feces

Summary

Summary: Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.

Top Publications

  1. pmc A human gut microbial gene catalogue established by metagenomic sequencing
    Junjie Qin
    BGI Shenzhen, Shenzhen 518083, China
    Nature 464:59-65. 2010
  2. pmc A core gut microbiome in obese and lean twins
    Peter J Turnbaugh
    Center for Genome Sciences, Washington University School of Medicine, St Louis, Missouri 63108, USA
    Nature 457:480-4. 2009
  3. pmc Diversity of the human intestinal microbial flora
    Paul B Eckburg
    Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Room S 169, 300 Pasteur Drive, Stanford CA 94305 5107, USA
    Science 308:1635-8. 2005
  4. pmc Evolution of mammals and their gut microbes
    Ruth E Ley
    Center for Genome Sciences, Washington University School of Medicine, St Louis, MO 63108, USA
    Science 320:1647-51. 2008
  5. pmc Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
    Carlotta De Filippo
    Department of Preclinical and Clinical Pharmacology, University of Florence, 50139 Firenze, Italy
    Proc Natl Acad Sci U S A 107:14691-6. 2010
  6. pmc The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing
    Les Dethlefsen
    Department of Microbiology and Immunology, Stanford University, Stanford, California, United States of America
    PLoS Biol 6:e280. 2008
  7. pmc Succession of microbial consortia in the developing infant gut microbiome
    Jeremy E Koenig
    Department of Microbiology, Cornell University, Ithaca, NY 14853, USA
    Proc Natl Acad Sci U S A 108:4578-85. 2011
  8. pmc Metagenomic analysis of the human distal gut microbiome
    Steven R Gill
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 312:1355-9. 2006
  9. pmc Development of the human infant intestinal microbiota
    Chana Palmer
    Department of Genetics, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS Biol 5:e177. 2007
  10. doi Microbiota and SCFA in lean and overweight healthy subjects
    Andreas Schwiertz
    Institute of Microecology, Auf den Lüppen 8, Herborn, Germany
    Obesity (Silver Spring) 18:190-5. 2010

Detail Information

Publications234 found, 100 shown here

  1. pmc A human gut microbial gene catalogue established by metagenomic sequencing
    Junjie Qin
    BGI Shenzhen, Shenzhen 518083, China
    Nature 464:59-65. 2010
    ..We define and describe the minimal gut metagenome and the minimal gut bacterial genome in terms of functions present in all individuals and most bacteria, respectively...
  2. pmc A core gut microbiome in obese and lean twins
    Peter J Turnbaugh
    Center for Genome Sciences, Washington University School of Medicine, St Louis, Missouri 63108, USA
    Nature 457:480-4. 2009
    ....
  3. pmc Diversity of the human intestinal microbial flora
    Paul B Eckburg
    Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Room S 169, 300 Pasteur Drive, Stanford CA 94305 5107, USA
    Science 308:1635-8. 2005
    ..We examined 13,355 prokaryotic ribosomal RNA gene sequences from multiple colonic mucosal sites and feces of healthy subjects to improve our understanding of gut microbial diversity...
  4. pmc Evolution of mammals and their gut microbes
    Ruth E Ley
    Center for Genome Sciences, Washington University School of Medicine, St Louis, MO 63108, USA
    Science 320:1647-51. 2008
    ....
  5. pmc Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
    Carlotta De Filippo
    Department of Preclinical and Clinical Pharmacology, University of Florence, 50139 Firenze, Italy
    Proc Natl Acad Sci U S A 107:14691-6. 2010
    ....
  6. pmc The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing
    Les Dethlefsen
    Department of Microbiology and Immunology, Stanford University, Stanford, California, United States of America
    PLoS Biol 6:e280. 2008
    ..The rapid return to the pretreatment community composition is indicative of factors promoting community resilience, the nature of which deserves future investigation...
  7. pmc Succession of microbial consortia in the developing infant gut microbiome
    Jeremy E Koenig
    Department of Microbiology, Cornell University, Ithaca, NY 14853, USA
    Proc Natl Acad Sci U S A 108:4578-85. 2011
    ..This study revealed that seemingly chaotic shifts in the microbiome are associated with life events; however, additional experiments ought to be conducted to assess how different infants respond to similar life events...
  8. pmc Metagenomic analysis of the human distal gut microbiome
    Steven R Gill
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 312:1355-9. 2006
    ..Thus, humans are superorganisms whose metabolism represents an amalgamation of microbial and human attributes...
  9. pmc Development of the human infant intestinal microbiota
    Chana Palmer
    Department of Genetics, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS Biol 5:e177. 2007
    ..By the end of the first year of life, the idiosyncratic microbial ecosystems in each baby, although still distinct, had converged toward a profile characteristic of the adult gastrointestinal tract...
  10. doi Microbiota and SCFA in lean and overweight healthy subjects
    Andreas Schwiertz
    Institute of Microecology, Auf den Lüppen 8, Herborn, Germany
    Obesity (Silver Spring) 18:190-5. 2010
    ..However, our results contradict previous reports with regard to the contribution of various bacterial groups to the development of obesity and this issue remains controversial...
  11. pmc Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation
    Les Dethlefsen
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 108:4554-61. 2011
    ..Antibiotic perturbation may cause a shift to an alternative stable state, the full consequences of which remain unknown...
  12. pmc Gut microbiota in human adults with type 2 diabetes differs from non-diabetic adults
    Nadja Larsen
    Department of Food Science, University of Copenhagen, Frederiksberg, Denmark
    PLoS ONE 5:e9085. 2010
    ..The aim of this study was to assess the differences between the composition of the intestinal microbiota in humans with type 2 diabetes and non-diabetic persons as control...
  13. ncbi Factors influencing the composition of the intestinal microbiota in early infancy
    John Penders
    Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, PO Box 616, 6200 MD Maastricht, Netherlands
    Pediatrics 118:511-21. 2006
    ..The aim of this study was to examine the contribution of a broad range of external influences to the gut microbiotic composition in early infancy...
  14. pmc Accuracy of urine circulating cathodic antigen (CCA) test for Schistosoma mansoni diagnosis in different settings of Côte d'Ivoire
    Jean T Coulibaly
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 5:e1384. 2011
    ..We assessed the accuracy of a commercially available CCA cassette test (designated CCA-A) and an experimental formulation (CCA-B) for S. mansoni diagnosis...
  15. pmc Composition, variability, and temporal stability of the intestinal microbiota of the elderly
    Marcus J Claesson
    Department of Microbiology, University College, Cork, Ireland
    Proc Natl Acad Sci U S A 108:4586-91. 2011
    ..We conclude that the fecal microbiota of the elderly shows temporal stability over limited time in the majority of subjects but is characterized by unusual phylum proportions and extreme variability...
  16. ncbi Towards the human intestinal microbiota phylogenetic core
    Julien Tap
    INRA, UEPSD, UR910, 78350 Jouy en Josas, France
    Environ Microbiol 11:2574-84. 2009
    ..Its role in human health deserves further study...
  17. doi Fidaxomicin versus vancomycin for Clostridium difficile infection
    Thomas J Louie
    University of Calgary, Calgary, AB, Canada
    N Engl J Med 364:422-31. 2011
    ..This phase 3 clinical trial compared the efficacy and safety of fidaxomicin with those of vancomycin in treating C. difficile infection...
  18. pmc Organismal, genetic, and transcriptional variation in the deeply sequenced gut microbiomes of identical twins
    Peter J Turnbaugh
    Center for Genome Sciences, Washington University School of Medicine, St Louis, MO 63108, USA
    Proc Natl Acad Sci U S A 107:7503-8. 2010
    ..g., predicted cellulases, dockerins), and transcriptional activities. These results provide an expanded perspective about features that make each of us unique life forms and directions for future characterization of our gut ecosystems...
