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Publications
A core gut microbiome in obese and lean twinsPeter J Turnbaugh
Center for Genome Sciences, Washington University School of Medicine, St Louis, Missouri 63108, USA
Nature 457:480-4. 2009....
Development of the human infant intestinal microbiotaChana Palmer
Department of Genetics, Stanford University School of Medicine, Stanford, California, United States of America
PLoS Biol 5:e177. 2007..By the end of the first year of life, the idiosyncratic microbial ecosystems in each baby, although still distinct, had converged toward a profile characteristic of the adult gastrointestinal tract...
Diagnosis of soil-transmitted helminths in the era of preventive chemotherapy: effect of multiple stool sampling and use of different diagnostic techniquesStefanie Knopp
Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
PLoS Negl Trop Dis 2:e331. 2008..In this study, we focused on schoolchildren on Unguja Island, Zanzibar, an area where anthelminthic drugs have been repeatedly administered over the past decade...
Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from fecesErwin G Zoetendal
Wageningen Centre for Food Sciences, Laboratory of Microbiology, Hesselink van Suchtelenweg 4, 6703 CT Wageningen, The Netherlands
Appl Environ Microbiol 68:3401-7. 2002The human gastrointestinal (GI) tract harbors a complex community of bacterial cells in the mucosa, lumen, and feces. Since most attention has been focused on bacteria present in feces, knowledge about the mucosa-associated bacterial ..
Human bocaviruses are highly diverse, dispersed, recombination prone, and prevalent in enteric infectionsAmit Kapoor
Blood Systems Research Institute, and Department of Laboratory Medicine, University of California San Francisco, 270 Masonic Ave, San Francisco, CA 94118, USA
J Infect Dis 201:1633-43. 2010A new species of parvovirus, tentatively named human bocavirus 4 (HBoV4), was genetically characterized. Among 641 feces samples obtained from children and adults, the most commonly detected bocavirus species were, in descending order, ..
Succession of microbial consortia in the developing infant gut microbiomeJeremy E Koenig
Department of Microbiology, Cornell University, Ithaca, NY 14853, USA
Proc Natl Acad Sci U S A 108:4578-85. 2011..This study revealed that seemingly chaotic shifts in the microbiome are associated with life events; however, additional experiments ought to be conducted to assess how different infants respond to similar life events...
Prevalence of Campylobacter, Arcobacter, Helicobacter, and Sutterella spp. in human fecal samples as estimated by a reevaluation of isolation methods for CampylobactersJ Engberg
Department of Gastrointestinal Infections, Division of Diagnostics, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
J Clin Microbiol 38:286-91. 2000..This paper provides evidence for the existence of S. wadsworthensis in human feces from clinical cases of gastrointestinal disorders and in feces from a healthy individual. Furthermore, C...
Diversity of the human intestinal microbial floraPaul B Eckburg
Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Room S 169, 300 Pasteur Drive, Stanford CA 94305 5107, USA
Science 308:1635-8. 2005..We examined 13,355 prokaryotic ribosomal RNA gene sequences from multiple colonic mucosal sites and feces of healthy subjects to improve our understanding of gut microbial diversity...
The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjectsAnna Kassinen
Department of Basic Veterinary Sciences, Division of Microbiology and Epidemiology, University of Helsinki, Helsinki, Finland
Gastroenterology 133:24-33. 2007..Our objective was to characterize putative differences in gastrointestinal microbiota between patients with IBS and control subjects. These differences could potentially have a causal relationship with the syndrome...
Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndromeC Tana
Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Neurogastroenterol Motil 22:512-9, e114-5. 2010..We hypothesized in this study that altered GI microbiota contribute to IBS symptoms through increased levels of organic acids...
Towards the human intestinal microbiota phylogenetic coreJulien Tap
INRA, UEPSD, UR910, 78350 Jouy en Josas, France
Environ Microbiol 11:2574-84. 2009..Its role in human health deserves further study...
Low counts of Faecalibacterium prausnitzii in colitis microbiotaH Sokol
UEPSD, INRA, Jouy en Josas, France
Inflamm Bowel Dis 15:1183-9. 2009..The aim was to compare the fecal microbiota composition of patients with colitis to that of healthy subjects (HS)...
Dysbiosis of fecal microbiota in Crohn's disease patients as revealed by a custom phylogenetic microarraySeungha Kang
Preventative Health National Research Flagship, CSIRO, St Lucia, QLD, Australia
Inflamm Bowel Dis 16:2034-42. 2010....
Metagenomic analysis of the human distal gut microbiomeSteven R Gill
Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
Science 312:1355-9. 2006..Thus, humans are superorganisms whose metabolism represents an amalgamation of microbial and human attributes...
Gastrointestinal microbiota in irritable bowel syndrome: present state and perspectivesAnne Salonen
Department of Veterinary Biosciences, Veterinary Microbiology and Epidemiology, University of Helsinki, PO Box 66, FI 00014 Helsinki, Finland
Microbiology 156:3205-15. 2010..Finally, we discuss the future outlook for research avenues and candidate microbial biomarkers that may eventually be used in IBS diagnosis...
Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCRErja Malinen
Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine, Section of Microbiology, P.O. Box 66, FIN-00014 University of Helsinki, Finland
Am J Gastroenterol 100:373-82. 2005..Increasing microbial DNA sequence information will further allow designing of new real-time PCR assays for a more extensive analysis of intestinal microbes in IBS...
Early differences in fecal microbiota composition in children may predict overweightMarko Kalliomaki
Functional Foods Forum and Program on Health Biosciences and the Department of Pediatrics, University of Turku, Turku, Finland
Am J Clin Nutr 87:534-8. 2008..Experimental studies suggest that gut microbiota deviations predispose toward energy storage and obesity...
Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profilesJane McCarthy
Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
Gastroenterology 128:541-51. 2005....
Relative contribution of day-to-day and intra-specimen variation in faecal egg counts of Schistosoma mansoni before and after treatment with praziquantelJ Utzinger
Swiss Tropical Institute, Basel
Parasitology 122:537-44. 2001..We conclude that diagnostic sensitivity in high transmission areas is maximized by making several stool readings on several days, but examining 1 stool specimen several times can make reasonable estimates of infection intensity...
Gut microbiota composition and development of atopic manifestations in infancy: the KOALA Birth Cohort StudyJohn Penders
Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
Gut 56:661-7. 2007..We examined gut microbiota composition in early infancy and the subsequent development of atopic manifestations and sensitisation...
16S rRNA gene-based analysis of fecal microbiota from preterm infants with and without necrotizing enterocolitisYunwei Wang
Department of Medicine, University of Chicago, Chicago, IL 60637, USA
ISME J 3:944-54. 2009..Our results suggest that NEC is associated with severe lack of microbiota diversity that may accentuate the impact of single dominant microorganisms favored by empiric and widespread use of antibiotics...
Organismal, genetic, and transcriptional variation in the deeply sequenced gut microbiomes of identical twinsPeter J Turnbaugh
Center for Genome Sciences, Washington University School of Medicine, St Louis, MO 63108, USA
Proc Natl Acad Sci U S A 107:7503-8. 2010..g., predicted cellulases, dockerins), and transcriptional activities. These results provide an expanded perspective about features that make each of us unique life forms and directions for future characterization of our gut ecosystems...
The burden of polyparasitism among primary schoolchildren in rural and farming areas in ZimbabweN Midzi
National Institute of Health Research, Box CY 573, Causeway, Harare, Zimbabwe
Trans R Soc Trop Med Hyg 102:1039-45. 2008....
Molecular monitoring of succession of bacterial communities in human neonatesChristine F Favier
Laboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University, 6703 CT Wageningen, The Netherlands
Appl Environ Microbiol 68:219-26. 2002..Clone libraries of amplified 16S rDNA fragments from baby feces were constructed, and these libraries allowed identification of the bacterial types by comparative DNA sequence ..
Estimating the sensitivity and specificity of Kato-Katz stool examination technique for detection of hookworms, Ascaris lumbricoides and Trichuris trichiura infections in humans in the absence of a 'gold standard'M R Tarafder
Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
Int J Parasitol 40:399-404. 2010..lumbricoides and T. trichiura. Low sensitivity of the Kato-Katz for detection of hookworm infection may be related to rapid degeneration of delicate hookworm eggs with time...
Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferersLotta Krogius-Kurikka
Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine, PO Box 66, FI 00014 University of Helsinki, Helsinki, Finland
BMC Gastroenterol 9:95. 2009..The method allowed microbial community analysis on all levels of microbial genomic guanine plus cytosine (G+C) content, including high G+C bacteria...
Factors influencing the composition of the intestinal microbiota in early infancyJohn Penders
Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, PO Box 616, 6200 MD Maastricht, Netherlands
Pediatrics 118:511-21. 2006..The aim of this study was to examine the contribution of a broad range of external influences to the gut microbiotic composition in early infancy...
Evaluation of the bacterial diversity in the feces of cattle using 16S rDNA bacterial tag-encoded FLX amplicon pyrosequencing (bTEFAP)Scot E Dowd
USDA ARS Livestock Issues Research Unit, Lubbock, TX 79403, USA
BMC Microbiol 8:125. 2008..We have evaluated the microbiome from the feces of 20 commercial, lactating dairy cows.
A novel bocavirus associated with acute gastroenteritis in Australian childrenJane L Arthur
Infectious Diseases Laboratories, Institute of Medical and Veterinary Science, Adelaide, Australia
PLoS Pathog 5:e1000391. 2009..7%), and it was not associated with AGE. HBoV2 and HBoV3 are newly discovered bocaviruses, of which HBoV2 is the thirdmost-prevalent virus, after rotavirus and astrovirus, associated with pediatric AGE in this study...
Real-time PCR quantitation of clostridia in feces of autistic childrenYuli Song
Research Service, VA Medical Center West Los Angeles, Los Angeles, California 90073, USA
Appl Environ Microbiol 70:6459-65. 2004..8 x 10(8) CFU/g in controls; respectively). More subjects need to be studied. The assay is a rapid and reliable method, and it should have great potential for quantitation of other bacteria in the intestinal tract...
Early intestinal bacterial colonization and necrotizing enterocolitis in premature infants: the putative role of ClostridiumMarie France de la Cochetiere
INSERM Unité 539, CHU Hotel Dieu, 44035 Nantes cedex 1, France
Pediatr Res 56:366-70. 2004....
The microbiology of butyrate formation in the human colonSusan E Pryde
Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
FEMS Microbiol Lett 217:133-9. 2002....
Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibioticRubhana Raqib
International Centre for Diarrhoeal Disease Research Bangladesh, Centre for Health and Population Research, Dhaka 1212, Bangladesh
Proc Natl Acad Sci U S A 103:9178-83. 2006....
A newly identified bocavirus species in human stoolAmit Kapoor
Blood Systems Research Institute and Department of Laboratory Medicine, University of California, San Francisco, CA 94118, USA
J Infect Dis 199:196-200. 2009..Further studies are necessary to identify anatomical sites of HBoV2 replication and potential associations with clinical symptoms or disease...
