory 5-HT receptor subtypes
    J D Guo
    Department of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA
    Neuroscience 164:1776-93. 2009
    ..Hence, modulation of 5-HT(7) receptor activity in the BNST(ALG) may offer a novel avenue for the design of anxiolytic medications...
  27. ncbi Lateral septal neuronal firing rate increases during proestrus-estrus in the rat
    C M Contreras
    Laboratorio de Neurofarmacologia, Instituto de Neuroetologia, Universidad Veracruzana, Mexico City, Mexico
    Physiol Behav 68:279-84. 2000
    ..It is concluded that the higher firing rate in neurons from the dorsal aspect of the LSN during proestrus-estrus, may be associated with an increased motivation to escape from a stressful situation...
  28. pmc Induction by kainate of theta frequency rhythmic activity in the rat medial septum-diagonal band complex in vitro
    Helen L Garner
    School of Biomedical Sciences, The Worsley Building, University of Leeds, Leeds LS2 9JT, UK
    J Physiol 564:83-102. 2005
    ..We conclude that kainate activation of neuronal circuitry in the MSDB is capable of synchronization of rhythmic activity in the MSDB, and that this may underlie the mechanism for phase-locking rhythmic burst activity in the MSDB in vivo...
  29. ncbi Effects of chronic stress on dendritic arborization in the central and extended amygdala
    Ajai Vyas
    National Centre for Biological Sciences, Tata Institute of Fundamental Research, UAS GKVK Campus, Bangalore 560065, India
    Brain Res 965:290-4. 2003
    ..While dendritic arborization in CeA neurons remains unaffected, it increases in BNST neurons after CIS. These results suggest a role for dendritic remodeling of BNST neurons in stress-induced facilitation of anxiety...
  30. ncbi Adaptation in patterns of c-fos expression in the brain associated with exposure to either single or repeated social stress in male rats
    M Martinez
    Department of Anatomy, and MRC Cambridge Centre for Brain Repair, University of Cambridge, UK
    Eur J Neurosci 10:20-33. 1998
    ..As in our previous studies of repeated restraint, modulation in the expression of c-fos following repeated stress is highly regionally specific, suggesting that differential neural processing is involved in adaptation to social stress...
  31. pmc Alcohol inhibits NR2B-containing NMDA receptors in the ventral bed nucleus of the stria terminalis
    Thomas L Kash
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Neuropsychopharmacology 33:1379-90. 2008
    ..Finally, we demonstrate that ethanol inhibits NMDARs in cells in the vBNST that project to the VTA, providing a direct means by which ethanol in the vBNST can modulate the dopaminergic system...
  32. ncbi Met-enkephalin immunoreactive neurons recruited by acute stress are innervated by axon terminals immunopositive for tyrosine hydroxylase and dopamine-alpha-hydroxylase in the anterolateral division of bed nuclei of the stria terminalis in the rat
    Tamas Kozicz
    University of Pecs, Medical Faculty, Department of Human Anatomy, Pecs, Szigeti ut 12, H 7624, Hungary
    Eur J Neurosci 16:823-35. 2002
    ..These interactions can be central in the modulatory control of the major stress regulatory pathway, the limbic hypothalamo-pituitary-adrenal axis...
  33. ncbi The lowest effective dose of fluoxetine in the forced swim test significantly affects the firing rate of lateral septal nucleus neurones in the rat
    C M Contreras
    Laboratorio de Neurofarmacologia, Instituto de Neuroetologia, Universidad Veracruzana, Veracruz, Mexico
    J Psychopharmacol 15:231-6. 2001
    ..05). In conclusion, the increased neuronal tiring rate of the LSN in the animals treated with a low dose of fluoxetine may be associated with an increased motivation to escape from the stressful situation that the forced swim represents...
  34. pmc Chronic stress increases pituitary adenylate cyclase-activating peptide (PACAP) and brain-derived neurotrophic factor (BDNF) mRNA expression in the bed nucleus of the stria terminalis (BNST): roles for PACAP in anxiety-like behavior
    Sayamwong E Hammack
    Department of Psychology, University of Vermont, Burlington, VT 05405, USA
    Psychoneuroendocrinology 34:833-43. 2009
    ....
  35. ncbi Effects of bed nucleus of the stria terminalis lesions on conditioned anxiety: aversive conditioning with long-duration conditional stimuli and reinstatement of extinguished fear
    Jaylyn Waddell
    Department of Psychology, University of Vermont, Burlington, VT, USA
    Behav Neurosci 120:324-36. 2006
    ..Results are consistent with behavioral and anatomical distinctions between fear and anxiety and with a behavior-systems view of defensive conditioning...
  36. ncbi Involvement of rat lateral septum-acetylcholine pressor system in central amygdaloid nucleus-emotional pressor circuit
    Yao Hua Li
    Department of Physiology and Pathophysiology, Health Science Center, Peking University, 100083, Beijing, People s Republic of China
    Neurosci Lett 323:60-4. 2002
    ....
