colostrum

Summary

Summary: The thin, yellow, serous fluid secreted by the mammary glands during pregnancy and immediately postpartum before lactation begins. It consists of immunologically active substances, white blood cells, water, protein, fat, and carbohydrates.

Top Publications

  1. ncbi Heat treatment of bovine colostrum. I: effects of temperature on viscosity and immunoglobulin G level
    S McMartin
    Department of Veterinary Population Medicine, University of Minnesota, St. Paul 55108, USA
    J Dairy Sci 89:2110-8. 2006
  2. ncbi Evaluation of the effects of oral colostrum supplementation during the first fourteen days on the health and performance of preweaned calves
    A C B Berge
    College of Veterinary Medicine, Washington State University, Pullman 99164, USA
    J Dairy Sci 92:286-95. 2009
  3. ncbi Colostrum and milk-derived peptide growth factors for the treatment of gastrointestinal disorders
    R J Playford
    Department of Gastroenterology, Imperial College School of Medicine, Hammersmith Hospital, London, UK
    Am J Clin Nutr 72:5-14. 2000
  4. ncbi Immune components of bovine colostrum and milk
    K Stelwagen
    Dairy Science and Technology, AgResearch Ltd, Ruakura Research Centre, Private Bag 3123, Hamilton, 3240 New Zealand
    J Anim Sci 87:3-9. 2009
  5. ncbi Feeding heat-treated colostrum to neonatal dairy heifers: effects on growth characteristics and blood parameters
    J A Elizondo-Salazar
    Department of Dairy and Animal Science, The Pennsylvania State University, University Park 16802, USA
    J Dairy Sci 92:3265-73. 2009
  6. ncbi Bovine colostrum as a biologic in clinical medicine: a review--Part II: clinical studies
    W G Struff
    Center for Transfusion Medicine Muenster, German Red Cross Blood Transfusion Service West gGmbH, Muenster, Germany
    Int J Clin Pharmacol Ther 46:211-25. 2008
  7. ncbi Effect of on-farm commercial batch pasteurization of colostrum on colostrum and serum immunoglobulin concentrations in dairy calves
    S M Godden
    Department of Clinical and Population Sciences, University of Minnesota, St Paul, MN 55108, USA
    J Dairy Sci 86:1503-12. 2003
  8. ncbi Ingestion of colostrum from specific cows induces Bovine Neonatal Pancytopenia (BNP) in some calves
    Annette Friedrich
    Clinic for Ruminants LMU Munich, Oberschleissheim, Germany
    BMC Vet Res 7:10. 2011
  9. ncbi Comparative pathogenicity of nine US porcine reproductive and respiratory syndrome virus (PRRSV) isolates in a five-week-old cesarean-derived, colostrum-deprived pig model
    P G Halbur
    College of Veterinary Medicine, Iowa State University, Ames 50011, USA
    J Vet Diagn Invest 8:11-20. 1996
  10. ncbi Co-administration of the health food supplement, bovine colostrum, reduces the acute non-steroidal anti-inflammatory drug-induced increase in intestinal permeability
    R J Playford
    Department of Gastroenterology, Imperial College School of Medicine, Hammersmith Hospital, Du Cane Road, London W120NN, UK
    Clin Sci (Lond) 100:627-33. 2001

Detail Information

Publications258 found, 100 shown here

  1. ncbi Heat treatment of bovine colostrum. I: effects of temperature on viscosity and immunoglobulin G level
    S McMartin
    Department of Veterinary Population Medicine, University of Minnesota, St. Paul 55108, USA
    J Dairy Sci 89:2110-8. 2006
    The objective of this study was to identify the critical temperature, at or below which heat-treatment of bovine colostrum would produce no significant changes in viscosity, IgG concentration, or Ig activity...
  2. ncbi Evaluation of the effects of oral colostrum supplementation during the first fourteen days on the health and performance of preweaned calves
    A C B Berge
    College of Veterinary Medicine, Washington State University, Pullman 99164, USA
    J Dairy Sci 92:286-95. 2009
    ..The objective of this clinical trial was to determine the effect of colostrum supplementation of the milk replacer ration on morbidity, mortality, feed intake, and weight gain of preweaned ..
  3. ncbi Colostrum and milk-derived peptide growth factors for the treatment of gastrointestinal disorders
    R J Playford
    Department of Gastroenterology, Imperial College School of Medicine, Hammersmith Hospital, London, UK
    Am J Clin Nutr 72:5-14. 2000
    b>Colostrum is the specific first diet of mammalian neonates and is rich in immunoglobulins, antimicrobial peptides, and growth factors...
  4. ncbi Immune components of bovine colostrum and milk
    K Stelwagen
    Dairy Science and Technology, AgResearch Ltd, Ruakura Research Centre, Private Bag 3123, Hamilton, 3240 New Zealand
    J Anim Sci 87:3-9. 2009
    b>Colostrum and milk provide a complete diet for the neonate. In ruminants, colostrum is also the sole source of initial acquired immunity for the offspring. Milk therefore plays an important role in mammalian host defense...
  5. ncbi Feeding heat-treated colostrum to neonatal dairy heifers: effects on growth characteristics and blood parameters
    J A Elizondo-Salazar
    Department of Dairy and Animal Science, The Pennsylvania State University, University Park 16802, USA
    J Dairy Sci 92:3265-73. 2009
    ..lymphocyte counts, health scores, growth, and starter intake after receiving unheated or heat-treated colostrum. First-milking colostrum was collected from Holstein cows and frozen at -20 degrees C to accumulate a large ..
  6. ncbi Bovine colostrum as a biologic in clinical medicine: a review--Part II: clinical studies
    W G Struff
    Center for Transfusion Medicine Muenster, German Red Cross Blood Transfusion Service West gGmbH, Muenster, Germany
    Int J Clin Pharmacol Ther 46:211-25. 2008
    The value of bovine colostrum as a biologic in medicine is documented in clinical trials and supported by relatively large databases containing case reports and anecdotal findings...
  7. ncbi Effect of on-farm commercial batch pasteurization of colostrum on colostrum and serum immunoglobulin concentrations in dairy calves
    S M Godden
    Department of Clinical and Population Sciences, University of Minnesota, St Paul, MN 55108, USA
    J Dairy Sci 86:1503-12. 2003
    ..batch pasteurization on immunoglobulin (IgG) concentrations and the fluid and feeding characteristics of colostrum and to compare serum IgG concentrations in calves fed fresh versus pasteurized colostrum...