  19. pmc Diagnosis of soil-transmitted helminths in the era of preventive chemotherapy: effect of multiple stool sampling and use of different diagnostic techniques
    Stefanie Knopp
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    PLoS Negl Trop Dis 2:e331. 2008
    ..In this study, we focused on schoolchildren on Unguja Island, Zanzibar, an area where anthelminthic drugs have been repeatedly administered over the past decade...
  20. pmc Comparing diagnostic accuracy of Kato-Katz, Koga agar plate, ether-concentration, and FLOTAC for Schistosoma mansoni and soil-transmitted helminths
    Dominik Glinz
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 4:e754. 2010
    ..Accurate diagnosis is crucial for patient management, drug efficacy evaluations, and monitoring of large-scale community-based control programs...
  21. doi A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes
    Ben P Willing
    Department of Microbiology, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Gastroenterology 139:1844-1854.e1. 2010
    ..Interindividual variation and an inability to detect less abundant bacteria have made it difficult to correlate specific bacteria with disease...
  22. pmc Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients
    Fabrice Armougom
    URMITE UMR CNRS 6236, IRD 3R198, Universite de la Mediterranee, Faculte de Medecine, and Nutrition and Diabetology Department, University Hospital Sainte Marguerite, Marseille, France
    PLoS ONE 4:e7125. 2009
    ..Determining the variations of microbial communities in feces may be beneficial for the identification of specific profiles in patients with abnormal weights...
  23. pmc Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians
    Elena Biagi
    Department of Pharmaceutical Sciences, University of Bologna, Bologna, Italy
    PLoS ONE 5:e10667. 2010
    ....
  24. doi Comparative analysis of fecal DNA extraction methods with phylogenetic microarray: effective recovery of bacterial and archaeal DNA using mechanical cell lysis
    Anne Salonen
    Department of Basic Veterinary Sciences, Division of Microbiology and Epidemiology, University of Helsinki, P O Box 66, FI 00014, Helsinki, Finland
    J Microbiol Methods 81:127-34. 2010
    ..The assessment of performance differences between different methodologies serves as a concrete step towards the comparison and reliable meta-analysis of the results obtained in different laboratories...
  25. pmc Comparative fecal metagenomics unveils unique functional capacity of the swine gut
    Regina Lamendella
    National Risk Management Research Laboratory, U S Environmental Protection Agency, Cincinnati, OH 45268, USA
    BMC Microbiol 11:103. 2011
    ..importance to animal physiology and health as well as to food and water safety due to the presence of human pathogens in pig feces. Nonetheless, limited information on the functional diversity of the swine gut microbiome is available.
  26. doi Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome
    Mirjana Rajilić-Stojanović
    Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands
    Gastroenterology 141:1792-801. 2011
    ..We aimed to define microbial populations that can be used discriminate the fecal microbiota of patients with IBS from that of healthy subjects and correlate these with IBS intestinal symptom scores...
  27. pmc Development and application of the human intestinal tract chip, a phylogenetic microarray: analysis of universally conserved phylotypes in the abundant microbiota of young and elderly adults
    Mirjana Rajilić-Stojanović
    Laboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, The Netherlands
    Environ Microbiol 11:1736-51. 2009
    ....
  28. doi Low counts of Faecalibacterium prausnitzii in colitis microbiota
    H Sokol
    UEPSD, INRA, Jouy en Josas, France
    Inflamm Bowel Dis 15:1183-9. 2009
    ..The aim was to compare the fecal microbiota composition of patients with colitis to that of healthy subjects (HS)...
  29. doi Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives
    Marie Joossens
    Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium
    Gut 60:631-7. 2011
    ..Whether dysbiosis is present in relatives of patients CD was also examined...
  30. pmc Evaluation of the bacterial diversity in the feces of cattle using 16S rDNA bacterial tag-encoded FLX amplicon pyrosequencing (bTEFAP)
    Scot E Dowd
    USDA ARS Livestock Issues Research Unit, Lubbock, TX 79403, USA
    BMC Microbiol 8:125. 2008
    ..We have evaluated the microbiome from the feces of 20 commercial, lactating dairy cows.
  31. pmc Diagnosis, clinical features, and self-reported morbidity of Strongyloides stercoralis and hookworm infection in a Co-endemic setting
    Sören L Becker
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 5:e1292. 2011
    ..Moreover, clinical data on symptomatology and typical recognition patterns mainly originate from Western travel clinics...
  32. ncbi Escherichia coli harboring Shiga toxin 2 gene variants: frequency and association with clinical symptoms
    Alexander W Friedrich
    Institut fur Hygiene und Mikrobiologie der Universitat Wurzburg, Wurzburg, Germany
    J Infect Dis 185:74-84. 2002
    ..stx2c-positive STEC isolates can cause HUS, but the presence of stx2d or stx2e may predict a milder disease with a minimal risk of HUS...
  33. ncbi Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosis
    Qing Liu
    Artificial Liver Treatment and Training Center, Beijing Youan Hospital and Capital University of Medical Sciences, Beijing, China
    Hepatology 39:1441-9. 2004
    ..In conclusion, treatment with synbiotics or fermentable fiber is an alternative to lactulose for the management of MHE in patients with cirrhosis...
  34. pmc Characterization of the fecal microbiome from non-human wild primates reveals species specific microbial communities
    Suleyman Yildirim
    The Institute for Genomic Biology, University of Illinois, Urbana, Illinois, United States of America
    PLoS ONE 5:e13963. 2010
    ..Here we present a comparative analysis of gastrointestinal microbial communities from three different species of Old World wild monkeys...
  35. pmc Assessment of the anthelmintic efficacy of albendazole in school children in seven countries where soil-transmitted helminths are endemic
    Jozef Vercruysse
    Department of Virology, Parasitology and Immunology, Ghent University, Faculty of Veterinary Medicine, Merelbeke, Belgium
    PLoS Negl Trop Dis 5:e948. 2011
    ..The objective of this study, therefore, was to define the efficacy of a single 400 milligram dose of albendazole (ALB) against these three STH using a standardized protocol...
  36. ncbi Long-term ecological impacts of antibiotic administration on the human intestinal microbiota
    Cecilia Jernberg
    Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden
    ISME J 1:56-66. 2007
    ....
  37. ncbi Stool form scale as a useful guide to intestinal transit time
    S J Lewis
    University Dept of Medicine, Bristol Royal Infirmary, UK
    Scand J Gastroenterol 32:920-4. 1997
    ..We set out to assess the responsiveness of the Bristol stool form scale to change in transit time...
  38. pmc Metagenomic analyses of viruses in stool samples from children with acute flaccid paralysis
    Joseph G Victoria
    Blood Systems Research Institute, San Francisco, California 94118, USA
    J Virol 83:4642-51. 2009
    ....
  39. pmc Fecal microbiota in premature infants prior to necrotizing enterocolitis
    Volker Mai
    Department of Microbiology and Cell Sciences and Emerging Pathogens Institute, University of Florida, Gainesville, Florida, United States of America
    PLoS ONE 6:e20647. 2011
    ..Our observations suggest that abnormal patterns of microbiota and potentially a novel pathogen contribute to the etiology of NEC...
  40. doi Human colonic microbiota associated with diet, obesity and weight loss
    S H Duncan
    Rowett Institute of Nutrition and Health, University of Aberdeen, Bucksburn, Aberdeen, UK
    Int J Obes (Lond) 32:1720-4. 2008
    ..It has been proposed that the development of obesity in humans is influenced by the relative proportions of the two major phyla of bacteria (Bacteroidetes and Firmicutes) present in the large intestine...
