thoracic duct

Summary

Top Publications

  1. ncbi Effect of cisterna chyli ablation combined with thoracic duct ligation on abdominal lymphatic drainage
    James M Fingeroth
    Vet Surg 34:295; author reply 295. 2005
  2. ncbi [En bloc ligation of the thoracic duct in twelve dogs with idiopathic chylothorax]
    F W Viehoff
    Hoofdafdeling Geneeskunde van Gezelschapsdieren, Faculteit der Diergeneeskunde, Universiteit Utrecht, Postbus 80154, 3508 TD Utrecht
    Tijdschr Diergeneeskd 128:278-83. 2003
  3. ncbi Images in clinical medicine. Chylothorax and chyloperitoneum
    Thai Yen Ly
    University of Toronto, Toronto, ON MN4 3M5, Canada
    N Engl J Med 353:616. 2005
  4. ncbi [Management of postoperative chylothorax]
    B Smati
    Service de Chirurgie Thoracique et Cardiovasculaire, Hôpital Abderrahmen Mami Ariana, Tunisie
    Rev Mal Respir 23:152-6. 2006
  5. ncbi Chylothorax complicating repairs of the descending and thoracoabdominal aorta
    Adnan H Allaham
    Department of Cardiothoracic and Vascular Surgery, The University of Texas Health Science Center at Houston Medical School, 6410 Fannin St, Suite 450, Houston, TX 77030, USA
    Chest 130:1138-42. 2006
  6. doi Prevention of postoperative chylothorax with thoracic duct ligation during video-assisted thoracoscopic esophagectomy for cancer
    Wei Guo
    Department of Thoracic Surgery, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Changjiang Route 10, Daping, Chongqing, 400042, The People s Republic of China
    Surg Endosc 26:1332-6. 2012
  7. doi Nonoperative thoracic duct embolization for traumatic thoracic duct leak: experience in 109 patients
    Maxim Itkin
    Hospital of the University of Pennsylvania, Interventional Radiology, 3400 Spruce St, Philadelphia, PA 19004, USA
    J Thorac Cardiovasc Surg 139:584-89; discussion 589-90. 2010
  8. ncbi Management of chylothorax by percutaneous catheterization and embolization of the thoracic duct: prospective trial
    C Cope
    Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
    J Vasc Interv Radiol 10:1248-54. 1999
  9. ncbi Establishment and characterization of conditionally immortalized endothelial cell lines from the thoracic duct and inferior vena cava of tsA58/EGFP double-transgenic rats
    Mitsuhiro Matsuo
    Department of Anatomy, University of Toyama, Toyama, Japan
    Cell Tissue Res 326:749-58. 2006
  10. ncbi Video-assisted right supradiaphragmatic thoracic duct ligation for non-traumatic recurrent chylothorax
    Michel Christodoulou
    Division of Thoracic Surgery, Centre Hospitalier Universitaire Vaudois, 1010 Lausanne, Switzerland
    Eur J Cardiothorac Surg 29:810-4. 2006

Research Grants

  1. Cholesterol and Lymphatic Transport of Molecules and Cells
    Gwendalyn Randolph; Fiscal Year: 2009
  2. Cholesterol and Lymphatic Transport of Molecules and Cells
    Melody A Swartz; Fiscal Year: 2010
  3. Mechanisms of Lymphatic Pump-Enhancement of Immune Function
    LISA HODGE; Fiscal Year: 2009
  4. Shock, trauma and gut origin of sepsis
    Edwin A Deitch; Fiscal Year: 2010
  5. Shock, trauma and gut origin of sepsis
    Edwin Deitch; Fiscal Year: 2009
  6. Shock, trauma and gut origin of sepsis
    Edwin A Deitch; Fiscal Year: 2010
  7. Shock, trauma and gut origin of sepsis
    Edwin A Deitch; Fiscal Year: 2010
  8. CIRCUIT ANALYSIS OF THE LYMPHATIC SYSTEM
    Robert Drake; Fiscal Year: 1990
  9. MOLECULAR CHARACTERIZATION OF FAMILIAL LYMPHEDEMA
    Mansoor Sarfarazi; Fiscal Year: 2003
  10. MOLECULAR CHARACTERIZATION OF FAMILIAL LYMPHEDEMA
    Mansoor Sarfarazi; Fiscal Year: 2001

Detail Information

Publications197 found, 100 shown here

  1. ncbi Effect of cisterna chyli ablation combined with thoracic duct ligation on abdominal lymphatic drainage
    James M Fingeroth
    Vet Surg 34:295; author reply 295. 2005
  2. ncbi [En bloc ligation of the thoracic duct in twelve dogs with idiopathic chylothorax]
    F W Viehoff
    Hoofdafdeling Geneeskunde van Gezelschapsdieren, Faculteit der Diergeneeskunde, Universiteit Utrecht, Postbus 80154, 3508 TD Utrecht
    Tijdschr Diergeneeskd 128:278-83. 2003
    Twelve dogs with idiopathic chylothorax were treated by en bloc ligation of the thoracic duct. Six dogs recovered completely. Minimal follow-up in this group was 12 months...
  3. ncbi Images in clinical medicine. Chylothorax and chyloperitoneum
    Thai Yen Ly
    University of Toronto, Toronto, ON MN4 3M5, Canada
    N Engl J Med 353:616. 2005
  4. ncbi [Management of postoperative chylothorax]
    B Smati
    Service de Chirurgie Thoracique et Cardiovasculaire, Hôpital Abderrahmen Mami Ariana, Tunisie
    Rev Mal Respir 23:152-6. 2006
    ..A chylothorax can occur following any intrathoracic procedure. It is generally straightforward to make the diagnosis but optimal management can be problematic...
  5. ncbi Chylothorax complicating repairs of the descending and thoracoabdominal aorta
    Adnan H Allaham
    Department of Cardiothoracic and Vascular Surgery, The University of Texas Health Science Center at Houston Medical School, 6410 Fannin St, Suite 450, Houston, TX 77030, USA
    Chest 130:1138-42. 2006
    ..Chylothorax occurring during thoracic aortic surgery is an infrequent but serious complication. The purpose of this study was to analyze our experience with this complication and the resulting outcomes...
  6. doi Prevention of postoperative chylothorax with thoracic duct ligation during video-assisted thoracoscopic esophagectomy for cancer
    Wei Guo
    Department of Thoracic Surgery, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Changjiang Route 10, Daping, Chongqing, 400042, The People s Republic of China
    Surg Endosc 26:1332-6. 2012
    ..In this retrospective series, we evaluated the results of preventive intraoperative thoracic duct ligation in patients who underwent video-assisted thoracoscopic esophagectomy for cancer.
  7. doi Nonoperative thoracic duct embolization for traumatic thoracic duct leak: experience in 109 patients
    Maxim Itkin
    Hospital of the University of Pennsylvania, Interventional Radiology, 3400 Spruce St, Philadelphia, PA 19004, USA
    J Thorac Cardiovasc Surg 139:584-89; discussion 589-90. 2010
    ..To demonstrate the efficacy of a minimally invasive, nonoperative, catheter-based approach to the treatment of traumatic chyle leak...
  8. ncbi Management of chylothorax by percutaneous catheterization and embolization of the thoracic duct: prospective trial
    C Cope
    Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
    J Vasc Interv Radiol 10:1248-54. 1999
    To prospectively assess the efficacy of percutaneous transabdominal thoracic duct catheterization and embolization in the management of patients with high-output chylothoracic effusions.
  9. ncbi Establishment and characterization of conditionally immortalized endothelial cell lines from the thoracic duct and inferior vena cava of tsA58/EGFP double-transgenic rats
    Mitsuhiro Matsuo
    Department of Anatomy, University of Toyama, Toyama, Japan
    Cell Tissue Res 326:749-58. 2006
    ..The cloned cell lines were named TR-LE (temperature-sensitive rat lymphatic endothelial cells from thoracic duct) and TR-BE (temperature-sensitive rat blood-vessel endothelial cells from inferior vena cava), respectively, ..
