saliva

Summary

Summary: The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin.

Top Publications

  1. ncbi Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research
    Sally S Dickerson
    Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA
    Psychol Bull 130:355-91. 2004
  2. ncbi Exosomes from human saliva as a source of microRNA biomarkers
    A Michael
    Sjögren s Syndrome Clinic, Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, Bethesda, MD 20892, USA
    Oral Dis 16:34-8. 2010
  3. ncbi Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change
    Jens C Pruessner
    McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada
    Psychoneuroendocrinology 28:916-31. 2003
  4. ncbi The role of saliva in tick feeding
    Ivo M B Francischetti
    Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda MD, USA
    Front Biosci 14:2051-88. 2009
  5. ncbi Pyrosequencing analysis of the oral microflora of healthy adults
    B J F Keijser
    TNO Quality of Life, Business Unit Food and Biotechnology Innovations, Microbial Genomics Group, Zeist, The Netherlands
    J Dent Res 87:1016-20. 2008
  6. ncbi Study of inter- and intra-individual variations in the salivary microbiota
    Vladimir Lazarevic
    Genomic Research Laboratory, Geneva University Hospitals, Rue Gabrielle Perret Gentil 4, CH 1211 Geneva 14, Switzerland
    BMC Genomics 11:523. 2010
  7. ncbi Global diversity in the human salivary microbiome
    Ivan Nasidze
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Genome Res 19:636-43. 2009
  8. ncbi Diagnosis of dengue virus infection by detection of specific immunoglobulin M (IgM) and IgA antibodies in serum and saliva
    Angel Balmaseda
    National Center for Diagnosis and Reference, Ministry of Health, Granada, Nicaragua
    Clin Diagn Lab Immunol 10:317-22. 2003
  9. ncbi Human antibody response to Anopheles gambiae saliva: an immuno-epidemiological biomarker to evaluate the efficacy of insecticide-treated nets in malaria vector control
    Papa M Drame
    Institut de recherche pour le developpement IRD, UR024 Epidémiologie et Prévention Unit, Dakar, Senegal
    Am J Trop Med Hyg 83:115-21. 2010
  10. ncbi Characterization of the antibody response to the saliva of Phlebotomus papatasi in people living in endemic areas of cutaneous leishmaniasis
    Soumaya Marzouki
    Department of Clinical Immunology, Institut Pasteur de Tunis, 13 Place Pasteur, Le Belvedere, Tunisia
    Am J Trop Med Hyg 84:653-61. 2011

Detail Information

Publications310 found, 100 shown here

  1. ncbi Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research
    Sally S Dickerson
    Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA
    Psychol Bull 130:355-91. 2004
    ..These findings are consistent with the animal literature on the physiological effects of uncontrollable social threat and contradict the belief that cortisol is responsive to all types of stressors...
  2. ncbi Exosomes from human saliva as a source of microRNA biomarkers
    A Michael
    Sjögren s Syndrome Clinic, Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, Bethesda, MD 20892, USA
    Oral Dis 16:34-8. 2010
    The aim of this study was to examine the presence of microRNAs (miRNAs) within exosomes isolated from human saliva and to optimize and test methods for successful downstream applications.
  3. ncbi Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change
    Jens C Pruessner
    McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada
    Psychoneuroendocrinology 28:916-31. 2003
    ..It is shown that depending on which formula is used, different associations with other variables may emerge. Consequently, it is recommended to employ both formulas when analyzing data sets with repeated measures...
  4. ncbi The role of saliva in tick feeding
    Ivo M B Francischetti
    Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda MD, USA
    Front Biosci 14:2051-88. 2009
    ..This supplemental file is accessble fromhttp://exon.niaid.nih.gov/transcriptome/tick_review/Sup-Table-1.xls.gz...
  5. ncbi Pyrosequencing analysis of the oral microflora of healthy adults
    B J F Keijser
    TNO Quality of Life, Business Unit Food and Biotechnology Innovations, Microbial Genomics Group, Zeist, The Netherlands
    J Dent Res 87:1016-20. 2008
    ..We hypothesized that the species richness of human oral microflora is underestimated. Saliva and supragingival plaque were sampled from 71 and 98 healthy adults, respectively...
  6. ncbi Study of inter- and intra-individual variations in the salivary microbiota
    Vladimir Lazarevic
    Genomic Research Laboratory, Geneva University Hospitals, Rue Gabrielle Perret Gentil 4, CH 1211 Geneva 14, Switzerland
    BMC Genomics 11:523. 2010
    ..Culture-independent approaches provide the best means to assess the diversity of oral bacteria because most of them remain uncultivable...
  7. ncbi Global diversity in the human salivary microbiome
    Ivan Nasidze
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Genome Res 19:636-43. 2009
    ..We analyzed 14,115 partial ( approximately 500 bp) 16S ribosomal RNA (rRNA) sequences from saliva samples from 120 healthy individuals (10 individuals from each of 12 worldwide locations)...
  8. ncbi Diagnosis of dengue virus infection by detection of specific immunoglobulin M (IgM) and IgA antibodies in serum and saliva
    Angel Balmaseda
    National Center for Diagnosis and Reference, Ministry of Health, Granada, Nicaragua
    Clin Diagn Lab Immunol 10:317-22. 2003
    ..dengue virus (DEN) infection, the detection of DEN-specific immunoglobulin M (IgM) and IgA antibodies in serum and saliva specimens was assessed in 147 patients with symptoms of DEN infection seen at the Ministry of Health in Nicaragua...
  9. ncbi Human antibody response to Anopheles gambiae saliva: an immuno-epidemiological biomarker to evaluate the efficacy of insecticide-treated nets in malaria vector control
    Papa M Drame
    Institut de recherche pour le developpement IRD, UR024 Epidémiologie et Prévention Unit, Dakar, Senegal
    Am J Trop Med Hyg 83:115-21. 2010
    ..This study investigates a potential immunological marker, based on human antibody responses to Anopheles saliva, as a new indicator to evaluate the efficacy of insecticide-treated nets (ITNs)...
  10. ncbi Characterization of the antibody response to the saliva of Phlebotomus papatasi in people living in endemic areas of cutaneous leishmaniasis
    Soumaya Marzouki
    Department of Clinical Immunology, Institut Pasteur de Tunis, 13 Place Pasteur, Le Belvedere, Tunisia
    Am J Trop Med Hyg 84:653-61. 2011
    Important data obtained in mice raise the possibility that immunization against the saliva of sand flies could protect from leishmaniasis...