  8. ncbi Ingestion of colostrum from specific cows induces Bovine Neonatal Pancytopenia (BNP) in some calves
    Annette Friedrich
    Clinic for Ruminants LMU Munich, Oberschleissheim, Germany
    BMC Vet Res 7:10. 2011
    ..field observations have led to the hypothesis that the aetiological principle may be transmitted to calves via colostrum.The objective of the present study was to verify whether ingestion of colostrum from dams of known BNP calves ..
  9. ncbi Comparative pathogenicity of nine US porcine reproductive and respiratory syndrome virus (PRRSV) isolates in a five-week-old cesarean-derived, colostrum-deprived pig model
    P G Halbur
    College of Veterinary Medicine, Iowa State University, Ames 50011, USA
    J Vet Diagn Invest 8:11-20. 1996
    One hundred forty-six 5-week- old cesarean-derived, colostrum-deprived (CDCD) pigs were inoculated intranasally with 1 of 9 US porcine reproductive and respiratory syndrome virus (PRRSV) isolates...
  10. ncbi Co-administration of the health food supplement, bovine colostrum, reduces the acute non-steroidal anti-inflammatory drug-induced increase in intestinal permeability
    R J Playford
    Department of Gastroenterology, Imperial College School of Medicine, Hammersmith Hospital, Du Cane Road, London W120NN, UK
    Clin Sci (Lond) 100:627-33. 2001
    ..Present prophylactic measures are suboptimal and novel therapies are required. Bovine colostrum is a cheap, readily available source of growth factors, which reduces gastrointestinal injury in rats and mice...
  11. ncbi Soluble CD14 enriched in colostrum and milk induces B cell growth and differentiation
    D Filipp
    Department of Immunology, University of Toronto, and The Arthritis and Immune Disorder Research Centre, The Toronto Hospital, Toronto, ON, Canada M5G 2M9
    Proc Natl Acad Sci U S A 98:603-8. 2001
    ..Consistent with biological activity of sCD14 in vitro, its administration to neonatal mice enhances Ig secretion. The results presented establish sCD14 as a naturally occurring soluble B cell mitogen of mammalian origin...
  12. ncbi Milk immunoglobulins and complement factors
    H Korhonen
    Agricultural Research Centre of Finland, Food Research, FIN 31600 Jokioinen, Finland
    Br J Nutr 84:S75-80. 2000
    The importance of colostrum for the growth and health of newborn offspring is well known...
  13. ncbi Developmental changes in the milk fat globule membrane proteome during the transition from colostrum to milk
    T A Reinhardt
    Periparturient Diseases of Cattle Research Unit, USDA, Agricultural Research Service, National Animal Disease Center, Ames, IA 50010, USA
    J Dairy Sci 91:2307-18. 2008
    ..iTRAQ), was used to quantify protein changes in milk fat globule membranes (MFGM) that were isolated from d 1 colostrum and compared with MFGM from d 7 milk...
  14. ncbi Preoperative oral application of immunoglobulin-enriched colostrum milk and mediator response during abdominal surgery
    Edwin Bölke
    Department of Surgery, University of Ulm, Germany
    Shock 17:9-12. 2002
    ..We conclude that prophylactic oral application of lactobin reduces perioperative endotoxemia and prevents reduction of ENC, suggesting a stabilization of gut barrier during abdominal surgery...
  15. ncbi Antibody responses in serum, colostrum, and milk of swine after infection or vaccination with transmissible gastroenteritis virus
    E H Bohl
    Infect Immun 6:289-301. 1972
    ..with special reference to the titers and the immunoglobulin (Ig) class of TGE neutralizing antibodies in colostrum and milk...
  16. ncbi Bovine colostrum as a biologic in clinical medicine: a review. Part I: biotechnological standards, pharmacodynamic and pharmacokinetic characteristics and principles of treatment
    W G Struff
    Center for Transfusion Medicine, Munster, German Red Cross Blood Transfusion Service West gGmbH, Munster, Germany
    Int J Clin Pharmacol Ther 45:193-202. 2007
    ..In cows, goats, horses and some other animal species, most immunoglobulins are obtained from the colostrum, the first milk after birth, via the gut but in humans the majority of immunoglobulins, and those of the IgG-..
  17. ncbi Postweaning multisystemic wasting syndrome induced after experimental inoculation of cesarean-derived, colostrum-deprived piglets with type 2 porcine circovirus
    S R Bolin
    Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, IA 50010, USA
    J Vet Diagn Invest 13:185-94. 2001
    Cesarean-derived, colostrum-deprived pigs (n = 23) were inoculated intranasally and subcutaneously with a low cell culture passage of type 2 porcine circovirus...
  18. ncbi Analysis of bovine immunoglobulin G in milk, colostrum and dietary supplements: a review
    Leyton W Gapper
    Fonterra Research Centre, Dairy Farm Road, Private Bag 11029, Palmerston North, New Zealand
    Anal Bioanal Chem 389:93-109. 2007
    ..The review also discusses nutraceutical applications, regulatory issues, stability of IgG and the significance of primary reference material in IgG analysis...
  19. ncbi Isolation of bovine immunoglobulins resistant to peptic digestion: new perspectives in the prevention of failure in passive immunization of neonatal calves
    A C R C Porto
    Departamento de Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo, Av Bandeirantes 3900, 14049 900 Ribeirao Preto, Sao Paulo, Brazil
    J Dairy Sci 90:955-62. 2007
    ..and disease susceptibility are greatly influenced by failure in passive immunization, normally provided by colostrum ingestion just after birth...
  20. ncbi Analysis of the presence of cutaneous and mucosal papillomavirus types in ductal lavage fluid, milk and colostrum to evaluate its role in breast carcinogenesis
    Massimiliano Cazzaniga
    Division of Chemoprevention, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy
    Breast Cancer Res Treat 114:599-605. 2009
    ..multiplex PCR-based method the prevalence of alpha mucosal and beta cutaneous HPV DNA in 90 ductal lavages, colostrum and milk...