Comparing diagnostic accuracy of Kato-Katz, Koga agar plate, ether-concentration, and FLOTAC for Schistosoma mansoni and soil-transmitted helminthsDominik Glinz
Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
PLoS Negl Trop Dis 4:e754. 2010..Accurate diagnosis is crucial for patient management, drug efficacy evaluations, and monitoring of large-scale community-based control programs...
Chimpanzee reservoirs of pandemic and nonpandemic HIV-1Brandon F Keele
Departments of Medicine and Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA
Science 313:523-6. 2006..These findings establish P. t. troglodytes as a natural reservoir of HIV-1...
Long-term ecological impacts of antibiotic administration on the human intestinal microbiotaCecilia Jernberg
Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden
ISME J 1:56-66. 2007....
Diet-induced metabolic improvements in a hamster model of hypercholesterolemia are strongly linked to alterations of the gut microbiotaInés Martínez
Department of Food Science and Technology, University of Nebraska, Lincoln, 68583 0919, USA
Appl Environ Microbiol 75:4175-84. 2009..This study provides evidence that modulation of the gut microbiota-host metabolic interrelationship by dietary intervention has the potential to improve mammalian cholesterol homeostasis, which has relevance for cardiovascular health...
The Firmicutes/Bacteroidetes ratio of the human microbiota changes with ageD Mariat
INRA, U910, Unité d Ecologie et du Système Digestif, Domaine de Vilvert, 78350 Jouy en Josas, France
BMC Microbiol 9:123. 2009..Applying current molecular methods is necessary to surmount the limitations of classical culturing techniques in order to obtain an accurate description of the microbiota composition...
Stool form scale as a useful guide to intestinal transit timeS J Lewis
University Dept of Medicine, Bristol Royal Infirmary, UK
Scand J Gastroenterol 32:920-4. 1997..We set out to assess the responsiveness of the Bristol stool form scale to change in transit time...
Evolution of mammals and their gut microbesRuth E Ley
Center for Genome Sciences, Washington University School of Medicine, St Louis, MO 63108, USA
Science 320:1647-51. 2008....
Clinical and molecular epidemiology of human bocavirus in respiratory and fecal samples from children in Hong KongSusanna K P Lau
State Key Laboratory of Emerging Infectious Diseases, University of Hong Kong, Hong Kong, China
J Infect Dis 196:986-93. 2007..We conducted the first systematic prospective clinical and molecular study using nasopharyngeal aspirates (NPAs) and fecal samples...
Shotgun metaproteomics of the human distal gut microbiotaNathan C Verberkmoes
Oak Ridge National Laboratory, Chemical and Life Sciences Divisions, Oak Ridge, TN, USA
ISME J 3:179-89. 2009..Several unknown proteins represented previously undescribed microbial pathways or host immune responses, revealing a novel complex interplay between the human host and its associated microbes...
Viral agents of acute gastroenteritis in hospitalized children in GreeceS Levidiotou
Department of Microbiology, Medical School, University of Ioannina, Ioannina, Greece
Clin Microbiol Infect 15:596-8. 2009....
Influence of early gut microbiota on the maturation of childhood mucosal and systemic immune responsesY M Sjögren
Department of Immunology, Wenner Gren Institute, Stockholm University, Stockholm, Sweden
Clin Exp Allergy 39:1842-51. 2009..Although animal and in vitro studies emphasize the role of the commensal gut microbiota in the development of the immune system, the influence of the gut microbiota on immune development in infants is unclear...
Detection of novel astroviruses in urban brown rats and previously known astroviruses in humansDaniel K W Chu
State Key Laboratory for Emerging Infectious Diseases, Department of Microbiology and the Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong SAR
J Gen Virol 91:2457-62. 2010..These rat astroviruses were phylogenetically related to recently discovered human astroviruses MLB1 and MLB2, suggesting that the MLB viruses and these novel rat astroviruses may share a common ancestor...
Identification and characterization of a new bocavirus species in gorillasAmit Kapoor
Center for Infection and Immunity, Columbia University, New York, New York, United States of America
PLoS ONE 5:e11948. 2010..GBoV is the first non-human primate bocavirus identified and provides new insights into the genetic diversity and evolution of this highly prevalent and recently discovered group of parvoviruses...
Asymptomatic deer excrete infectious prions in faecesGULTEKIN TAMGUNEY
Institute for Neurodegenerative Diseases, University of California, San Francisco, California 94143 USA
Nature 461:529-32. 2009....
Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic miceAndrew L Goodman
Center for Genome Science and Systems Biology, Washington University School of Medicine, St Louis, MO 63108, USA
Proc Natl Acad Sci U S A 108:6252-7. 2011....
Novel circular DNA viruses in stool samples of wild-living chimpanzeesOlga Blinkova
Blood Systems Research Institute, San Francisco and the Department of Laboratory Medicine, University of California, San Francisco, CA, USA
J Gen Virol 91:74-86. 2010..Further metagenomic studies of animal samples will greatly increase our knowledge of viral diversity and evolution...
Longitudinal investigation of the faecal microbiota of healthy full-term infants using fluorescence in situ hybridization and denaturing gradient gel electrophoresisLaure C Roger
Microbial Ecology and Health Group, Food Microbial Sciences Unit, Department of Food and Nutritional Sciences, University of Reading, Whiteknights Campus, PO Box 226, Reading RG6 6AP, UK
Microbiology 156:3317-28. 2010..These data can be of help to future clinical trials (e.g. targeted weaning products) to organize protocols and obtain a more accurate outline of the changes and dynamics of the infant GI microbiota...