  41. pmc Evaluation of urine CCA assays for detection of Schistosoma mansoni infection in Western Kenya
    Hillary L Shane
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS Negl Trop Dis 5:e951. 2011
    ..Our results suggest that urine-based assays for CCA may be valuable in screening for S. mansoni infections...
  42. ncbi Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR
    Erja Malinen
    Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine, Section of Microbiology, P O Box 66, FIN 00014 University of Helsinki, Finland
    Am J Gastroenterol 100:373-82. 2005
    ..The gut microbiota may contribute to the onset and maintenance of irritable bowel syndrome (IBS). In this study, the microbiotas of patients suffering from IBS were compared with a control group devoid of gastrointestinal (GI) symptoms...
  43. ncbi Development of an extensive set of 16S rDNA-targeted primers for quantification of pathogenic and indigenous bacteria in faecal samples by real-time PCR
    T Rinttilä
    Section of Microbiology, Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine, Helsinki University, Helsinki, Finland
    J Appl Microbiol 97:1166-77. 2004
    ..We report the design and optimization of an extensive set of 16S rDNA-targeted species- and group-specific primers for more accurate quantification of bacteria from faecal samples with real-time PCR...
  44. ncbi Molecular characterisation of the faecal microbiota in patients with type II diabetes
    Xiaokang Wu
    Department of Immunology and Pathogenic Biology, Molecular Bacteriology Laboratory, Key Laboratory of Environment and Genes Related to Diseases of Chinese Ministry of Education, School of Medicine, Xi an Jiaotong University, 710061, Xi an, Shaanxi Province, People s Republic of China
    Curr Microbiol 61:69-78. 2010
    ..Taken together, in this work we observed the characterisation of gut microbiota in diabetic patients, which suggests that the gut microbiota of diabetes patients have some changes associated with occurrence and development of diabetes...
  45. doi Development of a real-time PCR method for Firmicutes and Bacteroidetes in faeces and its application to quantify intestinal population of obese and lean pigs
    X Guo
    Institute of Animal Nutrition, Sichuan Agricultural University, Yaan, Sichuan, China
    Lett Appl Microbiol 47:367-73. 2008
    ..To investigate whether the relative abundance of the Bacteroidetes and Firmicutes divisions in pigs is different between obese and lean animals...
  46. ncbi Early differences in fecal microbiota composition in children may predict overweight
    Marko Kalliomaki
    Functional Foods Forum and Program on Health Biosciences and the Department of Pediatrics, University of Turku, Turku, Finland
    Am J Clin Nutr 87:534-8. 2008
    ..Experimental studies suggest that gut microbiota deviations predispose toward energy storage and obesity...
  47. pmc Fecal MicroRNAs as novel biomarkers for colon cancer screening
    Alexander Link
    Gastrointestinal Cancer Research Laboratory, Baylor University Medical Center, Dallas, TX 75246, USA
    Cancer Epidemiol Biomarkers Prev 19:1766-74. 2010
    ..MicroRNAs (miRNA) play an important role in a wide array of biological processes and are commonly dysregulated in neoplasia. We aimed to evaluate the feasibility of fecal miRNAs as biomarkers for colorectal neoplasia screening...
  48. pmc Molecular identification of extended-spectrum-β-lactamase genes from Enterobacteriaceae isolated from healthy human carriers in Switzerland
    Nadine Geser
    Vetsuisse Faculty, Institute for Food Safety and Hygiene, University of Zurich, Zurich, Switzerland
    Antimicrob Agents Chemother 56:1609-12. 2012
    ..One strain produced SHV-12 ESBL. Of the 34 isolates, 15 produced additional TEM-1 broad-spectrum β-lactamases. By serotyping, a high degree of diversity among the strains was found...
  49. doi Shotgun metaproteomics of the human distal gut microbiota
    Nathan C Verberkmoes
    Oak Ridge National Laboratory, Chemical and Life Sciences Divisions, Oak Ridge, TN, USA
    ISME J 3:179-89. 2009
    ..Several unknown proteins represented previously undescribed microbial pathways or host immune responses, revealing a novel complex interplay between the human host and its associated microbes...
  50. pmc Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using real-time PCR and effects of antibiotic treatment on the fecal microbiota
    Sabine Bartosch
    MRC Microbiology and Gut Biology Group, University of Dundee, Dundee, United Kingdom
    Appl Environ Microbiol 70:3575-81. 2004
    ..primer sets targeting 16S rRNA genes were used to quantitate intestinal bacteria by using DNA extracted from feces and real-time PCR...
  51. pmc Human bocaviruses are highly diverse, dispersed, recombination prone, and prevalent in enteric infections
    Amit Kapoor
    Blood Systems Research Institute, and Department of Laboratory Medicine, University of California San Francisco, 270 Masonic Ave, San Francisco, CA 94118, USA
    J Infect Dis 201:1633-43. 2010
    A new species of parvovirus, tentatively named human bocavirus 4 (HBoV4), was genetically characterized. Among 641 feces samples obtained from children and adults, the most commonly detected bocavirus species were, in descending order, ..
  52. pmc Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from feces
    Erwin G Zoetendal
    Wageningen Centre for Food Sciences, Laboratory of Microbiology, Hesselink van Suchtelenweg 4, 6703 CT Wageningen, The Netherlands
    Appl Environ Microbiol 68:3401-7. 2002
    The human gastrointestinal (GI) tract harbors a complex community of bacterial cells in the mucosa, lumen, and feces. Since most attention has been focused on bacteria present in feces, knowledge about the mucosa-associated bacterial ..
  53. doi A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficile-infected patients than does vancomycin
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Microbiology 156:3354-9. 2010
    ..These findings help to explain the substantially reduced rates of relapse following treatment of CDI with fidaxomicin in recent clinical trials...
  54. pmc Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cell Host Microbe 8:292-300. 2010
    ..Cross-fostering experiments indicated a role for these organisms in maternal transmission of disease. Our findings illustrate how gut microbial communities work in concert with specific culturable colitogenic agents to cause IBD...
  55. pmc Community structures of fecal bacteria in cattle from different animal feeding operations
    Orin C Shanks
    U S Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, 26 West Martin Luther King Dr, Cincinnati, OH 45268, USA
    Appl Environ Microbiol 77:2992-3001. 2011
    ....
  56. doi Commensal Escherichia coli of healthy humans: a reservoir for antibiotic-resistance determinants
    Jannine K Bailey
    School of Molecular Bioscience, The University of Sydney, NSW 2006, Australia
    J Med Microbiol 59:1331-9. 2010
    ..coli of healthy humans represent an important reservoir for numerous antibiotic-resistance genes in many combinations. However, measuring the true extent of resistance carriage in commensal E. coli requires in-depth analysis...
  57. ncbi The influence of sampling effort and the performance of the Kato-Katz technique in diagnosing Schistosoma mansoni and hookworm co-infections in rural Côte d'Ivoire
    M Booth
    Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    Parasitology 127:525-31. 2003
    ..If confirmed in other settings, these findings have implications for estimating the prevalence of multiple species helminth infections, and hence the design and implementation of efficacious and cost-effective control programmes...
  58. pmc A pentaplex real-time polymerase chain reaction assay for detection of four species of soil-transmitted helminths
    Madihah Basuni
    Institute for Research in Molecular Medicine, Universiti Sains Malaysia USM, Penang, Malaysia
    Am J Trop Med Hyg 84:338-43. 2011
    ..05). In conclusion, the real-time PCR assay described in this study provides a specific and sensitive diagnostic tool for the detection of these four helminth species in epidemiological studies and monitoring of treatment programs...
