Genomes and Genes
Summary: The SKELETON of the HEAD including the FACIAL BONES and the bones enclosing the BRAIN.
Publications191 found, 100 shown here
- New directions in craniofacial morphogenesisHeather L Szabo-Rogers
Department of Craniofacial Development, King s College London, UK SE1 9RT
Dev Biol 341:84-94. 2010..These and future studies will improve our understanding of the genetic and environmental influences underlying human craniofacial anomalies...
- Motor threshold in transcranial magnetic stimulation: the impact of white matter fiber orientation and skull-to-cortex distanceTal Herbsman
Mood Disorders Program and Brain Stimulation Laboratory, Department of Psychiatry, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Hum Brain Mapp 30:2044-55. 2009..We also measured the skull-to-cortex distance over the left motor region...
- Basal tyrannosauroids from China and evidence for protofeathers in tyrannosauroidsXing Xu
Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing 100044, China
Nature 431:680-4. 2004..One of the specimens also preserves a filamentous integumentary covering similar to that of other coelurosaurian theropods from western Liaoning. This provides the first direct fossil evidence that tyrannosauroids had protofeathers...
- Cranial design and function in a large theropod dinosaurE J Rayfield
Department of Earth Sciences, University of Cambridge, UK
Nature 409:1033-7. 2001..Here we have applied this technique to the long skull of the large carnivorous theropod dinosaur Allosaurus fragilis...
- Anatomy and taxonomic status of the chasmosaurine ceratopsid Nedoceratops hatcheri from the upper Cretaceous Lance Formation of Wyoming, U.S.AAndrew A Farke
Raymond M Alf Museum of Paleontology, Claremont, California, United States of America
PLoS ONE 6:e16196. 2011The validity of Nedoceratops hatcheri, a chasmosaurine ceratopsid dinosaur known from a single skull recovered in the Lance Formation of eastern Wyoming, U.S.A., has been debated for over a century...
- Facial heights: evolutionary relevance of postnatal ontogeny for facial orientation and skull morphology in humans and chimpanzeesMarkus Bastir
Department of Paleobiology, Museo Nacional de Ciencias Naturales, CSIC, 28006 Madrid, Spain
J Hum Evol 47:359-81. 2004..and inferior limits of facial compartments, contribute to the orientation of the viscerocranium in the primate skull. In humans, vertical facial variation is among the main sources of diversity and frequently associated with an ..
- Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R) miceYingli Wang
Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, USA
BMC Dev Biol 10:22. 2010..We previously reported an inbred transgenic mouse model with the Fgfr2 +/S252W mutation on the C57BL/6J background for Apert syndrome. Here we present a mouse model for the Fgfr2+/P253R mutation...
- Combined finite element and multibody dynamics analysis of biting in a Uromastyx hardwickii lizard skullM Moazen
Department of Engineering, University of Hull, Hull, UK
J Anat 213:499-508. 2008Lizard skulls vary greatly in shape and construction, and radical changes in skull form during evolution have made this an intriguing subject of research...
- Thinned-skull cranial window technique for long-term imaging of the cortex in live miceGuang Yang
Molecular Neurobiology Program, Department of Physiology and Neuroscience, Skirball Institute, New York University School of Medicine, New York, New York, USA
Nat Protoc 5:201-8. 2010..Here we describe in detail a protocol for imaging cortical structures at high optical resolution through a thinned-skull cranial window in live mice using two-photon laser scanning microscopy (TPLSM)...
- A basal alvarezsauroid theropod from the early Late Jurassic of Xinjiang, ChinaJonah N Choiniere
Department of Biological Sciences, The George Washington University, Washington, DC 20052, USA
Science 327:571-4. 2010..The new taxon confirms extreme morphological convergence between birds and derived alvarezsauroids and illuminates incipient stages of the highly modified alvarezsaurid forelimb...
- Large-scale diversification of skull shape in domestic dogs: disparity and modularityAbby Grace Drake
Faculty of Life Sciences, University of Manchester, Manchester, UK
Am Nat 175:289-301. 2010..We use geometric morphometrics to quantify the diversity of skull shape in 106 breeds of domestic dog, in three wild canid species, and across the order Carnivora...
- Form and function of damselfish skulls: rapid and repeated evolution into a limited number of trophic nichesW James Cooper
Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA
BMC Evol Biol 9:24. 2009..were used to describe patterns of morphological diversity and determine positions of functional groups in a skull morphospace...
- Genetic analysis of skull shape variation and morphological integration in the mouse using interspecific recombinant congenic strains between C57BL/6 and mice of the mus spretus speciesGaétan Burgio
Unité postulante de Génétique fonctionnelle de la Souris, CNRS URA 2578, Institut Pasteur, 75724 Paris Cedex 15, France
Evolution 63:2668-86. 2009To assess the genetic basis of the skull shape variation and morphological integration in mice, we have used a tool based on the cross between the distantly related mouse species Mus spretus (SEG/Pas strain) and the laboratory strain ..
- Cranial performance in the Komodo dragon (Varanus komodoensis) as revealed by high-resolution 3-D finite element analysisKaren Moreno
School of Biological, Earth and Environmental Sciences, University of New South Wales, Australia
J Anat 212:736-46. 2008..Its delicate 'space-frame' skull morphology differs greatly from that apparent in most living large prey specialists and is suggestive of a high ..
- Landmark-based shape analysis of the archaic Homo calvarium from Ceprano (Italy)Emiliano Bruner
Dipartimento di Biologia Animale e dell Uomo, Universita La Sapienza, Rome, Italy
Am J Phys Anthropol 132:355-66. 2007..In fact, despite the fact that the skull appears partially distorted by diagenetic pressures (thus precluding a comprehensive landmark-based analysis), ..