  37. doi Allopregnanolone microinjected into the lateral septum or dorsal hippocampus reduces immobility in the forced swim test: participation of the GABAA receptor
    Juan Francisco Rodríguez-Landa
    Laboratorio de Neurofarmacologia, Instituto de Neuroetologia, Universidad Nacional Autonoma de Mexico, Xalapa, Veracruz, Mexico
    Behav Pharmacol 20:614-22. 2009
    ....
  38. doi A morphometric analysis of the septal nuclei in schizophrenia and affective disorders: reduced neuronal density in the lateral septal nucleus in bipolar disorder
    Ralf Brisch
    Department of Psychiatry, Otto von Guericke University of Magdeburg, Germany
    Eur Arch Psychiatry Clin Neurosci 261:47-58. 2011
    The septal nuclei are assumed to play a significant role in the pathophysiology of schizophrenia and affective disorders...
  39. pmc The response of neurons in the bed nucleus of the stria terminalis to serotonin: implications for anxiety
    Sayamwong E Hammack
    Department of Psychology, University of Vermont, 2 Colchester Avenue, John Dewey Hall, Burlington, VT 05405, USA
    Prog Neuropsychopharmacol Biol Psychiatry 33:1309-20. 2009
    ....
  40. ncbi Participation of the lateral septal nuclei (LSN) in the antidepressant-like actions of progesterone in the forced swimming test (FST)
    Erika Estrada-Camarena
    Instituto de Neuroetologia, Universidad Veracruzana, Xalapa Ver, Mexico
    Behav Brain Res 134:175-83. 2002
    The possible participation of lateral septal nuclei (LSN) in the antidepressant-like actions of progesterone was evaluated. The effect of different concentrations of progesterone (0.001, 0.01 and 0...
  41. ncbi Lesions in the bed nucleus of the stria terminalis disrupt corticosterone and freezing responses elicited by a contextual but not by a specific cue-conditioned fear stimulus
    G M Sullivan
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, 1051 Riverside Drive, Unit 41, New York, NY 10032, USA
    Neuroscience 128:7-14. 2004
    ..The results are also not consistent with the hypothesis that BNST is only involved in unconditioned aspects of fear and anxiety...
  42. ncbi Role of noradrenergic projections to the bed nucleus of the stria terminalis in the regulation of the hypothalamic-pituitary-adrenal axis
    María Inés Forray
    Department of Pharmacy, Faculty of Chemistry, Catholic University of Chile, Santiago, Chile
    Brain Res Brain Res Rev 47:145-60. 2004
    ....
  43. ncbi Androgens alter corticotropin releasing hormone and arginine vasopressin mRNA within forebrain sites known to regulate activity in the hypothalamic-pituitary-adrenal axis
    V Viau
    Department of Physiology, University of California, San Francisco 94143-0444, USA
    J Neuroendocrinol 13:442-52. 2001
    ....
  44. ncbi Chemical lesion of the bed nucleus of the stria terminalis blocks the behavioral consequences of uncontrollable stress
    Sayamwong E Hammack
    Department of Psychiatry, Emory University School of Medicine, Atlanta, GA 30322, USA
    Behav Neurosci 118:443-8. 2004
    ..BNST chemical lesion blocked the potentiation of freezing and the increases in escape latency that normally follow IS...
  45. ncbi Paternal behavior influences development of aggression and vasopressin expression in male California mouse offspring
    Cristianne R M Frazier
    Department of Zoology, University of Wisconsin Madison, USA
    Horm Behav 50:699-707. 2006
    ..This study provides further evidence that paternal behavior influences the development of aggression and associated neural substrates...
  46. ncbi Forebrain c-fos expression under conditions conducive to pair bonding in female prairie voles (Microtus ochrogaster)
    J Thomas Curtis
    Department of Psychology and Neuroscience Program, Florida State University, 209 Copeland Avenue, Tallahassee, FL 32306, USA
    Physiol Behav 80:95-101. 2003
    ..We suggest that areas that show evidence of fos expression after sufficient time for pair bonding to occur may be important in the formation of associations between the partner and mating stimuli...
  47. ncbi Histological and cytological study of the bed nuclei of the stria terminalis in adult rat. II. Oval nucleus: extrinsic inputs, cell types, neuropil, and neuronal modules
    Jorge Larriva-Sahd
    Instituto de Neurobiologia, UNAM, Juriquilla, Zona Centro Querétaro, CP 76001 Querétaro, Mexico
    J Comp Neurol 497:772-807. 2006
    ..The putative inputs from the major tracts of the forebrain coupled with the cytological organization of the Ov make it one of the most complex structures of the mammalian brain...