  21. ncbi Ganglioside composition of differentiated Caco-2 cells resembles human colostrum and neonatal rat intestine
    Kareena L Schnabl
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Br J Nutr 101:694-700. 2009
    ..content and individual ganglioside composition of differentiated Caco-2 cells are similar to those of human colostrum and neonatal rat intestine...
  22. ncbi Effect of supplementing sows' feed with alpha-tocopherol acetate and vitamin C on transfer of alpha-tocopherol to piglet tissues, colostrum, and milk: aspects of immune status of piglets
    A Pinelli-Saavedra
    Centro de Investigacion en Alimentacion y Desarrollo, A C, Carretera a la Victoria, Km 0 6, P O Box 1735, Hermosillo, Sonora 83000, Mexico
    Res Vet Sci 85:92-100. 2008
    ..AT was determined in colostrum, milk, piglet plasma (cord blood) and tissues at birth and on day 21...
  23. ncbi Hyperimmune bovine colostrum in the treatment of shigellosis in children: a double-blind, randomized, controlled trial
    H Ashraf
    ICDDR, B Centre for Health and Population Research, Dhaka, Bangladesh
    Acta Paediatr 90:1373-8. 2001
    ..Hyperimmune bovine colostrum (HBC) is a potentially innovative immunological option in the management of shigellosis together with ..
  24. ncbi Effects of feeding heat-treated colostrum on passive transfer of immune and nutritional parameters in neonatal dairy calves
    J L Johnson
    Department of Veterinary Population Medicine, University of Minnesota, St Paul 55108, USA
    J Dairy Sci 90:5189-98. 2007
    The first objective of this study was to describe the effect of on-farm heat treatment of colostrum on colostral bacteria counts and IgG concentrations. The second objective was to describe the effect of feeding heat-treated (vs...
  25. ncbi GlycoSpectrumScan: fishing glycopeptides from MS spectra of protease digests of human colostrum sIgA
    Nandan Deshpande
    Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, New South Wales, 2109, Australia
    J Proteome Res 9:1063-75. 2010
    ..GlycoSpectrumScan is freely available at www.glycospectrumscan.org ...
  26. ncbi Bovine neonatal immunology
    G M Barrington
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA
    Vet Clin North Am Food Anim Pract 17:463-76. 2001
    ..and dependent on passively acquired maternal immunoglobulins, immune cells, and other substances from colostrum for protection...
  27. ncbi Induction of HIV-1 MPR(649-684)-specific IgA and IgG antibodies in caprine colostrum using a peptide-based vaccine
    Stephanie M Dorosko
    Department of Microbiology and Immunology, Dartmouth Medical School, 1 Medical Center Drive, Lebanon, NH 03756, USA
    Vaccine 26:5416-22. 2008
    Induction of antigen-specific antibodies against HIV-1 in colostrum and milk may help prevent breast milk transmission of the virus...
  28. ncbi Effects of bovine immune and non-immune whey preparations on the composition and pH response of human dental plaque
    V Loimaranta
    Institute of Dentistry and Turku Immunology Centre, University of Turku, Finland
    Eur J Oral Sci 107:244-50. 1999
    ..Thus, the short term rinsing indicates favourable effects of bovine immune whey on human dental plaque...
  29. ncbi Hyperimmune bovine colostrum specific for recombinant Cryptosporidium parvum antigen confers partial protection against cryptosporidiosis in immunosuppressed adult mice
    M C Jenkins
    Immunology and Disease Resistance Laboratory, Agricultural Research Service, USDA, Beltsville, MD 20705, USA
    Vaccine 17:2453-60. 1999
    ..Serum was collected at each immunization and first colostrum was collected after parturition; all were assayed for Cryptosporidium-specific antibodies (Ab)...
  30. ncbi Association of FcRn Heavy Chain Encoding Gene (FCGRT) Polymorphisms with IgG Content in Bovine Colostrum
    Ran Zhang
    State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, People s Republic of China
    Anim Biotechnol 20:242-6. 2009
    ..of the bovine FCGRT (encoding the FcRn heavy chain) and their relationship to the IgG concentration in bovine colostrum. Four single nucleotide polymorphism (SNP), classified into five haplotypes, were identified in a total of 49 ..
  31. ncbi Modulation by colostrum-acquired maternal antibodies of systemic and mucosal antibody responses to rotavirus in calves experimentally challenged with bovine rotavirus
    V Parreño
    Instituto de Virologia, CICV y A, INTA, Castelar, Bs As, Argentina
    Vet Immunol Immunopathol 100:7-24. 2004
    The effect of colostral maternal antibodies (Abs), acquired via colostrum, on passive protection and development of systemic and mucosal immune responses against rotavirus was evaluated in neonatal calves...
  32. ncbi Milk supplemented with immune colostrum: protection against rotavirus diarrhea and modulatory effect on the systemic and mucosal antibody responses in calves experimentally challenged with bovine rotavirus
    V Parreño
    Instituto de Virologia, CICV y A INTA, CC 25, 1712 Castelar, Bs As, Argentina
    Vet Immunol Immunopathol 136:12-27. 2010
    ..All calves received control colostrum (CC; VN=65,536; IgG(1)=16,384) prior to gut closure followed by the milk supplemented with immune colostrum (VN=..
  33. ncbi Effect of heat treatment of bovine colostrum on bacterial counts, viscosity, and Immunoglobulin G concentration
    J A Elizondo-Salazar
    Department of Dairy and Animal Science, The Pennsylvania State University, University Park 16802, USA
    J Dairy Sci 93:961-7. 2010
    A study was conducted to identify the optimal temperature and time at which heat treatment of bovine colostrum would least change viscosity and IgG concentrations yet reduce bacterial count...
  34. ncbi Specific IgG activity against diarrheagenic bacteria in bovine immune milk and effect of pH on its antigen-binding activity upon heating
    Wei Gao
    College of Life Sciences, Nanjing Normal University, Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, and Jiangsu Engineering Research Center for Biomedical Function Materials, Nanjing 210046, P R China
    J Dairy Res 77:220-4. 2010
    Bovine colostrum and milk antibodies of calving and lactating cows immunized with a multivalent vaccine consisting of whole cells of three different species of pathogenic bacteria including four strains of enterotoxigenic Escherischia ..
