parietal bone

Summary

Top Publications

  1. ncbi Cavernous hemangioma of the parietal bone. A case report
    A Ajja
    Departement of Neurosurgery, Mohammed V Military Hospital, Rabat, Morocco
    J Neurosurg Sci 49:159-62; discussion 162. 2005
  2. ncbi Tissue origins and interactions in the mammalian skull vault
    Xiaobing Jiang
    Institute for Genetic Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Dev Biol 241:106-16. 2002
  3. pmc The ALX4 homeobox gene is mutated in patients with ossification defects of the skull (foramina parietalia permagna, OMIM 168500)
    W Wuyts
    Department of Medical Genetics, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
    J Med Genet 37:916-20. 2000
  4. pmc Differential FGF ligands and FGF receptors expression pattern in frontal and parietal calvarial bones
    Natalina Quarto
    Children s Surgical Research Program, Department of Surgery, Stanford University School of Medicine, Stanford, Calif 94305 5148, USA
    Cells Tissues Organs 190:158-69. 2009
  5. ncbi Enlarged parietal foramina: MR imaging features in the fetus and neonate
    A M Fink
    Department of Medical Imaging, The Royal Children s Hospital, Flemington Road, Parkville, Melbourne 3052, Australia
    AJNR Am J Neuroradiol 27:1379-81. 2006
  6. ncbi Taking calvarial grafts, either split in situ or splitting of the parietal bone flap ex vivo--tools and techniques: V. A 9650-case experience in craniofacial and maxillofacial surgery
    P Tessier
    Miami Children s Hospital, Miami, FL 33155, USA
    Plast Reconstr Surg 116:54S-71S; discussion 92S-94S. 2005
  7. ncbi Bone augmentation by recombinant human BMP-2 and collagen on adult rat parietal bone
    M Murata
    Second Department of Oral Surgery, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Japan
    Int J Oral Maxillofac Surg 28:232-7. 1999
  8. ncbi Taking calvarial grafts--tools and techniques: VI. The splitting of a parietal bone "flap"
    P Tessier
    Miami Children s Hospital, Miami, FL 33155, USA
    Plast Reconstr Surg 116:74S-88S; discussion 92S-94S. 2005
  9. ncbi Parietal bone as graft material for maxillary sinus floor elevation: structure and remodeling of the donor and of recipient sites
    Ingrid Le Lorc'h-Bukiet
    Laboratoire de Biologie et Physiopathologie Cranio faciales, Groupe Physiopathologie Osseuse, Faculte de Chirurgie Dentaire, Universite, France
    Clin Oral Implants Res 16:244-9. 2005
  10. pmc Ultrasound insertion loss of rat parietal bone appears to be proportional to animal mass at submegahertz frequencies
    Meaghan A O'Reilly
    Imaging Research, Sunnybrook Research Institute, Toronto, Ontario, Canada
    Ultrasound Med Biol 37:1930-7. 2011

Detail Information

Publications210 found, 100 shown here

  1. ncbi Cavernous hemangioma of the parietal bone. A case report
    A Ajja
    Departement of Neurosurgery, Mohammed V Military Hospital, Rabat, Morocco
    J Neurosurg Sci 49:159-62; discussion 162. 2005
    ..A plain X-ray of the skull and cranial CT-scan showed a osteolytic lesion in the left parietal bone. Surgery consisted of total resection of the lesion and cranioplasty. The postoperative course was uneventful...
  2. ncbi Tissue origins and interactions in the mammalian skull vault
    Xiaobing Jiang
    Institute for Genetic Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Dev Biol 241:106-16. 2002
    ..These observations provide new perspectives on skull evolution and on human genetic abnormalities of skull growth and ossification...
  3. pmc The ALX4 homeobox gene is mutated in patients with ossification defects of the skull (foramina parietalia permagna, OMIM 168500)
    W Wuyts
    Department of Medical Genetics, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
    J Med Genet 37:916-20. 2000
    ....
  4. pmc Differential FGF ligands and FGF receptors expression pattern in frontal and parietal calvarial bones
    Natalina Quarto
    Children s Surgical Research Program, Department of Surgery, Stanford University School of Medicine, Stanford, Calif 94305 5148, USA
    Cells Tissues Organs 190:158-69. 2009
    ..aiming to highlight distinct differences between the neural crest-derived frontal and mesodermal-derived parietal bone. We performed a detailed comparative gene expression profile of FGF ligands and their receptors known to play ..
  5. ncbi Enlarged parietal foramina: MR imaging features in the fetus and neonate
    A M Fink
    Department of Medical Imaging, The Royal Children s Hospital, Flemington Road, Parkville, Melbourne 3052, Australia
    AJNR Am J Neuroradiol 27:1379-81. 2006
    ..We discuss its relationship to the spectrum of cephalocoeles...
  6. ncbi Taking calvarial grafts, either split in situ or splitting of the parietal bone flap ex vivo--tools and techniques: V. A 9650-case experience in craniofacial and maxillofacial surgery
    P Tessier
    Miami Children s Hospital, Miami, FL 33155, USA
    Plast Reconstr Surg 116:54S-71S; discussion 92S-94S. 2005
  7. ncbi Bone augmentation by recombinant human BMP-2 and collagen on adult rat parietal bone
    M Murata
    Second Department of Oral Surgery, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Japan
    Int J Oral Maxillofac Surg 28:232-7. 1999
    ..Carrier collagen not only plays a role in rhBMP-2 delivery, but also provides a cell anchorage for cell differentiation and remains as an artificial matrix in woven bone...
  8. ncbi Taking calvarial grafts--tools and techniques: VI. The splitting of a parietal bone "flap"
    P Tessier
    Miami Children s Hospital, Miami, FL 33155, USA
    Plast Reconstr Surg 116:74S-88S; discussion 92S-94S. 2005
  9. ncbi Parietal bone as graft material for maxillary sinus floor elevation: structure and remodeling of the donor and of recipient sites
    Ingrid Le Lorc'h-Bukiet
    Laboratoire de Biologie et Physiopathologie Cranio faciales, Groupe Physiopathologie Osseuse, Faculte de Chirurgie Dentaire, Universite, France
    Clin Oral Implants Res 16:244-9. 2005
    Particulate parietal bone is used for maxillary sinus floor elevation procedure prior to dental implant placement...