  48. ncbi Antidepressant-like and anxiolytic-like actions of the mGlu5 receptor antagonist MTEP, microinjected into lateral septal nuclei of male Wistar rats
    Miguel Molina-Hernandez
    Laboratorio de Psicobiología y Etología, Instituto de Investigaciones Psicologicas, Universidad Veracruzana, Jalapa, Veracruz, Mexico
    Prog Neuropsychopharmacol Biol Psychiatry 30:1129-35. 2006
    ..0 microg/microl; P<0.05) in the same brain area. It is concluded that intra-lateral septal infusions of the mGlu5 receptor antagonist MTEP produced antidepressant-like actions or anxiolytic-like effects in male rats...
  49. ncbi Norepinephrine modulates glutamatergic transmission in the bed nucleus of the stria terminalis
    Regula E Egli
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Neuropsychopharmacology 30:657-68. 2005
    ..Further experiments demonstrate that the actions of NE on glutamatergic transmission can be correlated with beta-AR function...
  50. ncbi Estrogen receptor-alpha distribution in male rodents is associated with social organization
    Bruce S Cushing
    The Brain Body Center, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Comp Neurol 494:595-605. 2006
    ....
  51. ncbi Long-term effects of a single exposure to immobilization: a c-fos mRNA study of the response to the homotypic stressor in the rat brain
    Astrid Vallès
    Departament de Biologia Cellular, de Fisiologia i d Immunologia, Unitat de Fisiologia Animal, Facultat de Ciències and Institut de Neurociènces, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    J Neurobiol 66:591-602. 2006
    ....
  52. ncbi Modulatory effects of galanin in the lateral bed nucleus of the stria terminalis on behavioral and neuroendocrine responses to acute stress
    Habibeh Khoshbouei
    Department of Pharmacology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Neuropsychopharmacology 27:25-34. 2002
    ..These results suggest that during stress, the neuropeptide galanin exerts a modulatory effect in the BSTL, facilitating behavioral and neuroendocrine components of the acute stress response...
  53. ncbi Organization of axonal projections from the anterolateral area of the bed nuclei of the stria terminalis
    Hong Wei Dong
    Neuroscience Program and Department of Biological Sciences, University of Southern California, Los Angeles, California 90089 2520, USA
    J Comp Neurol 468:277-98. 2004
    ..BSTal projections are distinct from those of the adjacent juxtacapsular, oval, fusiform, and rhomboid nuclei...
  54. ncbi Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration
    Brad A Grueter
    Department of Molecular Physiology, Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Neurosci 26:3210-9. 2006
    ....
  55. ncbi BNST lesions aggravate behavioral despair but do not impair navigational learning in rats
    Pinar Pezuk
    Psychobiology Laboratory, Department of Psychology, Bogazici University, 34342 Bebek, Istanbul, Turkey
    Brain Res Bull 69:416-21. 2006
    ..Experimentally induced depression by BNST lesions does not impair learning and memory in the water maze suggesting a possible dissociation between BNST-mediated depression and cognitive performance...
  56. ncbi Interactions of norepinephrine and galanin in the central amygdala and lateral bed nucleus of the stria terminalis modulate the behavioral response to acute stress
    David A Morilak
    Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas Health Science Center at San Antonio, MC 7764, 7703 Floyd Curl Drive, 78229 3900, USA
    Life Sci 73:715-26. 2003
    ..Thus, the interaction of galanin and norepinephrine may be a viable target for the future development of novel therapeutic strategies for treating behavioral disorders related to stress or drug abuse...
  57. ncbi Cardiovascular effects of carbachol microinjected into the bed nucleus of the stria terminalis of the rat brain
    F H F Alves
    Department of Pharmacology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil
    Brain Res 1143:161-8. 2007
    ..In conclusion, results suggest that microinjection of CBH in the BST activates local M(2)-muscarinic receptor evoking pressor and bradycardiac responses, which are mediated by acute vasopressin release into circulation...
  58. pmc Morphine produces circuit-specific neuroplasticity in the bed nucleus of the stria terminalis
    E C Dumont
    Department of Anesthesiology and Center for Neuroscience Studies, Queen s University, 99 University Avenue, Kingston, Ontario, Canada K7L 3N6
    Neuroscience 153:232-9. 2008
    ..Likewise, the inputs to neurons that did not project to the VTA were not changed by morphine. Altogether, these results extend the understanding of neuronal circuits intrinsically sensitive to drugs of abuse within the BST...
  59. pmc The bed nucleus of the stria terminalis modulates learning after stress in masculinized but not cycling females
    Debbie A Bangasser
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    J Neurosci 28:6383-7. 2008
    ..Importantly, together these studies indicate that males and females can engage different brain structures to modulate learning after a stressful experience...
  60. doi Effects of BNST lesions in female rats on forced swimming and navigational learning
    Pinar Pezuk
    Department of Biology, University of Virginia, Charlottesville, VA 22904 4328, USA
    Brain Res 1228:199-207. 2008
    ....