  35. ncbi Effect of parity on lymphocytes in peripheral blood and colostrum of healthy Holstein dairy cows
    Hiromichi Ohtsuka
    Kitasato University, Towada, Aomori, Japan
    Can J Vet Res 74:130-5. 2010
    ..investigated the leukocyte population and cytokine mRNA levels in peripheral blood mononuclear cells (PBMCs) and colostrum mononuclear cells (CCs) obtained from healthy cows soon after calving...
  36. ncbi Colostrogenesis: mass transfer of immunoglobulin G1 into colostrum
    C R Baumrucker
    Department of Dairy and Animal Science, The Pennsylvania State University, University Park, PA, USA
    J Dairy Sci 93:3031-8. 2010
    ..Mammary IgG(1) appearance in cow colostrum has typically been reported as a concentration and shows IgG(1) concentration to be extremely variable because ..
  37. ncbi A survey of bovine colostrum composition and colostrum management practices on Pennsylvania dairy farms
    S I Kehoe
    Department of Dairy and Animal Science, The Pennsylvania State University, University Park 16802, USA
    J Dairy Sci 90:4108-16. 2007
    b>Colostrum composition and management were surveyed via sample and data collection from 55 dairy farms in Pennsylvania...
  38. ncbi Immunohistochemical identification of porcine reproductive and respiratory syndrome virus (PRRSV) antigen in the heart and lymphoid system of three-week-old colostrum-deprived pigs
    P G Halbur
    Iowa State University, Veterinary Medical Research Institute, Ames 50011, USA
    Vet Pathol 32:200-4. 1995
    ..virus (PRRSV) antigens were detected by a streptavidin-biotin complex technique in tissues of 3-week-old colostrum-deprived pigs that had been inoculated intranasally with PRRSV and had developed moderate respiratory disease...
  39. ncbi Feeding heat-treated colostrum or unheated colostrum with two different bacterial concentrations to neonatal dairy calves
    J A Elizondo-Salazar
    Department of Dairy and Animal Science, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Dairy Sci 92:4565-71. 2009
    The objective of this study was to determine the effects of feeding heat-treated colostrum or unheated colostrum of different bacterial counts on passive transfer of immunity in neonatal dairy calves...
  40. ncbi Relative contribution of colostrum from Maedi-Visna virus (MVV) infected ewes to MVV-seroprevalence in lambs
    V Alvarez
    , Sanidad Animal, 48160-Derio, Vizcaya, Spain
    Res Vet Sci 78:237-43. 2005
    Maedi-visna virus (MVV) seroprevalence associated with consumption of colostrum from seropositive ewes was investigated in 276 housed lambs from birth to 300 days-old...
  41. ncbi Heat-treatment of bovine colostrum. II: effects of heating duration on pathogen viability and immunoglobulin G
    S Godden
    Department of Veterinary Population Medicine, University of Minnesota, St Paul, Minnesota 55108, USA
    J Dairy Sci 89:3476-83. 2006
    Batches (30-L) of first-milking bovine colostrum, inoculated with Mycoplasma bovis (10(8) cfu/mL), Listeria monocytogenes (10(6) cfu/mL), Escherichia coli O157:H7 (10(6) cfu/mL), Salmonella enteritidis (10(6) cfu/mL), and Mycobacterium ..
  42. ncbi Intensification of antiretroviral therapy with raltegravir or addition of hyperimmune bovine colostrum in HIV-infected patients with suboptimal CD4+ T-cell response: a randomized controlled trial
    Helen Byakwaga
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    J Infect Dis 204:1532-40. 2011
    ..This study aimed to determine the effect of intensification of cART with raltegravir or addition of hyperimmune bovine colostrum (HIBC) on CD4(+) T-cell count in such patients.
  43. ncbi Effect of heat and high-pressure treatments on microbiological quality and immunoglobulin G stability of caprine colostrum
    A J Trujillo
    Centre Especial de Recerca Planta de Tecnologia dels Aliments CERPTA, CeRTA, XiT, Departament de Ciencia Animal i dels Aliments, Facultat de Veterinaria, Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain
    J Dairy Sci 90:833-9. 2007
    ..nor Listeria monocytogenes were detected, whereas coagulase-positive staphylococci were found in various colostrum samples with an overall mean of 1.02 log cfu/mL...
  44. ncbi A full belly and colostrum: two major determinants of filial love
    David Val-Laillet
    Laboratoire de Comportement Animal, UMR 6175 CNRS INRA, université de Tours Haras nationaux, 37380 Nouzilly, France
    Dev Psychobiol 45:163-73. 2004
    ..Previous work has shown that colostrum ingestion facilitates the development of a preference for the mother...
  45. ncbi Colostrum obtained from women vaccinated with pneumococcal vaccine during pregnancy inhibits epithelial adhesion of Streptococcus pneumoniae
    Hedwig E Deubzer
    Imperial College, Faculty of Medicine, Department of Immunology, Chelsea and Westminster Hospital, London, United Kingdom
    J Infect Dis 190:1758-61. 2004
    Prevention of nasopharyngeal colonization may reduce the burden of pneumococcal infection during infancy. Colostrum obtained from Gambian mothers who had been vaccinated with either Pneumovax II or Mengivax A&C (n=8 per group) during ..
  46. ncbi Cytokine profiling in human colostrum and milk by protein array
    Miloslav Kverka
    Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Clin Chem 53:955-62. 2007
    Human colostrum and milk contain components that influence development. Our aim was to use a protein array to determine the cytokine profile of human lacteal secretions and changes that occur during the early postpartum period.
  47. ncbi Colostral proteins from cows immunised with Streptococcus mutans/S. sobrinus support the phagocytosis and killing of mutans streptococci by human leucocytes
    V Loimaranta
    Institute of Dentistry, University of Turku, Finland
    J Med Microbiol 48:917-26. 1999
    ..Bovine colostrum inhibits the phagocytic activity of bovine leucocytes and this may reflect the biological activity of ..
  48. ncbi From birth to colostrum: early steps leading to lamb survival
    Raymond Nowak
    Laboratoire de Comportements, Neurobiologie et Adaptation, UMR 6175 CNRS INRA Université François Rabelais Haras Nationaux, Unite de Physiologie de la Reproduction et des Comportements, INRA, 37380 Nouzilly, France
    Reprod Nutr Dev 46:431-46. 2006
    New-born lambs have limited energy reserves and need a rapid access to colostrum to maintain homeothermy and survive. In addition to energy, colostrum provides immunoglobulins which ensure passive systemic immunity...
