saliva

Summary

Summary: The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin.

Top Publications

  1. pmc A multiplex assay for the simultaneous detection of antibodies against 15 Plasmodium falciparum and Anopheles gambiae saliva antigens
    Elena Ambrosino
    IRBA and UMR6236, Marseille, France
    Malar J 9:317. 2010
  2. ncbi Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research
    Sally S Dickerson
    Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA
    Psychol Bull 130:355-91. 2004
  3. pmc Exosomes from human saliva as a source of microRNA biomarkers
    A Michael
    Sjögren s Syndrome Clinic, Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, Bethesda, MD 20892, USA
    Oral Dis 16:34-8. 2010
  4. ncbi Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change
    Jens C Pruessner
    McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada
    Psychoneuroendocrinology 28:916-31. 2003
  5. pmc The majority of microRNAs detectable in serum and saliva is concentrated in exosomes
    Alessia Gallo
    Sjögren s Syndrome Clinic, Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 7:e30679. 2012
  6. pmc The role of saliva in tick feeding
    Ivo M B Francischetti
    Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda MD, USA
    Front Biosci (Landmark Ed) 14:2051-88. 2009
  7. pmc Structure and function of a "yellow" protein from saliva of the sand fly Lutzomyia longipalpis that confers protective immunity against Leishmania major infection
    Xueqing Xu
    Laboratory of Malaria and Vector Research, NIAID, National Institutes of Health, Rockville, Maryland 20852, USA
    J Biol Chem 286:32383-93. 2011
  8. ncbi Pyrosequencing analysis of the oral microflora of healthy adults
    B J F Keijser
    TNO Quality of Life, Business Unit Food and Biotechnology Innovations, Microbial Genomics Group, Zeist, The Netherlands
    J Dent Res 87:1016-20. 2008
  9. pmc Study of inter- and intra-individual variations in the salivary microbiota
    Vladimir Lazarevic
    Genomic Research Laboratory, Geneva University Hospitals, Rue Gabrielle Perret Gentil 4, CH 1211 Geneva 14, Switzerland
    BMC Genomics 11:523. 2010
  10. doi Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study
    Sophie A Vreeburg
    Department of Psychiatry, VU University Medical Center, A J Ernststraat 887, 1081 HL Amsterdam, The Netherlands
    Arch Gen Psychiatry 66:617-26. 2009

Detail Information

Publications348 found, 100 shown here

  1. pmc A multiplex assay for the simultaneous detection of antibodies against 15 Plasmodium falciparum and Anopheles gambiae saliva antigens
    Elena Ambrosino
    IRBA and UMR6236, Marseille, France
    Malar J 9:317. 2010
    ..Thus, the aim of this study was to develop a sensitive tool to assess the exposure to malaria or to bites from the vector Anopheles gambiae, despite anti-malarial prophylactic treatment...
  2. ncbi Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research
    Sally S Dickerson
    Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA
    Psychol Bull 130:355-91. 2004
    ..These findings are consistent with the animal literature on the physiological effects of uncontrollable social threat and contradict the belief that cortisol is responsive to all types of stressors...
  3. pmc Exosomes from human saliva as a source of microRNA biomarkers
    A Michael
    Sjögren s Syndrome Clinic, Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, Bethesda, MD 20892, USA
    Oral Dis 16:34-8. 2010
    The aim of this study was to examine the presence of microRNAs (miRNAs) within exosomes isolated from human saliva and to optimize and test methods for successful downstream applications.
  4. ncbi Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change
    Jens C Pruessner
    McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada
    Psychoneuroendocrinology 28:916-31. 2003
    ..It is shown that depending on which formula is used, different associations with other variables may emerge. Consequently, it is recommended to employ both formulas when analyzing data sets with repeated measures...
  5. pmc The majority of microRNAs detectable in serum and saliva is concentrated in exosomes
    Alessia Gallo
    Sjögren s Syndrome Clinic, Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 7:e30679. 2012
    ..We investigated if the majority of miRNas in serum and saliva are free-circulating or concentrated in exosomes...
  6. pmc The role of saliva in tick feeding
    Ivo M B Francischetti
    Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda MD, USA
    Front Biosci (Landmark Ed) 14:2051-88. 2009
    ..This supplemental file is accessble fromhttp://exon.niaid.nih.gov/transcriptome/tick_review/Sup-Table-1.xls.gz...
  7. pmc Structure and function of a "yellow" protein from saliva of the sand fly Lutzomyia longipalpis that confers protective immunity against Leishmania major infection
    Xueqing Xu
    Laboratory of Malaria and Vector Research, NIAID, National Institutes of Health, Rockville, Maryland 20852, USA
    J Biol Chem 286:32383-93. 2011
    ..longipalpis saliva. Additionally, splenocytes of exposed mice produce IFN-γ upon stimulation with LJM11, demonstrating the systemic ..
  8. ncbi Pyrosequencing analysis of the oral microflora of healthy adults
    B J F Keijser
    TNO Quality of Life, Business Unit Food and Biotechnology Innovations, Microbial Genomics Group, Zeist, The Netherlands
    J Dent Res 87:1016-20. 2008
    ..We hypothesized that the species richness of human oral microflora is underestimated. Saliva and supragingival plaque were sampled from 71 and 98 healthy adults, respectively...
  9. pmc Study of inter- and intra-individual variations in the salivary microbiota
    Vladimir Lazarevic
    Genomic Research Laboratory, Geneva University Hospitals, Rue Gabrielle Perret Gentil 4, CH 1211 Geneva 14, Switzerland
    BMC Genomics 11:523. 2010
    ..Culture-independent approaches provide the best means to assess the diversity of oral bacteria because most of them remain uncultivable...
  10. doi Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study
    Sophie A Vreeburg
    Department of Psychiatry, VU University Medical Center, A J Ernststraat 887, 1081 HL Amsterdam, The Netherlands
    Arch Gen Psychiatry 66:617-26. 2009
    ..There is a central belief that depression is associated with hyperactivity of the hypothalamic-pituitary-adrenal axis, resulting in higher cortisol levels. However, results are inconsistent...