  61. doi Bed nucleus of the stria terminalis N-methyl-D-aspartate receptors and nitric oxide modulate the baroreflex cardiac component in unanesthetized rats
    Fernando H F Alves
    Department of Pharmacology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
    J Neurosci Res 87:1703-11. 2009
    ..In conclusion, our data point out that local NMDA and nNOS interaction mediates the tonic inhibitory influence of the BST on the baroreflex bradycardiac response, modulating the parasympathetic cardiac activity...
  62. pmc Both alpha1 and alpha2-adrenoceptors mediate the cardiovascular responses to noradrenaline microinjected into the bed nucleus of the stria terminal of rats
    C C Crestani
    Department of Pharmacology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil
    Br J Pharmacol 153:583-90. 2008
    ..In the present study, we investigated the subtype of adrenoceptors that mediates the cardiovascular response to noradrenaline microinjection into the BST...
  63. ncbi Modulatory effects of norepinephrine in the lateral bed nucleus of the stria terminalis on behavioral and neuroendocrine responses to acute stress
    M Cecchi
    Department of Pharmacology, MC 7764, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Neuroscience 112:13-21. 2002
    ....
  64. ncbi Microarray analysis reveals distinctive signaling between the bed nucleus of the stria terminalis, nucleus accumbens, and dorsal striatum
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Physiol Genomics 32:283-98. 2008
    ..Furthermore, these studies provide a framework for future mouse-mouse comparisons of transcriptional profiles after behavioral/pharmacological manipulation...
  65. doi Cannabinoid receptors in the bed nucleus of the stria terminalis control cortical excitation of midbrain dopamine cells in vivo
    Lema Massi
    Pathophysiology of Synaptic Plasticity Group, INSERM, U862, Neurocentre Magendie and Université de Bordeaux, Bordeaux, F 33000, France
    J Neurosci 28:10496-508. 2008
    ..Our data identify a new neuronal substrate for the actions of cannabinoids in the reward pathway...
  66. doi Anxiolytic-like effects induced by acute reversible inactivation of the bed nucleus of stria terminalis
    L B M Resstel
    Department of Pharmacology, School of Medicine of Ribeirao Preto, University of Sao Paulo, USP, Av Bandeirantes 3900, 14049 900, Ribeirao Preto, Sao Paulo, 14049 900, Brazil
    Neuroscience 154:869-76. 2008
    ..The results indicate that the BNST is engaged in behavioral responses elicited by punished stimuli and aversively conditioned contexts, reinforcing its proposed role in anxiety...
  67. pmc Intrinsic neuronal plasticity in the juxtacapsular nucleus of the bed nuclei of the stria terminalis (jcBNST)
    Walter Francesconi
    Molecular and Integrative Neurosciences Department, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, California 92037, USA
    Prog Neuropsychopharmacol Biol Psychiatry 33:1347-55. 2009
    ..These results provide a novel neurobiological target for vulnerability to alcohol and drug dependence...
  68. ncbi Group II and III metabotropic glutamate receptors suppress excitatory synaptic transmission in the dorsolateral bed nucleus of the stria terminalis
    Brad A Grueter
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Neuropsychopharmacology 30:1302-11. 2005
    ..In total, our data suggest a plausible site of action for some of the anxiolytic effects of group II and group III mGluR agonists...
  69. doi Bed nucleus of the stria terminalis alpha(1)-adrenoceptor modulates baroreflex cardiac component in unanesthetized rats
    Carlos C Crestani
    Department of Pharmacology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Av Bandeirantes 3900, 14049 900 Ribeirao Preto, São Paulo 14090 090, Brazil
    Brain Res 1245:108-15. 2008
    ..In conclusion, our data point out that local alpha(1)-adrenoceptors mediate the BST tonic influence on the baroreflex bradycardiac response modulating parasympathetic cardiac activity...
  70. doi Involvement of hypothalamic paraventricular nucleus non-N-methyl-D-aspartate receptors in the pressor response to noradrenaline microinjected into the bed nucleus of the stria terminalis of unanesthetized rats
    Carlos C Crestani
    Department of Pharmacology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Av Bandeirantes 3900, Ribeirao Preto, Sao Paulo 14049 900, Brazil
    Eur J Neurosci 29:2166-76. 2009
    ..They also suggest that a glutamatergic neurotransmission through non-NMDA glutamate receptors in the PVN mediates the response...
  71. ncbi Cardiovascular effects of noradrenaline microinjection in the bed nucleus of the stria terminalis of the rat brain
    C C Crestani
    Department of Pharmacology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
    J Neurosci Res 85:1592-9. 2007
    ..In conclusion, results indicate that microinjection of NA into the BST evokes pressor responses, which are mediated by acute vasopressin release...
  72. ncbi Vasopressin and aggression in cross-fostered California mice (Peromyscus californicus) and white-footed mice (Peromyscus leucopus)
    J K Bester-Meredith
    Department of Psychology, University of Wisconsin, 1202 W. Johnson Street, Madison, Wisconsin 53706, USA
    Horm Behav 40:51-64. 2001
    ....