  10. ncbi Video-assisted right supradiaphragmatic thoracic duct ligation for non-traumatic recurrent chylothorax
    Michel Christodoulou
    Division of Thoracic Surgery, Centre Hospitalier Universitaire Vaudois, 1010 Lausanne, Switzerland
    Eur J Cardiothorac Surg 29:810-4. 2006
    ..We report our experience with video-assisted right-sided supradiaphragmatic thoracic duct ligation for non-traumatic, non-postoperative persistent or recurrent chylothorax.
  11. ncbi Thoracic duct ligation and pericardectomy for treatment of idiopathic chylothorax
    Theresa W Fossum
    Michael E DeBakey Institute for Comparative Cardiovascular Sciences and Biomedical Devices, College of Veterinary Medicine, Texas A and M University, College Station, TX, USA
    J Vet Intern Med 18:307-10. 2004
    ..abnormal venous pressures would act to impede the drainage of chyle via lymphaticovenous communications after thoracic duct (TD) ligation...
  12. doi Thoracic duct embolization: a new treatment for massive leak after neck dissection
    Neel Patel
    Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Laryngoscope 118:680-3. 2008
    Chylothorax results from injury to the thoracic duct or one of its branches. It is an uncommon but possibly serious complication of thoracic or head and neck surgery...
  13. doi Ultrasound-guided mesenteric lymph node iohexol injection for thoracic duct computed tomographic lymphography in cats
    Mieun Kim
    Department of Veterinary Medical Imaging, College of Veterinary Medicine, Seoul National University, Seoul 151 742, Korea
    Vet Radiol Ultrasound 52:302-5. 2011
    ..The thoracic duct and its branches were clearly delineated in CT images of seven cats studied...
  14. ncbi Chylothorax treated via thoracic duct ligation and omentalization
    Kayla Stewart
    Department of Surgery, Chesapeake Veterinary Surgical Specialists, 808 Bestgate Road, Annapolis, Maryland 21401, USA
    J Am Anim Hosp Assoc 46:312-7. 2010
    ..All animals received thoracic duct ligation and thoracic omentalization...
  15. ncbi Thoracic duct ligation for persistent chylothorax after pediatric cardiothoracic surgery
    Dilip S Nath
    Division of Cardiothoracic Surgery, Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California 90027, USA
    Ann Thorac Surg 88:246-51; discussion 251-2. 2009
    There is considerable literature on incidence and medical management of postsurgical chylothorax in children but little is known about outcomes of thoracic duct ligation (TDL) for patients refractory to medical therapy.
  16. ncbi Introduction of lymphangiography and percutaneous embolization of the thoracic duct in a stepwise approach to the management of chylous fistulas
    Arnoud T van Goor
    Department of Head and Neck Oncology, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    Head Neck 29:1017-23. 2007
    ..This article reports on percutaneous embolization of the thoracic duct through catheterization of the retroperitoneal lymph vessels.
  17. doi Large mediastinal thoracic duct cyst
    Michele De Santis
    Department of Pulmonology, Hospital Center, Coimbra, Portugal
    Interact Cardiovasc Thorac Surg 10:138-9. 2010
    b>Thoracic duct cysts of the mediastinum are extremely rare. The etiology is related to a congenital or degenerative weakness in the wall of the thoracic duct. Symptoms may arise from compression of adjacent structures...
  18. ncbi Transabdominal ligation of the thoracic duct as treatment of choice for postoperative chylothorax after esophagectomy
    G Schumacher
    Department of General, Visceral, and Transplantation Surgery, Humboldt University, Charite Campus Virchow Klinikum, Berlin, Germany
    Dis Esophagus 20:19-23. 2007
    Postoperative chylothorax after injury of the thoracic duct during esophagectomy is a rare but severe complication which may lead to serious problems such as loss of fat and proteins, and immunodeficiency...
  19. ncbi Human thoracic duct in vitro: diameter-tension properties, spontaneous and evoked contractile activity
    Niklas Telinius
    Dept of Physiology and Biophysics, Aarhus Univ, Ole Worms Alle 4, Universitetsparken, DK 8000 Arhus C, Denmark
    Am J Physiol Heart Circ Physiol 299:H811-8. 2010
    The current study characterizes the mechanical properties of the human thoracic duct and demonstrates a role for adrenoceptors, thromboxane, and endothelin receptors in human lymph vessel function...
  20. ncbi Cisterna chyli ablation with thoracic duct ligation for chylothorax: results in eight dogs
    Kei Hayashi
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
    Vet Surg 34:519-23. 2005
    To report use of combined cisterna chyli ablation (CCA) and thoracic duct ligation (TDL) for treatment of spontaneously occurring chylothorax in dogs.
  21. ncbi Percutaneous treatment of high-output chylothorax with embolization or needle disruption technique
    Christoph A Binkert
    Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, Massachusetts 02115, USA
    J Vasc Interv Radiol 16:1257-62. 2005
    Surgical ligation of the thoracic duct is associated with a high degree of morbidity; therefore, a minimally invasive approach is desirable. Herein, eight percutaneously treated patients are described...
  22. ncbi Treatment of idiopathic chylothorax in 14 dogs by ligation of the thoracic duct and partial pericardiectomy
    B Carobbi
    Dick White Referrals, London Road, Six Mile Bottom, Newmarket, Suffolk CB8 0UH, UK
    Vet Rec 163:743-5. 2008
    The outcome and complications associated with thoracic duct ligation combined with partial pericardiectomy in 14 dogs with idiopathic chylothorax were investigated retrospectively...
  23. ncbi Percutaneous translymphatic thoracic duct embolization for treatment of chylothorax
    H Schild
    Klinik fUr Allgemein, Viszeral, Thorax und Gefässchirurgie Rheinische Friedrich Wilhelms Universität Bonn
    Rofo 173:580-2. 2001
    A modified technique for transabdominal, translymphatic occlusion of the thoracic duct is described...
  24. doi Retrograde cannulation of the thoracic duct and embolization of the cisterna chyli in the treatment of chylous ascites
    Derek Mittleider
    Department of Radiology, Section of Vascular and Interventional Radiology, Maine Medical Center, 22 Bramhall St, Portland, ME 04102, USA
    J Vasc Interv Radiol 19:285-90. 2008
    ..After the failure of conventional percutaneous direct cisterna chyli cannulation, the authors accessed the thoracic duct directly from the subclavian vein...
  25. doi Thoracoscopic thoracic duct ligation and thoracoscopic pericardectomy for treatment of chylothorax in dogs
    David A Allman
    Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, USA
    Vet Surg 39:21-7. 2010
    To report the use of thoracoscopic thoracic duct ligation (TDL) and pericardectomy for treatment of chylothorax.
  26. pmc Inhibition of the active lymph pump by flow in rat mesenteric lymphatics and thoracic duct
    Anatoliy A Gashev
    Department of Medical Physiology, Cardiovascular Research Institute, College of Medicine, Texas A and M University System Health Science Center, 336 Reynolds Medical Building, College Station, TX 77843 1114, USA
    J Physiol 540:1023-37. 2002
    ..Imposed flow inhibited the active lymph pump in both mesenteric lymphatics and in the thoracic duct. The active pump of the thoracic duct appeared more sensitive to flow than did the active pump of the ..
  27. ncbi Thoracic duct cysts: a rare differential diagnosis
    Frank Gottwald
    Department of Otolaryngology Head and Neck Surgery, University Erlangen Nuremberg, Erlangen, Germany
    Otolaryngol Head Neck Surg 132:330-3. 2005
    Cysts of the thoracic duct located in the supraclavicular region are uncommon. To date only 12 cases in this topographic area have been described in the literature...
  28. doi Peritoneoatrial shunting for intractable chylous ascites complicating thoracic duct ligation
    Francoise Le Pimpec-Barthes
    Department of Thoracic Surgery, Georges Pompidou European Hospital, Paris Descartes University, Paris, France
    Ann Thorac Surg 87:1601-3. 2009
    b>Thoracic duct ligation for chylothorax is considered a safe and efficient procedure. However, we observed two cases that were complicated by intractable chylous ascites...