Patterns and risk factors of helminthiasis and anemia in a rural and a peri-urban community in Zanzibar, in the context of helminth control programsStefanie Knopp
Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
PLoS Negl Trop Dis 4:e681. 2010..The purpose of this study was to determine patterns and risk factors of helminth infections and anemia in a rural and a peri-urban community of Zanzibar, Tanzania, in the context of national helminth control programs...
Human helminth co-infection: no evidence of common genetic control of hookworm and Schistosoma mansoni infection intensity in a Brazilian communityRachel L Pullan
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Int J Parasitol 40:299-306. 2010....
The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Cote d'IvoireMichael B Zimmermann
Institute of Food, Nutrition and Health, Swiss Federal Institute of Technology Zurich, Zurich, Switzerland
Am J Clin Nutr 92:1406-15. 2010..Thus, increasing colonic iron could select gut microbiota for humans that are unfavorable to the host...
Intestinal schistosomiasis in mothers and young children in Uganda: investigation of field-applicable markers of bowel morbidityMartha Betson
Wolfson Wellcome Biomedical Laboratories, Department of Zoology, Natural History Museum, London, United Kingdom
Am J Trop Med Hyg 83:1048-55. 2010..0001) and mothers (n = 448, OR = 1.95, P = 0.004). Fecal occult blood appears to be useful for measuring morbidity associated with intestinal schistosomiasis and could be used in assessing the impact of control programs upon disease...
Klassevirus 1, a previously undescribed member of the family Picornaviridae, is globally widespreadLori R Holtz
Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
Virol J 6:86. 2009..In an effort to identify novel viruses that may be causal agents of diarrhea, we used high throughput mass sequencing to analyze stool samples collected from patients with acute diarrhea...
Detection of sub-clinical CWD infection in conventional test-negative deer long after oral exposure to urine and feces from CWD+ deerNicholas J Haley
Department of Microbiology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America
PLoS ONE 4:e7990. 2009..CWD detection methods, we have previously identified infectious prions in saliva and blood but not urine or feces of CWD+ donors...
Metagenomic analyses of viruses in stool samples from children with acute flaccid paralysisJoseph G Victoria
Blood Systems Research Institute, San Francisco, California 94118, USA
J Virol 83:4642-51. 2009....
MM3-ELISA detection of Fasciola hepatica coproantigens in preserved human stool samplesFlorencio M Ubeira
Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Santiago de Compostela, Santiago de Compostela, Spain
Am J Trop Med Hyg 81:156-62. 2009..We concluded that the MM3-COPRO ELISA combined with the use of CoproGuard may be a very useful tool for the diagnosis of human fascioliasis...
Combined PCR-DGGE fingerprinting and quantitative-PCR indicates shifts in fecal population sizes and diversity of Bacteroides, bifidobacteria and Clostridium cluster IV in institutionalized elderlyJutta Zwielehner
Department of Nutritional Sciences, University of Vienna, Austria
Exp Gerontol 44:440-6. 2009..This study aimed at determining ageing-related shifts in diversity and composition of key members of the fecal microbiota by comparing institutionalized elderly (n = 17, 78-94 years) and young volunteers (n = 17, 18-31 years)...
Factors associated with defecation patterns in 0-24-month-old childrenVildan Taylan Tunc
Department of Family Practice, Ankara Numune Research and Education Hospital, Ankara, Turkey
Eur J Pediatr 167:1357-62. 2008..3% of these infants defecated less than once a day...
Bat guano virome: predominance of dietary viruses from insects and plants plus novel mammalian virusesLinlin Li
Blood Systems Research Institute 270 Masonic Ave, San Francisco, CA 94118, USA
J Virol 84:6955-65. 2010..Viral metagenomics is a useful tool for genetically characterizing viruses present in animals with the known capability of direct or indirect viral zoonosis to humans...
Occurrence and characterization of verocytotoxigenic Escherichia coli (VTEC) strains from dairy farms in TrinidadR R Roopnarine
Faculty of Medical Sciences, School of Veterinary Medicine, University of the West Indies, St Augustine, Trinidad and Tobago
Zoonoses Public Health 54:78-85. 2007..In addition, the demonstration of VTEC strains in humans, VT gene in faecal samples and E. coli isolates as well as non-O157 VTEC strains of E. coli are being documented for the first time in the country...
Rectoanal junction colonization of feedlot cattle by Escherichia coli O157:H7 and its association with supershedders and excretion dynamicsRowland N Cobbold
Field Disease Investigation Unit, College of Veterinary Medicine, Washington State University, Pullman, Washington 99164 6610, USA
Appl Environ Microbiol 73:1563-8. 2007..An improved understanding of individual and population transmission dynamics of E. coli O157:H7 can be used to develop preslaughter- and slaughter-level interventions that reduce contamination of the food chain...
Prevalence and preliminary genetic characterization of Cryptosporidium spp. isolated from asymptomatic heifers in Galicia (NW, Spain)Jose A Castro-Hermida
Laboratorio de Parasitologia, Centro de Investigaciones Agrarias de Mabegondo, Carretera C 542 de Betanzos a Mesón do Vento, Km 7, 5 CP 15318, Abegondo A Coruña, Galicia, Espana
J Eukaryot Microbiol 53:S22-3. 2006
Factors associated with shedding of Cryptosporidium parvum versus Cryptosporidium bovis among dairy cattle in New York StateSimon R Starkey
Section of Epidemiology, Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Am Vet Med Assoc 229:1623-6. 2006..Findings also lend credence to the theory that C bovis may be more host adapted and thus less pathogenic to dairy cattle than C parvum...