- New insights into craniofacial morphogenesisJill A Helms
Department of Plastic and Reconstructive Surgery, Stanford University, Stanford, CA 94305, USA
Development 132:851-61. 2005..Changes in craniofacial architecture also lie at the heart of evolutionary adaptation, as new studies in fish and fowl attest. Together, these findings reveal much about molecular and tissue interactions behind craniofacial development...
- Controversies in skull reconstructionJames E Zins
Department of Plastic Surgery, Cleveland Clinic, Cleveland, Ohio, USA
J Craniofac Surg 21:1755-60. 2010In the early 1980s, it was shown that bone from the skull (membranous bone) maintained its volume to a significantly greater extent than bone from the rib and iliac crest regions (endochondral bone)...
- Skull deformitiesEmily B Ridgway
Department of Neurological Surgery, New York University School of Medicine, 317 East 34 th Street, New York, NY 10016, USA
Pediatr Clin North Am 51:359-87. 2004..Because the most common causes of distortion or asymmetry are craniosynostosis or deformation, these abnormalities are the primary subjects of this article...
- Use of bone SPECT in the evaluation of fibrous dysplasia of the skullTadaki Nakahara
Department of Radiology, School of Medicine, Keio University, Tokyo, Japan
Clin Nucl Med 29:554-9. 2004
- Endocranial shape asymmetries in Pan paniscus, Pan troglodytes and Gorilla gorilla assessed via skull based landmark analysisAntoine Balzeau
Equipe de Paléontologie Humaine, CNRS, UMR 7194, Département de Préhistoire du Muséum national d histoire naturelle, Paris, France
J Hum Evol 59:54-69. 2010..Moreover, the detailed analysis of the 3D structure of these petalias reveals shared features, as well as features that are unique to the different great ape species...
- Allometry and performance: the evolution of skull form and function in felidsG J Slater
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA90095 1606, USA
J Evol Biol 22:2278-87. 2009Allometric patterns of skull-shape variation can have significant impacts on cranial mechanics and feeding performance, but have received little attention in previous studies...
- Fgfr mRNA isoforms in craniofacial bone developmentD P C Rice
Developmental Biology Programme, Institute of Biotechnology, University of Helsinki, Helsinki, Finland
Bone 33:14-27. 2003..Fgfr4 transcripts were found in developing muscles. These data help to explain the disturbances in craniofacial growth exhibited by both patients and the growing number of transgenic mice carrying mutations in genes encoding FGFRs/Fgfrs...
- Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox geneT Lufkin
Laboratoire de Genetique Moleculaire des Eucaryotes du CNRS, Institut de Chimie Biologique, Faculte de Medecine, Strasbourg, France
Nature 359:835-41. 1992..2. These results are similar to the homeotic posteriorization phenomenon generated in Drosophila by ectopic expression of genes of the homeotic complex HOM-C (refs 7-10; reviewed in ref. 3)...
- The giant crocodyliform Sarcosuchus from the Cretaceous of AfricaP C Sereno
Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA
Science 294:1516-9. 2001..The skull has an expansive narial bulla and elongate jaws studded with stout, smooth crowns that do not interlock...
- Evaluation of inverse methods and head models for EEG source localization using a human skull phantomS Baillet
Cognitive Neuroscience and Brain Imaging Laboratory, CNRS UPR640 LENA, H pital de la Salpêtrière, Paris, France
Phys Med Biol 46:77-96. 2001We used a real-skull phantom head to investigate the performances of representative methods for EEG source localization when considering various head models...
- A basal troodontid from the Early Cretaceous of ChinaXing Xu
Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing 100044, China
Nature 415:780-4. 2002..The discovery of Sinovenator and the examination of character distributions along the maniraptoran lineage indicate that principal structural modifications toward avians were acquired in the early stages of maniraptoran evolution...
- A cranium for the earliest Europeans: phylogenetic position of the hominid from Ceprano, ItalyG Manzi
Istituto Italiano di Paleontologia Umana, Rome, Italy
Proc Natl Acad Sci U S A 98:10011-6. 2001..Alternatively, a new species-ancestral to later European and African hominines-should be named to accommodate such a unique fossil specimen...
- Molecular origins of rapid and continuous morphological evolutionJohn W Fondon
Eugene McDermott Center for Human Growth and Development and Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390 8591, USA
Proc Natl Acad Sci U S A 101:18058-63. 2004..transcription factor 2) genes were quantitatively associated with significant differences in limb and skull morphology...
- Differences in matrix composition between calvaria and long bone in mice suggest differences in biomechanical properties and resorption: Special emphasis on collagenT Van den Bos
Department of Periodontology, Academic Center for Dentistry Amsterdam, Universiteit van Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands
Bone 43:459-68. 2008..Our data demonstrate considerable differences in protein composition of flat and long bones and strongly suggest functional differences in formation, resorption, and mechanical properties of these bone types...
- Frontal sinuses and head-butting in goats: a finite element analysisAndrew A Farke
Department of Anatomical Sciences, Stony Brook University, NY 11794 8081, USA
J Exp Biol 211:3085-94. 2008..This is consistent with the hypothesis that sinuses result at least in part from the removal of mechanically unnecessary bone...
- Epigenetic control of skull morphogenesis by histone deacetylase 8Michael Haberland
Department of Molecular Biology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
Genes Dev 23:1625-30. 2009..Here we provide evidence that Hdac8 specifically controls patterning of the skull by repressing a subset of transcription factors in cranial neural crest cells...
- MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnoverK Holmbeck
MMP Unit, National Institute of Dental and Craniofacial Research, Bethesda, Maryland 20892, USA
Cell 99:81-92. 1999....