  10. pmc Ultrasound insertion loss of rat parietal bone appears to be proportional to animal mass at submegahertz frequencies
    Meaghan A O'Reilly
    Imaging Research, Sunnybrook Research Institute, Toronto, Ontario, Canada
    Ultrasound Med Biol 37:1930-7. 2011
    ..Measurements of ultrasound transmission through rat parietal bone at five frequencies (0.268 MHz, 0.841 MHz, 1.409 MHz, 1.972 MHz and 2...
  11. ncbi Malignant giant-cell tumor of the parietal bone: case report and review of the literature
    J Leonard
    Department of Neurosurgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neurosurgery 48:424-9. 2001
    ..Pagetic GCTs are less aggressive than GCTs that are not associated with Paget's disease...
  12. ncbi Cleidocranial dysplasia with severe parietal bone dysplasia: C-terminal RUNX2 mutations
    Michael L Cunningham
    Children s Craniofacial Center, Children s Hospital and Regional Medical Center, Seattle, Washington 98195 6320, USA
    Birth Defects Res A Clin Mol Teratol 76:78-85. 2006
    ..Despite the characterization of 67 unique mutations in 97 individual cases, and the availability of animal models, no obvious genotype-phenotype correlation has emerged...
  13. ncbi Cranial vault lymphoma
    Andrew L Horstman
    Section of Hematology, Gundersen Lutheran Medical Center, La Crosse, WI 54601, USA
    Haematologica 89:EIM06. 2004
  14. ncbi Statin collagen grafts used to repair defects in the parietal bone of rabbits
    R W K Wong
    Orthodontics, University of Hong Kong, Government of Hong Kong SAR, Hong Kong
    Br J Oral Maxillofac Surg 41:244-8. 2003
    ..Fifteen bone defects were created in the parietal bone of nine New Zealand White rabbits...
  15. ncbi Chondromyxoid fibroma of the parietal bone
    Ponnuswamy Karkuzhali
    Institute of Neurology, Madras Medical College, Chennai, Tamilnadu, India
    Neuropathology 25:84-8. 2005
    We report the case of an 11-year old girl who presented with an intracranial chondromyxoid fibroma arising from parietal bone. Chondromyxoid fibroma is a benign cartilaginous neoplasm, which can be easily mistaken for chondrosarcoma, ..
  16. ncbi Regional thickness of parietal bone in Korean adults
    Y S Jung
    Department of Oral and Maxillofacial Surgery, Oral Science Research Center, College of Dentistry, Yonsei University, Seoul, Korea
    Int J Oral Maxillofac Surg 32:638-41. 2003
    To clarify the clinical utility of the parietal bone graft in maxillofacial reconstruction, we performed an anatomical study by measuring the regional thickness of the parietal bone in 47 Korean adult dry skulls...
  17. ncbi Material properties of the inner and outer cortical tables of the human parietal bone
    Jill Peterson
    Department of Biomedical Sciences, Baylor College of Dentistry, Texas A and M University System Health Science Center, Dallas, Texas 75246, USA
    Anat Rec 268:7-15. 2002
    ..Few sites on either table had significant orientations of the axes of maximum stiffness. Despite this apparent randomness in orientation, almost all sites exhibited anisotropies equivalent to other parts of the skeleton...
  18. ncbi Bilateral peninsula-shaped linear craniectomy for mild degrees of craniosynostosis: indication, technique and long-term results
    Pamir Erdincler
    Department of Neurosurgery, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey
    J Craniomaxillofac Surg 32:64-70. 2004
    ..The goals of surgery in craniosynostosis are to reduce increased intracranial pressure and to achieve a good aesthetic result with minimal mortality and morbidity. A new type of strip craniectomy according to these principles is presented...
  19. ncbi Effects of the LactoSorb bioabsorbable plates on the craniofacial development of rabbits: direct morphometric analysis using linear measurements
    R P Cançado
    Graduate Program in Oral and Maxillofacial Surgery, Pontificia Universidade Catolica do Rio Grande do Sul, Av Ipiranga 6681, CEP 90619 900, Porto Alegre, RS, Brazil
    Int J Oral Maxillofac Surg 35:528-32. 2006
    ..Normal neonatal craniofacial growth of rabbits was affected by the use of bioabsorbable plates in this study. Further studies should be conducted to investigate whether these plates affect growth in human beings...
  20. ncbi Quantifying positional plagiocephaly: reliability and validity of anthropometric measurements
    Patricia A Mortenson
    Department of Occupational Therapy, British Columbia, Canada
    J Craniofac Surg 17:413-9. 2006
    ..31). Development of a stable and meaningful measurement system for the extent of plagiocephaly is needed to allow scientific studies of the natural history of plagiocephaly and effectiveness of interventions...
  21. ncbi Acquired unilateral coronal craniosynostosis
    Kevin A Brenner
    The Aesthetic and Plastic Surgery Institute, University of California, Irvine, CA 92868 3298, USA
    J Craniofac Surg 17:561-7. 2006
    ..The genesis and molecular biology of craniosynostosis are discussed; patient presentation and treatment are reviewed...
  22. ncbi [Coronal approach. Surgical technique]
    B Laure
    Service de Chirurgie Maxillo Faciale et Stomatologie, CHU de Tours, Hopital Trousseau, 37044 Tours
    Rev Stomatol Chir Maxillofac 104:341-6. 2003
    ..Many indications in maxillo-facial surgery require a coronal approach. We recall the main anatomic features and describe the surgical technique...
  23. ncbi Preformed acrylic cranial implants using fused deposition modeling: a clinical report
    Peter M Gronet
    National Naval Dental Center, Bethesda, MD, USA
    J Prosthet Dent 90:429-33. 2003
    ..This clinical report presents a method for the fabrication of cranial implants for 2 patients using anatomic modeling technology...
  24. ncbi Cranial vault reduction cranioplasty in children with hydrocephalic macrocephaly
    Michael J Sundine
    Aesthetic and Plastic Surgery Institute, University of California Irvine Medical Center, California 92868 3298, USA
    J Craniofac Surg 17:645-55. 2006
    ..All of the patients required at least one shunt revision following the procedure. We conclude that total cranial vault reshaping is safe and effective for the treatment of macrocephaly secondary to hydrocephalus...
  25. ncbi Quantitative and qualitative assessment of morphology in sagittal synostosis: mid-sagittal vector analysis
    Jeffrey R Marcus
    Centre for Craniofacial Care and Research, Division of Plastic Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    J Craniofac Surg 17:680-6. 2006
    ..The transverse dimension is not addressed in this single plane analysis; a more comprehensive application will require additional planes of analysis and the development of a normative database...