  11. ncbi Influence of cranberry proanthocyanidins on formation of biofilms by Streptococcus mutans on saliva-coated apatitic surface and on dental caries development in vivo
    H Koo
    Eastman Department of Dentistry, University of Rochester Medical Center, Rochester, NY 14620, USA hyun_koo urmc rochester edu
    Caries Res 44:116-26. 2010
    ..mutans biofilm formation on saliva-coated hydroxyapatite surface, and on dental caries development in Sprague-Dawley rats...
  12. ncbi Smoke-free homes in England: prevalence, trends and validation by cotinine in children
    M J Jarvis
    Health Behaviour Research Centre, Department of Epidemiology and Public Health, University College London, London, UK
    Tob Control 18:491-5. 2009
    ..Main outcome measures were cotinine measured in saliva, smoke-free homes defined by "no" response to "Does anyone smoke inside this house/flat on most ..
  13. ncbi Measurement of recent exposure to Phlebotomus argentipes, the vector of Indian visceral Leishmaniasis, by using human antibody responses to sand fly saliva
    Meredith F Clements
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Trop Med Hyg 82:801-7. 2010
    Antibody (IgG) responses to the saliva of Phlebotomus argentipes were investigated using serum samples from regions of India endemic and non-endemic for visceral leishmaniasis (VL)...
  14. ncbi Enhanced Leishmania braziliensis infection following pre-exposure to sandfly saliva
    Tatiana R de Moura
    Centro de Pesquisas Goncalo Moniz, Fundação Oswaldo Cruz FIOCRUZ, Salvador, Brazil
    PLoS Negl Trop Dis 1:e84. 2007
    Sand fly saliva has an array of pharmacological and immunomodulatory components, and immunity to saliva protects against Leishmania infection...
  15. ncbi Detection of species-specific antibody response of humans and mice bitten by sand flies
    I Rohousova
    Department of Parasitology, Faculty of Science, Charles University, Vinicna 7, 128 44 Prague 2, Czech Republic
    Parasitology 130:493-9. 2005
    Sand fly saliva plays an important role in Leishmania transmission. We characterized the host antibody response to saliva from 3 sand fly species...
  16. ncbi Evaluation of the antibody response to Anopheles salivary antigens as a potential marker of risk of malaria
    Franck Remoue
    Institut de recherche pour le developpement IRD, UR24 Epidémiologie et Prévention Unit, Centre IRD de Hann, BP 1386, Dakar, Senegal
    Trans R Soc Trop Med Hyg 100:363-70. 2006
    ..The specific antibody (Ab) IgG response to saliva obtained from Anopheles gambiae mosquitoes was evaluated in young children from an area of seasonal malaria ..
  17. ncbi The enhancement of arbovirus transmission and disease by mosquito saliva is associated with modulation of the host immune response
    Bradley S Schneider
    Institut Pasteur, Departement de Parasitologie, Unités de Réponses Précoces aux Parasites et Immunopathologie, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Trans R Soc Trop Med Hyg 102:400-8. 2008
    ..Arboviruses, including dengue and West Nile virus, are injected into vertebrates within mosquito saliva during mosquito feeding...
  18. ncbi Isolation and detection of Campylobacter concisus from saliva of healthy individuals and patients with inflammatory bowel disease
    Li Zhang
    School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, Sydney, New South Wales 2052, Australia
    J Clin Microbiol 48:2965-7. 2010
    The presence of Campylobacter concisus in the saliva of healthy individuals and patients with inflammatory bowel disease (IBD) was examined. C...
  19. ncbi Stability of salivary steroids: the influences of storage, food and dental care
    M Groschl
    Hospital for Children and Adolescents, Friedrich Alexander University, Erlangen Nurnberg, Germany
    Steroids 66:737-41. 2001
    ..b>Saliva samples of healthy adults (n = 15; m:8; f:7) were collected directly before and after dental care, and directly ..
  20. ncbi Anti-Anopheles darlingi saliva antibodies as marker of Plasmodium vivax infection and clinical immunity in the Brazilian Amazon
    Bruno Bezerril Andrade
    Centro de Pesquisas Gonçalo Moniz FIOCRUZ, Bahia, Brazil
    Malar J 8:121. 2009
    ..Thus, innovative strategies are needed to reduce disease burden. The malaria vectors, through the injection of saliva into the host skin, play important role on disease transmission and may influence malaria morbidity...
  21. ncbi Comparative analysis of human saliva microbiome diversity by barcoded pyrosequencing and cloning approaches
    Ivan Nasidze
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Anal Biochem 391:64-8. 2009
    ..with a barcoded pyrosequencing method to see whether the latter accurately describes microbiome diversity in human saliva. Our results indicate that despite the shorter read lengths, the pyrosequencing approach provides a description of ..
  22. ncbi Structure and function of a "yellow" protein from saliva of the sand fly Lutzomyia longipalpis that confers protective immunity against Leishmania major infection
    Xueqing Xu
    Laboratory of Malaria and Vector Research, NIAID, National Institutes of Health, Rockville, Maryland 20852, USA
    J Biol Chem 286:32383-93. 2011
    ..longipalpis saliva. Additionally, splenocytes of exposed mice produce IFN-γ upon stimulation with LJM11, demonstrating the systemic ..
  23. ncbi Detection of trypanosome-specific antibodies in saliva, towards non-invasive serological diagnosis of sleeping sickness
    V Lejon
    Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium
    Trop Med Int Health 11:620-7. 2006
    The detection of trypanosome-specific antibodies in saliva is technically feasible, and, if clinically validated, could become an attractive option for non-invasive diagnosis of sleeping sickness...
  24. ncbi Antibody response against saliva antigens of Anopheles gambiae and Aedes aegypti in travellers in tropical Africa
    Eve Orlandi Pradines
    Unité de recherche en biologie et en épidémiologie parasitaires, Institut de Medecine Tropicale du Service de Sante des Armees, Parc le Pharo, BP 46, 13998 Marseille Armees, France
    Microbes Infect 9:1454-62. 2007
    ..The IgM and IgG antibody responses of 88 French soldiers against the saliva of Anopheles gambiae and Aedes aegypti were evaluated before and after a 5-month journey in tropical Africa...