  59. ncbi Relative contribution of day-to-day and intra-specimen variation in faecal egg counts of Schistosoma mansoni before and after treatment with praziquantel
    J Utzinger
    Swiss Tropical Institute, Basel
    Parasitology 122:537-44. 2001
    ..We conclude that diagnostic sensitivity in high transmission areas is maximized by making several stool readings on several days, but examining 1 stool specimen several times can make reasonable estimates of infection intensity...
  60. doi Gastrointestinal microbiota in irritable bowel syndrome: present state and perspectives
    Anne Salonen
    Department of Veterinary Biosciences, Veterinary Microbiology and Epidemiology, University of Helsinki, PO Box 66, FI 00014 Helsinki, Finland
    Microbiology 156:3205-15. 2010
    ..Finally, we discuss the future outlook for research avenues and candidate microbial biomarkers that may eventually be used in IBS diagnosis...
  61. doi FLOTAC: new multivalent techniques for qualitative and quantitative copromicroscopic diagnosis of parasites in animals and humans
    Giuseppe Cringoli
    Department of Pathology and Animal Health, Faculty of Veterinary Medicine, University of Naples Federico II, CREMOPAR Regione Campania, Naples, Italy
    Nat Protoc 5:503-15. 2010
    ..All FLOTAC techniques can be performed on fresh fecal material as well as preserved stool samples, and require approximately 12-15 min of preparation time before microscopic analysis...
  62. ncbi The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects
    Anna Kassinen
    Department of Basic Veterinary Sciences, Division of Microbiology and Epidemiology, University of Helsinki, Helsinki, Finland
    Gastroenterology 133:24-33. 2007
    ..Our objective was to characterize putative differences in gastrointestinal microbiota between patients with IBS and control subjects. These differences could potentially have a causal relationship with the syndrome...
  63. pmc Prevalence of Campylobacter, Arcobacter, Helicobacter, and Sutterella spp. in human fecal samples as estimated by a reevaluation of isolation methods for Campylobacters
    J Engberg
    Department of Gastrointestinal Infections, Division of Diagnostics, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
    J Clin Microbiol 38:286-91. 2000
    ..This paper provides evidence for the existence of S. wadsworthensis in human feces from clinical cases of gastrointestinal disorders and in feces from a healthy individual. Furthermore, C...
  64. ncbi Improved extraction of PCR-quality community DNA from digesta and fecal samples
    Zhongtang Yu
    Dept of Animal Sciences, Ohio State University, 2027 Coffey Road, OH 43210, USA
    Biotechniques 36:808-12. 2004
    ....
  65. doi Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome
    C Tana
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
    Neurogastroenterol Motil 22:512-9, e114-5. 2010
    ..We hypothesized in this study that altered GI microbiota contribute to IBS symptoms through increased levels of organic acids...
  66. ncbi Albendazole and mebendazole administered alone or in combination with ivermectin against Trichuris trichiura: a randomized controlled trial
    Stefanie Knopp
    Departments of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Clin Infect Dis 51:1420-8. 2010
    ..Single-dose albendazole and mebendazole show limited efficacy in the treatment of trichuriasis. The combination of albendazole with ivermectin improves efficacy, but a mebendazole-ivermectin combination has not been previously investigated...
  67. doi Characterization of the fecal bacteria communities of forage-fed horses by pyrosequencing of 16S rRNA V4 gene amplicons
    Megan L Shepherd
    Large Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Blacksburg, VA 24061, USA
    FEMS Microbiol Lett 326:62-8. 2012
    ..fecal bacterial richness was higher than that reported in humans, but lower than that reported in either cattle feces or soil. Bacterial classified sequences were assigned to 16 phyla, of which 10 were present in all samples...
  68. ncbi Dysbiosis of fecal microbiota in Crohn's disease patients as revealed by a custom phylogenetic microarray
    Seungha Kang
    Preventative Health National Research Flagship, CSIRO, St Lucia, QLD, Australia
    Inflamm Bowel Dis 16:2034-42. 2010
    ....
  69. pmc 16S rRNA gene-based analysis of fecal microbiota from preterm infants with and without necrotizing enterocolitis
    Yunwei Wang
    Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    ISME J 3:944-54. 2009
    ..Our results suggest that NEC is associated with severe lack of microbiota diversity that may accentuate the impact of single dominant microorganisms favored by empiric and widespread use of antibiotics...
  70. pmc Gut microbiota composition and development of atopic manifestations in infancy: the KOALA Birth Cohort Study
    John Penders
    Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Gut 56:661-7. 2007
    ..We examined gut microbiota composition in early infancy and the subsequent development of atopic manifestations and sensitisation...
  71. ncbi Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles
    Liam O'Mahony
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Gastroenterology 128:541-51. 2005
    ..The aim of this study was to compare the response of symptoms and cytokine ratios in irritable bowel syndrome (IBS) with ingestion of probiotic preparations containing a lactobacillus or bifidobacterium strain...
  72. pmc Molecular monitoring of succession of bacterial communities in human neonates
    Christine F Favier
    Laboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University, 6703 CT Wageningen, The Netherlands
    Appl Environ Microbiol 68:219-26. 2002
    ..Clone libraries of amplified 16S rDNA fragments from baby feces were constructed, and these libraries allowed identification of the bacterial types by comparative DNA sequence ..
  73. ncbi The burden of polyparasitism among primary schoolchildren in rural and farming areas in Zimbabwe
    N Midzi
    National Institute of Health Research, Box CY 573, Causeway, Harare, Zimbabwe
    Trans R Soc Trop Med Hyg 102:1039-45. 2008
    ....
  74. pmc Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers
    Lotta Krogius-Kurikka
    Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine, PO Box 66, FI 00014 University of Helsinki, Helsinki, Finland
    BMC Gastroenterol 9:95. 2009
    ..The method allowed microbial community analysis on all levels of microbial genomic guanine plus cytosine (G+C) content, including high G+C bacteria...
  75. pmc Estimating the sensitivity and specificity of Kato-Katz stool examination technique for detection of hookworms, Ascaris lumbricoides and Trichuris trichiura infections in humans in the absence of a 'gold standard'
    M R Tarafder
    Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Parasitol 40:399-404. 2010
    ..lumbricoides and T. trichiura. Low sensitivity of the Kato-Katz for detection of hookworm infection may be related to rapid degeneration of delicate hookworm eggs with time...
  76. ncbi Early intestinal bacterial colonization and necrotizing enterocolitis in premature infants: the putative role of Clostridium
    Marie France de la Cochetiere
    INSERM Unité 539, CHU Hotel Dieu, 44035 Nantes cedex 1, France
    Pediatr Res 56:366-70. 2004
    ....
  77. pmc Real-time PCR quantitation of clostridia in feces of autistic children
    Yuli Song
    Research Service, VA Medical Center West Los Angeles, Los Angeles, California 90073, USA
    Appl Environ Microbiol 70:6459-65. 2004
    ..8 x 10(8) CFU/g in controls; respectively). More subjects need to be studied. The assay is a rapid and reliable method, and it should have great potential for quantitation of other bacteria in the intestinal tract...
  78. pmc A novel bocavirus associated with acute gastroenteritis in Australian children
    Jane L Arthur
    Infectious Diseases Laboratories, Institute of Medical and Veterinary Science, Adelaide, Australia
    PLoS Pathog 5:e1000391. 2009
    ..7%), and it was not associated with AGE. HBoV2 and HBoV3 are newly discovered bocaviruses, of which HBoV2 is the thirdmost-prevalent virus, after rotavirus and astrovirus, associated with pediatric AGE in this study...