  11. ncbi Stress-induced changes in human salivary alpha-amylase activity -- associations with adrenergic activity
    Urs Markus Nater
    Institute of Psychology, Clinical Psychology and Psychotherapy, University of Zurich, Zürichbergstr 43, CH 8044 Zurich, Switzerland
    Psychoneuroendocrinology 31:49-58. 2006
    ..Since it does not seem to be closely related to other biological stress markers such as catecholamines and cortisol, salivary alpha-amylase may be a useful additional parameter for the measurement of stress...
  12. pmc Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages
    Cecilia Lässer
    Krefting Research Centre, Sahlgrenska Academy, University of Gothenburg, Box 424, 405 30 Gothenburg, Sweden
    J Transl Med 9:9. 2011
    ..Our aim was therefore to determine the presence of RNA in exosomes from human saliva, plasma and breast milk and whether these exosomes can be taken up by macrophages.
  13. pmc Analysis of streptococcal CRISPRs from human saliva reveals substantial sequence diversity within and between subjects over time
    David T Pride
    Department of Pathology, University of California, San Diego, La Jolla, California 92093, USA
    Genome Res 21:126-36. 2011
    ..We collected saliva from four periodontally healthy human subjects over an 11- to 17-mo time period and analyzed CRISPR sequences with ..
  14. ncbi Evaluation of the antibody response to Anopheles salivary antigens as a potential marker of risk of malaria
    Franck Remoue
    Institut de recherche pour le developpement IRD, UR24 Epidémiologie et Prévention Unit, Centre IRD de Hann, BP 1386, Dakar, Senegal
    Trans R Soc Trop Med Hyg 100:363-70. 2006
    ..The specific antibody (Ab) IgG response to saliva obtained from Anopheles gambiae mosquitoes was evaluated in young children from an area of seasonal malaria ..
  15. doi Improved performance with saliva and urine as alternative DNA sources for malaria diagnosis by mitochondrial DNA-based PCR assays
    C Putaporntip
    Department of Parasitology, Faculty of Medicine, Molecular Biology of Malaria and Opportunistic Parasites Research Unit, Chulalongkorn University, Bangkok, Thailand
    Clin Microbiol Infect 17:1484-91. 2011
    b>Saliva and urine from malaria-infected individuals contain trace amounts of Plasmodium DNA, and therefore, could be used as alternative specimens for diagnosis...
  16. pmc Discovery of markers of exposure specific to bites of Lutzomyia longipalpis, the vector of Leishmania infantum chagasi in Latin America
    Clarissa Teixeira
    Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
    PLoS Negl Trop Dis 4:e638. 2010
    ..Though some proteins are immunogenic and have potential as markers of vector exposure, their identity and vector specificity remain elusive...
  17. pmc Global diversity in the human salivary microbiome
    Ivan Nasidze
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Genome Res 19:636-43. 2009
    ..We analyzed 14,115 partial ( approximately 500 bp) 16S ribosomal RNA (rRNA) sequences from saliva samples from 120 healthy individuals (10 individuals from each of 12 worldwide locations)...
  18. ncbi Validation of self-reported smoking status using saliva cotinine: a rapid semiquantitative dipstick method
    Norman J Montalto
    Acordia National Wells Fargo, 602 Virginia St E, Charleston, West Virginia, 25327 1921, USA
    Cancer Epidemiol Biomarkers Prev 16:1858-62. 2007
    ..for verifying smoking status in individuals by measurement of cotinine, the primary metabolite of nicotine, in saliva samples using an immunochromatographic strip in a "dipstick" format compared with liquid chromatography/mass ..
  19. doi Salivary cortisol as a biomarker in stress research
    Dirk H Hellhammer
    Psychology, Department of Clinical and Physiological Psychology, University of Trier, Johanniterufer 15, 54290 Trier, Germany
    Psychoneuroendocrinology 34:163-71. 2009
    ....
  20. pmc Diagnosis of dengue virus infection by detection of specific immunoglobulin M (IgM) and IgA antibodies in serum and saliva
    Angel Balmaseda
    National Center for Diagnosis and Reference, Ministry of Health, Granada, Nicaragua
    Clin Diagn Lab Immunol 10:317-22. 2003
    ..dengue virus (DEN) infection, the detection of DEN-specific immunoglobulin M (IgM) and IgA antibodies in serum and saliva specimens was assessed in 147 patients with symptoms of DEN infection seen at the Ministry of Health in Nicaragua...
  21. ncbi Antibody response against saliva antigens of Anopheles gambiae and Aedes aegypti in travellers in tropical Africa
    Eve Orlandi-Pradines
    Unité de recherche en biologie et en épidémiologie parasitaires, Institut de Medecine Tropicale du Service de Sante des Armees, Parc le Pharo, BP 46, 13998 Marseille Armees, France
    Microbes Infect 9:1454-62. 2007
    ..The IgM and IgG antibody responses of 88 French soldiers against the saliva of Anopheles gambiae and Aedes aegypti were evaluated before and after a 5-month journey in tropical Africa...
  22. pmc Enhanced Leishmania braziliensis infection following pre-exposure to sandfly saliva
    Tatiana R de Moura
    Centro de Pesquisas Goncalo Moniz, Fundação Oswaldo Cruz FIOCRUZ, Salvador, Brazil
    PLoS Negl Trop Dis 1:e84. 2007
    Sand fly saliva has an array of pharmacological and immunomodulatory components, and immunity to saliva protects against Leishmania infection...
  23. ncbi The diagnostic applications of saliva--a review
    Eliaz Kaufman
    Division of Periodontics, Columbia University, School of Dental and Oral Surgery, 630 West 168th Street, PH 7E, Room 110, New York, NY 10032, USA
    Crit Rev Oral Biol Med 13:197-212. 2002
    This review examines the diagnostic application of saliva for systemic diseases. As a diagnostic fluid, saliva offers distinctive advantages over serum because it can be collected non-invasively by individuals with modest training...
  24. doi Analysis of oral microbiota in children with dental caries by PCR-DGGE and barcoded pyrosequencing
    Zongxin Ling
    State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China
    Microb Ecol 60:677-90. 2010
    ..and PCR-denaturing gradient gel electrophoresis (DGGE) to examine bacterial diversity of oral microbiota in saliva and supragingival plaques from 60 children aged 3 to 6 years old with and without dental caries from China...