  25. ncbi Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay
    Nicholas J Haley
    Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA
    PLoS ONE 4:e4848. 2009
    ..Here we report the presence of infectious prions in the urine and saliva of deer with chronic wasting disease (CWD)...
  26. ncbi A high molecular mass cranberry constituent reduces mutans streptococci level in saliva and inhibits in vitro adhesion to hydroxyapatite
    Ervin I Weiss
    Department of Prosthodontics, Faculty of Dentistry, Hebrew University Hadassah, Jerusalem, Israel
    FEMS Microbiol Lett 232:89-92. 2004
    ..In vitro, the cranberry constituent inhibited the adhesion of Streptococcus sobrinus to saliva-coated hydroxyapatite...
  27. ncbi Salivary transcriptomic biomarkers for detection of resectable pancreatic cancer
    Lei Zhang
    School of Dentistry and Dental Research Institute, University of California Los Angeles, Los Angeles, California 90095, USA
    Gastroenterology 138:949-57.e1-7. 2010
    ....
  28. ncbi Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma
    Andre Lopes Carvalho
    Department of Otolaryngology Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 0910, USA
    Clin Cancer Res 14:97-107. 2008
    ..To evaluate aberrant promoter hypermethylation of candidate tumor suppressor genes as a means to detect epigenetic alterations specific to solid tumors, including head and neck squamous cell carcinoma (HNSCC)...
  29. ncbi Prenatal anxiety predicts individual differences in cortisol in pre-adolescent children
    Thomas G O'Connor
    Department of Psychiatry, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, NY 14642, USA
    Biol Psychiatry 58:211-7. 2005
    ..This study examined the long-term association between prenatal anxiety and measures of diurnal cortisol at age 10 years...
  30. ncbi Using recombinant proteins from Lutzomyia longipalpis saliva to estimate human vector exposure in visceral Leishmaniasis endemic areas
    Ana Paula Souza
    Centro de Pesquisas Goncalo Moniz, Fundação Oswaldo Cruz FIOCRUZ, Salvador, Brazil
    PLoS Negl Trop Dis 4:e649. 2010
    Leishmania is transmitted by female sand flies and deposited together with saliva, which contains a vast repertoire of pharmacologically active molecules that contribute to the establishment of the infection...
  31. ncbi Nanostructural and transcriptomic analyses of human saliva derived exosomes
    VISWANATHAN PALANISAMY
    Department of Craniofacial Biology, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America
    PLoS ONE 5:e8577. 2010
    ..They are ubiquitous in most body fluids (breast milk, saliva, blood, urine, malignant ascites, amniotic, bronchoalveolar lavage, and synovial fluids)...
  32. ncbi Analysis of oral microbiota in children with dental caries by PCR-DGGE and barcoded pyrosequencing
    Zongxin Ling
    State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China
    Microb Ecol 60:677-90. 2010
    ..and PCR-denaturing gradient gel electrophoresis (DGGE) to examine bacterial diversity of oral microbiota in saliva and supragingival plaques from 60 children aged 3 to 6 years old with and without dental caries from China...
  33. ncbi Salivary flow patterns and the health of hard and soft oral tissues
    Colin Dawes
    Department of Oral Biology, Faculty of Dentistry, University of Manitoba, 780 Bannatyne Avenue, Winnipeg, Manitoba, Canada
    J Am Dent Assoc 139:18S-24S. 2008
    This nonsystematic review summarizes the effects of saliva on some of the diseases affecting the hard and soft oral tissues.
  34. ncbi Early childhood stress is associated with elevated antibody levels to herpes simplex virus type 1
    Elizabeth A Shirtcliff
    Department of Psychology, University of New Orleans, 2006 Geology Psychology Building, New Orleans, LA 70148, USA
    Proc Natl Acad Sci U S A 106:2963-7. 2009
    ....
  35. ncbi Salivary cortisol responses to mental stress are associated with coronary artery calcification in healthy men and women
    Mark Hamer
    Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Eur Heart J 31:424-9. 2010
    ..We examined the cross-sectional association between the cortisol response to laboratory-induced mental stress and a marker of sub-clinical coronary atherosclerosis...
  36. ncbi Assessing salivary cortisol in large-scale, epidemiological research
    Emma K Adam
    School of Education and Social Policy and Institute for Policy Research, Northwestern University, United States
    Psychoneuroendocrinology 34:1423-36. 2009
    ....
  37. ncbi Acute psychological stress reduces working memory-related activity in the dorsolateral prefrontal cortex
    Shaozheng Qin
    Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    Biol Psychiatry 66:25-32. 2009
    ..However, it remains unknown whether acute stress has immediate effects on WM-related prefrontal activity...
  38. ncbi Antibodies from dogs with canine visceral leishmaniasis recognise two proteins from the saliva of Lutzomyia longipalpis
    Diana Bahia
    Laboratório de Parasitologia Celular e Molecular, Centro de Pesquisas Rene Rachou, Fundacao Oswaldo Cruz, Belo Horizonte, Minas Gerais, Brazil
    Parasitol Res 100:449-54. 2007
    The saliva of the sand fly Lutzomyia longipalpis, a major vector of Leishmania, exhibits pharmacological and immunomodulatory activities that may facilitate entry and establishment of parasites into the vertebrate host...
  39. ncbi Polymorphisms of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 and the blood and salivary ethanol and acetaldehyde concentrations of Japanese alcoholic men
    Akira Yokoyama
    National Hospital Organization Kurihama Alcoholism Center, Yokosuka, Kanagawa, Japan
    Alcohol Clin Exp Res 34:1246-56. 2010
    ....
  40. ncbi Lack of protection of pre-immunization with saliva of long-term colonized Phlebotomus papatasi against experimental challenge with Leishmania major and saliva of wild-caught P. papatasi
    Sami Ben Hadj Ahmed
    Laboratory of Vector Ecology, Laboratory of Epidemiology and Ecology of Parasites, and Laboratory of Immuno Pathology, Vaccinology, and Molecular Genetics, Institut Pasteur de Tunis, Tunis, Tunisia
    Am J Trop Med Hyg 83:512-4. 2010
    Immunity to saliva of Phlebotomus papatasi protects against Leishmania major infection as determined by co-inoculation of parasites with salivary gland homogenates (SGHs) of this vector...