  73. ncbi Involvement of GABAergic and cholinergic medial septal neurons in hippocampal theta rhythm
    Ryan M Yoder
    Department of Psychology, J P Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, Ohio 43403, USA
    Hippocampus 15:381-92. 2005
    ..We conclude that both GABAergic and cholinergic MSDB neurons are necessary for HPCtheta under urethane, and that each of these septohippocampal projections contributes to HPCtheta during locomotion...
  74. ncbi Differential excitatory responses to oxytocin in sub-divisions of the bed nuclei of the stria terminalis
    B C Wilson
    Department of Biology, Acadia University, 24 University Avenue, Wolfville, NS, Canada B4P 2R6
    Neuropeptides 39:403-7. 2005
    ..Thus, excitatory responses to oxytocin vary markedly between BST sub-divisions and may reflect associations within the extended amygdala...
  75. ncbi Galantamine-induced behavioral recovery after sublethal excitotoxic lesions to the rat medial septum
    Jan Mulder
    Department of Molecular Neurobiology, University of Groningen, Kerklaan 30, NL 9750 AA Haren, The Netherlands
    Behav Brain Res 163:33-41. 2005
    ..In conclusion, our data show that galantamine attenuates experimentally-induced cognitive impairments underscored by mild neuronal damage...
  76. ncbi Characterization of medial septal glutamatergic neurons and their projection to the hippocampus
    Luis V Colom
    Department of Biological Sciences, University of Texas at Brownsville Texas Southmost College, Brownsville, Texas
    Synapse 58:151-64. 2005
    ..Thus, the septo-hippocampal projection needs to be reconsidered as a three neurotransmitter pathway...
  77. ncbi Involvement of the bed nucleus of the stria terminalis activated by the central nucleus of the amygdala in the negative affective component of morphine withdrawal in rats
    T Nakagawa
    Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606 8501, Japan
    Neuroscience 134:9-19. 2005
    ..These results suggest that activation of the BST mediated through the neural pathway from the Ce contributes to the negative affective component of morphine withdrawal...
  78. ncbi Patterns of afferent projections to the dentate gyrus studied in organotypic co-cultures
    Kathleen M Guthrie
    Department of Anatomy and Neurobiology, College of Medicine, University of California, Irvine, CA 92697 1280, USA
    Brain Res Dev Brain Res 157:162-71. 2005
    ....
  79. ncbi Gonadal hormones act extrinsic to the hippocampus to influence the density of hippocampal astroglial processes
    T T Lam
    Department of Obstetrics and Gynecology, Yale University, School of Medicine, New Haven, CT 06520 8063, USA
    Neuroscience 116:491-8. 2003
    ..Furthermore, estradiol can have an indirect negative effect on hippocampal astrocytes, causing a reduction in the density of their processes...
  80. ncbi Mapping the neural circuit activated by alarm pheromone perception by c-Fos immunohistochemistry
    Yasushi Kiyokawa
    Laboratory of Veterinary Ethology, The University of Tokyo, 1 1 1 Yayoi, Bunkyo ku, Tokyo 113 8657, Japan
    Brain Res 1043:145-54. 2005
    ..e., an alarm pheromone, and suggest that the perception of the alarm pheromone is related to stress-responsive brains structures, including the hypothalamus and brainstem, as well as to the amygdaloid nuclei...
  81. ncbi Organization of immune-responsive medullary projections to the bed nucleus of the stria terminalis, central amygdala, and paraventricular nucleus of the hypothalamus: evidence for parallel viscerosensory pathways in the rat brain
    Ronald P A Gaykema
    Program in Sensory and Systems Neuroscience, Department of Psychology, P O Box 400400, University of Virginia, Charlottesville, VA 22904 4400, USA
    Brain Res 1130:130-45. 2007
    ....
  82. ncbi Functional mapping of the prosencephalic systems involved in organizing predatory behavior in rats
    E Comoli
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Avenida Lineu Prestes, 1524, CEP 05508 900 São Paulo, SP, Brazil
    Neuroscience 130:1055-67. 2005
    ..Moreover, the comparison with regular food intake contrasts putative neural mechanisms controlling predatory related eating vs. regular food intake...
  83. ncbi 5-HT1A receptor mRNA and immunoreactivity in the rat medial septum/diagonal band of Broca-relationships to GABAergic and cholinergic neurons
    M Luttgen
    Department of Neuroscience, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    J Chem Neuroanat 29:93-111. 2005
    ..In addition, 5-HT may exert its effects in the MSDB via cells expressing both 5-HT1A and 5-HT2A receptors...
  84. doi Types and synaptic connections of hippocampal inhibitory neurons reciprocally connected with the medial septum
    Virág T Takács
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, PO Box 67, H 1450 Hungary
    Eur J Neurosci 28:148-64. 2008
    ..oriens and radiatum. The synaptic organization suggests that by sampling the activity of large populations of principal cells HS cells can reliably broadcast hippocampal activity level to the medial septum...