  49. ncbi Use of immunoglobulin enriched bovine colostrum against oral challenge with enterohaemorrhagic Escherichia coli O157:H7 in mice
    Kenji Funatogawa
    Southern Direct Meat Products Inspection Office, Tochigi, Tochigi 328-0033, Japan
    Microbiol Immunol 46:761-6. 2002
    An immunoglobulin enriched bovine colostrum preparation, IMMULAC (New Zealand Dairy Group, Cambridge, New Zealand), contains antibodies against various bacterial antigens...
  50. ncbi Short communication: Absorption of protein and immunoglobulin g in calves fed a colostrum replacer
    G W Smith
    Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    J Dairy Sci 90:2905-8. 2007
    A well-managed colostrum program on farms is the most important step in reducing disease in neonatal calves...
  51. ncbi Effect of a mixture of micronutrients, but not of bovine colostrum concentrate, on immune function parameters in healthy volunteers: a randomized placebo-controlled study
    Danielle A W Wolvers
    Unilever Food and Health Research Institute, Olivier van Noortlaan 120, NL 3133 AT, Vlaardingen, The Netherlands
    Nutr J 5:28. 2006
    ..effects on immune function are micronutrients such as vitamin C, vitamin E, beta-carotene and zinc, and colostrum. This study was designed to investigate the effects these ingredients on immune function markers in healthy ..
  52. ncbi Sialyl oligosaccharides of human colostrum: changes in concentration during the first three days of lactation
    Sadaki Asakuma
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Japan
    Biosci Biotechnol Biochem 71:1447-51. 2007
    Sialyl oligosaccharides of human milk/colostrum are generally believed to be of biological significance, for example with respect to anti-adhesion of pathogenic organism, providing precursors for biosynthesis of brain, and so on...
  53. ncbi PCR detection of colostrum-associated Maedi-Visna virus (MVV) infection and relationship with ELISA-antibody status in lambs
    V Alvarez
    , Sanidad Animal, 48160-Derio, Vizcaya, Spain
    Res Vet Sci 80:226-34. 2006
    A recent large-scale experimental study showed that bottle-feeding ovine colostrum from seropositive ewes results in high MVV-seroconversion in lambs...
  54. ncbi In vivo antimicrobial and antiviral activity of components in bovine milk and colostrum involved in non-specific defence
    A C van Hooijdonk
    DMV International, R and D Center, PO Box 13, 5460 BA Veghel, The Netherlands
    Br J Nutr 84:S127-34. 2000
    The in vivo evidence of the antimicrobial and antiviral activity of bovine milk and colostrum derived components are reviewed with special emphasis on lactoferrin and lactoperoxidase...
  55. ncbi Survival of rotavirus antibody activity derived from bovine colostrum after passage through the human gastrointestinal tract
    J Pacyna
    Northfield Laboratories Pty Ltd, Oakden, South Australia, Australia
    J Pediatr Gastroenterol Nutr 32:162-7. 2001
    ..Several studies have shown that hyperimmune bovine colostrum, derived from cows immunized with rotavirus, can prevent rotavirus diarrhea when given passively...
  56. ncbi Neutral and acidic oligosaccharides in Holstein-Friesian colostrum during the first 3 days of lactation measured by high performance liquid chromatography on a microfluidic chip and time-of-flight mass spectrometry
    D Barile
    Department of Food Science and Technology, University of California, Davis 95616, USA
    J Dairy Sci 93:3940-9. 2010
    ..In the present work we measured, comprehensively and systematically, free milk OS in the colostrum of 7 Holstein-Friesian cows during the first 3 d of lactation in 12-h intervals by HPLC-chip/time-of-flight mass ..
  57. ncbi An evaluation of Brix refractometry instruments for measurement of colostrum quality in dairy cattle
    V Bielmann
    Department of Population Medicine, University of Guelph, Guelph, Ontario, Canada
    J Dairy Sci 93:3713-21. 2010
    Acquisition of high quality colostrum is an important factor influencing neonatal calf health. Many methods have been used to assess the Ig concentration of colostrum; however, improved, validated evaluation tools are needed...
  58. ncbi Does a calf's motivation to ingest colostrum depend on time since birth, calf vigor, or provision of heat?
    E Vasseur
    Animal Sciences Department, Laval University, Quebec, Quebec, Canada
    J Dairy Sci 92:3915-21. 2009
    Dairy producers often complain that calves have difficulty consuming the recommended amount of colostrum. A better understanding of factors affecting calves' motivation to ingest colostrum could help develop better management...
  59. ncbi Improving passive transfer of immunoglobulins in calves. II: interaction between feeding method and volume of colostrum fed
    S M Godden
    Department of Veterinary Population Medicine, University of Minnesota, St Paul, MN 55108, USA
    J Dairy Sci 92:1758-64. 2009
    ..esophageal tube feeder) on passive transfer of immunoglobulin (Ig) G when either a large or small volume of colostrum was fed...
  60. ncbi Effect of colostrum administration by use of oroesophageal intubation on serum IgG concentrations in Holstein bull calves
    Munashe Chigerwe
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    Am J Vet Res 69:1158-63. 2008
    To determine the amount of colostral IgG required for adequate passive transfer in calves administered colostrum by use of oroesophageal intubation and evaluate the impact of other factors on passive transfer of colostral immunoglobulins ..
  61. ncbi Improving passive transfer of immunoglobulins in calves. I: dose effect of feeding a commercial colostrum replacer
    S M Godden
    Department of Veterinary Population Medicine, University of Minnesota, St Paul, MN 55108, USA
    J Dairy Sci 92:1750-7. 2009
    The objective of this study was to describe the effects of feeding 1 or 2 doses of a commercially available colostrum-derived colostrum replacer (CR) on passive transfer of immunoglobulins (Ig) in newborn dairy calves, including IgG, ..
  62. ncbi Secretory anti-human immunodeficiency virus (HIV) antibodies in colostrum and breast milk are not a major determinant of the protection of early postnatal transmission of HIV
    P Becquart
    Institut National de la Santé et de la Recherche Médicale U430, Hopital Broussais, Paris, France
    J Infect Dis 181:532-9. 2000
    ..These results suggest that humoral mucosal immunity to HIV does not appear as a predominant factor for protection against viral transmission through breast milk...