  79. ncbi The microbiology of butyrate formation in the human colon
    Susan E Pryde
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    FEMS Microbiol Lett 217:133-9. 2002
    ....
  80. pmc Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic
    Rubhana Raqib
    International Centre for Diarrhoeal Disease Research Bangladesh, Centre for Health and Population Research, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 103:9178-83. 2006
    ....
  81. pmc Chimpanzee reservoirs of pandemic and nonpandemic HIV-1
    Brandon F Keele
    Departments of Medicine and Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA
    Science 313:523-6. 2006
    ..These findings establish P. t. troglodytes as a natural reservoir of HIV-1...
  82. pmc Diet-induced metabolic improvements in a hamster model of hypercholesterolemia are strongly linked to alterations of the gut microbiota
    Inés Martínez
    Department of Food Science and Technology, University of Nebraska, Lincoln, 68583 0919, USA
    Appl Environ Microbiol 75:4175-84. 2009
    ..This study provides evidence that modulation of the gut microbiota-host metabolic interrelationship by dietary intervention has the potential to improve mammalian cholesterol homeostasis, which has relevance for cardiovascular health...
  83. pmc The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age
    D Mariat
    INRA, U910, Unité d Ecologie et du Système Digestif, Domaine de Vilvert, 78350 Jouy en Josas, France
    BMC Microbiol 9:123. 2009
    ..Applying current molecular methods is necessary to surmount the limitations of classical culturing techniques in order to obtain an accurate description of the microbiota composition...
  84. pmc A newly identified bocavirus species in human stool
    Amit Kapoor
    Blood Systems Research Institute and Department of Laboratory Medicine, University of California, San Francisco, CA 94118, USA
    J Infect Dis 199:196-200. 2009
    ..Further studies are necessary to identify anatomical sites of HBoV2 replication and potential associations with clinical symptoms or disease...
  85. ncbi Clinical and molecular epidemiology of human bocavirus in respiratory and fecal samples from children in Hong Kong
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, University of Hong Kong, Hong Kong, China
    J Infect Dis 196:986-93. 2007
    ..We conducted the first systematic prospective clinical and molecular study using nasopharyngeal aspirates (NPAs) and fecal samples...
  86. doi Combined PCR-DGGE fingerprinting and quantitative-PCR indicates shifts in fecal population sizes and diversity of Bacteroides, bifidobacteria and Clostridium cluster IV in institutionalized elderly
    Jutta Zwielehner
    Department of Nutritional Sciences, University of Vienna, Austria
    Exp Gerontol 44:440-6. 2009
    ..This study aimed at determining ageing-related shifts in diversity and composition of key members of the fecal microbiota by comparing institutionalized elderly (n = 17, 78-94 years) and young volunteers (n = 17, 18-31 years)...
  87. ncbi The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Cote d'Ivoire
    Michael B Zimmermann
    Institute of Food, Nutrition and Health, Swiss Federal Institute of Technology Zurich, Zurich, Switzerland
    Am J Clin Nutr 92:1406-15. 2010
    ..Thus, increasing colonic iron could select gut microbiota for humans that are unfavorable to the host...
  88. doi Longitudinal investigation of the faecal microbiota of healthy full-term infants using fluorescence in situ hybridization and denaturing gradient gel electrophoresis
    Laure C Roger
    Microbial Ecology and Health Group, Food Microbial Sciences Unit, Department of Food and Nutritional Sciences, University of Reading, Whiteknights Campus, PO Box 226, Reading RG6 6AP, UK
    Microbiology 156:3317-28. 2010
    ..These data can be of help to future clinical trials (e.g. targeted weaning products) to organize protocols and obtain a more accurate outline of the changes and dynamics of the infant GI microbiota...
  89. pmc Intestinal schistosomiasis in mothers and young children in Uganda: investigation of field-applicable markers of bowel morbidity
    Martha Betson
    Wolfson Wellcome Biomedical Laboratories, Department of Zoology, Natural History Museum, London, United Kingdom
    Am J Trop Med Hyg 83:1048-55. 2010
    ..0001) and mothers (n = 448, OR = 1.95, P = 0.004). Fecal occult blood appears to be useful for measuring morbidity associated with intestinal schistosomiasis and could be used in assessing the impact of control programs upon disease...
  90. doi Influence of early gut microbiota on the maturation of childhood mucosal and systemic immune responses
    Y M Sjögren
    Department of Immunology, Wenner Gren Institute, Stockholm University, Stockholm, Sweden
    Clin Exp Allergy 39:1842-51. 2009
    ..Although animal and in vitro studies emphasize the role of the commensal gut microbiota in the development of the immune system, the influence of the gut microbiota on immune development in infants is unclear...
  91. pmc Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice
    Andrew L Goodman
    Center for Genome Science and Systems Biology, Washington University School of Medicine, St Louis, MO 63108, USA
    Proc Natl Acad Sci U S A 108:6252-7. 2011
    ....
  92. pmc Identification and characterization of a new bocavirus species in gorillas
    Amit Kapoor
    Center for Infection and Immunity, Columbia University, New York, New York, United States of America
    PLoS ONE 5:e11948. 2010
    ..GBoV is the first non-human primate bocavirus identified and provides new insights into the genetic diversity and evolution of this highly prevalent and recently discovered group of parvoviruses...
  93. pmc Detection of novel astroviruses in urban brown rats and previously known astroviruses in humans
    Daniel K W Chu
    State Key Laboratory for Emerging Infectious Diseases, Department of Microbiology and the Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong SAR
    J Gen Virol 91:2457-62. 2010
    ..These rat astroviruses were phylogenetically related to recently discovered human astroviruses MLB1 and MLB2, suggesting that the MLB viruses and these novel rat astroviruses may share a common ancestor...
  94. pmc Patterns and risk factors of helminthiasis and anemia in a rural and a peri-urban community in Zanzibar, in the context of helminth control programs
    Stefanie Knopp
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 4:e681. 2010
    ..The purpose of this study was to determine patterns and risk factors of helminth infections and anemia in a rural and a peri-urban community of Zanzibar, Tanzania, in the context of national helminth control programs...
  95. pmc Human helminth co-infection: no evidence of common genetic control of hookworm and Schistosoma mansoni infection intensity in a Brazilian community
    Rachel L Pullan
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Int J Parasitol 40:299-306. 2010
    ....
  96. ncbi MM3-ELISA detection of Fasciola hepatica coproantigens in preserved human stool samples
    Florencio M Ubeira
    Laboratorio de Parasitologia, Facultad de Farmacia, Universidad de Santiago de Compostela, Santiago de Compostela, Spain
    Am J Trop Med Hyg 81:156-62. 2009
    ..We concluded that the MM3-COPRO ELISA combined with the use of CoproGuard may be a very useful tool for the diagnosis of human fascioliasis...
  97. pmc Detection of sub-clinical CWD infection in conventional test-negative deer long after oral exposure to urine and feces from CWD+ deer
    Nicholas J Haley
    Department of Microbiology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 4:e7990. 2009
    ..CWD detection methods, we have previously identified infectious prions in saliva and blood but not urine or feces of CWD+ donors...
  98. pmc Novel circular DNA viruses in stool samples of wild-living chimpanzees
    Olga Blinkova
    Blood Systems Research Institute, San Francisco and the Department of Laboratory Medicine, University of California, San Francisco, CA, USA
    J Gen Virol 91:74-86. 2010
    ..Further metagenomic studies of animal samples will greatly increase our knowledge of viral diversity and evolution...