  25. pmc Chikungunya virus and Aedes mosquitoes: saliva is infectious as soon as two days after oral infection
    Mathieu Dubrulle
    Institut Pasteur, Génétique Moléculaire des Bunyavirus, Paris, France
    PLoS ONE 4:e5895. 2009
    ..albopictus. As Ae. albopictus tends to replace Ae. aegypti in many regions, one question remained: is Ae. albopictus as efficient as Ae. aegypti to transmit the variant E1-226V of CHIKV?..
  26. pmc Measurement of recent exposure to Phlebotomus argentipes, the vector of Indian visceral Leishmaniasis, by using human antibody responses to sand fly saliva
    Meredith F Clements
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Trop Med Hyg 82:801-7. 2010
    Antibody (IgG) responses to the saliva of Phlebotomus argentipes were investigated using serum samples from regions of India endemic and non-endemic for visceral leishmaniasis (VL)...
  27. pmc Exploring the oral microbiota of children at various developmental stages of their dentition in the relation to their oral health
    Wim Crielaard
    TNO Quality of Life, Business Unit Food and Biotechnology Innovations, Microbial Genomics Group, Utrechtseweg 48, Zeist, The Netherlands
    BMC Med Genomics 4:22. 2011
    ..The microbial composition of saliva was assessed by barcoded pyrosequencing of the V5-V6 hypervariable regions of the 16 S rRNA, as well as by using ..
  28. pmc Human antibody response to Anopheles gambiae saliva: an immuno-epidemiological biomarker to evaluate the efficacy of insecticide-treated nets in malaria vector control
    Papa M Drame
    Institut de recherche pour le developpement IRD, UR024 Epidémiologie et Prévention Unit, Dakar, Senegal
    Am J Trop Med Hyg 83:115-21. 2010
    ..This study investigates a potential immunological marker, based on human antibody responses to Anopheles saliva, as a new indicator to evaluate the efficacy of insecticide-treated nets (ITNs)...
  29. ncbi Detection of species-specific antibody response of humans and mice bitten by sand flies
    I Rohousova
    Department of Parasitology, Faculty of Science, Charles University, Vinicna 7, 128 44 Prague 2, Czech Republic
    Parasitology 130:493-9. 2005
    Sand fly saliva plays an important role in Leishmania transmission. We characterized the host antibody response to saliva from 3 sand fly species...
  30. ncbi Herbivory: caterpillar saliva beats plant defences
    Richard O Musser
    Department of Entomology, University of Arkansas, Fayetteville, Arkansas 72701, USA
    Nature 416:599-600. 2002
    ..We find that the enzyme glucose oxidase counteracts the production of nicotine induced by the caterpillar feeding on the plant...
  31. pmc Influence of cranberry proanthocyanidins on formation of biofilms by Streptococcus mutans on saliva-coated apatitic surface and on dental caries development in vivo
    H Koo
    Eastman Department of Dentistry, University of Rochester Medical Center, Rochester, NY 14620, USA hyun_koo urmc rochester edu
    Caries Res 44:116-26. 2010
    ..mutans biofilm formation on saliva-coated hydroxyapatite surface, and on dental caries development in Sprague-Dawley rats...
  32. doi Smoke-free homes in England: prevalence, trends and validation by cotinine in children
    M J Jarvis
    Health Behaviour Research Centre, Department of Epidemiology and Public Health, University College London, London, UK
    Tob Control 18:491-5. 2009
    ..Main outcome measures were cotinine measured in saliva, smoke-free homes defined by "no" response to "Does anyone smoke inside this house/flat on most days?", self-..
  33. doi Salivary alpha-amylase as a non-invasive biomarker for the sympathetic nervous system: current state of research
    U M Nater
    University of Zurich, Institute of Psychology, Department of Clinical Psychology and Psychotherapy, Zurich, Switzerland
    Psychoneuroendocrinology 34:486-96. 2009
    ..It critically discusses how sAA might reflect changes in the autonomic nervous system. Finally, current and future fields for the application of sAA measurement are outlined...
  34. pmc Characterization of the antibody response to the saliva of Phlebotomus papatasi in people living in endemic areas of cutaneous leishmaniasis
    Soumaya Marzouki
    Department of Clinical Immunology, Institut Pasteur de Tunis, 13 Place Pasteur, Le Belvedere, Tunisia
    Am J Trop Med Hyg 84:653-61. 2011
    Important data obtained in mice raise the possibility that immunization against the saliva of sand flies could protect from leishmaniasis...
  35. ncbi Regulation of salivary gland function by autonomic nerves
    Gordon B Proctor
    Salivary Research Unit, King s College London Dental Institute, Floor 17 Guy s Tower, London SE1 9RT, UK
    Auton Neurosci 133:3-18. 2007
    Oral homeostasis is dependent upon saliva and its content of proteins. Reflex salivary flow occurs at a low 'resting' rate and for short periods of the day more intense taste or chewing stimuli evoke up to ten fold increases in salivation...
  36. pmc Cellular and humoral immunity following Snow Mountain virus challenge
    Lisa Lindesmith
    School of Public Health, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, USA
    J Virol 79:2900-9. 2005
    ..We assessed the cellular and humoral immune response and infection by analyzing stool, serum, saliva, and peripheral blood mononuclear cell (PBMC) responses pre- and postchallenge...
  37. pmc Anti-Anopheles darlingi saliva antibodies as marker of Plasmodium vivax infection and clinical immunity in the Brazilian Amazon
    Bruno Bezerril Andrade
    Centro de Pesquisas Gonçalo Moniz FIOCRUZ, Bahia, Brazil
    Malar J 8:121. 2009
    ..Thus, innovative strategies are needed to reduce disease burden. The malaria vectors, through the injection of saliva into the host skin, play important role on disease transmission and may influence malaria morbidity...
  38. pmc The enhancement of arbovirus transmission and disease by mosquito saliva is associated with modulation of the host immune response
    Bradley S Schneider
    Institut Pasteur, Departement de Parasitologie, Unités de Réponses Précoces aux Parasites et Immunopathologie, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Trans R Soc Trop Med Hyg 102:400-8. 2008
    ..Arboviruses, including dengue and West Nile virus, are injected into vertebrates within mosquito saliva during mosquito feeding...