  63. ncbi Microbial adhesion of Cryptosporidium parvum: identification of a colostrum-derived inhibitory lipid
    Joann Schmidt
    Department of Pathobiology, College of Veterinary Medicine, University of Illinois Urbana, IL 61802, USA
    Mol Biochem Parasitol 162:32-9. 2008
    ..especially dietary sources, of the inhibitory lipid and discovered it was principally derived from bovine colostrum. Interestingly, fresh colostrum yielded little or no inhibitory lipid, however, the lipid was found in ..
  64. ncbi Localization of Mycobacterium avium subspecies paratuberculosis in artificially inoculated milk and colostrum by fractionation
    L Van Brandt
    Institute for Agricultural and Fisheries Research ILVO, Technology and Food Science Unit, Brusselsesteenweg 370, 9090, Melle, Belgium
    J Dairy Sci 93:4722-9. 2010
    ..paratuberculosis (MAP) across the main milk and colostrum fractions (cream, curd, and whey)...
  65. ncbi Health-promoting effects of bovine colostrum in Type 2 diabetic patients can reduce blood glucose, cholesterol, triglyceride and ketones
    Jun Ho Kim
    Department of Food and Biotechnology, Korea University, Jochiwon, Chungnam 339 700, South Korea
    J Nutr Biochem 20:298-303. 2009
    Bovine colostrum (BC) has been reported to enhance immune function, reduce fat accumulation and facilitate the movement of glucose to the muscle...
  66. ncbi Detection of colostrum-derived alloantibodies in calves with bovine neonatal pancytopenia
    Philip Simon Bridger
    Institute for Hygiene and Infectious Diseases of Animals, Justus Liebig University, Frankfurter Strasse 85 89, 35392 Giessen, Germany
    Vet Immunol Immunopathol 141:1-10. 2011
    ..In this study we investigated whether this phenomenon is related to colostrum-derived alloantibodies directed against neonatal leukocytes...
  67. ncbi Size distribution of fat globules in human colostrum, breast milk, and infant formula
    M C Michalski
    INRA UMR 1253, Science et Technologie du Lait et de l Oeuf Agrocampus 65, rue de Saint Brieuc, 35042 Rennes Cedex, France
    J Dairy Sci 88:1927-40. 2005
    ..We measured the MFG size distribution in colostrum and transitional human milk in comparison with fat globules of mature milk and infant formula...
  68. ncbi Identification of minor proteins of human colostrum and mature milk by two-dimensional electrophoresis
    K Murakami
    JCR Biopharmaceuticals Inc, San Diego, CA 92121, USA
    Electrophoresis 19:2521-7. 1998
    ..No major differences in the protein patterns were observed between the minor proteins of colostrum and mature milk, indicating that the minor proteins remained relatively constant during lactation...
  69. ncbi Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum
    Y Habata
    Discovery Research Laboratories 1, Pharmaceutical Discovery Research Division, Takeda Chemical Industries, Ltd, Wadai 10, Tsukuba, Ibaraki, Japan
    Biochim Biophys Acta 1452:25-35. 1999
    ..Moreover, a large amount of apelin (14-93 pmol/ml) was found to be secreted in the bovine colostrum, and it was still detectable even in commercial bovine milk...
  70. ncbi Detection of cytokines in bovine colostrum
    K Hagiwara
    Department of Veterinary Microbiology, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069 8501, Japan
    Vet Immunol Immunopathol 76:183-90. 2000
    b>Colostrum contains factors that are protective for the neonate and may be a source of immunomodulary molecules that positively influence the immune status of the neonate...
  71. ncbi Persistency of high proinflammatory cytokine levels from colostrum to mature milk in preeclampsia
    Ayse Binnur Erbagci
    Department of Biochemistry, Faculty of Medicine, School of Medicine, University of Gaziantep, TR 27310, Gaziantep, Turkey
    Clin Biochem 38:712-6. 2005
    ..Recent evidence suggests a role of an excessive maternal inflammatory response in the pathogenesis of preeclampsia. Whether this imbalance can be transferred from mother to breast milk remains to be established...
  72. ncbi Fractionized milk composition during removal of colostrum and mature milk
    C E Ontsouka
    Institute of Animal Genetics, Nutrition and Housing, University of Berne, Bremgartenstr. 109a, CH-3012 Berne, Switzerland
    J Dairy Sci 86:2005-11. 2003
    Experiments were designed to study compositional differences in colostrum and mature milk and during the course of milk removal...
  73. ncbi Immunoglobulin concentrations in feline colostrum and milk, and the requirement of colostrum for passive transfer of immunity to neonatal kittens
    Melissa A Claus
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, 2015 SW 16th Avenue, University of Florida, Gainesville, FL 32610, USA
    J Feline Med Surg 8:184-91. 2006
    ..have a colostral and milk phase of lactation differentiated by concentrations of immunoglobulins, and whether colostrum ingestion by newborn kittens is essential for optimal transfer of passive immunity...
  74. ncbi Immune components (IgA, IgM, IgG, immune cells) of colostrum of Bangladeshi mothers
    S K Nazrul Islam
    Institute of Nutrition and Food Science, University of Dhaka, Dhaka, Bangladesh
    Pediatr Int 48:543-8. 2006
    b>Colostrum is the first defense for neonates. It is rich in immune components including immunoglobulins and viable immune cells...
  75. ncbi Measurement of bisphenol A concentrations in human colostrum
    Ryoko Kuruto-Niwa
    School of Food and Nutritional Sciences, Laboratory of Microbiology and Host Defenses, University of Shizuoka, 52 1 Yada, Suruga ku, Shizuoka 422 8526, Japan
    Chemosphere 66:1160-4. 2007
    ..In the present study, we measured the concentrations of BPA in human colostrum by a competitive enzyme-linked immunosorbent assay (ELISA) with the aim of understanding the present status of ..
  76. ncbi Bovine colostrum inhibits nuclear factor kappaB-mediated proinflammatory cytokine expression in intestinal epithelial cells
    Min Ji An
    Department of Internal Medicine and Institute of Gastroenterology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea
    Nutr Res 29:275-80. 2009
    b>Colostrum, a nutrient-rich fluid produced by female mammals immediately after giving birth, is loaded with several immune, growth, and tissue repair factors...