  99. pmc Klassevirus 1, a previously undescribed member of the family Picornaviridae, is globally widespread
    Lori R Holtz
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Virol J 6:86. 2009
    ..In an effort to identify novel viruses that may be causal agents of diarrhea, we used high throughput mass sequencing to analyze stool samples collected from patients with acute diarrhea...
  100. pmc Asymptomatic deer excrete infectious prions in faeces
    GULTEKIN TAMGUNEY
    Institute for Neurodegenerative Diseases, University of California, San Francisco, California 94143 USA
    Nature 461:529-32. 2009
    ....
  101. doi Viral agents of acute gastroenteritis in hospitalized children in Greece
    S Levidiotou
    Department of Microbiology, Medical School, University of Ioannina, Ioannina, Greece
    Clin Microbiol Infect 15:596-8. 2009
    ....

Research Grants79

  1. Prophylactic and Therapeutic Immunization against H. pylori in Rhesus Macaques
    JAY SOLNICK; Fiscal Year: 2007
    ..We will also examine BabA- and BabB-specific antibodies in serum, gastric juice, and feces, as well as histopathology to evaluate inflammation and the topography of infection...
  2. Hepatic Cholesteryl Ester Metabolism and Cholesterol Elimination
    Shobha Ghosh; Fiscal Year: 2010
    ..ultimate elimination of cholesterol from the body as free cholesterol (FC) or bile acids that are excreted in the feces. Cholesterol associated with excess unmodified LDL as well as the cholesterol removed from the peripheral organs ..
  3. Investigations of the role of house flies as vectors for bacterial pathogens
    Dana Nayduch; Fiscal Year: 2009
    ..Adult house flies (Musca domestica L.) feed and breed on feces and other septic substrates...
  4. EFFECT OF HUMAN MILK BETA-GLUCURONIDASE ON THE NURSLING
    Glenn Gourley; Fiscal Year: 1993
    ..hepatic glucuronidation and are secreted into the intestine via the bile prior to excretion from the body in feces. During interstitial transit these glucuronides will be exposed to beta-glucuronidase in the interstitial lumen...
  5. EFFECT OF HUMAN MILK BETA-GLUCURONIDASE ON THE NURSLING
    Glenn Gourley; Fiscal Year: 1992
    ..hepatic glucuronidation and are secreted into the intestine via the bile prior to excretion from the body in feces. During interstitial transit these glucuronides will be exposed to beta-glucuronidase in the interstitial lumen...
  6. NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINS
    Frances Walker; Fiscal Year: 2009
    ..in obtaining an ample blood meal, and thus make more likely the transmission of the trypanosome from the insect feces to humans...
  7. NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINS
    Frances Walker; Fiscal Year: 2009
    ..in obtaining an ample blood meal, and thus make more likely the transmission of the trypanosome from the insect feces to humans...
  8. Immunology/Molecular Biology Core
    Manuela Verastegui; Fiscal Year: 2007
    ..Hemoculture of blood from humans, animals and T. infestans feces, and xenodiagnosis in guinea pigs, will all be performed on site either in Arequipa or Santa Cruz...
  9. NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINS
    FRANCES ANN WALKER; Fiscal Year: 2010
    ..in obtaining an ample blood meal, and thus make more likely the transmission of the trypanosome from the insect feces to humans...
  10. Targeted screening for Taenia solium tapeworms
    SETH E O apos NEAL; Fiscal Year: 2010
    ..It occurs when someone ingests Taenia solium eggs passed in the feces of a pork tapeworm carrier...
  11. Evo-epidemiology of Scistosoma mansoni in children in Kenya
    ERIC SAMUEL LOKER; Fiscal Year: 2010
    ..increases with subject age (aged 6 to 14) and infection intensity (ranging from 1 to >400 eggs/gram of feces), and whether worm populations exhibit signs of clonality as a result of restricted opportunities for infection...
  12. Evo-epidemiology of Scistosoma mansoni in children in Kenya
    ERIC LOKER; Fiscal Year: 2009
    ..increases with subject age (aged 6 to 14) and infection intensity (ranging from 1 to >400 eggs/gram of feces), and whether worm populations exhibit signs of clonality as a result of restricted opportunities for infection...
  13. NOC in processed meat as a likely cause of colon cancer
    Sidney S Mirvish; Fiscal Year: 2010
    ..ANC prepared from hot dog patties manufactured under standard conditions and those giving minimum ANC levels, from feces of rats fed NaNO2 or hot dogs, and from the reaction of glucose with glycine and other amino acids...
  14. Hantavirus Vaccines Based On Nonreplicating Adenoviruses
    David Johnson; Fiscal Year: 2004
    Hantaviruses are spread from infected rodents to man in dust particles derived from rodent urine, feces or saliva. Old World hantaviruses were first recognized during the Korean war, infecting thousands of U.S. troops with 10% mortality...
  15. Hantavirus Vaccines Based On Nonreplicating Adenoviruses
    David Johnson; Fiscal Year: 2005
    Hantaviruses are spread from infected rodents to man in dust particles derived from rodent urine, feces or saliva. Old World hantaviruses were first recognized during the Korean war, infecting thousands of U.S. troops with 10% mortality...
  16. Molecular Mechanisms of Chemoprevention: NRF2 Signaling
    Thomas W Kensler; Fiscal Year: 2010
    ..of isotope-dilution mass spectrometry for the quantitation of aflatoxin biomarkers in liver, blood, urine and feces in order to develop for the first time a comprehensive mass balance for the fate of the ultimate carcinogen, exo-..
  17. Molecular Mechanisms of Chemoprevention: NRF2 Signaling
    Thomas Kensler; Fiscal Year: 2009
    ..of isotope-dilution mass spectrometry for the quantitation of aflatoxin biomarkers in liver, blood, urine and feces in order to develop for the first time a comprehensive mass balance for the fate of the ultimate carcinogen, exo-..
  18. Necrotizing Enterocolitis: Prevention and Prediction
    MARK ALAN contact UNDERWOOD; Fiscal Year: 2010
    ..a series of in vitro experiments to (a) analyze biochemical and genetic properties of the bifidobacteria in the feces of infants receiving prebiotic oligosaccharides and/or probiotic microbes and (b) analyze the prebiotic properties ..
  19. Necrotizing Enterocolitis: Prevention and Prediction
    Mark Underwood; Fiscal Year: 2009
    ..a series of in vitro experiments to (a) analyze biochemical and genetic properties of the bifidobacteria in the feces of infants receiving prebiotic oligosaccharides and/or probiotic microbes and (b) analyze the prebiotic properties ..
  20. Necrotizing Enterocolitis: Prevention and Prediction
    Mark Underwood; Fiscal Year: 2009
    ..a series of in vitro experiments to (a) analyze biochemical and genetic properties of the bifidobacteria in the feces of infants receiving prebiotic oligosaccharides and/or probiotic microbes and (b) analyze the prebiotic properties ..
  21. ANALYSIS AND PHYSIOLOGY OF ISOFLAVONES IN SOYBEANS
    Kenneth Setchell; Fiscal Year: 1993
    ..daidzein and genistein, will be administered to healthy premenopausal women, and urine, serum, bile, and feces, will be collected at timed intervals for analysis of isoflavone concentrations by mass spectrometry...
  22. METABOLISM OF SOYBEAN ISOFLAVONOIDS AND LIGNANS IN MAN
    CARL ADLERCREUTZ; Fiscal Year: 1992
    ..of lignans and isoflavonoids in human biological fluids, particularly in plasma (the development of a method for feces is intended to be carried out with a subcontract in collaboration with Dr Mindy Kurzer and Dr Joanne Slavin)...