  41. ncbi Mosquito saliva causes enhancement of West Nile virus infection in mice
    Linda M Styer
    New York State Department of Health, Wadsworth Center, Albany, New York 12201, USA
    J Virol 85:1517-27. 2011
    ..of mice with WNV mixed with salivary gland extract (SGE) led to higher viremia, demonstrating that mosquito saliva is the major cause of mosquito-induced enhancement...
  42. ncbi Dynamics of the salivary gland hypertrophy virus in laboratory colonies of Glossina pallidipes (Diptera: Glossinidae)
    Adly M M Abd-Alla
    Insect Pest Control Laboratory, Joint FAO IAEA Programme of Nuclear Techniques in Food and Agriculture, Vienna, Austria
    Virus Res 150:103-10. 2010
    ..The virus is excreted in the saliva and there is a strong correlation between the infection status (negative, slight or strong by PCR) and the numbers ..
  43. ncbi Immunity to Lutzomyia intermedia saliva modulates the inflammatory environment induced by Leishmania braziliensis
    Tatiana R de Moura
    Centro de Pesquisas Goncalo Moniz, Fundação Oswaldo Cruz FIOCRUZ, Salvador, Brazil
    PLoS Negl Trop Dis 4:e712. 2010
    During blood feeding, sand flies inject Leishmania parasites in the presence of saliva. The types and functions of cells present at the first host-parasite contact are critical to the outcome on infection and sand fly saliva has been ..
  44. ncbi Do salivary antibodies reliably reflect both mucosal and systemic immunity?
    Per Brandtzaeg
    Laboratory for Immunohistochemistry and Immunopathology, Department and Institute of Pathology, University of Oslo, Rikshospitalet Radiumhospitalet Medical Center, Norway
    Ann N Y Acad Sci 1098:288-311. 2007
    Two major antibody classes operate in saliva: secretory IgA (SIgA) and IgG. The former is synthesized as dimeric IgA by plasma cells (PCs) in salivary glands and is exported by the polymeric Ig receptor (pIgR)...
  45. ncbi The relative importance of family socioeconomic status and school-based peer hierarchies for morning cortisol in youth: an exporatory study
    Patrick West
    MRC Social and Public Health Sciences Unit, 4, Lilybank Gardens, Glasgow G12 8RZ, UK
    Soc Sci Med 70:1246-53. 2010
    ..Overall, the results highlight the greater importance of school-based peer groups than family SES for young people's psychoneuroendocrine response...
  46. ncbi Detection of dengue virus in saliva and urine by real time RT-PCR
    Telma R Poloni
    Departamento de Analises Clinicas, Toxicologicas e Bromatologicas, Faculdade de Ciencias Farmaceuticas, Universidade de Sao Paulo, Ribeirão Preto14040 903, Sao Paulo, Brasil
    Virol J 7:22. 2010
    ..The objective of this study was to analyze the usefulness of urine and saliva samples for early diagnosis of DENV infection by real time RT-PCR...
  47. ncbi Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages
    Cecilia Lässer
    Krefting Research Centre, Sahlgrenska Academy, University of Gothenburg, Box 424, 405 30 Gothenburg, Sweden
    J Transl Med 9:9. 2011
    ..Our aim was therefore to determine the presence of RNA in exosomes from human saliva, plasma and breast milk and whether these exosomes can be taken up by macrophages.
  48. ncbi Effects of exogenous testosterone on the ventral striatal BOLD response during reward anticipation in healthy women
    Erno J Hermans
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    Neuroimage 52:277-83. 2010
    ..By showing a potential mechanism underlying central reinforcement of androgen use, the present findings may moreover have implications for our understanding of the pathophysiology of AAS dependency...
  49. ncbi Lutzomyia longipalpis saliva or salivary protein LJM19 protects against Leishmania braziliensis and the saliva of its vector, Lutzomyia intermedia
    Natalia M Tavares
    Centro de Pesquisa Gonçalo Moniz, FIOCRUZ, Salvador, Bahia, Brazil
    PLoS Negl Trop Dis 5:e1169. 2011
    Leishmania transmission occurs in the presence of insect saliva. Immunity to Phlebotomus papatasi or Lutzomyia longipalpis saliva or salivary components confers protection against an infection by Leishmania in the presence of the ..
  50. ncbi A multiplex assay for the simultaneous detection of antibodies against 15 Plasmodium falciparum and Anopheles gambiae saliva antigens
    Elena Ambrosino
    IRBA and UMR6236, Marseille, France
    Malar J 9:317. 2010
    ..Thus, the aim of this study was to develop a sensitive tool to assess the exposure to malaria or to bites from the vector Anopheles gambiae, despite anti-malarial prophylactic treatment...
  51. ncbi Impact of stressors in a natural context on release of cortisol in healthy adult humans: a meta-analysis
    Kathy Michaud
    Department of Psychology, Carleton University, Ottawa, Ont, Canada
    Stress 11:177-97. 2008
    ..Nevertheless, there are ample data suggesting that stressful events, through their actions on cortisol levels and reactivity, may influence psychological and physical pathology...
  52. ncbi Saliva specimen: a new laboratory tool for diagnostic and basic investigation
    Silvia Chiappin
    Section of Clinical Biochemistry, Department of Medical Diagnostic Sciences and Spec Ther, University of Padua, c o ex Istituto di Semeiotica Medica, Via Ospedale 105 35128, Padova, Italy
    Clin Chim Acta 383:30-40. 2007
    The assay of saliva is an increasing area of research with implications for basic and clinical purposes...
  53. ncbi Tropheryma whipplei in patients with pneumonia
    Sabri Bousbia
    CNRS IRD Faculte de Medecine, Marseille, France
    Emerg Infect Dis 16:258-63. 2010
    ..PCR-based methods for diagnosis of WD have been developed. T. whipplei has been identified in saliva and stool samples from patients with WD and from healthy persons. T...
  54. ncbi Proteins in the saliva of the Ixodida (ticks): pharmacological features and biological significance
    N A Steen
    Institute for Molecular Bioscience, University of Queensland, Brisbane, 4072, Australia
    Toxicon 47:1-20. 2006
    The saliva of ticks (Suborder Ixodida) is critical to their survival as parasites...