- Rigid-body analysis of a lizard skull: modelling the skull of Uromastyx hardwickiiM Moazen
Centre for Medical Engineering and Technology, University of Hull, Hull, East Yorkshire HU6 7RX, UK
J Biomech 41:1274-80. 2008..Theoretical models and practical studies have posited a definite relationship between skull morphology and bite performance, but this can be difficult to demonstrate in vivo...
- SOX3 activity during pharyngeal segmentation is required for craniofacial morphogenesisKarine Rizzoti
Division of Developmental Genetics, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
Development 134:3437-48. 2007..They also give insight into the formation of pharyngeal pouches, of which little is known in vertebrates. Finally, this work introduces two new players in craniofacial development - SOX3 and SOX2...
- Cioclovina (Romania): affinities of an early modern EuropeanKaterina Harvati
Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig, Germany
J Hum Evol 53:732-46. 2007..Our results show Cioclovina to be entirely modern in its cranial shape, and do not support the hypothesis that it represents a hybrid...
- On the phylogenetic position of the pre-Neandertal specimen from Reilingen, GermanyD Dean
Department of Neurological Surgery, Case Western Reserve University, Cleveland, Ohio 44106, USA
J Hum Evol 34:485-508. 1998..e., "classic" Neandertals)...
- Fluid flow induction of cyclo-oxygenase 2 gene expression in osteoblasts is dependent on an extracellular signal-regulated kinase signaling pathwaySunil Wadhwa
Department of Orthodontics, School of Dental Medicine, University of Connecticut Health Center, Farmington 06030, USA
J Bone Miner Res 17:266-74. 2002..We conclude that FSS transcriptionally induces COX-2 gene expression in osteoblasts, that the maximum induction requires new protein synthesis, and that induction occurs largely via an ERK signaling pathway...
- Modularity in the skull and cranial vasculature of laboratory mice: implications for the evolution of complex phenotypesHeather A Jamniczky
Department of Cell Biology and Anatomy, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, Canada T2N 4Z6
Evol Dev 13:28-37. 2011..Here we use geometric morphometrics to investigate modularity in the arterial Circle of Willis (CW) and skull of the CD-1 laboratory mouse...
- Shape at the cross-roads: homoplasy and history in the evolution of the carnivoran skull towards herbivoryB Figueirido
Departamento de Ecología y Geología, Área de Paleontología, Facultad de Ciencias, Universidad de Malaga, Malaga, Spain
J Evol Biol 23:2579-94. 2010Patterns of skull shape in Carnivora provide examples of parallel and convergent evolution for similar ecomorphological adaptations...
- Langerhans cell histiocytosis of the skull on cytologic squash preparationsTadao K Kobayashi
Department of Pathology, Saiseikai Shiga Hospital, Imperial Gift Foundation Inc, Ritto, Shiga, Japan
Diagn Cytopathol 35:154-7. 2007We present a case in which a primary cytodiagnosis of Langerhans cell histiocytosis (LCH) of the skull was made using squash preparations...
- Allometry in the distribution of material properties and geometry of the felid skull: why larger species may need to change and how they may achieve itUphar Chamoli
Computational Biomechanics Research Group, Evolution and Ecology Research Centre, School of Biological, Earth and Environmental Sciences, University of New South Wales, Kensington Campus, Sydney, NSW 2052, Australia
J Theor Biol 283:217-26. 2011..e., despite great differences in size, there is relatively little variation in either the shape of the felid skull and dentition across species, or in the way in which these structures are used to kill and dismember prey...
- An unusual marine crocodyliform from the Jurassic-Cretaceous boundary of PatagoniaZulma Gasparini
Departamento de Paleontología de Vertebrados, Facultad de Ciencias Naturales y Museo, Universidad Nacional de La Plata, Paseo del Bosque s n, 1900 La Plata, Argentina
Science 311:70-3. 2006..Dakosaurus andiniensis from western South America reveal a lineage that drastically deviated from the skull morphology that characterizes marine crocodyliforms...
- CT-based description and phyletic evaluation of the archaic human calvarium from Ceprano, ItalyEmiliano Bruner
Dipartimento di Biologia Animale e dell'Uomo, , Rome, Italy
Anat Rec A Discov Mol Cell Evol Biol 285:643-58. 2005..Nevertheless, a proper taxonomic interpretation of this crucial specimen remains puzzling...
- Effect of measurement noise and electrode density on the spatial resolution of cortical potential distribution with different resistivity values for the skullOuti R M Ryynänen
Ragnar Granit Institute, Tampere University of Technology, Finland
IEEE Trans Biomed Eng 53:1851-8. 2006..noise and the number of electrodes on the spatial resolution with different resistivity ratios for the scalp, skull and brain...
- Major cranial changes during Triceratops ontogenyJohn R Horner
Museum of the Rockies, Montana State University, Bozeman, MT 59717 0040, USA
Proc Biol Sci 273:2757-61. 2006..Our analysis is based on a growth series of 10 skulls, ranging from a 38 cm long baby skull to about 2 m long adult skulls...
- Skeletal height reconstruction from measurements of the skull in indigenous South AfricansI Ryan
School of Anatomical Sciences, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
Forensic Sci Int 167:16-21. 2007..these bones are not always available for forensic analysis, it became necessary to use other bones such as the skull for stature estimation...
- Longitudinal and shear mode ultrasound propagation in human skull boneP J White
Department of Radiology, Harvard Medical School, Brigham and Women s Hospital, Boston, MA 02115, USA
Ultrasound Med Biol 32:1085-96. 2006..the idea of the longitudinal mode being the only significant mode of ultrasound energy transport through the skull bone...