  26. ncbi Neurocranial suture autotransplantation and periosteal dura stripping to provide a passive growth site in craniosynostosis--a case report
    Maurice Y Mommaerts
    Cleft Palate and Craniofacial Anomalies Team, General Hospital St Jan, Bruges, Belgium
    J Craniomaxillofac Surg 31:202-8. 2003
    ..The behaviour of a neurocranial suture autograft in a plagiocephalic infant is described...
  27. ncbi Pyrexia after transcranial surgery
    Satoshi Takagi
    Australian Craniofacial Unit, Women s and Children s Hospital, North Adelaide, Australia
    J Craniofac Surg 17:202-4. 2006
    ..We conclude that this pyrexia should be considered to be a part of the normal physiological response to craniofacial surgery...
  28. ncbi Delayed degradation in a resorbable plating system
    Richard Mackool
    Institute of Reconstructive Plastic Surgery, New York University Medical Center, New York, NY, USA
    J Craniofac Surg 17:194-7; discussion 197-8. 2006
    ..The bone underlying the plates was depressed and irregular in contour when compared with the adjacent bone. Microscopic studies showed a giant cell foreign-body reaction with crystalline material present in the cell vacuoles...
  29. ncbi Late results after unicoronal craniosynostosis correction
    Peter J Anderson
    Australian Craniofacial Unit, Women s and Children s Hospital, 72, King William Road, North Adelaide, South Australia, SA 5006
    J Craniofac Surg 16:37-44. 2005
    ....
  30. ncbi [Free temporoparietal osteomuscular flap for cranioplasty]
    V Bouetel
    Service de Chirurgie Maxillo faciale, plastique, reconstructrice et esthetique, Centre Hospitalier Régional d Orléans La Source, 14, Avenue de l Hopital, 45067 Orleans Cedex 2, France
    Rev Stomatol Chir Maxillofac 106:22-6. 2005
    ..The purpose of this report was to illustrate the usefulness of the free temoroparietal osteomuscular flap in this particular situation...
  31. ncbi The sequence in appearance and disappearance of impressiones gyrorum cerebri and cerebelli
    Lovorka Grgurevic
    Department of Anatomy Drago Perovic, School of Medicine, University of Zagreb, Zagreb, Croatia
    Coll Antropol 28:849-55. 2004
    ..The intensity in appearance of juga is partly influenced by the increasing thickness of the diploe...
  32. doi Cranial growth after distraction osteogenesis of the craniosynostosis
    Yong Oock Kim
    Department of Plastic and Reconstructive Surgery, Institute of Human Tissue Restoration, Yonsei University College of Medicine Korea, Seoul, Korea
    J Craniofac Surg 19:45-55. 2008
    ..The corrected symmetry of asymmetric deformity was well maintained during a long-term follow-up period as well...
  33. ncbi Management of the large cranial osteoma: experience with 13 adult patients
    Y Izci
    Department of Neurosurgery, Maresal Cakmak Military Hospital, Erzurum, Turkey
    Acta Neurochir (Wien) 147:1151-5; discussion 1155. 2005
    ..Large osteomas are benign, slow-growing and rare neoplasms of the skull, which are usually asymptomatic but may need surgical resection...
  34. pmc Confocal laser scanning microscopic analysis of collagen scaffolding patterns in cranial sutures
    Stephen M Warren
    Institute of Reconstructive Plastic Surgery, New York University Medical Center, New York, NY, USA
    J Craniofac Surg 19:198-203. 2008
    ..8% versus 60.6%; P < 0.05). Moreover, the pathologically fusing suture contained a highly organized mineralizing orthogonal collagen lattice. This is the first analysis of collagen patterns in patent and fusing cranial sutures...
  35. ncbi Cranial anatomy of the spade-headed amphisbaenian Diplometopon zarudnyi (Squamata, Amphisbaenia) based on high-resolution X-ray computed tomography
    Jessica Anderson Maisano
    Jackson School of Geosciences, The University of Texas at Austin, Austin, Texas 78712, USA
    J Morphol 267:70-102. 2006
    ..The degree to which this mosaic of features reflects functional demands, shared ancestry, and/or convergence is unclear in the absence of a stable hypothesis of amphisbaenian phylogeny...
  36. ncbi [Symmetrical bilateral epidural hematoma after head injury in the mid parietooccipital region: case report]
    Masaru Idei
    Department of Neurosurgery, Chugoku Rousai Hospital, 1 5 1 Hiro Tagaya, Kure shi 737 0193, Japan
    No Shinkei Geka 32:379-82. 2004
    ..Simultaneous bilateral craniotomies and removal of the epidural hematomas would have contributed to obtaining the good result in this patient...
  37. ncbi Microscopic approach to craniosynostosis
    James E Baumgartner
    Division of Pediatric Surgery, Department of Surgery, Medical School, The University of Texas Health Science Center at Houston, Texas, USA
    J Craniofac Surg 16:997-1005. 2005
    ..The authors note that critical to this approach is the postoperative helmet therapy. Early results are encouraging...
  38. ncbi Neurocranial morphology and growth in Williams syndrome
    Stefan Axelsson
    Department of Orthodontics, Faculty of Dentistry, University of Oslo, Norway
    Eur J Orthod 27:32-47. 2005
    ..A flattening was seen in the superior aspect of the parietal bone in both WS males and females...
  39. ncbi Monostotic craniofacial fibrous dysplasia: the Turkish experience
    Sertac Yetiser
    Department of ORL and HNS, Gulhane Medical School, Ankara, Turkey
    J Craniofac Surg 17:62-7. 2006
    ..Because of its benign nature and decreased growth rate after adolescence, surgical treatment should be reserved for those with functional impairment or severe cosmetic disturbance...
  40. ncbi Early failure of absorbable plating in a patient with syndromic brachycephaly
    Matthew B Baker
    Department of Plastic Surgery, Vanderbilt University Medical Center, 2100 Pierce Avenue, Nashville, TN 37232, USA
    J Craniofac Surg 15:519-22; discussion 522. 2004
    ..The reoperative rates for cranial remodeling surgery at our institution and the possible causes for this failure are discussed...
  41. ncbi Nanostructural and nanomechanical properties of synostosed postnatal human cranial sutures
    Nayra Grau
    Tissue Engineering Laboratory M C 841, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Craniofac Surg 17:91-8; discussion 98-9. 2006
    ..7 +/- 0.2 MPa was significantly higher than the synostosed metopic suture at 0.5 +/- 0.1 MPa (P < 0.01). These data suggest that various synostosed cranial sutures may have different structural and mechanical characteristics...