  23. ANALYSIS AND PHYSIOLOGY OF ISOFLAVONES IN SOYBEANS
    Kenneth Setchell; Fiscal Year: 1991
    ..daidzein and genistein, will be administered to healthy premenopausal women, and urine, serum, bile, and feces, will be collected at timed intervals for analysis of isoflavone concentrations by mass spectrometry...
  24. Training in Hantavirus Ecology, Virology & Clinical Investigation in the Americas
    Gregory Mertz; Fiscal Year: 2009
    ..are harbored by specific rodent species and are transmitted to man via inhalation of virus-contaminated rodent feces and urine...
  25. Training in Hantavirus Ecology, Virology & Clinical Investigation in the Americas
    GREGORY JAMES MERTZ; Fiscal Year: 2010
    ..are harbored by specific rodent species and are transmitted to man via inhalation of virus-contaminated rodent feces and urine...
  26. Training in Hantavirus Ecology, Virology & Clinical Investigation in the Americas
    Gregory Mertz; Fiscal Year: 2007
    ..are harbored by specific rodent species and are transmitted to man via inhalation of virus-contaminated rodent feces and urine...
  27. Training in Hantavirus Ecology, Virology & Clinical Investigation in the Americas
    Gregory Mertz; Fiscal Year: 2006
    ..are harbored by specific rodent species and are transmitted to man via inhalation of virus-contaminated rodent feces and urine...
  28. Parasite/Host Interactions and the Neurobiology of Fear
    Robert Sapolsky; Fiscal Year: 2006
    ..The parasite reproduces in cats, and is then excreted. Infected feces are eaten by rodents, in which Toxoplasma forms cysts in muscle and the CNS...
  29. Cholesterol Ester Hydrolysis and Cholesterol Efflux
    Shobha Ghosh; Fiscal Year: 2010
    ..enhanced the flux of cholesterol from macrophages to liver for the final elimination as bile acids into bile and feces providing direct evidence that enhanced CEH-mediated intracellular CE hydrolysis is anti-atherogenic...
  30. Gamma-tocopherol as an effective anticancer agent for colon cancer
    Qing Jiang; Fiscal Year: 2010
    ..A new metabolite of 3T, 13'-carboxychormanol, which is detected in significant amounts in feces, is an even stronger inhibitor of COXs and 5-LOX than 3T...
  31. Quantitation of Tocopherol Metabolism in Humans
    Andrew Clifford; Fiscal Year: 2009
    ..Erythrocytes, lymphocytes, and platelets will also be separated. Urine and feces will be collected until 30 days post dose...
  32. Gamma-tocopherol as an effective anticancer agent for colon cancer
    Qing Jiang; Fiscal Year: 2009
    ..A new metabolite of 3T, 13'-carboxychormanol, which is detected in significant amounts in feces, is an even stronger inhibitor of COXs and 5-LOX than 3T...
  33. Cholesterol Ester Hydrolysis and Cholesterol Efflux
    Shobha Ghosh; Fiscal Year: 2009
    ..enhanced the flux of cholesterol from macrophages to liver for the final elimination as bile acids into bile and feces providing direct evidence that enhanced CEH-mediated intracellular CE hydrolysis is anti-atherogenic...
  34. Parasite/Host Interactions and the Neurobiology of Fear
    Robert Sapolsky; Fiscal Year: 2005
    ..The parasite reproduces in cats, and is then excreted. Infected feces are eaten by rodents, in which Toxoplasma forms cysts in muscle and the CNS...
  35. Quantitation of Tocopherol Metabolism in Humans
    ANDREW JOSEPH CLIFFORD; Fiscal Year: 2010
    ..Erythrocytes, lymphocytes, and platelets will also be separated. Urine and feces will be collected until 30 days post dose...
  36. CWD: A Model of Prion Transmission via Saliva and Urine
    NICHOLAS JAMES HALEY; Fiscal Year: 2010
    ..CWD PrPres has been shown to be present and transmissible in various excreta, including saliva, blood, urine and feces of infected deer, though other biological samples may also serve as routes of transmission between cervids...
  37. DIET AND ITS EFFECT ON ENZYMES LINKED TO COLON CANCER
    Sherwood Gorbach; Fiscal Year: 1980
    ..Meat-fed rats had more naphthylamine in their feces after being orally given nitronaphthalene, demonstrating that the elevated nitroreductase levels resulting from ..
  38. Evaluation of Salmonella in Symptomatic and Asymptomatic Pets
    Timothy S Frana; Fiscal Year: 2012
    ..Salmonella can be present in many different environments, including water, soil, insects, feces, wild and farm raised animals, raw foods, surfaces and animal feeds...
  39. Evaluation of Salmonella in Symptomatic and Asymptomatic Pets: Study for the Vet-
    Shelley Rankin; Fiscal Year: 2012
    ..100 fecal samples will be collected from dogs in each group. Feces will be pre-enriched in Buffered Peptone Water at 35 [unreadable]C overnight and then screened with a rapid ..
  40. MULTIDISCIPLINARY STUDY OF PCBS & PCDFS AT A WASTE SITE
    David Carpenter; Fiscal Year: 1990
    ..nursing mothers will be correlated with levels in body fluids, including breast milk, and with levels in urine and feces in infants; II) a study of pre- and postnatal exposure of rat pups to PCBs and PCDFs, correlating pregnancy ..
  41. CLINICAL EXPERIMENT OF HELICOBACTER PYLORI TRANSMISSION
    Julie Parsonnet; Fiscal Year: 1999
    ..pylori organisms are present in vomitus, air samples obtained during vomiting, saliva and/or feces. To do this, we intend to conduct a clinical experiment in 30 H. pylori infected volunteers...
  42. EQUIPMENT REQUEST
    DONALD MAUL; Fiscal Year: 1991
    ..The floors are wooden slats lying directly on the sealed concrete floor so cleaning feces from between and beneath the slats, while keeping the animals clean and dry, is difficult...
  43. PMCA Detection of CWD Infection in Cervid and Non-Cervid Species
    EDWARD ARTHUR HOOVER; Fiscal Year: 2010
    ..serial protein misfolding cyclic amplification (sPMCA) to amplify and detect PrPCWD in saliva, blood, urine, and feces of infected deer...
  44. PMCA Detection of CWD Infection in Cervid and Non-Cervid Species
    Edward Hoover; Fiscal Year: 2009
    ..serial protein misfolding cyclic amplification (sPMCA) to amplify and detect PrPCWD in saliva, blood, urine, and feces of infected deer...
  45. PATHOPHYSIOLOGIC EFFECTS OF PERITONITIS
    Harvey Sugerman; Fiscal Year: 1980
    ..After 48 hours, frozen, processed human feces mixed with barium sulfate will be injected under pressure into the gallbladder...
  46. MOLECULAR AND CELLULAR PATHOGENESES OF URINARY INFECTION
    John Warren; Fiscal Year: 1999
    ..We have bacterial isolates from pyelonephritis, cystitis, and asymptomatic bacteriuric cases and from feces of controls. Investigators in our group now routinely manipulate bacterial genes...
  47. INFECTION IN ELBW INFANTS:PROTECTION WITH MOTHER'S MILK
    Nancy Rodriguez; Fiscal Year: 2004
    ..and excreted in the infant's urine; lactoferrin, with enhanced bacteriocidal properties, has been recaptured from feces. Thus, OMM may provide significant protection for ELBW infants; additionally, OMM is inexpensive, and facilitates ..