  39. ncbi Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels
    T Ma
    Departments of Medicine, Physiology, and Pediatrics, Cardiovascular Research Institute, University of California, San Francisco, California 94143 0521, USA
    J Biol Chem 274:20071-4. 1999
    ..Pilocarpine-stimulated saliva production was reduced by more than 60% in AQP5 knockout mice...
  40. doi Diagnostic potential of saliva: current state and future applications
    Tina Pfaffe
    Technical University of Applied Science, Wildau, Germany
    Clin Chem 57:675-87. 2011
    Over the past 10 years, the use of saliva as a diagnostic fluid has gained attention and has become a translational research success story...
  41. pmc Saliva microbiomes distinguish caries-active from healthy human populations
    Fang Yang
    Department of Operative Dentistry and Endodontics, Guanghua School and Hospital of Stomatology and Institute of Stomatological Research, Sun Yat Sen University, Guangzhou, Guangdong, China
    ISME J 6:1-10. 2012
    ..technologies, we report the most in-depth, comprehensive and collaborated view to date of the adult saliva microbiomes in pilot populations of 19 caries-active and 26 healthy human hosts...
  42. doi Investigation into the cross-correlation of salivary cortisol and alpha-amylase responses to psychological stress
    Veronika Engert
    Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada
    Psychoneuroendocrinology 36:1294-302. 2011
    ..of 50 male participants were exposed to a psychological laboratory stressor with high frequency (2-min interval) saliva sampling in two independent studies...
  43. doi Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma
    Andre Lopes Carvalho
    Department of Otolaryngology Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 0910, USA
    Clin Cancer Res 14:97-107. 2008
    ..To evaluate aberrant promoter hypermethylation of candidate tumor suppressor genes as a means to detect epigenetic alterations specific to solid tumors, including head and neck squamous cell carcinoma (HNSCC)...
  44. pmc Molecular sabotage of plant defense by aphid saliva
    Torsten Will
    Plant Cell Biology Research Group, Institute of General Botany, Justus Liebig University, Senckenbergstrasse 17 21, D 35390 Giessen, Germany
    Proc Natl Acad Sci U S A 104:10536-41. 2007
    ..Occlusion mechanisms are calcium-triggered and may be prevented by chemical constituents in aphid saliva injected into sieve tubes before and during feeding...
  45. doi Assessing salivary cortisol in large-scale, epidemiological research
    Emma K Adam
    School of Education and Social Policy and Institute for Policy Research, Northwestern University, United States
    Psychoneuroendocrinology 34:1423-36. 2009
    ....
  46. ncbi Salivary secretions by aphids interacting with proteins of phloem wound responses
    W Fred Tjallingii
    Laboratory of Entomology, Wageningen University, 6700 EH Wageningen, The Netherlands
    J Exp Bot 57:739-45. 2006
    ..e. the stylets. It seems that in order to prevent protein clogging inside a sieve element, ejection of watery saliva plays an important role...
  47. ncbi Effect of orthodontic treatment on saliva, plaque and the levels of Streptococcus mutans and Lactobacillus
    Edith Lara-Carrillo
    Department of Orthodontics, Research Center, School of Dentistry, Universidad Autonoma del Estado de Mexico, Toluca, Estado de Mexico, Mexico
    Med Oral Patol Oral Cir Bucal 15:e924-9. 2010
    ..The aim of this study was to identify changes in the oral environment with clinical, salivary and bacterial risk markers after placement of fixed orthodontic appliances on permanent dentition...
  48. pmc Deconstructing tick saliva: non-protein molecules with potent immunomodulatory properties
    Carlo José F Oliveira
    Department of Biochemistry and Immunology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil
    J Biol Chem 286:10960-9. 2011
    ..blood-sucking ectoparasite arthropods that suppress host immunity by secreting immunomodulatory molecules in their saliva. Here, compounds present in Rhipicephalus sanguineus tick saliva with immunomodulatory effects on DC ..
  49. doi Comparative analysis of human saliva microbiome diversity by barcoded pyrosequencing and cloning approaches
    Ivan Nasidze
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Anal Biochem 391:64-8. 2009
    ..with a barcoded pyrosequencing method to see whether the latter accurately describes microbiome diversity in human saliva. Our results indicate that despite the shorter read lengths, the pyrosequencing approach provides a description of ..
  50. pmc Isolation and detection of Campylobacter concisus from saliva of healthy individuals and patients with inflammatory bowel disease
    Li Zhang
    School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, Sydney, New South Wales 2052, Australia
    J Clin Microbiol 48:2965-7. 2010
    The presence of Campylobacter concisus in the saliva of healthy individuals and patients with inflammatory bowel disease (IBD) was examined. C...
  51. ncbi Stability of salivary steroids: the influences of storage, food and dental care
    M Groschl
    Hospital for Children and Adolescents, Friedrich Alexander University, Erlangen Nurnberg, Germany
    Steroids 66:737-41. 2001
    ..b>Saliva samples of healthy adults (n = 15; m:8; f:7) were collected directly before and after dental care, and directly ..
  52. pmc Nanostructural and transcriptomic analyses of human saliva derived exosomes
    VISWANATHAN PALANISAMY
    Department of Craniofacial Biology, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America
    PLoS ONE 5:e8577. 2010
    ..They are ubiquitous in most body fluids (breast milk, saliva, blood, urine, malignant ascites, amniotic, bronchoalveolar lavage, and synovial fluids)...
  53. ncbi HPA axis responses to laboratory psychosocial stress in healthy elderly adults, younger adults, and children: impact of age and gender
    B M Kudielka
    Department of Behavioural Sciences, Swiss Federal Institute of Technology ETH, Turnerstr 1, CH 8092, Zurich, Switzerland
    Psychoneuroendocrinology 29:83-98. 2004
    ..It can be speculated if corticosteroid binding globulin (CBG) and/or sex steroids are important modulators of these effects...
  54. ncbi PCR detection and identification of oral streptococci in saliva samples using gtf genes
    Tomonori Hoshino
    Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry, Suita shi Osaka 565 0871, Japan
    Diagn Microbiol Infect Dis 48:195-9. 2004
    ..Further, we developed a simple method to extract the bacterial DNA from saliva. Using the resultant DNA as a template, the proposed PCR detection was performed...