  42. ncbi Giant cranial extradural primary fibroxanthoma: a case report
    Haydar Usul
    Department of Neurosurgery, Karadeniz Technical University School of Medicine, Trabzon TR 61080, Turkey
    Surg Neurol 63:281-4. 2005
    ..However, until 2003, only a few cases of primary fibroxanthoma have been reported. We report a giant fibroxanthoma destroying the lateral skull base unaccompanied by a systemic or metabolic disease...
  43. ncbi Asterion as a surgical landmark for lateral cranial base approaches
    Hulya Ucerler
    Department of Anatomy, Faculty of Medicine, Ege University, Izmir, Turkey
    J Craniomaxillofac Surg 34:415-20. 2006
    ..When approaching the posterior fossa and posterolateral cranial base, surface landmarks are helpful in locating the junction of the transverse and the sigmoid sinus...
  44. ncbi Modeling of scaphocephaly using superelastic titanium-nickel rings: a preliminary report
    Kazimierz Kobus
    University Clinic of Medical Academy in Wroclaw, Wroclaw, Poland
    J Craniofac Surg 18:504-10. 2007
    ..Observations made so far and good treatment results indicate purposefulness of discussed treatment continuation...
  45. ncbi 'Z-pattern' craniosynostosis: a novel presentation of trisutural fusion
    Rodney E Schmelzer
    Craniofacial Center, Medical City Dallas Hospital, Dallas, Texas, USA
    J Craniofac Surg 18:568-74. 2007
    ..In this small series, a two-staged procedure successfully normalized the calvarial dysmorphism, and early growth and development appear normal...
  46. ncbi A child with Saethre-Chotzen syndrome, sensorineural hearing loss, and a TWIST mutation
    Samson Lee
    Department of Otolaryngology at the University of Washington, Seattle, Washington 98159, USA
    Cleft Palate Craniofac J 39:110-4. 2002
    ..This case report describes a patient with Saethre-Chotzen syndrome caused by a mutation in the TWIST gene who exhibits a severe to profound sensorineural hearing loss...
  47. ncbi Ultrasound diagnosis of craniosynostosis
    Carolyn Miller
    Children s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Cleft Palate Craniofac J 39:73-80. 2002
    ..To retrospectively study prenatal ultrasound images of patients with craniosynostosis to determine the extent to which prenatal diagnosis is possible...
  48. ncbi Traumatic basilar artery occlusion caused by a fracture of the clivus--case report
    S Sato
    Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
    Neurol Med Chir (Tokyo) 41:541-4. 2001
    ..Cerebral angiography is recommended in a patient in a deep coma without massive brain contusion at the early stage of head injury to identify the possibility of vertebrobasilar artery occlusion in a clivus fracture...
  49. doi Definition of topographic organization of skull profile in normal population and its implications on the role of sutures in skull morphology
    Farhad Pirouzmand
    Division of Neurosurgery, University of Toronto, Sunnybrook Health Sciences Center, 2075 Bayview Avenue, Toronto, Ontario, Canada
    J Craniofac Surg 19:27-36. 2008
    ..These territories hinge on the coronal suture. Therefore, the coronal suture may play a dominant role in final skull configuration...
  50. doi Spring-assisted cranioplasty vs pi-plasty for sagittal synostosis--a long term follow-up study
    Per Windh
    Department of Plastic Surgery, Sahlgrenska University Hospital, Goteborg, Sweden
    J Craniofac Surg 19:59-64. 2008
    ..The spring group was superior with respect to blood loss, transfusion requirements, operative time, ICU time, recovery time, and total hospital stay...
  51. ncbi Oblique facial clefting associated with unicoronal synostosis
    C A MacKinnon
    Australian Craniofacial Unit, Women and Children's Hospital, and the University of Adelaide, South Australia
    J Craniofac Surg 12:227-31. 2001
    ..Craniosynostosis and oblique facial clefting presenting together in the same patient is a rare event. We present such a case, and detail the treatment plan to allow simultaneous correction of both deformities...
  52. ncbi The effect of neurocranial surgery on basicranial morphology in isolated sagittal craniosynostosis
    V B DeLeon
    Department of Cell Biology and Anatomy, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Cleft Palate Craniofac J 38:134-46. 2001
    ..The lack of change in the postoperative cranial base angle suggests that neurocranial surgery alleviates the occipital rotation and decreased cranial base angle described in the sagittal synostosis basicranium...
  53. doi The misdiagnosis of craniosynostosis as deformational plagiocephaly
    Yuan Liu
    Section of Plastic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, CT, USA
    J Craniofac Surg 19:132-6. 2008
    ..We present 4 clinical reports on patients in whom unilateral coronal craniosynostosis and lambdoid craniosynostosis were originally misdiagnosed as occipital deformational plagiocephaly and highlight individual structural distinctions...
  54. ncbi Of mice and mutations: phenotypic effects of the diabetic db/db and ob/ob mutations on the skull and teeth of mice
    M Atar
    Paediatric Dentistry, Barts and The Royal London Hospital, Queen Mary University, School of Medicine and Dentistry, London, UK
    Eur Arch Paediatr Dent 9:37-40. 2008
    ..To compare the phenotypic appearance of the skull bones and teeth of wild type C57BL/6J mice with that of diabetic leptin-deficient (ob/ob) and diabetic leptin receptordeficient (db/db) mice used as models for diabetes...
  55. doi Single suture craniosynostosis: diagnosis and imaging
    Jyri Hukki
    Department of Plastic Surgery, Cleft Palate and Craniofacial Centre Helsinki, Finland
    Front Oral Biol 12:79-90. 2008
    ..In this review we describe the range of isolated synostoses and show how these can lead to a variety of different morphological and functional abnormalities...
  56. doi The Bmp pathway in skull vault development
    Robert Maxson
    Department of Biochemistry and Molecular Biology, University of Southern California Keck School of Medicine, Los Angeles, California, USA
    Front Oral Biol 12:197-208. 2008
    ....
  57. doi Skull thickness in patients with skeletal deep bite
    P E Jacobsen
    Community Dental Service, Herlev, Denmark
    Orthod Craniofac Res 11:119-23. 2008
    ..The present study examines the skull thickness in patients with skeletal deep bite and compares it with the skull thickness in subjects with neutral occlusion and normal craniofacial morphology...