  29. doi Complete remission of a lymphoma-associated chylothorax by radiotherapy of the celiac trunk and thoracic duct
    Johanna Gerstein
    Department of Radiation Oncology, Hannover Medical School, Hannover, Germany
    Strahlenther Onkol 184:484-7. 2008
    ..A chylothorax is a rare complication of mostly advanced malignant lymphomas. A case of a refractory chylothorax unresponsive to chemotherapy and successfully treated with radiotherapy is reported...
  30. ncbi Anatomic landmarks for the cervical portion of the thoracic duct
    Kevin Ammar
    Pediatric Neurosurgery, Children s Hospital, Birmingham, Alabama 35233, USA
    Neurosurgery 53:1385-7; discussion 1387-8. 2003
    Avoidance of injury to the thoracic duct during neurosurgical procedures involving the cervical region depends on a working knowledge of its location...
  31. ncbi Thoracoscopic management of thoracic duct injury: Is there a place for conservatism?
    S Kumar
    Departments of Surgical Disciplines, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
    J Postgrad Med 50:57-9. 2004
    b>Thoracic duct injury is a rare but serious complication following chest surgeries and major neck dissections. Clinically, it can present as cervical chylous fistula, chylothorax or chylopericardium...
  32. doi Ultrasonic scalpel for sealing of the thoracic duct: evaluation of effectiveness in an animal model
    Haruhiko Nakayama
    Division of Thoracic Surgery, Kanagawa Cancer Center, Yokohama 241 0815, Japan
    Interact Cardiovasc Thorac Surg 9:399-401. 2009
    ..The whole length of thoracic duct of each pig was clearly imaged by pigment...
  33. ncbi Somatostatin analog treatment of a cervical thoracic duct fistula
    Carl N Valentine
    Department of General Surgery, 785 Jelke Building, Rush Presbyterian St Luke s Medical Center, 1653 W Congress Parkway, Chicago, IL 60612, USA
    Head Neck 24:810-3. 2002
    Reoperation for recurrent thyroid cancer poses an increased risk of complications, including thoracic duct fistula. Treatment of this complication is controversial...
  34. ncbi Ligation of the thoracic duct for the treatment of chylothorax in heart diseases
    Paulo M Pêgo-Fernandes
    Instituto do Coracao, Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo, Brazil
    Arq Bras Cardiol 81:309-17. 2003
    ..We report 4 cases of chylothorax in patients who were successfully treated with this approach, which resulted in a decrease in pleural drainage without recurrent chylothorax...
  35. ncbi Temporal changes in the distribution of thoracic duct lymphoblasts to synovium and other tissues of rats with adjuvant-induced arthritis
    Leslie G Cleland
    The Arthritis Research Laboratory of the Hanson Centre for Cancer Research, Institute of Medical and Veterinary Science, University of Adelaide, Adelaide, South Australia, Australia
    Immunol Cell Biol 80:148-55. 2002
    ..b>Thoracic duct lymphoblasts labelled in vitro with [125I]-iododeoxyuridine were detected in recipient rats by external ..
  36. ncbi Minimally invasive management of chylous fistula after esophagectomy
    J D Hayden
    The Department of Esophago Gastric Surgery, The General Infirmary at Leeds, Great George Street, Leeds LS1 3EX, UK
    Dis Esophagus 20:251-5. 2007
    ..Open surgery may be appropriate where minimally invasive approaches fail or where the availability of such skills is limited...
  37. ncbi Increased lymphatic flow in the thoracic duct during manipulative intervention
    E Marty Knott
    University of North Texas Health Science Center at Fort Worth Texas College of Osteopathic Medicine, Department of Integrative Physiology, Fort Worth, TX 76107 2644, USA
    J Am Osteopath Assoc 105:447-56. 2005
    ..The authors surgically instrumented five mongrel dogs to record lymphatic flow in the thoracic duct (TDF) and cardiac variables during three intervention protocols...
  38. ncbi Abdominal lymphatic pump treatment increases leukocyte count and flux in thoracic duct lymph
    Lisa M Hodge
    Department of Molecular Biology and Immunology, Osteopathic Research Center, The University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Lymphat Res Biol 5:127-33. 2007
    ..In this study, the thoracic duct of eight anesthetized mongrel dogs was catheterized, so the immediate effects of LPT on lymph flow and ..
  39. ncbi Treatment of chylothorax by robotic thoracic duct ligation
    Kari J Thompson
    City of Hope, Duarte, California 91010, USA
    Ann Thorac Surg 85:334-6. 2008
    ..After left lower lobectomy, left-sided chylothorax developed. Conservative management failed, and a robotic right-sided thoracic duct ligation was performed. Other treatment options are reviewed.
  40. pmc Thoracoscopic ligation of the thoracic duct
    G Stringel
    Department of Surgery, New York Medical College, Westchester Medical Center, Valhalla, New York 10595, USA
    JSLS 4:239-42. 2000
    When nonoperative treatment of chylothorax fails, thoracic duct ligation is usually performed through a thoracotomy...
  41. ncbi Thoracoscopic thoracic duct ligation for traumatic chylothorax
    K G Buchan
    Department of Cardiothoracic Surgery, Papworth Hospital, Papworth Everard, Cambridge, United Kingdom
    Ann Thorac Surg 72:1366-7. 2001
    ..This usually entails thoracotomy or laparotomy. We report a case in which successful ligation of a torn thoracic duct was achieved using a video-assisted thoracoscopic technique.
  42. ncbi Management of chyle fistula utilizing thoracoscopic ligation of the thoracic duct
    Chad B Gunnlaugsson
    Department of Otolaryngology, University of Michigan, Ann Arbor, MI 48109 0312, USA
    ORL J Otorhinolaryngol Relat Spec 66:148-54. 2004
    To document the treatment of refractory chyle leaks using thoracoscopic thoracic duct ligation and provide systematic guidelines to manage chyle leaks.
  43. pmc Characterization of thoracic duct cells that transfer polyarthritis
    L D Spargo
    The Arthritis Research Laboratory of the Hanson Centre for Cancer Research, Institute of Medical and Veterinary Science, Adelaide, SA, Australia
    Clin Exp Immunol 126:560-9. 2001
    ..distribution of arthritogenic effector lymphocytes that emerge in the efferent lymph and pass through the thoracic duct (TD) to the circulation...
  44. pmc Thoracic duct drainage in rheumatoid arthritis
    J H Vaughan
    Clin Exp Immunol 58:645-53. 1984
    b>Thoracic duct drainage (TDD) led to major improvement of disease in two of five patients with severe rheumatoid arthritis and lesser improvement in two others...
  45. ncbi Thoracoscopic thoracic duct ligation for chylothorax after traumatic subclavian artery injury
    Newton Roech Aerts
    Department of Vascular Surgery, Complexo Hospitalar Santa Casa de Porto Alegre Fundação Faculdade Federal de Ciências Médicas de Porto Alegre, Porto Alegre, Brazil
    J Thorac Cardiovasc Surg 131:752-3. 2006
  46. ncbi Management of unremitting chylothorax by percutaneous embolization and blockage of retroperitoneal lymphatic vessels in 42 patients
    Constantin Cope
    Section of Interventional Radiology and Thoracic Surgery, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Pennsylvania 19104, USA
    J Vasc Interv Radiol 13:1139-48. 2002
    ..To demonstrate the applicability, technique, and efficacy of percutaneous transabdominal catheter embolization or needle disruption of retroperitoneal lymphatic vessels in the treatment of high-output or unremitting chylothorax...
  47. ncbi [Tuberculous chylothorax: case report and review of the literature]
    M Saumoy
    Servicio de Medicina Interna, Hospital Universitari Joan XXIII, Universitat Rovira i Virgili, Tarragona, Spain
    An Med Interna 22:238-40. 2005
    ....
  48. ncbi A novel technique of management of high output chyle leak after neck dissection
    Sajid S Qureshi
    Department of Surgical Oncology, Tata Memorial Hospital, Ernest Borges Road, Parel, Bombay, India
    J Surg Oncol 96:176-7. 2007
    ..Occasionally on surgical exploration the chyle leak is diffuse and ligation of the bed of thoracic duct is not adroit to stopping the chyle leak...