  55. ncbi A microfluidic system for saliva-based detection of infectious diseases
    Zongyuan Chen
    University of Pennsylvania School of Engineering and Applied Science, Philadelphia, Pennsylvania, USA
    Ann N Y Acad Sci 1098:429-36. 2007
    ..The microfluidic chip hosts a fluidic network for cell lysis, nucleic acid extraction and isolation, PCR, and labeling of the PCR product with bioconjugated, upconverting phosphor particles for detection on the lateral flow strip...
  56. ncbi Role of arthropod saliva in blood feeding: sialome and post-sialome perspectives
    Jose M C Ribeiro
    Medical Entomology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 4 Center Drive, Bethesda, Maryland, 20892 0425, USA
    Annu Rev Entomol 48:73-88. 2003
    ....
  57. pmc HSV-1 DNA in tears and saliva of normal adults
    Herbert E Kaufman
    Department of Ophthalmology, LSU Eye Center, New Orleans, LA 70112, USA
    Invest Ophthalmol Vis Sci 46:241-7. 2005
    To assess the frequency of shedding of herpes simplex virus type 1 (HSV-1) DNA in tears and saliva of asymptomatic individuals.
  58. ncbi Determinants of the diurnal course of salivary alpha-amylase
    Urs M Nater
    Emory University School of Medicine, Atlanta, GA 30322, USA
    Psychoneuroendocrinology 32:392-401. 2007
    ..Less is known about other determinants of salivary alpha-amylase activation. The objective of the current study was to describe the diurnal pattern of salivary amylase and its determinants...
  59. pmc Using recombinant proteins from Lutzomyia longipalpis saliva to estimate human vector exposure in visceral Leishmaniasis endemic areas
    Ana Paula Souza
    Centro de Pesquisas Goncalo Moniz, Fundação Oswaldo Cruz FIOCRUZ, Salvador, Brazil
    PLoS Negl Trop Dis 4:e649. 2010
    Leishmania is transmitted by female sand flies and deposited together with saliva, which contains a vast repertoire of pharmacologically active molecules that contribute to the establishment of the infection...
  60. pmc The salivary microbiota as a diagnostic indicator of oral cancer: a descriptive, non-randomized study of cancer-free and oral squamous cell carcinoma subjects
    D L Mager
    The Forsyth Institute, 140 The Fenway, Boston, MA, USA
    J Transl Med 3:27. 2005
    ..The purpose of the present investigation was to determine if the salivary counts of 40 common oral bacteria in subjects with an oral squamous cell carcinoma (OSCC) lesion would differ from those found in cancer-free (OSCC-free) controls...
  61. doi Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge
    Brigitte M Kudielka
    Jacobs Center on Lifelong Learning and Institutional Development, Jacobs University Bremen, Campus Ring 1, 28759 Bremen, Germany
    Psychoneuroendocrinology 34:2-18. 2009
    ....
  62. ncbi A PCR-DGGE method for detection and identification of Campylobacter, Helicobacter, Arcobacter and related Epsilobacteria and its application to saliva samples from humans and domestic pets
    R F Petersen
    National Food Institute, Technical University of Denmark, Søborg, Denmark
    J Appl Microbiol 103:2601-15. 2007
    ..electrophoresis (PCR-DGGE) method for the detection and identification of Campylobacter, Helicobacter and Arcobacter species (Epsilobacteria) in clinical samples and evaluate its efficacy on saliva samples from humans and domestic pets.
  63. pmc Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay
    Nicholas J Haley
    Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA
    PLoS ONE 4:e4848. 2009
    ..Here we report the presence of infectious prions in the urine and saliva of deer with chronic wasting disease (CWD)...
  64. ncbi Detection of trypanosome-specific antibodies in saliva, towards non-invasive serological diagnosis of sleeping sickness
    V Lejon
    Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium
    Trop Med Int Health 11:620-7. 2006
    The detection of trypanosome-specific antibodies in saliva is technically feasible, and, if clinically validated, could become an attractive option for non-invasive diagnosis of sleeping sickness...
  65. ncbi A high molecular mass cranberry constituent reduces mutans streptococci level in saliva and inhibits in vitro adhesion to hydroxyapatite
    Ervin I Weiss
    Department of Prosthodontics, Faculty of Dentistry, Hebrew University Hadassah, Jerusalem, Israel
    FEMS Microbiol Lett 232:89-92. 2004
    ..In vitro, the cranberry constituent inhibited the adhesion of Streptococcus sobrinus to saliva-coated hydroxyapatite...
  66. doi Trends in and predictors of second-hand smoke exposure indexed by cotinine in children in England from 1996 to 2006
    Michelle Sims
    School for Health, University of Bath, Bath BA2 7AY, UK
    Addiction 105:543-53. 2010
    ..To explore trends in and predictors of second-hand smoke (SHS) exposure in children. To identify whether inequalities in SHS exposure are changing over time...
  67. pmc Salivating for knowledge: potential pharmacological agents in tick saliva
    Joppe W R Hovius
    Center for Experimental and Molecular Medicine, Department of Internal Medicine, University of Amsterdam, Academic Medical Center, Amsterdam, The Netherlands
    PLoS Med 5:e43. 2008
  68. ncbi Effect of psychological stress on the salivary cortisol and amylase levels in healthy young adults
    Noriyasu Takai
    Department of Physiology, Osaka Dental University, 8 1, Kuzuha hanazono cho, Hirakata, Osaka 573 1121, Japan
    Arch Oral Biol 49:963-8. 2004
    b>Saliva sampling has the advantage that it is non-invasive, making multiple sampling easy and stress free...
  69. ncbi Increased cortisol bioavailability, abdominal obesity, and the metabolic syndrome in obese women
    Martine Duclos
    Laboratoire Neurogenetique et Stress, INSERM U471, Institut Francois Magendie, Universite Bordeaux II, rue C Saint Saëns, 33077 Bordeaux Cedex, France
    Obes Res 13:1157-66. 2005
    ..This study was conducted to obtain a detailed profile of hypothalamo-pituitary-adrenal (HPA) axis activity and reactivity and its differential relationships with body fat distribution and total fat mass in premenopausal obese women...