- Skull-stripping magnetic resonance brain images using a model-based level setAudrey H Zhuang
Laboratory of Neuroimaging, Department of Neurology, University of California-Los Angeles, Los Angeles, CA 90095, USA
Neuroimage 32:79-92. 2006The segmentation of brain tissue from nonbrain tissue in magnetic resonance (MR) images, commonly referred to as skull stripping, is an important image processing step in many neuroimage studies...
- Trophy heads from Nawinpukio, Perú: physical and chemical analysis of Huarpa-era modified human remainsBrian Clifton Finucane
Research Laboratory for Archaeology and the History of Art, Oxford University, Oxford OX1 3QY, UK
Am J Phys Anthropol 135:75-84. 2008..Drawing on the formal properties of the specimens as well as ethnographic and archaeological analogies, it is suggested that the cranial basin served as a vessel for liquid...
- A euprimate skull from the early Eocene of ChinaXijun Ni
Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing 100044, China
Nature 427:65-8. 2004..Here we describe a partially preserved euprimate skull with nearly complete upper and lower dentition, which represents a new species of Teilhardina and constitutes the ..
- Surgical treatment of skull fibrous dysplasiaPeng Lei
Department of Neurosurgery, Lanzhou General Hospital, PR China
Surg Neurol 72:S17-20. 2009Fibrous dysplasia of the skull is difficult to manage when the cranial nerves, skull base, and face are involved...
- Morphological integration of the skull in craniofacial anomaliesJ T Richtsmeier
Department of Anthropology, Pennsylvania State University, University Park, PA 16802, USA
Orthod Craniofac Res 12:149-58. 2009..how surgical interventions impact the organization and internal integration of the major components of the skull, we address the functional and developmental relationships during perinatal development...
- Brain-skull contact boundary conditions in an inverse computational deformation modelSongbai Ji
Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
Med Image Anal 13:659-72. 2009..Although the significance of brain-skull boundary conditions (BCs) in these models has been explored in dynamic simulations, it has not been fully ..
- Comparative feeding biomechanics of Lystrosaurus and the generalized dicynodont OudenodonSandra C Jasinoski
Department of Earth Sciences, University of Bristol, Bristol BS8 1RJ, United Kingdom
Anat Rec (Hoboken) 292:862-74. 2009..Muscle forces were estimated for each dicynodont using the dry skull method and applied to each cranium to produce a reaction force at a bite point...
- Vestibular evoked myogenic potentials in response to lateral skull taps are dependent on two different mechanismsKrister Brantberg
Department of Audiology, Karolinska Hospital, 171 76 Stockholm, Sweden
Clin Neurophysiol 120:974-9. 2009To explore the mechanisms for skull tap induced vestibular evoked myogenic potentials (VEMP).
- Funerary practices of the Iberomaurusian population of Taforalt (Tafoughalt, Morocco, 11-12,000 BP): the case of Grave XIIMaria Giovanna Belcastro
Laboratorio di Bioarcheologia ed Osteologia Forense, Antropologia, Dipartimento di Biologia Evoluzionistica Sperimentale, Universita di Bologna, via Selmi, 3, 40126 Bologna, Italy
J Hum Evol 58:522-32. 2010..This study further supports our previous impression of the complex and diversified funerary practices, characterising the social life of the Iberomaurusian population of Taforalt...
- There is no heterotic effect upon developmental stability in the ventral side of the skull within the house mouse hybrid zoneO Mikula
Laboratory of Mammalian Evolutionary Biology, Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic, Brno, Czech Republic
J Evol Biol 21:1055-67. 2008..We studied patterns of FA in the ventral side of the skull along a transect across the central-European portion of the hybrid zone between two house mouse subspecies, Mus ..
- Comparative effects of scaffold pore size, pore volume, and total void volume on cranial bone healing patterns using microsphere-based scaffoldsCaren E Petrie Aronin
Department of Biomedical Engineering, University of Virginia, Charlottesville, USA
J Biomed Mater Res A 89:632-41. 2009..These results suggest that pore size and closed void volume may both play important roles in scaffold degradation patterns and associated bone healing...
- Predicting skull loading: applying multibody dynamics analysis to a macaque skullNeil Curtis
Centre for Medical Engineering and Technology, University of Hull, Hull, United Kingdom
Anat Rec (Hoboken) 291:491-501. 2008..study describes the novel use of MDA to investigate the influence of different muscle representations on a macaque skull model (Macaca fascicularis), where muscle groups were represented by either a single, multiple, or wrapped muscle ..
- The pace of morphological change: historical transformation of skull shape in St Bernard dogsAbby Grace Drake
Faculty of Life Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK
Proc Biol Sci 275:71-6. 2008..Here we use the methods of geometric morphometrics to study change of skull shape in a series of purebred St Bernard dogs spanning nearly 120 years...
- Comparison between in vivo and theoretical bite performance: using multi-body modelling to predict muscle and bite forces in a reptile skullN Curtis
Department of Engineering, University of Hull, Hull HU67RX, United Kingdom
J Biomech 43:2804-9. 2010..Here, using a sophisticated multi-body computer model of a reptile skull (the rhynchocephalian Sphenodon), we assess the accuracy of muscle force predictions by comparing predicted bite ..
- The intriguing history of the human calvaria: sinister and religiousR Shane Tubbs
Section of Pediatric Neurosurgery, Children s Hospital, Birmingham, AL 35233, USA
Childs Nerv Syst 24:417-22. 2008..For example, the purported site of Jesus' crucifixion "Calvary" is derived from this term calvaria. The present report explores the derivation, misuse, and history of the human calvaria...