  49. ncbi Thoracic duct injury during esophagectomy: 20 years experience at a tertiary care center in a developing country
    D V L N Rao
    Department of GI Surgery and Liver Transplantation, All India Institute of Medical Sciences, New Delhi 110029, India
    Dis Esophagus 17:141-5. 2004
    b>Thoracic duct injury is an uncommon complication of esophagectomy. Experience in managing these cases is limited to large centers performing esophagectomies in good numbers...
  50. ncbi [Case of bilateral chylothorax with systemic lupus erythematosus complicated by steroid-/immunosuppressant-resistant pleural effusion]
    Yusuke Narita
    Department of Respiratory Medicine, Yokohama Municipal Citizens Hospital
    Nihon Kokyuki Gakkai Zasshi 46:120-5. 2008
    ..She underwent thoracoscopy-aided ligation of the thoracic duct. After the operation, bilateral pleurodesis was performed by intrathoracic injection of OK-432, because of ..
  51. ncbi The effect of cisterna chyli ablation combined with thoracic duct ligation on abdominal lymphatic drainage
    Gretchen K Sicard
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
    Vet Surg 34:64-70. 2005
    To evaluate the effect of cisterna chyli ablation (CCA) and thoracic duct ligation (TDL) on abdominal lymphatic drainage in normal dogs.
  52. ncbi Diaphragmatic fenestration for resistant chylothorax
    Sachin Talwar
    Ann Thorac Surg 82:767-8. 2006
  53. ncbi Post-traumatic cervical chyloma
    Juan Gomez
    Department of Radiology, Tulane University Medical Center, New Orleans, USA
    Ear Nose Throat J 87:12, 14. 2008
  54. pmc Thoracic duct variations may complicate the anterior spine procedures
    Omer Akcali
    Orthopaedics and Traumatology, Dokuz Eylul University, Izmir, Turkey
    Eur Spine J 15:1347-51. 2006
    The aim of this study is to localize and document the anatomic features of the thoracic duct and its tributaries with special emphasis on the spinal surgery point of view...
  55. doi Chylothorax revisited
    Sameh Ibrahim Sersar
    Eur J Cardiothorac Surg 33:1159, author reply 1159-60. 2008
  56. ncbi VATS thoracic-duct division for aortic surgery-related chylous leakage
    Toshiya Ohtsuka
    Department of Cardiovascular Surgery, Tokyo Metropolitan Fuchu General Hospital, 2 9 2 Musashidai, Fuchu shi, Tokyo 183 0042, Japan
    Eur J Cardiothorac Surg 27:153-5. 2005
    ..Individual exposure and division of the thoracic duct was accomplished using an ultrasonic coagulator. The operating time was 22+/-5...
  57. ncbi Combined late diagnosed right main bronchial disruption and chylothorax from blunt chest trauma
    Cemal Ozcelik
    Department of Thoracic Surgery, Dicle University School of Medicine, Diyarbakir, Turkey
    Ann Thorac Surg 78:e61-2. 2004
    ..We report the case of a patient who presented late after traumatic rupture of the right main bronchus who also had a traumatic chylothorax...
  58. ncbi Thoracoscopic thoracic duct sealing with LigaSure in two children with refractory postoperative chylothorax
    Karim Khelif
    Department of Pediatric Surgery, Queen Fabiola Children s University Hospital, Brussels, Belgium
    J Laparoendosc Adv Surg Tech A 17:137-9. 2007
    Chylothorax is an uncommon complication of cardiac surgery. We report two cases of the thoracoscopic management of persistent postoperative chylothorax by thoracic duct thermofusion and section with the LigaSure device.
  59. ncbi Supradiaphragmatic thoracic duct clipping for chylothorax through left-sided video-assisted thoracoscopic surgery
    Atsushi Watanabe
    Department of Thoracic and Cardiovascular Surgery, Sapporo Medical University School of Medicine, South 1, West 16, Chuo Ku, Sapporo 060 8543, Japan
    Eur J Cardiothorac Surg 31:313-4. 2007
    ..Traditional surgical management for cases refractory to conservative treatment is thoracic duct ligation through a right open thoracotomy or closure of the site of duct laceration through an open ..
  60. ncbi Chylothorax
    Ioannis E Platis
    General Surgery Program, State University of New York at Buffalo, 193 Summer Street, Buffalo, NY 14222, USA
    Thorac Surg Clin 16:209-14. 2006
    ..Clipping of the thoracic duct or chemical pleurodesis may be performed with minimal morbidity and mortality...
  61. ncbi Surgical management of a double-chambered right ventricle and chylothorax in a Labrador retriever
    R Tanaka
    Department of Veterinary Surgery, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu shi, Japan
    J Small Anim Pract 47:405-8. 2006
    ..A combination of thoracic duct ligation and passive pleuroperitoneal shunting was effective in the resolution of the chyle effusion.
  62. ncbi Lymphography of the thoracic duct by percutaneous injection of iohexol into the popliteal lymph node of dogs: experimental study and clinical application
    Kiyokazu Naganobu
    Veterinary Teaching Hospital, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan
    Vet Surg 35:377-81. 2006
    To evaluate the efficacy of percutaneous administration of iohexol into the popliteal lymph node as a non-invasive technique for thoracic duct lymphangiography in dogs.
  63. ncbi Chylothorax and chylopericardium as the initial clinical manifestation of Behcet's disease
    H Moon
    Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School, Institute of Clinical Medicine, 634 18, Geum Am Dong, Duck Jin Gu, Jeonju, Chonbuk, 561 712, South Korea
    Rheumatol Int 28:375-7. 2008
    ..He was treated due to chylothorax and chylopericardium with SVC syndrome before diagnosis of BD. SVC thrombosis complicated by chylothorax and chyolpericardium can be a rare presenting initial symptom of BD...
  64. ncbi Chylothorax and chyloperitoneum
    Marlys H Witte
    N Engl J Med 354:879; author reply 879. 2006
  65. ncbi Gorham disease: an intraoperative case study
    James Underwood
    Phoebe Putney Memorial Hospital, Albany, GA, USA
    AANA J 74:45-8. 2006
    ..involves a 47-year-old man with Gorham disease complicated by unilateral chylothorax who was treated with thoracic duct ligation...
  66. ncbi Chylothorax following cardiac surgery caused by unusual lymphatic anatomy
    Pradeep Narayan
    Bristol Heart Institute, Bristol Royal Infirmary, Bristol BS2 8HW, United Kingdom
    Asian Cardiovasc Thorac Ann 15:e58-9. 2007
    Chylothorax due to injury to the thoracic duct and lymphatic channels during left internal thoracic artery harvest is well described...
  67. ncbi [Thoracoscopic clipping of the thooracic duct for chylothorax following esophagectomy: report of a case]
    Mitsuhiro Kamiyoshihara
    Department of General Thoracic Surgery, Maebashi Red Cross Hospital, Maebashi, Japan
    Kyobu Geka 58:1189-91. 2005
    Thoracoscopic clipping of the thoracic duct was successfully performed for the treatment of postoperative chylothorax. Chylothorax occurred in a 67-year-old man following an esophagectomy for esophageal cancer...
  68. ncbi [Case of idiopathic chylothorax successfully treated with surgical ligation of thoracic ducts]
    Yoshiko Inomoto
    Second Department of Internal Medicine, Nagasaki University School of Medicine
    Nihon Kokyuki Gakkai Zasshi 45:804-7. 2007
    ..The leakage of lymph fluid from the right posterior mediastinum was identified by lymphatic scintigraphy and she was successfully treated with surgical ligation of the thoracic ducts...
  69. ncbi Thoracoscopic direct suture repair of thoracic duct injury after thoracoscopic mediastinal surgery
    Deog Gon Cho
    Department of Thoracic and Cardiovascular Surgery, St Vincent s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Gyeonggi Do 442 723, South Korea
    Surg Laparosc Endosc Percutan Tech 17:60-1. 2007
    Iatrogenic chylothorax is an uncommon thoracic duct injury, but well-known and serious complication after thoracic surgeries...