  85. doi The hippocamposeptal pathway generates rhythmic firing of GABAergic neurons in the medial septum and diagonal bands: an investigation using a complete septohippocampal preparation in vitro
    Frédéric Manseau
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Quebec, Canada H4H 1R3
    J Neurosci 28:4096-107. 2008
    ..Our data demonstrate that hippocamposeptal inhibition facilitates theta rhythmic discharges in MS/DB GABAergic neurons while favoring the inhibition of most ACh and glutamate neurons...
  86. pmc Stereological estimates of the basal forebrain cell population in the rat, including neurons containing choline acetyltransferase, glutamic acid decarboxylase or phosphate-activated glutaminase and colocalizing vesicular glutamate transporters
    I Gritti
    Dipartimento di Scienze Cliniche Luigi Sacco, Universita degli Studi di Milano, Via Giovan Battista Grassi 74, Milan, Italy 20157
    Neuroscience 143:1051-64. 2006
    ....
  87. ncbi Neural interaction between galanin-like peptide (GALP)- and luteinizing hormone-releasing hormone (LHRH)-containing neurons
    Fumiko Takenoya
    Department of Anatomy I, Showa University School of Medicine, Tokyo 142 8555, Japan
    Peptides 27:2885-93. 2006
    ..These results strongly suggest that GALP-containing neurons provide direct input to LHRH-containing neurons and that GALP plays a crucial role in the regulation of LH secretion via LHRH...
  88. ncbi Evidence for a distinct group of nestin-immunoreactive neurons within the basal forebrain of adult rats
    S Wang
    Department of Anatomy and Neurobiology, Zhongshan Medical College, Sun Yat Sen University, 74 Zhongshan 2nd Road, Guangzhou, 510080 PR China
    Neuroscience 142:1209-19. 2006
    ....
  89. ncbi Group II metabotropic glutamate receptors in anxiety circuitry: correspondence of physiological response and subcellular distribution
    E Chris Muly
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia 30329, USA
    J Comp Neurol 505:682-700. 2007
    ..The combination of direct inhibition of projection neurons within the BLA and suppression of excitatory neurotransmission in the BNST may be responsible for the anxiolytic actions of group II mGluR agonists...
  90. ncbi The effect of atropine administered in the medial septum or hippocampus on high- and low-frequency theta rhythms in the hippocampus of urethane anesthetized rats
    Shaomin Li
    Laboratory of Neurophysiology, Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Synapse 61:412-9. 2007
    ....
  91. ncbi Differential c-fos expression in the brain of male Japanese quail following exposure to stimuli that predict or do not predict the arrival of a female
    M Taziaux
    Center for Cellular and Molecular Neurobiology, Research Group in Behavioural Neuroendocrinology, University of Liege, Belgium
    Eur J Neurosci 25:2835-46. 2007
    ..Further, these data suggest that conditioned and unconditioned sexual stimuli activate different brain regions but have similar behavioural consequences...
  92. pmc Forebrain neurons that project to the gustatory parabrachial nucleus in rat lack glutamic acid decarboxylase
    Shalini Saggu
    Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Am J Physiol Regul Integr Comp Physiol 294:R52-7. 2008
    ..If we assume that the influence of centrifugal input is mediated by direct projections to the gustatory region of the PBN, then GABAergic forebrain neurons apparently are not part of this descending pathway...
  93. pmc Environmental novelty is signaled by reduction of the hippocampal theta frequency
    A Jeewajee
    Department of Anatomy and Developmental Biology, University College London, United Kingdom
    Hippocampus 18:340-8. 2008
    ....
  94. pmc The memory-impairing effects of septal GABA receptor activation involve GABAergic septo-hippocampal projection neurons
    Desiree L Krebs-Kraft
    Department of Psychology, Georgia State University, Atlanta, Georgia 30303, USA
    Learn Mem 14:833-41. 2007
    ..Combined, these findings suggest that GABAergic SH projections are involved in the memory-impairing effects of septal GABA receptor activation...
  95. pmc Decreased immunoreactivity of the melanocortin neuropeptide alpha-melanocyte-stimulating hormone (alpha-MSH) after chronic ethanol exposure in Sprague-Dawley rats
    Montserrat Navarro
    Department of Psychology, University of North Carolina, Chapel Hill, North Carolina 27599 3270, USA
    Alcohol Clin Exp Res 32:266-76. 2008
    ..We also determined if ethanol exposure would alter the immunoreactivity of agouti-related protein (AgRP), an endogenous MCR antagonist...
  96. pmc Projections from bed nuclei of the stria terminalis, anteromedial area: cerebral hemisphere integration of neuroendocrine, autonomic, and behavioral aspects of energy balance
    Hong Wei Dong
    Department of Biological Sciences, University of Southern California, Los Angeles, 90089 2520, USA
    J Comp Neurol 494:142-78. 2006
    ....
  97. ncbi Galanin-mediated anxiolytic effect in rat central amygdala is not a result of corelease from noradrenergic terminals
    Gabe Barrera
    Department of Pharmacology and Center for Biomedical Neuroscience, University of Texas Health Science Center, San Antonio, 78229, USA
    Synapse 59:27-40. 2006
    ....