  55. ncbi Biofilm formation of Candida albicans is variably affected by saliva and dietary sugars
    Ye Jin
    Faculty of Dentistry, The University of Hong Kong, Oral Biosciences, 5/F, Prince Philip Dental Hospital 34, Hong Kong, Hong Kong
    Arch Oral Biol 49:789-98. 2004
    ..Therefore we examined the effect of human whole saliva and dietary sugars, glucose and galactose on the adhesion and biofilm formation of Candida albicans. Biofilms of C...
  56. ncbi The StcE protease contributes to intimate adherence of enterohemorrhagic Escherichia coli O157:H7 to host cells
    Thomas E Grys
    Department of Medical Microbiology and Immunology, University of Wisconsin Madison, 1300 University Ave, Room 481 MSC, Madison, WI 53706, USA
    Infect Immun 73:1295-303. 2005
    ..two new substrates for StcE, mucin 7 and glycoprotein 340, and that purified StcE reduces the viscosity of human saliva. We tested the hypothesis that StcE contributes to intimate adherence of EHEC to host cells by cleavage of ..
  57. ncbi Human glandular salivas: their separate collection and analysis
    E C Veerman
    Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam ACTA, Vrije Universiteit, The Netherlands
    Eur J Oral Sci 104:346-52. 1996
    Human saliva is secreted by the three pairs of major salivary glands (parotid, submandibular, and sublingual), and numerous minor ones, e.g. labial, buccal and (glosso)palatine glands...
  58. ncbi Exosome-like vesicles with dipeptidyl peptidase IV in human saliva
    Yuko Ogawa
    Institute of Medicinal Chemistry, Hoshi University, Tokyo, Japan
    Biol Pharm Bull 31:1059-62. 2008
    b>Saliva contains a large number of proteins that participate in the protection of oral tissue. We found, for the first time, small vesicles (30-130 nm in diameter) in human whole saliva...
  59. ncbi Insight into the sialome of the castor bean tick, Ixodes ricinus
    Jindrich Chmelar
    Faculty of Science, University of South Bohemia, Ceske Budejovice, Czech Republic
    BMC Genomics 9:233. 2008
    ..Here, we focused on the sialome of the European vector of Lyme disease, Ixodes ricinus...
  60. ncbi Aging and salivary cytokine concentrations as predictors of whole saliva flow rates among women: a preliminary study
    Charles Streckfus
    Department of Research, School of Dentistry, University of Mississippi Medical Center, Jackson, Miss 30216 4505, USA
    Gerontology 48:282-8. 2002
    How aging influences the secretion of saliva is not entirely clear. Postmortem studies have demonstrated that, with age, the parenchyma of the salivary glands is gradually replaced by fat, connective tissue, and oncocytes...
  61. ncbi Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies
    Melanie Bahlo
    The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Victoria, Australia
    Cancer Epidemiol Biomarkers Prev 19:794-8. 2010
    ..performed a multiple sclerosis (MS) GWAS where a substantial component of the cases (24%) had DNA derived from saliva. Genotyping was done on the Illumina genotyping platform using the Infinium Hap370CNV DUO microarray...
  62. ncbi Poor dental status increases acetaldehyde production from ethanol in saliva: a possible link to increased oral cancer risk among heavy drinkers
    N Homann
    Research Unit of Alcohol Diseases, Helsinki University Central Hospital, Helsinki, Finland
    Oral Oncol 37:153-8. 2001
    ..was conducted to evaluate the role of dental status on the microbial production of acetaldehyde from ethanol in saliva. The microbial acetaldehyde production from ethanol was related to the dental score in 132 volunteers...
  63. ncbi Discovery of markers of exposure specific to bites of Lutzomyia longipalpis, the vector of Leishmania infantum chagasi in Latin America
    Clarissa Teixeira
    Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
    PLoS Negl Trop Dis 4:e638. 2010
    ..Though some proteins are immunogenic and have potential as markers of vector exposure, their identity and vector specificity remain elusive...
  64. ncbi The accuracy of self-reported smoking: a systematic review of the relationship between self-reported and cotinine-assessed smoking status
    Sarah Connor Gorber
    Health Measures Analysis Section, Health Information and Research Division, Statistics Canada, 24th Floor R H Coats Building, 100 Tunney s Pasture Driveway, Ottawa, ON, Canada K1A 0T6
    Nicotine Tob Res 11:12-24. 2009
    ..Smoking is a leading cause of premature mortality and preventable morbidity. Surveillance is most often based on self-reported data, but studies have shown that self-reports tend to underestimate smoking status...
  65. ncbi Chikungunya virus and Aedes mosquitoes: saliva is infectious as soon as two days after oral infection
    Mathieu Dubrulle
    Institut Pasteur, Génétique Moléculaire des Bunyavirus, Paris, France
    PLoS ONE 4:e5895. 2009
    ..albopictus. As Ae. albopictus tends to replace Ae. aegypti in many regions, one question remained: is Ae. albopictus as efficient as Ae. aegypti to transmit the variant E1-226V of CHIKV?..
  66. ncbi Effects of Apis mellifera propolis on the activities of streptococcal glucosyltransferases in solution and adsorbed onto saliva-coated hydroxyapatite
    H Koo
    Faculty of Dentistry of Piracicaba, State University of Campinas, Piracicaba, Brazil
    Caries Res 34:418-26. 2000
    ..different regions of Brazil on the activity of separate, purified Gtf enzymes in solution and on the surface of saliva-coated hydroxyapatite (sHA) beads were evaluated...
  67. ncbi Male gamblers have significantly greater salivary cortisol before and after betting on a horse race, than do female gamblers
    C Franco
    Department of Psychology, The University at Albany SUNY, Albany, NY 12222, USA
    Physiol Behav 99:225-9. 2010
    ..Whether these gender differences in HPA activation contribute to gender-related differences in gambling behavior is the subject of ongoing investigation...
  68. ncbi Salivary cortisol response in mother-infant dyads at high psychosocial risk
    E Morelius
    Department of Molecular and Clinical Medicine Division of Paediatrics, Linkoping University Hospital, Linkoping, Sweden
    Child Care Health Dev 33:128-36. 2007
    ..The aim of the present study was to investigate the adrenocortical response to diaper change in mother-infant dyads with psychosocial risk factors...