  70. ncbi Management of chylothorax via percutaneous embolization
    Constantin Cope
    Radiology Department Hospital, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Curr Opin Pulm Med 10:311-4. 2004
    ..is to present a novel radiologic percutaneous transabdominal technique for treating high-output chylothorax by thoracic duct embolization, and to demonstrate that it can be potentially safer than the traditional treatment by surgical ..
  71. ncbi [The optimal procedure for chylothorax after operation for thoracic esophageal cancer; reasonable approaches to the thoracic duct from the point of view of routes for esophageal replacement]
    H Terashima
    Department of Surgery, Hiraka General Hospital, Yokote, Japan
    Kyobu Geka 56:465-8. 2003
    ..and discuss ideal approaches that are less invasive and make it possible to provide better exposure of the thoracic duct. In selecting the ideal approach, the most important thing is differences in routes for esophageal replacement...
  72. ncbi Thoracoscopic management of cervical thoracic duct injuries: an alternative approach
    Kirby J Scott
    Department of Otolaryngology, Naval Medical Center Portsmouth, VA 23708, USA
    Otolaryngol Head Neck Surg 128:755-7. 2003
  73. ncbi Treatment of postoperative chylothorax through laparoscopic thoracic duct ligation
    B C Vassallo
    Department of Thoracic Surgery and Chief of Lung Transplantation, Italian Hospital, Gascon 450, Buenos Aires, Argentina
    Eur J Cardiothorac Surg 21:556-7. 2002
    We report the laparoscopic transhiatal thoracic duct ligation to solve postoperative chylothorax after right total pleurectomy for malignant diffuse mesothelioma.
  74. ncbi Thoracoscopic ultrasonic coagulation of thoracic duct in management of postoperative chylothorax
    Sadanori Takeo
    Department of Thoracic Surgery, National Kyushu Medical Center, Fukuoka, Japan
    Ann Thorac Surg 74:263-5. 2002
    ..Thoracoscopic high-frequency ultrasonic coagulation of the thoracic duct without clipping finally stopped chyle production...
  75. ncbi Chylothorax in chronic lymphocytic leukemia patient
    Clinton H Doerr
    Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Hematol 70:237-40. 2002
    ..to experience re-accumulation of fluid, and therefore, video-assisted thoracotomy with mass ligation of the thoracic duct region plus pleurodesis was performed to resolve the chylothorax...
  76. ncbi Laparoscopic ligation of the thoracic duct in management of chylothorax
    Orlando J Icaza
    Southern Illinois University School of Medicine, Division of General Surgery, Springfield, USA
    J Laparoendosc Adv Surg Tech A 12:129-33. 2002
    ..We feel that this technique offers surgeons a valid, minimally invasive treatment option for a persistent chylothorax in which conservative management or more direct thoracic procedures have failed to control the chyle leak...
  77. ncbi Current management of postoperative chylothorax
    H Fahimi
    Department of Cardiothoracic Surgery, St Antonius Hospital, Nieuwegein, The Netherlands
    Ann Thorac Surg 71:448-50; discussion 450-1. 2001
    ..In addition, 7 patients needed surgical intervention, including one thoracotomy and six VATS. The site of thoracic duct laceration was identified and treated with VATS in 4 patients...
  78. ncbi [Congenital and acquired chylothorax]
    N Tommasoni
    Cattedra di Chirurgia Pediatrica, Azienda Ospedaliera Universita di Padova
    Pediatr Med Chir 24:21-8. 2002
    ..The authors also review the literature and their experience of congenital and postoperative chylothorax in order to establish guidelines for the diagnosis and management of both primary and postoperative chylothorax in paediatric age...
  79. ncbi [Surgery technique: preventive ligation of the thoracic duct during esophagectomy for cancer]
    A Sauvanet
    Service de Chirurgie Digestive, Hopital Beaujon, 100, boulevard du General Leclerc, 92110 Clichy, France
    Ann Chir 127:228-31. 2002
    Chylothorax is a rare but life-threatening complication of esophagectomy for cancer. Elective ligation of the thoracic duct above the diaphragm does not suppress completely the risk of chylothorax due to possible trauma of the thoracic ..
  80. ncbi Chylous effusions complicating lymphoma: a serious event with octreotide as a treatment option
    J Evans
    Department of Haematology and Respiratory Medicine, St Helier Hospital, Carshalton, Surrey, UK
    Hematol Oncol 21:77-81. 2003
    Chylous effusions have an identical appearance to milk and occur when the thoracic duct is blocked...
  81. ncbi Advantage of earlier thoracoscopic clipping of thoracic duct for post-operation chylothorax following thoracic aneurysm surgery
    Nobuaki Hirata
    Division of Cardiovascular Surgery, Takarazuka Municipal Hospital, Hyogo, Japan
    Jpn J Thorac Cardiovasc Surg 51:378-80. 2003
    We report that an earlier thoracoscopic clipping of the thoracic duct was advantageous in a case of post-operation chylothorax that occurred following thoracic aneurysm surgery...
  82. ncbi Chylothorax after radiotherapy in oesophageal carcinoma
    A H Thomson
    Gloucestershire Oncology Centre, Cheltenham General Hospital, Cheltenham, UK
    Lancet Oncol 4:703-4. 2003
  83. ncbi The "innocent bystander" complications following esophagectomy: atrial fibrillation, recurrent laryngeal nerve injury, chylothorax, and pulmonary complications
    Seth Force
    The Emory Clinic, Emory School of Medicine, 1365 Clifton Road NE, 2nd Floor, Suite 2100, Atlanta, GA 30322, USA
    Semin Thorac Cardiovasc Surg 16:117-23. 2004
  84. ncbi [Surgery for chylothorax]
    M Riquet
    Service de Chirurgie Thoracique, Hopital Europeen Georges Pompidou, 20 40, rue Leblanc, 75015 Paris
    Rev Pneumol Clin 60:104-8. 2004
    ..Chylothorax is produced by leaks from the thoracic duct or from one of its collaterals subsequent to valve incompetence...
  85. ncbi Bilateral chylothorax after neck dissection
    Jose M Busquets
    Department of Otolaryngology Head and Neck Surgery, University of Puerto Rico School of Medicine, San Juan, Puerto Rico
    Otolaryngol Head Neck Surg 130:492-5. 2004
  86. ncbi Reduced lymphatic drainage of dialysate from the peritoneal cavity during acute peritonitis in sheep
    H Rodela
    Trauma Research Program, Sunnybrook Health Science Centre, Toronto, Ontario, Canada
    Perit Dial Int 16:163-71. 1996
    ..fifth groups (controls and casein-injected) lymph was collected from the caudal mediastinal lymph node and the thoracic duct, both of which are involved in the lymphatic drainage of the peritoneal cavity (peritonitis induced with ..
  87. ncbi Physiologic aspects of lymphatic contractile function: current perspectives
    Anatoliy A Gashev
    Department of Medical Physiology, Cardiovascular Research Institute, College of Medicine, Texas A and M University System Health Science Center, College Station, Texas 77843 1114, USA
    Ann N Y Acad Sci 979:178-87; discussion 188-96. 2002
    ..in the pressure and flow sensitivities of lymphatic vessels derived from different tissues, such as the thoracic duct and mesenteric lymphatics...
  88. ncbi Pleural fluid analysis in chylous pleural effusion
    Vishal Agrawal
    Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
    Chest 133:1436-41. 2008
    Chyle is a noninflammatory, lymphocyte-predominant fluid that may cause a pleural effusion as a consequence of thoracic duct leakage into the pleural space...
  89. doi Chylothorax and cholesterol pleural effusion
    J Terrill Huggins
    Department of Medicine, Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Semin Respir Crit Care Med 31:743-50. 2010
    ..is defined by the presence of chyle in the pleural space resulting from obstruction or disruption of the thoracic duct or one of its major tributaries...