- Towards building a photo-realistic virtual human face for craniomaxillofacial diagnosis and treatment planningA F Ayoub
University of Glasgow Dental School, Glasgow, UK
Int J Oral Maxillofac Surg 36:423-8. 2007..The registration errors between most parts of the aligned surfaces were within +/-1.5mm. The errors were relatively large around the eyebrows, eyelids and cheeks. Simultaneous recording of the face and skull may reduce this error.
- Relationship between thoracic, lordotic, and pelvic inclination and craniofacial morphology in adultsCarsten Lippold
Department of Orthodontics, University of Munster, Munster, Germany
Angle Orthod 76:779-85. 2006..To analyze the correlation ratios between the spinal posture (thoracic, lordotic, and pelvic inclination) and the craniofacial morphology...
- The craniofacial characteristics of osteogenesis imperfecta patientsPei Ching Chang
Department of Pediatric Dentistry, Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
Eur J Orthod 29:232-7. 2007....
- The craniofacial phenotype of the Crouzon mouse: analysis of a model for syndromic craniosynostosis using three-dimensional MicroCTChad A Perlyn
Division of Plastic Surgery, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
Cleft Palate Craniofac J 43:740-8. 2006To characterize the craniofacial phenotype of a mouse model for Crouzon syndrome by a quantitative analysis of skull morphology in mutant and wild-type mice and to compare the findings with skull features observed in humans with Crouzon ..
- Are the small human-like fossils found on Flores human endemic cretins?Peter J Obendorf
School of Applied Sciences, RMIT University, Melbourne, Vic, Australia
Proc Biol Sci 275:1287-96. 2008..We show that critical environmental factors were potentially present on Flores, how remains of cretins but not of unaffected individuals could be preserved in caves, and that extant oral traditions may provide a record of cretinism...
- Three-dimensional visualization of the craniofacial patient: volume segmentation, data integration and animationR Enciso
Craniofacial Virtual Reality Laboratory, School of Dentistry, University of Southern California, Los Angeles, CA 90089 0641, USA
Orthod Craniofac Res 6:66-71; discussion 179-82. 2003....
- The bone regenerative effect of platelet-rich plasma in combination with an osteoconductive material in rat cranial defectsAdelina S Plachokova
Department of Periodontology and Biomaterials, Radboud University Nijmegen, Medical Centere Nijmegen, Nijmegen, The Netherlands
Clin Oral Implants Res 17:305-11. 2006..Also, no negative effect was seen, and neither PRP nor HA/beta-TCP hampered bone ingrowth into the defects...
- A morphological study of the relationship between arch dimensions and craniofacial structures in adolescents with Class II Division 1 malocclusions and various facial typesToru Kageyama
Division of Hard Tissue Research, Graduate School, Matsumoto Dental University, Nagano, Japan
Am J Orthod Dentofacial Orthop 129:368-75. 2006..The objective of this study was to evaluate dental arch forms associated with various facial types in adolescents with Class II Division 1 malocclusions by using mathematical functions to describe the arch form at clinical bracket points...
- Flores hominid: new species or microcephalic dwarf?Robert D Martin
Academic Affairs, Field Museum, Chicago, Illinois 60605, USA
Anat Rec A Discov Mol Cell Evol Biol 288:1123-45. 2006..The primary evidence, dated at approximately 18,000 y, is a skull and partial skeleton of a very small but dentally adult individual (LB1)...
- A fourth hominin skull from Dmanisi, GeorgiaDavid Lordkipanidze
Georgian National Museum, Tbilisi, Georgia
Anat Rec A Discov Mol Cell Evol Biol 288:1146-57. 2006..1.77 million years ago. Here we describe a fourth skull that is nearly complete, lacking all but one of its teeth at the time of death...
- Craniofacial levels and the morphological maturation of the human skullMarkus Bastir
Hull York Medical School, The University of York, Heslington, York, UK
J Anat 209:637-54. 2006It is well known that the human skull achieves adult size through a superior-inferior gradient of maturation...
- Reproducibility of maxillofacial anatomic landmarks on 3-dimensional computed tomographic images determined with the 95% confidence ellipse methodAtsushi Muramatsu
Department of Orthodontics, Aichi Gakuin University School of Dentistry, Nagoya, Japan
Angle Orthod 78:396-402. 2008..To assess the plotting reproducibility of landmarks on 3-dimensional computed tomography (3D-CT) images through use of the 95% confidence ellipse in order to propose sufficiently stable coordinate systems for 3D-CT measurements...
- Three-dimensional Procrustes analysis of modern human craniofacial formJackie Badawi-Fayad
Museum national d histoire naturelle, Département de Préhistoire USM 204, Institut de Paleontologie Humaine, Paris, France
Anat Rec (Hoboken) 290:268-76. 2007....
- [Procuste cephalometry]X Penin
Orthod Fr 77:407-15. 2006....
- Craniofacial morphology in patients with sickle cell disease: a cephalometric analysisValeria Licciardello
Department of Orthodontics, University of Catania, Italy
Eur J Orthod 29:238-42. 2007....
- Skeletal, dental and soft tissue changes in postural class III malocclusion treated with a maxillary removable applianceElham S J Abu Alhaija
Preventive Dentistry Department, Jordan University of Science and Technology, Irbid, Jordan
J Clin Pediatr Dent 31:149-52. 2006..This longitudinal retrospective cephalometric study was undertaken in an attempt to evaluate the effect of upper removable appliances on the hard and soft tissue structures in subjects with postural Class III...
- A cephalometric study on craniofacial morphology of Iranian children with beta-thalassemia majorF Amini
Department of Orthodontics and Dentofacial Orthopedics, Dental College of Islamic Azad Medical University, Tehran, Iran
Orthod Craniofac Res 10:36-44. 2007..To study cephalometric and facial features of Iranian children with beta-thalassemia major...