  98. ncbi Branching patterns of parabrachial neurons projecting to the central extended amgydala: single axonal reconstructions
    Maysa Sarhan
    Unité Mixte de Recherche 7519, Centre National de la Recherche Scientifique Université Louis Pasteur, 67084 Strasbourg, France
    J Comp Neurol 491:418-42. 2005
    ..This pPB-EAc pathway, which appears distinct from the parabrachiohypothalamic and parabrachiothalamic projections, would be the anatomical basis through which the EAc elaborates the autonomic, endocrine, and emotional components of pain...
  99. ncbi Input from the medial septum regulates adult hippocampal neurogenesis
    Karin Van der Borght
    Department of Molecular Neurobiology, Graduate School of Behavioural and Cognitive Neurosciences, University of Groningen, P O Box 14, 9750 AA Haren, The Netherlands
    Brain Res Bull 67:117-25. 2005
    ..The present study points out the importance of a functional septohippocampal pathway for the regulation of hippocampal neurogenesis and highlights the potential role of GABA as a mediator in this phenomenon...
  100. doi Alteration in [11C]vorozole binding to aromatase in neuronal cells of rat brain induced by anabolic androgenic steroids and flutamide
    Kayo Takahashi
    Molecular Probe Dynamics Laboratory, Molecular Imaging Research Program, RIKEN, Kobe, Japan
    Neuroreport 19:431-5. 2008
    ..This aromatase-specific tracer and the positron emission tomography technique could be useful for exploring the role of aromatase in anabolic androgenic steroids abusers...
  101. ncbi GABAB and CB1 cannabinoid receptor expression identifies two types of septal cholinergic neurons
    Gábor Nyiri
    Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Szigony u 43, Hungary
    Eur J Neurosci 21:3034-42. 2005
    ..The results also suggest that cholinergic transmission in the hippocampus is fine-tuned by endocannabinoid signalling...

Research Grants101 found, 100 shown here

  1. CONNECTIONS OF THE LIMBIC SYSTEM AND HYPOTHALAMUS
    LARRY SWANSON; Fiscal Year: 1993
    ..The circuitry under consideration may play an important role in the etiology of at least some forms of hypertension, obesity, diabetes, reproductive dysfunction, and clinical depression...
  2. The Lateral Septum, Urocortin and Alcohol
    ADAM WEITEMIER; Fiscal Year: 2004
    ..First, the effect of CRF receptor ligands microinjected into the CRF2 receptor-rich lateral septal nuclei (LS) on alcohol consumption will be investigated...
  3. Perinatal choline therapy in a mouse model of Down Syndrome & Alzheimer's Disease
    Barbara J Strupp; Fiscal Year: 2010
    ....
  4. Perinatal choline therapy in a mouse model of Down Syndrome & Alzheimer's Disease
    Barbara Strupp; Fiscal Year: 2009
    ....
  5. CENTER FOR THE STUDY OF EMOTION AND ATTENTION
    Peter Lang; Fiscal Year: 2007
    ..Finally, we will carry out brain imaging of odor-mediated fear retention, extinction, and conditioned inhibition in anesthetized rats usingfMRI in an 11 T magnet measured with blood pressure ..
  6. THE ROLE OF PREPROTRH PEPTIDES IN COCAINE ACTION
    Kevin Sevarino; Fiscal Year: 2004
    ..Further, acute cocaine caused significant regulation of TRH peptide levels in the nucleus accumbens, septal nuclei, and the hypothalamus, brain loci central to the limbic-motor circuit...
  7. METABOTROPIC GLUTAMATE RECEPTORS AND EXCITOTOXICITY
    Fang Zheng; Fiscal Year: 2007
    ..The findings will provide critical information for developing drugs that can be used to treat Parkinson's diseases, seizures, psychosis and excitotoxicity associated with stroke. ..
  8. Neuronal transport of gp120
    Italo Mocchetti; Fiscal Year: 2005
    ..gp120 into the caudate nucleus or fimbria and examine gp120 immunoreactivity in the substantia nigra and septal nuclei, respectively...
  9. ELECTROPHYSIOLOGY OF SENSORY GATING IN SCHIZOPHRENIA
    Robert Freedman; Fiscal Year: 1991
    ....
  10. Low-Dose Methylphenidate and the Prefrontal Cortex
    Craig W Berridge; Fiscal Year: 2010
    ....
  11. Mechanisms of Basal Forebrain Neurodegeneration
    LUIS COLOM; Fiscal Year: 2004
    ..Data from this work may contribute to the development of specific therapies designed to decrease neuronal dysfunction and vulnerability in AD. Furthermore, this work will contribute to our understanding of basal forebrain physiology. ..