  69. ncbi Characteristics of biofilm formation by Streptococcus mutans in the presence of saliva
    Sug Joon Ahn
    Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida 32610, USA
    Infect Immun 76:4259-68. 2008
    ..carrying mutations affecting the localization or expression of P1, in the presence of fluid-phase or adsorbed saliva or salivary agglutinin preparations. Whole saliva- and salivary agglutinin-induced aggregation of S...
  70. ncbi Diagnostic accuracy of NicAlert cotinine test strips in saliva for verifying smoking status
    Fiona Cooke
    Market Economics Ltd, Auckland, New Zealand
    Nicotine Tob Res 10:607-12. 2008
    ..Unfortunately, information on the validity and reliability of some test strips in urine and saliva samples is not always available...
  71. ncbi The salivary glands and saliva of Anopheles gambiae as an essential step in the Plasmodium life cycle: a global proteomic study
    Valérie Choumet
    Unité de Biochimie et de Biologie Moléculaire des Insectes, Institut Pasteur, Paris Cedex 15, France
    Proteomics 7:3384-94. 2007
    ..To describe A. gambiae salivary gland and saliva contents, we combined several techniques: 1-DE, 2-DE and LC MS/MS...
  72. ncbi Is the cortisol awakening rise a response to awakening?
    Ines Wilhelm
    Department of Psychobiology, University of Trier, Johanniterufer 15, 54290 Trier, Germany
    Psychoneuroendocrinology 32:358-66. 2007
    ..Although the cortisol awakening response is modulated by circadian influences, it primarily reflects phasic psychophysiological processes specific to the sleep-wake transition...
  73. ncbi Body fat, energy balance and estradiol levels: a study based on hormonal profiles from complete menstrual cycles
    A Ziomkiewicz
    Institute of Anthropology, Polish Academy of Science, Wroclaw, Poland
    Hum Reprod 23:2555-63. 2008
    ..Female fecundity is regulated by nutritional status. Although widely cited, this hypothesis is not strongly supported by empirical data from non-obese, healthy women of reproductive age...
  74. ncbi Exogenous testosterone enhances responsiveness to social threat in the neural circuitry of social aggression in humans
    Erno J Hermans
    Helmholtz Institute, Utrecht University, The Netherlands
    Biol Psychiatry 63:263-70. 2008
    ..Disorders of impulsive aggression in humans have likewise been associated with high testosterone levels, but human evidence for the link between testosterone and aggression remains correlational and inconclusive...
  75. ncbi Chronic maternal stress affects growth, behaviour and hypothalamo-pituitary-adrenal function in juvenile offspring
    Jeff Emack
    CIHR program in Maternal Adversity Vulnerability and Neurodevelopment MAVAN, University of Toronto, 1 King s College Circle, Toronto, Ontario, Canada
    Horm Behav 54:514-20. 2008
    ..In conclusion, CMS leads to modification of growth trajectory, locomotor activity and adrenocortical responses to stress in juvenile offspring. Further, males appear considerably more vulnerable to these effects than females...
  76. ncbi Trypanosoma cruzi infection is enhanced by vector saliva through immunosuppressant mechanisms mediated by lysophosphatidylcholine
    Rafael D Mesquita
    Instituto de Bioquimica Medica, Universidade Federal do Rio de Janeiro, UFRJ, 21940 590, Rio de Janeiro, RJ, Brazil
    Infect Immun 76:5543-52. 2008
    ..However, parasite infection occurs through the wound produced by insect mouthparts. Saliva of the Triatominae bug Rhodnius prolixus is a source of lysophosphatidylcholine (LPC)...
  77. ncbi HPV detection rate in saliva may depend on the immune system efficiency
    Maria Adamopoulou
    Department of Maxillofacial Surgery, University of Athens Medical School, Athens, Greece
    In Vivo 22:599-602. 2008
    ..For example, saliva is an oral fluid that may play a role in HPV transmission, although the detection rates of the virus are lower ..
  78. ncbi Variable cortisol circadian rhythms in children with autism and anticipatory stress
    Blythe A Corbett
    Department of Psychiatry and Behavioral Sciences, The M I N D Institute, Sacramento, CA 95817, USA
    J Psychiatry Neurosci 33:227-34. 2008
    ....
  79. ncbi Dopamine release in response to a psychological stress in humans and its relationship to early life maternal care: a positron emission tomography study using [11C]raclopride
    Jens C Pruessner
    McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montreal, Canada H3A 2B4
    J Neurosci 24:2825-31. 2004
    ..These data suggest that aversive stressful events can be associated with mesolimbic dopamine release in humans, and that the method presented here may be useful to study the effects of early life events on neurobiological stress systems...
  80. ncbi Medication adherence in the MTA: saliva methylphenidate samples versus parent report and mediating effect of concomitant behavioral treatment
    Elizabeth Pappadopulos
    Columbia University, USA
    J Am Acad Child Adolesc Psychiatry 48:501-10. 2009
    ..Moreover, adherence measures often rely on parent report of medication use, and their validity and reliability are unknown...
  81. ncbi Paper-based microfluidic devices for analysis of clinically relevant analytes present in urine and saliva
    Scott A Klasner
    Department of Chemistry, Kansas State University, 213 Chemistry Biochemistry Building, Manhattan, KS 66506, USA
    Anal Bioanal Chem 397:1821-9. 2010
    ..microfluidic chip for the quantification of acetoacetate in artificial urine, as well as nitrite in artificial saliva. Glucose assays were based on those previously demonstrated (Martinez et al...
  82. ncbi Aggregatibacter actinomycetemcomitans builds mutualistic biofilm communities with Fusobacterium nucleatum and Veillonella species in saliva
    Saravanan Periasamy
    Oral Infection and Immunity Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892 4350, USA
    Infect Immun 77:3542-51. 2009
    ..essential for growth, and we investigated multispecies community interactions resulting in mutualistic growth on saliva as the sole nutritional source...
  83. ncbi Moderate versus severe early life stress: associations with stress reactivity and regulation in 10-12-year-old children
    Megan R Gunnar
    Institute of Child Development, University of Minnesota, 51 East River Road, Minneapolis, MN 55455, USA
    Psychoneuroendocrinology 34:62-75. 2009
    ..Lack of effects of severe ELS even for growth delayed children may reflect the restorative effects of adoption or the generally low responsiveness of this age group to the TSST-C...