Field study of the efficacy of halofuginone and decoquinate in the treatment of cryptosporidiosis in veal calvesM Lallemand
Centre Hospitalier Universitaire Vétérinaire de St Hyacinthe, 3200 rue Sicotte, St Hyacinthe, Québec J25 7C6, SC, Canada
Vet Rec 159:672-6. 2006..However, unlike decoquinate, halofuginone significantly reduced the excretion of oocysts on day 7 (P<0.0001), and decoquinate increased the average daily weight gain of the calves (P=0.049)...
Variants of eae and stx genes of atypical enteropathogenic Escherichia coli and non-O157 Shiga toxin-producing Escherichia coli from calvesS A Wani
Bacteriology Laboratory, Division of Veterinary Microbiology and Immunology, SK University of Agricultural Sciences and Technology of Kashmir, Shuhama Alusteng, Srinagar, India
Lett Appl Microbiol 45:610-5. 2007..To determine the subtypes of stx and eae genes of Shiga toxin-producing Escherichia coli (STEC) and enteropathogenic Escherichia coli (EPEC) from calves and to ascertain the typical and atypical nature of EPEC...
[Internal parasites of cattle in select Western Pomerania farms]Bogumiła Pilarczyk
Katedra Higieny Zwierzat i Profilaktyki, Akademia Rolnicza, ul Doktora Judyma 6, 71 460 Szczecin
Wiad Parazytol 48:383-90. 2002..ranged from 5.5 to 23.4%, gastro-intestinal nematodes ranged from 12.7 to 42.6%. In calves, the overall prevalence Eimeria sp. was ranged from 10.0 to 36.8% oocysts and Cryptosporidium sp. 22.8%...
Sensitivity of an immunomagnetic-separation-based test for detecting Escherichia coli O26 in bovine fecesL M Hall
Scottish Agricultural College, Stratherrick Rd, Inverness IV2 4JZ, United Kingdom
Appl Environ Microbiol 72:7260-3. 2006..The effective dose of E. coli O26 for an 80% test sensitivity (ED(80)) was 1.0 x 10(4) CFU g(-1) feces (95% confidence interval, 4.7 x 10(3) to 2.4 x 10(4)). Differences in test sensitivity between different E...
Shiga toxin-producing Escherichia coli in healthy young beef steers from Argentina: prevalence and virulence propertiesLelis Meichtri
, , , C.C. 77. C.P. (B1708WAB, , Buenos Aires, Argentina
Int J Food Microbiol 96:189-98. 2004..This research indicates that young steers from the main beef-producing area of Argentina are an important reservoir of STEC strains; however, its importance as agents of human diseases in our country has still to be established...
Molecular epidemiology of bovine noroviruses in South KoreaSang Ik Park
Bio therapy Human Resources Center, College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, South Korea
Vet Microbiol 124:125-33. 2007..In conclusion, BNoV infections are endemic and there are two distinct genotypes with GIII-2 being the main genotype circulating in the calf population in South Korea...
Preventive and therapeutic efficacy of halofuginone-lactate against Cryptosporidium parvum in spontaneously infected calves: a centralised, randomised, double-blind, placebo-controlled studyPavel Klein
Institute of Animal Science, Pratelstvi 815, Praha Uhrineves, CZ 10401, Czech Republic
Vet J 177:429-31. 2008..The results of this study confirm the anticryptosporidial activity of HFL in calves, but show that the outcome of infection following preventive treatment is comparable to that observed in calves treated after the onset of symptoms...
Antimicrobial resistance in generic fecal Escherichia coil obtained from beef cattle on arrival at the feedlot and prior to slaughter, and associations with volume of total individual cattle antimicrobial treatments in one western Canadian feedlotSylvia L Checkley
Food Safety Division, Alberta Agriculture and Food, 116B, 6909 116 Street, Edmonton, Alberta T6H 4P2
Can J Vet Res 72:101-8. 2008..Only 1 ADD(Feedlot) was given in the 100 days immediately prior to slaughter. There were no associations found between antimicrobial use and antimicrobial resistance in this study...
Prevalence of antimicrobial resistance in fecal generic Escherichia coil isolated in western Canadian beef herds. Part II--cows and cow-calf pairsSheryl P Gow
Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4
Can J Vet Res 72:91-100. 2008..16), cow age (P = 0.14), or previous cow treatment (P = 0.56). In the calves, resistance to at least 1 antimicrobial was not predicted by whether or not its dam was resistant to at least 1 antimicrobial (P = 0.36)...
Prevalence of antimicrobial resistance in fecal generic Escherichia coil isolated in western Canadian cow-calf herds. Part I--beef calvesSheryl P Gow
Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4
Can J Vet Res 72:82-90. 2008..Calves < or = 3 days of age were less likely to be resistance positive than calves > 10 days of age...
Prevalence and characterization of verotoxin-producing Escherichia coli (VTEC) in cattle from an Ontario abattoirMusafiri Karama
Department of Pathobiology, University of Guelph, Guelph, Ontario N1G 2W1
Can J Vet Res 72:297-302. 2008..Cultures of rectal feces from 500 animals were screened for VT by an enzyme-linked immunosorbent assay (ELISA) and by polymerase chain ..
The distribution of Fasciola hepatica and Fasciola gigantica within southern Tanzania--constraints associated with the intermediate hostS M Walker
School of Biological Sciences, The Queen s University of Belfast, 97 Lisburn Road, Belfast BT9 7BL
Parasitology 135:495-503. 2008..natalensis was confirmed by molecular data along with its preferred fasciolid parasite, F. gigantica. Analysis based on a 618 bp sequence of the 28S rRNA gene did not reveal the presence of hybrid fasciolids in our fluke samples...