- Brain shape in human microcephalics and Homo floresiensisDean Falk
Department of Anthropology, Florida State University, Tallahassee, FL 32306, USA
Proc Natl Acad Sci U S A 104:2513-8. 2007..Despite LB1's having brain shape features that sort it with normal humans rather than microcephalics, other shape features and its small brain size are consistent with its assignment to a separate species...
- Verification of clinical precision after computer-aided reconstruction in craniomaxillofacial surgeryMarc Christian Metzger
Department of Craniomaxillofacial Surgery, Albert Ludwigs University Freiburg, Freiburg, Germany
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:e1-10. 2007..The aim of this study was to evaluate the accuracy of the preoperative planning and the postoperative result regarding the skeletal reconstruction...
- A new method for assessment of craniofacial malformationsSandro Pelo
Maxillofacial Department, , Policlinico A. Gemelli, Rome, Italy
J Craniofac Surg 17:1035-9. 2006..In addition to cephalometric and anthropometric databases, the measurements from 3-D surface reconstructions from CT were used intraoperatively to establish the correct position of skeletal segments...
- Accuracy of three-dimensional (3D) craniofacial cephalometric landmarks on a low-dose 3D computed tomographR Olszewski
Department of Oral and Maxillofacial Surgery, Av Hippocrate 10, Saint Luc University Clinics, Universite Catholique de Louvain, 1200 Brussels, Belgium
Dentomaxillofac Radiol 37:261-7. 2008..The absorbed dose levels for radiosensitive organs in the maxillofacial region during the exposure for both 3D-CT protocols were also measured...
- Parental craniofacial morphology in cleft lip with or without cleft palate as determined by cephalometry: a meta-analysisS M Weinberg
Center for Craniofacial and Dental Genetics, Division of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA
Orthod Craniofac Res 9:18-30. 2006..To integrate findings from previous cephalometric studies comparing the craniofacial complex of unaffected parents with cleft lip with or without cleft palate (CL/P) children to controls with no history of the disease...
- Influence of sex hormone disturbances on the internal structure of the mandible in newborn miceT Fujita
Department of Orthodontics and Craniofacial Developmental Biology, Hiroshima University Graduate School of Biomedical Sciences, Japan
Eur J Orthod 28:190-4. 2006..The findings show that sex hormones are one of the key determinants of mandibular growth and development immediately after birth...
- Neanderthal cranial ontogeny and its implications for late hominid diversityM S Ponce de León
Anthropologisches Institut, Universitat Zurich Irchel, Zurich, Switzerland
Nature 412:534-8. 2001..Evidence for early ontogenetic divergence together with evolutionary stasis of taxon-specific patterns of ontogeny is consistent with separation of Neanderthals and modern humans at the species level...
- Maximal bite force and its associations with spinal posture and craniofacial morphology in young adultsOuti Kovero
Department of Radiology, Institute of Dentistry, University of Helsinki, Helsinki, Finland
Acta Odontol Scand 60:365-9. 2002..No statistically significant correlations existed between MBF and spinal posture, but significant correlations did exist between MBF and craniofacial variables, especially in women...
- Proportion indices in the craniofacial regions of 284 healthy North American white children between 1 and 5 years of ageLeslie G Farkas
Center for Craniofacial Care and Research, The Hospital for Sick Children, and Division of Plastic Surgery, Toronto, Ontario, Canada
J Craniofac Surg 14:13-28. 2003....
- The accuracy of stereolithography in planning craniofacial bone replacementPeter Shih-Hsin Chang
Division of Plastic Surgery, Department of Surgery, Mackey Memorial Hospital, Taipei, Taiwan
J Craniofac Surg 14:164-70. 2003..The mean differences in overall dimensions between the SLMs and skull specimens were 1.5 mm (range: 0-5.5 mm) for craniofacial measures, 1.2 mm (range: 0-4...
- Growth-related shape changes in the fetal craniofacial complex of humans (Homo sapiens) and pigtailed macaques (Macaca nemestrina): a 3D-CT comparative analysisMichael P Zumpano
Department of Anatomy, New York Chiropractic College, Seneca Falls, New York 13148 0800, USA
Am J Phys Anthropol 120:339-51. 2003..5 gestational weeks). For each individual, three-dimensional coordinates of 18 landmarks on the skull were collected from three-dimensional computed tomographic (CT) reconstructed images and two-dimensional CT axial ..
- Craniofacial skeletal deviations following in utero exposure to the anticonvulsant phenytoin: monotherapy and polytherapyH I Orup
The Department of Growth and Development, Harvard School of Dental Medicine, Boston, MA, USA
Orthod Craniofac Res 6:2-19. 2003..To identify and quantify the craniofacial effects from prenatal exposure to phenytoin monotherapy and polytherapy using cephalometric, hand-wrist, and panoramic radiographs and to determine if such deviations persist with age...
- Neandertal faces were not long; modern human faces are shortErik Trinkaus
Department of Anthropology, Campus Box 1114, Washington University, St Louis, MO 63130, USA
Proc Natl Acad Sci U S A 100:8142-5. 2003..Neandertal facial length is not derived. The shortness of recent human facial skeletons is the evolutionarily derived condition...
- Electronic removal of encrustations inside the Steinheim cranium reveals paranasal sinus features and deformations, and provides a revised endocranial volume estimateHermann Prossinger
Institute of Anthroplogy, University of Vienna, Austria
Anat Rec B New Anat 273:132-42. 2003..Third, we assess the extent of the endocranial deformations and, fourth, their implications for our estimation of the braincase volume...