  77. ncbi The influence of bovine colostrum supplementation on exercise performance in highly trained cyclists
    C M Shing
    School of Human Movement Studies, The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia
    Br J Sports Med 40:797-801. 2006
    The aim of this experiment was to investigate the influence of low dose bovine colostrum supplementation on exercise performance in cyclists over a 10 week period that included 5 days of high intensity training (HIT).
  78. ncbi Neutrophil function and plasma opsonic capacity in colostrum-fed and colostrum-deprived neonatal kittens
    Rita M Hanel
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    Am J Vet Res 64:538-43. 2003
    ..PROCEDURE: Kittens were randomized at birth into the following treatment groups: colostrum-fed, colostrum-deprived, or colostrum-deprived supplemented with feline or equine IgG...
  79. ncbi Human colostrum: identification of minor proteins in the aqueous phase by proteomics
    David J Palmer
    LactoPharma, School of Biological Sciences, University of Auckland, Auckland, New Zealand
    Proteomics 6:2208-16. 2006
    Human colostrum is an important source of protective, nutritional and developmental factors for the newborn...
  80. ncbi Elevated extrahepatic expression and secretion of mammary-associated serum amyloid A 3 (M-SAA3) into colostrum
    T L McDonald
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198, USA
    Vet Immunol Immunopathol 83:203-11. 2001
    Mammary-associated serum amyloid A 3 (M-SAA3) was secreted at highly elevated levels in bovine, equine and ovine colostrum and found at lower levels in milk 4 days postparturition...
  81. ncbi Variation of major neutral oligosaccharides levels in human colostrum
    S Asakuma
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    Eur J Clin Nutr 62:488-94. 2008
    Human colostrum is known to be important for the protection of infants against infection by pathogenic microorganisms...
  82. ncbi Experimental reproduction of postweaning multisystemic wasting syndrome in cesarean-derived, colostrum-deprived piglets inoculated with porcine circovirus type 2 (PCV2): investigation of quantitative PCV2 distribution and antibody responses
    Y Okuda
    Zen-noh Institute of Animal Health, 7 Ohja-mach, Sakura, Chiba 285-0043, Japan
    J Vet Diagn Invest 15:107-14. 2003
    Sixteen cesarean-derived, colostrum-deprived piglets were inoculated intranasally with porcine circovirus type 2 (PCV2), originally isolated from a pig affected with postweaning multisystemic wasting syndrome (PMWS)...
  83. ncbi Targeted antibodies in dairy-based products
    Lennart Hammarstrom
    Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska University Hospital Huddinge, SE 141 86, Stockholm, Sweden
    Adv Exp Med Biol 606:321-43. 2008
    Bovine colostrum contains immunoglobulins that provide the newborn calf with protection against microbial infections until its own immune system matures...
  84. ncbi Decreased periparturient transmission of bovine leukosis virus in colostrum-fed calves
    Dusty W Nagy
    Departments of Veterinary Medicine and Surgery, University of Missouri Columbia, Columbia, MO 65211, USA
    J Vet Intern Med 21:1104-7. 2007
    The relation between calf bovine leukosis virus (BLV) infection status and colostrum ingestion is unclear. Two conclusions have been drawn from previous studies. One suggests that colostrum ingestion transmits BLV to neonatal calves...
  85. ncbi The effects of bovine colostrum supplementation on body composition and exercise performance in active men and women
    J Antonio
    University of Delaware, Sports Science Laboratory, Newark, Delaware 19176, USA
    Nutrition 17:243-7. 2001
    The purpose of this study was to determine the effect of 8 wk of bovine colostrum supplementation on body composition and exercise performance in active men and women...
  86. ncbi Bovine colostrum contains immunoglobulin G antibodies against intimin, EspA, and EspB and inhibits hemolytic activity mediated by the type three secretion system of attaching and effacing Escherichia coli
    Daniel A Vilte
    Instituto de Patobiologia, Instituto Nacional de Tecnologia Agropecuaria, Buenos Aires, Argentina
    Clin Vaccine Immunol 15:1208-13. 2008
    ..some of which are exported to the host cell via a type three secretion system (TTSS), were identified in bovine colostrum by Western blot analysis. Twenty-seven (77...
  87. ncbi Compartmentalization of small ruminant lentivirus between blood and colostrum in infected goats
    Giuliano Pisoni
    Department of Veterinary Pathology, Hygiene and Public Health, University of Milano, Via Celoria 10, 20133 Milano, Italy
    Virology 369:119-30. 2007
    ..SRLV) subtype A (Maedi-Visna virus) and B (caprine arthritis-encephalitis virus) variants was analyzed in colostrum and peripheral blood mononuclear cells of four naturally infected goats...
  88. ncbi Cytokines in human colostrum and neonatal jaundice
    Vincenzo Zanardo
    Department of Pediatrics, Padua University, 35128 Padua, Italy
    Pediatr Res 62:191-4. 2007
    ..The aim of this study was to investigate whether there is a relationship between cytokine levels in the colostrum of nursing mothers and neonatal jaundice (NJ)...
  89. ncbi Colostrinin proline-rich polypeptide complex from ovine colostrum--a long-term study of its efficacy in Alzheimer's disease
    Jerzy Leszek
    Department of Psychiatry, Medical University of Wrocław, Wrocław, Poland
    Med Sci Monit 8:PI93-6. 2002
    Colostrinin, a proline-rich polypeptide complex (PRP) isolated from ovine colostrum, with immunoregulatory and procognitive properties, has shown positive effects in the treatment of Alzheimer's disease (AD)...
  90. ncbi Bovine colostrum prevents bacterial translocation in an intestinal ischemia/reperfusion-injured rat model
    Han Sung Choi
    Department of Emergency Medicine, Kohwang Medical Research Institute, Kyung Hee University, Seoul, Republic of Korea
    J Med Food 12:37-46. 2009
    This study evaluated whether or not bovine colostrum (BC) is able to treat or prevent intestinal barrier damage, bacterial translocation, and the related systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction ..
  91. ncbi Colostrum and milk as risk factors for infection with Mycobacterium avium subspecies paratuberculosis in dairy cattle
    S S Nielsen
    Department of Large Animal Sciences, Faculty of Life Sciences, University of Copenhagen, Grønnegårdsvej 8, DK 1870 Frederiksberg C, Denmark
    J Dairy Sci 91:4610-5. 2008
    ..Transmission of MAP occurs primarily via feces and in utero, but MAP can also be excreted in colostrum and milk...