Effect of a vaccine product containing type III secreted proteins on the probability of Escherichia coli O157:H7 fecal shedding and mucosal colonization in feedlot cattleR E Peterson
Department of Animal Science, University of Nebraska Lincoln, Lincoln, Nebraska 68583 0905, USA
J Food Prot 70:2568-77. 2007..coli O157:H7 in feces, are colonized by this organism in the terminal rectum, or develop a humoral response to the respective antigens...
Influence of processed grains on fecal pH, starch concentration, and shedding of Escherichia coli O157 in feedlot cattleB E Depenbusch
Department of Animal Sciences and Industry, Kansas State University, Manhattan 66505, USA
J Anim Sci 86:632-9. 2008..coli O157. Beginning on d 13, heifers were sampled (feces and RAMS) weekly to monitor fecal pH and starch concentration, and prevalence of E. coli O157. Prevalence of E...
Shiga toxin gene-containing Escherichia coli from cattle and diarrheic children in the pastoral systems of southwestern UgandaSamuel Majalija
Division of Medical Microbiology, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, South Africa
J Clin Microbiol 46:352-4. 2008..The STEC strains belonged to a variety of different serogroups, and 70% of the strains were positive for the intimin gene, eae. STEC strains from two of the children were closely related to bovine strains...
Antimicrobial use on 24 beef farms in OntarioCarolee A Carson
Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, 160 Research Lane, Unit 103, Guelph, Ontario N1G 5B2
Can J Vet Res 72:109-18. 2008....
Epidemiological studies of parasitic gastrointestinal nematodes, cestodes and coccidia infections in cattle in the highveld and lowveld communal grazing areas of ZimbabweD M Pfukenyi
Clinical Veterinary Studies, Faculty of Veterinary Science, University of Zimbabwe, P O Box MP167, Mt Pleasant, Harare, Zimbabwe
Onderstepoort J Vet Res 74:129-42. 2007..These findings are discussed with reference to their relevance for strategic control of GI parasites in cattle in communal grazing areas of Zimbabwe...
Presence of non-O157 Shiga toxin-producing Escherichia coli in feces from feedlot cattle in Alberta and absence on corresponding beef carcassesDavid G Renter
Department of Diagnostic Medicine Pathobiology, 307 Coles Hall, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas 66506, USA
Can J Vet Res 71:230-5. 2007..Non-O157 STEC were recovered from feces from 12 (14%) of the 84 pens and 12 (57%) of the 21 feedlots by examination of 1 E...
Antimicrobial resistance in generic fecal Escherichia coli from 29 beef farms in OntarioCarolee A Carson
Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, 160 Research Lane, Unit 103, Guelph, Ontario N1G 5B2 Carson
Can J Vet Res 72:119-28. 2008....
[Influence of animal breeding manner on the occurence of internal parasites]Konstanty Romaniuk
, , , Olsztyn
Wiad Parazytol 50:647-51. 2004..The animals surveyed were infected chiefly with nematodes and to a considerably smaller degree with tapeworms and coccidia...
Screening procedure from cattle feces and the prevalence of Escherichia coli O157:H7 in Taiwan dairy cattleY L Lin
Institute of Veterinary Medicine, National Taiwan University, Taipei, ROC
J Microbiol Immunol Infect 34:17-24. 2001A procedure has been established for screening Escherichia coli O157:H7 from bovine feces. It consists of four steps: enrichment, selective culture, phenotyping and genotyping...
Evaluation of the chemoprophylactic efficacy of 10% long acting injectable moxidectin against gastrointestinal nematode infections in calves in BelgiumT Geurden
Department of Virology, Parasitology and Immunology, Ghent University, Merelbeke, Belgium
Vet Parasitol 120:331-8. 2004..5% compared to the control group, while the reduction in C. oncophora worm burden was 57%. An additional benefit of the long acting parasitological control, was reduced pasture contamination...
Efficacy of halofuginone lactate in the prevention of cryptosporidiosis in suckling calvesD Lefay
, Les Algorithmes, Saint Aubin, France
Vet Rec 148:108-12. 2001..5 per cent of the calves in the placebo group having liquid diarrhoea compared with 11.5 per cent in the halofuginone lactate group. The treatment was well tolerated and easily administered...
Shiga toxin-producing Escherichia coli in the feces of Alberta feedlot cattleDavid G Renter
Agri Food Systems Branch, Food Safety Division, Alberta Agriculture, Food and Rural Development, Edmonton, Alberta
Can J Vet Res 68:150-3. 2004..Bacterial culture techniques commonly used to detect E. coli O157:H7 will not detect other STEC serotypes. Feces from cattle and other animals are a source of O157:H7 and other pathogenic serotypes of STEC...
High numbers of Shiga toxin-producing Escherichia coli found in bovine faeces collected at slaughter in JapanHiroshi Fukushima
Shimane Prefectural Institute of Public Health and Environmental Science, 582 Nishihamasada, Matsue, Shimane 690 0122, Japan
FEMS Microbiol Lett 238:189-97. 2004..The presence of a high-carriage animal at the abattoir increases the potential risk of meat contamination during the slaughtering process, regardless of faecal pH...
Ascophyllum nodosum supplementation: a preharvest intervention for reducing Escherichia coli O157:H7 and Salmonella spp. in feedlot steersK W Braden
Department of Animal and Food Sciences, Texas Tech University, Lubbock, Texas 79409, USA
J Food Prot 67:1824-8. 2004..Results from this study indicate that 2% Tasco-14 supplementation in feedlot cattle diets reduces EHEC O157 and EHEC O157:H7 prevalence on hide swabs and in fecal samples and may suppress increases in Salmonella spp...