  12. MBRS SCORE Program at the Univ of Texas-Brownsville
    LUIS COLOM; Fiscal Year: 2006
    ..The funding of these projects will substantially increase the competitiveness and research capabilities of UTB/TSC and will provide the foundation for developing a biomedical research center. ..
  13. MBRS SCORE Program at the Univ of Texas-Brownsville
    LUIS COLOM; Fiscal Year: 2007
    ..Furthermore, the success of this application will contribute to the development of internal collaborations and the necessary scientific environment to develop successful R01 applications in the near future. ..
  14. Aromatase regulation of paternal behavior and aggression
    BRIAN TRAINOR; Fiscal Year: 2002
    ..In summary, this proposal examines how aromatase mediates the effects of testosterone and social behavior. ..
  15. Environmental regulation of estrogen dependent aggression
    Brian C Trainor; Fiscal Year: 2010
    ..The proposed research will investigate the cellular mechanisms that underlie this gene-environment interaction that affects a behavior associated with many mental disorders. ..
  16. Environmental regulation of estrogen dependent aggression
    Brian C Trainor; Fiscal Year: 2011
    ..The proposed research will investigate the cellular mechanisms that underlie this gene-environment interaction that affects a behavior associated with many mental disorders. ..
  17. Estrogen receptors, photoperiod, and aggression
    BRIAN TRAINOR; Fiscal Year: 2007
    ..The proposed research should provide a novel and important framework to understand how the environment interacts with ER function to modulate behavior. ..
  18. Neural Substrates of Phasic versus Sustained Fear
    David L Walker; Fiscal Year: 2010
    ..Recent studies indicate that the neural substrates of short-duration fear responses may be different from those of more sustained fear responses. The experiments proposed herein are meant to further explore these differences. ..
  19. Convergent Versus Parallel Striatal Afferents
    Daniel S Zahm; Fiscal Year: 2010
    ....
  20. AFFERENT REGULATION OF CHOLINERGIC FOREBRAIN NEURONS
    Laszlo Zaborszky; Fiscal Year: 2007
    ..abstract_text> ..
  21. The Effect of Gonadal Steriods on Pavlovian Fear Conditioning
    Donna Toufexis; Fiscal Year: 2007
    ....
  22. CONVERGENT VS PARALLEL STRIATAL DOPAMINERGIC AFFERENTS
    DANIEL ZAHM; Fiscal Year: 1991
    ..In concert, the two components of the proposed investigation should contribute to bridging conceptual gaps separating structure and function in striatum...
  23. Psychosocial disruption of estradiol action on behavior
    Donna J Toufexis; Fiscal Year: 2010
    ..These studies will characterize mechanisms that may lead to the development of therapeutic interventions to prevent or minimize the adverse consequences of psychosocial stress on female emotional health. ..
  24. Psychosocial disruption of estradiol action on behavior
    Donna Toufexis; Fiscal Year: 2009
    ..These studies will characterize mechanisms that may lead to the development of therapeutic interventions to prevent or minimize the adverse consequences of psychosocial stress on female emotional health. ..
  25. ELEMENTARY SCHOOL NEUROSCIENCE LITERACY
    Gary Duncan; Fiscal Year: 2006
    ..The proposed work will pilot the program in schools with diverse demographics, to guide the development of resources and materials that will allow dissemination of the Brain Explorers program in a wide range of public school settings. ..
  26. Antipsychotic Actions in Models of NMDA Hypofunction
    Gary Duncan; Fiscal Year: 2007
    ....
  27. SENSORY CODING IN TASTE
    David Smith; Fiscal Year: 2000
    ....
  28. Perioculomotor area and alcohol
    Andrey Ryabinin; Fiscal Year: 2009
    ..These studies will provide novel important information indicating how these recently identified neurons robustly regulate alcohol intake. ..
  29. FUNCTIONAL ANATOMY OF LIMBIC-NEUROENDOCRINE CIRCUITS
    James Herman; Fiscal Year: 2006
    ..abstract_text> ..
  30. NEUROANATOMICAL SUBSTRATES OF ALCOHOL-INDUCED AMNESIA
    Andrey Ryabinin; Fiscal Year: 2001
    ..Taken together, these studies will provide valuable insight at several levels of analysis of alcohol~s action on cognitive functions and eventually allow to start understanding of the mechanisms involved in alcohol-induced amnesia. ..
  31. Exploratory Studies of Androgen Receptors in Axons
    Lydia Doncarlos; Fiscal Year: 2006
    ..abstract_text> ..
  32. Neural Analysis of Maternal Aggression
    STEPHEN GAMMIE; Fiscal Year: 2006
    ..Basic research into sex differences in aggression, then, is important to understanding the biological underpinnings of sex and gender differences in social behavior, health, and disease. ..
  33. Neurotransmission evoked by 5HT-dependent luminal factor
    Ying Li; Fiscal Year: 2005
    ..Finally, we will examine the roles of various neurotransmitters in the DMN in the mediation of pancreatic secretion stimulated by luminal 5HT-dependent factors using a conscious rat model. ..