  90. ncbi Natural orifice transesophageal mediastinoscopy and thoracoscopy
    F F Willingham
    Department of Medicine, Gastrointestinal Unit, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114 3117, USA
    Surg Endosc 22:1042-7. 2008
    ..In addition NOTES esophageal access routes also have the potential to replace conventional thoracoscopic approaches for medial or hilar lesions...
  91. ncbi Late-onset chylothorax after blunt chest trauma at an interval of 20 years: report of a case
    Mitsuhiro Kamiyoshihara
    Department of General Thoracic Surgery, Maebashi Red Cross Hospital, 3 21 36 Asahi cho, Maebashi, Gunma 371 0014, Japan
    Surg Today 38:56-8. 2008
    ..at an interval of 20 years after thoracic vertebrae fractures, who underwent a successful thoracoscopic thoracic duct ligation and pleurodesis...
  92. ncbi The role of lymph factors in lung injury, bone marrow suppression, and endothelial cell dysfunction in a primate model of trauma-hemorrhagic shock
    Edwin A Deitch
    Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
    Shock 22:221-8. 2004
    ..Thus, the three goals of this study were to determine if diversion of thoracic duct lymph reduced T/HS-induced lung injury; to compare the biologic activity of thoracic duct lymph from baboons ..
  93. doi Outcomes of Heimlich valve drainage in dogs
    H Salci
    Department of Surgery, Faculty of Veterinary Medicine, Uludag University, 16059 Bursa, Turkey
    Aust Vet J 87:148-51. 2009
    ..Retrospective study of the outcomes of Heimlich valve drainage in dogs...
  94. ncbi Hydrodynamic regulation of lymphatic transport and the impact of aging
    Anatoliy A Gashev
    Department of Systems Biology and Translational Medicine, Cardiovascular Research Institute Division of Lymphatic Biology, College of Medicine, Texas A and M Health Science Center, 702 SW H K Dodgen Loop, Temple, TX 76504, USA
    Pathophysiology 17:277-87. 2010
    ..We have begun to evaluate the influence of the aging process on lymphatic transport characteristics in the rat thoracic duct. The pressure/stretch-dependent activation of intrinsic pumping is significantly impaired in aged rat thoracic ..
  95. ncbi Transforming growth factor-beta 1 and IL-4 regulate the adhesiveness of Peyer's patch high endothelial venule cells for lymphocytes
    Y H Chin
    Department of Microbiology and Immunology, University of Miami School of Medicine, FL 33101
    J Immunol 148:1106-12. 1992
    ..We have recently shown that the adhesiveness of cultured rat lymph node and PP HEV cells for thoracic duct lymphocytes can be increased significantly by pretreatment with TNF-alpha, IFN-gamma, and IL-4...
  96. ncbi Chylothorax following extended thymectomy for myasthenia gravis
    C S Huang
    Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan
    Thorac Cardiovasc Surg 55:274-6. 2007
    ..Injury to the unseen division of the mediastinal lymphatics and branches from the thoracic duct during extensive dissection of perithymic fat tissue, which is seldom performed in classical thymothymectomy ..
  97. ncbi Hybrid approach to surgical correction of tetralogy of Fallot in all patients with functioning Blalock Taussig shunts
    Kothandam Sivakumar
    Department of Pediatric Cardiology, Apollo Hospital, Colombo, Srilanka
    Catheter Cardiovasc Interv 70:256-64. 2007
    In total surgical correction of tetralogy of Fallot (TOF) with functioning Blalock Taussig shunts (BTS), shunt take down increased surgical time, bleeding, and might injure phrenic and recurrent laryngeal nerve and thoracic duct.
  98. pmc Surgical strategy of complex empyema thoracis
    F J Podbielski
    The University of Illinois at Chicago, Division of Cardiothoracic Surgery, USA
    JSLS 4:287-90. 2000
    ..Proponents of pleural drainage alone, drainage plus fibrinolytic therapy, video-assisted thoracoscopic surgical (VATS) debridement, and open thoracotomy each champion the efficacy of their approach...
  99. pmc Exploring the feasibility of selective depletion of T lymphocyte subsets by whole blood immunoadsorption cytapheresis
    M Belak
    Section of Hematology and Oncology, Department of Medicine, Boston University Medical Center, Boston, MA, USA
    Clin Exp Immunol 150:477-86. 2007
    ..Consequently, the physical removal of circulating leucocytes by thoracic duct drainage, repeated leukapheresis or blood filtration results in T cell depletion and immunosuppression...
  100. ncbi Forty years of publication of transplantation proceedings--the second decade: the cyclosporine revolution
    Barry D Kahan
    Division of Immunology and Organ Transplantation, The University of Texas Health Science Center at Houston Medical School, Houston, Texas 77030, USA
    Transplant Proc 41:1423-37. 2009
    ..In contrast to pre-transplant conditioning by thoracic duct drainage or total lymphoid irradiation, which were too cumbersome for routine execution among the burgeoning ..
  101. ncbi The first series of completely robotic esophagectomies with three-field lymphadenectomy: initial experience
    K H Kernstine
    Department of Thoracic Surgery, City of Hope National Medical Center, 1500 East Duarte Road, Warsaw MOB, Suite 2001G, Duarte, CA 91010 3000, USA
    Surg Endosc 21:2285-92. 2007
    ..This study investigated the use of robotics to perform extended esophageal resection in a series of patients...

Research Grants79

  1. Cholesterol and Lymphatic Transport of Molecules and Cells
    Gwendalyn Randolph; Fiscal Year: 2009
    ..The lymphatic system participates centrally in returning HDL to the bloodstream via the thoracic duct, and it also absorbs lipoproteins directly from the small intestinal villi in the form of chylomicrons...
  2. Cholesterol and Lymphatic Transport of Molecules and Cells
    Melody A Swartz; Fiscal Year: 2010
    ..The lymphatic system participates centrally in returning HDL to the bloodstream via the thoracic duct, and it also absorbs lipoproteins directly from the small intestinal villi in the form of chylomicrons...
  3. Mechanisms of Lymphatic Pump-Enhancement of Immune Function
    LISA HODGE; Fiscal Year: 2009
    ..Now our Preliminary experiments also show that LPT increases leukocyte count in thoracic duct lymph and blood...
  4. Shock, trauma and gut origin of sepsis
    Edwin A Deitch; Fiscal Year: 2010
    ..e. lymph enters subclavian vein via thoracic duct), it would help explain why the lung is the first organ to fail in severely injured patients as well as ..
  5. Shock, trauma and gut origin of sepsis
    Edwin Deitch; Fiscal Year: 2009
    ..e. lymph enters subclavian vein via thoracic duct), it would help explain why the lung is the first organ to fail in severely injured patients as well as ..
  6. Shock, trauma and gut origin of sepsis
    Edwin A Deitch; Fiscal Year: 2010
    ..e. lymph enters subclavian vein via thoracic duct), it would help explain why the lung is the first organ to fail in severely injured patients as well as ..
  7. Shock, trauma and gut origin of sepsis
    Edwin A Deitch; Fiscal Year: 2010
    ..e. lymph enters subclavian vein via thoracic duct), it would help explain why the lung is the first organ to fail in severely injured patients as well as ..
  8. CIRCUIT ANALYSIS OF THE LYMPHATIC SYSTEM
    Robert Drake; Fiscal Year: 1990
    ..Because both liver and the intestinal lymph drain through the thoracic duct, an increase in the flow from the liver could interfere with intestinal lymph flow...
  9. MOLECULAR CHARACTERIZATION OF FAMILIAL LYMPHEDEMA
    Mansoor Sarfarazi; Fiscal Year: 2003
    ..lymphedema-distichiasis syndrome (LDS) in which there is hyperplasia of lymphatics, aplasia or hypoplasia of thoracic duct, and frequent cardiac malformations, in association with double row of eyelashes (distichiasis)...
  10. MOLECULAR CHARACTERIZATION OF FAMILIAL LYMPHEDEMA
    Mansoor Sarfarazi; Fiscal Year: 2001
    ..lymphedema-distichiasis syndrome (LDS) in which there is hyperplasia of lymphatics, aplasia or hypoplasia of thoracic duct, and frequent cardiac malformations, in association with double row of eyelashes (distichiasis)...