  70. ncbi A review of saliva: normal composition, flow, and function
    S P Humphrey
    Department of Oral Health Practice, College of Dentistry, University of Kentucky, Chandler Medical Center, Lexington, KY 40536 0297, USA
    J Prosthet Dent 85:162-9. 2001
    An adequate supply of saliva is critical to the preservation and maintenance of oral tissue. Clinicians often do not value the many benefits of saliva until quantities are decreased...
  71. ncbi Prenatal anxiety predicts individual differences in cortisol in pre-adolescent children
    Thomas G O'Connor
    Department of Psychiatry, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, NY 14642, USA
    Biol Psychiatry 58:211-7. 2005
    ..This study examined the long-term association between prenatal anxiety and measures of diurnal cortisol at age 10 years...
  72. pmc Salivary transcriptomic biomarkers for detection of resectable pancreatic cancer
    Lei Zhang
    School of Dentistry and Dental Research Institute, University of California Los Angeles, Los Angeles, California 90095, USA
    Gastroenterology 138:949-57.e1-7. 2010
    ....
  73. ncbi Characterization of the differentiated antioxidant profile of human saliva
    Rafael M Nagler
    Department of Oral and Maxillofacial Surgery, Oral Biochemistry Laboratory and Salivary Clinic, Rambam Medical Center, Haifa, Israel
    Free Radic Biol Med 32:268-77. 2002
    b>Saliva is armed with various defense mechanisms, such as the immunological and enzymatic defense systems...
  74. doi Intranasal oxytocin administration is reflected in human saliva
    Omri Weisman
    Department of Psychology and the Gonda Brain Sciences Center, Bar Ilan University, Ramat Gan 52900, Israel
    Psychoneuroendocrinology 37:1582-6. 2012
    ..3 pg/ml), and did not return to baseline by 4h. Results contribute to discussion on brain-periphery coordination of OT and highlight the need for further research on the temporal dynamics and durations of OT administration effects...
  75. doi Salivary stress markers, stress, and periodontitis: a pilot study
    Balwant Rai
    Oral Imaging Center, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Leuven, Belgium
    J Periodontol 82:287-92. 2011
    ..The present study is planned to explore the associations among periodontal disease, psychologic factors, and salivary markers of stress, psychoneuroimmunologic variables, and health behaviors...
  76. doi Lutzomyia longipalpis saliva drives apoptosis and enhances parasite burden in neutrophils
    Deboraci Brito Prates
    Centro de Pesquisa Goncalo Moniz Fundacao Oswaldo Cruz, Salvador, Brazil
    J Leukoc Biol 90:575-82. 2011
    ..Leishmania parasites are inoculated alongside vectors' saliva, which is a rich source of pharmacologically active substances that interfere with host immune response...
  77. pmc Mosquito saliva causes enhancement of West Nile virus infection in mice
    Linda M Styer
    New York State Department of Health, Wadsworth Center, Albany, New York 12201, USA
    J Virol 85:1517-27. 2011
    ..of mice with WNV mixed with salivary gland extract (SGE) led to higher viremia, demonstrating that mosquito saliva is the major cause of mosquito-induced enhancement...
  78. pmc Detection of dengue virus in saliva and urine by real time RT-PCR
    Telma R Poloni
    Departamento de Analises Clinicas, Toxicologicas e Bromatologicas, Faculdade de Ciencias Farmaceuticas, Universidade de Sao Paulo, Ribeirão Preto14040 903, Sao Paulo, Brasil
    Virol J 7:22. 2010
    ..The objective of this study was to analyze the usefulness of urine and saliva samples for early diagnosis of DENV infection by real time RT-PCR...
  79. doi Acute psychological stress reduces working memory-related activity in the dorsolateral prefrontal cortex
    Shaozheng Qin
    Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    Biol Psychiatry 66:25-32. 2009
    ..However, it remains unknown whether acute stress has immediate effects on WM-related prefrontal activity...
  80. pmc Early childhood stress is associated with elevated antibody levels to herpes simplex virus type 1
    Elizabeth A Shirtcliff
    Department of Psychology, University of New Orleans, 2006 Geology Psychology Building, New Orleans, LA 70148, USA
    Proc Natl Acad Sci U S A 106:2963-7. 2009
    ....
  81. pmc Lack of protection of pre-immunization with saliva of long-term colonized Phlebotomus papatasi against experimental challenge with Leishmania major and saliva of wild-caught P. papatasi
    Sami Ben Hadj Ahmed
    Laboratory of Vector Ecology, Laboratory of Epidemiology and Ecology of Parasites, and Laboratory of Immuno Pathology, Vaccinology, and Molecular Genetics, Institut Pasteur de Tunis, Tunis, Tunisia
    Am J Trop Med Hyg 83:512-4. 2010
    Immunity to saliva of Phlebotomus papatasi protects against Leishmania major infection as determined by co-inoculation of parasites with salivary gland homogenates (SGHs) of this vector...
  82. ncbi Antibodies from dogs with canine visceral leishmaniasis recognise two proteins from the saliva of Lutzomyia longipalpis
    Diana Bahia
    Laboratório de Parasitologia Celular e Molecular, Centro de Pesquisas Rene Rachou, Fundacao Oswaldo Cruz, Belo Horizonte, Minas Gerais, Brazil
    Parasitol Res 100:449-54. 2007
    The saliva of the sand fly Lutzomyia longipalpis, a major vector of Leishmania, exhibits pharmacological and immunomodulatory activities that may facilitate entry and establishment of parasites into the vertebrate host...
  83. ncbi Salivary flow patterns and the health of hard and soft oral tissues
    Colin Dawes
    Department of Oral Biology, Faculty of Dentistry, University of Manitoba, 780 Bannatyne Avenue, Winnipeg, Manitoba, Canada
    J Am Dent Assoc 139:18S-24S. 2008
    This nonsystematic review summarizes the effects of saliva on some of the diseases affecting the hard and soft oral tissues.