  58. doi Three-dimensional analysis system for orthognathic surgery patients with jaw deformities
    Masahiko Terajima
    Department of Orthodontics, Faculty of Dentistry, Kyushu University, Fukuoka, Japan
    Am J Orthod Dentofacial Orthop 134:100-11. 2008
    ..The purpose of this article was to introduce a new method for comparing 3-dimensional (3D) standard values of the maxillofacial skeletal and facial soft-tissue morphology before and after orthognathic surgery...
  59. ncbi Bone and suture regeneration in calvarial defects by e-PTFE-membranes and demineralized bone matrix and the impact on calvarial growth: an experimental study in the rat
    Nikolaos Mardas
    Department of Periodontology and Oral Gerontology, Royal Dental College, Faculty of Health Sciences, University of Aarhus, Denmark
    J Craniofac Surg 13:453-62; discussion 462-4. 2002
    ..The treatment of the defects with DBM alone or DBM combined with GTR resulted in craniosynostosis and reduced cranial growth...
  60. ncbi Management of nonsyndromic craniosynostosis
    G E Ghali
    Division of Oral and Maxillofacial Surgery, Louisiana State University School of Medicine, 1501 Kings Highway, Shreveport, LA 71130 3932, USA
    Atlas Oral Maxillofac Surg Clin North Am 10:1-41. 2002
    ..More recently, additional advances in pediatric anesthesia and biodegradable plating systems have improved the management of these complex craniomaxillofacial deformities...
  61. ncbi A new skull of early Homo from Dmanisi, Georgia
    Abesalom Vekua
    Georgian State Museum, Georgian Academy of Sciences, 3 Purtseladze Street, Tbilisi 380007, Georgia
    Science 297:85-9. 2002
    ..We suggest that the ancestors of the Dmanisi population dispersed from Africa before the emergence of humans identified broadly with the H. erectus grade...
  62. ncbi Complications associated with gradual cranial vault distraction osteogenesis for the treatment of craniofacial synostosis
    Yoshiyuki Yonehara
    Division of Plastic and Reconstructive Surgery, Teikyo University School of Medicine, Japan
    J Craniofac Surg 14:526-8. 2003
    ..Advanced bone was deformed in one patient. In another, the expansion device was exposed, resulting in a postoperative scar. Despite these complications, the cranium was successfully expanded in all patients...
  63. ncbi Inheritance of sutural pattern at the pterion in Rhesus monkey skulls
    Qian Wang
    Department of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Baylor College of Dentistry, Texas A and M University Health Science Center, Dallas, TX 75246, USA
    Anat Rec A Discov Mol Cell Evol Biol 288:1042-9. 2006
    ..species but not humans and some apes) was characterized by an articulation between the temporal bone and parietal bone. Articulation between the sphenoid and parietal bones (type SP) accounted for 14% of the specimens and was ..
  64. ncbi Longitudinal cephalometric standards for the neurocranium in Norwegians from 6 to 21 years of age
    Stefan Axelsson
    Department of Orthodontics, Faculty of Dentistry, University of Oslo, Blindern, Norway
    Eur J Orthod 25:185-98. 2003
    ..The cephalometric standards of the neurocranium established in this study can be used as a reference material in investigations of individuals with various craniofacial aberrations and syndromes...
  65. ncbi Reconstruction of the immature craniofacial skeleton with a carbonated calcium phosphate bone cement: interaction with bioresorbable mesh
    Joseph E Losee
    Division of Plastic Surgery, The Children s Hospital at Strong and the University of Rochester, Rochester, New York 14642, USA
    J Craniofac Surg 14:117-24. 2003
    ..Calcium phosphate cement may be safely used for craniofacial reconstruction in the presence of PLA implants without compromise to its biocompatibility, osteoconductivity, or remodeling capacity...
  66. ncbi Long-spanning resorbable plates in cranial vault reconstruction
    Barry L Eppley
    Division of Plastic Surgery, Indiana University School of Medicine, Indianapolis 46202, USA
    J Craniofac Surg 14:89-91. 2003
  67. ncbi Three-dimensional cranial expansion using distraction osteogenesis for oxycephaly
    Tetsuji Uemura
    Division of Plastic and Reconstructive Surgery, Saga Medical School, Nabeshima, Saga, Japan
    J Craniofac Surg 14:29-36. 2003
    ..We describe two oxycephaly cases and the surgical technique of three-dimensional cranial expansion using distraction osteogenesis...
  68. ncbi Preliminary results of standardized occipital advancement in the treatment of lambdoid synostosis
    Joachim E Zoller
    Department of Oral and Maxillofacial Surgery, Medical Centre, University of Cologne, Koln, Germany
    J Craniomaxillofac Surg 30:343-8. 2002
    ..Based on the concept of frontoorbital advancement, we used the occipital advancement in order to correct unilateral or bilateral lambdoid synostosis...
  69. ncbi Strabismus in unicoronal synostosis: ipsilateral or contralateral?
    Claire Macintosh
    Oxford Craniofacial Unit, Oxford Radcliffe Hospitals NHS Trust, John Radcliffe Hospital, Oxford, United Kingdom
    J Craniofac Surg 18:465-9. 2007
    ..0872). Anisometropia and astigmatism were found more frequently in the eye contralateral to the fused suture...
  70. ncbi Frontocranial remodeling without opening of frontal sinuses in a scaphocephalic adolescent: a case report
    Daniel Marchac
    Craniofacial Unit, Neurosurgical Pediatric Department, Hopital Necker Enfants Malades, Paris, France
    J Craniofac Surg 13:698-705. 2002
    ..The case of a 19-year-old young man, followed since childhood, who finally requested the correction, is presented and discussed...
  71. ncbi Clinical findings precede objective diagnostic testing in the identification of increased ICP in syndromic craniosynostosis
    Lisa R David
    North Carolina Center for Cleft and Craniofacial Deformities, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Craniofac Surg 13:676-80. 2002
    ..In cases such as these, long-term follow-up is essential because of the progressive nature of the disorder as well as the possibility of a recurrence of elevated intracranial pressure and a need for secondary decompressive surgery...
  72. ncbi Study of asymmetries of the cranial vault in plagiocephaly
    Amandine Besson
    Cranio Facial Morphology Laboratory, Faculty of Odontology, Hopital Roger Salengro, Lille, France
    J Craniofac Surg 13:664-9. 2002
    ..A study on a larger population would make it possible to confirm these hypotheses and put forward new ones. Prospects for development could relate to study of all asymmetry problems affecting the base of the skull and the face...