- Vertical and horizontal neoclassical facial canons in Turkish young adultsM G Bozkir
Department of Anatomy, Faculty of Medicine, Cukurova University, 01330 Adana, Turkey
Surg Radiol Anat 26:212-9. 2004..4%/78.9% and 50.0%/52.2% respectively). The mouth width was greater than 1.5 times the nose width in the majority of this study (women/men: 66.9% vs 49.1%)...
- Paleontology. Spanish fossil sheds new light on the oldest great apesElizabeth Culotta
Science 306:1273-4. 2004
- Pierolapithecus catalaunicus, a new Middle Miocene great ape from SpainSalvador Moyà-Solà
Institut de Paleontologia M Crusafont, Escola Industrial 23, Sabadell, Barcelona 08201, Spain
Science 306:1339-44. 2004..The overall pattern suggests that Pierolapithecus is probably close to the last common ancestor of great apes and humans...
- Natural craniofacial changes in the third decade of life: a longitudinal studyAyça Arman Akgül
Department of Orthodontics, Faculty of Dentistry, Baskent University, Ankara, Turkey
Am J Orthod Dentofacial Orthop 122:512-22. 2002..These findings have important clinical implications regarding the long-term stability and retention of orthodontic and orthognathic surgery treatment results...
- Early craniofacial morphology and growth in children with unoperated isolated cleft palateN V Hermann
Department of Pediatric Dentistry, School of Dentistry, University of Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark
Cleft Palate Craniofac J 39:604-22. 2002....
- Dentocraniofacial morphology of 12 Japanese subjects with unilateral cleft lip and palate with a severe Class III malocclusion: a cephalometric study at the pretreatment stage of surgical orthodontic treatmentC Tateishi
Department of Oral and Maxillofacial Surgery, Kobe University School of Medicine, Kobe, Japan
Cleft Palate Craniofac J 38:597-605. 2001..These results show that CLP patients who required surgical orthodontic treatment had a characteristic dentocraniofacial morphology, compared to controls without CLP with Class III malocclusion...
- From genotype to phenotype: the differential expression of FGF, FGFR, and TGFbeta genes characterizes human cranioskeletal development and reflects clinical presentation in FGFR syndromesJ A Britto
Craniofacial Centre, Great Ormond Street Hospital for Children, The Developmental Biology Unit, Institute of Child Health, London, England
Plast Reconstr Surg 108:2026-39; discussion 2040-6. 2001..and FGFR3 are equally expressed throughout the predifferentiated mesenchyme of the cranium, the endochondral skull base, and midfacial mesenchyme...
- Morphology and affinities of new hominin cranial remains from Member 4 of the Sterkfontein Formation, Gauteng Province, South AfricaCharles A Lockwood
Institute of Human Origins and Department of Anthropology, Arizona State University, Tempe, Arizona 85287, USA
J Hum Evol 42:389-450. 2002..africanus. However, two specimens document the possibility that a second, possibly new species is represented among the Member 4 hominins, although such a species is difficult to characterize on cranial evidence alone...
- Pediatric Percutaneous Cochlear Implantation Clinical Validation & ImplementationRobert F Labadie; Fiscal Year: 2010..PCI reduces CI surgery to a single pass of a drill from the lateral skull base to the cochlea...
- Perceptions of Social Risk in Medical Child Abuse EvaluationHeather T Keenan; Fiscal Year: 2010..will both submit and review cases of three injury types (traumatic brain injury, long-bone fracture, and skull fracture) using a web-based template. Physicians will rate their perceptions of social risk for each injury case...
- Combination drug treatment to inhibit multiple cell death pathways after TBIALAN FADEN; Fiscal Year: 2009..associated with a decreased level of consciousness, amnesia, other neurologic or neuropsychological abnormalities, skull fracture, intracranial lesions, or death...
- Development and Validation of a Diagnostic Tool for Infant Head Injuries from FalSUSAN SHEPS contact MARGULIES; Fiscal Year: 2010..Mechanical responses from the model (cortical displacement relative to skull and peak cortical tissue strain) are statistically correlated with the actual occurrence of extra- axial ..
- Development and Validation of a Diagnostic Tool for Infant Head Injuries from FalSusan Margulies; Fiscal Year: 2009..Mechanical responses from the model (cortical displacement relative to skull and peak cortical tissue strain) are statistically correlated with the actual occurrence of extra- axial ..
- Graves' Disease Therapy Risks to Mother and FetusScott A Rivkees; Fiscal Year: 2010..In murine models, we observed that PTU exposure during embryogenesis (E7.5 to 10.5) is associated with skull and cardiac defects, whereas we do not observe malformations in embryos of dams treated with MMI or high doses of ..
- Delivery of Soluble FGFR3 as a Treatment for AchondroplasiaSteven C Ghivizzani; Fiscal Year: 2010..Affected children suffer from abnormal long bone development and deformations of the vertebrae and bones in the skull. There is no cure for achondroplasia, and existing treatments only address some of the complications...
- Genetic Architecture of the Mammalian (Canid) SkeletonKARL LARK; Fiscal Year: 2007..Dogs are genotyped using microsatellite markers and phenotyped from five x-rays comprising the skull, fore- and hind limbs and pelvis...
- Transcranial Sonothrombolysis with Diagnostic UltrasoundThilo Hoelscher; Fiscal Year: 2010..be repeated to optimize US transmit parameters now insonating through intervening wet human cadaveric temporal skull bone. Insonation through bone is limited by sound absorption, scattering and phase aberration...
- Transcranial Sonothrombolysis with Diagnostic UltrasoundThilo Hoelscher; Fiscal Year: 2009..be repeated to optimize US transmit parameters now insonating through intervening wet human cadaveric temporal skull bone. Insonation through bone is limited by sound absorption, scattering and phase aberration...