  84. doi Salivary cortisol responses to mental stress are associated with coronary artery calcification in healthy men and women
    Mark Hamer
    Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Eur Heart J 31:424-9. 2010
    ..We examined the cross-sectional association between the cortisol response to laboratory-induced mental stress and a marker of sub-clinical coronary atherosclerosis...
  85. doi Dynamics of the salivary gland hypertrophy virus in laboratory colonies of Glossina pallidipes (Diptera: Glossinidae)
    Adly M M Abd-Alla
    Insect Pest Control Laboratory, Joint FAO IAEA Programme of Nuclear Techniques in Food and Agriculture, Vienna, Austria
    Virus Res 150:103-10. 2010
    ..The virus is excreted in the saliva and there is a strong correlation between the infection status (negative, slight or strong by PCR) and the numbers ..
  86. doi Effects of exogenous testosterone on the ventral striatal BOLD response during reward anticipation in healthy women
    Erno J Hermans
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    Neuroimage 52:277-83. 2010
    ..By showing a potential mechanism underlying central reinforcement of androgen use, the present findings may moreover have implications for our understanding of the pathophysiology of AAS dependency...
  87. ncbi Do salivary antibodies reliably reflect both mucosal and systemic immunity?
    Per Brandtzaeg
    Laboratory for Immunohistochemistry and Immunopathology, Department and Institute of Pathology, University of Oslo, Rikshospitalet Radiumhospitalet Medical Center, Norway
    Ann N Y Acad Sci 1098:288-311. 2007
    Two major antibody classes operate in saliva: secretory IgA (SIgA) and IgG. The former is synthesized as dimeric IgA by plasma cells (PCs) in salivary glands and is exported by the polymeric Ig receptor (pIgR)...
  88. pmc The relative importance of family socioeconomic status and school-based peer hierarchies for morning cortisol in youth: an exporatory study
    Patrick West
    MRC Social and Public Health Sciences Unit, 4, Lilybank Gardens, Glasgow G12 8RZ, UK
    Soc Sci Med 70:1246-53. 2010
    ..Overall, the results highlight the greater importance of school-based peer groups than family SES for young people's psychoneuroendocrine response...
  89. doi Polymorphisms of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 and the blood and salivary ethanol and acetaldehyde concentrations of Japanese alcoholic men
    Akira Yokoyama
    National Hospital Organization Kurihama Alcoholism Center, Yokosuka, Kanagawa, Japan
    Alcohol Clin Exp Res 34:1246-56. 2010
    ....
  90. pmc Lutzomyia longipalpis saliva or salivary protein LJM19 protects against Leishmania braziliensis and the saliva of its vector, Lutzomyia intermedia
    Natalia M Tavares
    Centro de Pesquisa Gonçalo Moniz, FIOCRUZ, Salvador, Bahia, Brazil
    PLoS Negl Trop Dis 5:e1169. 2011
    Leishmania transmission occurs in the presence of insect saliva. Immunity to Phlebotomus papatasi or Lutzomyia longipalpis saliva or salivary components confers protection against an infection by Leishmania in the presence of the ..
  91. pmc Immunity to Lutzomyia intermedia saliva modulates the inflammatory environment induced by Leishmania braziliensis
    Tatiana R de Moura
    Centro de Pesquisas Goncalo Moniz, Fundação Oswaldo Cruz FIOCRUZ, Salvador, Brazil
    PLoS Negl Trop Dis 4:e712. 2010
    During blood feeding, sand flies inject Leishmania parasites in the presence of saliva. The types and functions of cells present at the first host-parasite contact are critical to the outcome on infection and sand fly saliva has been ..
  92. doi Impact of stressors in a natural context on release of cortisol in healthy adult humans: a meta-analysis
    Kathy Michaud
    Department of Psychology, Carleton University, Ottawa, Ont, Canada
    Stress 11:177-97. 2008
    ..Nevertheless, there are ample data suggesting that stressful events, through their actions on cortisol levels and reactivity, may influence psychological and physical pathology...
  93. ncbi Human glandular salivas: their separate collection and analysis
    E C Veerman
    Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam ACTA, Vrije Universiteit, The Netherlands
    Eur J Oral Sci 104:346-52. 1996
    Human saliva is secreted by the three pairs of major salivary glands (parotid, submandibular, and sublingual), and numerous minor ones, e.g. labial, buccal and (glosso)palatine glands...
  94. doi Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies
    Melanie Bahlo
    The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Victoria, Australia
    Cancer Epidemiol Biomarkers Prev 19:794-8. 2010
    ..performed a multiple sclerosis (MS) GWAS where a substantial component of the cases (24%) had DNA derived from saliva. Genotyping was done on the Illumina genotyping platform using the Infinium Hap370CNV DUO microarray...
  95. ncbi Poor dental status increases acetaldehyde production from ethanol in saliva: a possible link to increased oral cancer risk among heavy drinkers
    N Homann
    Research Unit of Alcohol Diseases, Helsinki University Central Hospital, Helsinki, Finland
    Oral Oncol 37:153-8. 2001
    ..was conducted to evaluate the role of dental status on the microbial production of acetaldehyde from ethanol in saliva. The microbial acetaldehyde production from ethanol was related to the dental score in 132 volunteers...
  96. pmc Tropheryma whipplei in patients with pneumonia
    Sabri Bousbia
    CNRS IRD Faculte de Medecine, Marseille, France
    Emerg Infect Dis 16:258-63. 2010
    ..PCR-based methods for diagnosis of WD have been developed. T. whipplei has been identified in saliva and stool samples from patients with WD and from healthy persons. T...
  97. ncbi Proteins in the saliva of the Ixodida (ticks): pharmacological features and biological significance
    N A Steen
    Institute for Molecular Bioscience, University of Queensland, Brisbane, 4072, Australia
    Toxicon 47:1-20. 2006
    The saliva of ticks (Suborder Ixodida) is critical to their survival as parasites...
  98. ncbi Saliva specimen: a new laboratory tool for diagnostic and basic investigation
    Silvia Chiappin
    Section of Clinical Biochemistry, Department of Medical Diagnostic Sciences and Spec Ther, University of Padua, c o ex Istituto di Semeiotica Medica, Via Ospedale 105 35128, Padova, Italy
    Clin Chim Acta 383:30-40. 2007
    The assay of saliva is an increasing area of research with implications for basic and clinical purposes...