Shedding patterns of verocytotoxin-producing Escherichia coli strains in a cohort of calves and their dams on a Scottish beef farmD J Shaw
Veterinary Epidemiology Group, Centre for Tropical and Veterinary Medicine, College of Medicine and Veterinary Medicine, University of Edinburgh, Roslin, Midlothian, United Kingdom
Appl Environ Microbiol 70:7456-65. 2004..No association between calf diarrhea and any of the VTEC serogroups was identified...
Prevalence, enumeration and strain variation of Arcobacter species in the faeces of healthy cattle in BelgiumEllen Van Driessche
Department of Veterinary Public Health and Food Safety, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
Vet Microbiol 105:149-54. 2005..Characterization of the 164 isolates showed a large heterogeneity and animals could be colonized with more than one genotype...
Escherichia coli O4:NM associated with an outbreak of calf diarrhoeaS A Wani
Division of Veterinary Microbiology and Immunology, S K University of Agricultural Sciences and Technology of Kashmir (SKUAST-K, Rotavirus Laboratory, Shuhama, Alusteng) Srinagar 190006, India
Vet J 169:300-2. 2005
The point prevalence of gastro-intestinal parasites in calves, sheep and goats in Magadi division, south-western KenyaM W Maichomo
Kenya Trypanosomiasis Research Institute, P.O. Box 362, Kikuyu, Kenya
Onderstepoort J Vet Res 71:257-61. 2004..These findings indicate that viable internal parasite control should be implemented in the study area in order to increase the productivity of the livestock there...
A longitudinal study of Escherichia coli O157 in cattle of a Dutch dairy farm and in the farm environmentJ M Schouten
Quantitative Veterinary Epidemiology, Wageningen Institute of Animal Sciences, Wageningen University and Research Centre, P O Box 338, 6700 AH Wageningen, The Netherlands
Vet Microbiol 107:193-204. 2005..0055). There was no significant association between the results of the LPS-ELISA on serum samples from dairy cows and their O157 status...
Prevalence of Cryptosporidium parvum infection in southwestern Ontario and its association with diarrhea in neonatal dairy calvesLise A Trotz-Williams
Department of Population Medicine Ontario Veterinary College, University of Guelph, Guelph, Ontario
Can Vet J 46:349-51. 2005..This parasite appears to be common in Ontario dairy calves and important as a cause of dairy calf scours in the province...
Occurrence and characteristics of enterohemorrhagic Escherichia coli O157 in calves associated with diarrhoeaS J Kang
College of Veterinary Medicine and Bio-Safety Research Institute, Chonbuk National University, Chonju 561-756, Republic of Korea
Vet Microbiol 98:323-8. 2004....
[Coccidiosis causes diarrhea in calves in the pasture. Pasture coccidiosis caused by Eimeria alabamensis]J J Snoep
Tijdschr Diergeneeskd 129:158-60. 2004..In the manure large numbers Eimeria alabamensis oocysts were found. This infection is considered as a case of coccidial diarrhoea in (older) calves at pasture...
Environmental sources and transmission of Escherichia coli O157 in feedlot cattleJ Van Donkersgoed
11 Bruns Road, Lacombe, Alberta T4L 1P1, Lakeside Research, Box 800, Brooks, Alberta
Can Vet J 42:714-20. 2001..Escherichia coli O157:H7 was isolated in preslaughter pens of cattle from feces (0.8%), feedbunks (1.7%), water troughs (12%), and incoming water supplies (4...
Research Grants
- NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINSFrances Walker; Fiscal Year: 2009..in obtaining an ample blood meal, and thus make more likely the transmission of the trypanosome from the insect feces to humans...
- NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINSFrances Walker; Fiscal Year: 2009..in obtaining an ample blood meal, and thus make more likely the transmission of the trypanosome from the insect feces to humans...
- NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINSFRANCES ANN WALKER; Fiscal Year: 2010..in obtaining an ample blood meal, and thus make more likely the transmission of the trypanosome from the insect feces to humans...
- Hepatic Cholesteryl Ester Metabolism and Cholesterol EliminationShobha Ghosh; Fiscal Year: 2010..ultimate elimination of cholesterol from the body as free cholesterol (FC) or bile acids that are excreted in the feces. Cholesterol associated with excess unmodified LDL as well as the cholesterol removed from the peripheral organs ..
- Prophylactic and Therapeutic Immunization against H. pylori in Rhesus MacaquesJAY SOLNICK; Fiscal Year: 2007..We will also examine BabA- and BabB-specific antibodies in serum, gastric juice, and feces, as well as histopathology to evaluate inflammation and the topography of infection...
- NOC in processed meat as a likely cause of colon cancerSidney S Mirvish; Fiscal Year: 2010..ANC prepared from hot dog patties manufactured under standard conditions and those giving minimum ANC levels, from feces of rats fed NaNO2 or hot dogs, and from the reaction of glucose with glycine and other amino acids...
- Hantavirus Vaccines Based On Nonreplicating AdenovirusesDavid Johnson; Fiscal Year: 2005Hantaviruses are spread from infected rodents to man in dust particles derived from rodent urine, feces or saliva. Old World hantaviruses were first recognized during the Korean war, infecting thousands of U.S. troops with 10% mortality...
- Molecular Mechanisms of Chemoprevention: NRF2 SignalingThomas Kensler; Fiscal Year: 2009..of isotope-dilution mass spectrometry for the quantitation of aflatoxin biomarkers in liver, blood, urine and feces in order to develop for the first time a comprehensive mass balance for the fate of the ultimate carcinogen, exo-..