  73. ncbi Auditory ERPs reveal brain dysfunction in infants with plagiocephaly
    Polina Balan
    Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
    J Craniofac Surg 13:520-5; discussion 526. 2002
    ..In the current study we demonstrated, for the first time, that the central sound processing, as reflected by ERPs, is affected in children with plagiocephaly...
  74. ncbi Ultrasound in the diagnosis of craniosynostosis
    Jan Regelsberger
    Department of Neurosurgery, University Hospital, Hamburg, Germany
    J Craniofac Surg 17:623-5; discussion 626-8. 2006
    ..Sonography offers the potential to be a standard investigation for infants with head deformities suspecting a suture pathology and has been therefore integrated in our craniofacial outpatient clinic as a daily routine method...
  75. ncbi Surgical treatment of aplasia cutis congenita of the scalp associated with bilateral coronal synostosis
    Yuzo Komuro
    Department of Plastic Surgery, Juntendo University School of Medicine, Tokyo, Japan
    J Craniofac Surg 13:513-9. 2002
    ..During the second stage, the residual hairless scar was completely covered with hair-bearing scalp by tissue expansion and the residual skull defects were successfully reconstructed with split calvarial bone grafting...
  76. ncbi Cranial base fracture and rhino cerebrospinmal fluid leakage. A case report
    G Magliulo
    ENT Department G Ferreri, La Sapienza University, Rome IT taly
    An Otorrinolaringol Ibero Am 34:35-44. 2007
    ..Skull base fractures may involve various bone structure (petrous portion of temporal bone, ethmoid, sphenoid, parietal bone)...
  77. ncbi [The effects of cerebral metabolic activator and vasodilator on cochlear blood flow]
    H Morisaki
    Department of Otolaryngology, Nagoya University School of Medicine
    Nihon Jibiinkoka Gakkai Kaiho 97:1393-405. 1994
    ..For the measurement of CBF, part of the parietal bone was exposed. The tip of the probe connected to a laser Doppler flowmeter was placed over the area...
  78. ncbi Osteopontin expression in osteoblasts and osteocytes during bone formation under mechanical stress in the calvarial suture in vivo
    Mikihiko Morinobu
    Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
    J Bone Miner Res 18:1706-15. 2003
    ..Our results indicated that OPN expression was enhanced during the bone formation and that OPN would be one of the positive factors for the bone formation under mechanical stress...
  79. doi Biodegradation of Inion fast-absorbing biodegradable plates and screws
    H Wolfgang Losken
    Division of Plastic and Reconstructive Surgery, University of North Carolina at Chapel Hill, North Carolina 27599 7195, USA
    J Craniofac Surg 19:748-56. 2008
    ..Plates were applied to the frontal bone, over a bony defect of the parietal bone, to a nasal bone fracture, and inserted in the subcutaneous space over the occipital bone in thirty 6-week-old ..
  80. ncbi Primary skull lesions in the pediatric population: a 25-year experience
    Sarah E Gibson
    Division of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Arch Pathol Lab Med 131:761-6. 2007
    ..Previous studies of skull lesions in the pediatric population suggest that dermoid/epidermoid tumors are the most common childhood skull tumors...
  81. doi Aneurysmal bone cysts of the head and neck in pediatric patients: a case series
    Lorne Segall
    Department of Otolaryngology, Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Int J Pediatr Otorhinolaryngol 72:977-83. 2008
    ..To characterize aneurysmal bone cysts (ABCs) of the head and neck as seen at a tertiary care center...
  82. doi Big head? Bald head! Skull expansion: alternative model for the primary mechanism of AGA
    Paul J Taylor
    Orpington, Kent BR6 6LH, United Kingdom
    Med Hypotheses 72:23-8. 2009
    ..Studies of human cranial anatomy indicate that frontal and parietal bone growth can account for the development of the male pattern baldness (MPB) profile and the variations that can ..
  83. ncbi Biomechanical strain and morphologic changes with age in rat calvarial bone and sutures
    Reiko Shibazaki
    Department of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Baylor College of Dentistry, Texas A and M Health Science Center, Dallas, Texas 75266 0677, USA
    Plast Reconstr Surg 119:2167-78; 2179-81. 2007
    ..The role of calvarial sutures in transmitting biomechanical forces within the head is unclear...
  84. ncbi Unicoronal suture immobilization in the fetal rabbit
    M Y Mommaerts
    Division of Maxillo Facial Surgery, Department of Surgery and Cleft Palate and Craniofacial Anomalies Team, General Hospital St Jan, Bruges, Belgium
    J Craniofac Surg 15:192-9. 2004
    ..suture of 4 fetuses in each litter was immobilized with a polyglactin suture piercing the frontal and parietal bone plates. The remaining two fetuses were sham-operated...
  85. doi A case of extensive hyperostosis frontalis interna in an 87-year-old female human cadaver
    Ernest F Talarico
    Department of Anatomy and Cell Biology, Indiana University School of Medicine Northwest, Gary, Indiana 46408 1197, USA
    Clin Anat 21:259-68. 2008
    ..in a woman with extensive Type D hyperostosis of the frontal bone and a large hyperostotic nodule in the parietal bone with impingement on the precentral gyrus, distinguishing this from the common form of HFI...
  86. ncbi [Skull plasty to correct congenital craniosynostosis]
    Wei Min Shen
    Department of Plastic Surgery, Children s Hospital Affiliated to Nanjing Medical University, Nanjing 210008, China
    Zhonghua Zheng Xing Wai Ke Za Zhi 23:284-7. 2007
    ..To investigate the technique of skull reconstruction for the congenital craniosynostosis...
  87. doi Surgical management of a canine intracranial abscess due to a bite wound
    Ann L Bilderback
    Long Island Veterinary Specialists, Plainview, NY 11803, USA
    J Vet Emerg Crit Care (San Antonio) 19:507-12. 2009
    ..To describe the successful surgical management of a brain abscess in a dog secondary to bite wound...
  88. doi Anterior two-thirds calvarial remodelling: operative technique for the correction of metopic synostosis in toddlers
    Hyewon Paik
    Department of Plastic and Reconstructive Surgery, The Catholic University of Korea, College of Medicine, St Mary s Hospital, 62 Yeoido Dong, Yeongdeungpo gu, Seoul, Republic of Korea
    J Plast Reconstr Aesthet Surg 63:36-41. 2010
    ..This article presents a surgical technique used over 5 years to treat trigonocephalic toddlers in Korea...