  92. ncbi Bovine colostrum modulates cytokine production in human peripheral blood mononuclear cells stimulated with lipopolysaccharide and phytohemagglutinin
    Cecilia M Shing
    School of Human Movement Studies, University of Queensland, St Lucia, Brisbane, Queensland, Australia
    J Interferon Cytokine Res 29:37-44. 2009
    Bovine colostrum has been shown to influence the cytokine production of bovine leukocytes...
  93. ncbi Oropharyngeal administration of colostrum to extremely low birth weight infants: theoretical perspectives
    N A Rodriguez
    Infant Special Care Unit, Department of Pediatrics, Evanston Hospital, Evanston Northwestern Healthcare, Evanston, IL 60201, USA
    J Perinatol 29:1-7. 2009
    ..Own mother's colostrum (OMC) is rich in cytokines and other immune agents that provide bacteriostatic, bacteriocidal, antiviral, anti-..
  94. ncbi A strong association between human earwax-type and apocrine colostrum secretion from the mammary gland
    Kiyonori Miura
    Department of Obstetrics and Gynaecology, Nagasaki University Graduate School of Biomedical Sciences, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
    Hum Genet 121:631-3. 2007
    Here we provided the first genetic evidence for an association between the degree of apocrine colostrum secretion and human earwax type...
  95. ncbi Expression of the neonatal Fc receptor (FcRn) in the bovine mammary gland
    Balazs Mayer
    Department of Physiology and Biochemistry, Faculty of Veterinary Science, Szent Istvan University, PO Box 2, H 1400 Budapest, Hungary
    J Dairy Res 72:107-12. 2005
    In ruminants, protective immunoglobulins are transferred to the newborn via colostrum to mediate maternal immunity...
  96. ncbi Risk factors associated with colostrum quality in Norwegian dairy cows
    S M Gulliksen
    Department of Production Animal Clinical Sciences, Norwegian School of Veterinary Science, Oslo, Norway
    J Dairy Sci 91:704-12. 2008
    The objectives of the present study were to evaluate colostrum quality in Norwegian dairy cows based on IgG content, and to identify associations between possible risk factors and low colostral IgG...
  97. ncbi Does sward height grazed by ewes in mid- to late-pregnancy affect indices of colostrum intake by twin and triplet lambs?
    P R Kenyon
    Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11222, Palmerston North, New Zealand
    N Z Vet J 53:336-9. 2005
    To determine if sward height grazed by ewes in mid- to late-pregnancy affects subsequent indices of colostrum intake by twin and triplet lambs, and the extent of the variation in colostrums intake between twin and triplet litter-mates.
  98. ncbi Inhibition of enteropathogenic Escherichia coli (EPEC) adherence to HEp-2 cells by bovine colostrum and milk
    P Palmeira
    Department of Immunology, , Universidade de So Paulo, So Paulo, Brazil
    Allergol Immunopathol (Madr) 29:229-37. 2001
    ..METHODS: the effect of colostrum, milk, and serum from dairy cows on the adherence to EPEC to HEp-2 cells was investigated...
  99. ncbi Effects of short-term supplementation of clinoptilolite in colostrum and milk on hematology, serum proteins, performance, and health in neonatal dairy calves
    M Mohri
    Department of Clinical Sciences and Center of excellence in Ruminant Abortion and Neonatal Mortality, School of Veterinary Medicine, Ferdowsi University of Mashhad, P O Box 91775 1793, Mashhad, Iran
    Food Chem Toxicol 46:2112-7. 2008
    ..For test 1 group, clinoptilolite in the concentration of 2% of each colostrum meal was added for 48h and for test 2 group, clinoptilolite in the concentration of 2% was added to each ..
  100. ncbi Structural growth, rumen development, and metabolic and immune responses of Holstein male calves fed milk through step-down and conventional methods
    M A Khan
    Dairy Cattle Research Division, National Livestock Research Institute, Cheonan, 330 880, Republic of Korea
    J Dairy Sci 90:3376-87. 2007
    ..In the conventional method, calves (n = 20) were fed colostrum and then milk at a rate of 10% of their BW for the entire period of 44 d...
  101. ncbi The transfer of maternal IgE and other immunoglobulins specific for Trichostrongylus colubriformis larval excretory/secretory product to the neonatal lamb
    A Pfeffer
    AgResearch Ltd, Wallaceville Animal Research Centre, P O Box 40063, Ward Street, Upper Hutt, New Zealand
    Vet Immunol Immunopathol 108:315-23. 2005
    ..Immunoglobulin levels were determined in ewe plasma, colostrum and lamb plasma shortly after birth and before the lambs fed, in lamb plasma 2 days after birth, and lamb plasma,..

Research Grants69

  1. EFFECT OF COLOSTRUM ON GUT MATURATION AND HOST DEFENSE
    W Walker; Fiscal Year: 2009
    ..We will determine how breastfeeding prevents age-related neonatal inflammatory diseases ..
  2. EFFECT OF COLOSTRUM ON GUT MATURATION AND HOST DEFENSE
    W Walker; Fiscal Year: 1993
    We will study the role of colostrum/breast milk in the host defense of the GI tract...
  3. Phase II Clinical Trial of Lactoferrin in Asthma
    Atul Varadhachary; Fiscal Year: 2005
    ..is a multifunctional immunomodulatory protein found in serum and exocrine secretions such as milk and colostrum where it acts as a component of the primary host defense system...
  4. EFFECT OF COLOSTRUM ON GUT MATURATION AND HOST DEFENSE
    W Allan Walker; Fiscal Year: 2010
    ..We will determine how breastfeeding prevents age-related neonatal inflammatory diseases ..
  5. EFFECT OF COLOSTRUM ON GUT MATURATION AND HOST DEFENSE
    W Allan Walker; Fiscal Year: 2010
    ..We will determine how breastfeeding prevents age-related neonatal inflammatory diseases ..
  6. MINIMAL ENTERAL NUTRIENT REQUIREMENTS IN NEONATES
    Douglas Burrin; Fiscal Year: 2004
    ..4) In utero, the fetal intestine is unresponsive to GLP-2. These hypotheses will be tested using a TPN-fed, colostrum-deprived, neonatal pig model with these aims: Aim 1: Quantify the physiological dose response of GLP-2 on ..