- COLLAGEN GENE STRUCTURE AND EXPRESSIONBjorn Reino Olsen; Fiscal Year: 2010..that include high myopia, vitreoretinal degeneration, retinal detachment and midline defects in bones of the skull;some patients have imaging abnormalities in the brain suggesting defects in neuronal migration...
- COLLAGEN GENE STRUCTURE AND EXPRESSIONBjorn Olsen; Fiscal Year: 2009..that include high myopia, vitreoretinal degeneration, retinal detachment and midline defects in bones of the skull; some patients have imaging abnormalities in the brain suggesting defects in neuronal migration...
- PHENOGENETICS OF SKULL AND BRAIN INTEGRATION IN CRANIOSYNOSTOSISJOAN THERESE RICHTSMEIER; Fiscal Year: 2010..The skull shape in craniosynostosis can not be explained simply by the premature fusion of sutures, but involves widespread ..
- BONE GROWTH, PERIOSTEAL MIGRATION AND MUSCLE FUNCTIONSusan Herring; Fiscal Year: 1993..to see whether the pattern is produced by the muscle directly, by loading the jaw joint, or by twisting the skull. Aim 4 addresses the problem of how the zygomatic suture affects stress transmission by investigating the physical ..
- Clinical Validation and Testing of Percutaneous Cochlear ImplantationRobert Labadie; Fiscal Year: 2007..demonstrated the concept of percutaneous cochlear access as a single pass of a surgical drill from the lateral skull to the cochlea without injury to adjacent vital structures...
- Clinical Validation and Testing of Percutaneous Cochlear ImplantationRobert F Labadie; Fiscal Year: 2010..demonstrated the concept of percutaneous cochlear access as a single pass of a surgical drill from the lateral skull to the cochlea without injury to adjacent vital structures...
- Cellular and Molecular Mechanisms of Patterned Growth of the Mammalian SkullRobert E Maxson; Fiscal Year: 2010..genetic control of patterned growth during the morphogenesis of a complex, multicomponent structure, the mammalian skull vault...
- BONE GROWTH, PERIOSTEAL MIGRATION, AND MUSCLE FUNCTIONSusan Herring; Fiscal Year: 2001..Major areas of interest for the next project period will be the cranial sutures, the primary loci of skull deformation during function, and the architecture of newly formed periosteal bone, an important determinant of ..
- Permanently Implantable, Intracranial Pressure SensorArye Rosen; Fiscal Year: 2006..Since the intracranial contents exist within a rigid container (skull), direct pressure measurements require neurosurgical procedures, with their attendant risks, discomforts, and ..
- Regional differences in neural crest and mesodermal derived calvarial bone healinMichael T Longaker; Fiscal Year: 2010..The paired parietal frontal bones in the anterior skull are derived from the neural crest and the paired parietal bones, positioned posteriorly, are derived from the ..
- Development of Thermoacoustic Tomography Brain ImagingMark A Anastasio; Fiscal Year: 2010..challenge in TAT brain imaging is to compensate for the distortion introduced into the TAT measurement data by the skull. The broad objective of this proposal is to make TAT brain imaging a practical, useful, and highly effective brain ..
- BONE GROWTH, PERIOSTEAL MIGRATION AND MUSCLE FUNCTIONSusan Herring; Fiscal Year: 2007..The mechanical environment influences skull growth at every level from individual cells to gross structure...
- DYSFUNCTIONAL FGFR SIGNALING IN CRANIOSYNOSTOSISRobert Friesel; Fiscal Year: 2002Craniosynostosis, an abnormality of skull development in which the sutures of the growing calvarial bones fuse prematurely, occurs with a frequency of approximately 1 in 2500 live births...
- MUSCARINIC RECEPTOR COUPLING TO INOSITIDES IN CNSStephen Fisher; Fiscal Year: 2006The regulation of cell volume is of critical importance to the CNS due to the restrictions of the skull. Brain swelling, which may occur in response to a lowering of plasma osmolarity or during cytotoxic edema, is associated with a ..
- EVALUATION OF MEG AS A CURRENT SOURCE IMAGING TECHNIQUEYoshio Okada; Fiscal Year: 1993..The resulting SEF will be measured over the exposed intact scalp (with hairs removed), intact skull and intact dura at a measurement distance of 2 mm from each of these surfaces, using a high-resolution, 4-channel ..
- A Novel Ultrasound Phased Array and Sonication Method for Stroke TreatmentsKullervo Hynynen; Fiscal Year: 2010..It is our hypothesis that transcranial sonication using phased array applicators and patient-specific skull information derived from CT scans can better localize ultrasound energy within the brain, and that this will ..
- PHENOGENETICS OF SKULL AND BRAIN INTEGRATION IN CRANIOSYNOSTOSISJOAN RICHTSMEIER; Fiscal Year: 2009..We are testing developmental associations between skull and brain using 3D data from micro-CT and micro-MR images of the Fgfr2+/S252W and Fgfr2cC342Y/+ mouse models for ..
- EVALUATION OF MEG AS A CURRENT SOURCE IMAGING TECHNIQUEYoshio Okada; Fiscal Year: 2004..e. in the area of human neonatal brain research. Unlike the adults, the skull of the infants has fontanels and sutures which may be abnormally large in pathological cases...
- Brain Drug Delivery Using Parkinson as a Disease ModelVictor Yang; Fiscal Year: 2005The protection by the bone-structured skull, the lack of targeting or retention specificity, and the presence of the impermeable blood brain barrier (BBB) render the brain the least promising territory for drug intervention...
- MOLECULAR GENETICS OF A SYNDROME WITH HEARING IMPAIRMENTJ Post; Fiscal Year: 2004..The delineation of the panoply of genes involved in causing craniosynostosis will enhance our understanding of these diseases and suggest new therapeutic strategies. ..