  11. MOLECULAR CHARACTERIZATION OF FAMILIAL LYMPHEDEMA
    Mansoor Sarfarazi; Fiscal Year: 2002
    ..lymphedema-distichiasis syndrome (LDS) in which there is hyperplasia of lymphatics, aplasia or hypoplasia of thoracic duct, and frequent cardiac malformations, in association with double row of eyelashes (distichiasis)...
  12. DIETARY DEFICIENCIES AND TUBERCULOSIS VACCINE EFFICACY
    David McMurray; Fiscal Year: 1992
    ..pigs will be investigated by comparing the phenotype and function of lymphocytes in blood, lymph nodes and thoracic duct lymph, and by examining the characteristics of lymphocytes capable of trafficking into a pleural effusion ..
  13. DIETARY DEFICIENCIES AND TUBERCULOSIS VACCINE EFFICACY
    David McMurray; Fiscal Year: 1991
    ..pigs will be investigated by comparing the phenotype and function of lymphocytes in blood, lymph nodes and thoracic duct lymph, and by examining the characteristics of lymphocytes capable of trafficking into a pleural effusion ..
  14. DIETARY DEFICIENCIES AND TUBERCULOSIS VACCINE EFFICACY
    David McMurray; Fiscal Year: 1993
    ..pigs will be investigated by comparing the phenotype and function of lymphocytes in blood, lymph nodes and thoracic duct lymph, and by examining the characteristics of lymphocytes capable of trafficking into a pleural effusion ..
  15. Shock, Trauma and Gut Origin Sepsis
    Edwin Deitch; Fiscal Year: 2004
    ..e. lymph enters subclavian vein via thoracic duct), it would help explain why the lung is the first organ to fail in severely injured patients as well as ..
  16. Shock, Trauma and Gut Origin Sepsis
    Edwin Deitch; Fiscal Year: 2006
    ..e. lymph enters subclavian vein via thoracic duct), it would help explain why the lung is the first organ to fail in severely injured patients as well as ..
  17. Shock, Trauma and Gut Origin Sepsis
    Edwin Deitch; Fiscal Year: 2007
    ..e. lymph enters subclavian vein via thoracic duct), it would help explain why the lung is the first organ to fail in severely injured patients as well as ..
  18. Shock, Trauma and Gut Origin Sepsis
    Edwin Deitch; Fiscal Year: 2005
    ..e. lymph enters subclavian vein via thoracic duct), it would help explain why the lung is the first organ to fail in severely injured patients as well as ..
  19. MECHANISMS OF W-3 FATTY ACID ON ALCOHOLIC HYPERLIPIDEMIA
    Raj Lakshman; Fiscal Year: 1991
    ..in vivo systems involving cannulate of the thoracic duct, jugular vein, carotid artery, and other techniques described in proposal. B...
  20. MECHANISMS OF W-3 FATTY ACID ON ALCOHOLIC HYPERLIPIDEMIA
    Raj Lakshman; Fiscal Year: 1990
    ..in vivo systems involving cannulate of the thoracic duct, jugular vein, carotid artery, and other techniques described in proposal. B...
  21. IMMUNE SURVEILLANCE IN RADIATION CARCINOGENESIS
    Robert Anderson; Fiscal Year: 1980
    ..immune status of the host, particularly with respect to the number of recirculating T cells mobilizable via thoracic duct cannulation...
  22. Integrin-Mediated Development of the Thoracic Duct
    Dean Sheppard; Fiscal Year: 2007
    ..Based on analysis of alpha9 knockout mice, alpha9beta1 plays a critical role in development of the thoracic duct and other lymphatic vessels...
  23. Integrin-Mediated Development of the Thoracic Duct
    Dean Sheppard; Fiscal Year: 2004
    ..Based on analysis of alpha9 knockout mice, alpha9beta1 plays a critical role in development of the thoracic duct and other lymphatic vessels...
  24. Integrin-Mediated Development of the Thoracic Duct
    Dean Sheppard; Fiscal Year: 2005
    ..Based on analysis of alpha9 knockout mice, alpha9beta1 plays a critical role in development of the thoracic duct and other lymphatic vessels...
  25. Integrin-Mediated Development of the Thoracic Duct
    Dean Sheppard; Fiscal Year: 2006
    ..Based on analysis of alpha9 knockout mice, alpha9beta1 plays a critical role in development of the thoracic duct and other lymphatic vessels...
  26. Molecular Mechanisms of Lymphatic Muscle Contraction
    Mariappan Muthuchamy; Fiscal Year: 2005
    ..We will use rat mesenteric and thoracic duct lymphatic vessels for the molecular studies...
  27. ABSORPTION AND METABOLISM OF CAROTENOIDS
    Raj Lakshman; Fiscal Year: 1993
    ..The PI has expertise in the following systems and techniques to accomplish these specific aims: 1. Thoracic duct cannulation technique to quantitatively recover the products of beta-carotene cleavage. 2...
  28. LYMPHOCYTE CHEMOTAXIS
    Norman Anderson; Fiscal Year: 1980
    ..The partially purified material induces chemotactic responses in T-cells from thoracic duct lymph, con-A stimulated lymphoblasts and thymic lymphoma cells, but lacks demonstrable chemoattractant ..
  29. Molecular Mechanisms of Lymphatic Muscle Contraction
    Mariappan Muthuchamy; Fiscal Year: 2006
    ..We will use rat mesenteric and thoracic duct lymphatic vessels for the molecular studies...
  30. Molecular Mechanisms of Lymphatic Muscle Contraction
    Mariappan Muthuchamy; Fiscal Year: 2007
    ..We will use rat mesenteric and thoracic duct lymphatic vessels for the molecular studies...
  31. Molecular Mechanisms of Lymphatic Muscle Contraction
    Mariappan Muthuchamy; Fiscal Year: 2009
    ..We will use rat mesenteric and thoracic duct lymphatic vessels for the molecular studies...
  32. NATURAL KILLER CELLS IN THE LUNG
    Joan Stein Streilein; Fiscal Year: 1990
    ..pulmonary environment the NK cell is subject to local regulatory factors and does not recirculate through the thoracic duct lymph drainage system...
  33. Project 2 - Lymph Flow Enhancement by OMM in Conscious Dogs
    FRED DOWNEY; Fiscal Year: 2004
    ..abdominal edema and evaluate the impact of OMT on this condition, 2) Develop a technique to chronically sample thoracic duct lymph and determine the effects of OMT on lymph chemical composition and immunological properties...
  34. GENERAL CLINICAL RESEARCH CENTER
    Ernest Beutler; Fiscal Year: 1991
    ..The usefulness of thoracic duct drainage in conjunction with immunosuppressive drugs in reversing the autoimmunity of rheumatoid arthritis ..
  35. IMMUNOBIOLOGY OF RAPID EXPULSION
    Robin Bell; Fiscal Year: 1990
    ..Furthermore we have also shown that a unique population (or subpopulations) of thoracic duct lymphocytes present at day 3/4 post infection can adoptively transfer both adult worm rejection, and, in ..
  36. IMMUNOBIOLOGY OF RAPID EXPULSION
    Robin Bell; Fiscal Year: 1992
    ..Furthermore we have also shown that a unique population (or subpopulations) of thoracic duct lymphocytes present at day 3/4 post infection can adoptively transfer both adult worm rejection, and, in ..
  37. IMMUNOBIOLOGY OF RAPID EXPULSION
    Robin Bell; Fiscal Year: 1991
    ..Furthermore we have also shown that a unique population (or subpopulations) of thoracic duct lymphocytes present at day 3/4 post infection can adoptively transfer both adult worm rejection, and, in ..
  38. EFFECTS OF ORTHOTOPIC LIVER TRANSPLANTATION
    Thomas Starzl; Fiscal Year: 1980
    ..b>Thoracic duct fistula as immunosuppressive adjuvant will be added...