  48. COLON CANCER PREVENTION
    David Alberts; Fiscal Year: 1999
    ..study of the effect of wheat bran fiber on adenomatous polyp recurrence and bile acid concentrations in blood and feces, and rectal mucosal proliferation rates in patients with adenomatous colorectal polyps...
  49. INFECTION IN ELBW INFANTS:PROTECTION WITH MOTHER'S MILK
    Nancy Rodriguez; Fiscal Year: 2005
    ..and excreted in the infant's urine; lactoferrin, with enhanced bacteriocidal properties, has been recaptured from feces. Thus, OMM may provide significant protection for ELBW infants; additionally, OMM is inexpensive, and facilitates ..
  50. ANAEROBIC METABOLISM OF MUTAGENS IN HUMAN FOODS
    David Kingston; Fiscal Year: 1990
    ..involve synthesizing the radiolabeled carcinogens and incubating them, under controlled conditions, with human feces and cultures of the colonic flora. Any metabolic products are purified by organic extractions and TLC and HPLC...
  51. REGULATION OF ENTERIC HYPEROXALURI BY OXALOBACTER
    AMMON PECK; Fiscal Year: 2000
    ..per gram feces and the frequency of recurrent urolithiasis, inflammatory bowel disease and hyperoxaluria/nephrocalcinosis in ..
  52. FACILITY RENOVATION AND ANNENBERG CAGE WASH FACILITIY
    Kenneth Davis; Fiscal Year: 2003
    ..has recurrent leaks onto the lower research floors, exposing personnel to hazardous waste water (primate and swine feces) from the unit and associated plumbing...
  53. REGULATION OF ENTERIC HYPEROXALURI BY OXALOBACTER
    AMMON PECK; Fiscal Year: 2001
    ..per gram feces and the frequency of recurrent urolithiasis, inflammatory bowel disease and hyperoxaluria/nephrocalcinosis in ..
  54. REGULATION OF ENTERIC HYPEROXALURI BY OXALOBACTER
    AMMON PECK; Fiscal Year: 1999
    ..per gram feces and the frequency of recurrent urolithiasis, inflammatory bowel disease and hyperoxaluria/nephrocalcinosis in ..
  55. IMMUNITY AND PATHOGENESIS OF A NOVEL NOROVIRUS
    Herbert W Virgin; Fiscal Year: 2010
    ..Interestingly, certain MNV strains persistently replicate in intestine of WT mice and are shed in feces for weeks despite a significant immune response...
  56. IMMUNITY AND PATHOGENESIS OF A NOVEL NOROVIRUS
    Herbert W Virgin; Fiscal Year: 2010
    ..Interestingly, certain MNV strains persistently replicate in intestine of WT mice and are shed in feces for weeks despite a significant immune response...
  57. IMMUNITY AND PATHOGENESIS OF A NOVEL NOROVIRUS
    Herbert Virgin; Fiscal Year: 2009
    ..Interestingly, certain MNV strains persistently replicate in intestine of WT mice and are shed in feces for weeks despite a significant immune response...
  58. BIOTIN REQUIREMENTS OF INFANTS
    Donald Mock; Fiscal Year: 1990
    ..aims are 1) to accurately measure the total content of biotin and biotin analogs in infant formula, urine, and feces, 2) to determine biotin balance in normal, formula-fed infants fed formula with biotin supplementation at levels ..
  59. OLIGODEOXYNECLEOTIDE INHIBITION OF CELL PROLIFERATION
    Eric Wickstrom; Fiscal Year: 1993
    ..Pharmacokinetics of the oligomers will be measured in serum, urine, and feces. In the event that tumors are significantly reduced in size and growth rate by antisense or antigene treatment, ..
  60. IMPROVING VIRTUAL COLONOSCOPY WITH COMPUTER DETECTION
    David Vining; Fiscal Year: 2000
    ..To optimize bowel preparation with digital subtraction of opacified feces and controlled gas distention; and 4...
  61. IMPROVING VIRTUAL COLONOSCOPY WITH COMPUTER DETECTION
    David Vining; Fiscal Year: 1999
    ..To optimize bowel preparation with digital subtraction of opacified feces and controlled gas distention; and 4...
  62. IMPROVING VIRTUAL COLONOSCOPY WITH COMPUTER DETECTION
    Peter Santago; Fiscal Year: 2001
    ..To optimize bowel preparation with digital subtraction of opacified feces and controlled gas distention; and 4...
  63. Quantitation of In Vivo Human Lutein Metabolism
    Andrew Clifford; Fiscal Year: 2009
    ..The five lipoprotein classes will be separated from plasma in a single ultracentrifugation. Urine and feces will be collected until 21 days post dose...
  64. NOVEL E. COLI 0157:H7 INTESTINAL COLONIZATION FACTORS
    JAMES KAPER; Fiscal Year: 2005
    ..Infection begins by ingestion of food or water that is contaminated with EHEC, often from contact with cattle feces, the primary reservoir of the organism. The extremely infectious dose required for disease, ca...
  65. Impact of Fiber Fermentation on Fecal Incontinence
    Donna Bliss; Fiscal Year: 2006
    unreadable] DESCRIPTION (provided by applicant): Fecal incontinence (FI), the involuntary leakage of feces, is a chronic problem with debilitating effects on health and well-being...
  66. NOVEL E. COLI 0157:H7 INTESTINAL COLONIZATION FACTORS
    JAMES KAPER; Fiscal Year: 2009
    ..Infection begins by ingestion of food or water that is contaminated with EHEC, often from contact with cattle feces, the primary reservoir of the organism. The extremely infectious dose required for disease, ca...
  67. NOVEL E. COLI 0157:H7 INTESTINAL COLONIZATION FACTORS
    JAMES KAPER; Fiscal Year: 2006
    ..Infection begins by ingestion of food or water that is contaminated with EHEC, often from contact with cattle feces, the primary reservoir of the organism. The extremely infectious dose required for disease, ca...
  68. Impact of Fiber Fermentation on Fecal Incontinence
    Donna Bliss; Fiscal Year: 2004
    Fecal incontinence (FI), the involuntary leakage of feces, is a chronic problem with debilitating effects on health and well-being...
  69. Impact of Fiber Fermentation on Fecal Incontinence
    Donna Bliss; Fiscal Year: 2007
    unreadable] DESCRIPTION (provided by applicant): Fecal incontinence (FI), the involuntary leakage of feces, is a chronic problem with debilitating effects on health and well-being...
  70. NOVEL E. COLI 0157:H7 INTESTINAL COLONIZATION FACTORS
    JAMES KAPER; Fiscal Year: 2007
    ..Infection begins by ingestion of food or water that is contaminated with EHEC, often from contact with cattle feces, the primary reservoir of the organism. The extremely infectious dose required for disease, ca...
  71. Impact of Fiber Fermentation on Fecal Incontinence
    Donna Bliss; Fiscal Year: 2003
    Fecal incontinence (FI), the involuntary leakage of feces, is a chronic problem with debilitating effects on health and well-being...
  72. RED CLOVER PHYTOESTROGENS EFFECTS ON ATHEROSCLEROSIS
    James Goodrich; Fiscal Year: 1999
    ..LDL receptors which in turn removes cholesterol from the circulation to make bile acids that are excreted in the feces. Additionally a bile acid sequestrant such as the undigested fraction of soy protein is essential to prevent ..
  73. Impact of Fiber Fermentation on Fecal Incontinence
    Donna Bliss; Fiscal Year: 2005
    Fecal incontinence (FI), the involuntary leakage of feces, is a chronic problem with debilitating effects on health and well-being...