- Molecular Mechanisms of Chemoprevention: NRF2 SignalingThomas W Kensler; Fiscal Year: 2010..of isotope-dilution mass spectrometry for the quantitation of aflatoxin biomarkers in liver, blood, urine and feces in order to develop for the first time a comprehensive mass balance for the fate of the ultimate carcinogen, exo-..
- Necrotizing Enterocolitis: Prevention and PredictionMark Underwood; Fiscal Year: 2009..a series of in vitro experiments to (a) analyze biochemical and genetic properties of the bifidobacteria in the feces of infants receiving prebiotic oligosaccharides and/or probiotic microbes and (b) analyze the prebiotic properties ..
- Necrotizing Enterocolitis: Prevention and PredictionMARK ALAN contact UNDERWOOD; Fiscal Year: 2010..a series of in vitro experiments to (a) analyze biochemical and genetic properties of the bifidobacteria in the feces of infants receiving prebiotic oligosaccharides and/or probiotic microbes and (b) analyze the prebiotic properties ..
- Necrotizing Enterocolitis: Prevention and PredictionMark Underwood; Fiscal Year: 2009..a series of in vitro experiments to (a) analyze biochemical and genetic properties of the bifidobacteria in the feces of infants receiving prebiotic oligosaccharides and/or probiotic microbes and (b) analyze the prebiotic properties ..
- Cholesterol Ester Hydrolysis and Cholesterol EffluxShobha Ghosh; Fiscal Year: 2009..enhanced the flux of cholesterol from macrophages to liver for the final elimination as bile acids into bile and feces providing direct evidence that enhanced CEH-mediated intracellular CE hydrolysis is anti-atherogenic...
- Quantitation of Tocopherol Metabolism in HumansAndrew Clifford; Fiscal Year: 2009..Erythrocytes, lymphocytes, and platelets will also be separated. Urine and feces will be collected until 30 days post dose...
- Cholesterol Ester Hydrolysis and Cholesterol EffluxShobha Ghosh; Fiscal Year: 2010..enhanced the flux of cholesterol from macrophages to liver for the final elimination as bile acids into bile and feces providing direct evidence that enhanced CEH-mediated intracellular CE hydrolysis is anti-atherogenic...
- Quantitation of Tocopherol Metabolism in HumansANDREW JOSEPH CLIFFORD; Fiscal Year: 2010..Erythrocytes, lymphocytes, and platelets will also be separated. Urine and feces will be collected until 30 days post dose...
- Parasite/Host Interactions and the Neurobiology of FearRobert Sapolsky; Fiscal Year: 2006..The parasite reproduces in cats, and is then excreted. Infected feces are eaten by rodents, in which Toxoplasma forms cysts in muscle and the CNS...
- CLINICAL EXPERIMENT OF HELICOBACTER PYLORI TRANSMISSIONJulie Parsonnet; Fiscal Year: 1999..pylori organisms are present in vomitus, air samples obtained during vomiting, saliva and/or feces. To do this, we intend to conduct a clinical experiment in 30 H. pylori infected volunteers...
- PMCA Detection of CWD Infection in Cervid and Non-Cervid SpeciesEDWARD ARTHUR HOOVER; Fiscal Year: 2010..serial protein misfolding cyclic amplification (sPMCA) to amplify and detect PrPCWD in saliva, blood, urine, and feces of infected deer...
- IMMUNITY AND PATHOGENESIS OF A NOVEL NOROVIRUSHerbert W Virgin; Fiscal Year: 2010..Interestingly, certain MNV strains persistently replicate in intestine of WT mice and are shed in feces for weeks despite a significant immune response...
- IMMUNITY AND PATHOGENESIS OF A NOVEL NOROVIRUSHerbert W Virgin; Fiscal Year: 2010..Interestingly, certain MNV strains persistently replicate in intestine of WT mice and are shed in feces for weeks despite a significant immune response...
- FACILITY RENOVATION AND ANNENBERG CAGE WASH FACILITIYKenneth Davis; Fiscal Year: 2003..has recurrent leaks onto the lower research floors, exposing personnel to hazardous waste water (primate and swine feces) from the unit and associated plumbing...
- REGULATION OF ENTERIC HYPEROXALURI BY OXALOBACTERAMMON PECK; Fiscal Year: 2001..per gram feces and the frequency of recurrent urolithiasis, inflammatory bowel disease and hyperoxaluria/nephrocalcinosis in ..
- IMPROVING VIRTUAL COLONOSCOPY WITH COMPUTER DETECTIONPeter Santago; Fiscal Year: 2001..To optimize bowel preparation with digital subtraction of opacified feces and controlled gas distention; and 4...
- NOVEL E. COLI 0157:H7 INTESTINAL COLONIZATION FACTORSJAMES KAPER; Fiscal Year: 2009..Infection begins by ingestion of food or water that is contaminated with EHEC, often from contact with cattle feces, the primary reservoir of the organism. The extremely infectious dose required for disease, ca...
- Impact of Fiber Fermentation on Fecal IncontinenceDonna Bliss; Fiscal Year: 2007Fecal incontinence (FI), the involuntary leakage of feces, is a chronic problem with debilitating effects on health and well-being...
- NOVEL E. COLI 0157:H7 INTESTINAL COLONIZATION FACTORSJAMES KAPER; Fiscal Year: 2007..Infection begins by ingestion of food or water that is contaminated with EHEC, often from contact with cattle feces, the primary reservoir of the organism. The extremely infectious dose required for disease, ca...