  39. Regulatory Mechanisms in Lymphatic Muscle Contraction
    Mariappan Muthuchamy; Fiscal Year: 2010
    ..We will isolated/cannulated vessels from iliac and thoracic duct lymphatics to study the contractile characteristics of lymphatics...
  40. Regulatory Mechanisms in Lymphatic Muscle Contraction
    Mariappan Muthuchamy; Fiscal Year: 2009
    ..We will isolated/cannulated vessels from iliac and thoracic duct lymphatics to study the contractile characteristics of lymphatics...
  41. Regulatory Mechanisms in Lymphatic Muscle Contraction
    Mariappan Muthuchamy; Fiscal Year: 2007
    ..We will isolated/cannulated vessels from iliac and thoracic duct lymphatics to study the contractile characteristics of lymphatics...
  42. CELL-SURFACE MONITORING BY RECIRCULATING LYMPHOCYTES
    Peter Doherty; Fiscal Year: 1980
    ..specific for a particular viral determinant on the mobilizations of T cells specific for that virus in the thoracic duct lymph. 5...
  43. ASSESSMENT OF SUBSTRATE KINETIC ANALYSIS USING TRACERS
    Robert Wolfe; Fiscal Year: 1990
    ..Interstitial fluid measurements will be obtained by sampling from a cannula chronically placed in the thoracic duct of sheep. (2)...
  44. BASOPHILS AND MAST CELLS: ROLE IN IMMUNE REACTIONS
    J Grant; Fiscal Year: 1980
    ..This activity will be made in large quantities by lymphocytes obtained by stimulation of thoracic duct cells of patients in preparation for renal allograft...
  45. Mechanisms of the Age-related Alterations in Lymphatic Pumping
    Anatoliy A Gashev; Fiscal Year: 2010
    ..Mesenteric lymphatics and thoracic duct from 9 and 24 mo rats (Fischer-344 NIA) will be used for all proposed studies...
  46. Mechanisms of the Age-related Alterations in Lymphatic Pumping
    Anatoliy Gashev; Fiscal Year: 2009
    ..Mesenteric lymphatics and thoracic duct from 9 and 24 mo rats (Fischer-344 NIA) will be used for all proposed studies...
  47. Mechanisms of the Age-related Alterations in Lymphatic Pumping
    Anatoliy Gashev; Fiscal Year: 2008
    ..Mesenteric lymphatics and thoracic duct from 9 and 24 mo rats (Fischer-344 NIA) will be used for all proposed studies...
  48. Integrin-Mediated Development of the Thoracic Duct
    Dean Sheppard; Fiscal Year: 2008
    ..Based on analysis of alpha9 knockout mice, alpha9beta1 plays a critical role in development of the thoracic duct and other lymphatic vessels...
  49. Mechanisms of Lymphatic Pump-Enhancement of Immune Function
    LISA MICHELLE HODGE; Fiscal Year: 2010
    ..Our preliminary experiments have shown that LPT increases thoracic duct lymph flow and leukocyte concentrations in both rats and dogs...
  50. MECHANISM AND FUNCTION OF THE VASCULAR MYOGENIC RESPONSE
    Michael Davis; Fiscal Year: 2000
    ....
  51. CYCLOSPORINE PHARMACOLOGY IN CLINICAL TRANSPLANTATION
    Barry Kahan; Fiscal Year: 1991
    ..The combined pharmacokinetic and pharmacodynamic approach will provide a foundation to design, monitor, evaluate and enhance with efficacy of CsA dosing regimens for renal, cardiac, hepatic and pancreatic transplant recipients...
  52. Cellular Mechanisms of Lymphatic Muscle Contractility
    Michael Davis; Fiscal Year: 2009
    ..These studies will investigate which proteins allow these vessels to contract so that specific therapeutic agents can be developed to correct lymphatic pump dysfunction and drainage of edematous tissues. ..
  53. Regulation of Vascular Tone and Ca channels by Integrins
    Michael Davis; Fiscal Year: 2004
    ..In addition, elucidation of a signal transduction pathway between the CaL channel and beta1 integrins will establish a general paradigm for how ion channels are regulated by integrins and ECM. ..
  54. MECHANISMS REGULATING RV O2 BALANCE IN CONSCIOUS
    H Downey; Fiscal Year: 2004
    ..Results will impact treatment of conditions which limit myocardial O2 supply relative to O2 demand. ..
  55. Regulation of Arteriolar Tone & K Channels by Integrins
    Michael Davis; Fiscal Year: 2005
    ..In addition, our results will establish a paradigm for understanding how other ion channels in other tissues may be regulated by integrins. ..
  56. MECHANISM AND FUNCTION OF THE VASCULAR MYOGENIC RESPONSE
    Michael Davis; Fiscal Year: 1992
    ..The results of these experiments will provide new insights into the mechanism and function of the myogenic response at the network, single vessel, and cellular levels...
  57. MECHANISMS REGULATING RV O2 BALANCE IN CONSCIOUS ANIMALS
    H Downey; Fiscal Year: 2003
    ..Results will impact treatment of conditions which limit myocardial O2 supply relative to O2 demand. ..
  58. Molecular Mechanisms of Lymphatic Muscle Contraction
    Mariappan Muthuchamy; Fiscal Year: 2008
    ..We will use rat mesenteric and thoracic duct lymphatic vessels for the molecular studies...
  59. MECHANISM AND FUNCTION OF THE VASCULAR MYOGENIC RESPONSE
    Michael Davis; Fiscal Year: 1993
    ..The results of these experiments will provide new insights into the mechanism and function of the myogenic response at the network, single vessel, and cellular levels...
  60. SHEAR STRESS INDUCED RELEASE OF ENDOTHELIAL NITRIC OXIDE
    Michael Davis; Fiscal Year: 2000
    ....
  61. Regulation of Vascular Tone and Ca channels by Integrins
    Michael Davis; Fiscal Year: 2005
    ..In addition, elucidation of a signal transduction pathway between the CaL channel and beta1 integrins will establish a general paradigm for how ion channels are regulated by integrins and ECM. ..
  62. Proactive Modulation of Strain for Ventricular Recovery
    THERESA FOSSUM; Fiscal Year: 2007
    ..The animal studies will be conducted at the Texas A&M College of Veterinary Medicine by the PI and colleagues who have performed similar animal tests of early stage, assist devices. [unreadable] [unreadable]..
  63. Regulation of Vascular Tone and Ca channels by Integrins
    Michael Davis; Fiscal Year: 2006
    ..In addition, elucidation of a signal transduction pathway between the CaL channel and beta1 integrins will establish a general paradigm for how ion channels are regulated by integrins and ECM. [unreadable] [unreadable]..
  64. Regulation of Vascular Tone and Ca channels by Integrins
    Michael Davis; Fiscal Year: 2009
    ..We will determine how these proteins are modified by the same processes as found in the diseases states and then test the effects they have on vascular ion channels and blood vessel function. ..
  65. Regulation of Vascular Tone and Ca channels by Integrins
    Michael Davis; Fiscal Year: 2005
    ..In addition, elucidation of a signal transduction pathway between the CaL channel and beta1 integrins will establish a general paradigm for how ion channels are regulated by integrins and ECM. ..
  66. MECHANISM AND FUNCTION OF THE VASCULAR MYOGENIC RESPONSE
    Michael Davis; Fiscal Year: 2002
    ....
  67. Regulation of Arteriolar Tone & K Channels by Integrins
    Michael Davis; Fiscal Year: 2003
    ..In addition, our results will establish a paradigm for understanding how other ion channels in other tissues may be regulated by integrins. ..
  68. Regulation of Arteriolar Tone & K Channels by Integrins
    Michael Davis; Fiscal Year: 2004
    ..In addition, our results will establish a paradigm for understanding how other ion channels in other tissues may be regulated by integrins. ..
  69. Regulation of Arteriolar Tone & K Channels by Integrins
    Michael Davis; Fiscal Year: 2006
    ..In addition, our results will establish a paradigm for understanding how other ion channels in other tissues may be regulated by integrins. ..