  99. pmc The StcE protease contributes to intimate adherence of enterohemorrhagic Escherichia coli O157:H7 to host cells
    Thomas E Grys
    Department of Medical Microbiology and Immunology, University of Wisconsin Madison, 1300 University Ave, Room 481 MSC, Madison, WI 53706, USA
    Infect Immun 73:1295-303. 2005
    ..two new substrates for StcE, mucin 7 and glycoprotein 340, and that purified StcE reduces the viscosity of human saliva. We tested the hypothesis that StcE contributes to intimate adherence of EHEC to host cells by cleavage of ..
  100. pmc Insight into the sialome of the castor bean tick, Ixodes ricinus
    Jindrich Chmelar
    Faculty of Science, University of South Bohemia, Ceske Budejovice, Czech Republic
    BMC Genomics 9:233. 2008
    ..Here, we focused on the sialome of the European vector of Lyme disease, Ixodes ricinus...
  101. ncbi Biofilm formation of Candida albicans is variably affected by saliva and dietary sugars
    Ye Jin
    Faculty of Dentistry, The University of Hong Kong, Oral Biosciences, 5 F, Prince Philip Dental Hospital 34, Hong Kong, Hong Kong
    Arch Oral Biol 49:789-98. 2004
    ..Therefore we examined the effect of human whole saliva and dietary sugars, glucose and galactose on the adhesion and biofilm formation of Candida albicans. Biofilms of C...

Research Grants79

  1. NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINS
    Frances Walker; Fiscal Year: 2009
    The saliva of the blood-sucking insect, Rhodnius prolixus, originally from the Amazon river basin, which carries the parasite Trypanasoma cruzi, the vector of Chagas' disease, contains a suite of heme proteins that we have named ..
  2. NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINS
    Frances Walker; Fiscal Year: 2009
    The saliva of the blood-sucking insect, Rhodnius prolixus, originally from the Amazon river basin, which carries the parasite Trypanasoma cruzi, the vector of Chagas' disease, contains a suite of heme proteins that we have named ..
  3. Influence of Genetics and Air Pollution Exposures on Birth Outcomes
    Kathleen Mortimer; Fiscal Year: 2007
    ..as low birth weight and premature birth, and (b) evaluate the feasibility of assembling a birth-cohort to provide saliva samples for the analysis of genetic susceptibility to the effects of air pollution on birth outcomes...
  4. The role of sand fly saliva in visceralization of Leishmania parasites
    Gregory Lanzaro; Fiscal Year: 2009
    It is well known that substances in the saliva of Phlebotomine sand flies enhance pathogenesis of leishmanial parasites in their mammalian hosts and exacerbates the pathology these parasites produce...
  5. The role of sand fly saliva in visceralization of Leishmania parasites.
    Gregory Lanzaro; Fiscal Year: 2007
    It is well known that substances in the saliva of Phlebotomine sand flies enhance pathogenesis of leishmanial parasites in their mammalian hosts and exacerbates the pathology these parasites produce...
  6. NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINS
    Frances Walker; Fiscal Year: 2006
    We have discovered a series of heme proteins in the saliva of the blood-sucking bug Rhodnius prolixus that act as vasodilators, anti-platelet aggregation and anti-histaminic agents when injected into the victim...
  7. NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINS
    FRANCES ANN WALKER; Fiscal Year: 2010
    The saliva of the blood-sucking insect, Rhodnius prolixus, originally from the Amazon river basin, which carries the parasite Trypanasoma cruzi, the vector of Chagas'disease, contains a suite of heme proteins that we have named ..
  8. SALIVARY IMMUNE RESPONSE TO COMMENSAL ORAL BACTERIA
    Michael Cole; Fiscal Year: 1993
    ..Secretory immunoglobulin A (SigA) antibodies reactive with commensal bacteria are present in saliva but their impact ont he normal flora is not known...
  9. REGULATION OF IMMUNE RESPONSE IN THE ORAL CAVITY
    Suzanne Michalek; Fiscal Year: 2003
    ..g., teeth. Secretory IgA antibodies in saliva are important in protection against oral diseases, including Streptococcus mutans-induced dental caries, and are ..
  10. DEFINING PRIMARY HHV-6 AND HHV7 INFECTIONS IN CHILDREN
    Danielle Zerr; Fiscal Year: 2003
    ..Data from symptom diaries will be correlated with primary infection as defined by onset of the viruses in saliva. Documentation of seroconversion is the current gold standard for diagnosis of HHV-6 infection, but by definition, ..
  11. IN VIVO STUDIES OF SALIVA ANTIMICROBIAL PROTEINS
    JOEL RUDNEY; Fiscal Year: 2001
    ..In vitro studies have identified saliva proteins involved in each process...
  12. [Ca2+]i and Secretory Dynamics in Parotid Acinar Cells
    David Yule; Fiscal Year: 2007
    b>Saliva is vital for oral health. It is essential for the hydration of the oral mucosa; it provides lubrication, begins nutrient digestion and imparts antimicrobial and mechanical protection for the mouth and upper gastrointestinal tract...
  13. PMCA Detection of CWD Infection in Cervid and Non-Cervid Species
    EDWARD ARTHUR HOOVER; Fiscal Year: 2010
    ..We have found that infectious prions capable of transmitting CWD are present in the saliva, blood, and urine of CWD-infected deer, potentially explaining the lateral transmission of the disease...
  14. Intra-Oral Biofilm Formation
    Sigmund Socransky; Fiscal Year: 2004
    ..Two important bulk fluids, saliva and GCF, bathe the biofilm surfaces and play and undetermined role in biofilm development...
  15. ORAL MUCOSA MICROBIOTA IN HEALTH, CANCER & MUCOSITIS
    Donna Mager; Fiscal Year: 2004
    ..To compare the microbial composition of samples from 8 different oral mucous membrane sites with that found in saliva, supra and sub-gingival plaque in subjects stratified according to periodontal status (health or disease) and ..
  16. Demographic Analysis of Healthy Longevity in China
    Yi Zeng; Fiscal Year: 2009
    ..We plan to collect saliva DNA using Oragene tool kits from voluntary participants among 15,409 interviewees in the sample of about 937 ..