  89. ncbi Histological study of experimental reconstructive materials for repair of lateral skull base and dura mater defects in dogs
    Li Shi
    Institute of Otorhinolaryngology, PLA General Hospital, Beijing, People s Republic of China
    Acta Otolaryngol 123:552-4. 2003
    ..In order to assess the reconstructive properties of fascia lata, superficial fascia lata and bone morphogenetic protein (BMP) in skull base surgery, lateral skull base bone and dura mater defect models were established in dogs..
  90. ncbi Three-dimensional computed tomography cephalometry of plagiocephaly: asymmetry and shape analysis
    D J Netherway
    Australian Craniofacial Institute, Women s and Children s Hospital, 72 King William Road, North Adelaide, SA 5006, Australia
    Cleft Palate Craniofac J 43:201-10. 2006
    ..To investigate facial asymmetry associated with both deformational and synostotic plagiocephaly and to identify variables based on skeletal landmarks that distinguish the conditions and quantify severity...
  91. ncbi Osteopontin deficiency enhances anabolic action of EP4 agonist at a sub-optimal dose in bone
    Norihiko Kato
    Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3 10 Kanda Surugadai 2 Chome, Tokyo, Japan
    J Endocrinol 193:171-82. 2007
    ..Importantly, OPN deficiency enhanced the direct anabolic action of EP4A locally injected onto the parietal bone in inducing new bone formation...
  92. ncbi Haemodynamic effects of lead(II) acetate, ethanol, and their combination in rats
    Gyorgy Ungvary
    Jozsef Fodor National Center for Public Health, Nagyvarad ter 2, Budapest 1096, Hungary
    Int Arch Occup Environ Health 75:S45-53. 2002
    ..The aim of the study was to analyse the haemodynamic background of the hypertension-inducing effect of lead and the role of alcohol effect in hypertension caused by lead...
  93. ncbi [Several variantes of transfacial approach to calvaria bases and subbasal space]
    Tarik Masic
    Klinika za maksilofacijalnu hirurgiju, Klinicki centar Univerziteta u Sarajevu
    Med Arh 61:142-5. 2007
    ....
  94. ncbi [Effects of sophoricoside and genistein on biological characteristics of osteoblasts]
    Yong Xu
    Department of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    Zhong Xi Yi Jie He Xue Bao 7:223-7. 2009
    ..To observe the effects of sophoricoside and genistein on the biological characteristics of osteoblasts...
  95. doi Antibodies to dynorphin a (1-17) attenuate closed head injury induced blood-brain barrier disruption, brain edema formation and brain pathology in the rat
    H S Sharma
    Laboratory of Cerebrovascular Research, Department of Surgical Science, Anesthesiology and Intensive Care Medicine, University Hospital, Uppsala, Sweden
    Acta Neurochir Suppl 106:301-6. 2010
    ..The CHI was produced by an impact of 0.224 N on the right parietal bone under anesthesia by dropping a weight of 114.6 g on the skull from a height of 20 cm through a guide tube...
  96. doi Evaluation of craniofacial effects during rapid maxillary expansion through combined in vivo/in vitro and finite element studies
    C G Provatidis
    School of Mechanical Engineering, National Technical University of Athens, Athens, Greece
    Eur J Orthod 30:437-48. 2008
    ..Maximum displacements were observed in the area of maxilla below the hard palate, from the central incisors to second premolars, which dissipated at the frontal and parietal bone and nullified at the occipital bone.
  97. doi Unusual involvement of scalp and bilateral kidneys in an aggressive mediastinal diffuse large B cell lymphoma: documentation by FDG-PET imaging
    Sandip Basu
    Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India
    Clin Nucl Med 34:638-41. 2009
    ..months later, he returned with complaints of soft tissue swelling over the scalp; one of them in the high parietal bone and the other over the occipital region...
  98. doi Paleolithic hominin remains from Eshkaft-e Gavi (southern Zagros Mountains, Iran): description, affinities, and evidence for butchery
    Jeremiah E Scott
    School of Human Evolution and Social Change, Institute of Human Origins, Arizona State University, Tempe, AZ 85287 4101, USA
    J Hum Evol 57:248-59. 2009
    ..These cutmarked specimens, along with a fragment of parietal bone, are also burned...
  99. ncbi Fibroblast growth factor-2 augments recombinant human bone morphogenetic protein-2-induced osteoinductive activity
    Eiji Tanaka
    Department of Orthodontics and Craniofacial Developmental Biology, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan
    Ann Biomed Eng 34:717-25. 2006
    ..male rats of 8-week-old (prepubertal) and 16-week-old (postpubertal) received bone defects bilaterally in the parietal bone and the defects were filled by a polylactic acid polyglycolic acid copolymer/gelatin sponge (PGS) impregnated ..
  100. ncbi On the report of the first successful surgical treatment of brain abscess in the Ottoman Empire by Dr. Cemil Topuzlu in 1891
    Melike Mut
    Department of Neurosurgery, Institute for Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey
    Neurosurgery 61:869-72; discussion 872. 2007
    ..a sharp trauma resulting in a 15 cm-long scalp laceration and underlying linear cranial fracture in the right parietal bone. Dr...
  101. doi Effect of use of slow release of bone morphogenetic protein-2 and transforming growth factor-Beta-2 in a chitosan gel matrix on cranial bone graft survival in experimental cranial critical size defect model
    Halil Ibrahim Canter
    Acibadem University Faculty of Medicine, Department of Plastic, Reconstructive and Aesthetic Surgery, Acibadem Health Group, Acibadem Bakirkoy Hospital, Plastic, Reconstructive and Aesthetic Surgery Craniomaxillofacial Surgery, Halit Ziya Usakligil Cad No 1 Bakirkoy, 34140 Istanbul, Turkey
    Ann Plast Surg 64:342-50. 2010
    ..Bone density of the applied scaffold and the parietal bone at the same computed tomography section were measured in Hounsfield scale and this ratio was used for ..

Research Grants71

  1. Regional differences in neural crest and mesodermal derived calvarial bone healin
    Michael T Longaker; Fiscal Year: 2010
    ..observed the frontal bone to possess superior osteogenic potential both in vitro and in vivo compared to the parietal bone. Our proposal aims to verify this difference in osteogenic potential and elucidate the role of fibroblast ..
  2. MECHANISMS OF CORTISOL ACTION IN BONE
    Ernesto Canalis; Fiscal Year: 1993
    ..in cultures of 21 day fetal rat calvariae and of osteoblast-enriched (Ob) cells from 22 day fetal rat parietal bone. Cortisol also inhibited IGF II binding to Ob cells...