  84. ncbi Salivary sex hormones during the menstrual cycle
    Peter Celec
    Department of Molecular Biology, Comenius University, Bratislava, Slovakia
    Endocr J 56:521-3. 2009
    ..This study shows that analysis of salivary levels of sex steroids are informative and can be used in neuroendocrine, chronobiological and other research areas, when repeated sampling is needed...
  85. ncbi Detection of Plasmodium falciparum histidine-rich protein II in saliva of malaria patients
    Nana O Wilson
    Morehouse School of Medicine, Department of Microbiology, Biochemistry and Immunology, Atlanta, Georgia 30310, USA
    Am J Trop Med Hyg 78:733-5. 2008
    ..Plasmodium falciparum histidine-rich protein II (PfHRP II) levels in plasma and saliva were compared in malaria-positive and -negative patients in Ghana...
  86. ncbi Day-to-day differences in cortisol levels and molar cortisol-to-DHEA ratios among working individuals
    Min Soo Kim
    Department of Statistics, Chonnam National University, Gwangju, Korea
    Yonsei Med J 51:212-8. 2010
    ..The present study was carried out to determine day-to-day differences in cortisol levels and the molar cortisol-to-dehydroepiandrosterone (DHEA) ratio (molar C/D ratio) in working subjects...
  87. ncbi Increased waking salivary cortisol levels in young people at familial risk of depression
    Zola N Mannie
    Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford OX3 7JX, UK
    Am J Psychiatry 164:617-21. 2007
    ..The present study sought to answer this question by measuring waking salivary cortisol levels in young people at familial risk of depression but with no personal history of mood disorder...
  88. ncbi The role of acetaldehyde outside ethanol metabolism in the carcinogenicity of alcoholic beverages: evidence from a large chemical survey
    Dirk W Lachenmeier
    Chemisches und Veterinaruntersuchungsamt CVUA Karlsruhe, Weissenburger Str 3, D 76187 Karlsruhe, Germany
    Food Chem Toxicol 46:2903-11. 2008
    ..Assuming an equal distribution between the beverage and saliva, the residual acetaldehyde concentrations in the saliva after swallowing could be on average 195 microM for beer, ..
  89. ncbi Cortisol responses to mental stress, exercise, and meals following caffeine intake in men and women
    William R Lovallo
    Veterans Affairs Medical Center, Department of Psychiatry and Behavioral Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Pharmacol Biochem Behav 83:441-7. 2006
    ..00001). Caffeine may elevate cortisol by stimulating the central nervous system in men but may interact with peripheral metabolic mechanisms in women...
  90. ncbi Total antioxidant levels of saliva in children related to caries, age, and gender
    O Tulunoglu
    Department of Pedodontics, Faculty of Dentistry, University of Gazi, Ankara, Turkey
    Int J Paediatr Dent 16:186-91. 2006
    The purpose of this study was to evaluate the relationship between the physicochemical properties of saliva such as flow rate, buffering capacity, pH, calcium level, total protein, total antioxidant status, and dental caries, age, and ..
  91. ncbi Detection of anti-pertussis toxin IgG in oral fluids for use in diagnosis and surveillance of Bordetella pertussis infection in children and young adults
    David J Litt
    Respiratory and Systemic Infection Laboratory and Virus Reference Department, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    J Med Microbiol 55:1223-8. 2006
    ..This oral fluid ELISA will greatly assist in the convenience of B. pertussis disease diagnosis and surveillance...
  92. ncbi Tsetse fly saliva biases the immune response to Th2 and induces anti-vector antibodies that are a useful tool for exposure assessment
    Guy Caljon
    Unit of Cellular and Molecular Immunology, Flanders Interuniversity Institute for Biotechnology VIB, Vrije Universiteit Brussel, Pleinlaan 2, B 1050 Brussels, Belgium
    Int J Parasitol 36:1025-35. 2006
    ..Increasing attention is being paid to the effects of tsetse fly saliva deposited at the feeding site, which enables the blood-feeding process and putatively promotes parasite ..
  93. ncbi Compliance with saliva sampling protocols: electronic monitoring reveals invalid cortisol daytime profiles in noncompliant subjects
    Brigitte M Kudielka
    Department of Experimental Psychology II, , Germany
    Psychosom Med 65:313-9. 2003
    OBJECTIVE: Ambulatory saliva collections for subsequent analysis of free cortisol levels are now frequently applied to measure adrenocortical activity in healthy subjects and patient populations...
  94. ncbi Differences in cortisol awakening response on work days and weekends in women and men from the Whitehall II cohort
    Sabine R Kunz-Ebrecht
    University College London, Department of Epidemiology and Public Health, 1-19 Torrington Place, London WC1E 6BT, UK
    Psychoneuroendocrinology 29:516-28. 2004
    ..by excluding participants who reported a delay of more than 10 min between waking up and taking the first saliva sample...
  95. ncbi Triatoma infestans apyrases belong to the 5'-nucleotidase family
    Eric Faudry
    Chagas' Disease Multidisciplinary Research Laboratory, Department of Pathology, Faculty of Medicine, , Brazil 70.910-900
    J Biol Chem 279:19607-13. 2004
    ..6.1.5) present in a variety of organisms. The apyrase activity found in the saliva of hematophagous insects is correlated with the prevention of ADP-induced platelet aggregation of the host during ..
  96. ncbi Exposure to postnatal depression predicts elevated cortisol in adolescent offspring
    Sarah L Halligan
    Winnicott Research Unit, School of Psychology, University of Reading, 3 Earley Gate, Whiteknights, Reading RG6 6AL, United Kingdom
    Biol Psychiatry 55:376-81. 2004
    ..Because maternal depression confers added risk for depression to children, these alterations might provide a link between early events and later psychopathology...
  97. ncbi Alcohol consumption and cancer of the gastrointestinal tract
    Mikko P Salaspuro
    Research Unit of Substance Abuse Medicine, University Central Hospital of Helsinki, Biomedicum Helsinki, PL 700, 00029 HUS, Helsinki, Finland
    Best Pract Res Clin Gastroenterol 17:679-94. 2003
    ..This results in high local acetaldehyde concentrations in the saliva and contents of the large intestine...