  3. In vivo function and tolerance to Factor VIII variants
    Brendan Lee; Fiscal Year: 2009
    ....
  4. Molecular Regulation of Ocular Gland Development
    Venkatesh Govindarajan; Fiscal Year: 2007
    ..In addition, the proposed studies will, in the long-term, allow the development of novel therapeutic approaches for treatment of patients with dry eye syndromes. ..
  5. Androgen action in bone: Overexpression of AR
    Kristine M Wiren; Fiscal Year: 2010
    ..These studies will identify specific molecular events/pathways influenced by androgen treatment in bone, and should lead to an improved understanding of mechanisms that influence adult bone size and quality. ..
  6. TWIST AND Msx2 IN BOUNDARY FORMATION AND CRANIOSYNOSTOSIS
    Robert Maxson; Fiscal Year: 2007
    ..neural crest-derived mesenchyme that forms the frontal bone and mesodermal-derived mesenchyme that forms the parietal bone. In an effort to identify other genes that function together with Twist in coronal suture development, we have ..
  7. Dysregulation of 3-prolyl-hydroxylation in Human Skeletal Dysplasias
    Brendan Lee; Fiscal Year: 2007
    ..e., the in vivo phenotypic and biochemical consequences of dysregulation of the 3-prolyl-hydroxylation machinery. ..
  8. Regulation of parietal bone differentiation
    Venkatesh Govindarajan; Fiscal Year: 2007
    ..Our preliminary results support the hypothesis that this switch in the parietal bone differentiation program is due to Fgf9 transgene expression in the cranial mesenchymal precursors...
  9. In vivo function and tolerance to Factor VIII variants
    BRENDAN HL LEE; Fiscal Year: 2011
    ..abstract_text> ..
  10. Argininosuccinate Lyase is an essential regulator of systemic nitric oxide produc
    BRENDAN HL LEE; Fiscal Year: 2010
    ..We will determine whether inhibiting ASL may be the most effective way for controlling NO production in diseases affecting the brain, heart, and pancreas. ..
  11. TWIST AND Msx2 IN BOUNDARY FORMATION AND CRANIOSYNOSTOSIS
    Robert E Maxson; Fiscal Year: 2010
    ..neural crest-derived mesenchyme that forms the frontal bone and mesodermal-derived mesenchyme that forms the parietal bone. In an effort to identify other genes that function together with Twist in coronal suture development, we have ..
  12. Molecular Regulation of Ocular Gland Development
    Venkatesh Govindarajan; Fiscal Year: 2010
    ..In addition, the proposed studies will, in the long-term, allow the development of novel therapeutic approaches for treatment of patients with dry eye syndromes. ..
  13. PHENOGENETICS OF SKULL AND BRAIN INTEGRATION IN CRANIOSYNOSTOSIS
    JOAN RICHTSMEIER; Fiscal Year: 2009
    ....
  14. Cellular and Molecular Mechanisms of Patterned Growth of the Mammalian Skull
    Robert E Maxson; Fiscal Year: 2010
    ..There, in response to unknown cues they coalesce into the frontal and parietal bone rudiments and expand apically, ultimately coming into apposition with their paired counterparts...
  15. PHENOGENETICS OF SKULL AND BRAIN INTEGRATION IN CRANIOSYNOSTOSIS
    JOAN THERESE RICHTSMEIER; Fiscal Year: 2010
    ....
  16. TWIST AND Msx2 IN BOUNDARY FORMATION AND CRANIOSYNOSTOSIS
    Robert Maxson; Fiscal Year: 2009
    ..neural crest-derived mesenchyme that forms the frontal bone and mesodermal-derived mesenchyme that forms the parietal bone. In an effort to identify other genes that function together with Twist in coronal suture development, we have ..
  17. Twist1 in Boundary Formation and Craniosynostosis
    Robert E Maxson; Fiscal Year: 2010
    ..In the long term, this work may help to devise new treatments of such birth defects. ..
  18. Differential Gene Expression in the Cochlear Nucleus
    David Friedland; Fiscal Year: 2007
    ..These data will also provide a powerful template upon which to test and design novel treatments for improving hearing, discrimination and tinnitus in a significant portion of the population. ..
  19. Persistent changes in brain expression after withdrawal
    KRISTINE WIREN; Fiscal Year: 2003
    ..e. physical dependence leading to withdrawal seizures) are regulated at the genetic level. This knowledge may help in the development of new strategies for the treatment of alcohol dependence. ..
  20. TRANSCRIPTIONAL REGULATORS IN CHONDROGENESIS
    Brendan Lee; Fiscal Year: 2002
    ....
  21. EXPRESSION AND FUNCTION OF MAMMALIAN HOMEOBOX GENES
    Robert Maxson; Fiscal Year: 2001
    ..3 gene activated by homologous recombination will be used to isolate such cells. Chimeric mice will be produced from these ES cells and bred to generate mice heterozygous and homozygous for the inactivated Hox 1.3 gene. ..
  22. ENTERAL PRECURSORS FOR UREA SYNTHESIS IN HUMANS
    Brendan Lee; Fiscal Year: 2006
    ..In addition it is anticipated that the results will benef it other individuals who have compromised protein metabolism. ..
  23. EXPRESSION & FUNCTION OF HOMEOBOX GENES
    Robert Maxson; Fiscal Year: 2006
    ..In addition, we will test the hypothesis that loss of Msx2 function resulting from loss of regulability of Msx2 by Twist contributes to the calvarial foramen defect in Twist mutant mice. ..
  24. Adenoviral hepatocyte gene therapy in Citrullinemia
    Brendan Lee; Fiscal Year: 2005
    ..The data from these studies would be widely applicable to gene replacement therapy in a host of intrinsic disorders of liver metabolism as well as deficiencies of secretory proteins. ..
  25. Dysregulation of 3-prolyl-hydroxylation in Human Skeletal Dysplasias
    BRENDAN HL LEE; Fiscal Year: 2010
    ..e., the in vivo phenotypic and biochemical consequences of dysregulation of the 3-prolyl-hydroxylation machinery. ..
  26. GENETIC & ENVIRONMENTAL DETERMINANTS OF CRANIOFACIAL DIS
    Brendan Lee; Fiscal Year: 2005
    ..Together, these studies will identify genes important in pathogenesis of human malformation and elucidate their modes of action in both cell autonomous and cell non-autonomous models mechanisms of development. ..
  27. Transcriptional Regulation of Craniofacial Skeletogenesis
    Brendan Lee; Fiscal Year: 2009
    ....