  98. ncbi Assessment of environmental tobacco smoke exposure in children with asthmatic symptoms by questionnaire and cotinine concentrations in plasma, saliva, and urine
    S Willers
    Department of Occupational and Environmental Medicine, Lund University, Sweden
    J Clin Epidemiol 53:715-21. 2000
    ..There were strong correlations between urinary and saliva cotinine concentrations and also, though to a lesser extent, between these media and plasma...
  99. ncbi Correlation between child caries incidence and S. mutans/lactobacilli in saliva after correction for confounding factors
    A Sullivan
    Department of Pedodontics, University of Lund, School of Dentistry, , Sweden
    Community Dent Oral Epidemiol 17:240-4. 1989
    The correlation between caries incidence and Streptococcus mutans/lactobacilli in saliva was studied in two different age groups, followed from ages 5 to 7 and from 12 to 14...
  100. ncbi Associations between stress reactivity and sexual and nonsexual risk taking in young adult human males
    Carolyn Tucker Halpern
    University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27516, USA
    Horm Behav 42:387-98. 2002
    ..Findings are discussed in terms of cross-situational consistency of stress responses, the utility of stress reactivity for understanding individual differences in risk taking, and the interpretive limitations imposed by study design...
  101. ncbi Diurnal cortisol decline is related to coronary calcification: CARDIA study
    Karen Matthews
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Psychosom Med 68:657-61. 2006
    ....

Research Grants76

  1. NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINS
    Frances Walker; Fiscal Year: 2009
    The saliva of the blood-sucking insect, Rhodnius prolixus, originally from the Amazon river basin, which carries the parasite Trypanasoma cruzi, the vector of Chagas' disease, contains a suite of heme proteins that we have named ..
  2. NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINS
    Frances Walker; Fiscal Year: 2009
    The saliva of the blood-sucking insect, Rhodnius prolixus, originally from the Amazon river basin, which carries the parasite Trypanasoma cruzi, the vector of Chagas' disease, contains a suite of heme proteins that we have named ..
  3. Influence of Genetics and Air Pollution Exposures on Birth Outcomes
    Kathleen Mortimer; Fiscal Year: 2007
    ..as low birth weight and premature birth, and (b) evaluate the feasibility of assembling a birth-cohort to provide saliva samples for the analysis of genetic susceptibility to the effects of air pollution on birth outcomes...
  4. The role of sand fly saliva in visceralization of Leishmania parasites.
    Gregory Lanzaro; Fiscal Year: 2007
    It is well known that substances in the saliva of Phlebotomine sand flies enhance pathogenesis of leishmanial parasites in their mammalian hosts and exacerbates the pathology these parasites produce...
  5. The role of sand fly saliva in visceralization of Leishmania parasites
    Gregory Lanzaro; Fiscal Year: 2009
    It is well known that substances in the saliva of Phlebotomine sand flies enhance pathogenesis of leishmanial parasites in their mammalian hosts and exacerbates the pathology these parasites produce...
  6. NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINS
    Frances Walker; Fiscal Year: 2006
    We have discovered a series of heme proteins in the saliva of the blood-sucking bug Rhodnius prolixus that act as vasodilators, anti-platelet aggregation and anti-histaminic agents when injected into the victim...
  7. NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINS
    FRANCES ANN WALKER; Fiscal Year: 2010
    The saliva of the blood-sucking insect, Rhodnius prolixus, originally from the Amazon river basin, which carries the parasite Trypanasoma cruzi, the vector of Chagas'disease, contains a suite of heme proteins that we have named ..
  8. SALIVARY IMMUNE RESPONSE TO COMMENSAL ORAL BACTERIA
    Michael Cole; Fiscal Year: 1993
    ..Secretory immunoglobulin A (SigA) antibodies reactive with commensal bacteria are present in saliva but their impact ont he normal flora is not known...
  9. REGULATION OF IMMUNE RESPONSE IN THE ORAL CAVITY
    Suzanne Michalek; Fiscal Year: 2003
    ..g., teeth. Secretory IgA antibodies in saliva are important in protection against oral diseases, including Streptococcus mutans-induced dental caries, and are ..
  10. DEFINING PRIMARY HHV-6 AND HHV7 INFECTIONS IN CHILDREN
    Danielle Zerr; Fiscal Year: 2003
    ..Data from symptom diaries will be correlated with primary infection as defined by onset of the viruses in saliva. Documentation of seroconversion is the current gold standard for diagnosis of HHV-6 infection, but by definition, ..
  11. IN VIVO STUDIES OF SALIVA ANTIMICROBIAL PROTEINS
    JOEL RUDNEY; Fiscal Year: 2001
    ..In vitro studies have identified saliva proteins involved in each process...
  12. [Ca2+]i and Secretory Dynamics in Parotid Acinar Cells
    David Yule; Fiscal Year: 2007
    b>Saliva is vital for oral health. It is essential for the hydration of the oral mucosa; it provides lubrication, begins nutrient digestion and imparts antimicrobial and mechanical protection for the mouth and upper gastrointestinal tract...
  13. Intra-Oral Biofilm Formation
    Sigmund Socransky; Fiscal Year: 2004
    ..Two important bulk fluids, saliva and GCF, bathe the biofilm surfaces and play and undetermined role in biofilm development...
  14. PMCA Detection of CWD Infection in Cervid and Non-Cervid Species
    EDWARD ARTHUR HOOVER; Fiscal Year: 2010
    ..We have found that infectious prions capable of transmitting CWD are present in the saliva, blood, and urine of CWD-infected deer, potentially explaining the lateral transmission of the disease...
  15. ORAL MUCOSA MICROBIOTA IN HEALTH, CANCER & MUCOSITIS
    Donna Mager; Fiscal Year: 2004
    ..To compare the microbial composition of samples from 8 different oral mucous membrane sites with that found in saliva, supra and sub-gingival plaque in subjects stratified according to periodontal status (health or disease) and ..
  16. Demographic Analysis of Healthy Longevity in China
    Yi Zeng; Fiscal Year: 2009
    ..We plan to collect saliva DNA using Oragene tool kits from voluntary participants among 15,409 interviewees in the sample of about 937 ..